$335+ Cheap flights from Minneapolis (MSP) to Panama
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/10. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Jul 23 — Jul 301
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Minneapolis to PanamaExplore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 23, 2026.
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/216:15 am
MSP
- PTY
1 stop13h 16m
United Airlines
Tue 9/299:45 am
PTY
- MSP
1 stop13h 57m
United Airlines
Deal found 6/23![United Airlines logo]()
$705
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:00 am
MSP
- PTY
2 stops10h 37m
United Airlines
Wed 9/303:30 pm
PTY
- MSP
2 stops18h 50m
United Airlines
Deal found 6/23![United Airlines logo]()
$709
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/3010:22 am
MSP
- PTY
1 stop9h 09m
United Airlines
Wed 11/1810:00 am
PTY
- MSP
1 stop15h 09m
United Airlines
Deal found 6/22![United Airlines logo]()
$715
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:35 am
MSP
- PTY
1 stop11h 02m
United Airlines
Fri 10/210:00 am
PTY
- MSP
1 stop12h 54m
United Airlines
Deal found 6/23![United Airlines logo]()
$730
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:55 pm
MSP
- PTY
2 stops19h 19m
United Airlines
Thu 10/13:30 pm
PTY
- MSP
2 stops18h 50m
United Airlines
Deal found 6/23![United Airlines logo]()
$734
This American Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:47 pm
MSP
- PTY
2 stops18h 29m
American Airlines
Tue 10/133:35 pm
PTY
- MSP
2 stops25h 48m
American Airlines
Deal found 6/23![American Airlines logo]()
$742
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/2510:22 am
MSP
- PTY
1 stop9h 09m
United Airlines
Fri 10/29:45 am
PTY
- MSP
1 stop13h 57m
United Airlines
Deal found 6/23![United Airlines logo]()
$755
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
MSP
- PTY
2 stops13h 02m
United Airlines
Sun 11/88:55 am
PTY
- MSP
1 stop14h 54m
United Airlines
Deal found 6/22![United Airlines logo]()
$759
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/311:52 pm
MSP
- PTY
2 stops23h 44m
American Airlines
Sun 11/82:43 pm
PTY
- MSP
1 stop9h 10m
American Airlines
Deal found 6/21![American Airlines logo]()
$764
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am
MSP
- DAV
2 stops25h 50m
United Airlines
Thu 11/59:48 am
DAV
- MSP
2 stops26h 12m
United Airlines
Deal found 6/20![United Airlines logo]()
$1,275
Best flights from Minneapolis to PanamaDiscover carefully curated flight deals from Minneapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
Discover carefully curated flight deals from Minneapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 23, 2026.
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/307:40 am
MSP
- PTY
1 stop10h 57m
United Airlines
Wed 11/188:55 am
PTY
- MSP
3 stops24h 51m
United Airlines
Deal found 6/19![United Airlines logo]()
$715
This Delta deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:30 pm
MSP
- PTY
1 stop18h 25m
Delta
Wed 8/192:20 pm
PTY
- MSP
1 stop10h 02m
Delta
Deal found 6/21![Delta logo]()
$770
This United Airlines deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am
MSP
- PTY
2 stops13h 02m
United Airlines
Sun 11/88:55 am
PTY
- MSP
2 stops11h 39m
United Airlines
Deal found 6/18![United Airlines logo]()
$769
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:35 am
MSP
- PTY
1 stop11h 02m
United Airlines
Tue 10/1310:00 am
PTY
- MSP
1 stop12h 54m
United Airlines
Deal found 6/23![United Airlines logo]()
$770
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:35 am
MSP
- PTY
1 stop8h 37m
United Airlines
Wed 8/193:30 pm
PTY
- MSP
2 stops17h 09m
United Airlines
Deal found 6/21![United Airlines logo]()
$784
This United Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/16:00 am
MSP
- DAV
2 stops25h 50m
United Airlines
Thu 11/59:48 am
DAV
- MSP
2 stops26h 12m
United Airlines
Deal found 6/20![United Airlines logo]()
$1,275
Last-minute flights from Minneapolis to PanamaDiscover last-minute flight deals from Minneapolis to Panama. Data last updated June 23, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Panama. Data last updated June 23, 2026 and is based on user searches.
This Mytrip deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:05 pm
MSP
- PTY
2 stops36h 50m
Multiple Airlines
Fri 7/33:10 pm
PTY
- MSP
2 stops22h 48m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$770
This Orbitz deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/111:10 pm
MSP
- PTY
2 stops36h 45m
Avianca
Fri 7/175:30 am
PTY
- MSP
2 stops15h 53m
Avianca
Deal found 6/19![Avianca logo]()
$780
This Avianca deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/111:10 pm
MSP
- PTY
2 stops36h 45m
Avianca
Thu 7/163:50 pm
PTY
- MSP
2 stops29h 33m
Avianca
Deal found 6/19![Avianca logo]()
$797
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/121:10 pm
MSP
- PTY
2 stops36h 45m
Avianca
Fri 7/175:30 am
PTY
- MSP
2 stops15h 53m
Avianca
Deal found 6/20![Avianca logo]()
$806
This Avianca deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/121:10 pm
MSP
- PTY
2 stops36h 45m
Avianca
Thu 7/163:50 pm
PTY
- MSP
2 stops29h 33m
Avianca
Deal found 6/20![Avianca logo]()
$823
This Mytrip deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:10 pm
MSP
- PTY
2 stops36h 45m
Multiple Airlines
Tue 7/285:30 am
PTY
- MSP
2 stops32h 18m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$836
This Mytrip deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/231:45 pm
MSP
- PTY
2 stops27h 15m
Multiple Airlines
Thu 7/303:10 pm
PTY
- MSP
2 stops30h 29m
Multiple Airlines
Deal found 6/18![Multiple Airlines logo]()
$828
This Mytrip deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/261:10 pm
MSP
- PTY
2 stops36h 45m
Multiple Airlines
Sat 8/14:25 am
PTY
- MSP
2 stops30h 32m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$812
One-way flights from Minneapolis to PanamaSearch for one-way flight options from Minneapolis to Panama. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
Search for one-way flight options from Minneapolis to Panama. Find affordable one-way fares based on user searches. Data last updated June 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/102:24 pm
MSP
- PTY
2 stops17h 42m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$335
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:24 pm
MSP
- PTY
2 stops17h 42m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$349
This Mytrip deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/41:10 pm
MSP
- PTY
2 stops36h 45m
Avianca
Deal found 6/20![Avianca logo]()
$383
This Mytrip deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:00 am
MSP
- PTY
2 stops27h 15m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$397
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1010:15 pm
MSP
- PTY
3 stops26h 20m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$399
This Mytrip deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:20 am
MSP
- PTY
3 stops18h 35m
Multiple Airlines
Deal found 6/20![Multiple Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1312:51 pm
MSP
- PTY
2 stops23h 45m
American Airlines
Deal found 6/19![American Airlines logo]()
$410
This United Airlines deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am
MSP
- PTY
1 stop13h 02m
United Airlines
Deal found 6/19![United Airlines logo]()
$415
This Kiwi.com deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:55 am
MSP
- PTY
2 stops15h 40m
Multiple Airlines
Deal found 6/19![Multiple Airlines logo]()
$422
Find flight deals from Minneapolis to Panama
Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated June 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $705 (United Airlines) |
One-way from | $335 (Kiwi.com) |
Popular in | August |
Cheapest in | November |
Average price | $864 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Wed 9/30
7:40 am-6:37 pm
1 stop10h 57m
Panama City Tocumen Intl
Wed 11/18
8:55 am-8:46 am
3 stops24h 51m
$715
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Sat 10/31
6:00 am-7:02 pm
2 stops13h 02m
Panama City Tocumen Intl
Sun 11/8
8:55 am-7:34 pm
2 stops11h 39m
$769
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Mon 8/10
6:30 pm-12:55 pm
1 stop18h 25m
Panama City Tocumen Intl
Wed 8/19
2:20 pm-12:22 am
1 stop10h 02m
$770
Quickest round-trip
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Thu 9/10
7:35 am-6:37 pm
1 stop11h 02m
Panama City Tocumen Intl
Tue 10/13
10:00 am-10:54 pm
1 stop12h 54m
$770
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Mon 8/10
7:35 am-4:12 pm
1 stop8h 37m
Panama City Tocumen Intl
Wed 8/19
3:30 pm-8:39 am
2 stops17h 09m
$784
MinneapolisDavid
MSP - DAV
MSPDAV
Minneapolis St Paul
Sun 11/1
6:00 am-8:50 am
2 stops25h 50m
David Enrique Malek
Thu 11/5
9:48 am-11:00 am
2 stops26h 12m
$1,275
Cheapest one-way
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Mon 8/10
2:24 pm-8:06 am
2 stops17h 42m
$335
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Wed 8/12
2:24 pm-8:06 am
2 stops17h 42m
$349
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Sat 8/1
10:15 pm-12:35 am
3 stops26h 20m
$401
MinneapolisPanama City
MSP - PTY
MSPPTY
Minneapolis St Paul
Tue 8/4
7:20 am-1:55 am
3 stops18h 35m
$405
Showing 1-10 of 14 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
MSP-PTY
MSP-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Panama
MSP-PA0
MSP-PTY
MSP-DAV
What is the cheapest month to book a flight from Minneapolis to Panama?
Currently, January is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $522). Flying from Minneapolis to Panama in May is currently the most expensive (average of $844). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated June 23, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Comfort
7.8
Food
7.2
Entertainment
7.8
Boarding
8.1
Crew
8.5
Overall
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Minneapolis to Panama
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Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to Panama by cabin class
Find flights from Minneapolis to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and Panama flights
Browse other Minneapolis and Panama flight options. Last updated on June 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Minneapolis to Panama
Discover the top 4 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$603 | Average$798 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$633 | Average$934 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$633 | Average$759 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$646 | Average$774 | FlexibilityNo cancel fee | On-time70% |