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$50+ Cheap flights from Mesa, AZ to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/17. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — SAN
Jul 23 — Jul 301
Wed 7/23
Wed 7/30
1 adult, Economy
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Cheapflights Tip: The best prices from Mesa to San Diego are usually found in August or February, booked 80 days in advance, depart on a Saturday or Tuesday and return on a Friday

Cheap flight deals from Mesa to San Diego

Keep the following information in mind while searching for Mesa to San Diego flight deals. Data was last updated July 18, 2025.

Round-trip from

$90
(Cheapflightsfares)

One-way from

$50
(Frontier)

Popular in

March

Cheapest in

August

Average price

$128
From Mesa to San Diego
Search Deals
One-way flight from Mesa to San Diego
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($10 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($3 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Mesa to San Diego

Cheapest flights from Mesa to San Diego
Explore the most affordable flight options available from Mesa to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 18, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1811:16 amPHX - SAN
Nonstop1h 17mFrontier
Sun 9/217:30 pmSAN - PHX
Nonstop1h 30mFrontier
Deal found 7/15$90
This Hawaiian Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Hawaiian Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/236:00 amPHX - SAN
Nonstop1h 17mHawaiian Airlines
Tue 9/238:33 amSAN - PHX
Nonstop1h 41mHawaiian Airlines
Deal found 7/15$91
This American Airlines deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/126:23 pmPHX - SAN
Nonstop1h 15mAmerican Airlines
Tue 8/194:20 pmSAN - PHX
Nonstop1h 27mAmerican Airlines
Deal found 7/15$97
This Southwest deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1410:25 amPHX - SAN
Nonstop1h 20mSouthwest
Mon 8/185:00 pmSAN - PHX
1 stop4h 00mSouthwest
Deal found 7/14$107

Cheapflights Fare Finder

Customize your flight search to find flights from Mesa to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2025.
Use the filters below to find and compare flights from Mesa to San Diego that are best for you.

Fly from

Mesa

Fly to

San Diego

Route

Depart

Return

Price

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 9/23

6:00 am-7:17 am

Nonstop1h 17m

San Diego

Tue 9/23

8:33 am-10:14 am

Nonstop1h 41m

$91

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Fri 8/29

5:40 pm-6:58 pm

Nonstop1h 18m

San Diego

Sun 8/31

2:09 pm-3:36 pm

Nonstop1h 27m

$92

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 8/12

6:23 pm-7:38 pm

Nonstop1h 15m

San Diego

Tue 8/19

4:20 pm-5:47 pm

Nonstop1h 27m

$97

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Thu 8/14

6:35 am-7:50 am

Nonstop1h 15m

San Diego

Thu 8/21

8:45 am-12:50 pm

1 stop4h 05m

$107

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Fri 10/17

6:30 am-7:51 am

Nonstop1h 21m

$50

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sun 11/16

4:15 pm-4:29 pm

Nonstop1h 14m

$57

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Wed 10/15

1:45 pm-6:25 pm

1 stop4h 40m

$58

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sat 11/22

4:15 pm-4:29 pm

Nonstop1h 14m

$66

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Tue 11/25

5:35 pm-5:51 pm

Nonstop1h 16m

$69

PhoenixSan Diego

PHX - SAN

PHXSAN

Phoenix Sky Harbor Intl

Sun 8/17

4:13 pm-7:51 pm

1 stop3h 38m

$89

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/16

Showing 1-10 of 12 results
1
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Best time to book a flight from Mesa to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Mesa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Mesa to San Diego

How far ahead should I book a flight from Mesa to San Diego?

Use this chart to determine the optimal time to book a round-trip flight from Mesa to San Diego. Price data was last updated on July 11, 2025.

Booking 80 days in advance of your planned departure date is, on average, the best time to get cheap flights from Mesa to San Diego. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from Mesa to San Diego?

Currently, August is the cheapest month in which you can book a flight from Mesa to San Diego (average of $286). Flying from Mesa to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MS9 to SAN?

Find hourly flight availability from Mesa to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 18, 2025.

When flying from Mesa to San Diego, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

What is the cheapest day to fly from Mesa to San Diego?

Use this chart to determine the cheapest time to fly round-trip from Mesa to San Diego. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Mesa to San Diego flight should consider departing on Saturday at noon when fares are most often at their lowest. Saturday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Mesa to San Diego

Explore weekly flight availability from Mesa to San Diego. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 18, 2025.

The most flights from MS9 to SAN are scheduled on a Monday (28 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (17 on average).

Reviews of airlines servicing San Diego

Get insights into the airlines that provide service to San Diego. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to San Diego. Reviews last updated July 18, 2025.
Peruse reviews from past customers who have flown with Alaska Airlines, Southwest, and Delta from Mesa to San Diego to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Southwest
8.0
Very good
4,239 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,959 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Hawaiian Airlines
7.8
Good
2,581 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,864 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Entertainment

7.1

Comfort

7.8

Crew

8.5

Overall

8.0

Food

7.1

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from Mesa to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Mesa?

    Located just 2.6 mi from the city center, San Diego is the airport most travelers will use when flying to San Diego from Mesa. Booking flights from Mesa to San Diego (SAN) should be relatively easy as there are 24 daily inbound flights from Mesa from 7 different airlines.

  • What are the cheapest airlines to fly from Mesa to San Diego one-way?

    The cheapest airline one-way is Frontier, with whom users have recently found tickets for as low as $50. However, be on the lookout for offers from Alaska Airlines and Southwest, as they are both options that can get you from Mesa to San Diego for a low price.

  • What are the most reliable airlines from Mesa to San Diego?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Mesa to San Diego on time: Frontier (83%), Southwest (72%), Japan Airlines (67%).

  • What are the cheapest flights from Mesa to San Diego?

    While on average a flight from Mesa to San Diego is generally $947, our data shows the cheapest flight currently is $44. When looking at the most popular route, (Phoenix Sky Harbor Intl - San Diego), you can expect to pay $74 for that flight.

  • Can I find deals for flights from Mesa to San Diego that include hotel bookings?

    Yes. In addition to deals on Mesa to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Mesa to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Mesa to San Diego.

  • Can I find deals for business class flights from Mesa to San Diego?

    Yes. Cheapflights offers flight deals from Mesa to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Mesa to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Mesa to San Diego (average of $286). Flying from Mesa to San Diego in March is currently the most expensive (average of $366). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
Coronado
Poway
National City
Lemon Grove
Imperial Beach
La Mesa
Alpine
Santee

Browse thousands of different options on Cheapflights for your next trip

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Top 7 airlines flying from Mesa to San Diego

Discover the top 7 airlines that operate flights from Mesa to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$35Average$133FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$47Average$108FlexibilityNo cancel feeOn-time65%
Alaska AirlinesCheapest$117Average$297FlexibilityNo cancel feeOn-time75%
American AirlinesCheapest$119Average$241FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$122Average$248FlexibilityNo cancel feeOn-time63%
Hawaiian AirlinesCheapest$137Average$227FlexibilityNo cancel feeOn-time85%
United AirlinesCheapest$269Average$404FlexibilityNo cancel feeOn-time69%

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