Panama City

$232+ Cheap flights from Cleveland (CLE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Nov 9 — Nov 161
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Find flight deals from Cleveland to Panama City

Cheapest flights from Cleveland to Panama City
Explore the most affordable flight options available from Cleveland to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 10, 2025.

This Kiwi.com deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/115:45 amCLE - PTY
2 stops19h 15mMultiple Airlines
Wed 12/109:33 pmPTY - CLE
1 stop27h 15mMultiple Airlines
Deal found 10/7$499
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amCLE - PTY
1 stop7h 47mAmerican Airlines
Sat 12/62:50 pmPTY - CLE
1 stop9h 06mAmerican Airlines
Deal found 10/8$510
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/102:56 pmCLE - PTY
1 stop23h 49mUnited Airlines
Tue 12/911:35 amPTY - CLE
1 stop10h 15mUnited Airlines
Deal found 10/7$521
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/205:32 pmCLE - PTY
1 stop20h 11mAmerican Airlines
Fri 12/192:53 pmPTY - CLE
2 stops19h 05mAmerican Airlines
Deal found 10/7$526
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:15 amCLE - PTY
1 stop8h 59mUnited Airlines
Wed 4/1510:55 pmPTY - CLE
1 stop8h 43mUnited Airlines
Deal found 10/8$530
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/226:00 amCLE - PTY
2 stops9h 03mAmerican Airlines
Wed 4/151:55 pmPTY - CLE
2 stops19h 02mAmerican Airlines
Deal found 10/8$534
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/76:15 amCLE - PTY
1 stop13h 23mUnited Airlines
Sat 12/610:00 amPTY - CLE
1 stop10h 18mUnited Airlines
Deal found 10/7$550
This Kiwi.com deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/96:00 amCLE - PTY
2 stops32h 55mMultiple Airlines
Wed 11/129:33 pmPTY - CLE
1 stop22h 56mMultiple Airlines
Deal found 10/9$552
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/95:28 pmCLE - PTY
2 stops20h 21mAmerican Airlines
Wed 11/122:49 pmPTY - CLE
2 stops19h 41mAmerican Airlines
Deal found 10/9$554

Cheap flight deals from Cleveland to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 10, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$490
(Delta)

One-way from

$232
(Delta)

Popular in

December

Cheapest in

November

Average price

$570
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
From Cleveland Hopkins Intl to Panama City Tocumen Intl
One-way flight from Cleveland Hopkins Intl to Panama City Tocumen Intl
Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
Cheapest flight prices on average. 5% potential price decrease ($29 potential savings vs. average RT price).
Average for round-trip flights in October 2025

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
Use the filters below to find and compare flights from Cleveland to Panama City that are best for you.

Fly from

Cleveland

Fly to

Panama City

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/22

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Tue 2/24

2:30 pm-10:39 pm

1 stop8h 09m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 2/10

7:00 am-2:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Wed 2/11

3:27 pm-9:15 am

1 stop17h 48m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 2/4

12:14 pm-8:02 pm

1 stop7h 48m

Panama City Tocumen Intl

Wed 2/11

11:35 am-9:58 pm

1 stop10h 23m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/9

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Wed 2/11

3:27 pm-9:15 am

1 stop17h 48m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 2/10

7:00 am-2:02 pm

1 stop7h 02m

Panama City Tocumen Intl

Thu 2/12

3:27 pm-9:15 am

1 stop17h 48m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 3/2

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Thu 3/12

2:20 pm-12:37 am

1 stop9h 17m

$490

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 3/2

5:16 pm-1:10 pm

2 stops19h 54m

Panama City Tocumen Intl

Thu 3/12

1:50 pm-8:42 am

2 stops17h 52m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 2/6

6:00 am-1:27 pm

1 stop7h 27m

Panama City Tocumen Intl

Wed 2/11

2:27 pm-11:45 am

2 stops21h 18m

$494

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 2/8

12:00 pm-2:02 pm

1 stop26h 02m

Panama City Tocumen Intl

Wed 2/11

3:27 pm-9:15 am

1 stop17h 48m

$498

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 2/8

2:35 pm-2:02 pm

1 stop23h 27m

Panama City Tocumen Intl

Thu 2/12

3:27 pm-12:37 am

1 stop9h 10m

$498

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/8

Showing 1-10 of 18 results
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Compare providers for flights from Cleveland to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cleveland to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cleveland-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Cleveland-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Cleveland-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cleveland-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cleveland to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama City

What is the cheapest month to book a flight from Cleveland to Panama City?

Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $384). Flying from Cleveland to Panama City in May is currently the most expensive (average of $567). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to PTY?

Find hourly flight availability from Cleveland to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 10, 2025.

It’s optimal to fly from Cleveland to Panama City in the morning. By choosing this option you can save up to 22% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Cleveland to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 10, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Cleveland to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
8.0
Very good

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good
8.0
Very good

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
8.0
Very good

Crew

8.5

Food

7.3

Overall

8.0

Entertainment

7.9

Boarding

8.2

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Cleveland to Panama City?

    There are many flights that can get you from Cleveland to Panama City in 7h 02m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. Cleveland and Panama City are separated by a distance of 2238 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Cleveland to Panama City round-trip?

    Cheapflights users have booked flights from Cleveland to Panama City round-trip from $389. Other airlines that can offer you cheap pricing are American Airlines, from $469, and United Airlines, from $469. You may be able to fly from Cleveland to Panama City for 34% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Cleveland to Panama City one-way?

    One-way options have recently been found by users for as low as $232 on American Airlines. Other airlines that offer cheap prices include Delta from $232 and United Airlines from $232 one-way.

  • Can I find deals for flights from Cleveland to Panama City that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama City.

  • Can I find deals for business class flights from Cleveland to Panama City?

    Yes. Cheapflights offers flight deals from Cleveland to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $384). Flying from Cleveland to Panama City in May is currently the most expensive (average of $567). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 3 airlines flying from Cleveland to Panama City

Discover the top 3 airlines that operate flights from Cleveland to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 10, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$570FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$469Average$715FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$601FlexibilityNo cancel feeOn-time69%

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