$53+ Cheap flights from Mesa, AZ to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/30. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Jun 17 — Jun 241
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to San Diego are usually found in October or September, booked 55 days in advance, depart on a Friday or Thursday and return on a Friday
Cheap flight deals from Mesa to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to San DiegoExplore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 18, 2026.
This Trip.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Fri 7/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/14![Frontier logo]()
$69
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Thu 6/41:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$71
This Frontier deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:40 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Sat 6/134:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/15![Frontier logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:40 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Tue 7/74:17 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 5/17![Frontier logo]()
$73
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Sun 5/241:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$74
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Wed 6/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/13![Frontier logo]()
$76
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:15 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Sun 5/241:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$78
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:15 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Wed 6/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/13![Frontier logo]()
$79
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Fri 5/291:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$81
This Frontier deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:20 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Fri 6/124:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/17![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Tue 5/264:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/14![Frontier logo]()
$83
Best flights from Mesa to San DiegoDiscover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
Discover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 18, 2026.
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:45 am
PHX
- SAN
1 stop3h 50m
Southwest
Wed 6/1010:25 am
SAN
- PHX
1 stop4h 55m
Southwest
Deal found 5/14![Southwest logo]()
$157
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
PHX
- SAN
1 stop3h 51m
Delta
Sat 6/136:15 am
SAN
- PHX
1 stop5h 17m
Delta
Deal found 5/15![Delta logo]()
$266
This Alaska Airlines deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:20 am
PHX
- SAN
Nonstop1h 21m
Alaska Airlines
Mon 9/285:39 pm
SAN
- PHX
Nonstop1h 28m
Alaska Airlines
Deal found 5/13![Alaska Airlines logo]()
$307
This Southwest deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:40 pm
PHX
- SAN
1 stop4h 00m
Southwest
Mon 6/87:45 am
SAN
- PHX
1 stop3h 15m
Southwest
Deal found 5/14![Southwest logo]()
$172
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:20 pm
PHX
- SAN
1 stop4h 20m
Southwest
Wed 9/212:45 pm
SAN
- PHX
1 stop4h 40m
Southwest
Deal found 5/17![Southwest logo]()
$177
This Southwest deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/35:45 am
PHX
- SAN
1 stop4h 10m
Southwest
Wed 7/86:50 pm
SAN
- PHX
1 stop4h 00m
Southwest
Deal found 5/16![Southwest logo]()
$197
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:30 pm
PHX
- SAN
Nonstop1h 10m
Southwest
Fri 6/261:30 pm
SAN
- PHX
2 stops6h 10m
Southwest
Deal found 5/13![Southwest logo]()
$202
This Delta deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1110:35 am
PHX
- SAN
1 stop4h 36m
Delta
Fri 6/126:15 am
SAN
- PHX
1 stop3h 40m
Delta
Deal found 5/15![Delta logo]()
$285
This Alaska Airlines deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/251:05 pm
PHX
- SAN
Nonstop1h 28m
Alaska Airlines
Wed 7/2910:02 pm
SAN
- PHX
Nonstop1h 21m
Alaska Airlines
Deal found 5/17![Alaska Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:45 am
PHX
- SAN
1 stop3h 50m
Southwest
Mon 6/81:30 pm
SAN
- PHX
2 stops6h 10m
Southwest
Deal found 5/13![Southwest logo]()
$232
This Delta deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/61:23 pm
PHX
- SAN
2 stops9h 52m
Delta
Tue 6/910:50 am
SAN
- PHX
1 stop4h 29m
Delta
Deal found 5/14![Delta logo]()
$353
This Southwest deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:30 am
PHX
- SAN
1 stop3h 45m
Southwest
Sun 6/149:55 pm
SAN
- PHX
Nonstop1h 25m
Southwest
Deal found 5/17![Southwest logo]()
$275
Last-minute flights from Mesa to San DiegoDiscover last-minute flight deals from Mesa to San Diego. Data last updated May 18, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to San Diego. Data last updated May 18, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:15 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Sun 5/241:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$78
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Sun 5/241:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$74
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/2411:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Tue 5/264:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/14![Frontier logo]()
$83
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Fri 5/291:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$81
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:15 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Wed 6/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/13![Frontier logo]()
$79
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Thu 6/41:38 pm
SAN
- PHX
Nonstop1h 34m
Frontier
Deal found 5/13![Frontier logo]()
$71
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/111:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Wed 6/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/13![Frontier logo]()
$76
This Trip.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/811:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Fri 7/34:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/14![Frontier logo]()
$69
This Frontier deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/92:20 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Fri 6/124:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/17![Frontier logo]()
$82
This Frontier deal was found by Cheapflights users on 5/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/102:40 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Sat 6/134:17 pm
SAN
- PHX
Nonstop1h 26m
Frontier
Deal found 5/15![Frontier logo]()
$72
One-way flights from Mesa to San DiegoSearch for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
Search for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated May 18, 2026.
This Frontier deal was found by Cheapflights users on 5/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:15 pm
PHX
- SAN
Nonstop1h 16m
Frontier
Deal found 5/17![Frontier logo]()
$53
This Super.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/2511:26 am
PHX
- SAN
Nonstop1h 17m
Frontier
Deal found 5/14![Frontier logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/122:20 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Deal found 5/16![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:32 pm
PHX
- SAN
1 stop10h 16m
Frontier
Deal found 5/16![Frontier logo]()
$59
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/112:20 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Deal found 5/13![Frontier logo]()
$62
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:11 pm
PHX
- SAN
Nonstop1h 18m
Frontier
Deal found 5/13![Frontier logo]()
$63
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/102:20 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Deal found 5/13![Frontier logo]()
$64
This Kiwi.com deal was found by Cheapflights users on 5/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/1010:32 pm
PHX
- SAN
1 stop10h 16m
Frontier
Deal found 5/16![Frontier logo]()
$65
This Super.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/212:20 pm
PHX
- SAN
Nonstop1h 12m
Frontier
Deal found 5/13![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/810:27 pm
PHX
- SAN
1 stop10h 21m
Frontier
Deal found 5/14![Frontier logo]()
$67
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:20 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Deal found 5/13![Frontier logo]()
$68
Find flight deals from Mesa to San Diego
Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated May 18, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $65 (Super.com) |
One-way from | $53 (Frontier) |
Popular in | March |
Cheapest in | October |
Average price | $150 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 6/4
5:45 am-9:35 am
1 stop3h 50m
San Diego
Wed 6/10
10:25 am-3:20 pm
1 stop4h 55m
$157
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 6/5
6:40 pm-10:40 pm
1 stop4h 00m
San Diego
Mon 6/8
7:45 am-11:00 am
1 stop3h 15m
$172
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Mon 8/31
12:20 pm-4:40 pm
1 stop4h 20m
San Diego
Wed 9/2
12:45 pm-5:25 pm
1 stop4h 40m
$177
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 7/3
5:45 am-9:55 am
1 stop4h 10m
San Diego
Wed 7/8
6:50 pm-10:50 pm
1 stop4h 00m
$197
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Tue 6/16
8:30 pm-9:40 pm
Nonstop1h 10m
San Diego
Fri 6/26
1:30 pm-7:40 pm
2 stops6h 10m
$202
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 6/4
5:45 am-9:35 am
1 stop3h 50m
San Diego
Mon 6/8
1:30 pm-7:40 pm
2 stops6h 10m
$232
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 6/12
6:00 am-9:51 am
1 stop3h 51m
San Diego
Sat 6/13
6:15 am-11:32 am
1 stop5h 17m
$266
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Fri 6/12
7:30 am-11:15 am
1 stop3h 45m
San Diego
Sun 6/14
9:55 pm-11:20 pm
Nonstop1h 25m
$275
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 6/11
10:35 am-3:11 pm
1 stop4h 36m
San Diego
Fri 6/12
6:15 am-9:55 am
1 stop3h 40m
$285
Quickest round-trip
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Wed 9/23
8:20 am-9:41 am
Nonstop1h 21m
San Diego
Mon 9/28
5:39 pm-7:07 pm
Nonstop1h 28m
$307
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
PHX-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to San Diego
MS9-SAN
PHX-SAN
What is the cheapest time of day to fly from MS9 to SAN?
Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 18, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 27% on flights from Mesa to San Diego by exploring options for tickets at noon.
What is the cheapest day to fly from Mesa to San Diego?
Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on May 16, 2026.
Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Wednesday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
Weekly flight availability from Mesa to San Diego
Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 18, 2026.
The most flights from MS9 to SAN are scheduled on a Sunday (29 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (11 on average).
How much does it cost to fly round-trip from Mesa to San Diego?
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated May 18, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines,Southwest, andHawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Crew
8.5
Overall
7.9
Boarding
8.1
Entertainment
7.0
Food
7.0
Comfort
7.8
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Related info for your journey
Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
Chula Vista
National City
Coronado
Poway
La Mesa
Julian
Lemon Grove
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Alternative routes for Mesa to San Diego
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Complete your trip
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Search flights from Mesa to San Diego by cabin class
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Mesa and San Diego flights
Browse other Mesa and San Diego flight options. Last updated on May 18, 2026.
Popular flight searches
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Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on May 18, 2026.
Mesa to San Diego flights
Consider these flights traveling from Mesa to San Diego.
Top 6 airlines flying from Mesa to San Diego
Discover the top 6 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 18, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$41 | Average$143 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$48 | Average$139 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$79 | Average$165 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$87 | Average$186 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$97 | Average$220 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$398 | FlexibilityNo cancel fee | On-time69% |