$50+ Cheap flights from Mesa, AZ to San Diego (SAN)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/21. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Aug 7 — Aug 141
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to San Diego are usually found in October or September, booked 27 days in advance, depart on a Thursday or Friday and return on a Friday
Cheap flight deals from Mesa to San Diego
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Best
Last-minute
One-way
Cheapest flights from Mesa to San DiegoExplore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:45 am
PHX
- SAN
Nonstop1h 17m
Frontier
Mon 9/149:57 am
SAN
- PHX
Nonstop1h 28m
Frontier
Deal found 7/7![Frontier logo]()
$78
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:16 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Wed 8/54:45 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/7![Frontier logo]()
$83
This Expedia deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Tue 8/114:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/4![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Mon 8/104:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/3![Frontier logo]()
$85
This Super.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:45 am
PHX
- SAN
Nonstop1h 17m
Frontier
Sat 9/129:57 am
SAN
- PHX
Nonstop1h 28m
Frontier
Deal found 7/3![Frontier logo]()
$86
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Sun 8/236:25 am
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 7/7![Frontier logo]()
$88
This iWofly deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure iWofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Fri 8/286:25 am
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 7/7![Frontier logo]()
$89
This Frontier deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Wed 8/124:45 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/7![Frontier logo]()
$90
This Priceline deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:13 pm
PHX
- SAN
Nonstop1h 22m
Multiple Airlines
Wed 8/196:25 am
SAN
- PHX
Nonstop1h 33m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$93
This Frontier deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Tue 8/114:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/8![Frontier logo]()
$96
Best flights from Mesa to San DiegoDiscover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
Discover carefully curated flight deals from Mesa to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 8, 2026.
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/25:45 am
PHX
- SAN
1 stop3h 25m
Southwest
Wed 9/212:45 pm
SAN
- PHX
1 stop4h 55m
Southwest
Deal found 7/6![Southwest logo]()
$150
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:41 pm
PHX
- SAN
1 stop4h 50m
United Airlines
Thu 8/136:28 pm
SAN
- PHX
1 stop4h 31m
United Airlines
Deal found 7/7![United Airlines logo]()
$157
This Alaska Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2712:13 pm
PHX
- SAN
Nonstop1h 27m
Alaska Airlines
Thu 8/275:39 pm
SAN
- PHX
Nonstop1h 28m
Alaska Airlines
Deal found 7/4![Alaska Airlines logo]()
$162
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:33 am
PHX
- SAN
1 stop5h 02m
United Airlines
Sun 10/185:00 pm
SAN
- PHX
1 stop3h 49m
United Airlines
Deal found 7/7![United Airlines logo]()
$182
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/56:02 am
PHX
- SAN
1 stop3h 31m
Delta
Wed 9/93:00 pm
SAN
- PHX
2 stops7h 13m
Delta
Deal found 7/3![Delta logo]()
$371
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/159:55 am
PHX
- SAN
1 stop5h 00m
Southwest
Tue 9/224:00 pm
SAN
- PHX
1 stop4h 35m
Southwest
Deal found 7/6![Southwest logo]()
$187
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:47 am
PHX
- SAN
1 stop7h 07m
United Airlines
Tue 9/151:24 pm
SAN
- PHX
1 stop5h 11m
United Airlines
Deal found 7/4![United Airlines logo]()
$187
This Southwest deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/228:10 am
PHX
- SAN
1 stop4h 15m
Southwest
Tue 8/2512:45 pm
SAN
- PHX
1 stop4h 40m
Southwest
Deal found 7/5![Southwest logo]()
$187
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:02 am
PHX
- SAN
1 stop4h 13m
Delta
Thu 8/273:00 pm
SAN
- PHX
2 stops9h 12m
Delta
Deal found 7/6![Delta logo]()
$372
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/51:16 pm
PHX
- SAN
2 stops10h 38m
United Airlines
Sat 8/86:20 am
SAN
- PHX
1 stop3h 46m
United Airlines
Deal found 7/4![United Airlines logo]()
$310
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:25 pm
PHX
- SAN
2 stops6h 17m
Delta
Sun 10/186:15 am
SAN
- PHX
1 stop3h 38m
Delta
Deal found 7/7![Delta logo]()
$382
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:25 pm
PHX
- SAN
2 stops6h 17m
Delta
Sun 10/257:59 pm
SAN
- PHX
1 stop3h 25m
Delta
Deal found 7/6![Delta logo]()
$382
Last-minute flights from Mesa to San DiegoDiscover last-minute flight deals from Mesa to San Diego. Data last updated July 8, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to San Diego. Data last updated July 8, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:16 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Wed 8/54:45 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/7![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/42:16 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Tue 8/113:03 pm
SAN
- PHX
1 stop21h 56m
Frontier
Deal found 7/3![Frontier logo]()
$86
This Expedia deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Tue 8/114:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/4![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/62:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Mon 8/104:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/3![Frontier logo]()
$85
This Frontier deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Wed 8/124:45 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/7![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/72:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Thu 8/134:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/7![Frontier logo]()
$100
This Frontier deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Tue 8/114:28 pm
SAN
- PHX
Nonstop1h 29m
Frontier
Deal found 7/8![Frontier logo]()
$96
This Priceline deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/123:13 pm
PHX
- SAN
Nonstop1h 22m
Multiple Airlines
Wed 8/196:25 am
SAN
- PHX
Nonstop1h 33m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$93
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:53 pm
PHX
- SAN
Nonstop1h 30m
Multiple Airlines
Tue 8/186:25 am
SAN
- PHX
Nonstop1h 33m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$101
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Sun 8/236:25 am
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 7/7![Frontier logo]()
$88
This iWofly deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure iWofly is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Fri 8/286:25 am
SAN
- PHX
Nonstop1h 33m
Frontier
Deal found 7/7![Frontier logo]()
$89
One-way flights from Mesa to San DiegoSearch for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
Search for one-way flight options from Mesa to San Diego. Find affordable one-way fares based on user searches. Data last updated July 8, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/2110:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Deal found 7/7![Frontier logo]()
$50
This Frontier deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/410:33 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Deal found 7/3![Frontier logo]()
$51
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/187:00 pm
PHX
- SAN
Nonstop1h 15m
Frontier
Deal found 7/7![Frontier logo]()
$53
This Frontier deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:45 am
PHX
- SAN
Nonstop1h 17m
Frontier
Deal found 7/8![Frontier logo]()
$54
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:58 pm
PHX
- SAN
1 stop16h 10m
Frontier
Deal found 7/3![Frontier logo]()
$57
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/82:32 pm
PHX
- SAN
Nonstop1h 11m
Frontier
Deal found 7/4![Frontier logo]()
$58
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1011:18 am
PHX
- SAN
Nonstop1h 22m
Frontier
Deal found 7/4![Frontier logo]()
$59
This Kiwi.com deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:45 am
PHX
- SAN
Nonstop1h 17m
Frontier
Deal found 7/4![Frontier logo]()
$63
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/57:30 am
PHX
- SAN
Nonstop1h 15m
Southwest
Deal found 7/8![Southwest logo]()
$65
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am
PHX
- SAN
Nonstop1h 15m
Southwest
Deal found 7/7![Southwest logo]()
$66
Find flight deals from Mesa to San Diego
Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated July 8, 2026.
Most accurate provider | Expedia 1 star |
|---|---|
Most trusted provider | Expedia 3 stars |
Round-trip from | $78 (Super.com) |
One-way from | $50 (Kiwi.com) |
Popular in | June |
Cheapest in | October |
Average price | $130 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Wed 9/2
5:45 am-9:10 am
1 stop3h 25m
San Diego
Wed 9/2
12:45 pm-5:40 pm
1 stop4h 55m
$150
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Mon 8/10
7:41 pm-12:31 am
1 stop4h 50m
San Diego
Thu 8/13
6:28 pm-10:59 pm
1 stop4h 31m
$157
Quickest round-trip
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 8/27
12:13 pm-1:40 pm
Nonstop1h 27m
San Diego
Thu 8/27
5:39 pm-7:07 pm
Nonstop1h 28m
$162
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 10/15
6:33 am-11:35 am
1 stop5h 02m
San Diego
Sun 10/18
5:00 pm-8:49 pm
1 stop3h 49m
$182
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Tue 9/15
9:55 am-2:55 pm
1 stop5h 00m
San Diego
Tue 9/22
4:00 pm-8:35 pm
1 stop4h 35m
$187
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Tue 9/8
8:47 am-3:54 pm
1 stop7h 07m
San Diego
Tue 9/15
1:24 pm-6:35 pm
1 stop5h 11m
$187
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Sat 8/22
8:10 am-12:25 pm
1 stop4h 15m
San Diego
Tue 8/25
12:45 pm-5:25 pm
1 stop4h 40m
$187
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Wed 8/5
1:16 pm-11:54 pm
2 stops10h 38m
San Diego
Sat 8/8
6:20 am-10:06 am
1 stop3h 46m
$310
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Sat 9/5
6:02 am-9:33 am
1 stop3h 31m
San Diego
Wed 9/9
3:00 pm-10:13 pm
2 stops7h 13m
$371
PhoenixSan Diego
PHX - SAN
PHXSAN
Phoenix Sky Harbor Intl
Thu 8/20
6:02 am-10:15 am
1 stop4h 13m
San Diego
Thu 8/27
3:00 pm-12:12 am
2 stops9h 12m
$372
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from Mesa to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
PHX-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to San Diego
MS9-SAN
PHX-SAN
What is the cheapest time of day to fly from MS9 to SAN?
Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 8, 2026.
Unlike in the evening, when flights are generally more expensive, you can save up to 28% on flights from Mesa to San Diego by exploring options for tickets at noon.
Weekly flight availability from Mesa to San Diego
Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 8, 2026.
The most flights from MS9 to SAN are scheduled on a Friday (29 on average). You will have fewer flight options on Sunday, which is when the least amount of flights are scheduled (15 on average).
How much does it cost to fly round-trip from Mesa to San Diego?
What is the cheapest day to fly from Mesa to San Diego?
Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on July 4, 2026.
Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Wednesday at noon when fares are most often at their lowest. Sunday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing San Diego
Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 8, 2026.
Peruse reviews from past customers who have flown with Alaska Airlines,Southwest, andHawaiian Airlines from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Overall
7.9
Entertainment
7.0
Comfort
7.8
Crew
8.5
Boarding
8.1
Food
7.1
Reviews
1 / 20
10.0
Excellentrobert,Feb 2026
LAS - SAN
Related info for your journey
Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
Poway
La Mesa
Coronado
Santee
San Ysidro
Julian
Lemon Grove
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Alternative routes for Mesa to San Diego
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Complete your trip
Complete your trip to San Diego by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mesa to San Diego by cabin class
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Mesa and San Diego flights
Browse other Mesa and San Diego flight options. Last updated on July 8, 2026.
Popular flight searches
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Other flights to San Diego
Explore flights to San Diego departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 8, 2026.
Mesa to San Diego flights
Consider these flights traveling from Mesa to San Diego.
Top 6 airlines flying from Mesa to San Diego
Discover the top 6 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$41 | Average$127 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$48 | Average$97 | FlexibilityNo cancel fee | On-time85% | |
| Cheapest$84 | Average$193 | FlexibilityNo cancel fee | On-time75% | |
| Cheapest$89 | Average$185 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$97 | Average$224 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$398 | FlexibilityNo cancel fee | On-time69% |