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$65+ Cheap flights from Missouri to Pennsylvania

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHL
Oct 15 — Oct 221
Wed 10/15
Wed 10/22
1 adult, Economy
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Cheap flight deals from Missouri to Pennsylvania

Keep the following information in mind while searching for Missouri to Pennsylvania flight deals. Data was last updated September 15, 2025.

Round-trip from

$144
(Priceline)

One-way from

$65
(American Airlines)

Popular in

November

Cheapest in

August

Average price

$419

Good round-trip deal

$271 or less

Good one-way deal

$211 or less
From Missouri to Pennsylvania
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One-way flight from Missouri to Pennsylvania
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Highest demand for flights based on searches. 3% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Missouri to Pennsylvania.
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Price to beat on a one-way flight from Missouri to Pennsylvania.
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Find flight deals from Missouri to Pennsylvania

Cheapest flights from Missouri to Pennsylvania
Explore the most affordable flight options available from Missouri to Pennsylvania. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 15, 2025.

This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:00 pmSTL - EWR
1 stop8h 06mFrontier
Sun 10/55:55 amEWR - STL
1 stop10h 09mFrontier
Deal found 9/14$144
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/254:00 pmSTL - EWR
1 stop7h 34mFrontier
Sun 9/285:55 amEWR - STL
1 stop10h 09mFrontier
Deal found 9/14$156
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/187:15 pmSTL - EWR
1 stop12h 45mMultiple Airlines
Thu 10/235:54 amEWR - STL
1 stop5h 43mMultiple Airlines
Deal found 9/14$158
This Cheapflightsfares deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/117:15 pmSTL - EWR
1 stop12h 45mSpirit Airlines
Sat 10/1810:05 amEWR - STL
1 stop9h 05mSpirit Airlines
Deal found 9/13$161
This Orbitz deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:35 amSTL - EWR
1 stop12h 11mMultiple Airlines
Sun 10/55:55 amEWR - STL
1 stop10h 09mMultiple Airlines
Deal found 9/14$164
This Priceline deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/24:00 pmSTL - EWR
1 stop8h 06mFrontier
Mon 10/65:55 amEWR - STL
1 stop10h 09mFrontier
Deal found 9/14$166
This Priceline deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/184:00 pmSTL - EWR
1 stop7h 34mFrontier
Sun 9/215:55 amEWR - STL
1 stop10h 09mFrontier
Deal found 9/13$176
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:24 pmSTL - EWR
Nonstop2h 26mUnited Airlines
Tue 10/1410:00 pmEWR - STL
Nonstop2h 57mUnited Airlines
Deal found 9/12$177
This Mytrip deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:35 amSTL - EWR
1 stop12h 11mSpirit Airlines
Sat 10/46:56 pmEWR - STL
1 stop16h 06mSpirit Airlines
Deal found 9/13$178
This United Airlines deal was found by Cheapflights users on 9/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:00 amSTL - EWR
1 stop4h 27mUnited Airlines
Wed 10/2210:00 pmEWR - STL
Nonstop2h 57mUnited Airlines
Deal found 9/12$183
This Priceline deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/412:20 pmSTL - EWR
1 stop11h 36mSpirit Airlines
Sat 12/67:38 amEWR - STL
1 stop7h 15mSpirit Airlines
Deal found 9/15$185
This Frontier deal was found by Cheapflights users on 9/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1011:32 amSTL - IAD
1 stop10h 57mFrontier
Sat 10/114:22 pmIAD - STL
2 stops18h 00mFrontier
Deal found 9/13$186

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Pennsylvania that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
Use the filters below to find and compare flights from Missouri to Pennsylvania that are best for you.

Fly from

Missouri

Fly to

Pennsylvania

Route

Depart

Return

Price

St. LouisNewark

STL - EWR

STLEWR

Lambert-St Louis

Thu 12/4

12:20 pm-12:56 am

1 stop11h 36m

Newark

Sat 12/6

7:38 am-1:53 pm

1 stop7h 15m

$185

St. LouisNewark

STL - EWR

STLEWR

Lambert-St Louis

Wed 10/8

5:00 am-12:17 pm

1 stop6h 17m

Newark

Tue 10/14

10:00 pm-11:57 pm

Nonstop2h 57m

$187

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Wed 11/12

7:45 pm-12:04 pm

1 stop15h 19m

Washington, D.C. Reagan-National

Mon 11/17

6:00 pm-9:07 am

1 stop16h 07m

$193

St. LouisNewark

STL - EWR

STLEWR

Lambert-St Louis

Wed 10/1

5:28 pm-10:59 pm

1 stop4h 31m

Newark

Sat 10/4

9:50 pm-11:47 pm

Nonstop2h 57m

$195

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Tue 11/11

7:05 am-12:41 pm

1 stop4h 36m

Washington, D.C. Reagan-National

Wed 11/19

6:06 am-9:46 am

1 stop4h 40m

$197

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Sat 11/8

8:43 am-11:55 am

Nonstop2h 12m

Washington, D.C. Reagan-National

Tue 11/11

7:50 am-9:20 am

Nonstop2h 30m

$197

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Mon 11/10

6:09 pm-11:04 pm

1 stop3h 55m

Washington, D.C. Reagan-National

Sun 11/16

6:06 am-9:46 am

1 stop4h 40m

$197

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Mon 11/10

6:09 pm-11:04 pm

1 stop3h 55m

Washington, D.C. Reagan-National

Sat 11/15

8:00 am-12:26 pm

1 stop5h 26m

$197

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Tue 10/14

6:14 pm-10:59 pm

1 stop3h 45m

Washington, D.C. Reagan-National

Wed 10/15

8:59 am-12:35 pm

1 stop4h 36m

$197

St. LouisWashington, D.C.

STL - DCA

STLDCA

Lambert-St Louis

Fri 11/14

6:09 pm-11:04 pm

1 stop3h 55m

Washington, D.C. Reagan-National

Wed 11/19

8:59 am-1:00 pm

1 stop5h 01m

$197

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/14

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Pennsylvania

Have a flexible travel schedule? Discover the best time to fly to Pennsylvania from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Pennsylvania

What is the cheapest month to book a flight from Missouri to Pennsylvania?

Currently, August is the cheapest month in which you can book a flight from Missouri to Pennsylvania (average of $236). Flying from Missouri to Pennsylvania in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to PA?

Find hourly flight availability from Missouri to Pennsylvania. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 15, 2025.

When flying from Missouri to Pennsylvania, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Weekly flight availability from Missouri to Pennsylvania

Explore weekly flight availability from Missouri to Pennsylvania. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 15, 2025.

The most flights from USMO to USPA are scheduled on a Sunday (12 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (8 on average).

Reviews of airlines servicing Pennsylvania

Get insights into the airlines that provide service to Pennsylvania. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Pennsylvania. Reviews last updated September 15, 2025.
See what other customers who have flown with Southwest, Delta, and United Airlines from Missouri to Pennsylvania have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,242 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
8.0
Very good
7,954 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,929 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Frontier
5.8
Fair
3,172 reviews
Southwest
8.0
Very good
4,242 reviews

Comfort

8.0

Overall

8.0

Food

7.0

Boarding

8.1

Crew

8.6

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Missouri to Pennsylvania. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this Missouri to Pennsylvania flight route?

    Flights from Missouri to Pennsylvania have been viewed 16 times in the past calendar month.

  • How long is the flight from Missouri to Pennsylvania?

    Departing from Missouri to Pennsylvania will take you 6h 17m. There are 869 mi between Missouri and Pennsylvania. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Missouri to Pennsylvania one-way?

    The cheapest airlines for a one-way flight from Missouri to Pennsylvania are American Airlines ($66), Frontier ($78), and Southwest ($84).

  • Can I find deals for flights from Missouri to Pennsylvania that include hotel bookings?

    Yes. In addition to deals on Missouri to Pennsylvania flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Pennsylvania?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Pennsylvania.

  • Can I find deals for business class flights from Missouri to Pennsylvania?

    Yes. Cheapflights offers flight deals from Missouri to Pennsylvania by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Pennsylvania?

    Currently, August is the cheapest month in which you can book a flight from Missouri to Pennsylvania (average of $236). Flying from Missouri to Pennsylvania in March is currently the most expensive (average of $295). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Pennsylvania

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to Pennsylvania

Discover the top 6 airlines that operate flights from Missouri to Pennsylvania. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$106Average$227FlexibilityNo cancel feeOn-time65%
FrontierCheapest$119Average$218FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$198Average$467FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$204Average$439FlexibilityNo cancel feeOn-time71%
DeltaCheapest$211Average$379FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$253Average$399FlexibilityNo cancel feeOn-time63%

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