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$477+ Cheap flights from Greenville, NC to San Diego (PGV - SAN)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/2. Fares are subject to change and may not be available on all flights or dates of travel.
PGV — SAN
Jun 5 — Jun 121
Fri 6/5
Fri 6/12
1 adult, Economy
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Cheap flight deals from Greenville to San Diego

Cheapest flights from Greenville to San Diego
Explore the most affordable flight options available from Greenville to San Diego. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 6, 2026.

This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:10 am
PGV
-
SAN
1 stop6h 50m
American Airlines
Thu 7/910:28 pm
SAN
-
PGV
1 stop9h 07m
American Airlines
Deal found 5/5$477
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:00 am
PGV
-
SAN
1 stop10h 13m
American Airlines
Sat 5/236:50 am
SAN
-
PGV
1 stop7h 48m
American Airlines
Deal found 5/4$597
This American Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/56:00 am
PGV
-
SAN
1 stop8h 08m
American Airlines
Sat 5/91:31 pm
SAN
-
PGV
1 stop7h 25m
American Airlines
Deal found 5/1$615
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/245:10 am
PGV
-
SAN
1 stop6h 54m
American Airlines
Fri 5/297:15 pm
SAN
-
PGV
2 stops25h 43m
American Airlines
Deal found 5/2$707
This American Airlines deal was found by Cheapflights users on 5/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:10 am
PGV
-
SAN
1 stop6h 54m
American Airlines
Fri 5/297:15 pm
SAN
-
PGV
2 stops19h 23m
American Airlines
Deal found 5/2$730

Find flight deals from Greenville to San Diego

Discover tips and strategies to find the most affordable flight options for your journey from Greenville (PGV) to San Diego (SAN). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 6, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$477
(American Airlines)
Provider with most accurate pricing for Pitt-Greenville-San Diego flight deals.
Search Deals
Provider most trusted by Cheapflights users for Pitt-Greenville-San Diego flights.
Search Deals
From Pitt-Greenville to San Diego
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Greenville to San Diego that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 6, 2026.
Use the filters below to find and compare flights from Greenville to San Diego that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Thu 7/2

5:10 am-9:00 am

1 stop6h 50m

San Diego

Thu 7/9

10:28 pm-10:35 am

1 stop9h 07m

$477

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Tue 5/19

6:00 am-3:51 pm

2 stops12h 51m

San Diego

Sat 5/23

6:50 am-5:38 pm

1 stop7h 48m

$602

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sun 5/24

5:10 am-12:11 pm

2 stops10h 01m

San Diego

Fri 5/29

7:15 pm-11:58 pm

2 stops25h 43m

$712

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Tue 5/26

5:10 am-9:04 am

1 stop6h 54m

San Diego

Fri 5/29

7:15 pm-11:58 pm

2 stops25h 43m

$730

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Tue 6/2

5:10 am-9:04 am

1 stop6h 54m

San Diego

Thu 6/4

6:50 am-5:38 pm

1 stop7h 48m

$1,062

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Mon 5/25

5:10 am-9:04 am

1 stop6h 54m

San Diego

Fri 5/29

10:28 pm-5:38 pm

1 stop16h 10m

$1,165
Quickest round-trip

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Mon 6/1

5:10 am-9:04 am

1 stop6h 54m

San Diego

Thu 6/4

1:23 pm-11:58 pm

1 stop7h 35m

$1,197
Cheapest one-way
Quickest one-way

GreenvilleSan Diego

PGV - SAN

PGVSAN

Pitt-Greenville

Sun 5/24

5:10 am-9:04 am

1 stop6h 54m

$599

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Sorted by cheapest first

Compare providers for flights from Greenville to San Diego

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Greenville to San Diego in May.
ProviderPrice AccuracyTrust Score*
FlightHubPrice Accuracy3 starsTrust Score*3 stars
ExpediaPrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Greenville, North Carolina-San Diego flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Greenville, North Carolina-San Diego flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Greenville, North Carolina-San Diego flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Greenville, North Carolina-San Diego flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Greenville, North Carolina-San Diego flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Greenville to San Diego

Have a flexible travel schedule? Discover the best time to fly to San Diego from Greenville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Related info for your journey

Find useful and relevant information for your journey from Greenville to San Diego. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Greenville, North Carolina to San Diego?

    A quick flight from Greenville, North Carolina to San Diego can take about 6h 50m. American Airlines provides one of the quickest options available for as low as $477. The distance from Greenville, North Carolina to San Diego is about 2268 mi.

  • Can I find deals for flights from Greenville to San Diego that include hotel bookings?

    Yes. In addition to deals on Greenville to San Diego flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Greenville to San Diego?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Greenville to San Diego.

  • Can I find deals for business class flights from Greenville to San Diego?

    Yes. Cheapflights offers flight deals from Greenville to San Diego by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near San Diego?

Book flights to San Diego if you plan to visit one of these locations
El Cajon
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Julian
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