$317+ Cheap flights from Chicago (CHI) to Panama City (PTY)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/21. Fares are subject to change and may not be available on all flights or dates of travel.
CHI — PTY
Sep 9 — Sep 161
Round-trip
1 adult, Economy
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Find cheap flights from Chicago to Panama City with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Chicago to Panama City Tocumen Intl are usually found in February or May, booked 35 days in advance, depart on a Tuesday or Wednesday and return on a Saturday
Cheap flight deals from Chicago to Panama City
Cheapest
Best
Last-minute
One-way
Cheapest flights from Chicago to Panama CityExplore the most affordable flight options available from Chicago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
Explore the most affordable flight options available from Chicago to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 10, 2026.
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:40 am -
3 stops32h 50m
Wed 9/305:30 am -
3 stops24h 22m
Deal found 8/10![Multiple Airlines logo]()
$700
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:40 am -
3 stops24h 15m
Sun 9/134:25 am -
3 stops25h 27m
Deal found 8/7![Multiple Airlines logo]()
$701
This Mytrip deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:04 am -
3 stops33h 26m
Tue 12/82:55 pm -
3 stops32h 18m
Deal found 8/5![Multiple Airlines logo]()
$708
This Mytrip deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:40 am -
3 stops24h 15m
Sat 10/35:30 am -
3 stops24h 22m
Deal found 8/8![Multiple Airlines logo]()
$709
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:40 am -
3 stops32h 50m
Mon 8/315:55 pm -
3 stops35h 57m
Deal found 8/7![Multiple Airlines logo]()
$711
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:40 am -
3 stops32h 50m
Mon 9/285:30 am -
3 stops24h 22m
Deal found 8/7![Multiple Airlines logo]()
$712
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:11 am -
2 stops17h 24m
Thu 9/244:25 am -
3 stops20h 20m
Deal found 8/8![Multiple Airlines logo]()
$714
This Mytrip deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:40 am -
3 stops31h 35m
Wed 9/165:55 pm -
3 stops35h 57m
Deal found 8/9![Multiple Airlines logo]()
$715
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:35 am -
1 stop12h 39m
Thu 9/2410:25 am -
2 stops19h 27m
Deal found 8/8![Multiple Airlines logo]()
$716
This Mytrip deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:40 am -
3 stops24h 15m
Tue 9/85:30 am -
3 stops24h 22m
Deal found 8/5![Multiple Airlines logo]()
$717
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:40 am -
3 stops32h 50m
Mon 8/315:55 pm -
3 stops35h 57m
Deal found 8/7![Multiple Airlines logo]()
$719
This Mytrip deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:40 am -
3 stops32h 50m
Sun 4/2511:25 am -
2 stops24h 43m
Deal found 8/9![Multiple Airlines logo]()
$723
Best flights from Chicago to Panama CityDiscover carefully curated flight deals from Chicago to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
Discover carefully curated flight deals from Chicago to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 10, 2026.
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
1 stop7h 05m
Wed 12/93:30 pm -
1 stop8h 26m
Deal found 8/6![Delta logo]()
$812
This Copa Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/52:13 pm -
Nonstop5h 24m
Sun 11/158:05 am -
Nonstop5h 41m
Deal found 8/7![Copa Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:30 am -
1 stop12h 01m
Mon 10/510:00 am -
1 stop13h 27m
Deal found 8/9![United Airlines logo]()
$820
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
1 stop7h 05m
Tue 12/83:30 pm -
1 stop8h 26m
Deal found 8/5![Delta logo]()
$812
This Copa Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:35 am -
Nonstop5h 26m
Tue 11/108:05 am -
Nonstop5h 41m
Deal found 8/6![Copa Airlines logo]()
$817
This United Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/97:30 am -
1 stop12h 01m
Mon 10/123:30 pm -
1 stop8h 53m
Deal found 8/7![United Airlines logo]()
$820
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:27 am -
1 stop7h 32m
Tue 11/103:30 pm -
2 stops17h 16m
Deal found 8/6![Delta logo]()
$816
This Copa Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Copa Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:01 am -
Nonstop5h 21m
Mon 10/267:28 pm -
Nonstop5h 37m
Deal found 8/10![Copa Airlines logo]()
$825
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:27 am -
1 stop7h 32m
Sun 10/252:24 pm -
2 stops17h 17m
Deal found 8/5![Delta logo]()
$824
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:27 am -
1 stop7h 32m
Mon 11/93:30 pm -
2 stops17h 16m
Deal found 8/6![Delta logo]()
$824
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:00 am -
1 stop6h 55m
Fri 1/223:20 pm -
1 stop7h 50m
Deal found 8/9![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/146:00 am -
1 stop6h 55m
Sat 1/161:40 pm -
1 stop9h 30m
Deal found 8/9![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop7h 05m
Tue 11/243:30 pm -
1 stop8h 26m
Deal found 8/8![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:00 am -
1 stop6h 55m
Tue 3/23:20 pm -
1 stop7h 50m
Deal found 8/8![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop7h 05m
Mon 11/233:30 pm -
1 stop8h 26m
Deal found 8/8![Delta logo]()
$832
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:04 am -
1 stop6h 55m
Sun 11/153:30 pm -
1 stop8h 26m
Deal found 8/9![Delta logo]()
$840
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:04 am -
1 stop6h 55m
Sun 10/182:24 pm -
1 stop8h 09m
Deal found 8/8![Delta logo]()
$840
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/276:05 am -
1 stop6h 53m
Thu 10/12:23 pm -
1 stop8h 21m
Deal found 8/8![Delta logo]()
$840
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:04 am -
1 stop6h 55m
Sun 10/252:24 pm -
1 stop8h 09m
Deal found 8/9![Delta logo]()
$840
Last-minute flights from Chicago to Panama CityDiscover last-minute flight deals from Chicago to Panama City. Data last updated August 10, 2026 and is based on user searches.
Discover last-minute flight deals from Chicago to Panama City. Data last updated August 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:35 am -
1 stop12h 39m
Thu 9/2410:25 am -
2 stops19h 27m
Deal found 8/8![Multiple Airlines logo]()
$716
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:40 am -
3 stops32h 50m
Mon 8/315:55 pm -
3 stops35h 57m
Deal found 8/7![Multiple Airlines logo]()
$711
This Mytrip deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:40 am -
3 stops32h 50m
Sun 4/2511:25 am -
2 stops24h 43m
Deal found 8/9![Multiple Airlines logo]()
$723
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:40 am -
3 stops32h 50m
Mon 8/315:55 pm -
3 stops35h 57m
Deal found 8/7![Multiple Airlines logo]()
$719
This Mytrip deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:40 am -
3 stops24h 15m
Tue 9/85:30 am -
3 stops24h 22m
Deal found 8/5![Multiple Airlines logo]()
$717
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/51:40 am -
3 stops24h 15m
Sun 9/134:25 am -
3 stops25h 27m
Deal found 8/7![Multiple Airlines logo]()
$701
This Mytrip deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/81:40 am -
3 stops31h 35m
Wed 9/165:55 pm -
3 stops35h 57m
Deal found 8/9![Multiple Airlines logo]()
$715
This Trip.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:11 am -
2 stops17h 24m
Thu 9/244:25 am -
3 stops20h 20m
Deal found 8/8![Multiple Airlines logo]()
$714
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/221:40 am -
3 stops32h 50m
Wed 9/305:30 am -
3 stops24h 22m
Deal found 8/10![Multiple Airlines logo]()
$700
This Mytrip deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/241:40 am -
3 stops32h 50m
Mon 9/285:30 am -
3 stops24h 22m
Deal found 8/7![Multiple Airlines logo]()
$712
This Mytrip deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/261:40 am -
3 stops24h 15m
Sat 10/35:30 am -
3 stops24h 22m
Deal found 8/8![Multiple Airlines logo]()
$709
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:05 am -
1 stop6h 53m
Sun 10/42:23 pm -
1 stop8h 21m
Deal found 8/9![Delta logo]()
$840
One-way flights from Chicago to Panama CitySearch for one-way flight options from Chicago to Panama City. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
Search for one-way flight options from Chicago to Panama City. Find affordable one-way fares based on user searches. Data last updated August 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/211:40 am -
2 stops18h 15m
Deal found 8/10![Multiple Airlines logo]()
$317
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/51:40 am -
2 stops18h 15m
Deal found 8/9![Multiple Airlines logo]()
$322
This Mytrip deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/281:40 am -
3 stops24h 15m
Deal found 8/10![Multiple Airlines logo]()
$332
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:35 am -
1 stop30h 35m
Deal found 8/6![Multiple Airlines logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/177:35 am -
1 stop23h 16m
Deal found 8/6![Multiple Airlines logo]()
$343
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/139:20 am -
2 stops35h 17m
Deal found 8/5![Multiple Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:03 pm -
2 stops20h 27m
Deal found 8/5![Multiple Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/131:40 am -
1 stop12h 30m
Deal found 8/6![Multiple Airlines logo]()
$352
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/1512:03 pm -
2 stops20h 27m
Deal found 8/7![Multiple Airlines logo]()
$375
This Kiwi.com deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:25 am -
3 stops30h 03m
Deal found 8/9![Multiple Airlines logo]()
$376
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:40 am -
2 stops25h 26m
Deal found 8/6![Multiple Airlines logo]()
$389
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/168:23 pm -
2 stops34h 28m
Deal found 8/6![Multiple Airlines logo]()
$408
Find flight deals from Chicago to Panama City
Discover tips and strategies to find the most affordable flight options for your journey from Chicago (CHI) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $700 (Mytrip) |
One-way from | $317 (Kiwi.com) |
Popular in | July |
Cheapest in | February |
Average price | $753 |
Good round-trip deal | $507 or less |
Good one-way deal | $299 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Chicago to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
Use the filters below to find and compare flights from Chicago to Panama City that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Wed 11/18
6:00 am-2:05 pm
1 stop7h 05m
Panama City Tocumen Intl
Wed 12/9
3:30 pm-10:56 pm
1 stop8h 26m
$812
ChicagoPanama City
MDW Chicago Midway - PTY Panama City Tocumen Intl
MDWPTY
Chicago Midway
Fri 12/4
6:00 am-2:05 pm
1 stop7h 05m
Panama City Tocumen Intl
Tue 12/8
3:30 pm-10:56 pm
1 stop8h 26m
$812
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/5
5:27 am-1:59 pm
1 stop7h 32m
Panama City Tocumen Intl
Tue 11/10
3:30 pm-7:46 am
2 stops17h 16m
$816
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/5
2:13 pm-8:37 pm
Nonstop5h 24m
Panama City Tocumen Intl
Sun 11/15
8:05 am-12:46 pm
Nonstop5h 41m
$817
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 11/5
7:35 am-2:01 pm
Nonstop5h 26m
Panama City Tocumen Intl
Tue 11/10
8:05 am-12:46 pm
Nonstop5h 41m
$817
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 10/1
7:30 am-7:31 pm
1 stop12h 01m
Panama City Tocumen Intl
Mon 10/5
10:00 am-11:27 pm
1 stop13h 27m
$820
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Fri 10/9
7:30 am-7:31 pm
1 stop12h 01m
Panama City Tocumen Intl
Mon 10/12
3:30 pm-12:23 am
1 stop8h 53m
$820
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Thu 10/22
5:27 am-12:59 pm
1 stop7h 32m
Panama City Tocumen Intl
Sun 10/25
2:24 pm-7:41 am
2 stops17h 17m
$824
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Mon 11/2
5:27 am-1:59 pm
1 stop7h 32m
Panama City Tocumen Intl
Mon 11/9
3:30 pm-7:46 am
2 stops17h 16m
$824
Quickest round-trip
ChicagoPanama City
ORD Chicago O'Hare Intl - PTY Panama City Tocumen Intl
ORDPTY
Chicago O'Hare Intl
Sun 10/18
8:01 am-1:22 pm
Nonstop5h 21m
Panama City Tocumen Intl
Mon 10/26
7:28 pm-1:05 am
Nonstop5h 37m
$825
Showing 1-10 of 35 resultsSorted by cheapest first
Compare providers for flights from Chicago to Panama City
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Chicago to Panama City in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy- | Trust Score*1 star | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Chicago-Panama City flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Chicago-Panama City flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Chicago-Panama City flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Chicago-Panama City flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Chicago-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Chicago to Panama City
Have a flexible travel schedule? Discover the best time to fly to Panama City from Chicago with our price prediction graph.
CHI-PTY
ORD-PTY
MDW-PTY
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Chicago to Panama City
CHI-PTY
ORD-PTY
MDW-PTY
What is the cheapest month to book a flight from Chicago to Panama City?
Currently, April is the cheapest month in which you can book a flight from Chicago to Panama City (average of $584). Flying from Chicago to Panama City in July is currently the most expensive (average of $778). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from CHI to PTY?
Find hourly flight availability from Chicago to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 10, 2026.
Unlike in the morning, when flights are generally more expensive, you can save up to 17% on flights from Chicago to Panama City by exploring options for tickets in the evening.
Weekly flight availability from Chicago to Panama City
Explore weekly flight availability from Chicago to Panama City. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated August 10, 2026.
The most flights from CHI to PTY are scheduled on a Friday (6 on average). You will have fewer flight options on Thursday, which is when the least amount of flights are scheduled (3 on average).
How much does it cost to fly round-trip from Chicago to Panama City?
Airfare is typical for this route at the moment.
Chicago to Panama City flights typically cost between $587 and $938 in September.The cheapest round-trip price found within the last 5 days was $700 on Multiple Airlines (Sep 22-Sep 30).
How often are flights from Chicago to Panama City delayed?
About 12% of weekly flights between Chicago and Panama City have experienced delays in the past year, with the average delay time being 122 minutes.
What is the most punctual flight time for Chicago to Panama City flights?
Historically, flights departing in the morning are less likely to be delayed, whereas flights leaving at night tend to experience delays more often.
What day of the week experiences the fewest flight delays on this route?
Thursday tends to have the lowest number of delays on this route, whereas Sunday has historically faced a higher average of delays compared to other days of the week.
Which airline has the best punctuality record on Chicago to Panama City flights?
Over the last year, Copa Airlines have had the lowest number of delays on this route, with just 12% of flights being delayed.
How far ahead should I book a flight from Chicago to Panama City?
The price you pay for your flight from Chicago to Panama City may vary depending on when you book. For the best chance of a lower fare, look to book 48 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest day to fly from Chicago to Panama City?
Use this chart to determine the cheapest time to fly round-trip from Chicago to Panama City. Price data was last updated on August 8, 2026.
Travelers seeking maximum savings on their Chicago to Panama City flight should consider departing on Thursday evenings when fares are most often at their lowest. Saturday mornings flights should be avoided if possible as fares are typically the most expensive at this time.
The best insider tips for Chicago to Panama City flights
AI-powered summary based on content written by travel experts. AI can make mistakes.
Cheapflights partnered with top experts to bring you the best recommendations for your Chicago to Panama City trip
Our travel experts
Reviews of airlines servicing Panama City
Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated August 10, 2026.
See what other customers who have flown with Copa Airlines,United Airlines, andAvianca from Chicago to Panama City have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
6.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Entertainment
6.8
Food
6.9
Overall
7.6
Comfort
7.4
Crew
8.1
Boarding
7.8
Reviews
1 / 20
2.0
MediocreAnonymous,Jul 2026
BOS - PTY
Related info for your journey
Find useful and relevant information for your journey from Chicago to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Complete your trip
Complete your trip to Panama City by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Chicago to Panama City by cabin class
Find flights from Chicago to Panama City, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Chicago and Panama City flights
Browse other Chicago and Panama City flight options. Last updated on August 10, 2026.
Other flights from Chicago
Browse through other flights departing from Chicago. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Other flights to Panama City
Explore flights to Panama City departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 4 airlines flying from Chicago to Panama City
Discover the top 4 airlines that operate flights from Chicago to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$264 | Average$302 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$450 | Average$639 | FlexibilityNo cancel fee | On-time70% | |
| Cheapest$577 | Average$764 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$601 | Average$788 | FlexibilityNo cancel fee | On-time71% |