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Panama City

$203+ Cheap flights from Spartanburg, SC to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/20. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — PTY
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheapflights Tip: The best prices from Spartanburg to Panama City Tocumen Intl are usually found in September or May, booked 21 days in advance, depart on a Wednesday or Tuesday and return on a Wednesday

Cheap flight deals from Spartanburg to Panama City

Cheapest flights from Spartanburg to Panama City
Explore the most affordable flight options available from Spartanburg to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/186:22 amCLT - PTY
1 stop13h 16mUnited Airlines
Thu 12/2511:35 amPTY - CLT
1 stop10h 07mUnited Airlines
Deal found 12/17$586
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/276:22 amCLT - PTY
1 stop13h 16mUnited Airlines
Tue 1/610:00 amPTY - CLT
1 stop11h 16mUnited Airlines
Deal found 12/17$678
This Delta deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/1911:38 amCLT - PTY
1 stop8h 21mDelta
Tue 12/238:00 amPTY - CLT
1 stop10h 13mDelta
Deal found 12/16$687
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/169:45 pmCLT - PTY
1 stop16h 02mAmerican Airlines
Mon 12/222:53 pmPTY - CLT
1 stop17h 18mAmerican Airlines
Deal found 12/15$713
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/3010:45 pmCLT - PTY
1 stop15h 08mAmerican Airlines
Tue 1/64:31 pmPTY - CLT
1 stop16h 48mAmerican Airlines
Deal found 12/16$743
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/269:34 pmCLT - PTY
3 stops21h 21mMultiple Airlines
Tue 12/3011:25 amPTY - CLT
3 stops32h 44mMultiple Airlines
Deal found 12/17$748
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/2611:24 amCLT - PTY
1 stop27h 21mUnited Airlines
Tue 12/304:41 pmPTY - CLT
1 stop29h 01mUnited Airlines
Deal found 12/16$794
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/267:11 amCLT - PTY
1 stop6h 42mAmerican Airlines
Tue 12/304:55 pmPTY - CLT
1 stop15h 16mAmerican Airlines
Deal found 12/17$795

Find flight deals from Spartanburg to Panama City

Keep the following information in mind while searching for Spartanburg to Panama City flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$428
(Avianca Connect)

One-way from

$203
(Avianca Connect)

Popular in

December

Cheapest in

September

Average price

$727
Provider with most accurate pricing for Charlotte Douglas-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Charlotte Douglas-Panama City Tocumen Intl flights.
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From Spartanburg to Panama City Tocumen Intl
Search Deals
One-way flight from Spartanburg to Panama City Tocumen Intl
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($77 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Spartanburg to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Spartanburg to Panama City that are best for you.

Fly from

Spartanburg

Fly to

Panama City

Route

Depart

Return

Price

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Fri 1/30

7:00 am-12:40 am

2 stops17h 40m

Panama City Tocumen Intl

Fri 2/6

2:55 pm-12:22 pm

2 stops21h 27m

$444

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 2/15

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Thu 2/19

5:50 pm-12:20 pm

2 stops18h 30m

$463

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Tue 4/14

5:30 am-12:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Wed 4/22

2:20 pm-8:38 am

1 stop17h 18m

$468

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 4/16

6:23 am-4:12 pm

1 stop10h 49m

Panama City Tocumen Intl

Wed 4/22

10:00 am-9:40 pm

1 stop10h 40m

$468

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Wed 4/15

5:30 am-12:55 pm

1 stop8h 25m

Panama City Tocumen Intl

Tue 4/28

2:20 pm-8:38 am

1 stop17h 18m

$468

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 2/1

7:00 am-1:00 am

2 stops18h 00m

Panama City Tocumen Intl

Sun 2/8

2:55 pm-12:22 pm

2 stops21h 27m

$470

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sun 2/15

4:50 pm-5:07 pm

1 stop24h 17m

Panama City Tocumen Intl

Thu 2/19

4:41 pm-10:47 am

1 stop18h 06m

$477

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Sat 5/9

6:30 am-4:12 pm

1 stop10h 42m

Panama City Tocumen Intl

Mon 5/11

10:00 am-9:52 pm

1 stop10h 52m

$488

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Thu 2/26

6:33 am-7:38 pm

1 stop13h 05m

Panama City Tocumen Intl

Sun 3/1

4:41 pm-10:47 am

1 stop18h 06m

$488

CharlottePanama City

CLT - PTY

CLTPTY

Charlotte Douglas

Mon 4/20

6:23 am-2:14 pm

1 stop8h 51m

Panama City Tocumen Intl

Sun 4/26

9:45 am-9:07 pm

1 stop10h 22m

$488

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/16

Showing 1-10 of 16 results
1
2

Best time to book a flight from Spartanburg to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Spartanburg with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Spartanburg to Panama City

How far ahead should I book a flight from Spartanburg to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Spartanburg to Panama City. Price data was last updated on December 12, 2025.

The best time to book flights from Spartanburg to Panama City is 21 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Spartanburg to Panama City?

Currently, August is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $267). Flying from Spartanburg to Panama City in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SB1 to PTY?

Find hourly flight availability from Spartanburg to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

A simple way to save on the total cost of your ticket is to fly from Spartanburg to Panama City at noon. If you’re flexible enough to do this you can expect to save up to 7% on your trip compared to booking a flight in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated December 18, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and American Airlines from Spartanburg to Panama City by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,005 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,091 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,054 reviews
Delta
7.9
Good
8,005 reviews

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Comfort

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Spartanburg to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from Spartanburg?

    Panama City Tocumen Intl (PTY) is the airport you will fly into if you book a flight from Spartanburg to Panama City. You should not have trouble finding flights to Tocumen Intl from Spartanburg; the airport handles an average of 0 inbound flights from Spartanburg per day. You should also have plenty of airline options to choose from since 3 airlines have flights to the Panama City airport from Spartanburg. It is only a 11.4 mi journey from Tocumen Intl (PTY) to Panama City’s city center.

  • How long is the flight from Spartanburg to Panama City?

    Airlines like Delta and United Airlines fly from Spartanburg to Panama City in about 8h 25m. The time it takes to get you to your destination can typically vary by up to 2h 24m. There are 1808 mi between Spartanburg and Panama City. This flight may include one or multiple stops.

  • Can I find deals for flights from Spartanburg to Panama City that include hotel bookings?

    Yes. In addition to deals on Spartanburg to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Spartanburg to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Spartanburg to Panama City.

  • Can I find deals for business class flights from Spartanburg to Panama City?

    Yes. Cheapflights offers flight deals from Spartanburg to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Spartanburg to Panama City?

    Currently, August is the cheapest month in which you can book a flight from Spartanburg to Panama City (average of $267). Flying from Spartanburg to Panama City in January is currently the most expensive (average of $435). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Spartanburg to Panama City

Discover the top 3 airlines that operate flights from Spartanburg to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$353Average$574FlexibilityNo cancel feeOn-time71%
DeltaCheapest$371Average$546FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$383Average$470FlexibilityNo cancel feeOn-time69%

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