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Missouri

$68+ Cheap flights from Maine to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/10. Fares are subject to change and may not be available on all flights or dates of travel.
PWM — STL
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Maine to Missouri

Keep the following information in mind while searching for Maine to Missouri flight deals. Data was last updated October 30, 2025.

Most accurate provider

Gotogate
3 stars

Most trusted provider

Gotogate
3 stars

Round-trip from

$269
(American Airlines)

One-way from

$68
(Trip.com)

Popular in

December

Cheapest in

February

Average price

$364
Provider with most accurate pricing for Portland-Lambert-St Louis flight deals.
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Provider most trusted by Cheapflights users for Portland-Lambert-St Louis flights.
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From Maine to Missouri
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One-way flight from Maine to Missouri
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Highest demand for flights based on searches. 12% potential increase in price ($55 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Maine to Missouri

Cheapest flights from Maine to Missouri
Explore the most affordable flight options available from Maine to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This United Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/108:05 amBOS - COU
2 stops10h 35mUnited Airlines
Sat 12/133:25 pmCOU - BOS
1 stop5h 20mUnited Airlines
Deal found 10/28$254
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/96:02 amBGR - MCI
1 stop7h 53mAmerican Airlines
Tue 12/163:33 pmMCI - BGR
1 stop7h 22mAmerican Airlines
Deal found 10/30$269
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/912:45 pmBGR - MCI
2 stops11h 22mUnited Airlines
Tue 12/1612:45 pmMCI - BGR
2 stops9h 02mUnited Airlines
Deal found 10/30$279
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/2411:09 amBOS - COU
1 stop11h 46mAmerican Airlines
Fri 11/286:32 amCOU - BOS
1 stop10h 52mAmerican Airlines
Deal found 10/28$285
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/68:49 amBOS - SGF
1 stop5h 43mAmerican Airlines
Sat 12/134:23 pmSGF - BOS
1 stop5h 21mAmerican Airlines
Deal found 10/28$286
This Delta deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/78:00 amBOS - SGF
1 stop8h 23mDelta
Sat 12/134:08 pmSGF - BOS
1 stop8h 19mDelta
Deal found 10/29$294
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1911:16 amPWM - MCI
1 stop25h 47mMultiple Airlines
Thu 12/43:47 pmMCI - PWM
1 stop16h 19mMultiple Airlines
Deal found 10/30$300
This United Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:40 amBOS - COU
1 stop5h 46mUnited Airlines
Mon 11/173:02 pmCOU - BOS
2 stops7h 40mUnited Airlines
Deal found 10/29$304
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:17 pmPWM - MCI
1 stop6h 37mAmerican Airlines
Mon 12/86:00 amMCI - PWM
1 stop4h 37mAmerican Airlines
Deal found 10/29$313
This Delta deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/65:40 amBOS - SGF
1 stop6h 10mDelta
Sat 12/134:08 pmSGF - BOS
2 stops17h 06mDelta
Deal found 10/28$314
This American Airlines deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/117:19 pmBOS - COU
1 stop15h 34mAmerican Airlines
Sat 11/152:05 pmCOU - BOS
1 stop8h 38mAmerican Airlines
Deal found 10/29$325
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/316:36 amBOS - STL
1 stop10h 47mAmerican Airlines
Sat 1/310:01 amSTL - BOS
Nonstop2h 42mAmerican Airlines
Deal found 10/30$329

Cheapflights Fare Finder

 
Customize your flight search to find flights from Maine to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Maine to Missouri that are best for you.

Fly from

Maine

Fly to

Missouri

Route

Depart

Return

Price

BostonColumbia

BOS - COU

BOSCOU

Boston Logan Intl

Wed 12/10

8:05 am-5:40 pm

2 stops10h 35m

Columbia Regional

Sat 12/13

3:25 pm-9:45 pm

1 stop5h 20m

$254

BangorKansas City

BGR - MCI

BGRMCI

Bangor

Tue 12/9

6:02 am-12:55 pm

1 stop7h 53m

Kansas City

Tue 12/16

3:33 pm-11:55 pm

1 stop7h 22m

$269

BangorKansas City

BGR - MCI

BGRMCI

Bangor

Thu 12/11

5:30 pm-10:59 pm

1 stop6h 29m

Kansas City

Sat 12/13

10:45 am-8:03 pm

2 stops8h 18m

$274

BangorKansas City

BGR - MCI

BGRMCI

Bangor

Tue 12/9

12:45 pm-11:07 pm

2 stops11h 22m

Kansas City

Tue 12/16

12:45 pm-10:47 pm

2 stops9h 02m

$279

BostonColumbia

BOS - COU

BOSCOU

Boston Logan Intl

Wed 12/10

6:00 am-10:00 pm

1 stop17h 00m

Columbia Regional

Sat 12/13

1:55 pm-12:13 am

1 stop9h 18m

$285

BostonColumbia

BOS - COU

BOSCOU

Boston Logan Intl

Mon 11/24

11:09 am-9:55 pm

1 stop11h 46m

Columbia Regional

Fri 11/28

6:32 am-6:24 pm

1 stop10h 52m

$285

BostonSpringfield

BOS - SGF

BOSSGF

Boston Logan Intl

Sun 12/7

5:25 am-10:38 am

1 stop6h 13m

Springfield-Branson

Sat 12/13

2:02 pm-8:33 pm

1 stop5h 31m

$294

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-12:25 pm

1 stop7h 25m

Lambert-St Louis

Tue 1/13

5:29 pm-11:22 pm

1 stop4h 53m

$299

PortlandKansas City

PWM - MCI

PWMMCI

Portland

Wed 11/19

11:16 am-12:03 pm

1 stop25h 47m

Kansas City

Thu 12/4

3:47 pm-9:06 am

1 stop16h 19m

$300

PortlandSt. Louis

PWM - STL

PWMSTL

Portland

Thu 1/8

6:00 am-2:30 pm

2 stops9h 30m

Lambert-St Louis

Tue 1/13

8:05 am-2:39 pm

1 stop5h 34m

$304

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/29

Showing 1-10 of 60 results
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Best time to book a flight from Maine to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Maine with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Maine to Missouri

What is the cheapest month to book a flight from Maine to Missouri?

Currently, August is the cheapest month in which you can book a flight from Maine to Missouri (average of $173). Flying from Maine to Missouri in December is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ME to MO?

Find hourly flight availability from Maine to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 30, 2025.

Unlike in the morning, when flights are generally more expensive, you can save up to 26% on flights from Maine to Missouri by exploring options for tickets in the evening.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 30, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Maine to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Southwest
8.0
Very good
4,243 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
Delta
7.9
Good
7,998 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
United Airlines
7.4
Good
8,998 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines
American Airlines
7.2
Good
11,035 reviews
Southwest
8.0
Very good
4,243 reviews

Overall

8.0

Boarding

8.1

Comfort

8.0

Crew

8.6

Food

7.0

Entertainment

7.5

Reviews

1 / 20
2.0
Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

Find useful and relevant information for your journey from Maine to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Maine to Missouri?

    A quick flight from Maine to Missouri can take about 6h 29m. United Airlines provides one of the quickest options available for as low as $274. The distance from Maine to Missouri is about 1374 mi. Both multi-stop and nonstop flights can be found to your destination and back.

  • What are the cheapest airlines to fly from Maine to Missouri one-way?

    To fly one-way, consider booking your trip with Delta, which is currently one of the cheapest options available, starting at $154. Southwest flights start at $154 while deals on American Airlines start at $216 one-way.

  • Can I find deals for flights from Maine to Missouri that include hotel bookings?

    Yes. In addition to deals on Maine to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Maine to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Maine to Missouri.

  • Can I find deals for business class flights from Maine to Missouri?

    Yes. Cheapflights offers flight deals from Maine to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Maine to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Maine to Missouri (average of $173). Flying from Maine to Missouri in December is currently the most expensive (average of $308). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Maine to Missouri

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Maine to Missouri

Discover the top 4 airlines that operate flights from Maine to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$173Average$376FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$237Average$490FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$243Average$454FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$268Average$648FlexibilityNo cancel feeOn-time69%

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