$83+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MCI
Aug 9 — Aug 161
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Wed 8/128:07 pm
STL
- DSM
1 stop4h 13m
American Airlines
Deal found 7/9![American Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Wed 8/121:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 7/8![Frontier logo]()
$201
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- STL
1 stop3h 15m
Southwest
Thu 8/276:15 pm
STL
- DSM
1 stop3h 55m
Southwest
Deal found 7/7![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- MCI
1 stop6h 15m
Southwest
Thu 8/277:25 am
MCI
- DSM
1 stop6h 20m
Southwest
Deal found 7/7![Southwest logo]()
$228
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Wed 9/910:15 am
STL
- DSM
2 stops11h 40m
Southwest
Deal found 7/9![Southwest logo]()
$232
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 am
DSM
- STL
2 stops9h 20m
Southwest
Sat 10/104:40 pm
STL
- DSM
1 stop4h 05m
Southwest
Deal found 7/7![Southwest logo]()
$233
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/273:05 pm
CID
- MCI
1 stop22h 17m
Frontier
Wed 9/302:17 pm
MCI
- CID
1 stop23h 53m
Frontier
Deal found 7/6![Frontier logo]()
$237
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:55 am
OMA
- STL
1 stop4h 16m
United Airlines
Tue 8/115:30 pm
STL
- OMA
1 stop4h 28m
United Airlines
Deal found 7/7![United Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:10 am
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/188:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/8![Southwest logo]()
$247
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:01 pm
CID
- MCI
1 stop21h 59m
Frontier
Wed 7/151:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 7/6![Frontier logo]()
$252
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/118:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/8![Southwest logo]()
$254
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:39 pm
OMA
- STL
1 stop4h 24m
Delta
Wed 8/266:20 am
STL
- OMA
1 stop5h 40m
Delta
Deal found 7/10![Delta logo]()
$255
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Wed 9/910:15 am
STL
- DSM
2 stops11h 40m
Southwest
Deal found 7/9![Southwest logo]()
$232
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:55 am
OMA
- STL
1 stop4h 16m
United Airlines
Tue 8/115:30 pm
STL
- OMA
1 stop4h 28m
United Airlines
Deal found 7/7![United Airlines logo]()
$245
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:39 pm
OMA
- STL
1 stop4h 24m
Delta
Wed 8/266:20 am
STL
- OMA
1 stop5h 40m
Delta
Deal found 7/10![Delta logo]()
$255
This American Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:00 am
CID
- MCI
1 stop3h 40m
American Airlines
Fri 8/147:39 pm
MCI
- CID
1 stop4h 39m
American Airlines
Deal found 7/8![American Airlines logo]()
$279
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Mon 8/38:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 7/5![Frontier logo]()
$281
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Thu 8/2710:10 am
STL
- DSM
2 stops12h 00m
Southwest
Deal found 7/7![Southwest logo]()
$238
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/202:25 pm
DSM
- MCI
2 stops7h 25m
Southwest
Thu 8/2712:15 pm
MCI
- DSM
2 stops9h 55m
Southwest
Deal found 7/7![Southwest logo]()
$245
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:48 pm
CID
- MCI
1 stop5h 47m
American Airlines
Sat 8/157:39 pm
MCI
- CID
1 stop4h 39m
American Airlines
Deal found 7/7![American Airlines logo]()
$279
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/146:02 am
OMA
- SGF
1 stop4h 46m
United Airlines
Mon 8/175:30 am
SGF
- OMA
1 stop7h 14m
United Airlines
Deal found 7/8![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Mon 9/146:00 am
STL
- OMA
1 stop6h 30m
Southwest
Deal found 7/8![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/258:00 pm
OMA
- COU
2 stops37h 16m
Multiple Airlines
Wed 7/2911:44 am
COU
- OMA
1 stop21h 14m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$624
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Sun 8/95:00 am
STL
- DSM
1 stop4h 56m
American Airlines
Deal found 7/7![American Airlines logo]()
$286
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:40 pm
OMA
- SGF
1 stop4h 47m
United Airlines
Thu 8/1311:20 am
SGF
- OMA
1 stop6h 57m
United Airlines
Deal found 7/5![United Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:06 pm
OMA
- SGF
2 stops28h 41m
Allegiant Air
Thu 8/138:04 pm
SGF
- OMA
1 stop13h 24m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$655
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/185:56 pm
DSM
- STL
1 stop5h 30m
Delta
Tue 8/258:48 am
STL
- DSM
1 stop5h 16m
Delta
Deal found 7/5![Delta logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
DSM
- STL
1 stop6h 11m
United Airlines
Thu 8/610:20 am
STL
- DSM
1 stop4h 07m
United Airlines
Deal found 7/8![United Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:15 pm
OMA
- MCI
2 stops20h 55m
Frontier
Mon 8/101:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 7/5![Frontier logo]()
$373
This Delta deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:55 am
DSM
- STL
1 stop3h 28m
Delta
Wed 8/266:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 7/4![Delta logo]()
$345
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
DSM
- MCI
1 stop3h 45m
Southwest
Sat 8/157:50 am
MCI
- DSM
1 stop3h 40m
Southwest
Deal found 7/9![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:33 pm
CID
- MCI
1 stop3h 50m
American Airlines
Wed 9/307:35 pm
MCI
- CID
1 stop4h 42m
American Airlines
Deal found 7/6![American Airlines logo]()
$328
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:09 am
OMA
- SGF
1 stop6h 43m
United Airlines
Thu 8/131:37 pm
SGF
- OMA
1 stop4h 40m
United Airlines
Deal found 7/8![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/65:40 am
DSM
- STL
1 stop4h 50m
Southwest
Wed 8/123:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 7/9![Southwest logo]()
$289
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:00 am
OMA
- STL
1 stop3h 57m
United Airlines
Wed 9/238:00 am
STL
- OMA
1 stop6h 04m
United Airlines
Deal found 7/7![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:30 am
OMA
- MCI
1 stop3h 45m
Southwest
Sat 8/155:35 am
MCI
- OMA
1 stop6h 10m
Southwest
Deal found 7/9![Southwest logo]()
$291
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:20 pm
OMA
- STL
1 stop3h 45m
Southwest
Tue 8/1112:45 pm
STL
- OMA
2 stops8h 05m
Southwest
Deal found 7/7![Southwest logo]()
$294
This United Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:19 am
OMA
- STL
1 stop4h 19m
United Airlines
Sat 8/155:30 pm
STL
- OMA
1 stop4h 28m
United Airlines
Deal found 7/9![United Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:15 pm
OMA
- MCI
2 stops20h 55m
Frontier
Sat 7/251:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 7/6![Frontier logo]()
$515
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:35 pm
OMA
- COU
1 stop4h 20m
United Airlines
Tue 9/19:00 am
COU
- OMA
1 stop7h 28m
United Airlines
Deal found 7/7![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:57 pm
LSE
- STL
1 stop6h 19m
American Airlines
Mon 8/108:07 pm
STL
- LSE
1 stop4h 15m
American Airlines
Deal found 7/5![American Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/143:50 pm
DSM
- MCI
1 stop6h 15m
Southwest
Sun 8/164:20 pm
MCI
- DSM
1 stop6h 30m
Southwest
Deal found 7/7![Southwest logo]()
$317
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated July 10, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/123:01 pm
CID
- MCI
1 stop21h 59m
Frontier
Wed 7/151:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 7/6![Frontier logo]()
$252
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:55 am
OMA
- STL
1 stop4h 16m
United Airlines
Tue 8/115:30 pm
STL
- OMA
1 stop4h 28m
United Airlines
Deal found 7/7![United Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/118:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/8![Southwest logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Wed 8/121:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 7/8![Frontier logo]()
$201
This American Airlines deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Wed 8/128:07 pm
STL
- DSM
1 stop4h 13m
American Airlines
Deal found 7/9![American Airlines logo]()
$177
This Booking.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Mon 8/108:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 7/5![Frontier logo]()
$264
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/158:10 am
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/188:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/8![Southwest logo]()
$247
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/183:05 pm
OMA
- STL
2 stops7h 05m
Southwest
Tue 8/2512:45 pm
STL
- OMA
2 stops8h 05m
Southwest
Deal found 7/7![Southwest logo]()
$265
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- STL
1 stop3h 15m
Southwest
Thu 8/276:15 pm
STL
- DSM
1 stop3h 55m
Southwest
Deal found 7/7![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/203:50 pm
DSM
- MCI
1 stop6h 15m
Southwest
Thu 8/277:25 am
MCI
- DSM
1 stop6h 20m
Southwest
Deal found 7/7![Southwest logo]()
$228
This Delta deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/225:39 pm
OMA
- STL
1 stop4h 24m
Delta
Wed 8/266:20 am
STL
- OMA
1 stop5h 40m
Delta
Deal found 7/10![Delta logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/239:50 pm
DSM
- MCI
2 stops15h 03m
Multiple Airlines
Sun 8/301:38 pm
MCI
- DSM
1 stop23h 56m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$260
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:19 pm
DSM
- MCI
1 stop22h 41m
Frontier
Deal found 7/9![Frontier logo]()
$83
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:59 pm
DSM
- STL
1 stop5h 17m
Delta
Deal found 7/9![Delta logo]()
$89
This Frontier deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Deal found 7/6![Frontier logo]()
$105
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:15 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 7/7![Southwest logo]()
$113
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/87:00 am
DSM
- STL
1 stop5h 55m
American Airlines
Deal found 7/7![American Airlines logo]()
$114
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/122:40 pm
DSM
- MCI
2 stops7h 10m
Southwest
Deal found 7/9![Southwest logo]()
$120
This United Airlines deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:40 pm
OMA
- STL
1 stop4h 49m
United Airlines
Deal found 7/8![United Airlines logo]()
$123
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:10 am
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 7/9![Southwest logo]()
$124
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 7/6![Frontier logo]()
$125
This Priceline deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 7/9![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/511:32 am
OMA
- STL
2 stops22h 08m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$127
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:10 am
OMA
- STL
1 stop4h 13m
Delta
Deal found 7/8![Delta logo]()
$128
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $177 (American Airlines) |
One-way from | $83 (Kiwi.com) |
Popular in | July |
Cheapest in | May |
Average price | $663 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/8
2:40 pm-5:55 pm
1 stop3h 15m
Lambert-St Louis
Wed 9/9
10:15 am-9:55 pm
2 stops11h 40m
$232
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/20
3:50 pm-10:05 pm
1 stop6h 15m
Lambert-St Louis
Thu 8/27
10:10 am-10:10 pm
2 stops12h 00m
$238
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Fri 8/7
7:55 am-12:11 pm
1 stop4h 16m
Lambert-St Louis
Tue 8/11
5:30 pm-9:58 pm
1 stop4h 28m
$245
Des MoinesKansas City
DSM - MCI
DSMMCI
Des Moines
Thu 8/20
2:25 pm-9:50 pm
2 stops7h 25m
Kansas City
Thu 8/27
12:15 pm-10:10 pm
2 stops9h 55m
$245
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Wed 9/9
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Mon 9/14
6:00 am-12:30 pm
1 stop6h 30m
$251
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Sat 8/22
5:39 pm-10:03 pm
1 stop4h 24m
Lambert-St Louis
Wed 8/26
6:20 am-12:00 pm
1 stop5h 40m
$255
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Fri 8/7
5:00 am-8:40 am
1 stop3h 40m
Kansas City
Fri 8/14
7:39 pm-12:18 am
1 stop4h 39m
$279
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Fri 8/7
6:48 pm-12:35 am
1 stop5h 47m
Kansas City
Sat 8/15
7:39 pm-12:18 am
1 stop4h 39m
$279
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Fri 7/31
8:00 pm-7:23 pm
1 stop23h 23m
Lambert-St Louis
Mon 8/3
8:08 pm-7:15 pm
1 stop23h 07m
$281
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/6
7:49 pm-12:14 am
1 stop4h 25m
Lambert-St Louis
Sun 8/9
5:00 am-9:56 am
1 stop4h 56m
$286
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
OMA-MCI
DSM-MCI
OMA-STL
CID-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
OMA-MCI
DSM-MCI
OMA-STL
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 10, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Food
7.0
Overall
7.9
Boarding
8.1
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on July 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 2 airlines flying from Iowa to Missouri
Discover the top 2 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$356 | FlexibilityNo cancel fee | On-time71% |