$65+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
May 17 — May 241
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 4/13![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Fri 5/229:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/16![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Tue 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Tue 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 4/13![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sun 5/319:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/13![Frontier logo]()
$231
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sun 5/319:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/13![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
OMA
- MCI
1 stop17h 17m
Frontier
Mon 5/42:15 pm
MCI
- OMA
1 stop5h 43m
Frontier
Deal found 4/14![Frontier logo]()
$243
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:25 pm
DSM
- STL
1 stop3h 59m
United Airlines
Mon 5/187:09 pm
STL
- DSM
1 stop5h 30m
United Airlines
Deal found 4/16![United Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/283:22 pm
OMA
- COU
1 stop6h 39m
United Airlines
Sat 5/28:00 am
COU
- OMA
1 stop4h 19m
United Airlines
Deal found 4/13![United Airlines logo]()
$298
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
OMA
- MCI
1 stop17h 17m
Frontier
Mon 5/42:15 pm
MCI
- OMA
1 stop5h 43m
Frontier
Deal found 4/14![Frontier logo]()
$243
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/131:55 pm
OMA
- STL
1 stop7h 20m
Southwest
Sat 5/1610:35 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/16![Southwest logo]()
$273
This Delta deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/71:25 pm
OMA
- STL
1 stop3h 21m
Delta
Mon 5/115:36 pm
STL
- OMA
1 stop5h 20m
Delta
Deal found 4/15![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/283:22 pm
OMA
- COU
1 stop6h 39m
United Airlines
Sat 5/28:00 am
COU
- OMA
1 stop4h 19m
United Airlines
Deal found 4/13![United Airlines logo]()
$298
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:37 pm
LSE
- STL
1 stop3h 40m
American Airlines
Sun 5/35:51 am
STL
- LSE
1 stop3h 44m
American Airlines
Deal found 4/14![American Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/2010:00 am
DSM
- MCI
1 stop24h 22m
Multiple Airlines
Wed 5/2710:35 am
MCI
- DSM
1 stop22h 18m
Multiple Airlines
Deal found 4/16![Multiple Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:35 am
DSM
- STL
1 stop4h 55m
Southwest
Sat 6/64:45 pm
STL
- DSM
1 stop5h 10m
Southwest
Deal found 4/15![Southwest logo]()
$297
This Delta deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:22 pm
CID
- MCI
1 stop6h 39m
Delta
Sun 5/36:00 am
MCI
- CID
1 stop5h 51m
Delta
Deal found 4/14![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/210:05 am
LSE
- STL
2 stops9h 25m
American Airlines
Tue 5/58:03 pm
STL
- LSE
1 stop3h 51m
American Airlines
Deal found 4/12![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/11:00 pm
OMA
- SGF
1 stop4h 44m
United Airlines
Tue 5/58:00 am
SGF
- OMA
1 stop4h 19m
United Airlines
Deal found 4/16![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:20 am
DSM
- STL
2 stops9h 30m
Southwest
Mon 6/155:35 am
STL
- DSM
1 stop7h 15m
Southwest
Deal found 4/16![Southwest logo]()
$303
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/116:39 pm
DSM
- STL
1 stop5h 17m
Delta
Fri 6/125:24 pm
STL
- DSM
1 stop5h 07m
Delta
Deal found 4/13![Delta logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:17 am
OMA
- SGF
1 stop5h 07m
American Airlines
Tue 5/56:05 pm
SGF
- OMA
1 stop5h 54m
American Airlines
Deal found 4/16![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:00 am
OMA
- STL
1 stop6h 11m
United Airlines
Wed 6/35:41 pm
STL
- OMA
1 stop5h 39m
United Airlines
Deal found 4/12![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/273:35 pm
DSM
- STL
1 stop6h 10m
Southwest
Tue 6/3010:15 am
STL
- DSM
2 stops12h 30m
Southwest
Deal found 4/12![Southwest logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:29 pm
OMA
- MCI
1 stop16h 31m
Multiple Airlines
Fri 7/107:37 pm
MCI
- OMA
1 stop21h 04m
Multiple Airlines
Deal found 4/12![Multiple Airlines logo]()
$377
This Delta deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:34 am
OMA
- STL
1 stop3h 58m
Delta
Mon 5/258:53 am
STL
- OMA
1 stop3h 32m
Delta
Deal found 4/12![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:00 am
OMA
- STL
1 stop6h 11m
United Airlines
Wed 5/274:48 pm
STL
- OMA
1 stop6h 54m
United Airlines
Deal found 4/15![United Airlines logo]()
$337
This Southwest deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/145:25 am
DSM
- STL
1 stop3h 40m
Southwest
Thu 5/217:20 am
STL
- DSM
1 stop4h 25m
Southwest
Deal found 4/16![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:17 am
OMA
- SGF
1 stop5h 07m
American Airlines
Fri 5/86:09 pm
SGF
- OMA
1 stop5h 50m
American Airlines
Deal found 4/12![American Airlines logo]()
$349
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/226:34 am
OMA
- STL
1 stop3h 58m
Delta
Tue 5/265:36 pm
STL
- OMA
1 stop5h 20m
Delta
Deal found 4/13![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/85:25 am
DSM
- STL
1 stop3h 40m
Southwest
Sat 5/95:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 4/12![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/165:35 pm
LSE
- STL
1 stop6h 21m
American Airlines
Sun 7/197:00 am
STL
- LSE
1 stop4h 15m
American Airlines
Deal found 4/12![American Airlines logo]()
$353
This United Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/251:49 pm
OMA
- COU
1 stop6h 41m
United Airlines
Sat 8/298:00 am
COU
- OMA
1 stop4h 18m
United Airlines
Deal found 4/14![United Airlines logo]()
$358
This Delta deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/286:34 am
OMA
- STL
1 stop3h 58m
Delta
Sun 5/316:21 am
STL
- OMA
1 stop3h 54m
Delta
Deal found 4/13![Delta logo]()
$335
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/124:15 pm
DSM
- STL
1 stop6h 35m
Southwest
Fri 7/176:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 4/13![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 am
LSE
- MCI
2 stops11h 22m
American Airlines
Tue 7/214:34 pm
MCI
- LSE
1 stop7h 25m
American Airlines
Deal found 4/16![American Airlines logo]()
$359
This United Airlines deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:15 am
CID
- MCI
1 stop7h 00m
United Airlines
Wed 5/138:49 am
MCI
- CID
1 stop5h 15m
United Airlines
Deal found 4/12![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:25 am
DSM
- STL
1 stop4h 50m
Southwest
Fri 6/56:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 4/13![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/275:35 pm
LSE
- STL
1 stop6h 21m
American Airlines
Mon 8/106:06 am
STL
- LSE
1 stop4h 17m
American Airlines
Deal found 4/14![American Airlines logo]()
$364
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated April 17, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated April 17, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/283:22 pm
OMA
- COU
1 stop6h 39m
United Airlines
Sat 5/28:00 am
COU
- OMA
1 stop4h 19m
United Airlines
Deal found 4/13![United Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
OMA
- MCI
1 stop17h 17m
Frontier
Mon 5/42:15 pm
MCI
- OMA
1 stop5h 43m
Frontier
Deal found 4/14![Frontier logo]()
$243
This United Airlines deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:25 pm
DSM
- STL
1 stop3h 59m
United Airlines
Mon 5/187:09 pm
STL
- DSM
1 stop5h 30m
United Airlines
Deal found 4/16![United Airlines logo]()
$297
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Fri 5/229:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/16![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Tue 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 4/13![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sun 5/319:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/13![Frontier logo]()
$232
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 4/13![Frontier logo]()
$190
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Tue 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Wed 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/13![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Sun 5/319:06 pm
STL
- OMA
2 stops22h 28m
Frontier
Deal found 4/13![Frontier logo]()
$231
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated April 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/168:25 pm
OMA
- STL
1 stop22h 58m
Frontier
Deal found 4/14![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/16![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/15![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/108:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/14![Frontier logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 4/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/16![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/98:25 pm
OMA
- STL
2 stops21h 53m
Frontier
Deal found 4/13![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/12![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:19 pm
OMA
- STL
2 stops21h 14m
Frontier
Deal found 4/12![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 4/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:19 pm
OMA
- MCI
1 stop17h 30m
Frontier
Deal found 4/14![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:19 pm
OMA
- MCI
1 stop17h 30m
Frontier
Deal found 4/13![Frontier logo]()
$124
This American Airlines deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:00 am
DSM
- STL
1 stop6h 27m
American Airlines
Deal found 4/15![American Airlines logo]()
$163
This Southwest deal was found by Cheapflights users on 4/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/105:20 am
DSM
- STL
2 stops9h 15m
Southwest
Deal found 4/15![Southwest logo]()
$168
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated April 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Kiwi.com) |
One-way from | $65 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $328 |
Good round-trip deal | $105 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaKansas City
OMA - MCI
OMAMCI
Omaha Eppley Airfield
Fri 5/1
8:49 pm-2:06 pm
1 stop17h 17m
Kansas City
Mon 5/4
2:15 pm-7:58 pm
1 stop5h 43m
$243
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Wed 5/13
1:55 pm-9:15 pm
1 stop7h 20m
Lambert-St Louis
Sat 5/16
10:35 am-11:55 am
Nonstop1h 20m
$273
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Thu 5/7
1:25 pm-4:46 pm
1 stop3h 21m
Lambert-St Louis
Mon 5/11
5:36 pm-10:56 pm
1 stop5h 20m
$279
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 5/30
5:35 am-10:30 am
1 stop4h 55m
Lambert-St Louis
Sat 6/6
4:45 pm-9:55 pm
1 stop5h 10m
$297
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Tue 4/28
3:22 pm-10:01 pm
1 stop6h 39m
Columbia Regional
Sat 5/2
8:00 am-12:19 pm
1 stop4h 19m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 6/10
5:20 am-2:50 pm
2 stops9h 30m
Lambert-St Louis
Mon 6/15
5:35 am-12:50 pm
1 stop7h 15m
$303
Quickest round-trip
La CrosseSt. Louis
LSE - STL
LSESTL
La Crosse
Wed 4/29
6:37 pm-10:17 pm
1 stop3h 40m
Lambert-St Louis
Sun 5/3
5:51 am-9:35 am
1 stop3h 44m
$308
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Sat 5/2
4:22 pm-11:01 pm
1 stop6h 39m
Kansas City
Sun 5/3
6:00 am-11:51 am
1 stop5h 51m
$309
La CrosseSt. Louis
LSE - STL
LSESTL
La Crosse
Sat 5/2
10:05 am-7:30 pm
2 stops9h 25m
Lambert-St Louis
Tue 5/5
8:03 pm-11:54 pm
1 stop3h 51m
$309
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 6/27
3:35 pm-9:45 pm
1 stop6h 10m
Lambert-St Louis
Tue 6/30
10:15 am-10:45 pm
2 stops12h 30m
$309
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
OMA-STL
OMA-MCI
DSM-STL
OMA-COU
LSE-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
OMA-STL
OMA-MCI
DSM-STL
OMA-COU
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $77). Flying from Iowa to Missouri in February is currently the most expensive (average of $274). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated April 17, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Food
7.0
Boarding
8.1
Entertainment
7.5
Overall
8.0
Comfort
8.0
Crew
8.6
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on April 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$253 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$418 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$302 | FlexibilityNo cancel fee | On-time71% |