What are the cheapest airlines flying from Des Moines to Rome round-trip?

Currently priced at $535, United Airlines will fly you from Des Moines to Rome and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from KLM and Delta - these airlines can fly you to your destination from $553 and $558, respectively. These flights start at 50% lower than the current average price 3 months from now.

What are the cheapest airlines to fly from Des Moines to Rome one-way?

For one-way options, check prices for Lufthansa. According to our data, you can fly for as low as $447. Users have also found prices from $542 and $554 on Air Canada and KLM, respectively.

What is the cheapest day to fly from Des Moines to Rome?

Travelers seeking maximum savings on their Des Moines to Rome flight should consider departing on Sunday at noon when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

What are the most popular airlines that fly from Des Moines to Rome?

When booking a flight from Des Moines to Rome, you may want to consider flying on American Airlines, Delta or KLM as they are the most popular for this route.

What is the cheapest day to fly round-trip from Des Moines to Rome?

Flights from Des Moines to Rome are found to be more expensive on Saturday. This shouldn't discourage you from searching as you can still find great deals by being flexible with your options. Use our search form to find deals on tickets to Rome.

What is the cheapest month to fly from Des Moines to Rome?

Our data shows that November tends to be the cheapest month to fly to Rome from Des Moines. Users have commonly found prices around $1,089 for the month, but tickets can be as low as $609. Due to multiple factors, prepare for potentially higher prices in June.

What is the cheapest time of day to fly from DSM to ROM?

It’s optimal to fly from Des Moines to Rome in the afternoon. By choosing this option you can save up to 9% on the cost of your flight, compared to a flight at noon.

Most accurate provider : When it comes to deals on Des Moines-Rome flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.

Most trusted provider : When it comes to deals on Des Moines-Rome flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

What airport do you fly from for flights from Des Moines to Rome?

Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 4 different airlines.

Can I find deals for flights from Des Moines to Rome that include hotel bookings?

Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Des Moines to Rome?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.

Can I find deals for business class flights from Des Moines to Rome?

Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$294+ Flights from Des Moines to Rome - Compare & Save Big

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Cheap flight deals from Des Moines to Rome

Most accurate provider	AranGrant 3 stars
Most trusted provider	AranGrant 3 stars
Round-trip from	$535 (United Airlines)
One-way from	$294 (Kiwi.com)
Popular in	June
Cheapest in	November
Average price	$1,421

Provider with most accurate pricing for Des Moines-Rome (ROM) flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Rome (ROM) flights.

Search Deals

From Des Moines to Rome (ROM)

Search Deals

One-way flight from Des Moines to Rome (ROM)

Search Deals

Highest demand for flights based on searches. 18% potential increase in price ($253 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 4% potential price decrease ($52 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in May 2025

Search Deals

Find flight deals from Des Moines to Rome

Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Wed 10/298:00 amDSM - FCO

2 stops17h 55mUnited Airlines

Wed 11/199:45 amFCO - DSM

1 stop14h 48mUnited Airlines

Deal found 5/22

$558

Wed 10/295:45 amDSM - FCO

1 stop19h 10mKLM

Wed 11/1912:45 pmFCO - DSM

1 stop16h 38mKLM

Deal found 5/22

$592

Wed 8/1310:55 amDSM - FCO

1 stop18h 20mDelta

Fri 8/229:00 amFCO - DSM

1 stop18h 30mDelta

Deal found 5/22

$713

Sat 10/116:09 pmDSM - FCO

1 stop32h 01mBritish Airways

Tue 10/2111:05 amFCO - DSM

1 stop16h 39mBritish Airways

Deal found 5/23

$719

Wed 10/158:00 amDSM - FCO

3 stops18h 15mAir Canada

Fri 10/248:00 amFCO - DSM

3 stops20h 45mAir Canada

Deal found 5/22

$723

Sun 9/2110:03 amDSM - FCO

1 stop16h 07mAmerican Airlines

Sat 10/411:05 amFCO - DSM

1 stop13h 34mAmerican Airlines

Deal found 5/22

$774

Wed 10/2911:30 amDSM - FCO

3 stops38h 25mMultiple Airlines

Wed 11/1912:25 pmFCO - DSM

2 stops16h 11mMultiple Airlines

Deal found 5/22

$840

Wed 10/85:00 amDSM - FCO

2 stops22h 25mAer Lingus

Sat 10/113:10 pmFCO - DSM

2 stops39h 31mAer Lingus

Deal found 5/22

$1,070

Thu 6/196:45 pmDSM - FCO

2 stops21h 55mLufthansa

Sun 7/67:10 amFCO - DSM

2 stops21h 37mLufthansa

Deal found 5/22

$1,400

Best flights from Des Moines to Rome
Discover carefully curated flight deals from Des Moines to Rome that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 23, 2025.

Wed 10/296:00 amDSM - FCO

2 stops22h 55mUnited Airlines

Wed 11/191:15 pmFCO - DSM

3 stops39h 21mUnited Airlines

Deal found 5/21

$535

Wed 10/295:45 amDSM - FCO

1 stop19h 10mKLM

Wed 11/1212:45 pmFCO - DSM

1 stop16h 38mKLM

Deal found 5/21

$553

Wed 10/295:45 amDSM - FCO

2 stops21h 00mDelta

Wed 11/199:20 amFCO - DSM

2 stops18h 30mDelta

Deal found 5/21

$558

Wed 10/298:00 amDSM - FCO

2 stops17h 55mMultiple Airlines

Wed 11/127:05 amFCO - DSM

3 stops21h 31mMultiple Airlines

Deal found 5/20

$625

Tue 7/298:00 amDSM - FCO

2 stops18h 15mAir Canada

Wed 8/2711:30 amFCO - DSM

2 stops30h 09mAir Canada

Deal found 5/21

$690

Sat 10/116:09 pmDSM - FCO

1 stop32h 01mBritish Airways

Tue 10/2111:05 amFCO - DSM

1 stop16h 39mBritish Airways

Deal found 5/21

$719

Sun 9/2110:03 amDSM - FCO

1 stop16h 07mAmerican Airlines

Sat 10/411:05 amFCO - DSM

1 stop13h 34mAmerican Airlines

Deal found 5/22

$774

Wed 9/179:32 amDSM - FCO

2 stops25h 28mFinnair

Mon 9/2210:00 amFCO - DSM

1 stop15h 31mFinnair

Deal found 5/21

$792

Sun 7/68:00 amDSM - FCO

1 stop16h 55mLufthansa

Sun 7/132:20 pmFCO - DSM

1 stop16h 39mLufthansa

Deal found 5/22

$926

Wed 10/87:17 amDSM - FCO

2 stops20h 08mAer Lingus

Sat 10/113:10 pmFCO - DSM

2 stops39h 31mAer Lingus

Deal found 5/21

$1,017

Last-minute flights from Des Moines to Rome
Discover last-minute flight deals from Des Moines to Rome. Data last updated May 23, 2025 and is based on user searches.

Sun 5/2511:53 amDSM - FCO

2 stops24h 57mAer Lingus

Sun 6/87:30 amFCO - DSM

2 stops19h 43mAer Lingus

Deal found 5/22

$1,913

Thu 5/296:30 amDSM - FCO

3 stops20h 55mMultiple Airlines

Sat 5/312:15 pmFCO - DSM

2 stops26h 22mMultiple Airlines

Deal found 5/22

$1,498

Mon 6/25:32 amDSM - FCO

2 stops31h 18mAer Lingus

Thu 6/57:30 amFCO - DSM

2 stops23h 22mAer Lingus

Deal found 5/22

$2,131

Mon 6/211:53 amDSM - FCO

1 stop14h 17mBritish Airways

Thu 6/511:05 amFCO - DSM

1 stop16h 08mBritish Airways

Deal found 5/22

$2,334

Mon 6/28:00 amDSM - FCO

3 stops18h 15mAir Canada

Thu 6/57:10 amFCO - DSM

3 stops22h 35mAir Canada

Deal found 5/22

$2,754

Wed 6/42:20 pmDSM - FCO

1 stop11h 50mBritish Airways

Tue 6/1011:05 amFCO - DSM

1 stop19h 47mBritish Airways

Deal found 5/22

$1,327

Wed 6/48:00 amDSM - FCO

3 stops18h 15mMultiple Airlines

Tue 6/1011:30 amFCO - DSM

2 stops16h 52mMultiple Airlines

Deal found 5/22

$1,485

Fri 6/65:58 pmDSM - FCO

1 stop32h 02mIberia

Sun 6/1511:05 amFCO - DSM

1 stop13h 23mIberia

Deal found 5/22

$7,333

Mon 6/96:07 amDSM - FCO

2 stops21h 48mUnited Airlines

Mon 6/1611:30 amFCO - DSM

2 stops37h 29mUnited Airlines

Deal found 5/22

$905

Mon 6/911:24 amDSM - FCO

2 stops15h 41mDelta

Mon 6/169:45 amFCO - DSM

1 stop20h 18mDelta

Deal found 5/22

$928

Mon 6/97:24 amDSM - FCO

1 stop18h 46mAmerican Airlines

Mon 6/161:10 pmFCO - DSM

1 stop15h 32mAmerican Airlines

Deal found 5/22

$999

Thu 6/125:40 amDSM - FCO

1 stop18h 55mKLM

Thu 6/1911:35 amFCO - DSM

1 stop18h 28mKLM

Deal found 5/22

$1,099

One-way flights from Des Moines to Rome
Search for one-way flight options from Des Moines to Rome. Find affordable one-way fares based on user searches. Data last updated May 23, 2025.

Mon 9/228:00 amDSM - FCO

2 stops32h 35mMultiple Airlines

Deal found 5/21

$294

Wed 9/246:51 pmDSM - FCO

2 stops15h 59mLufthansa

Deal found 5/21

$447

Sun 7/66:50 pmDSM - FCO

2 stops31h 25mAir Canada

Deal found 5/22

$542

Sun 7/65:23 pmDSM - FCO

1 stop12h 22mKLM

Deal found 5/22

$554

Tue 9/2310:03 amDSM - FCO

2 stops17h 22mAer Lingus

Deal found 5/22

$556

Tue 9/236:20 amDSM - FCO

2 stops18h 15mDelta

Deal found 5/22

$558

Wed 9/2411:35 amDSM - FCO

3 stops17h 10mUnited Airlines

Deal found 5/22

$564

Sat 9/206:09 pmDSM - FCO

1 stop32h 01mIberia

Deal found 5/22

$570

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/29

8:00 am-7:55 am

2 stops17h 55m

Rome Fiumicino

Wed 11/19

9:45 am-11:39 pm

2 stops20h 54m

$558

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/29

5:45 am-6:55 am

1 stop19h 10m

Rome Fiumicino

Wed 11/19

12:45 pm-10:23 pm

1 stop16h 38m

$592

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 8/13

10:55 am-12:15 pm

1 stop18h 20m

Rome Fiumicino

Fri 8/22

9:00 am-8:30 pm

1 stop18h 30m

$713

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sat 10/11

6:09 pm-9:10 am

1 stop32h 01m

Rome Fiumicino

Tue 10/21

11:05 am-8:44 pm

1 stop16h 39m

$719

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/15

8:00 am-9:15 am

3 stops18h 15m

Rome Fiumicino

Fri 10/24

8:00 am-9:45 pm

3 stops20h 45m

$723

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Sun 9/21

10:03 am-9:10 am

1 stop16h 07m

Rome Fiumicino

Sat 10/4

11:05 am-5:39 pm

1 stop13h 34m

$774

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/29

11:30 am-7:55 am

3 stops38h 25m

Rome Fiumicino

Wed 11/19

12:25 pm-9:36 pm

2 stops16h 11m

$840

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Wed 10/8

5:00 am-10:25 am

2 stops22h 25m

Rome Fiumicino

Sat 10/11

3:10 pm-11:41 pm

2 stops39h 31m

$1,070

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Thu 6/19

6:45 pm-11:40 pm

2 stops21h 55m

Rome Fiumicino

Sun 7/6

7:10 am-9:47 pm

2 stops21h 37m

$1,400

Des MoinesRome

DSM - FCO

DSMFCO

Des Moines

Fri 6/6

5:58 pm-9:00 am

1 stop32h 02m

Rome Fiumicino

Sun 6/15

11:05 am-5:28 pm

1 stop13h 23m

$7,333

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/21

Showing 1-10 of 18 results

Compare providers for flights from Des Moines to Rome

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in May.

Provider	Price Accuracy	Trust Score*
Expedia	Price Accuracy1 star	Trust Score*3 stars
FlightHub	Price Accuracy3 stars	Trust Score*2 stars
AranGrant	Price Accuracy3 stars	Trust Score*3 stars
eDreams	Price Accuracy3 stars	Trust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

Most accurate provider: When it comes to deals on Des Moines-Rome flights, users find the pricing of AranGrant to be most consistent on Cheapflights vs. AranGrant Users can find the same prices on Des Moines-Rome flight deals on Cheapflights vs. AranGrant >95% of the time. Price accuracy is based on data collected from Des Moines-Rome flight searches over the past month and is updated monthly.
Most trusted provider: When it comes to deals on Des Moines-Rome flights, Cheapflights users trust AranGrant the most. AranGrant has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Des Moines-Rome flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $644). Flying from Des Moines to Rome in June is currently the most expensive (average of $1,164). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Rainfall in Rome by month

In terms of precipitation, rainfall in Rome ranges from 0.6 - 4.4 inches per month. November is typically the wettest month, when rainfall can reach 4.4 in. June is typically the driest time to visit Rome when rainfall is around 0.6 in.

Temperature in Rome by month

If weather is an important factor for your trip to Rome, use this chart to help with planning. For those seeking warmer temperatures, August is the ideal time of year to visit, when temperatures reach an average of 75.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 46.4 F).

Reviews of airlines servicing Rome

See what other customers who have flown with Delta, KLM and Finnair from Des Moines to Rome have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,952 reviews

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

KLM

7.8

Good

1,346 reviews

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Finnair

7.6

Good

1,282 reviews

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,745 reviews

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,952 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What airport do you fly from for flights from Des Moines to Rome?
Located just 3.6 mi from the city center, Des Moines is the airport most travelers will use when flying to Rome from Des Moines. Booking flights from Des Moines (DSM) to Rome should be relatively easy as there are 0 daily outbound flights to Rome from 4 different airlines.
What are the cheapest airlines flying from Des Moines to Rome round-trip?
Currently priced at $535, United Airlines will fly you from Des Moines to Rome and back. In addition to United Airlines, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from KLM and Delta - these airlines can fly you to your destination from $553 and $558, respectively. These flights start at 50% lower than the current average price 3 months from now.
What are the cheapest airlines to fly from Des Moines to Rome one-way?
For one-way options, check prices for Lufthansa. According to our data, you can fly for as low as $447. Users have also found prices from $542 and $554 on Air Canada and KLM, respectively.
Can I find deals for flights from Des Moines to Rome that include hotel bookings?
Yes. In addition to deals on Des Moines to Rome flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Des Moines to Rome?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Des Moines to Rome.
Can I find deals for business class flights from Des Moines to Rome?
Yes. Cheapflights offers flight deals from Des Moines to Rome by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Des Moines to Rome?
Currently, January is the cheapest month in which you can book a flight from Des Moines to Rome (average of $644). Flying from Des Moines to Rome in June is currently the most expensive (average of $1,164). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Des Moines to Rome

Airline	Cheapest	Average	Flexibility	On-time
Delta	Cheapest$641	Average$914	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$663	Average$1,119	FlexibilityNo cancel fee	On-time69%
KLM	Cheapest$668	Average$1,090	FlexibilityNo cancel fee	On-time75%
American Airlines	Cheapest$789	Average$1,171	FlexibilityNo cancel fee	On-time71%

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$294+ Cheap flights from Des Moines (DSM) to Rome (ROM)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/22. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Des Moines to Rome with Cheapflights

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Cheap flight deals from Des Moines to Rome

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Find flight deals from Des Moines to Rome

Cheapest flights from Des Moines to RomeExplore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Des Moines to Rome that are best for you.

Compare providers for flights from Des Moines to Rome

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.

Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Des Moines to Rome in May.

Best time to book a flight from Des Moines to Rome

Have a flexible travel schedule? Discover the best time to fly to Rome from Des Moines with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Des Moines to Rome

What is the cheapest month to book a flight from Des Moines to Rome?

Rainfall in Rome by month

Plan your trip to Rome by taking into account the average rainfall totals by month.

Temperature in Rome by month

Plan your trip to Rome by taking into account the average temperature totals by month.

Reviews of airlines servicing Rome

Get insights into the airlines that provide service to Rome. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Rome. Reviews last updated May 23, 2025.

See what other customers who have flown with Delta, KLM and Finnair from Des Moines to Rome have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Des Moines to Rome. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly from for flights from Des Moines to Rome?

What are the cheapest airlines flying from Des Moines to Rome round-trip?

What are the cheapest airlines to fly from Des Moines to Rome one-way?

Can I find deals for flights from Des Moines to Rome that include hotel bookings?

How can I find direct flights from Des Moines to Rome?

Can I find deals for business class flights from Des Moines to Rome?

What is the cheapest month to book a flight from Des Moines to Rome?

Traveling to a place near Des Moines?

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Alternative routes for Des Moines to Rome

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Top 4 airlines flying from Des Moines to Rome

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Cheapest flights from Des Moines to Rome
Explore the most affordable flight options available from Des Moines to Rome. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 23, 2025.