$110+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MCI
Jul 10 — Jul 171
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 10, 2026.
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/85:35 pm
DSM
- STL
1 stop5h 26m
Delta
Tue 9/1511:16 am
STL
- DSM
1 stop5h 25m
Delta
Deal found 6/9![Delta logo]()
$227
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Tue 9/153:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 6/9![Southwest logo]()
$232
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Wed 7/158:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/8![Frontier logo]()
$242
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 8/58:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/8![Southwest logo]()
$247
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/148:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/6![Frontier logo]()
$249
This Delta deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/46:10 am
OMA
- STL
1 stop4h 13m
Delta
Wed 8/56:20 am
STL
- OMA
1 stop4h 09m
Delta
Deal found 6/8![Delta logo]()
$255
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:05 am
DSM
- MCI
1 stop9h 30m
Southwest
Tue 11/179:55 am
MCI
- DSM
1 stop4h 15m
Southwest
Deal found 6/7![Southwest logo]()
$256
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:01 pm
CID
- MCI
1 stop21h 59m
Frontier
Mon 7/131:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 6/10![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Tue 7/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/6![Frontier logo]()
$262
This Booking.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/78:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/5![Frontier logo]()
$262
This Booking.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/201:55 pm
CID
- MCI
1 stop23h 05m
Frontier
Sat 8/221:45 pm
MCI
- CID
1 stop5h 46m
Frontier
Deal found 6/7![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Wed 7/151:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/10![Frontier logo]()
$270
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 10, 2026.
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/82:40 pm
DSM
- STL
1 stop3h 15m
Southwest
Tue 9/153:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 6/9![Southwest logo]()
$232
This Booking.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Tue 7/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/6![Frontier logo]()
$262
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:33 pm
CID
- MCI
1 stop4h 44m
United Airlines
Sun 7/56:41 pm
MCI
- CID
1 stop4h 01m
United Airlines
Deal found 6/6![United Airlines logo]()
$284
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:20 am
OMA
- SGF
1 stop4h 52m
American Airlines
Sat 7/117:53 pm
SGF
- OMA
1 stop4h 13m
American Airlines
Deal found 6/5![American Airlines logo]()
$289
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- MCI
1 stop17h 00m
Multiple Airlines
Wed 7/156:07 pm
MCI
- OMA
2 stops39h 28m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$293
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 8/58:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/8![Southwest logo]()
$247
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:00 am
CID
- MCI
1 stop3h 40m
American Airlines
Sat 8/225:00 am
MCI
- CID
1 stop5h 45m
American Airlines
Deal found 6/8![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3112:34 pm
CID
- MCI
1 stop6h 08m
United Airlines
Sun 11/17:55 pm
MCI
- CID
1 stop4h 30m
United Airlines
Deal found 6/9![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:16 pm
CID
- MCI
1 stop5h 13m
American Airlines
Mon 12/77:41 pm
MCI
- CID
1 stop3h 36m
American Airlines
Deal found 6/7![American Airlines logo]()
$289
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
OMA
- SGF
1 stop4h 46m
United Airlines
Sat 7/116:34 pm
SGF
- OMA
1 stop4h 40m
United Airlines
Deal found 6/9![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:15 pm
OMA
- STL
1 stop4h 55m
Southwest
Tue 8/258:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/9![Southwest logo]()
$302
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/45:20 am
OMA
- SGF
1 stop4h 52m
American Airlines
Sat 7/117:53 pm
SGF
- OMA
1 stop4h 13m
American Airlines
Deal found 6/6![American Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/295:27 pm
OMA
- SGF
1 stop6h 15m
United Airlines
Fri 7/36:34 pm
SGF
- OMA
1 stop4h 40m
United Airlines
Deal found 6/9![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Sun 8/96:00 am
STL
- DSM
1 stop5h 35m
Southwest
Deal found 6/9![Southwest logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:15 pm
OMA
- MCI
1 stop16h 45m
Multiple Airlines
Fri 7/107:37 pm
MCI
- OMA
1 stop21h 04m
Multiple Airlines
Deal found 6/9![Multiple Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:00 am
DSM
- STL
1 stop6h 13m
United Airlines
Sat 10/107:01 pm
STL
- DSM
1 stop4h 34m
United Airlines
Deal found 6/5![United Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/75:20 am
DSM
- STL
1 stop5h 55m
Southwest
Tue 7/1410:15 am
STL
- DSM
2 stops11h 30m
Southwest
Deal found 6/9![Southwest logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:15 pm
OMA
- MCI
1 stop16h 45m
Frontier
Tue 7/141:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/8![Frontier logo]()
$410
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:10 pm
OMA
- SGF
1 stop4h 34m
American Airlines
Wed 7/17:53 pm
SGF
- OMA
1 stop4h 06m
American Airlines
Deal found 6/9![American Airlines logo]()
$314
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/75:35 am
DSM
- STL
2 stops10h 00m
Southwest
Sat 10/106:35 am
STL
- DSM
1 stop7h 00m
Southwest
Deal found 6/5![Southwest logo]()
$313
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:20 pm
DSM
- STL
1 stop6h 40m
United Airlines
Wed 8/197:25 am
STL
- DSM
1 stop6h 51m
United Airlines
Deal found 6/9![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:20 am
OMA
- SGF
1 stop4h 37m
American Airlines
Mon 8/178:04 pm
SGF
- OMA
1 stop4h 06m
American Airlines
Deal found 6/10![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/274:40 pm
DSM
- STL
2 stops6h 10m
Southwest
Tue 7/288:25 am
STL
- DSM
1 stop6h 40m
Southwest
Deal found 6/5![Southwest logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/46:40 pm
OMA
- COU
1 stop4h 53m
United Airlines
Wed 7/88:00 am
COU
- OMA
1 stop6h 17m
United Airlines
Deal found 6/9![United Airlines logo]()
$338
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/65:10 am
DSM
- STL
2 stops8h 40m
Southwest
Tue 7/75:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Deal found 6/5![Southwest logo]()
$324
This American Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/207:48 pm
OMA
- STL
1 stop4h 28m
American Airlines
Wed 7/221:25 pm
STL
- OMA
1 stop4h 31m
American Airlines
Deal found 6/6![American Airlines logo]()
$371
This United Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/291:55 pm
OMA
- COU
1 stop7h 04m
United Airlines
Tue 9/16:15 am
COU
- OMA
1 stop6h 05m
United Airlines
Deal found 6/5![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:20 am
DSM
- STL
2 stops9h 25m
Southwest
Thu 7/166:30 pm
STL
- DSM
1 stop5h 05m
Southwest
Deal found 6/5![Southwest logo]()
$324
This United Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:33 pm
CID
- MCI
1 stop4h 44m
United Airlines
Mon 7/136:41 pm
MCI
- CID
1 stop4h 01m
United Airlines
Deal found 6/8![United Airlines logo]()
$354
This Southwest deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- STL
2 stops9h 30m
Southwest
Thu 7/304:25 pm
STL
- DSM
2 stops7h 10m
Southwest
Deal found 6/5![Southwest logo]()
$329
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated June 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated June 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:33 pm
CID
- MCI
1 stop4h 44m
United Airlines
Sun 7/56:41 pm
MCI
- CID
1 stop4h 01m
United Airlines
Deal found 6/6![United Airlines logo]()
$284
This Booking.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/58:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Tue 7/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/6![Frontier logo]()
$262
This United Airlines deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/56:00 am
OMA
- COU
1 stop4h 13m
United Airlines
Sat 7/118:00 am
COU
- OMA
1 stop6h 23m
United Airlines
Deal found 6/6![United Airlines logo]()
$278
This American Airlines deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/55:20 am
OMA
- SGF
1 stop4h 52m
American Airlines
Sat 7/117:53 pm
SGF
- OMA
1 stop4h 13m
American Airlines
Deal found 6/5![American Airlines logo]()
$289
This Frontier deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/148:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/6![Frontier logo]()
$249
This Booking.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/62:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Tue 7/78:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/5![Frontier logo]()
$262
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/73:01 pm
CID
- MCI
1 stop21h 59m
Frontier
Mon 7/131:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 6/10![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Wed 7/158:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/8![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Wed 7/151:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/10![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/88:00 pm
OMA
- MCI
1 stop17h 00m
Multiple Airlines
Wed 7/156:07 pm
MCI
- OMA
2 stops39h 28m
Multiple Airlines
Deal found 6/10![Multiple Airlines logo]()
$293
This Booking.com deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/98:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Tue 7/148:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/10![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/238:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Sat 7/258:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/9![Frontier logo]()
$275
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated June 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:29 pm
OMA
- STL
1 stop22h 54m
Frontier
Deal found 6/6![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 6/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:19 pm
OMA
- MCI
1 stop16h 41m
Frontier
Deal found 6/5![Frontier logo]()
$114
This American Airlines deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/117:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Deal found 6/8![American Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 6/6![Frontier logo]()
$115
This Southwest deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:10 am
DSM
- STL
2 stops10h 15m
Southwest
Deal found 6/8![Southwest logo]()
$119
This Southwest deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/44:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/7![Southwest logo]()
$124
This Booking.com deal was found by Cheapflights users on 6/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/8![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 6/6![Frontier logo]()
$127
This Delta deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:39 pm
OMA
- STL
1 stop5h 47m
Delta
Deal found 6/9![Delta logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/7![Frontier logo]()
$129
This Frontier deal was found by Cheapflights users on 6/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/172:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Deal found 6/7![Frontier logo]()
$135
This American Airlines deal was found by Cheapflights users on 6/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/127:58 pm
DSM
- STL
1 stop4h 29m
American Airlines
Deal found 6/9![American Airlines logo]()
$136
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated June 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Delta) |
One-way from | $110 (Kiwi.com) |
Popular in | July |
Cheapest in | May |
Average price | $334 |
Good round-trip deal | $105 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 9/8
2:40 pm-5:55 pm
1 stop3h 15m
Lambert-St Louis
Tue 9/15
3:05 pm-9:55 pm
2 stops6h 50m
$232
Quickest round-trip
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 8/4
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Wed 8/5
8:30 am-9:45 am
Nonstop1h 15m
$247
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Sun 7/5
8:00 pm-7:23 pm
1 stop23h 23m
Lambert-St Louis
Tue 7/7
8:08 pm-7:15 pm
1 stop23h 07m
$262
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Fri 7/3
6:33 pm-11:17 pm
1 stop4h 44m
Kansas City
Sun 7/5
6:41 pm-10:42 pm
1 stop4h 01m
$284
OmahaSpringfield
OMA - SGF
OMASGF
Omaha Eppley Airfield
Sun 7/5
5:20 am-10:12 am
1 stop4h 52m
Springfield-Branson
Sat 7/11
7:53 pm-12:06 am
1 stop4h 13m
$289
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Thu 8/20
5:00 am-8:40 am
1 stop3h 40m
Kansas City
Sat 8/22
5:00 am-10:45 am
1 stop5h 45m
$289
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Sat 10/31
12:34 pm-6:42 pm
1 stop6h 08m
Kansas City
Sun 11/1
7:55 pm-12:25 am
1 stop4h 30m
$289
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Fri 12/4
4:16 pm-9:29 pm
1 stop5h 13m
Kansas City
Mon 12/7
7:41 pm-11:17 pm
1 stop3h 36m
$289
OmahaKansas City
OMA - MCI
OMAMCI
Omaha Eppley Airfield
Wed 7/8
8:00 pm-1:00 pm
1 stop17h 00m
Kansas City
Wed 7/15
6:07 pm-9:35 am
2 stops39h 28m
$293
OmahaSpringfield
OMA - SGF
OMASGF
Omaha Eppley Airfield
Sun 7/5
6:00 am-10:46 am
1 stop4h 46m
Springfield-Branson
Sat 7/11
6:34 pm-11:14 pm
1 stop4h 40m
$299
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
OMA-STL
CID-MCI
OMA-SGF
OMA-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
OMA-STL
CID-MCI
OMA-SGF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 10, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Entertainment
7.5
Overall
7.9
Crew
8.6
Boarding
8.1
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on June 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$132 | Average$297 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$158 | Average$344 | FlexibilityNo cancel fee | On-time71% |