HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Panama City

$213+ Cheap flights from Minneapolis (MSP) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/27. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Aug 3 — Aug 101
Sun 8/3
Sun 8/10
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Minneapolis to Panama City with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from Minneapolis St Paul to Panama City Tocumen Intl are usually found in September or January, booked 85 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Minneapolis to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Minneapolis (MSP) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 29, 2025.

Round-trip from

$588
(American Airlines)

One-way from

$213
(Kiwi.com)

Popular in

December

Cheapest in

September

Average price

$955
From Minneapolis St Paul to Panama City Tocumen Intl
Search Deals
One-way flight from Minneapolis St Paul to Panama City Tocumen Intl
Search Deals
High demand for flights, 1% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2025
Search Deals

Find flight deals from Minneapolis to Panama City

Cheapest flights from Minneapolis to Panama City
Explore the most affordable flight options available from Minneapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 29, 2025.

This American Airlines deal was found by Cheapflights users on 7/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1912:51 pmMSP - PTY
2 stops23h 45mAmerican Airlines
Fri 5/151:55 pmPTY - MSP
1 stop8h 37mAmerican Airlines
Deal found 7/27$588
This United Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amMSP - PTY
2 stops12h 38mUnited Airlines
Sun 11/168:55 amPTY - MSP
1 stop15h 04mUnited Airlines
Deal found 7/28$608
This Mytrip deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/267:18 amMSP - PTY
3 stops37h 52mMultiple Airlines
Tue 9/210:05 pmPTY - MSP
3 stops23h 23mMultiple Airlines
Deal found 7/29$613
This Delta deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/195:35 amMSP - PTY
1 stop7h 20mDelta
Mon 9/292:10 pmPTY - MSP
1 stop10h 28mDelta
Deal found 7/29$673

Cheapflights Fare Finder

 
Customize your flight search to find flights from Minneapolis to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

Fly from

Minneapolis

Fly to

Panama City

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 11/19

12:51 pm-1:36 pm

2 stops23h 45m

Panama City Tocumen Intl

Fri 5/15

1:55 pm-10:32 pm

1 stop8h 37m

$588

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 1/25

5:15 pm-2:45 pm

2 stops20h 30m

Panama City Tocumen Intl

Sun 2/1

11:35 am-11:05 pm

1 stop12h 30m

$613

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 9/12

7:00 am-9:10 pm

2 stops14h 10m

Panama City Tocumen Intl

Fri 9/19

10:05 pm-8:26 am

3 stops34h 21m

$624

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 9/19

5:35 am-12:55 pm

1 stop7h 20m

Panama City Tocumen Intl

Mon 9/29

2:10 pm-12:38 am

1 stop10h 28m

$673

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 9/27

5:15 am-9:10 pm

3 stops15h 55m

$213

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 10/14

8:15 pm-12:56 pm

1 stop16h 41m

$369

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 10/15

8:00 am-6:37 pm

2 stops10h 37m

$416

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/28

Best time to book a flight from Minneapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Minneapolis with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama City

How far ahead should I book a flight from Minneapolis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Minneapolis to Panama City. Price data was last updated on July 25, 2025.

The price you pay for your flight from Minneapolis to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Minneapolis to Panama City?

Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama City (average of $478). Flying from Minneapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to PTY?

Find hourly flight availability from Minneapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 29, 2025.

When flying from Minneapolis to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 9% versus a flight in the morning.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 29, 2025.
See what other customers who have flown with Delta, United Airlines, and American Airlines from Minneapolis to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,977 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,899 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,977 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.2

Food

7.3

Crew

8.5

Overall

8.0

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Minneapolis to Panama City round-trip?

    Cheapflights users have booked flights from Minneapolis to Panama City round-trip from $588. Other airlines that can offer you cheap pricing are United Airlines, from $613, and Delta, from $673. American Airlines is 30% cheaper than the average price of flights available within the next 90 days to this destination.

  • Can I find deals for flights from Minneapolis to Panama City that include hotel bookings?

    Yes. In addition to deals on Minneapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Minneapolis to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama City.

  • Can I find deals for business class flights from Minneapolis to Panama City?

    Yes. Cheapflights offers flight deals from Minneapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Minneapolis to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama City (average of $478). Flying from Minneapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Minneapolis to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
Fargo to Panama City flights
Rochester to Panama City flights
Minneapolis to David flights
La Crosse to Panama City flights

Top 3 airlines flying from Minneapolis to Panama City

Discover the top 3 airlines that operate flights from Minneapolis to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$562Average$780FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$648Average$796FlexibilityNo cancel feeOn-time69%
DeltaCheapest$698Average$924FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.