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Panama City

$155+ Cheap flights from Spartanburg, SC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Nov 26 — Dec 31
Wed 11/26
Wed 12/3
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Panama City Tocumen Intl are usually found in September or May, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Spartanburg to Panama City

Keep the following information in mind while searching for Spartanburg to Panama City flight deals. Data was last updated October 27, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$372
(Avianca Connect)

One-way from

$155
(Avianca Connect)

Popular in

December

Cheapest in

September

Average price

$546
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
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From Spartanburg to Panama City Tocumen Intl
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One-way flight from Spartanburg to Panama City Tocumen Intl
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Highest demand for flights based on searches. 12% potential increase in price ($80 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Spartanburg to Panama City

Cheapest flights from Spartanburg to Panama City
Explore the most affordable flight options available from Spartanburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 27, 2025.

This Avianca Connect deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/187:59 pmCLT - PTY
2 stops18h 01mMultiple Airlines
Sun 11/232:55 pmPTY - CLT
2 stops17h 54mMultiple Airlines
Deal found 10/27$372
This Avianca Connect deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:38 pmCLT - PTY
2 stops16h 22mMultiple Airlines
Tue 11/185:50 pmPTY - CLT
2 stops19h 10mMultiple Airlines
Deal found 10/26$373
This Avianca Connect deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/149:38 pmCLT - PTY
2 stops16h 22mMultiple Airlines
Tue 11/182:55 pmPTY - CLT
2 stops22h 05mMultiple Airlines
Deal found 10/25$379
This Avianca Connect deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca Connect is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/159:57 pmCLT - PTY
2 stops10h 53mMultiple Airlines
Tue 11/185:50 pmPTY - CLT
2 stops19h 10mMultiple Airlines
Deal found 10/27$380
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/76:33 amCLT - PTY
1 stop7h 48mDelta
Thu 12/113:46 pmPTY - CLT
1 stop17h 02mDelta
Deal found 10/27$400
This American Airlines deal was found by Cheapflights users on 10/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/195:15 amCLT - PTY
1 stop8h 34mAmerican Airlines
Sun 11/232:43 pmPTY - CLT
1 stop17h 07mAmerican Airlines
Deal found 10/25$405
This Kiwi.com deal was found by Cheapflights users on 10/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/210:41 pmCLT - PTY
1 stop9h 25mMultiple Airlines
Sat 11/89:43 pmPTY - CLT
1 stop10h 04mMultiple Airlines
Deal found 10/26$426

Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
Use the filters below to find and compare flights from Spartanburg to Panama City that are best for you.

Fly from

Spartanburg

Fly to

Panama City

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 11/14

9:38 pm-2:00 pm

2 stops16h 22m

Panama City Tocumen Intl

Tue 11/18

2:55 pm-1:00 pm

2 stops22h 05m

$373

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 11/15

9:57 pm-2:00 pm

2 stops16h 03m

Panama City Tocumen Intl

Tue 11/18

2:55 pm-1:00 pm

2 stops22h 05m

$379

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 11/18

7:57 am-2:12 pm

1 stop6h 15m

Panama City Tocumen Intl

Sun 11/23

8:05 am-11:50 pm

1 stop15h 45m

$400

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/15

7:55 am-3:42 pm

1 stop7h 47m

Panama City Tocumen Intl

Thu 12/18

4:55 pm-11:59 pm

1 stop7h 04m

$400

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 12/7

6:33 am-2:21 pm

1 stop7h 48m

Panama City Tocumen Intl

Tue 12/9

3:46 pm-11:42 pm

1 stop7h 56m

$400

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 12/7

6:33 am-2:21 pm

1 stop7h 48m

Panama City Tocumen Intl

Wed 12/10

3:46 pm-8:48 am

1 stop17h 02m

$400

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/8

7:18 pm-2:21 pm

1 stop19h 03m

Panama City Tocumen Intl

Thu 12/11

3:46 pm-11:42 pm

1 stop7h 56m

$406

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 11/19

7:59 pm-2:00 pm

2 stops18h 01m

Panama City Tocumen Intl

Sun 11/23

5:50 pm-8:49 am

2 stops14h 59m

$428

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 12/1

5:15 am-1:43 pm

1 stop8h 28m

Panama City Tocumen Intl

Thu 12/4

2:50 pm-10:57 pm

1 stop8h 07m

$440

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 11/27

8:52 pm-8:50 am

2 stops11h 58m

$155

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/26

Showing 1-10 of 18 results
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Best time to book a flight from Spartanburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Panama City

How far ahead should I book a flight from Spartanburg to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Panama City. Price data was last updated on October 24, 2025.

The best time to book flights from Spartanburg to Panama City is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Spartanburg to Panama City?

Currently, November is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $228). Flying from Spartanburg to Panama City in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to PTY?

Find hourly flight availability from Spartanburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 27, 2025.

A simple way to save on the total cost of your ticket is to fly from Spartanburg to Panama City at noon. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the afternoon.

How much does it cost to fly round-trip from Spartanburg to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 27, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Spartanburg to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
United Airlines
7.4
Good
8,997 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,033 reviews
Delta
7.9
Good
7,996 reviews

Food

7.3

Comfort

7.9

Entertainment

7.9

Overall

7.9

Boarding

8.2

Crew

8.5

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spartanburg?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Spartanburg to Panama City. You should not have trouble finding flights to Tocumen Intl from Spartanburg; the airport handles an average of 0 inbound flights from Spartanburg per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Spartanburg. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • How long is the flight from Spartanburg to Panama City?

    Airlines like Delta fly from Spartanburg to Panama City in about 6h 15m. The time it takes to get you to your destination can typically vary by up to . There are 1808 mi between Spartanburg and Panama City.

  • Can I find deals for flights from Spartanburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Panama City.

  • Can I find deals for business class flights from Spartanburg to Panama City?

    Yes. Cheapflights offers flight deals from Spartanburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $228). Flying from Spartanburg to Panama City in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Spartanburg to Panama City

Discover the top 3 airlines that operate flights from Spartanburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 27, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$352Average$467FlexibilityNo cancel feeOn-time69%
DeltaCheapest$371Average$561FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$383Average$572FlexibilityNo cancel feeOn-time71%

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