$569+ Cheap flights from Wilmington (ILM) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/25. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Sep 21 — Sep 281
Round-trip
1 adult, Economy
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Best
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Cheapest flights from Wilmington to Panama CityExplore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
Explore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2026.
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:27 pm -
2 stops18h 46m
Tue 11/173:13 pm -
2 stops18h 55m
Deal found 8/18![American Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop7h 16m
Wed 10/72:02 pm -
1 stop8h 57m
Deal found 8/21![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:33 pm -
2 stops18h 29m
Mon 10/122:02 pm -
2 stops21h 30m
Deal found 8/21![American Airlines logo]()
$703
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop7h 16m
Tue 9/151:16 pm -
1 stop9h 35m
Deal found 8/18![American Airlines logo]()
$709
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:20 am -
1 stop7h 39m
Tue 11/173:30 pm -
1 stop7h 32m
Deal found 8/18![Delta logo]()
$725
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:14 pm -
2 stops25h 23m
Tue 9/153:30 pm -
2 stops23h 11m
Deal found 8/18![United Airlines logo]()
$729
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:00 am -
1 stop7h 02m
Sun 11/293:15 pm -
2 stops26h 21m
Deal found 8/21![American Airlines logo]()
$854
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:30 am -
1 stop7h 28m
Mon 10/122:24 pm -
1 stop7h 45m
Deal found 8/21![Delta logo]()
$935
Best flights from Wilmington to Panama CityDiscover carefully curated flight deals from Wilmington to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
Discover carefully curated flight deals from Wilmington to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 22, 2026.
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/37:27 pm -
2 stops18h 46m
Tue 11/173:13 pm -
2 stops18h 55m
Deal found 8/18![American Airlines logo]()
$644
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:20 am -
1 stop7h 39m
Tue 11/173:30 pm -
1 stop7h 32m
Deal found 8/18![Delta logo]()
$725
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:19 pm -
2 stops20h 08m
Sun 2/144:04 pm -
2 stops20h 24m
Deal found 8/22![American Airlines logo]()
$665
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/16:00 am -
1 stop7h 16m
Wed 10/72:02 pm -
1 stop8h 57m
Deal found 8/21![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop7h 16m
Tue 9/151:16 pm -
2 stops20h 20m
Deal found 8/18![American Airlines logo]()
$713
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/56:30 am -
1 stop7h 28m
Mon 10/122:24 pm -
1 stop7h 45m
Deal found 8/21![Delta logo]()
$935
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/57:00 am -
1 stop7h 02m
Mon 10/122:02 pm -
2 stops19h 39m
Deal found 8/21![American Airlines logo]()
$733
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:57 pm -
2 stops19h 05m
Sun 11/293:15 pm -
2 stops26h 21m
Deal found 8/21![American Airlines logo]()
$854
Last-minute flights from Wilmington to Panama CityDiscover last-minute flight deals from Wilmington to Panama City. Data last updated August 22, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Panama City. Data last updated August 22, 2026 and is based on user searches.
This Arangrant deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Arangrant is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:18 pm -
2 stops18h 21m
Thu 8/271:39 pm -
2 stops21h 02m
Deal found 8/21![GOL logo]()
$1,259
This BusinessClass deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am -
1 stop13h 31m
Thu 8/279:45 am -
1 stop13h 12m
Deal found 8/21![Copa Airlines logo]()
$1,578
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:00 am -
1 stop7h 16m
Tue 9/151:16 pm -
1 stop9h 35m
Deal found 8/18![American Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:14 pm -
2 stops25h 23m
Tue 9/153:30 pm -
2 stops23h 11m
Deal found 8/18![United Airlines logo]()
$729
One-way flights from Wilmington to Panama CitySearch for one-way flight options from Wilmington to Panama City. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
Search for one-way flight options from Wilmington to Panama City. Find affordable one-way fares based on user searches. Data last updated August 22, 2026.
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:00 am -
1 stop14h 00m
Deal found 8/19![Delta logo]()
$569
This KAYAK deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/256:02 pm -
2 stops19h 49m
Deal found 8/19![GOL logo]()
$626
This Ovago deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Ovago is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:00 am -
1 stop9h 33m
Deal found 8/17![GOL logo]()
$628
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:10 pm -
3 stops29h 10m
Deal found 8/18![Multiple Airlines logo]()
$723
This Mytrip deal was found by Cheapflights users on 8/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/239:11 am -
3 stops31h 44m
Deal found 8/17![Multiple Airlines logo]()
$868
Find flight deals from Wilmington to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $644 (American Airlines) |
One-way from | $569 (Delta) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
Use the filters below to find and compare flights from Wilmington to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Tue 11/3
7:27 pm-2:13 pm
2 stops18h 46m
Panama City Tocumen Intl
Tue 11/17
3:13 pm-10:08 am
2 stops18h 55m
$644
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Thu 2/4
5:19 pm-1:27 pm
2 stops20h 08m
Panama City Tocumen Intl
Sun 2/14
4:04 pm-12:28 pm
2 stops20h 24m
$665
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Thu 10/1
6:00 am-12:16 pm
1 stop7h 16m
Panama City Tocumen Intl
Wed 10/7
2:02 pm-11:59 pm
1 stop8h 57m
$689
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Fri 9/11
6:00 am-12:16 pm
1 stop7h 16m
Panama City Tocumen Intl
Tue 9/15
1:16 pm-10:36 am
2 stops20h 20m
$713
Quickest round-trip
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Tue 11/3
6:20 am-1:59 pm
1 stop7h 39m
Panama City Tocumen Intl
Tue 11/17
3:30 pm-11:02 pm
1 stop7h 32m
$725
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Mon 10/5
7:00 am-1:02 pm
1 stop7h 02m
Panama City Tocumen Intl
Mon 10/12
2:02 pm-10:41 am
2 stops19h 39m
$733
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Sun 10/25
6:57 pm-1:02 pm
2 stops19h 05m
Panama City Tocumen Intl
Sun 11/29
3:15 pm-5:36 pm
2 stops26h 21m
$854
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Mon 10/5
6:30 am-12:58 pm
1 stop7h 28m
Panama City Tocumen Intl
Mon 10/12
2:24 pm-11:09 pm
1 stop7h 45m
$935
Cheapest one-way
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Fri 12/25
6:00 am-8:00 pm
1 stop14h 00m
$569
Quickest one-way
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Wed 12/23
6:00 am-3:33 pm
1 stop9h 33m
$628
Showing 1-10 of 13 resultsSorted by cheapest first
- Most accurate provider: When it comes to deals on Wilmington-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Wilmington with our price prediction graph.
ILM-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 22, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Entertainment
6.8
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Food
6.4
Entertainment
6.8
Overall
7.1
Boarding
7.5
Comfort
7.2
Crew
7.9
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from Wilmington to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Wilmington and Panama City flights
Browse other Wilmington and Panama City flight options. Last updated on August 22, 2026.
Other flights from Wilmington
Browse through other flights departing from Wilmington. Flights are based on user searches made on Cheapflights and were last updated on August 22, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Wilmington to Panama City
Discover the top airline that operate flights from Wilmington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$495 | Average$605 | FlexibilityNo cancel fee | On-time71% |