HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$509+ Cheap flights from Wilmington (ILM) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/22. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Apr 22 — Apr 291
Wed 4/22
Wed 4/29
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Wilmington to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Wilmington to Panama City

Cheapest flights from Wilmington to Panama City
Explore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 23, 2026.

This KAYAK deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am
ILM
-
PTY
1 stop13h 01m
Multiple Airlines
Mon 10/269:30 am
PTY
-
ILM
1 stop13h 23m
Multiple Airlines
Deal found 3/19$509
This KAYAK deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:30 am
ILM
-
PTY
1 stop13h 01m
Multiple Airlines
Wed 10/289:30 am
PTY
-
ILM
1 stop13h 23m
Multiple Airlines
Deal found 3/19$513
This KAYAK deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:30 am
ILM
-
PTY
1 stop13h 01m
Multiple Airlines
Tue 10/279:30 am
PTY
-
ILM
1 stop28h 58m
Multiple Airlines
Deal found 3/19$516
This Gurufare deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gurufare is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:30 am
ILM
-
PTY
1 stop13h 01m
Copa Airlines
Tue 10/279:30 am
PTY
-
ILM
1 stop28h 58m
Copa Airlines
Deal found 3/19$518
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/164:05 pm
ILM
-
PTY
2 stops25h 07m
United Airlines
Wed 7/83:30 pm
PTY
-
ILM
2 stops22h 54m
United Airlines
Deal found 3/21$531
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/304:05 pm
ILM
-
PTY
2 stops25h 07m
United Airlines
Sat 6/63:30 pm
PTY
-
ILM
2 stops22h 54m
United Airlines
Deal found 3/20$539
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:28 pm
ILM
-
PTY
2 stops18h 32m
American Airlines
Tue 10/273:35 pm
PTY
-
ILM
2 stops17h 45m
American Airlines
Deal found 3/19$561
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2410:20 am
ILM
-
PTY
1 stop27h 36m
Delta
Wed 10/282:21 pm
PTY
-
ILM
1 stop7h 43m
Delta
Deal found 3/19$565
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:00 am
ILM
-
PTY
2 stops8h 46m
American Airlines
Sat 5/161:49 pm
PTY
-
ILM
2 stops21h 46m
American Airlines
Deal found 3/19$591

Find flight deals from Wilmington to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$531
(United Airlines)

Popular in

June

Cheapest in

August

Average price

$647
Provider with most accurate pricing for Wilmington New Hanover County-Panama City Tocumen Intl flight deals.
Search Deals
Provider most trusted by Cheapflights users for Wilmington New Hanover County-Panama City Tocumen Intl flights.
Search Deals
From Wilmington New Hanover County to Panama City Tocumen Intl
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Wilmington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
Use the filters below to find and compare flights from Wilmington to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Tue 6/16

4:05 pm-4:12 pm

2 stops25h 07m

Panama City Tocumen Intl

Wed 7/8

3:30 pm-3:24 pm

2 stops22h 54m

$531

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sat 5/30

4:05 pm-4:12 pm

2 stops25h 07m

Panama City Tocumen Intl

Sat 6/6

3:30 pm-3:24 pm

2 stops22h 54m

$539
Quickest round-trip

WilmingtonPanama City

ILM - PTY

ILMPTY

Wilmington New Hanover County

Sun 5/10

5:00 am-12:46 pm

2 stops8h 46m

Panama City Tocumen Intl

Sat 5/16

1:49 pm-9:46 am

2 stops18h 57m

$591

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/21

Sorted by cheapest first
  • Most accurate provider: When it comes to deals on Wilmington-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Wilmington-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Wilmington to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Wilmington with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated March 23, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,488 reviews

Boarding

7.5

Crew

7.9

Overall

7.1

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes
American Airlines
7.1
Good
11,488 reviews
American Airlines
7.1
Good
11,488 reviews

Boarding

7.5

Crew

7.9

Overall

7.1

Food

6.4

Entertainment

6.9

Comfort

7.2

Reviews

1 / 20
2.0
Mediocre

Anonymous,Mar 2026

MIA - SFO

Horrible. When they power flights for other airlines there is nothing they can do to change or accommodate any changes

Related info for your journey

Find useful and relevant information for your journey from Wilmington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Wilmington to Panama City?

    For as low as $591, United Airlines can have you in Panama City from Wilmington in 8h 46m. The distance between Wilmington and Panama City is about 1742 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Wilmington to Panama City round-trip?

    American Airlines, at $491, was found to be the cheapest airline from Wilmington to Panama City.. American Airlines is currently priced 24% below the average price you’ll pay for this route.

  • Can I find deals for flights from Wilmington to Panama City that include hotel bookings?

    Yes. In addition to deals on Wilmington to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Wilmington to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Wilmington to Panama City.

  • Can I find deals for business class flights from Wilmington to Panama City?

    Yes. Cheapflights offers flight deals from Wilmington to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Top airline flying from Wilmington to Panama City

Discover the top airline that operate flights from Wilmington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$491Average$615FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.