How popular is this St. Louis to Panama City, Florida flight route?

The Lambert-St Louis to Panama City NW Florida Beaches flight path was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.

What are the cheapest airlines flying from St. Louis to Panama City, Florida round-trip?

Our cheapest airline available from St. Louis to Panama City, Florida is American Airlines. Our recent data shows that you can find tickets from as low as $211 on this airline. Additional options worth looking into are Delta and Southwest, starting at $221 and $251 round-trip. American Airlines is priced at 48% lower than the current average price of a flight leaving 3 months from now.

What are the cheapest airlines to fly from St. Louis to Panama City, Florida one-way?

The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $96. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from St. Louis to Panama City, Florida for a low price.

What are the cheapest flights from St. Louis to Panama City, Florida?

While on average a flight from St. Louis to Panama City, Florida is generally $394, our data shows the cheapest flight currently is $241. When looking at the most popular route, (Lambert-St Louis - Panama City NW Florida Beaches), you can expect to pay $221 for that flight.

What are the most popular airlines that fly from St. Louis to Panama City, Florida?

Consider American Airlines, Delta or Allegiant Air when booking your flight. These represent the most popular airlines when flying from St. Louis to Panama City, Florida.

What is the cheapest day to fly round-trip from St. Louis to Panama City, Florida?

Users have found that leaving on a Monday can be a cost-effective option. It’s possible to save up to 50% on your flight compared to booking on days when demand is much higher.

How far in advance should I book a flight from St. Louis to Panama City, Florida?

Travelers have found it’s best to book a flight 51 days in advance to save up to 72% compared to booking the same week of travel. As your travel date approaches, the cost of this flight route may potentially increase. While opting to book 51 days out may not be an option for all, there are still additional ways to secure a deal in the near future. You might find a flight from St. Louis to Panama City, Florida 1-2 weeks in advance for as low as $340, or $380 for flights within the next 24 hours.

What is the cheapest month to fly from St. Louis to Panama City, Florida?

The best pricing can be found in the month of September. Prices to Panama City, Florida from St. Louis average $414. You can even find prices in September for less than $414, as users have found deals to Panama City, Florida from as low as $193. The month of November appears to be one of the more expensive times to travel to Panama City, Florida from St. Louis. Flying in the targeted month can save you up to 17%.

Can I find deals for flights from St. Louis to Panama City that include hotel bookings?

Yes. In addition to deals on St. Louis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from St. Louis to Panama City?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama City.

Can I find deals for business class flights from St. Louis to Panama City?

Yes. Cheapflights offers flight deals from St. Louis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$96+ Flights from St. Louis to Panama City, FL

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1. Tell us where you want to go

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We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheapflights Tip: The best prices from Lambert-St Louis to Panama City NW Florida Beaches are usually found in September or July, booked 50 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from St. Louis to Panama City

Round-trip from	$211 (American Airlines)
One-way from	$96 (American Airlines)
Popular in	November
Cheapest in	September
Average price	$386
Good round-trip deal	$291 or less

From Lambert-St Louis to Panama City NW Florida Beaches

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One-way flight from Lambert-St Louis to Panama City NW Florida Beaches

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Highest demand for flights based on searches. 5% potential increase in price ($22 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).

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Average for round-trip flights in June 2025

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Price to beat on a round-trip flight from Lambert-St Louis to Panama City NW Florida Beaches.

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Find flight deals from St. Louis to Panama City

Cheapest flights from St. Louis to Panama City
Explore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

vie. 7/254:28 pmSTL - ECP

1 stop7h 25mAmerican Airlines

jue. 7/316:55 pmECP - STL

1 stop5h 04mAmerican Airlines

Deal found 6/10

$211

lun. 7/75:23 pmSTL - ECP

1 stop5h 58mDelta

jue. 7/102:52 pmECP - STL

1 stop6h 42mDelta

Deal found 6/11

$221

mar. 7/227:50 pmSTL - ECP

Nonstop1h 45mSouthwest

vie. 7/256:15 amECP - STL

1 stop6h 05mSouthwest

Deal found 6/11

$251

jue. 8/1411:25 amSTL - ECP

2 stops10h 35mUnited Airlines

jue. 8/215:06 pmECP - STL

1 stop5h 02mUnited Airlines

Deal found 6/11

$338

Best flights from St. Louis to Panama City
Discover carefully curated flight deals from St. Louis to Panama City that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated junio 12, 2025.

vie. 7/254:28 pmSTL - ECP

1 stop7h 25mAmerican Airlines

jue. 7/316:55 pmECP - STL

1 stop5h 04mAmerican Airlines

Deal found 6/10

$211

lun. 7/75:23 pmSTL - ECP

1 stop5h 58mDelta

jue. 7/102:52 pmECP - STL

1 stop6h 42mDelta

Deal found 6/11

$221

mar. 7/227:50 pmSTL - ECP

Nonstop1h 45mSouthwest

vie. 7/256:15 amECP - STL

1 stop6h 05mSouthwest

Deal found 6/11

$251

jue. 8/1411:25 amSTL - ECP

2 stops10h 35mUnited Airlines

jue. 8/215:06 pmECP - STL

1 stop5h 02mUnited Airlines

Deal found 6/11

$338

Last-minute flights from St. Louis to Panama City
Discover last-minute flight deals from St. Louis to Panama City. Data last updated junio 12, 2025 and is based on user searches.

mié. 6/186:30 amSTL - ECP

2 stops12h 41mUnited Airlines

lun. 6/233:20 pmECP - STL

1 stop6h 55mUnited Airlines

Deal found 6/9

$563

vie. 6/205:37 amSTL - ECP

1 stop5h 39mAmerican Airlines

mar. 6/247:02 pmECP - STL

1 stop4h 57mAmerican Airlines

Deal found 6/10

$370

vie. 6/209:28 amSTL - ECP

1 stop6h 42mDelta

mar. 6/244:55 pmECP - STL

1 stop6h 41mDelta

Deal found 6/10

$435

sáb. 6/217:15 pmSTL - ECP

Nonstop1h 45mSouthwest

mar. 6/246:05 amECP - STL

Nonstop1h 50mSouthwest

Deal found 6/11

$410

lun. 7/75:23 pmSTL - ECP

1 stop5h 58mDelta

jue. 7/102:52 pmECP - STL

1 stop6h 42mDelta

Deal found 6/11

$221

lun. 7/78:00 amSTL - ECP

1 stop5h 23mUnited Airlines

jue. 7/1011:10 amECP - STL

2 stops11h 35mUnited Airlines

Deal found 6/11

$476

mar. 7/227:50 pmSTL - ECP

Nonstop1h 45mSouthwest

vie. 7/256:15 amECP - STL

1 stop6h 05mSouthwest

Deal found 6/11

$251

vie. 7/254:28 pmSTL - ECP

1 stop7h 25mAmerican Airlines

jue. 7/316:55 pmECP - STL

1 stop5h 04mAmerican Airlines

Deal found 6/10

$211

One-way flights from St. Louis to Panama City
Search for one-way flight options from St. Louis to Panama City. Find affordable one-way fares based on user searches. Data last updated junio 12, 2025.

lun. 7/146:10 amSTL - ECP

1 stop6h 43mAmerican Airlines

Deal found 6/10

$96

mar. 7/297:50 pmSTL - ECP

Nonstop1h 45mSouthwest

Deal found 6/11

$101

lun. 7/77:11 pmSTL - ECP

1 stop4h 10mDelta

Deal found 6/11

$111

mié. 8/276:35 amSTL - ECP

2 stops7h 49mUnited Airlines

Deal found 6/10

$207

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Panama City that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

vie. 7/25

4:28 pm-11:53 pm

1 stop7h 25m

Panama City NW Florida Beaches

jue. 7/31

6:55 pm-11:59 pm

1 stop5h 04m

$211

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

lun. 7/7

5:23 pm-11:21 pm

1 stop5h 58m

Panama City NW Florida Beaches

jue. 7/10

2:52 pm-9:34 pm

1 stop6h 42m

$221

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

mar. 7/22

7:50 pm-9:35 pm

Nonstop1h 45m

Panama City NW Florida Beaches

vie. 7/25

6:15 am-12:20 pm

1 stop6h 05m

$251

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

jue. 8/14

11:25 am-10:00 pm

2 stops10h 35m

Panama City NW Florida Beaches

jue. 8/21

5:06 pm-10:08 pm

1 stop5h 02m

$338

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

lun. 7/14

6:10 am-12:53 pm

1 stop6h 43m

$96

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

mar. 7/29

7:50 pm-9:35 pm

Nonstop1h 45m

$101

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

lun. 7/7

7:11 pm-11:21 pm

1 stop4h 10m

$111

St. LouisPanama City

STL - ECP

STLECP

Lambert-St Louis

mié. 8/27

6:35 am-2:24 pm

2 stops7h 49m

$207

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/10

Best time to book a flight from St. Louis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from St. Louis with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Panama City

How far ahead should I book a flight from St. Louis to Panama City, Florida?

The price you pay for your flight from St. Louis to Panama City, Florida may vary depending on when you book. For the best chance of a lower fare, look to book 50 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.

What is the cheapest month to book a flight from St. Louis to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from St. Louis to Panama City, Florida (average of $346). Flying from St. Louis to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from STL to ECP?

It’s typically best to fly out from St. Louis to Panama City, Florida in the morning. Doing so could potentially save you 3% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from St. Louis to Panama City, Florida?

Travelers seeking maximum savings on their St. Louis to Panama City, Florida flight should consider departing on Tuesday at noon when fares are most often at their lowest. Friday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Panama City by month

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

To help decide which airline to fly from St. Louis to Panama City, see what other customers have to say about Southwest, Delta and United Airlines. In addition to providing an overall rating, users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Southwest

8.0

Very good

4,287 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Delta

8.0

Very good

7,950 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

United Airlines

7.4

Good

8,790 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

American Airlines

7.2

Good

10,000 reviews

Southwest

8.0

Very good

4,287 reviews

Reviews

1 / 20

8.0

Excellent

John,May 2025

PVD - BNA

It’s southwest so no frills but clean, efficient and got me to my location.

Related info for your journey

How popular is this St. Louis to Panama City, Florida flight route?
The Lambert-St Louis to Panama City NW Florida Beaches flight path was viewed by 4 users in the past month. Keep an eye out for changes in search interest prior to high and low season.
What are the cheapest airlines flying from St. Louis to Panama City, Florida round-trip?
Our cheapest airline available from St. Louis to Panama City, Florida is American Airlines. Our recent data shows that you can find tickets from as low as $211 on this airline. Additional options worth looking into are Delta and Southwest, starting at $221 and $251 round-trip. American Airlines is priced at 48% lower than the current average price of a flight leaving 3 months from now.
What are the cheapest airlines to fly from St. Louis to Panama City, Florida one-way?
The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $96. However, be on the lookout for offers from Southwest and Delta, as they are both options that can get you from St. Louis to Panama City, Florida for a low price.
What are the cheapest flights from St. Louis to Panama City, Florida?
While on average a flight from St. Louis to Panama City, Florida is generally $394, our data shows the cheapest flight currently is $241. When looking at the most popular route, (Lambert-St Louis - Panama City NW Florida Beaches), you can expect to pay $221 for that flight.
Can I find deals for flights from St. Louis to Panama City that include hotel bookings?
Yes. In addition to deals on St. Louis to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from St. Louis to Panama City?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from St. Louis to Panama City.
Can I find deals for business class flights from St. Louis to Panama City?
Yes. Cheapflights offers flight deals from St. Louis to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from St. Louis to Panama City, Florida?
Currently, January is the cheapest month in which you can book a flight from St. Louis to Panama City, Florida (average of $346). Flying from St. Louis to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 5 airlines flying from St. Louis to Panama City

Airline	Cheapest	Average	Flexibility	On-time
Allegiant Air	Cheapest$192	Average$233	FlexibilityNo cancel fee	On-time88%
American Airlines	Cheapest$215	Average$351	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$240	Average$404	FlexibilityNo cancel fee	On-timeN/A
United Airlines	Cheapest$282	Average$435	FlexibilityNo cancel fee	On-time69%
Southwest	Cheapest$314	Average$448	FlexibilityNo cancel fee	On-time63%

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$96+ Cheap flights from St. Louis to Panama City, FL (STL - ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/14. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from St. Louis to Panama City with Cheapflights

1. Tell us where you want to go

2. Select your favorite providers

3. Compare prices and book

Cheapflights Tip: The best prices from Lambert-St Louis to Panama City NW Florida Beaches are usually found in September or July, booked 50 days in advance, depart on a Tuesday or Monday and return on a Wednesday

Cheap flight deals from St. Louis to Panama City

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Find flight deals from St. Louis to Panama City

Cheapest flights from St. Louis to Panama CityExplore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Explore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from St. Louis to Panama City that are best for you.

Best time to book a flight from St. Louis to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from St. Louis with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from St. Louis to Panama City

How far ahead should I book a flight from St. Louis to Panama City, Florida?

Use this chart to determine the optimal time to book a round-trip flight from St. Louis to Panama City. Price data was last updated on June 9, 2025.

What is the cheapest month to book a flight from St. Louis to Panama City, Florida?

What is the cheapest time of day to fly from STL to ECP?

Find hourly flight availability from St. Louis to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated junio 12, 2025.

What is the cheapest day to fly from St. Louis to Panama City, Florida?

Use this chart to determine the cheapest time to fly round-trip from St. Louis to Panama City. Price data was last updated on June 8, 2025.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

Reviews of airlines servicing Panama City

Related info for your journey

Find useful and relevant information for your journey from St. Louis to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this St. Louis to Panama City, Florida flight route?

What are the cheapest airlines flying from St. Louis to Panama City, Florida round-trip?

What are the cheapest airlines to fly from St. Louis to Panama City, Florida one-way?

What are the cheapest flights from St. Louis to Panama City, Florida?

Can I find deals for flights from St. Louis to Panama City that include hotel bookings?

How can I find direct flights from St. Louis to Panama City?

Can I find deals for business class flights from St. Louis to Panama City?

What is the cheapest month to book a flight from St. Louis to Panama City, Florida?

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Alternative routes for St. Louis to Panama City

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Top 5 airlines flying from St. Louis to Panama City

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Cheapest flights from St. Louis to Panama City
Explore the most affordable flight options available from St. Louis to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on junio 12, 2025.