$82+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Apr 20 — Apr 271
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 21, 2026.
This Booking.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:36 pm
CID
- MCI
1 stop23h 30m
Frontier
Mon 5/112:34 pm
MCI
- CID
1 stop22h 32m
Frontier
Deal found 3/15![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Mon 5/118:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Deal found 3/18![Frontier logo]()
$235
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$277
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:58 pm
OMA
- COU
1 stop4h 02m
American Airlines
Sat 4/46:00 am
COU
- OMA
1 stop6h 40m
American Airlines
Deal found 3/16![American Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:07 pm
DSM
- STL
2 stops21h 29m
Multiple Airlines
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:31 pm
DSM
- STL
1 stop5h 05m
Delta
Tue 4/217:25 am
STL
- DSM
1 stop6h 30m
Delta
Deal found 3/19![Delta logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$281
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 21, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 21, 2026.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:58 pm
OMA
- COU
1 stop4h 02m
American Airlines
Sat 4/46:00 am
COU
- OMA
1 stop6h 40m
American Airlines
Deal found 3/16![American Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:55 am
DSM
- STL
2 stops6h 05m
Southwest
Wed 4/226:35 am
STL
- DSM
1 stop7h 30m
Southwest
Deal found 3/19![Southwest logo]()
$284
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:23 pm
DSM
- STL
1 stop6h 51m
Delta
Tue 4/2112:23 pm
STL
- DSM
1 stop3h 18m
Delta
Deal found 3/19![Delta logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:05 pm
OMA
- COU
1 stop4h 56m
United Airlines
Sun 4/53:23 pm
COU
- OMA
1 stop6h 48m
United Airlines
Deal found 3/17![United Airlines logo]()
$298
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:01 pm
OMA
- MCI
2 stops17h 28m
Multiple Airlines
Mon 4/202:15 pm
MCI
- OMA
1 stop5h 58m
Multiple Airlines
Deal found 3/15![Multiple Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:00 am
CID
- MCI
1 stop3h 42m
American Airlines
Sat 4/46:40 am
MCI
- CID
1 stop5h 57m
American Airlines
Deal found 3/16![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/125:30 am
DSM
- STL
1 stop6h 00m
Southwest
Sat 5/165:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/18![Southwest logo]()
$293
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:05 pm
OMA
- COU
1 stop7h 28m
United Airlines
Tue 4/711:30 am
COU
- OMA
1 stop4h 09m
United Airlines
Deal found 3/19![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:10 am
DSM
- STL
2 stops9h 22m
Delta
Mon 4/2012:23 pm
STL
- DSM
1 stop3h 18m
Delta
Deal found 3/19![Delta logo]()
$298
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/112:16 pm
OMA
- COU
1 stop5h 44m
American Airlines
Sun 4/56:00 am
COU
- OMA
1 stop5h 45m
American Airlines
Deal found 3/17![American Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:23 pm
DSM
- STL
1 stop6h 51m
Delta
Fri 4/245:35 pm
STL
- DSM
1 stop3h 37m
Delta
Deal found 3/19![Delta logo]()
$298
This Southwest deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/114:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Sat 5/165:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/18![Southwest logo]()
$307
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/236:37 pm
LSE
- STL
1 stop5h 09m
American Airlines
Sun 4/268:03 pm
STL
- LSE
1 stop3h 51m
American Airlines
Deal found 3/17![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/167:00 pm
OMA
- SGF
1 stop5h 36m
United Airlines
Thu 4/231:33 pm
SGF
- OMA
1 stop6h 54m
United Airlines
Deal found 3/19![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:31 pm
DSM
- STL
1 stop5h 05m
Delta
Mon 4/2012:23 pm
STL
- DSM
1 stop3h 18m
Delta
Deal found 3/19![Delta logo]()
$307
This Southwest deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/275:25 am
DSM
- STL
2 stops9h 30m
Southwest
Tue 5/51:15 pm
STL
- DSM
2 stops8h 55m
Southwest
Deal found 3/17![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:37 pm
LSE
- STL
1 stop5h 09m
American Airlines
Wed 4/155:51 am
STL
- LSE
1 stop3h 44m
American Airlines
Deal found 3/20![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:05 am
OMA
- SGF
1 stop6h 41m
United Airlines
Sat 4/46:00 am
SGF
- OMA
1 stop4h 35m
United Airlines
Deal found 3/20![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/155:21 pm
OMA
- STL
1 stop5h 53m
Delta
Wed 4/225:35 pm
STL
- OMA
1 stop5h 14m
Delta
Deal found 3/19![Delta logo]()
$311
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:35 am
DSM
- STL
1 stop4h 55m
Southwest
Sun 5/105:25 am
STL
- DSM
1 stop6h 00m
Southwest
Deal found 3/16![Southwest logo]()
$312
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1010:11 pm
DSM
- MCI
2 stops21h 47m
Multiple Airlines
Sun 4/1212:24 pm
MCI
- DSM
1 stop9h 42m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:40 am
LSE
- STL
1 stop6h 07m
American Airlines
Sun 5/105:51 am
STL
- LSE
1 stop3h 44m
American Airlines
Deal found 3/19![American Airlines logo]()
$298
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:05 am
OMA
- STL
Nonstop1h 15m
Southwest
Wed 4/228:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/16![Southwest logo]()
$313
This Delta deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 pm
DSM
- STL
1 stop6h 38m
Delta
Sat 4/116:00 am
STL
- DSM
1 stop4h 48m
Delta
Deal found 3/18![Delta logo]()
$316
This United Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:52 pm
OMA
- COU
1 stop7h 11m
United Airlines
Wed 4/293:23 pm
COU
- OMA
1 stop6h 48m
United Airlines
Deal found 3/16![United Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/110:21 am
DSM
- MCI
1 stop21h 43m
Multiple Airlines
Sun 4/58:28 pm
MCI
- DSM
1 stop22h 46m
Multiple Airlines
Deal found 3/17![Multiple Airlines logo]()
$434
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:19 am
OMA
- SGF
1 stop6h 16m
American Airlines
Sat 4/410:39 am
SGF
- OMA
1 stop4h 28m
American Airlines
Deal found 3/16![American Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/125:10 am
DSM
- STL
1 stop4h 20m
Southwest
Tue 7/145:55 pm
STL
- DSM
1 stop4h 50m
Southwest
Deal found 3/16![Southwest logo]()
$317
This United Airlines deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/78:00 am
CID
- MCI
1 stop6h 25m
United Airlines
Sat 4/111:05 pm
MCI
- CID
1 stop5h 59m
United Airlines
Deal found 3/15![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:29 pm
LSE
- MCI
1 stop4h 15m
American Airlines
Thu 4/97:50 pm
MCI
- LSE
1 stop4h 04m
American Airlines
Deal found 3/17![American Airlines logo]()
$303
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated March 21, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated March 21, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:58 pm
OMA
- COU
1 stop4h 02m
American Airlines
Sat 4/46:00 am
COU
- OMA
1 stop6h 40m
American Airlines
Deal found 3/16![American Airlines logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$239
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:59 pm
OMA
- STL
2 stops33h 51m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$244
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:07 pm
DSM
- STL
2 stops21h 29m
Multiple Airlines
Thu 4/238:06 pm
STL
- DSM
1 stop17h 03m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:31 pm
DSM
- STL
1 stop5h 05m
Delta
Tue 4/217:25 am
STL
- DSM
1 stop6h 30m
Delta
Deal found 3/19![Delta logo]()
$279
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/145:05 pm
OMA
- COU
1 stop4h 56m
United Airlines
Tue 4/218:00 am
COU
- OMA
1 stop6h 20m
United Airlines
Deal found 3/17![United Airlines logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Sat 4/258:17 pm
STL
- OMA
1 stop23h 56m
Frontier
Deal found 3/19![Frontier logo]()
$197
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Thu 4/238:06 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/19![Frontier logo]()
$202
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated March 21, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated March 21, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Deal found 3/20![Frontier logo]()
$82
This Expedia deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/20![Frontier logo]()
$90
This Frontier deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/17![Frontier logo]()
$91
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Deal found 3/20![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/18![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 3/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/16![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/168:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/17![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/198:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Deal found 3/20![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:58 pm
OMA
- STL
2 stops33h 52m
Frontier
Deal found 3/20![Frontier logo]()
$124
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/17![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 3/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/138:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 3/15![Frontier logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/188:19 pm
OMA
- STL
2 stops21h 47m
Frontier
Deal found 3/17![Frontier logo]()
$129
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated March 21, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $197 (Kiwi.com) |
One-way from | $82 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $243 |
Good round-trip deal | $105 or less |
Good one-way deal | $242 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Tue 3/31
1:58 pm-6:00 pm
1 stop4h 02m
Columbia Regional
Sat 4/4
6:00 am-12:40 pm
1 stop6h 40m
$278
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 4/15
6:55 am-1:00 pm
2 stops6h 05m
Lambert-St Louis
Wed 4/22
6:35 am-2:05 pm
1 stop7h 30m
$284
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Tue 3/31
5:00 am-8:42 am
1 stop3h 42m
Kansas City
Sat 4/4
6:40 am-12:37 pm
1 stop5h 57m
$289
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 4/13
4:23 pm-11:14 pm
1 stop6h 51m
Lambert-St Louis
Tue 4/21
12:23 pm-3:41 pm
1 stop3h 18m
$293
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 5/12
5:30 am-11:30 am
1 stop6h 00m
Lambert-St Louis
Sat 5/16
5:40 am-11:30 am
1 stop5h 50m
$293
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Wed 4/1
5:05 pm-10:01 pm
1 stop4h 56m
Columbia Regional
Sun 4/5
3:23 pm-10:11 pm
1 stop6h 48m
$298
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Fri 4/3
5:05 pm-12:33 am
1 stop7h 28m
Columbia Regional
Tue 4/7
11:30 am-3:39 pm
1 stop4h 09m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 4/14
6:10 am-3:32 pm
2 stops9h 22m
Lambert-St Louis
Mon 4/20
12:23 pm-3:41 pm
1 stop3h 18m
$298
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Wed 4/1
12:16 pm-6:00 pm
1 stop5h 44m
Columbia Regional
Sun 4/5
6:00 am-11:45 am
1 stop5h 45m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 4/14
4:23 pm-11:14 pm
1 stop6h 51m
Lambert-St Louis
Fri 4/24
5:35 pm-9:12 pm
1 stop3h 37m
$298
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
OMA-STL
CID-MCI
OMA-MCI
LSE-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
OMA-STL
CID-MCI
OMA-MCI
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $93). Flying from Iowa to Missouri in January is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 21, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Boarding
8.1
Overall
8.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on March 21, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 21, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$394 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$297 | FlexibilityNo cancel fee | On-time71% |