$130+ Cheap flights from Iowa to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/13. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop8h 20m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/4![Southwest logo]()
$286
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:54 am -
1 stop7h 05m
Mon 12/76:29 pm -
1 stop5h 30m
Deal found 11/2![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:15 pm -
1 stop3h 50m
Tue 12/159:40 am -
1 stop4h 34m
Deal found 11/3![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:30 pm -
1 stop6h 30m
Sun 12/139:35 am -
1 stop9h 00m
Deal found 11/3![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:15 am -
1 stop4h 35m
Wed 12/97:30 am -
1 stop6h 44m
Deal found 11/4![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:28 pm -
1 stop3h 56m
Fri 12/47:20 pm -
1 stop4h 56m
Deal found 11/2![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:05 am -
1 stop6h 17m
Mon 12/75:40 pm -
1 stop4h 08m
Deal found 11/2![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:23 am -
1 stop7h 33m
Wed 12/91:50 pm -
1 stop5h 11m
Deal found 11/4![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:28 pm -
1 stop3h 56m
Sun 12/65:17 am -
1 stop5h 07m
Deal found 11/1![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:11 am -
1 stop6h 04m
Tue 11/248:05 pm -
1 stop4h 14m
Deal found 11/2![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 32m
Fri 11/276:00 am -
1 stop4h 24m
Deal found 11/2![United Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:00 am -
1 stop4h 42m
Tue 12/296:58 pm -
1 stop3h 47m
Deal found 11/2![United Airlines logo]()
$330
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
1 stop4h 13m
Sat 1/96:45 pm -
1 stop4h 29m
Deal found 11/2![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:40 am -
1 stop6h 00m
Sun 12/205:30 am -
1 stop5h 45m
Deal found 11/3![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/18:28 pm -
1 stop3h 56m
Tue 12/86:55 am -
1 stop4h 34m
Deal found 11/2![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:15 am -
1 stop4h 39m
Sun 11/296:13 am -
1 stop4h 07m
Deal found 11/2![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop27h 48m
Thu 11/199:01 am -
1 stop24h 05m
Deal found 10/31![Allegiant Air logo]()
$601
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/134:25 pm -
1 stop6h 25m
Tue 12/1511:55 am -
2 stops10h 10m
Deal found 11/3![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:15 am -
1 stop4h 35m
Wed 12/97:30 am -
1 stop6h 44m
Deal found 11/4![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:11 am -
1 stop6h 04m
Tue 11/248:05 pm -
1 stop4h 14m
Deal found 11/2![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:45 am -
1 stop5h 36m
Sat 11/286:13 am -
1 stop4h 06m
Deal found 11/3![Delta logo]()
$336
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:05 am -
1 stop6h 17m
Mon 12/75:40 pm -
1 stop4h 08m
Deal found 11/1![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:30 pm -
1 stop6h 30m
Sun 12/138:30 am -
2 stops10h 05m
Deal found 11/3![Southwest logo]()
$309
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 32m
Fri 11/276:00 am -
1 stop4h 24m
Deal found 11/2![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/297:24 pm -
1 stop4h 37m
Sun 12/65:02 am -
1 stop3h 50m
Deal found 11/1![American Airlines logo]()
$364
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:00 am -
1 stop4h 42m
Tue 12/296:58 pm -
1 stop3h 47m
Deal found 11/2![United Airlines logo]()
$330
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:00 am -
2 stops9h 35m
Sun 11/224:50 pm -
1 stop5h 15m
Deal found 11/3![Southwest logo]()
$420
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:45 pm -
1 stop4h 13m
Sat 11/213:00 pm -
1 stop4h 16m
Deal found 11/1![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:28 pm -
1 stop3h 56m
Sat 11/285:11 am -
1 stop6h 43m
Deal found 10/31![American Airlines logo]()
$467
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:25 am -
1 stop4h 40m
Tue 11/242:20 pm -
1 stop8h 15m
Deal found 11/4![Southwest logo]()
$425
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:50 pm -
1 stop4h 08m
Sat 11/213:00 pm -
1 stop6h 35m
Deal found 11/2![United Airlines logo]()
$370
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:30 pm -
1 stop3h 25m
Thu 11/198:12 pm -
1 stop3h 42m
Deal found 10/31![American Airlines logo]()
$515
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/510:54 am -
1 stop5h 25m
Wed 12/91:36 pm -
1 stop7h 05m
Deal found 11/2![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/24:30 pm -
1 stop7h 14m
Wed 12/96:00 am -
1 stop4h 19m
Deal found 11/4![United Airlines logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/193:00 pm -
1 stop21h 20m
Tue 11/243:11 pm -
2 stops29h 19m
Deal found 11/2![Allegiant Air logo]()
$817
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
1 stop6h 18m
Sat 12/125:00 pm -
1 stop4h 48m
Deal found 11/4![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/179:55 am -
1 stop4h 39m
Sat 11/218:30 am -
1 stop3h 49m
Deal found 11/2![United Airlines logo]()
$415
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:24 pm -
1 stop46h 34m
Mon 11/236:28 pm -
1 stop43h 00m
Deal found 11/4![American Airlines logo]()
$704
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:00 am -
1 stop4h 10m
Sun 11/225:28 pm -
1 stop4h 27m
Deal found 11/3![United Airlines logo]()
$415
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am -
1 stop4h 46m
Sat 11/286:00 am -
1 stop4h 24m
Deal found 11/1![United Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:00 am -
1 stop4h 35m
Mon 11/235:41 pm -
1 stop5h 15m
Deal found 11/4![United Airlines logo]()
$429
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/173:14 pm -
1 stop6h 37m
Sat 11/211:34 pm -
1 stop7h 25m
Deal found 11/2![United Airlines logo]()
$429
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated November 5, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:11 am -
1 stop6h 04m
Tue 11/248:05 pm -
1 stop4h 14m
Deal found 11/2![American Airlines logo]()
$324
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 32m
Fri 11/276:00 am -
1 stop4h 24m
Deal found 11/2![United Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:28 pm -
1 stop3h 56m
Fri 12/47:20 pm -
1 stop4h 56m
Deal found 11/2![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:28 pm -
1 stop3h 56m
Sun 12/65:17 am -
1 stop5h 07m
Deal found 11/1![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:15 am -
1 stop4h 35m
Wed 12/97:30 am -
1 stop6h 44m
Deal found 11/4![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/29:23 am -
1 stop7h 33m
Wed 12/91:50 pm -
1 stop5h 11m
Deal found 11/4![American Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/33:30 pm -
1 stop6h 30m
Sun 12/139:35 am -
1 stop9h 00m
Deal found 11/3![Southwest logo]()
$304
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:54 am -
1 stop7h 05m
Mon 12/76:29 pm -
1 stop5h 30m
Deal found 11/2![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:05 am -
1 stop6h 17m
Mon 12/75:40 pm -
1 stop4h 08m
Deal found 11/2![United Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop8h 20m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/4![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/131:15 pm -
1 stop3h 50m
Tue 12/159:40 am -
1 stop4h 34m
Deal found 11/3![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/226:00 am -
1 stop4h 42m
Tue 12/296:58 pm -
1 stop3h 47m
Deal found 11/2![United Airlines logo]()
$330
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This CheapOair deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:39 pm -
1 stop14h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Frontier logo]()
$130
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:31 pm -
1 stop4h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$136
This Southwest deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
2 stops7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Southwest logo]()
$146
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/139:07 am -
2 stops26h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$152
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/221:59 pm -
1 stop6h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$170
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/27:14 am -
1 stop6h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$244
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/299:35 pm -
1 stop4h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/109:23 am -
1 stop7h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![American Airlines logo]()
$254
This Kiwi.com deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:29 pm -
2 stops25h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![Multiple Airlines logo]()
$255
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:14 pm -
1 stop5h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:55 pm -
1 stop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Delta logo]()
$275
This Southwest deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
2 stops7h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Southwest logo]()
$280
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated November 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $271 (United Airlines) |
One-way from | $130 (CheapOair) |
Popular in | February |
Cheapest in | May |
Average price | $381 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 12/13
8:39 pm-10:57 am
1 stop14h 18m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 12/2
7:31 pm-12:02 am
1 stop4h 31m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 12/2
6:00 am-1:45 pm
2 stops7h 45m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$146
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 12/13
9:07 am-11:17 am
2 stops26h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
Cedar RapidsSt. Louis
CID Cedar Rapids - STL Lambert-St Louis
CIDSTL
Cedar Rapids
Sun 11/22
1:59 pm-8:04 pm
1 stop6h 05m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$170
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Sun 11/29
9:35 pm-1:54 am
1 stop4h 19m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$244
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Tue 12/1
8:28 pm-12:24 am
1 stop3h 56m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$244
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Fri 12/11
8:24 pm-12:36 am
1 stop4h 12m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$244
Des MoinesSpringfield
DSM Des Moines - SGF Springfield-Branson
DSMSGF
Des Moines
Thu 12/10
9:23 am-4:56 pm
1 stop7h 33m
Springfield-Branson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
Cedar RapidsSt. Louis
CID Cedar Rapids - STL Lambert-St Louis
CIDSTL
Cedar Rapids
Sun 11/15
6:14 pm-11:55 pm
1 stop5h 41m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$258
Showing 1-10 of 51 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
CID-MCI
CID-STL
DSM-SGF
DSM-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
CID-MCI
CID-STL
DSM-SGF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 5, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Crew
8.5
Overall
7.8
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$180 | Average$331 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$244 | Average$379 | FlexibilityNo cancel fee | On-time69% |