$583+ Cheap flights from Greenville, NC to San Diego (PGV - SAN)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SAN
Oct 30 — Nov 61
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Greenville to San Diego with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Greenville to San Diego
Cheapest
Best
Last-minute
One-way
Cheapest flights from Greenville to San DiegoExplore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop9h 03m
Tue 11/36:15 am -
1 stop7h 35m
Deal found 9/29![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:24 am -
1 stop8h 57m
Sat 10/1711:58 am -
1 stop8h 58m
Deal found 9/28![American Airlines logo]()
$645
Best flights from Greenville to San DiegoDiscover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from Greenville to San Diego that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop9h 03m
Tue 11/36:15 am -
1 stop7h 35m
Deal found 9/29![American Airlines logo]()
$583
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop9h 03m
Mon 11/26:25 am -
2 stops13h 33m
Deal found 9/29![American Airlines logo]()
$597
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/110:57 am -
2 stops13h 45m
Thu 1/76:15 am -
1 stop7h 31m
Deal found 9/28![American Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:05 am -
1 stop9h 03m
Mon 11/211:29 am -
1 stop8h 29m
Deal found 9/29![American Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:24 am -
1 stop8h 57m
Sat 10/1711:58 am -
1 stop8h 58m
Deal found 9/28![American Airlines logo]()
$645
Last-minute flights from Greenville to San DiegoDiscover last-minute flight deals from Greenville to San Diego. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from Greenville to San Diego. Data last updated September 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:24 am -
1 stop8h 57m
Sat 10/1711:58 am -
1 stop8h 58m
Deal found 9/28![American Airlines logo]()
$645
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:05 am -
1 stop9h 03m
Tue 11/36:15 am -
1 stop7h 35m
Deal found 9/29![American Airlines logo]()
$583
One-way flights from Greenville to San DiegoSearch for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from Greenville to San Diego. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:05 am -
1 stop7h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![American Airlines logo]()
$614
Find flight deals from Greenville to San Diego
Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 30, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $583 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Fri 10/30
5:05 am-11:08 am
1 stop9h 03m
San Diego
Tue 11/3
6:15 am-4:50 pm
1 stop7h 35m
$583
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Fri 10/30
5:05 am-11:08 am
1 stop9h 03m
San Diego
Mon 11/2
6:25 am-10:58 pm
2 stops13h 33m
$597
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Sun 11/15
5:05 am-11:09 am
1 stop9h 04m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$614
Quickest round-trip
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Thu 10/15
5:05 am-9:10 am
1 stop7h 05m
San Diego
Wed 12/31
12:00 am-3:00 am
Nonstop0h 00m
$614
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Fri 1/1
10:57 am-9:42 pm
2 stops13h 45m
San Diego
Thu 1/7
6:15 am-4:46 pm
1 stop7h 31m
$624
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Thu 10/29
5:05 am-11:08 am
1 stop9h 03m
San Diego
Mon 11/2
11:29 am-10:58 pm
1 stop8h 29m
$645
GreenvilleSan Diego
PGV Pitt-Greenville - SAN San Diego
PGVSAN
Pitt-Greenville
Tue 10/13
6:24 am-12:21 pm
1 stop8h 57m
San Diego
Sat 10/17
11:58 am-11:56 pm
1 stop8h 58m
$645
Sorted by cheapest first
Compare providers for flights from Greenville to San Diego
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Greenville, North Carolina-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville, North Carolina-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-San Diego flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Greenville, North Carolina-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Greenville to San Diego
Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
PGV-SAN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Related info for your journey
Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near San Diego?
Book flights to San Diego if you plan to visit one of these locationsEl Cajon
National City
Chula Vista
San Ysidro
Poway
Coronado
La Mesa
Julian
Santee
Lemon Grove
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Greenville
Popular flights
San Diego flight routes