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Panama City

$194+ Cheap flights from San Diego (SAN) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/26. Fares are subject to change and may not be available on all flights or dates of travel.
SAN — PTY
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheapflights Tip: The best prices from San Diego to Panama City Tocumen Intl are usually found in September or August, booked 88 days in advance, depart on a Tuesday or Thursday and return on a Tuesday

Cheap flight deals from San Diego to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from San Diego (SAN) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 17, 2025.

Round-trip from

$439
(Copa Airlines)

One-way from

$194
(United Airlines)

Popular in

December

Cheapest in

September

Average price

$388

Good round-trip deal

$413 or less

Good one-way deal

$199 or less
From San Diego to Panama City Tocumen Intl
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One-way flight from San Diego to Panama City Tocumen Intl
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Highest demand for flights based on searches. 15% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from San Diego to Panama City Tocumen Intl.
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Price to beat on a one-way flight from San Diego to Panama City Tocumen Intl.
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Find flight deals from San Diego to Panama City

Cheapest flights from San Diego to Panama City
Explore the most affordable flight options available from San Diego to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Copa Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/78:10 pmSAN - PTY
Nonstop6h 10mCopa Airlines
Sun 11/161:15 pmPTY - SAN
Nonstop6h 48mCopa Airlines
Deal found 9/16$439
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:50 pmSAN - PTY
1 stop19h 59mUnited Airlines
Sun 11/163:35 pmPTY - SAN
1 stop11h 38mUnited Airlines
Deal found 9/17$453
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/75:50 pmSAN - PTY
1 stop17h 55mUnited Airlines
Sat 11/228:55 amPTY - SAN
2 stops16h 34mUnited Airlines
Deal found 9/17$458
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/89:54 pmSAN - PTY
2 stops12h 55mAmerican Airlines
Sat 11/222:43 pmPTY - SAN
1 stop23h 44mAmerican Airlines
Deal found 9/16$471
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/85:55 pmSAN - PTY
3 stops41h 50mUnited Airlines
Sat 11/228:55 amPTY - SAN
2 stops16h 34mUnited Airlines
Deal found 9/17$480
This Delta deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2910:30 pmSAN - PTY
1 stop12h 26mDelta
Fri 11/73:21 pmPTY - SAN
1 stop10h 53mDelta
Deal found 9/16$488
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/2710:45 pmSAN - PTY
1 stop13h 18mAmerican Airlines
Mon 11/102:49 pmPTY - SAN
2 stops23h 29mAmerican Airlines
Deal found 9/15$493
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3012:30 pmSAN - PTY
1 stop23h 33mAmerican Airlines
Thu 11/62:49 pmPTY - SAN
1 stop11h 18mAmerican Airlines
Deal found 9/15$503
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3112:30 pmSAN - PTY
1 stop23h 33mAmerican Airlines
Fri 11/72:49 pmPTY - SAN
2 stops22h 07mAmerican Airlines
Deal found 9/16$508
This Copa Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/139:12 pmSAN - PTY
Nonstop6h 13mCopa Airlines
Mon 10/201:15 pmPTY - SAN
Nonstop6h 42mCopa Airlines
Deal found 9/15$509

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Diego to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from San Diego to Panama City that are best for you.

Fly from

San Diego

Fly to

Panama City

Route

Depart

Return

Price

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/7

8:10 pm-5:20 am

Nonstop6h 10m

Panama City Tocumen Intl

Sun 11/16

1:15 pm-5:03 pm

Nonstop6h 48m

$439

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 11/7

7:50 pm-6:49 pm

1 stop19h 59m

Panama City Tocumen Intl

Sun 11/16

3:35 pm-12:13 am

1 stop11h 38m

$453

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 11/12

5:50 pm-2:45 pm

1 stop17h 55m

Panama City Tocumen Intl

Sat 11/15

8:55 am-6:24 pm

1 stop12h 29m

$453

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 10/31

4:10 pm-1:45 pm

2 stops19h 35m

Panama City Tocumen Intl

Fri 11/7

8:55 am-9:53 pm

1 stop15h 58m

$493

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 10/23

10:30 pm-12:56 pm

1 stop12h 26m

Panama City Tocumen Intl

Mon 10/27

2:21 pm-11:14 pm

1 stop10h 53m

$523

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Tue 10/14

7:28 pm-2:14 pm

2 stops16h 46m

Panama City Tocumen Intl

Tue 10/21

3:35 pm-12:15 am

1 stop10h 40m

$523

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Thu 10/16

10:45 pm-2:03 pm

1 stop13h 18m

Panama City Tocumen Intl

Wed 10/29

3:15 pm-9:12 am

2 stops19h 57m

$528

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Fri 10/17

7:28 pm-2:14 pm

2 stops16h 46m

Panama City Tocumen Intl

Fri 10/24

10:00 am-7:52 pm

2 stops11h 52m

$528

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Mon 10/13

6:15 am-6:37 pm

1 stop10h 22m

Panama City Tocumen Intl

Mon 10/20

3:35 pm-12:15 am

1 stop10h 40m

$548

San DiegoPanama City

SAN - PTY

SANPTY

San Diego

Wed 11/26

8:00 am-7:38 pm

1 stop8h 38m

$194

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 15 results
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Best time to book a flight from San Diego to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from San Diego with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Diego to Panama City

How far ahead should I book a flight from San Diego to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from San Diego to Panama City. Price data was last updated on September 12, 2025.

The best time to book flights from San Diego to Panama City is 88 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from San Diego to Panama City?

Currently, October is the cheapest month in which you can book a flight from San Diego to Panama City (average of $478). Flying from San Diego to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAN to PTY?

Find hourly flight availability from San Diego to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 29% on flights from San Diego to Panama City by exploring options for tickets in the afternoon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 17, 2025.
Peruse reviews from past customers who have flown with Delta, Copa Airlines, and United Airlines from San Diego to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Delta
8.0
Very good
7,961 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
Copa Airlines
7.6
Good
1,533 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
United Airlines
7.4
Good
8,926 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,961 reviews

Comfort

7.9

Entertainment

7.9

Food

7.3

Overall

8.0

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Aaron,Oct 2024

LAX - LHR

This was a flight operated by Virgin Atlantic in their Upper Class cabin. Overall, an outstanding experience.

Related info for your journey

Find useful and relevant information for your journey from San Diego to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How popular is this San Diego to Panama City flight route?

    The San Diego to Panama City Tocumen Intl flight path was viewed by 3 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

  • How long is the flight from San Diego to Panama City?

    There are many flights that can get you from San Diego to Panama City in 6h 10m. Fly via Copa Airlines, United Airlines, or Delta to get the fastest option. Airlines will cover a distance of 2910 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from San Diego to Panama City round-trip?

    According to our current data, Copa Airlines ($235), Delta ($355), and United Airlines ($403) offers the cheapest pricing from San Diego to Panama City. Copa Airlines is currently priced 58% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from San Diego to Panama City one-way?

    The cheapest airline one-way is United Airlines, with whom users have recently found tickets for as low as $194. However, be on the lookout for offers from American Airlines and Copa Airlines, as they are both options that can get you from San Diego to Panama City for a low price.

  • What are the cheapest flights from San Diego to Panama City?

    While on average a flight from San Diego to Panama City is generally $845, our data shows the cheapest flight currently is $170. When looking at the most popular route, (San Diego - Panama City Tocumen Intl), you can expect to pay $439 for that flight.

  • Can I find deals for flights from San Diego to Panama City that include hotel bookings?

    Yes. In addition to deals on San Diego to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Diego to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Diego to Panama City.

  • Can I find deals for business class flights from San Diego to Panama City?

    Yes. Cheapflights offers flight deals from San Diego to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Diego to Panama City?

    Currently, October is the cheapest month in which you can book a flight from San Diego to Panama City (average of $478). Flying from San Diego to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 4 airlines flying from San Diego to Panama City

Discover the top 4 airlines that operate flights from San Diego to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Copa AirlinesCheapest$235Average$495FlexibilityNo cancel feeOn-time70%
DeltaCheapest$355Average$564FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$403Average$617FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$586Average$701FlexibilityNo cancel feeOn-time71%

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