$262+ Cheap flights from Minneapolis (MSP) to Panama
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/4. Fares are subject to change and may not be available on all flights or dates of travel.
MSP — PTY
Dec 9 — Dec 161
Round-trip
1 adult, Economy
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Find cheap flights from Minneapolis to Panama with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Minneapolis to Panama
Cheapest
Best
Last-minute
One-way
Cheapest flights from Minneapolis to PanamaExplore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
Explore the most affordable flight options available from Minneapolis to Panama. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop11h 08m
Wed 4/1410:55 pm -
1 stop18h 07m
Deal found 11/9![United Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:30 am -
1 stop11h 08m
Tue 12/18:55 am -
1 stop15h 03m
Deal found 11/5![United Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:30 am -
1 stop11h 08m
Wed 11/188:55 am -
1 stop15h 03m
Deal found 11/5![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
1 stop24h 42m
Sat 12/198:55 am -
1 stop15h 02m
Deal found 11/4![United Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:20 am -
1 stop11h 18m
Sun 12/1311:35 am -
1 stop12h 24m
Deal found 11/8![United Airlines logo]()
$741
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
2 stops12h 38m
Tue 12/18:55 am -
2 stops15h 35m
Deal found 11/4![United Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:30 am -
1 stop11h 08m
Sat 11/218:55 am -
1 stop15h 04m
Deal found 11/8![United Airlines logo]()
$771
Best flights from Minneapolis to PanamaDiscover carefully curated flight deals from Minneapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
Discover carefully curated flight deals from Minneapolis to Panama that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/249:38 am -
1 stop9h 24m
Thu 3/410:00 am -
1 stop13h 11m
Deal found 11/8![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/99:50 am -
1 stop9h 12m
Wed 5/1910:00 am -
1 stop13h 05m
Deal found 11/7![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/89:45 am -
1 stop9h 17m
Wed 2/178:55 am -
1 stop9h 17m
Deal found 11/6![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/295:44 pm -
1 stop10h 20m
Mon 4/57:55 am -
1 stop15h 10m
Deal found 11/6![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/228:00 am -
2 stops11h 02m
Wed 3/38:55 am -
1 stop9h 17m
Deal found 11/5![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/157:30 am -
1 stop8h 42m
Mon 2/228:55 am -
1 stop9h 17m
Deal found 11/8![United Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/213:14 pm -
2 stops22h 31m
Mon 3/14:41 pm -
2 stops18h 47m
Deal found 11/9![United Airlines logo]()
$594
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/158:00 am -
1 stop10h 38m
Mon 3/223:41 pm -
1 stop25h 30m
Deal found 11/4![United Airlines logo]()
$601
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/107:30 am -
1 stop11h 08m
Sat 2/204:41 pm -
1 stop19h 16m
Deal found 11/5![United Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/286:45 pm -
2 stops24h 17m
Sat 3/611:55 pm -
2 stops15h 22m
Deal found 11/8![United Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/266:00 am -
2 stops13h 02m
Sun 1/314:41 pm -
2 stops24h 09m
Deal found 11/6![United Airlines logo]()
$624
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/316:00 pm -
2 stops37h 49m
Thu 2/49:47 am -
2 stops26h 09m
Deal found 11/4![United Airlines logo]()
$1,049
Last-minute flights from Minneapolis to PanamaDiscover last-minute flight deals from Minneapolis to Panama. Data last updated November 9, 2026 and is based on user searches.
Discover last-minute flight deals from Minneapolis to Panama. Data last updated November 9, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:30 am -
1 stop11h 08m
Tue 12/18:55 am -
1 stop15h 03m
Deal found 11/5![United Airlines logo]()
$681
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:30 am -
1 stop11h 08m
Wed 11/188:55 am -
1 stop15h 03m
Deal found 11/5![United Airlines logo]()
$711
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:30 am -
1 stop11h 08m
Sat 11/218:55 am -
1 stop15h 04m
Deal found 11/8![United Airlines logo]()
$771
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:30 am -
1 stop11h 08m
Wed 4/1410:55 pm -
1 stop18h 07m
Deal found 11/9![United Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
2 stops12h 38m
Tue 12/18:55 am -
2 stops15h 35m
Deal found 11/4![United Airlines logo]()
$758
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/66:20 pm -
1 stop24h 42m
Sat 12/198:55 am -
1 stop15h 02m
Deal found 11/4![United Airlines logo]()
$723
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:20 am -
1 stop11h 18m
Sun 12/1311:35 am -
1 stop12h 24m
Deal found 11/8![United Airlines logo]()
$741
One-way flights from Minneapolis to PanamaSearch for one-way flight options from Minneapolis to Panama. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
Search for one-way flight options from Minneapolis to Panama. Find affordable one-way fares based on user searches. Data last updated November 9, 2026.
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/45:09 pm -
1 stop11h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$262
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:44 pm -
2 stops23h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$267
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/197:30 am -
1 stop11h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![United Airlines logo]()
$292
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:45 pm -
2 stops23h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$297
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/31:41 pm -
2 stops24h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$362
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/35:13 am -
1 stop8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![United Airlines logo]()
$365
This BusinessClass deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure BusinessClass is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:00 am -
1 stop12h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Copa Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/72:52 pm -
3 stops45h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$445
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/163:23 pm -
2 stops22h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![United Airlines logo]()
$447
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:34 pm -
2 stops19h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![American Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/168:31 pm -
3 stops22h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![Multiple Airlines logo]()
$458
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/296:05 am -
3 stops29h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$612
Find flight deals from Minneapolis to Panama
Keep the following information in mind while searching for Minneapolis to Panama flight deals. Data was last updated November 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $589 (United Airlines) |
One-way from | $262 (United Airlines) |
Popular in | December |
Cheapest in | November |
Average price | $704 |
Cheapflights Fare Finder
Customize your flight search to find flights from Minneapolis to Panama that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
Use the filters below to find and compare flights from Minneapolis to Panama that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 3/1
7:30 am-5:12 pm
1 stop8h 42m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 3/1
3:03 pm-3:24 pm
2 stops23h 21m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 1/4
11:29 am-5:10 am
2 stops16h 41m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 2/15
9:38 am-8:02 pm
1 stop9h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Thu 2/18
9:38 am-8:02 pm
1 stop9h 24m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Wed 2/17
7:30 am-5:12 pm
1 stop8h 42m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$262
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Fri 2/19
6:00 am-8:02 pm
2 stops13h 02m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$292
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Sat 2/20
7:30 am-7:38 pm
1 stop11h 08m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$292
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Thu 1/7
5:50 pm-7:38 pm
1 stop24h 48m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$310
MinneapolisPanama City
MSP Minneapolis St Paul - PTY Panama City Tocumen Intl
MSPPTY
Minneapolis St Paul
Mon 11/30
7:30 am-7:38 pm
1 stop11h 08m
Panama City Tocumen Intl
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$447
Showing 1-10 of 26 resultsSorted by cheapest first
Best time to book a flight from Minneapolis to Panama
Have a flexible travel schedule? Discover the best time to fly to Panama from Minneapolis with our price prediction graph.
MSP-PTY
MSP-BOC
MSP-DAV
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Minneapolis to Panama
MSP-PA0
MSP-PTY
MSP-BOC
MSP-DAV
What is the cheapest month to book a flight from Minneapolis to Panama?
Currently, November is the cheapest month in which you can book a flight from Minneapolis to Panama (average of $704). Flying from Minneapolis to Panama in December is currently the most expensive (average of $988). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from Minneapolis to Panama?
The price you pay for your flight from Minneapolis to Panama may vary depending on when you book. For the best chance of a lower fare, look to book 9 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Reviews of airlines servicing Panama
Get insights into the airlines that provide service to Panama. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama. Reviews last updated November 9, 2026.
See what other customers who have flown with Delta,Copa Airlines, andUnited Airlines from Minneapolis to Panama have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Entertainment
7.8
Boarding
8.1
Overall
7.8
Comfort
7.8
Crew
8.5
Food
7.2
Reviews
1 / 20
8.0
ExcellentRona,Feb 2024
MSP - DEN
Related info for your journey
Find useful and relevant information for your journey from Minneapolis to Panama. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Minneapolis to Panama
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Panama by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Minneapolis to Panama by cabin class
Find flights from Minneapolis to Panama, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Minneapolis and Panama flights
Browse other Minneapolis and Panama flight options. Last updated on November 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Minneapolis to Panama
Discover the top 4 airlines that operate flights from Minneapolis to Panama. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$569 | Average$781 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$577 | Average$768 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$636 | Average$789 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$704 | Average$934 | FlexibilityNo cancel fee | On-timeN/A |