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$48+ Cheap flights from Santa Ana, CA (SNA) to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/25. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — STL
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Santa Ana to Missouri

Cheapest flights from Santa Ana to Missouri
Explore the most affordable flight options available from Santa Ana to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This CheapOair deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:37 pm
SNA
-
MCI
1 stop4h 56m
Spirit Airlines
Sat 2/287:00 am
MCI
-
SNA
1 stop7h 25m
Spirit Airlines
Deal found 1/26$185
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/194:37 pm
SNA
-
MCI
1 stop4h 56m
Spirit Airlines
Wed 2/257:00 am
MCI
-
SNA
1 stop10h 42m
Spirit Airlines
Deal found 1/27$195
This Expedia deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/201:20 pm
SNA
-
MCI
1 stop8h 13m
Spirit Airlines
Wed 2/257:00 am
MCI
-
SNA
1 stop10h 42m
Spirit Airlines
Deal found 1/28$197
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/274:37 pm
SNA
-
MCI
1 stop4h 56m
Spirit Airlines
Sat 2/287:00 am
MCI
-
SNA
1 stop7h 25m
Spirit Airlines
Deal found 1/27$201
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/104:37 pm
SNA
-
MCI
1 stop4h 56m
Spirit Airlines
Wed 3/117:00 am
MCI
-
SNA
1 stop7h 25m
Spirit Airlines
Deal found 1/28$202
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/65:07 pm
SNA
-
STL
2 stops14h 42m
Multiple Airlines
Mon 3/912:14 pm
STL
-
SNA
1 stop10h 43m
Multiple Airlines
Deal found 1/28$207
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:37 pm
SNA
-
MCI
1 stop4h 54m
Spirit Airlines
Tue 4/77:00 am
MCI
-
SNA
1 stop7h 22m
Spirit Airlines
Deal found 1/28$212
This Cheapflightsfares deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:37 pm
SNA
-
MCI
1 stop4h 56m
Spirit Airlines
Sat 5/167:00 am
MCI
-
SNA
1 stop10h 42m
Spirit Airlines
Deal found 1/27$217
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/56:45 am
SNA
-
STL
1 stop12h 21m
Multiple Airlines
Sun 2/89:32 pm
STL
-
SNA
1 stop22h 29m
Multiple Airlines
Deal found 1/28$225
This CheapOair deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/244:37 pm
SNA
-
MCI
1 stop4h 54m
Spirit Airlines
Sat 3/287:00 am
MCI
-
SNA
1 stop10h 38m
Spirit Airlines
Deal found 1/27$227
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:20 pm
SNA
-
MCI
1 stop8h 11m
Spirit Airlines
Mon 4/137:00 am
MCI
-
SNA
1 stop7h 22m
Spirit Airlines
Deal found 1/28$229
This CheapOair deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:20 pm
SNA
-
MCI
1 stop8h 11m
Spirit Airlines
Sat 4/47:00 am
MCI
-
SNA
1 stop7h 22m
Spirit Airlines
Deal found 1/28$232

Find flight deals from Santa Ana to Missouri

Keep the following information in mind while searching for Santa Ana to Missouri flight deals. Data was last updated January 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$167
(CheapOair)

One-way from

$48
(CheapOair)

Popular in

March

Cheapest in

October

Average price

$400
Provider with most accurate pricing for Los Angeles-Lambert-St Louis flight deals.
Search Deals
Provider most trusted by Cheapflights users for Los Angeles-Lambert-St Louis flights.
Search Deals
From Santa Ana J. Wayne/Orange Cnty to Missouri
Search Deals
One-way flight from Santa Ana J. Wayne/Orange Cnty to Missouri
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Santa Ana to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Santa Ana to Missouri that are best for you.

Fly from

Santa Ana

Fly to

Missouri

Route

Depart

Return

Price

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Thu 4/2

4:37 pm-11:31 pm

1 stop4h 54m

Kansas City

Tue 4/7

7:00 am-12:22 pm

1 stop7h 22m

$212

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Thu 4/30

1:20 pm-11:33 pm

1 stop8h 13m

Kansas City

Sat 5/2

7:00 am-12:25 pm

1 stop7h 25m

$217

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Wed 4/1

1:20 pm-11:31 pm

1 stop8h 11m

Kansas City

Mon 4/13

7:00 am-12:22 pm

1 stop7h 22m

$229

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Fri 4/10

4:37 pm-11:31 pm

1 stop4h 54m

Kansas City

Mon 4/13

7:00 am-12:22 pm

1 stop7h 22m

$255

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Wed 4/29

7:00 am-4:17 pm

1 stop7h 17m

Kansas City

Wed 5/6

5:11 pm-10:30 pm

1 stop7h 19m

$257

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Tue 4/28

7:00 am-4:17 pm

1 stop7h 17m

Kansas City

Wed 5/6

5:11 pm-10:30 pm

1 stop7h 19m

$257

Santa AnaSt. Louis

SNA - STL

SNASTL

Santa Ana J. Wayne/Orange Cnty

Tue 3/24

5:00 pm-12:21 am

1 stop5h 21m

Lambert-St Louis

Wed 3/25

6:00 am-11:24 am

1 stop7h 24m

$277

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Sat 2/14

7:25 pm-12:59 pm

2 stops15h 34m

Kansas City

Mon 2/23

7:00 am-12:25 pm

1 stop7h 25m

$279

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Mon 4/6

1:20 pm-11:31 pm

1 stop8h 11m

Kansas City

Fri 4/17

7:00 am-3:42 pm

1 stop10h 42m

$279

Santa AnaKansas City

SNA - MCI

SNAMCI

Santa Ana J. Wayne/Orange Cnty

Thu 4/30

1:20 pm-11:33 pm

1 stop8h 13m

Kansas City

Sat 5/2

2:51 pm-8:50 am

2 stops19h 59m

$282

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/27

Showing 1-10 of 54 results
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Best time to book a flight from Santa Ana to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Santa Ana with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Santa Ana to Missouri

What is the cheapest month to book a flight from Santa Ana, California to Missouri?

Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Missouri (average of $60). Flying from Santa Ana, California to Missouri in January is currently the most expensive (average of $156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated January 29, 2026.
See what other customers who have flown with Southwest, Delta, and United Airlines from Santa Ana to Missouri have to say. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Southwest
8.0
Very good
4,267 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Delta
7.9
Good
8,128 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
United Airlines
7.4
Good
9,215 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
American Airlines
7.2
Good
11,205 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.
Frontier
5.7
Fair
3,056 reviews
Southwest
8.0
Very good
4,267 reviews

Comfort

8.0

Crew

8.6

Boarding

8.1

Overall

8.0

Entertainment

7.5

Food

7.0

Reviews

1 / 20
10.0
Excellent

William Drew,Nov 2025

SJC - HNL

Flight crew was amazing! Usually they're very good on Southwest, but this crew went above and beyond. I have never ever seen so many rounds of drink service on a flight before.

Related info for your journey

Find useful and relevant information for your journey from Santa Ana to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Santa Ana to Missouri?

    For a flight from Santa Ana to Missouri, you will be flying from J. Wayne/Orange Cnty. Santa Ana J. Wayne/Orange Cnty (SNA) is just 4.8 mi from the center of the city.

  • How long is the flight from Santa Ana, California to Missouri?

    For as low as $212, Spirit Airlines can have you in Missouri from Santa Ana, California in 4h 54m. The distance between Santa Ana, California and Missouri is about 1338 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the most popular routes from Santa Ana, California to Missouri?

    When deciding which route to take from Santa Ana, California to Missouri consider Santa Ana J. Wayne/Orange Cnty - Kansas City, Santa Ana J. Wayne/Orange Cnty - Lambert-St Louis or Santa Ana J. Wayne/Orange Cnty - Springfield-Branson as they are the most popular.

  • Can I find deals for flights from Santa Ana to Missouri that include hotel bookings?

    Yes. In addition to deals on Santa Ana to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Santa Ana to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Santa Ana to Missouri.

  • Can I find deals for business class flights from Santa Ana to Missouri?

    Yes. Cheapflights offers flight deals from Santa Ana to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Santa Ana, California to Missouri?

    Currently, June is the cheapest month in which you can book a flight from Santa Ana, California to Missouri (average of $60). Flying from Santa Ana, California to Missouri in January is currently the most expensive (average of $156). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Santa Ana to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Santa Ana to Missouri

Discover the top 6 airlines that operate flights from Santa Ana to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$113Average$214FlexibilityNo cancel feeOn-time62%
DeltaCheapest$128Average$357FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$141Average$326FlexibilityNo cancel feeOn-time65%
SouthwestCheapest$206Average$411FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$263Average$438FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$293Average$480FlexibilityNo cancel feeOn-time69%

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