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Panama City

$222+ Cheap flights from Buffalo (BUF) to Panama City (PTY)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/24. Fares are subject to change and may not be available on all flights or dates of travel.
BUF — PTY
Jul 8 — Jul 151
Tue 7/8
Tue 7/15
1 adult, Economy
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Cheap flight deals from Buffalo to Panama City

Discover tips and strategies to find the most affordable flight options for your journey from Buffalo (BUF) to Panama City (PTY). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated July 3, 2025.

Round-trip from

$517
(Delta)

One-way from

$222
(Delta)

Popular in

March

Cheapest in

April

Average price

$626
From Buffalo to Panama City Tocumen Intl
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One-way flight from Buffalo to Panama City Tocumen Intl
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High demand for flights, 1% potential price rise
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from Buffalo to Panama City

Cheapest flights from Buffalo to Panama City
Explore the most affordable flight options available from Buffalo to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2025.

This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/46:00 amBUF - PTY
1 stop8h 13mDelta
Sat 9/62:05 pmPTY - BUF
1 stop8h 52mDelta
Deal found 7/2$517
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/306:00 amBUF - PTY
1 stop8h 50mUnited Airlines
Wed 9/39:45 amPTY - BUF
1 stop10h 55mUnited Airlines
Deal found 7/2$524
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/37:25 pmBUF - PTY
2 stops19h 50mAmerican Airlines
Fri 9/53:31 pmPTY - BUF
2 stops19h 59mAmerican Airlines
Deal found 7/2$612
This Avianca deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Avianca is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/47:45 pmBUF - PTY
2 stops17h 50mAvianca
Fri 9/53:40 pmPTY - BUF
2 stops26h 21mAvianca
Deal found 7/2$1,061
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/179:07 pmBUF - PTY
1 stop14h 28mMultiple Airlines
Tue 7/2210:05 pmPTY - BUF
2 stops33h 47mMultiple Airlines
Deal found 7/2$1,159

Cheapflights Fare Finder

Customize your flight search to find flights from Buffalo to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
Use the filters below to find and compare flights from Buffalo to Panama City that are best for you.

Fly from

Buffalo

Fly to

Panama City

Route

Depart

Return

Price

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/4

6:00 am-1:13 pm

1 stop8h 13m

Panama City Tocumen Intl

Sat 9/6

2:05 pm-11:57 pm

1 stop8h 52m

$517

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Wed 7/30

6:00 am-1:50 pm

1 stop8h 50m

Panama City Tocumen Intl

Wed 9/3

9:45 am-9:40 pm

1 stop10h 55m

$524

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Sun 8/3

7:25 pm-2:15 pm

2 stops19h 50m

Panama City Tocumen Intl

Fri 9/5

3:31 pm-12:30 pm

2 stops19h 59m

$612

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Mon 8/4

7:45 pm-12:35 pm

2 stops17h 50m

Panama City Tocumen Intl

Fri 9/5

3:40 pm-7:01 pm

2 stops26h 21m

$1,061

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 7/17

9:07 pm-10:35 am

1 stop14h 28m

Panama City Tocumen Intl

Tue 7/22

10:05 pm-8:52 am

2 stops33h 47m

$1,159

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 7/24

7:34 pm-1:13 pm

2 stops18h 39m

$222

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 7/22

5:54 pm-2:14 pm

2 stops21h 20m

$226

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Thu 7/24

9:07 pm-12:45 am

3 stops28h 38m

$352

BuffaloPanama City

BUF - PTY

BUFPTY

Buffalo

Tue 7/22

10:30 am-12:35 pm

3 stops27h 05m

$392

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/2

Best time to book a flight from Buffalo to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from Buffalo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Buffalo to Panama City

What is the cheapest month to book a flight from Buffalo to Panama City?

Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $478). Flying from Buffalo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from BUF to PTY?

Find hourly flight availability from Buffalo to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 3, 2025.

It’s optimal to fly from Buffalo to Panama City in the afternoon. By choosing this option you can save up to 39% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 3, 2025.
Read through reviews of airlines operating flights from Buffalo to Panama City, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Delta
8.0
Very good
7,982 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
United Airlines
7.4
Good
8,861 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.
Avianca
6.7
Okay
2,363 reviews
Delta
8.0
Very good
7,982 reviews

Boarding

8.2

Entertainment

7.9

Crew

8.5

Food

7.3

Overall

8.0

Comfort

7.9

Reviews

1 / 20
10.0
Excellent

Kymberlee,Oct 2024

JFK - ATL

Overall it was good on the flight. Before the flight with checking the bag at JFK was a nightmare. It took way too long and the Delta concierge was very rude to everyone. But other than that it was fine.

Related info for your journey

Find useful and relevant information for your journey from Buffalo to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Buffalo to Panama City round-trip?

    Delta, at $517, was found to be the cheapest airline from Buffalo to Panama City.Alternate airlines to your destination round-trip include United Airlines and American Airlines. Delta is currently priced 14% below the average price you’ll pay for this route.

  • What are the cheapest airlines to fly from Buffalo to Panama City one-way?

    The cheapest airlines for a one-way flight from Buffalo to Panama City are Delta ($222), United Airlines ($226), and Avianca ($392).

  • Can I find deals for flights from Buffalo to Panama City that include hotel bookings?

    Yes. In addition to deals on Buffalo to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Buffalo to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Buffalo to Panama City.

  • Can I find deals for business class flights from Buffalo to Panama City?

    Yes. Cheapflights offers flight deals from Buffalo to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Buffalo to Panama City?

    Currently, October is the cheapest month in which you can book a flight from Buffalo to Panama City (average of $478). Flying from Buffalo to Panama City in December is currently the most expensive (average of $634). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Buffalo to Panama City

Discover the top 2 airlines that operate flights from Buffalo to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$441Average$491FlexibilityNo cancel feeOn-time69%
DeltaCheapest$445Average$666FlexibilityNo cancel feeOn-timeN/A

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