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Panama City

$127+ Cheap flights from South Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
May 5 — May 121
Mon 5/5
Mon 5/12
1 adult, Economy
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Cheap flight deals from South Carolina to Panama City

Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated April 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$255
(Delta)

One-way from

$127
(Southwest)

Popular in

May

Cheapest in

September

Average price

$506
Provider with most accurate pricing for Myrtle Beach Intl-Panama City NW Florida Beaches flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Panama City NW Florida Beaches flights.
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From South Carolina to Panama City NW Florida Beaches
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One-way flight from South Carolina to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 21% potential increase in price ($101 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($23 potential savings vs. average RT price).
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Average for round-trip flights in April 2025
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Find flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2025.

This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/137:55 pmGSP - ECP
1 stop3h 48mDelta
Sat 9/204:10 pmECP - GSP
1 stop4h 11mDelta
Deal found 4/29$255
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/273:40 pmCLT - ECP
1 stop5h 55mSouthwest
Tue 6/32:55 pmECP - CLT
1 stop5h 25mSouthwest
Deal found 4/29$268
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/136:00 amMYR - ECP
1 stop5h 13mDelta
Sun 8/176:00 amECP - MYR
1 stop3h 11mDelta
Deal found 4/28$268
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/295:35 amCHS - ECP
1 stop3h 41mDelta
Sun 6/17:15 amECP - CHS
1 stop3h 02mDelta
Deal found 4/29$272
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/135:45 amAGS - ECP
1 stop5h 28mDelta
Tue 8/196:00 amECP - AGS
1 stop4h 00mDelta
Deal found 4/28$279
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1110:25 amMYR - ECP
2 stops13h 35mSouthwest
Mon 7/147:00 amECP - MYR
1 stop3h 55mSouthwest
Deal found 4/28$304
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/276:34 amCHS - ECP
1 stop6h 21mAmerican Airlines
Tue 6/312:25 pmECP - CHS
2 stops9h 35mAmerican Airlines
Deal found 4/28$305
This American Airlines deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/319:00 amCLT - ECP
Nonstop1h 48mAmerican Airlines
Sat 6/75:30 amECP - CLT
Nonstop1h 38mAmerican Airlines
Deal found 4/29$313
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/316:35 pmCLT - ECP
1 stop3h 44mDelta
Sat 6/77:15 amECP - CLT
1 stop5h 25mDelta
Deal found 4/29$333
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/305:55 pmCAE - ECP
1 stop2h 53mDelta
Sun 6/19:12 amECP - CAE
1 stop2h 46mDelta
Deal found 4/28$347
This American Airlines deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1311:10 amCAE - ECP
1 stop3h 39mAmerican Airlines
Sat 5/172:29 pmECP - CAE
1 stop6h 25mAmerican Airlines
Deal found 4/28$395
This Southwest deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/301:50 pmGSP - ECP
2 stops9h 15mSouthwest
Sun 6/110:10 amECP - GSP
1 stop5h 15mSouthwest
Deal found 4/28$402

Cheapflights Fare Finder

Customize your flight search to find flights from South Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

South Carolina

Fly to

Panama City

Route

Depart

Return

Price

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Sat 9/13

7:55 pm-10:43 pm

1 stop3h 48m

Panama City NW Florida Beaches

Sat 9/20

4:10 pm-9:21 pm

1 stop4h 11m

$255

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Tue 5/27

3:40 pm-8:35 pm

1 stop5h 55m

Panama City NW Florida Beaches

Tue 6/3

2:55 pm-9:20 pm

1 stop5h 25m

$268

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Wed 8/13

6:00 am-10:13 am

1 stop5h 13m

Panama City NW Florida Beaches

Sun 8/17

6:00 am-10:11 am

1 stop3h 11m

$268

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Thu 5/29

5:35 am-8:16 am

1 stop3h 41m

Panama City NW Florida Beaches

Sun 6/1

7:15 am-11:17 am

1 stop3h 02m

$272

AugustaPanama City

AGS - ECP

AGSECP

Augusta Bush Field

Wed 8/13

5:45 am-10:13 am

1 stop5h 28m

Panama City NW Florida Beaches

Tue 8/19

6:00 am-11:00 am

1 stop4h 00m

$279

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Fri 7/11

10:25 am-11:00 pm

2 stops13h 35m

Panama City NW Florida Beaches

Mon 7/14

7:00 am-11:55 am

1 stop3h 55m

$304

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Tue 5/27

6:34 am-11:55 am

1 stop6h 21m

Panama City NW Florida Beaches

Tue 6/3

12:25 pm-11:00 pm

2 stops9h 35m

$305

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Sat 5/31

9:00 am-9:48 am

Nonstop1h 48m

Panama City NW Florida Beaches

Sat 6/7

5:30 am-8:08 am

Nonstop1h 38m

$313

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Sat 5/31

6:35 pm-9:19 pm

1 stop3h 44m

Panama City NW Florida Beaches

Sat 6/7

7:15 am-1:40 pm

1 stop5h 25m

$333

ColumbiaPanama City

CAE - ECP

CAEECP

Columbia Metropolitan

Fri 5/30

5:55 pm-7:48 pm

1 stop2h 53m

Panama City NW Florida Beaches

Sun 6/1

9:12 am-12:58 pm

1 stop2h 46m

$347

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/29

Showing 1-10 of 29 results
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Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Panama City

What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ECP?

Find hourly flight availability from South Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Panama City, Florida as you normally would.

Rainfall in Panama City by month

Plan your trip to Panama City by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Panama City, Florida ranges from 2.8 - 7.9 inches per month. July is typically the wettest month, when rainfall can reach 7.9 in. May is typically the driest time to visit Panama City, Florida when rainfall is around 2.8 in.

Temperature in Panama City by month

Plan your trip to Panama City by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Panama City, Florida, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 53.6 F).

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated April 30, 2025.
Read reviews from past customers who have flown Southwest, Delta and United Airlines from South Carolina to Panama City. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.0

Crew

8.6

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Southwest
8.0
Very good
4,295 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.0

Crew

8.6

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
Delta
8.0
Very good
7,936 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.0

Crew

8.6

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
United Airlines
7.4
Good
8,696 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.0

Crew

8.6

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,295 reviews

Entertainment

7.6

Boarding

8.2

Overall

8.0

Crew

8.6

Food

7.1

Comfort

8.0

Reviews

1 / 20
10.0
Excellent

Gina,Apr 2025

LAS - DEN

Good, the crew was friendly and helpful. The pilot had great skills in keeping the plane stable through rough turbulence. Smooth landing, too! Thank you!

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Carolina?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Carolina to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • What are the cheapest airlines to fly from South Carolina to Panama City, Florida one-way?

    $127 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on Delta and American Airlines, with prices starting from $128 and $147, respectively.

  • What are the most popular routes from South Carolina to Panama City, Florida?

    While some choose either Charleston - Panama City NW Florida Beaches or Greenville - Panama City NW Florida Beaches, Charlotte Douglas - Panama City NW Florida Beaches is the most popular route from South Carolina to Panama City, Florida.

  • Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.

  • Can I find deals for business class flights from South Carolina to Panama City?

    Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $461). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near South Carolina?

Book flights to South Carolina if you plan to visit one of these locations
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Top 3 airlines flying from South Carolina to Panama City

Discover the top 3 airlines that operate flights from South Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$102Average$406FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$214Average$339FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$413FlexibilityNo cancel feeOn-time63%

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