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Panama City

$527+ Cheap flights from Wilmington (ILM) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/18. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
May 18 — May 251
Mon 5/18
Mon 5/25
1 adult, Economy
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Cheap flight deals from Wilmington to Panama City

Cheapest flights from Wilmington to Panama City
Explore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 18, 2026.

This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
ILM
-
PTY
1 stop9h 10m
American Airlines
Wed 9/233:40 pm
PTY
-
ILM
1 stop6h 38m
American Airlines
Deal found 4/14$527
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/224:09 pm
ILM
-
PTY
2 stops47h 05m
United Airlines
Wed 8/2610:00 am
PTY
-
ILM
2 stops28h 28m
United Airlines
Deal found 4/15$539
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/96:00 am
ILM
-
PTY
1 stop9h 10m
American Airlines
Mon 9/143:40 pm
PTY
-
ILM
2 stops19h 34m
American Airlines
Deal found 4/16$561
This BusinessClass deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:11 pm
ILM
-
PTY
1 stop11h 53m
Multiple Airlines
Tue 5/59:45 am
PTY
-
ILM
1 stop12h 59m
Multiple Airlines
Deal found 4/13$580
This Delta deal was found by Cheapflights users on 4/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/266:00 am
ILM
-
PTY
1 stop7h 56m
Delta
Sat 10/32:21 pm
PTY
-
ILM
1 stop7h 48m
Delta
Deal found 4/17$587
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/264:07 pm
ILM
-
PTY
2 stops23h 03m
American Airlines
Sat 10/33:40 pm
PTY
-
ILM
2 stops17h 39m
American Airlines
Deal found 4/14$591
This American Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:12 pm
ILM
-
PTY
2 stops20h 34m
American Airlines
Tue 5/51:49 pm
PTY
-
ILM
2 stops17h 42m
American Airlines
Deal found 4/13$611
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
ILM
-
PTY
1 stop7h 46m
American Airlines
Sat 5/161:49 pm
PTY
-
ILM
1 stop9h 08m
American Airlines
Deal found 4/14$647
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:00 am
ILM
-
PTY
1 stop7h 14m
American Airlines
Wed 6/101:14 pm
PTY
-
ILM
1 stop10h 10m
American Airlines
Deal found 4/16$667

Find flight deals from Wilmington to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 18, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$527
(American Airlines)

Popular in

June

Cheapest in

August

Average price

$560
Provider with most accurate pricing for Wilmington New Hanover County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Panama City Tocumen Intl flights.
Search Deals
From Wilmington New Hanover County to Panama City Tocumen Intl
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
Use the filters below to find and compare flights from Wilmington to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 8/22

4:09 pm-2:14 pm

2 stops47h 05m

Panama City Tocumen Intl

Wed 8/26

3:30 pm-3:28 pm

2 stops22h 58m

$539

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 4/28

5:11 pm-4:04 am

1 stop11h 53m

Panama City Tocumen Intl

Tue 5/5

9:45 am-11:44 pm

1 stop12h 59m

$580

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Wed 6/3

4:05 pm-4:12 pm

2 stops25h 07m

Panama City Tocumen Intl

Wed 6/10

3:30 pm-3:24 pm

2 stops22h 54m

$580
Quickest round-trip

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 9/26

6:00 am-12:56 pm

1 stop7h 56m

Panama City Tocumen Intl

Sat 10/3

2:21 pm-11:09 pm

1 stop7h 48m

$587

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 5/10

6:00 am-12:46 pm

1 stop7h 46m

Panama City Tocumen Intl

Sat 5/16

1:49 pm-11:57 pm

1 stop9h 08m

$647

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/14

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Wilmington-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Wilmington to Panama City

How much does it cost to fly round-trip from Wilmington to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 18, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,604 reviews

Boarding

7.5

Overall

7.1

Food

6.4

Entertainment

6.9

Crew

7.9

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,604 reviews
American Airlines
7.1
Good
11,604 reviews

Boarding

7.5

Overall

7.1

Food

6.4

Entertainment

6.9

Crew

7.9

Comfort

7.2

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Panama City?

    For as low as $539, United Airlines can have you in Panama City from Wilmington in 47h 05m. The distance between Wilmington and Panama City is about 1742 mi.

  • What is the cheapest airline to fly from Wilmington to Panama City round-trip?

    American Airlines, at $491, was found to be the cheapest airline from Wilmington to Panama City.. American Airlines is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Panama City that include hotel bookings?

    Yes. In addition to deals on Wilmington to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Panama City.

  • Can I find deals for business class flights from Wilmington to Panama City?

    Yes. Cheapflights offers flight deals from Wilmington to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Wilmington to Panama City

Discover the top airline that operate flights from Wilmington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 18, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$491Average$615FlexibilityNo cancel feeOn-time71%

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