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Panama City

$98+ Cheap flights from South Carolina to Panama City, FL (ECP)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/28. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — ECP
Aug 4 — Aug 111
Mon 8/4
Mon 8/11
1 adult, Economy
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Cheap flight deals from South Carolina to Panama City

Keep the following information in mind while searching for South Carolina to Panama City flight deals. Data was last updated July 30, 2025.

Round-trip from

$197
(Delta)

One-way from

$98
(Southwest)

Popular in

March

Cheapest in

September

Average price

$476
From South Carolina to Panama City NW Florida Beaches
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One-way flight from South Carolina to Panama City NW Florida Beaches
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Highest demand for flights based on searches. 27% potential increase in price ($135 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($19 potential savings vs. average RT price).
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Average for round-trip flights in July 2025
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Find flight deals from South Carolina to Panama City

Cheapest flights from South Carolina to Panama City
Explore the most affordable flight options available from South Carolina to Panama City. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 30, 2025.

This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/206:20 amCHS - ECP
1 stop2h 59mDelta
Wed 8/277:10 amECP - CHS
1 stop3h 40mDelta
Deal found 7/30$197
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:00 amMYR - ECP
1 stop5h 19mDelta
Wed 10/297:10 amECP - MYR
1 stop5h 40mDelta
Deal found 7/28$197
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/205:33 pmCHS - ECP
1 stop5h 36mAmerican Airlines
Wed 8/2712:06 pmECP - CHS
2 stops10h 53mAmerican Airlines
Deal found 7/30$202
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/106:30 amCLT - ECP
2 stops10h 10mSouthwest
Tue 9/167:40 amECP - CLT
2 stops9h 20mSouthwest
Deal found 7/29$242
This Delta deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/225:30 amGSP - ECP
1 stop4h 14mDelta
Mon 10/276:17 pmECP - GSP
1 stop4h 37mDelta
Deal found 7/30$242
This American Airlines deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/255:59 pmMYR - ECP
1 stop6h 45mAmerican Airlines
Tue 10/286:49 amECP - MYR
1 stop3h 37mAmerican Airlines
Deal found 7/28$257
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1811:07 amAGS - ECP
1 stop5h 35mDelta
Tue 10/216:00 amECP - AGS
1 stop3h 27mDelta
Deal found 7/28$259
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/301:09 pmCAE - ECP
1 stop6h 05mAmerican Airlines
Sun 8/315:30 amECP - CAE
1 stop4h 17mAmerican Airlines
Deal found 7/30$288
This Southwest deal was found by Cheapflights users on 7/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/196:30 amMYR - ECP
2 stops10h 10mSouthwest
Thu 8/2110:40 amECP - MYR
1 stop8h 10mSouthwest
Deal found 7/29$290
This Delta deal was found by Cheapflights users on 7/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/121:15 pmCAE - ECP
1 stop3h 05mDelta
Sat 10/186:00 amECP - CAE
1 stop5h 30mDelta
Deal found 7/28$292
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/177:15 pmGSP - ECP
1 stop5h 26mAmerican Airlines
Sat 8/237:06 pmECP - GSP
1 stop3h 51mAmerican Airlines
Deal found 7/30$294
This American Airlines deal was found by Cheapflights users on 7/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:50 pmCLT - ECP
Nonstop1h 54mAmerican Airlines
Tue 10/216:49 amECP - CLT
Nonstop1h 46mAmerican Airlines
Deal found 7/30$313

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Panama City that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
Use the filters below to find and compare flights from South Carolina to Panama City that are best for you.

Fly from

South Carolina

Fly to

Panama City

Route

Depart

Return

Price

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Wed 8/20

6:20 am-8:19 am

1 stop2h 59m

Panama City NW Florida Beaches

Wed 8/27

7:10 am-11:50 am

1 stop3h 40m

$197

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 10/21

6:00 am-8:44 am

1 stop3h 44m

Panama City NW Florida Beaches

Tue 10/28

5:00 pm-11:59 pm

1 stop5h 59m

$197

CharlestonPanama City

CHS - ECP

CHSECP

Charleston

Wed 8/20

5:33 pm-10:09 pm

1 stop5h 36m

Panama City NW Florida Beaches

Wed 8/27

12:06 pm-11:59 pm

2 stops10h 53m

$202

CharlottePanama City

CLT - ECP

CLTECP

Charlotte Douglas

Wed 9/10

6:30 am-3:40 pm

2 stops10h 10m

Panama City NW Florida Beaches

Tue 9/16

7:40 am-4:35 pm

1 stop7h 55m

$242

GreenvillePanama City

GSP - ECP

GSPECP

Greenville

Wed 10/22

5:30 am-8:44 am

1 stop4h 14m

Panama City NW Florida Beaches

Mon 10/27

6:17 pm-11:54 pm

1 stop4h 37m

$242

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Sat 10/25

5:59 pm-11:44 pm

1 stop6h 45m

Panama City NW Florida Beaches

Tue 10/28

6:49 am-11:26 am

1 stop3h 37m

$257

AugustaPanama City

AGS - ECP

AGSECP

Augusta Bush Field

Sat 10/18

11:07 am-3:42 pm

1 stop5h 35m

Panama City NW Florida Beaches

Tue 10/21

6:00 am-10:27 am

1 stop3h 27m

$259

ColumbiaPanama City

CAE - ECP

CAEECP

Columbia Metropolitan

Sat 8/30

1:09 pm-6:14 pm

1 stop6h 05m

Panama City NW Florida Beaches

Sun 8/31

5:30 am-10:47 am

1 stop4h 17m

$288

Myrtle BeachPanama City

MYR - ECP

MYRECP

Myrtle Beach Intl

Tue 8/19

6:30 am-3:40 pm

2 stops10h 10m

Panama City NW Florida Beaches

Thu 8/21

10:40 am-7:50 pm

1 stop8h 10m

$290

ColumbiaPanama City

CAE - ECP

CAEECP

Columbia Metropolitan

Sun 10/12

1:15 pm-3:20 pm

1 stop3h 05m

Panama City NW Florida Beaches

Sat 10/18

6:00 am-12:30 pm

1 stop5h 30m

$292

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/29

Showing 1-10 of 32 results
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Best time to book a flight from South Carolina to Panama City

Have a flexible travel schedule? Discover the best time to fly to Panama City from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Panama City

What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to ECP?

Find hourly flight availability from South Carolina to Panama City. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 30, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Panama City, Florida as you normally would.

Reviews of airlines servicing Panama City

Get insights into the airlines that provide service to Panama City. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Panama City. Reviews last updated July 30, 2025.
Read through reviews of airlines operating flights from South Carolina to Panama City, such as Southwest, Delta, and United Airlines. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Southwest
8.0
Very good
4,241 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
Delta
8.0
Very good
7,980 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
United Airlines
7.4
Good
8,896 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
American Airlines
7.2
Good
10,000 reviews
Southwest
8.0
Very good
4,241 reviews

Boarding

8.1

Crew

8.6

Food

7.0

Overall

8.0

Comfort

8.0

Entertainment

7.5

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Panama City. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Panama City from South Carolina?

    Panama City NW Florida Beaches (ECP) is the airport you will fly into if you book a flight from South Carolina to Panama City. It is only a 16.0 mi journey from NW Florida Beaches (ECP) to Panama City’s city center.

  • What are the cheapest airlines to fly from South Carolina to Panama City, Florida one-way?

    $98 is the cheapest one-way deal found within the past few days, from Southwest. You may also be able to find cheap deals on American Airlines and Delta, with prices starting from $99 and $110, respectively.

  • What are the most popular routes from South Carolina to Panama City, Florida?

    While some choose either Greenville - Panama City NW Florida Beaches or Columbia Metropolitan - Panama City NW Florida Beaches, Charlotte Douglas - Panama City NW Florida Beaches is the most popular route from South Carolina to Panama City, Florida.

  • Can I find deals for flights from South Carolina to Panama City that include hotel bookings?

    Yes. In addition to deals on South Carolina to Panama City flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Panama City?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Panama City.

  • Can I find deals for business class flights from South Carolina to Panama City?

    Yes. Cheapflights offers flight deals from South Carolina to Panama City by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Panama City, Florida?

    Currently, January is the cheapest month in which you can book a flight from South Carolina to Panama City, Florida (average of $346). Flying from South Carolina to Panama City, Florida in March is currently the most expensive (average of $460). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Panama City?

Book flights to Panama City if you plan to visit one of these locations
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Alternative routes for South Carolina to Panama City

See prices for flight routes from nearby airports that may be better suited for you.
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Top 3 airlines flying from South Carolina to Panama City

Discover the top 3 airlines that operate flights from South Carolina to Panama City. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$102Average$397FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$359FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$301Average$448FlexibilityNo cancel feeOn-time63%

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