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$72+ Cheap flights from Indiana to San Diego (SAN)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/14. Fares are subject to change and may not be available on all flights or dates of travel.
IND — SAN
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Indiana to San Diego

Cheapest flights from Indiana to San Diego
Explore the most affordable flight options available from Indiana to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Trip.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:53 pm
ORD
-
SAN
1 stop8h 09m
Multiple Airlines
Sat 4/187:55 am
SAN
-
ORD
Nonstop4h 26m
Multiple Airlines
Deal found 3/5$171
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:25 pm
MDW
-
SAN
2 stops31h 37m
Frontier
Wed 4/1512:29 pm
SAN
-
MDW
1 stop24h 35m
Frontier
Deal found 3/8$172
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/148:58 pm
ORD
-
SAN
1 stop18h 19m
Frontier
Sat 4/187:15 am
SAN
-
ORD
2 stops13h 24m
Frontier
Deal found 3/5$172
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:15 am
MDW
-
SAN
Nonstop4h 15m
Southwest
Sat 4/186:45 am
SAN
-
MDW
1 stop5h 40m
Southwest
Deal found 3/8$173
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/218:58 pm
ORD
-
SAN
1 stop18h 19m
Frontier
Tue 4/282:12 pm
SAN
-
ORD
1 stop13h 56m
Frontier
Deal found 3/7$173
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:15 am
MDW
-
SAN
1 stop10h 10m
Frontier
Sun 5/103:20 pm
SAN
-
MDW
1 stop21h 29m
Frontier
Deal found 3/5$174
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/127:55 am
ORD
-
SAN
1 stop25h 26m
Frontier
Sat 4/187:15 am
SAN
-
ORD
1 stop24h 30m
Frontier
Deal found 3/10$174
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:53 pm
ORD
-
SAN
1 stop8h 09m
Frontier
Sat 4/187:15 am
SAN
-
ORD
2 stops13h 24m
Frontier
Deal found 3/5$175
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/288:58 pm
ORD
-
SAN
1 stop18h 19m
Frontier
Tue 5/511:42 am
SAN
-
ORD
2 stops21h 02m
Frontier
Deal found 3/6$176
This Trip.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/132:29 pm
ORD
-
SAN
1 stop11h 33m
Frontier
Fri 4/178:49 pm
SAN
-
ORD
1 stop7h 19m
Frontier
Deal found 3/7$177
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:10 am
MDW
-
SAN
2 stops8h 15m
Southwest
Sat 5/910:40 pm
SAN
-
MDW
Nonstop3h 55m
Southwest
Deal found 3/7$178
This Kiwi.com deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:53 pm
ORD
-
SAN
1 stop8h 09m
Frontier
Sun 4/196:56 pm
SAN
-
ORD
2 stops36h 44m
Frontier
Deal found 3/8$178

Find flight deals from Indiana to San Diego

Keep the following information in mind while searching for Indiana to San Diego flight deals. Data was last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$171
(Trip.com)

One-way from

$72
(Trip.com)

Popular in

December

Cheapest in

May

Average price

$375

Good round-trip deal

$376 or less

Good one-way deal

$234 or less
Provider with most accurate pricing for Indianapolis-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Indianapolis-San Diego flights.
Search Deals
From Indiana to San Diego
Search Deals
One-way flight from Indiana to San Diego
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Indiana to San Diego.
Search Deals
Price to beat on a one-way flight from Indiana to San Diego.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Indiana to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Indiana to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 4/29

4:00 pm-8:12 pm

1 stop6h 12m

San Diego

Sat 5/2

10:40 pm-4:45 am

Nonstop4h 05m

$200
Quickest round-trip

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Mon 4/13

6:40 am-8:55 am

Nonstop4h 15m

San Diego

Tue 4/21

10:40 pm-4:35 am

Nonstop3h 55m

$217

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 4/16

7:59 pm-10:41 pm

Nonstop4h 42m

San Diego

Tue 4/21

12:15 pm-6:40 pm

Nonstop4h 25m

$217

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Fri 4/17

8:45 pm-11:10 pm

Nonstop4h 25m

San Diego

Tue 4/21

10:40 pm-4:35 am

Nonstop3h 55m

$217

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Wed 4/22

7:00 am-9:40 am

Nonstop4h 40m

San Diego

Sat 4/25

3:04 pm-12:45 am

1 stop7h 41m

$217

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Tue 3/31

8:10 am-3:05 pm

2 stops8h 55m

San Diego

Tue 4/7

9:00 pm-5:45 am

1 stop6h 45m

$218

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Tue 4/14

7:16 pm-11:38 pm

1 stop6h 22m

San Diego

Tue 4/21

6:15 am-5:58 pm

1 stop9h 43m

$237

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Thu 4/23

7:00 am-9:40 am

Nonstop4h 40m

San Diego

Mon 4/27

6:20 am-12:34 pm

Nonstop4h 14m

$237

ChicagoSan Diego

MDW - SAN

MDWSAN

Chicago Midway

Thu 5/7

6:40 am-8:55 am

Nonstop4h 15m

San Diego

Mon 5/11

10:40 pm-4:35 am

Nonstop3h 55m

$237

ChicagoSan Diego

ORD - SAN

ORDSAN

Chicago O'Hare Intl

Fri 4/10

8:20 pm-10:59 pm

Nonstop4h 39m

San Diego

Mon 4/20

10:30 pm-4:35 am

Nonstop4h 05m

$237

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/9

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Indiana to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Indiana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Indiana to San Diego

What is the cheapest month to book a flight from Indiana to San Diego?

Currently, August is the cheapest month in which you can book a flight from Indiana to San Diego (average of $125). Flying from Indiana to San Diego in June is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IN to SAN?

Find hourly flight availability from Indiana to San Diego. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 10, 2026.

It’s typically best to fly out from Indiana to San Diego in the morning. Doing so could potentially save you 24% on the flight price compared to flying in the evening, which is usually more expensive.

Related info for your journey

Find useful and relevant information for your journey from Indiana to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to San Diego from Indiana?

    Located just 2.6 mi from the city center, San Diego (SAN) is the airport most travelers will use when flying to San Diego from Indiana.

  • How popular is this Indiana to San Diego flight route?

    The Indiana to San Diego flight path was viewed by 13 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from Indiana to San Diego?

    For as low as $217, United Airlines can have you in San Diego from Indiana in 4h 15m. Indiana and San Diego are separated by a distance of 1725 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Indiana to San Diego one-way?

    The cheapest airlines for a one-way flight from Indiana to San Diego are Spirit Airlines ($50), Frontier ($82), and American Airlines ($109).

  • What are the most popular routes from Indiana to San Diego?

    The most popular route from Indiana to San Diego is Chicago O'Hare Intl - San Diego. You may also consider Chicago Midway - San Diego or Indianapolis - San Diego.

  • What are the cheapest flights from Indiana to San Diego?

    Looking for the cheapest flight from Indiana to San Diego? While on average our users pay $390, our data indicates the cheapest price to be $211. The most popular route (Chicago O'Hare Intl - San Diego), is priced around $163.

  • Can I find deals for flights from Indiana to San Diego that include hotel bookings?

    Yes. In addition to deals on Indiana to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Indiana to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Indiana to San Diego.

  • Can I find deals for business class flights from Indiana to San Diego?

    Yes. Cheapflights offers flight deals from Indiana to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Indiana to San Diego?

    Currently, August is the cheapest month in which you can book a flight from Indiana to San Diego (average of $125). Flying from Indiana to San Diego in June is currently the most expensive (average of $227). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
Chula Vista
National City
Coronado
La Mesa
Poway
Julian
Lemon Grove

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Indiana to San Diego

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Indiana to San Diego

Discover the top 6 airlines that operate flights from Indiana to San Diego. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$86Average$244FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$99Average$206FlexibilityNo cancel feeOn-time65%
American AirlinesCheapest$200Average$417FlexibilityNo cancel feeOn-time71%
DeltaCheapest$203Average$377FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$204Average$379FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$278Average$432FlexibilityNo cancel feeOn-time63%

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