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$86+ Cheap flights from Indiana to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/23. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SAN
May 28 — Jun 41
Thu 5/28
Thu 6/4
1 adult, Economy
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Cheap flight deals from Indiana to San Diego

Cheapest flights from Indiana to San Diego
Explore the most affordable flight options available from Indiana to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 28, 2026.

This Southwest deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:45 am
MDW
-
SAN
Nonstop4h 15m
Southwest
Sat 5/1610:40 pm
SAN
-
MDW
Nonstop3h 55m
Southwest
Deal found 4/23$227
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/132:10 pm
ORD
-
SAN
Nonstop4h 38m
Alaska Airlines
Sat 5/1612:34 pm
SAN
-
ORD
Nonstop4h 16m
Alaska Airlines
Deal found 4/23$227
This Expedia deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/129:37 pm
ORD
-
SAN
1 stop28h 13m
Multiple Airlines
Sat 5/165:44 pm
SAN
-
ORD
Nonstop4h 11m
Multiple Airlines
Deal found 4/23$228
This United Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:05 am
ORD
-
SAN
Nonstop4h 37m
United Airlines
Wed 5/278:32 pm
SAN
-
ORD
1 stop6h 19m
United Airlines
Deal found 4/23$229
This Frontier deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/239:37 pm
ORD
-
SAN
1 stop13h 05m
Frontier
Thu 5/289:37 am
SAN
-
ORD
1 stop8h 55m
Frontier
Deal found 4/23$230
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
MDW
-
SAN
2 stops43h 50m
Frontier
Sat 5/306:25 am
SAN
-
MDW
1 stop29h 47m
Frontier
Deal found 4/24$231
This Expedia deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/119:37 pm
ORD
-
SAN
1 stop28h 13m
Frontier
Thu 5/146:25 am
SAN
-
ORD
1 stop7h 51m
Frontier
Deal found 4/25$231
This Kiwi.com deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/259:37 pm
ORD
-
SAN
1 stop28h 13m
Frontier
Mon 6/810:07 pm
SAN
-
ORD
1 stop29h 25m
Frontier
Deal found 4/24$233
This Expedia deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/139:37 pm
ORD
-
SAN
1 stop13h 05m
Multiple Airlines
Tue 5/1912:34 pm
SAN
-
ORD
Nonstop4h 16m
Multiple Airlines
Deal found 4/24$234
This Alaska Airlines deal was found by Cheapflights users on 4/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:00 am
ORD
-
SAN
Nonstop4h 37m
Alaska Airlines
Sat 5/305:44 pm
SAN
-
ORD
Nonstop4h 11m
Alaska Airlines
Deal found 4/23$235
This CheapOair deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/199:37 pm
ORD
-
SAN
1 stop28h 13m
Frontier
Tue 5/269:37 am
SAN
-
ORD
1 stop8h 55m
Frontier
Deal found 4/27$236
This Southwest deal was found by Cheapflights users on 4/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/236:10 pm
MDW
-
SAN
Nonstop4h 20m
Southwest
Sat 6/610:40 pm
SAN
-
MDW
Nonstop4h 00m
Southwest
Deal found 4/24$237

Find flight deals from Indiana to San Diego

Keep the following information in mind while searching for Indiana to San Diego flight deals. Data was last updated April 28, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$227
(Southwest)

One-way from

$86
(Orbitz)

Popular in

March

Cheapest in

May

Average price

$337

Good round-trip deal

$490 or less

Good one-way deal

$264 or less
Provider with most accurate pricing for Indianapolis-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-San Diego flights.
Search Deals
From Indiana to San Diego
Search Deals
One-way flight from Indiana to San Diego
Search Deals
Highest demand for flights based on searches. 1% potential increase in price ($6 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals
Price to beat on a round-trip flight from Indiana to San Diego.
Search Deals
Price to beat on a one-way flight from Indiana to San Diego.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
Use the filters below to find and compare flights from Indiana to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Tue 5/19

9:00 am-11:37 am

Nonstop4h 37m

San Diego

Sat 5/23

12:34 pm-6:50 pm

Nonstop4h 16m

$247

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 5/27

3:47 pm-7:51 pm

1 stop6h 04m

San Diego

Wed 6/3

4:41 pm-10:59 pm

Nonstop4h 18m

$247

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Fri 5/22

6:00 am-9:28 am

1 stop6h 28m

San Diego

Mon 5/25

10:40 pm-9:28 am

1 stop7h 48m

$266

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Thu 5/14

9:22 am-2:20 pm

1 stop6h 58m

San Diego

Sat 5/16

6:15 am-4:32 pm

1 stop8h 17m

$271

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Mon 6/1

8:45 pm-11:10 pm

Nonstop4h 25m

San Diego

Wed 6/3

10:40 pm-4:35 am

Nonstop3h 55m

$277

LouisvilleSan Diego

SDF - SAN

SDFSAN

Louisville Intl

Tue 9/8

7:20 am-2:08 pm

1 stop9h 48m

San Diego

Tue 9/15

6:15 am-5:41 pm

1 stop8h 26m

$277

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 5/28

5:19 pm-10:00 pm

1 stop6h 41m

San Diego

Wed 6/3

12:41 pm-12:08 am

1 stop9h 27m

$287

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Sat 5/23

11:09 am-6:01 pm

1 stop8h 52m

San Diego

Mon 5/25

6:30 am-4:51 pm

1 stop8h 21m

$287

IndianapolisSan Diego

IND - SAN

INDSAN

Indianapolis

Mon 6/8

7:15 pm-11:15 pm

1 stop7h 00m

San Diego

Sat 6/13

3:00 pm-1:15 am

1 stop7h 15m

$289

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Tue 6/2

5:00 am-9:05 am

1 stop6h 05m

San Diego

Thu 6/4

4:41 pm-10:59 pm

Nonstop4h 18m

$293

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Indiana to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to San Diego

How far ahead should I book a flight from Indiana to San Diego?

The price you pay for your flight from Indiana to San Diego may vary depending on when you book. For the best chance of a lower fare, look to book 54 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Indiana to San Diego?

Currently, November is the cheapest month in which you can book a flight from Indiana to San Diego (average of $78). Flying from Indiana to San Diego in March is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SAN?

Find hourly flight availability from Indiana to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 28, 2026.

It’s typically best to fly out from Indiana to San Diego in the afternoon. Doing so could potentially save you 15% on the flight price compared to flying in the evening, which is usually more expensive.

How much does it cost to fly round-trip from Indiana to San Diego?

Related info for your journey

Find useful and relevant information for your journey from Indiana to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Indiana?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to San Diego from Indiana.

  • How popular is this Indiana to San Diego flight route?

    The Indiana to San Diego flight path was viewed by 14 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indiana to San Diego?

    For as low as $247, Alaska Airlines can have you in San Diego from Indiana in 4h 37m. Indiana and San Diego are separated by a distance of 1719 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indiana to San Diego one-way?

    The cheapest airlines for a one-way flight from Indiana to San Diego are Spirit Airlines ($55), Frontier ($82), and United Airlines ($108).

  • What are the most popular routes from Indiana to San Diego?

    The most popular route from Indiana to San Diego is Chicago O'Hare Intl - San Diego. You may also consider Chicago Midway - San Diego or Indianapolis - San Diego.

  • What are the cheapest flights from Indiana to San Diego?

    Looking for the cheapest flight from Indiana to San Diego? While on average our users pay $470, our data indicates the cheapest price to be $184. The most popular route (Chicago O'Hare Intl - San Diego), is priced around $214.

  • Can I find deals for flights from Indiana to San Diego that include hotel bookings?

    Yes. In addition to deals on Indiana to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to San Diego.

  • Can I find deals for business class flights from Indiana to San Diego?

    Yes. Cheapflights offers flight deals from Indiana to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to San Diego?

    Currently, November is the cheapest month in which you can book a flight from Indiana to San Diego (average of $78). Flying from Indiana to San Diego in March is currently the most expensive (average of $197). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

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Alternative routes for Indiana to San Diego

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Top 6 airlines flying from Indiana to San Diego

Discover the top 6 airlines that operate flights from Indiana to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 28, 2026.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$73Average$203FlexibilityNo cancel feeOn-time65%
FrontierCheapest$86Average$245FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$197Average$425FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$220Average$409FlexibilityNo cancel feeOn-time69%
DeltaCheapest$234Average$381FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$276Average$444FlexibilityNo cancel feeOn-time63%

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