$96+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Sep 12 — Sep 191
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop8h 08m
Sun 9/138:32 pm -
1 stop23h 01m
Deal found 8/11![Frontier logo]()
$202
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 50m
Fri 9/113:15 pm -
2 stops7h 00m
Deal found 8/12![Southwest logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:29 pm -
1 stop23h 48m
Fri 9/188:10 pm -
1 stop22h 24m
Deal found 8/11![Frontier logo]()
$223
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:20 am -
Nonstop1h 15m
Fri 9/118:30 am -
Nonstop1h 15m
Deal found 8/10![Southwest logo]()
$225
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:24 am -
1 stop5h 33m
Fri 9/118:00 am -
1 stop4h 16m
Deal found 8/12![United Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:29 pm -
1 stop24h 08m
Fri 9/188:32 pm -
1 stop22h 02m
Deal found 8/11![Frontier logo]()
$229
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:40 pm -
1 stop4h 35m
Tue 9/153:35 pm -
1 stop6h 25m
Deal found 8/9![Southwest logo]()
$234
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
1 stop6h 11m
Sat 10/311:01 am -
1 stop6h 26m
Deal found 8/12![American Airlines logo]()
$234
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:24 am -
1 stop3h 48m
Sat 9/1212:59 pm -
1 stop4h 29m
Deal found 8/11![United Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
2 stops12h 45m
Sat 9/128:25 am -
1 stop3h 05m
Deal found 8/12![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
2 stops10h 05m
Sat 10/317:40 am -
2 stops10h 05m
Deal found 8/10![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:20 pm -
1 stop5h 57m
Wed 9/28:30 am -
1 stop3h 50m
Deal found 8/11![United Airlines logo]()
$245
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 13, 2026.
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:00 am -
1 stop6h 30m
Sat 10/3111:10 am -
1 stop6h 35m
Deal found 8/10![Southwest logo]()
$234
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2610:57 am -
1 stop4h 15m
Sat 10/36:15 am -
1 stop4h 02m
Deal found 8/12![Delta logo]()
$235
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/33:15 pm -
1 stop6h 23m
Sat 11/73:00 pm -
1 stop4h 38m
Deal found 8/12![United Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/98:41 pm -
1 stop16h 41m
Mon 10/122:17 pm -
1 stop5h 29m
Deal found 8/11![Frontier logo]()
$340
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:19 pm -
2 stops29h 18m
Sat 9/268:32 pm -
1 stop17h 38m
Deal found 8/10![Multiple Airlines logo]()
$355
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:00 am -
1 stop6h 48m
Thu 9/177:35 pm -
1 stop4h 42m
Deal found 8/11![American Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:40 pm -
1 stop4h 35m
Tue 9/153:35 pm -
1 stop6h 25m
Deal found 8/9![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/315:40 am -
2 stops12h 45m
Wed 9/22:50 pm -
2 stops6h 10m
Deal found 8/11![Southwest logo]()
$256
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:00 am -
1 stop4h 12m
Sun 11/2210:53 am -
1 stop6h 30m
Deal found 8/12![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/911:25 am -
1 stop8h 35m
Thu 9/105:15 am -
1 stop5h 10m
Deal found 8/10![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2411:36 am -
1 stop4h 07m
Sun 9/278:00 am -
1 stop6h 15m
Deal found 8/12![United Airlines logo]()
$297
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:50 pm -
1 stop6h 20m
Fri 9/256:15 pm -
1 stop4h 00m
Deal found 8/9![Southwest logo]()
$266
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/256:02 am -
1 stop4h 14m
Sat 8/293:12 pm -
1 stop4h 25m
Deal found 8/10![United Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:22 pm -
1 stop16h 56m
Wed 9/165:00 am -
1 stop19h 20m
Deal found 8/11![American Airlines logo]()
$395
This United Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:00 pm -
1 stop4h 42m
Sun 9/205:30 am -
1 stop5h 13m
Deal found 8/9![United Airlines logo]()
$310
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/254:50 pm -
Nonstop1h 15m
Sun 9/278:45 pm -
Nonstop1h 20m
Deal found 8/9![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:55 pm -
1 stop4h 04m
Thu 10/18:00 am -
1 stop6h 15m
Deal found 8/11![United Airlines logo]()
$315
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/275:40 am -
1 stop4h 00m
Wed 9/308:25 am -
1 stop3h 25m
Deal found 8/12![Southwest logo]()
$296
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:33 pm -
1 stop3h 50m
Thu 9/247:35 pm -
1 stop4h 42m
Deal found 8/9![American Airlines logo]()
$437
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop3h 50m
Mon 9/215:15 am -
1 stop5h 10m
Deal found 8/11![Southwest logo]()
$296
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:00 am -
1 stop6h 30m
Sun 12/131:08 pm -
1 stop6h 17m
Deal found 8/12![United Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:01 am -
1 stop4h 51m
Sat 11/1411:29 am -
1 stop6h 47m
Deal found 8/8![American Airlines logo]()
$470
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2511:19 am -
1 stop6h 43m
Sat 8/295:05 pm -
1 stop6h 37m
Deal found 8/10![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:50 pm -
2 stops7h 30m
Sun 9/134:20 pm -
1 stop6h 35m
Deal found 8/11![Southwest logo]()
$301
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/281:55 pm -
1 stop6h 52m
Tue 9/15:30 am -
1 stop7h 14m
Deal found 8/13![United Airlines logo]()
$329
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
2 stops9h 40m
Wed 9/162:45 pm -
2 stops7h 15m
Deal found 8/10![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/95:22 pm -
1 stop7h 01m
Sat 9/125:13 am -
1 stop6h 09m
Deal found 8/10![American Airlines logo]()
$508
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:13 pm -
1 stop6h 08m
Thu 10/88:00 am -
1 stop4h 14m
Deal found 8/12![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:05 am -
1 stop9h 00m
Fri 9/42:55 pm -
Nonstop1h 15m
Deal found 8/10![Southwest logo]()
$309
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/166:55 pm -
1 stop13h 47m
Mon 10/197:34 pm -
1 stop16h 19m
Deal found 8/10![American Airlines logo]()
$508
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated August 13, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated August 13, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/313:20 pm -
1 stop5h 57m
Wed 9/28:30 am -
1 stop3h 50m
Deal found 8/11![United Airlines logo]()
$245
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:40 pm -
1 stop4h 35m
Tue 9/153:35 pm -
1 stop6h 25m
Deal found 8/9![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:20 am -
Nonstop1h 15m
Fri 9/118:30 am -
Nonstop1h 15m
Deal found 8/10![Southwest logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:29 am -
1 stop8h 08m
Sun 9/138:32 pm -
1 stop23h 01m
Deal found 8/11![Frontier logo]()
$202
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
1 stop4h 50m
Fri 9/113:15 pm -
2 stops7h 00m
Deal found 8/12![Southwest logo]()
$215
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:24 am -
1 stop5h 33m
Fri 9/118:00 am -
1 stop4h 16m
Deal found 8/12![United Airlines logo]()
$227
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/106:24 am -
1 stop3h 48m
Sat 9/1212:59 pm -
1 stop4h 29m
Deal found 8/11![United Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/105:40 am -
2 stops12h 45m
Sat 9/128:25 am -
1 stop3h 05m
Deal found 8/12![Southwest logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:29 pm -
1 stop23h 48m
Fri 9/188:10 pm -
1 stop22h 24m
Deal found 8/11![Frontier logo]()
$223
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:50 pm -
Nonstop1h 15m
Mon 9/148:45 pm -
Nonstop1h 20m
Deal found 8/12![Southwest logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:29 pm -
1 stop24h 08m
Fri 9/188:32 pm -
1 stop22h 02m
Deal found 8/11![Frontier logo]()
$229
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/267:05 am -
1 stop6h 11m
Sat 10/311:01 am -
1 stop6h 26m
Deal found 8/12![American Airlines logo]()
$234
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 13, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:29 pm -
1 stop23h 48m
Deal found 8/13![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/117:29 pm -
1 stop23h 48m
Deal found 8/11![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/97:29 pm -
1 stop24h 08m
Deal found 8/10![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:41 pm -
1 stop22h 34m
Deal found 8/11![Frontier logo]()
$109
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am -
1 stop4h 12m
Deal found 8/8![United Airlines logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:29 pm -
1 stop16h 38m
Deal found 8/11![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:41 pm -
1 stop22h 34m
Deal found 8/11![Frontier logo]()
$115
This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:10 am -
1 stop3h 50m
Deal found 8/11![Southwest logo]()
$118
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/98:20 am -
Nonstop1h 15m
Deal found 8/9![Southwest logo]()
$118
This Southwest deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/114:50 pm -
Nonstop1h 15m
Deal found 8/12![Southwest logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/107:29 pm -
1 stop24h 08m
Deal found 8/11![Frontier logo]()
$120
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:21 pm -
1 stop5h 55m
Deal found 8/13![United Airlines logo]()
$123
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated August 13, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $202 (Kiwi.com) |
One-way from | $96 (Kiwi.com) |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesKansas City
DSM Des Moines - MCI Kansas City
DSMMCI
Des Moines
Sat 10/24
7:00 am-1:30 pm
1 stop6h 30m
Kansas City
Sat 10/31
11:10 am-5:45 pm
1 stop6h 35m
$234
Des MoinesKansas City
DSM Des Moines - MCI Kansas City
DSMMCI
Des Moines
Tue 9/8
6:40 pm-11:15 pm
1 stop4h 35m
Kansas City
Tue 9/15
3:35 pm-10:00 pm
1 stop6h 25m
$234
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sat 9/26
10:57 am-3:12 pm
1 stop4h 15m
Lambert-St Louis
Sat 10/3
6:15 am-10:17 am
1 stop4h 02m
$235
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 8/31
5:40 am-6:25 pm
2 stops12h 45m
Lambert-St Louis
Wed 9/2
2:50 pm-9:00 pm
2 stops6h 10m
$256
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Wed 9/9
11:25 am-8:00 pm
1 stop8h 35m
Lambert-St Louis
Thu 9/10
5:15 am-10:25 am
1 stop5h 10m
$261
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 9/21
3:50 pm-10:10 pm
1 stop6h 20m
Lambert-St Louis
Fri 9/25
6:15 pm-10:15 pm
1 stop4h 00m
$266
OmahaColumbia
OMA Omaha Eppley Airfield - COU Columbia Regional
OMACOU
Omaha Eppley Airfield
Tue 11/3
3:15 pm-9:38 pm
1 stop6h 23m
Columbia Regional
Sat 11/7
3:00 pm-7:38 pm
1 stop4h 38m
$278
Quickest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Fri 9/25
4:50 pm-6:05 pm
Nonstop1h 15m
Lambert-St Louis
Sun 9/27
8:45 pm-10:05 pm
Nonstop1h 20m
$292
Des MoinesKansas City
DSM Des Moines - MCI Kansas City
DSMMCI
Des Moines
Sun 9/27
5:40 am-9:40 am
1 stop4h 00m
Kansas City
Wed 9/30
8:25 am-11:50 am
1 stop3h 25m
$296
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Fri 9/18
6:20 pm-10:10 pm
1 stop3h 50m
Lambert-St Louis
Mon 9/21
5:15 am-10:25 am
1 stop5h 10m
$296
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-MCI
DSM-STL
OMA-STL
OMA-MCI
OMA-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-MCI
DSM-STL
OMA-STL
OMA-MCI
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 13, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Boarding
8.1
Overall
8.0
Entertainment
7.5
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on August 13, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 2 airlines flying from Iowa to Missouri
Discover the top 2 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 13, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$452 | FlexibilityNo cancel fee | On-time71% |