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$509+ Cheap flights from Buffalo (BUF) to Panama City (PTY)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$509
(Delta)

Popular in

December

Cheapest in

April

Average price

$617
Provider with most accurate pricing for Buffalo-Panama City Tocumen Intl flight deals.
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Provider most trusted by Cheapflights users for Buffalo-Panama City Tocumen Intl flights.
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From Buffalo to Panama City Tocumen Intl
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Highest demand for flights based on searches. 8% potential increase in price ($58 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/249:14 amBUF - PTY
2 stops28h 58mDelta
Mon 12/83:46 pmPTY - BUF
2 stops23h 29mDelta
Deal found 10/29$509
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/173:00 pmBUF - PTY
2 stops23h 45mUnited Airlines
Sun 12/214:41 pmPTY - BUF
2 stops24h 13mUnited Airlines
Deal found 10/29$539
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/177:59 pmBUF - PTY
2 stops18h 13mDelta
Mon 12/13:37 pmPTY - BUF
1 stop19h 27mDelta
Deal found 10/29$599
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:34 amBUF - PTY
2 stops10h 08mAmerican Airlines
Wed 12/312:53 pmPTY - BUF
2 stops21h 09mAmerican Airlines
Deal found 10/29$606
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/135:32 pmBUF - PTY
2 stops22h 10mAmerican Airlines
Sat 12/202:53 pmPTY - BUF
2 stops20h 29mAmerican Airlines
Deal found 10/29$618
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/247:30 pmBUF - PTY
2 stops19h 15mUnited Airlines
Mon 12/811:55 pmPTY - BUF
2 stops13h 17mUnited Airlines
Deal found 10/30$663
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/176:32 amBUF - PTY
2 stops31h 17mAmerican Airlines
Mon 12/12:43 pmPTY - BUF
2 stops32h 06mAmerican Airlines
Deal found 10/29$697
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/237:48 pmBUF - PTY
2 stops21h 19mUnited Airlines
Fri 12/2610:00 amPTY - BUF
1 stop8h 34mUnited Airlines
Deal found 10/29$707
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/133:18 pmBUF - PTY
1 stop19h 15mMultiple Airlines
Sat 12/209:40 amPTY - BUF
1 stop11h 10mMultiple Airlines
Deal found 10/29$779

Cheapflights Fare Finder

 
Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Buffalo

Fly to

Panama City

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 11/24

9:14 am-2:12 pm

2 stops28h 58m

Panama City Tocumen Intl

Mon 12/8

3:46 pm-3:15 pm

2 stops23h 29m

$509

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 2/6

6:20 pm-5:10 am

1 stop10h 50m

Panama City Tocumen Intl

Wed 2/11

4:41 pm-1:17 pm

2 stops20h 36m

$522

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Fri 2/6

6:53 pm-3:52 pm

2 stops20h 59m

Panama City Tocumen Intl

Wed 2/11

2:27 pm-10:59 am

2 stops20h 32m

$522

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sat 1/17

11:24 am-8:02 pm

1 stop8h 38m

Panama City Tocumen Intl

Fri 1/23

11:55 pm-8:29 pm

2 stops20h 34m

$522

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 3/16

6:45 pm-4:10 am

1 stop10h 25m

Panama City Tocumen Intl

Sat 3/21

10:55 pm-7:06 pm

2 stops19h 11m

$522

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 12/17

3:00 pm-2:45 pm

2 stops23h 45m

Panama City Tocumen Intl

Sun 12/21

4:41 pm-4:54 pm

2 stops24h 13m

$539

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Compare providers for flights from Buffalo to Panama City

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Buffalo to Panama City in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Buffalo-Panama City flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Buffalo-Panama City flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Buffalo-Panama City flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Buffalo-Panama City flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Buffalo-Panama City flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama City

What is the cheapest month to book a flight from Buffalo to Panama City?

Currently, May is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $240). Flying from Buffalo to Panama City in June is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PTY?

Find hourly flight availability from Buffalo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

It’s optimal to fly from Buffalo to Panama City in the evening. By choosing this option you can save up to 40% on the cost of your flight, compared to a flight at noon.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated October 30, 2025.
Read through reviews of airlines operating flights from Buffalo to Panama City, such as Delta. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
7.9
Good
7,998 reviews
Delta
7.9
Good
7,998 reviews

Food

7.3

Overall

7.9

Entertainment

7.9

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Buffalo to Panama City?

    Delta and United Airlines can get you from Buffalo to Panama City in just under 10h 50m. Your travel time can differ by up to 18h 08m. Airlines will cover a distance of 2339 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What is the cheapest airline to fly from Buffalo to Panama City round-trip?

    Delta, at $486, was found to be the cheapest airline from Buffalo to Panama City.. Delta is currently priced 23% below the average price you’ll pay for this route.

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama City?

    Currently, May is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $240). Flying from Buffalo to Panama City in June is currently the most expensive (average of $638). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Buffalo to Panama City

Discover the top airline that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$486Average$674FlexibilityNo cancel feeOn-timeN/A

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