$685+ Cheap flights from Wilmington (ILM) to Panama City (PTY)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
ILM — PTY
Oct 21 — Oct 281
Round-trip
1 adult, Economy
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Find cheap flights from Wilmington to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Wilmington to Panama City
Cheapest
Best
Last-minute
Cheapest flights from Wilmington to Panama CityExplore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
Explore the most affordable flight options available from Wilmington to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/44:49 pm -
2 stops21h 24m
Wed 11/113:13 pm -
2 stops20h 25m
Deal found 9/20![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 16m
Tue 10/132:02 pm -
1 stop8h 57m
Deal found 9/17![American Airlines logo]()
$739
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/812:46 pm -
2 stops25h 27m
Sun 11/223:34 pm -
2 stops22h 18m
Deal found 9/18![American Airlines logo]()
$753
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 16m
Sun 9/271:16 pm -
2 stops20h 20m
Deal found 9/20![American Airlines logo]()
$787
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:20 am -
1 stop7h 39m
Wed 11/113:29 pm -
1 stop7h 33m
Deal found 9/20![Delta logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:02 pm -
2 stops21h 31m
Tue 1/124:55 pm -
2 stops17h 08m
Deal found 9/19![American Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:26 pm -
2 stops20h 47m
Mon 11/303:34 pm -
1 stop8h 25m
Deal found 9/17![American Airlines logo]()
$828
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop8h 13m
Sat 12/264:33 pm -
1 stop7h 53m
Deal found 9/19![American Airlines logo]()
$844
Best flights from Wilmington to Panama CityDiscover carefully curated flight deals from Wilmington to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
Discover carefully curated flight deals from Wilmington to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 21, 2026.
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/118:02 pm -
1 stop19h 18m
Mon 3/153:13 pm -
1 stop7h 46m
Deal found 9/19![American Airlines logo]()
$685
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:20 am -
1 stop7h 39m
Wed 11/113:29 pm -
1 stop7h 33m
Deal found 9/20![Delta logo]()
$819
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 16m
Tue 10/132:02 pm -
2 stops21h 13m
Deal found 9/17![American Airlines logo]()
$743
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/296:02 pm -
2 stops21h 31m
Tue 1/124:55 pm -
2 stops17h 08m
Deal found 9/19![American Airlines logo]()
$823
This American Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/175:26 pm -
2 stops20h 47m
Mon 11/303:34 pm -
1 stop8h 25m
Deal found 9/18![American Airlines logo]()
$828
This American Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop8h 13m
Sat 12/264:33 pm -
1 stop7h 53m
Deal found 9/19![American Airlines logo]()
$844
Last-minute flights from Wilmington to Panama CityDiscover last-minute flight deals from Wilmington to Panama City. Data last updated September 21, 2026 and is based on user searches.
Discover last-minute flight deals from Wilmington to Panama City. Data last updated September 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/256:00 am -
1 stop7h 16m
Sun 9/271:16 pm -
2 stops20h 20m
Deal found 9/20![American Airlines logo]()
$787
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:00 am -
1 stop7h 16m
Tue 10/132:02 pm -
1 stop8h 57m
Deal found 9/17![American Airlines logo]()
$739
Find flight deals from Wilmington to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Wilmington (ILM) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $685 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Wilmington to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
Use the filters below to find and compare flights from Wilmington to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Thu 3/11
8:02 pm-3:20 pm
1 stop19h 18m
Panama City Tocumen Intl
Mon 3/15
3:13 pm-11:59 pm
1 stop7h 46m
$685
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Fri 10/2
6:00 am-12:16 pm
1 stop7h 16m
Panama City Tocumen Intl
Tue 10/13
2:02 pm-12:15 pm
2 stops21h 13m
$743
Quickest round-trip
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Wed 11/4
6:20 am-1:59 pm
1 stop7h 39m
Panama City Tocumen Intl
Wed 11/11
3:29 pm-11:02 pm
1 stop7h 33m
$819
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Tue 12/29
6:02 pm-3:33 pm
2 stops21h 31m
Panama City Tocumen Intl
Tue 1/12
4:55 pm-10:03 am
2 stops17h 08m
$823
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Tue 11/17
5:26 pm-2:13 pm
2 stops20h 47m
Panama City Tocumen Intl
Mon 11/30
3:34 pm-11:59 pm
1 stop8h 25m
$828
WilmingtonPanama City
ILM Wilmington New Hanover County - PTY Panama City Tocumen Intl
ILMPTY
Wilmington New Hanover County
Fri 12/4
6:00 am-2:13 pm
1 stop8h 13m
Panama City Tocumen Intl
Sat 12/26
4:33 pm-12:26 am
1 stop7h 53m
$844
Sorted by cheapest first
- Most accurate provider: When it comes to deals on Wilmington-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Wilmington-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Wilmington-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Wilmington-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Wilmington-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Wilmington to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Wilmington with our price prediction graph.
ILM-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 21, 2026.
Read reviews from past customers who have flown American Airlines from Wilmington to Panama City. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.2
Overall
7.0
Entertainment
6.8
Boarding
7.4
Crew
7.9
Food
6.4
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Comfort
7.2
Overall
7.0
Entertainment
6.8
Boarding
7.4
Crew
7.9
Food
6.4
Reviews
1 / 20
2.0
MediocreSusie,Jan 2026
CLT - TPA
Related info for your journey
Find useful and relevant information for your journey from Wilmington to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
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Wilmington and Panama City flights
Browse other Wilmington and Panama City flight options. Last updated on September 21, 2026.
Other flights from Wilmington
Browse through other flights departing from Wilmington. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Wilmington to Panama City
Discover the top airline that operate flights from Wilmington to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$495 | Average$605 | FlexibilityNo cancel fee | On-time71% |