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$211+ Cheap flights from Cleveland (CLE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Feb 14 — Feb 211
Sat 2/14
Sat 2/21
1 adult, Economy
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Cheap flight deals from Cleveland to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 15, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$511
(United Airlines)

One-way from

$243
(Delta)

Popular in

August

Cheapest in

November

Average price

$571
Provider with most accurate pricing for Cleveland Hopkins Intl-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Cleveland Hopkins Intl-Panama City Tocumen Intl flights.
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From Cleveland Hopkins Intl to Panama City Tocumen Intl
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One-way flight from Cleveland Hopkins Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 7% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($16 potential savings vs. average RT price).
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Average for round-trip flights in January 2026
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Find flight deals from Cleveland to Panama City

Cheapest flights from Cleveland to Panama City
Explore the most affordable flight options available from Cleveland to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 15, 2026.

This United Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1312:30 pm
CLE
-
PTY
1 stop8h 01m
United Airlines
Tue 5/267:55 am
PTY
-
CLE
1 stop12h 56m
United Airlines
Deal found 1/14$511
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/136:04 am
CLE
-
PTY
1 stop7h 32m
American Airlines
Tue 5/261:10 pm
PTY
-
CLE
2 stops20h 42m
American Airlines
Deal found 1/14$515
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/227:18 pm
CLE
-
PTY
2 stops13h 32m
Multiple Airlines
Thu 2/2612:03 pm
PTY
-
CLE
1 stop30h 06m
Multiple Airlines
Deal found 1/13$522
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/233:13 pm
CLE
-
PTY
2 stops17h 37m
Multiple Airlines
Wed 2/2512:03 pm
PTY
-
CLE
1 stop26h 00m
Multiple Airlines
Deal found 1/13$525
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/249:30 am
CLE
-
PTY
1 stop11h 04m
Multiple Airlines
Wed 2/255:50 pm
PTY
-
CLE
2 stops27h 47m
Multiple Airlines
Deal found 1/13$528
This United Airlines deal was found by Cheapflights users on 1/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
CLE
-
PTY
1 stop9h 14m
United Airlines
Fri 4/1010:00 am
PTY
-
CLE
1 stop10h 59m
United Airlines
Deal found 1/15$531
This Avianca deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/287:55 pm
CLE
-
PTY
2 stops14h 35m
Multiple Airlines
Wed 3/117:50 pm
PTY
-
CLE
2 stops13h 00m
Multiple Airlines
Deal found 1/13$535
This American Airlines deal was found by Cheapflights users on 1/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:04 am
CLE
-
PTY
1 stop7h 32m
American Airlines
Sun 5/101:49 pm
PTY
-
CLE
1 stop9h 09m
American Airlines
Deal found 1/14$536
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/237:04 pm
CLE
-
PTY
1 stop25h 15m
Multiple Airlines
Thu 2/262:55 am
PTY
-
CLE
2 stops15h 14m
Multiple Airlines
Deal found 1/13$541
This Kiwi.com deal was found by Cheapflights users on 1/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/17:04 pm
CLE
-
PTY
1 stop25h 15m
Multiple Airlines
Thu 3/52:55 am
PTY
-
CLE
2 stops22h 47m
Multiple Airlines
Deal found 1/13$544

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
Use the filters below to find and compare flights from Cleveland to Panama City that are best for you.

Fly from

Cleveland

Fly to

Panama City

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 3/29

6:15 am-4:12 pm

1 stop10h 57m

Panama City Tocumen Intl

Thu 4/2

9:45 am-8:48 pm

1 stop10h 03m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 4/2

6:00 am-2:14 pm

1 stop9h 14m

Panama City Tocumen Intl

Fri 4/10

10:00 am-9:59 pm

1 stop10h 59m

$531

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 2/28

7:55 pm-10:30 am

2 stops14h 35m

Panama City Tocumen Intl

Wed 3/11

7:50 pm-9:50 am

2 stops13h 00m

$535

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/23

3:13 pm-8:50 am

2 stops17h 37m

Panama City Tocumen Intl

Sat 2/28

10:26 am-11:21 pm

1 stop12h 55m

$539

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/23

7:04 pm-8:19 pm

1 stop25h 15m

Panama City Tocumen Intl

Thu 2/26

2:55 am-6:09 pm

2 stops15h 14m

$541

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Mon 2/23

6:00 am-2:45 pm

1 stop8h 45m

Panama City Tocumen Intl

Tue 2/24

4:41 pm-11:21 am

1 stop18h 40m

$551

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sat 2/21

2:40 pm-2:00 pm

3 stops23h 20m

$211

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/3

5:43 pm-1:40 pm

2 stops19h 57m

$243

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/3

6:00 am-1:50 pm

1 stop7h 50m

$243

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 1/18

7:01 pm-12:40 am

2 stops29h 39m

$256

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/15

Showing 1-10 of 12 results
1
2

Compare providers for flights from Cleveland to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Cleveland to Panama City in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars
AranGrantPrice Accuracy2 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Cleveland-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Cleveland-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Cleveland-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Cleveland-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Cleveland-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Cleveland to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama City

What is the cheapest month to book a flight from Cleveland to Panama City?

Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $384). Flying from Cleveland to Panama City in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated January 15, 2026.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Cleveland to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,048 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,048 reviews
Delta
7.9
Good
8,048 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,163 reviews
Delta
7.9
Good
8,048 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,129 reviews
Delta
7.9
Good
8,048 reviews

Comfort

7.9

Overall

7.9

Entertainment

7.8

Food

7.2

Boarding

8.1

Crew

8.5

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Panama City?

    There are many flights that can get you from Cleveland to Panama City in 10h 57m. Fly via United Airlines to get the fastest option. Cleveland and Panama City are separated by a distance of 2238 mi.

  • What are the cheapest airlines flying from Cleveland to Panama City round-trip?

    Cheapflights users have booked flights from Cleveland to Panama City round-trip from $389. Other airlines that can offer you cheap pricing are American Airlines, from $390, and United Airlines, from $469. You may be able to fly from Cleveland to Panama City for 32% less than the average price by searching for these airlines.

  • Can I find deals for flights from Cleveland to Panama City that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama City.

  • Can I find deals for business class flights from Cleveland to Panama City?

    Yes. Cheapflights offers flight deals from Cleveland to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama City?

    Currently, November is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $384). Flying from Cleveland to Panama City in August is currently the most expensive (average of $540). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Cleveland to Panama City

Discover the top 3 airlines that operate flights from Cleveland to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$570FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$390Average$644FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$599FlexibilityNo cancel feeOn-time69%

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