What are the cheapest airlines flying from Minneapolis to Panama City round-trip?

Cheapflights users have booked flights from Minneapolis to Panama City round-trip from $583. Another airline that can offer you cheap pricing is Delta. United Airlines is 31% cheaper than the average price of flights available within the next 90 days to this destination.

What is the cheapest day to fly from Minneapolis to Panama City?

Travelers seeking maximum savings on their Minneapolis to Panama City flight should consider departing on Tuesday mornings when fares are most often at their lowest. Friday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

In terms of precipitation, rainfall in Panama City ranges from 0.4 - 13.4 inches per month. October is typically the wettest month, when rainfall can reach 13.4 in. February is typically the driest time to visit Panama City when rainfall is around 0.4 in.

If weather is an important factor for your trip to Panama City, use this chart to help with planning. For those seeking warmer temperatures, February is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 78.8 F).

What are the most popular airlines that fly from Minneapolis to Panama City?

Before booking your flight from Minneapolis to Panama City check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What is the cheapest day to fly round-trip from Minneapolis to Panama City?

Monday is generally a great day to depart. Flying on this day could help you save up to 13%.

How far in advance should I book a flight from Minneapolis to Panama City?

Find a great deal and save up to 112% by booking at least 54 days prior to your desired departure date, rather than waiting until the week of travel. According to our data, there are a number of flights available from Minneapolis to Panama City within the next two weeks, with the cheapest ticket starting at $1,093.

What is the cheapest month to fly from Minneapolis to Panama City?

The best pricing can be found in the month of September. Prices to Panama City from Minneapolis average $847. You can even find prices in September for less than $847, as users have found deals to Panama City from as low as $419. The month of December appears to be one of the more expensive times to travel to Panama City from Minneapolis. Flying in the targeted month can save you up to 14%.

Can I find deals for flights from Minneapolis to Panama City that include hotel bookings?

Yes. In addition to deals on Minneapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Minneapolis to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama City.

Can I find deals for business class flights from Minneapolis to Panama City?

Yes. Cheapflights offers flight deals from Minneapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$245+ Flights from Minneapolis to Panama City

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1. Tell us where you want to go

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Cheapflights Tip: The best prices from Minneapolis St Paul to Panama City Tocumen Intl are usually found in September or January, booked 85 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Minneapolis to Panama City

Round-trip from	$583 (United Airlines)
One-way from	$245 (Kiwi.com)
Popular in	December
Cheapest in	September
Average price	$844

From Minneapolis St Paul to Panama City Tocumen Intl

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One-way flight from Minneapolis St Paul to Panama City Tocumen Intl

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High demand for flights, 1% potential price rise

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Cheapest flight prices on average. 1% potential price decrease ($11 potential savings vs. average RT price).

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Average for round-trip flights in August 2025

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Find flight deals from Minneapolis to Panama City

Cheapest flights from Minneapolis to Panama City
Explore the most affordable flight options available from Minneapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

Tue 12/27:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Wed 12/248:55 amPTY - MSP

1 stop15h 20mUnited Airlines

Deal found 8/7

$583

Tue 12/27:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Mon 12/2211:55 pmPTY - MSP

2 stops16h 53mUnited Airlines

Deal found 8/7

$588

Sun 11/308:15 pmMSP - PTY

1 stop16h 37mDelta

Mon 12/223:20 pmPTY - MSP

1 stop10h 11mDelta

Deal found 8/7

$603

Thu 12/48:15 pmMSP - PTY

1 stop16h 37mDelta

Mon 12/223:20 pmPTY - MSP

1 stop18h 31mDelta

Deal found 8/4

$608

Sun 12/76:00 amMSP - PTY

2 stops13h 02mUnited Airlines

Mon 12/2211:55 pmPTY - MSP

2 stops16h 53mUnited Airlines

Deal found 8/4

$613

Wed 9/36:00 amMSP - PTY

3 stops18h 45mMultiple Airlines

Tue 9/93:20 amPTY - MSP

3 stops29h 06mMultiple Airlines

Deal found 8/6

$619

Sat 12/62:06 pmMSP - PTY

1 stop26h 01mUnited Airlines

Thu 12/184:41 pmPTY - MSP

2 stops23h 50mUnited Airlines

Deal found 8/4

$625

Fri 11/285:15 amMSP - PTY

1 stop13h 46mDelta

Mon 12/223:20 pmPTY - MSP

1 stop18h 31mDelta

Deal found 8/7

$628

Thu 12/48:15 pmMSP - PTY

1 stop16h 37mDelta

Sun 12/213:20 pmPTY - MSP

1 stop18h 31mDelta

Deal found 8/4

$633

Sat 12/67:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Fri 12/1910:00 amPTY - MSP

2 stops12h 59mUnited Airlines

Deal found 8/4

$638

Thu 11/278:00 amMSP - PTY

1 stop10h 38mUnited Airlines

Thu 12/411:35 amPTY - MSP

1 stop12h 16mUnited Airlines

Deal found 8/6

$648

Best flights from Minneapolis to Panama City
Discover carefully curated flight deals from Minneapolis to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2025.

Tue 12/27:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Wed 12/248:55 amPTY - MSP

1 stop15h 20mUnited Airlines

Deal found 8/7

$583

Sun 11/308:15 pmMSP - PTY

1 stop16h 37mDelta

Mon 12/223:20 pmPTY - MSP

1 stop10h 11mDelta

Deal found 8/7

$603

Mon 1/512:41 pmMSP - PTY

2 stops23h 29mAmerican Airlines

Sat 1/244:40 pmPTY - MSP

2 stops17h 18mAmerican Airlines

Deal found 8/6

$608

Wed 9/36:00 amMSP - PTY

3 stops18h 45mMultiple Airlines

Tue 9/93:20 amPTY - MSP

3 stops29h 06mMultiple Airlines

Deal found 8/6

$619

Tue 12/27:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Mon 12/2211:55 pmPTY - MSP

2 stops16h 53mUnited Airlines

Deal found 8/7

$588

Fri 11/285:15 amMSP - PTY

1 stop13h 46mDelta

Mon 12/223:20 pmPTY - MSP

1 stop18h 31mDelta

Deal found 8/7

$628

Sun 12/77:45 amMSP - PTY

1 stop8h 22mUnited Airlines

Thu 12/188:55 amPTY - MSP

2 stops14h 04mUnited Airlines

Deal found 8/4

$613

Thu 12/48:15 pmMSP - PTY

1 stop16h 37mDelta

Sun 12/213:20 pmPTY - MSP

1 stop18h 31mDelta

Deal found 8/4

$633

Sun 1/252:00 pmMSP - PTY

1 stop28h 38mUnited Airlines

Sun 2/111:35 amPTY - MSP

1 stop12h 30mUnited Airlines

Deal found 8/7

$620

Sat 12/62:06 pmMSP - PTY

1 stop26h 01mUnited Airlines

Thu 12/184:41 pmPTY - MSP

2 stops23h 50mUnited Airlines

Deal found 8/4

$625

Sat 12/67:45 amMSP - PTY

1 stop10h 53mUnited Airlines

Fri 12/1910:00 amPTY - MSP

2 stops12h 59mUnited Airlines

Deal found 8/4

$638

Last-minute flights from Minneapolis to Panama City
Discover last-minute flight deals from Minneapolis to Panama City. Data last updated August 7, 2025 and is based on user searches.

Tue 8/125:47 pmMSP - PTY

3 stops39h 08mMultiple Airlines

Wed 8/203:20 amPTY - MSP

3 stops28h 57mMultiple Airlines

Deal found 8/6

$733

Fri 8/156:24 amMSP - PTY

3 stops32h 16mMultiple Airlines

Sat 8/163:20 amPTY - MSP

3 stops28h 57mMultiple Airlines

Deal found 8/7

$811

Sun 8/179:22 amMSP - PTY

3 stops29h 18mMultiple Airlines

Sat 8/239:55 amPTY - MSP

3 stops26h 11mMultiple Airlines

Deal found 8/6

$734

Wed 9/36:00 amMSP - PTY

3 stops18h 45mMultiple Airlines

Tue 9/93:20 amPTY - MSP

3 stops29h 06mMultiple Airlines

Deal found 8/6

$619

Thu 9/44:00 pmMSP - PTY

3 stops32h 45mMultiple Airlines

Thu 9/119:55 amPTY - MSP

3 stops35h 57mMultiple Airlines

Deal found 8/7

$720

Fri 9/199:00 amMSP - PTY

3 stops23h 55mMultiple Airlines

Thu 9/253:20 amPTY - MSP

2 stops35h 43mMultiple Airlines

Deal found 8/5

$691

Fri 9/195:45 pmMSP - PTY

2 stops20h 46mAmerican Airlines

Fri 9/263:31 pmPTY - MSP

2 stops22h 43mAmerican Airlines

Deal found 8/5

$721

Tue 9/2312:47 pmMSP - PTY

2 stops24h 08mAmerican Airlines

Tue 9/301:45 pmPTY - MSP

2 stops20h 23mAmerican Airlines

Deal found 8/4

$653

Tue 9/238:00 amMSP - PTY

1 stop10h 37mUnited Airlines

Tue 9/303:30 pmPTY - MSP

1 stop25h 38mUnited Airlines

Deal found 8/4

$661

One-way flights from Minneapolis to Panama City
Search for one-way flight options from Minneapolis to Panama City. Find affordable one-way fares based on user searches. Data last updated August 7, 2025.

Thu 10/29:31 amMSP - PTY

3 stops35h 39mMultiple Airlines

Deal found 8/7

$245

Fri 10/105:06 pmMSP - PTY

1 stop12h 27mCopa Airlines

Deal found 8/7

$1,050

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 12/2

7:45 am-7:38 pm

1 stop10h 53m

Panama City Tocumen Intl

Wed 12/24

8:55 am-11:15 pm

1 stop15h 20m

$583

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Tue 12/2

7:45 am-7:38 pm

1 stop10h 53m

Panama City Tocumen Intl

Mon 12/22

11:55 pm-3:48 pm

2 stops16h 53m

$588

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 11/30

8:15 pm-1:52 pm

1 stop16h 37m

Panama City Tocumen Intl

Mon 12/22

3:20 pm-12:31 am

1 stop10h 11m

$603

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Mon 1/5

12:41 pm-1:10 pm

2 stops23h 29m

Panama City Tocumen Intl

Sat 1/24

4:40 pm-8:58 am

2 stops17h 18m

$608

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 12/7

7:45 am-5:07 pm

1 stop8h 22m

Panama City Tocumen Intl

Thu 12/18

8:55 am-9:59 pm

2 stops14h 04m

$613

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Wed 9/3

6:00 am-12:45 am

3 stops18h 45m

Panama City Tocumen Intl

Tue 9/9

3:20 am-8:26 am

3 stops29h 06m

$619

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sun 1/25

2:00 pm-7:38 pm

1 stop28h 38m

Panama City Tocumen Intl

Sun 2/1

11:35 am-11:05 pm

1 stop12h 30m

$620

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Sat 12/6

2:06 pm-5:07 pm

1 stop26h 01m

Panama City Tocumen Intl

Thu 12/18

4:41 pm-3:31 pm

2 stops23h 50m

$625

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Fri 11/28

5:15 am-8:01 pm

1 stop13h 46m

Panama City Tocumen Intl

Mon 12/22

3:20 pm-8:51 am

1 stop18h 31m

$628

MinneapolisPanama City

MSP - PTY

MSPPTY

Minneapolis St Paul

Thu 12/4

8:15 pm-1:52 pm

1 stop16h 37m

Panama City Tocumen Intl

Sun 12/21

3:20 pm-8:51 am

1 stop18h 31m

$633

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/7

Showing 1-10 of 13 results

Best time to book a flight from Minneapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Minneapolis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama City

How far ahead should I book a flight from Minneapolis to Panama City?

The price you pay for your flight from Minneapolis to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 85 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from Minneapolis to Panama City?

Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama City (average of $478). Flying from Minneapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MSP to PTY?

When flying from Minneapolis to Panama City, the time of day you fly usually plays a role in the price. Save by searching for a flight at noon, which can drop the price by up to 9% versus a flight in the morning.

Reviews of airlines servicing Panama City

See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Minneapolis to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

8.0

Very good

7,987 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Delta

8.0

Very good

7,987 reviews

Delta

8.0

Very good

7,987 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Copa Airlines

7.5

Good

1,500 reviews

Delta

8.0

Very good

7,987 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

United Airlines

7.4

Good

8,916 reviews

Delta

8.0

Very good

7,987 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

American Airlines

7.2

Good

10,000 reviews

Delta

8.0

Very good

7,987 reviews

Reviews

1 / 20

10.0

Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

What are the cheapest airlines flying from Minneapolis to Panama City round-trip?
Cheapflights users have booked flights from Minneapolis to Panama City round-trip from $583. Another airline that can offer you cheap pricing is Delta. United Airlines is 31% cheaper than the average price of flights available within the next 90 days to this destination.
Can I find deals for flights from Minneapolis to Panama City that include hotel bookings?
Yes. In addition to deals on Minneapolis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Minneapolis to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Minneapolis to Panama City.
Can I find deals for business class flights from Minneapolis to Panama City?
Yes. Cheapflights offers flight deals from Minneapolis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Minneapolis to Panama City?
Currently, October is the cheapest month in which you can book a flight from Minneapolis to Panama City (average of $478). Flying from Minneapolis to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 3 airlines flying from Minneapolis to Panama City

Airline	Cheapest	Average	Flexibility	On-time
American Airlines	Cheapest$562	Average$779	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$648	Average$803	FlexibilityNo cancel fee	On-time69%
Delta	Cheapest$694	Average$922	FlexibilityNo cancel fee	On-timeN/A

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$245+ Cheap flights from Minneapolis (MSP) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/2. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Minneapolis to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Minneapolis St Paul to Panama City Tocumen Intl are usually found in September or January, booked 85 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from Minneapolis to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Find flight deals from Minneapolis to Panama City

Cheapest flights from Minneapolis to Panama CityExplore the most affordable flight options available from Minneapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

Explore the most affordable flight options available from Minneapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Minneapolis to Panama City that are best for you.

Best time to book a flight from Minneapolis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Minneapolis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Minneapolis to Panama City

How far ahead should I book a flight from Minneapolis to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Minneapolis to Panama City. Price data was last updated on August 1, 2025.

What is the cheapest month to book a flight from Minneapolis to Panama City?

What is the cheapest time of day to fly from MSP to PTY?

Find hourly flight availability from Minneapolis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2025.

Reviews of airlines servicing Panama City

See what other customers who have flown with Delta, Copa Airlines, and United Airlines from Minneapolis to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Minneapolis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What are the cheapest airlines flying from Minneapolis to Panama City round-trip?

Can I find deals for flights from Minneapolis to Panama City that include hotel bookings?

How can I find direct flights from Minneapolis to Panama City?

Can I find deals for business class flights from Minneapolis to Panama City?

What is the cheapest month to book a flight from Minneapolis to Panama City?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Minneapolis to Panama City

See prices for flight routes from nearby airports that may be better suited for you.

Top 3 airlines flying from Minneapolis to Panama City

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Cheapest flights from Minneapolis to Panama City
Explore the most affordable flight options available from Minneapolis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2025.