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$232+ Cheap flights from Cleveland (CLE) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/3. Fares are subject to change and may not be available on all flights or dates of travel.
CLE — PTY
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Cleveland Hopkins Intl to Panama City Tocumen Intl are usually found in November or September, booked 12 days in advance, depart on a Friday or Wednesday and return on a Wednesday

Cheap flight deals from Cleveland to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Cleveland (CLE) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$484
(Kiwi.com)

One-way from

$232
(Delta)

Popular in

December

Cheapest in

November

Average price

$523
From Cleveland Hopkins Intl to Panama City Tocumen Intl
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One-way flight from Cleveland Hopkins Intl to Panama City Tocumen Intl
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Highest demand for flights based on searches. 5% potential increase in price ($34 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($25 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Cleveland to Panama City

Cheapest flights from Cleveland to Panama City
Explore the most affordable flight options available from Cleveland to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/256:27 pmCLE - PTY
1 stop14h 44mMultiple Airlines
Sat 11/19:33 pmPTY - CLE
2 stops14h 49mMultiple Airlines
Deal found 9/10$484
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:03 amCLE - PTY
1 stop13h 35mUnited Airlines
Fri 12/58:55 amPTY - CLE
1 stop12h 55mUnited Airlines
Deal found 9/10$509
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/151:23 pmCLE - PTY
2 stops24h 26mAmerican Airlines
Wed 11/192:49 pmPTY - CLE
2 stops19h 38mAmerican Airlines
Deal found 9/11$514
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:30 amCLE - PTY
2 stops14h 07mMultiple Airlines
Fri 12/53:39 pmPTY - CLE
1 stop9h 09mMultiple Airlines
Deal found 9/10$515
This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/511:42 amCLE - PTY
1 stop8h 20mUnited Airlines
Sat 12/611:55 pmPTY - CLE
1 stop10h 15mUnited Airlines
Deal found 9/10$529
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/97:36 pmCLE - PTY
2 stops19h 27mAmerican Airlines
Thu 10/163:15 pmPTY - CLE
2 stops20h 02mAmerican Airlines
Deal found 9/10$534
This United Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/116:05 amCLE - PTY
1 stop9h 09mUnited Airlines
Tue 10/1410:00 amPTY - CLE
1 stop12h 13mUnited Airlines
Deal found 9/9$549
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/113:36 pmCLE - PTY
2 stops23h 27mAmerican Airlines
Tue 10/143:15 pmPTY - CLE
2 stops19h 15mAmerican Airlines
Deal found 9/9$554
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/178:53 pmCLE - PTY
2 stops18h 10mAmerican Airlines
Mon 10/203:15 pmPTY - CLE
2 stops20h 43mAmerican Airlines
Deal found 9/11$574
This Kiwi.com deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/2611:56 amCLE - PTY
1 stop8h 24mMultiple Airlines
Sun 11/29:33 pmPTY - CLE
2 stops14h 49mMultiple Airlines
Deal found 9/11$577
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/217:46 pmCLE - PTY
1 stop24h 13mDelta
Tue 11/253:37 pmPTY - CLE
1 stop9h 07mDelta
Deal found 9/10$581

Cheapflights Fare Finder

 
Customize your flight search to find flights from Cleveland to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Cleveland to Panama City that are best for you.

Fly from

Cleveland

Fly to

Panama City

Route

Depart

Return

Price

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Mon 2/2

3:27 pm-12:37 am

1 stop9h 10m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 2/26

6:15 am-7:38 pm

1 stop13h 23m

Panama City Tocumen Intl

Tue 3/3

10:00 am-6:43 pm

1 stop8h 43m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Tue 2/3

3:27 pm-9:15 am

1 stop17h 48m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Wed 3/4

6:15 am-2:45 pm

1 stop8h 30m

Panama City Tocumen Intl

Tue 3/10

10:55 pm-8:42 am

1 stop8h 47m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Tue 3/10

6:15 am-1:45 pm

1 stop8h 30m

Panama City Tocumen Intl

Mon 3/16

10:55 pm-8:42 am

1 stop8h 47m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Thu 1/29

6:00 am-2:02 pm

1 stop8h 02m

Panama City Tocumen Intl

Wed 2/4

3:27 pm-9:15 am

1 stop17h 48m

$489

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 2/1

2:35 pm-2:02 pm

1 stop23h 27m

Panama City Tocumen Intl

Wed 2/4

3:27 pm-9:15 am

1 stop17h 48m

$498

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 2/1

2:35 pm-2:02 pm

1 stop23h 27m

Panama City Tocumen Intl

Thu 2/5

3:27 pm-9:15 am

1 stop17h 48m

$498

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Sun 2/1

2:35 pm-2:02 pm

1 stop23h 27m

Panama City Tocumen Intl

Tue 2/3

3:27 pm-9:15 am

1 stop17h 48m

$498

ClevelandPanama City

CLE - PTY

CLEPTY

Cleveland Hopkins Intl

Fri 2/27

6:15 am-5:07 pm

1 stop10h 52m

Panama City Tocumen Intl

Wed 3/4

10:00 am-6:43 pm

1 stop8h 43m

$509

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/10

Showing 1-10 of 18 results
1
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Best time to book a flight from Cleveland to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Cleveland with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Cleveland to Panama City

How far ahead should I book a flight from Cleveland to Panama City?

Use this chart to determine the optimal time to book a round-trip flight from Cleveland to Panama City. Price data was last updated on August 29, 2025.

To ensure you get the cheapest price possible for a flight from Cleveland to Panama City, you should look to book at least 9 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Cleveland to Panama City?

Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $478). Flying from Cleveland to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from CLE to PTY?

Find hourly flight availability from Cleveland to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 11, 2025.

It’s optimal to fly from Cleveland to Panama City in the morning. By choosing this option you can save up to 20% on the cost of your flight, compared to a flight at noon.

How much does it cost to fly round-trip from Cleveland to Panama City?

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated September 11, 2025.
Peruse reviews from past customers who have flown with Delta, United Airlines, and American Airlines from Cleveland to Panama City to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Food

7.3

Boarding

8.2

Overall

8.0

Entertainment

7.9

Crew

8.5

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Cleveland to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Cleveland to Panama City?

    There are many flights that can get you from Cleveland to Panama City in 8h 02m. Fly via Delta or United Airlines to get the fastest option. Cleveland and Panama City are separated by a distance of 2238 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Cleveland to Panama City round-trip?

    Cheapflights users have booked flights from Cleveland to Panama City round-trip from $389. Other airlines that can offer you cheap pricing are American Airlines, from $469, and United Airlines, from $469. You may be able to fly from Cleveland to Panama City for 36% less than the average price by searching for these airlines.

  • What are the cheapest airlines to fly from Cleveland to Panama City one-way?

    One-way options have recently been found by users for as low as $232 on American Airlines. Other airlines that offer cheap prices include Delta from $232 and United Airlines from $232 one-way.

  • Can I find deals for flights from Cleveland to Panama City that include hotel bookings?

    Yes. In addition to deals on Cleveland to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Cleveland to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Cleveland to Panama City.

  • Can I find deals for business class flights from Cleveland to Panama City?

    Yes. Cheapflights offers flight deals from Cleveland to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Cleveland to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Cleveland to Panama City (average of $478). Flying from Cleveland to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 3 airlines flying from Cleveland to Panama City

Discover the top 3 airlines that operate flights from Cleveland to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$389Average$576FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$469Average$677FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$469Average$614FlexibilityNo cancel feeOn-time69%

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