$152+ Cheap flights from Iowa to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This CheapOair deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:39 pm -
1 stop14h 18m
Wed 12/167:54 pm -
1 stop23h 37m
Deal found 11/9![Frontier logo]()
$260
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
1 stop4h 22m
Fri 12/116:30 am -
1 stop6h 09m
Deal found 11/5![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
1 stop6h 35m
Sat 1/166:45 am -
1 stop7h 55m
Deal found 11/5![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:53 pm -
1 stop6h 33m
Wed 12/96:03 am -
1 stop4h 18m
Deal found 11/9![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
2 stops7h 45m
Wed 12/92:35 pm -
1 stop6h 15m
Deal found 11/9![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop5h 00m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/9![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:00 am -
1 stop3h 49m
Tue 12/86:00 am -
1 stop4h 20m
Deal found 11/6![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:54 pm -
1 stop6h 04m
Sat 12/51:43 pm -
1 stop6h 11m
Deal found 11/9![American Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:17 pm -
1 stop4h 42m
Mon 12/145:17 am -
1 stop5h 07m
Deal found 11/8![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 pm -
1 stop6h 24m
Sat 11/286:00 am -
1 stop4h 20m
Deal found 11/6![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:03 am -
1 stop4h 09m
Sun 11/295:00 am -
1 stop4h 06m
Deal found 11/7![United Airlines logo]()
$334
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:03 am -
1 stop6h 15m
Sat 11/283:00 pm -
1 stop6h 35m
Deal found 11/9![United Airlines logo]()
$338
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
1 stop6h 35m
Sat 1/166:45 am -
1 stop7h 55m
Deal found 11/5![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:00 am -
1 stop3h 49m
Tue 12/86:00 am -
1 stop4h 20m
Deal found 11/6![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/168:29 pm -
1 stop3h 28m
Sun 1/175:51 pm -
1 stop6h 19m
Deal found 11/8![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/168:00 am -
1 stop6h 28m
Sun 1/175:06 pm -
1 stop4h 25m
Deal found 11/8![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:00 am -
2 stops10h 05m
Sat 1/910:45 am -
2 stops9h 35m
Deal found 11/5![Southwest logo]()
$281
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:39 pm -
1 stop6h 00m
Tue 1/126:04 am -
1 stop4h 09m
Deal found 11/10![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:17 pm -
1 stop4h 42m
Mon 12/145:17 am -
1 stop5h 07m
Deal found 11/8![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:03 am -
1 stop4h 09m
Sun 11/295:00 am -
1 stop4h 06m
Deal found 11/7![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop5h 00m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/9![Southwest logo]()
$318
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:15 am -
1 stop4h 45m
Mon 12/146:03 am -
1 stop4h 17m
Deal found 11/9![Delta logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:03 am -
1 stop6h 15m
Sat 11/283:00 pm -
1 stop6h 35m
Deal found 11/9![United Airlines logo]()
$338
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2112:24 pm -
1 stop4h 35m
Wed 11/256:00 am -
1 stop4h 23m
Deal found 11/5![American Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
2 stops9h 35m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/9![Southwest logo]()
$323
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:00 am -
1 stop4h 32m
Sun 11/295:00 am -
1 stop4h 06m
Deal found 11/7![United Airlines logo]()
$344
This Delta deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:00 am -
1 stop3h 43m
Sat 11/286:00 am -
1 stop4h 20m
Deal found 11/5![Delta logo]()
$364
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/198:28 pm -
1 stop3h 33m
Sat 11/215:50 am -
1 stop6h 04m
Deal found 11/9![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop6h 10m
Sat 11/286:50 pm -
1 stop4h 06m
Deal found 11/9![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/114:25 pm -
2 stops8h 10m
Sun 12/139:35 am -
1 stop9h 00m
Deal found 11/9![Southwest logo]()
$376
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:30 am -
1 stop4h 58m
Mon 12/73:04 pm -
1 stop6h 21m
Deal found 11/7![United Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:05 am -
1 stop4h 40m
Wed 11/253:00 pm -
1 stop6h 55m
Deal found 11/6![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops7h 50m
Fri 12/114:30 pm -
2 stops6h 35m
Deal found 11/5![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/258:03 am -
1 stop4h 07m
Sun 11/295:00 am -
1 stop4h 06m
Deal found 11/5![United Airlines logo]()
$358
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/64:25 pm -
2 stops7h 30m
Sun 12/138:30 am -
2 stops10h 05m
Deal found 11/8![Southwest logo]()
$410
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/1310:00 am -
1 stop4h 34m
Mon 11/165:34 pm -
1 stop5h 22m
Deal found 11/6![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/1411:27 am -
1 stop6h 49m
Wed 12/166:30 am -
1 stop4h 07m
Deal found 11/7![United Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
1 stop6h 18m
Sat 12/125:00 pm -
1 stop4h 48m
Deal found 11/5![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:05 am -
1 stop6h 17m
Tue 12/156:30 am -
1 stop3h 49m
Deal found 11/7![United Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/216:00 am -
1 stop6h 12m
Wed 11/254:39 pm -
1 stop7h 04m
Deal found 11/6![United Airlines logo]()
$422
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop4h 36m
Sat 11/286:40 pm -
1 stop4h 16m
Deal found 11/9![United Airlines logo]()
$424
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop4h 26m
Fri 11/278:45 am -
1 stop5h 40m
Deal found 11/8![United Airlines logo]()
$439
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated November 10, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/218:03 am -
1 stop4h 09m
Sun 11/295:00 am -
1 stop4h 06m
Deal found 11/7![United Airlines logo]()
$334
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:00 pm -
1 stop6h 24m
Sat 11/286:00 am -
1 stop4h 20m
Deal found 11/6![Delta logo]()
$334
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/248:03 am -
1 stop6h 15m
Sat 11/283:00 pm -
1 stop6h 35m
Deal found 11/9![United Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:00 am -
1 stop3h 49m
Tue 12/86:00 am -
1 stop4h 20m
Deal found 11/6![Delta logo]()
$319
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:17 pm -
1 stop4h 42m
Mon 12/145:17 am -
1 stop5h 07m
Deal found 11/8![American Airlines logo]()
$329
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/31:54 pm -
1 stop6h 04m
Sat 12/51:43 pm -
1 stop6h 11m
Deal found 11/9![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:00 am -
1 stop4h 22m
Fri 12/116:30 am -
1 stop6h 09m
Deal found 11/5![United Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/84:53 pm -
1 stop6h 33m
Wed 12/96:03 am -
1 stop4h 18m
Deal found 11/9![Delta logo]()
$303
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
2 stops7h 45m
Wed 12/92:35 pm -
1 stop6h 15m
Deal found 11/9![Southwest logo]()
$308
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
1 stop5h 00m
Thu 12/104:40 pm -
1 stop5h 25m
Deal found 11/9![Southwest logo]()
$318
This CheapOair deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/138:39 pm -
1 stop14h 18m
Wed 12/167:54 pm -
1 stop23h 37m
Deal found 11/9![Frontier logo]()
$260
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/253:25 pm -
1 stop6h 35m
Sat 1/166:45 am -
1 stop7h 55m
Deal found 11/5![Southwest logo]()
$276
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:20 am -
1 stop6h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Southwest logo]()
$152
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:53 pm -
1 stop6h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Delta logo]()
$177
This Southwest deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Southwest logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/42:50 pm -
3 stops33h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$242
This American Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:54 pm -
1 stop4h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![American Airlines logo]()
$249
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:04 pm -
1 stop6h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Delta logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:17 pm -
3 stops39h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/116:29 pm -
2 stops25h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:04 pm -
3 stops39h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Multiple Airlines logo]()
$285
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:17 pm -
1 stop4h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/5![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1410:55 am -
1 stop5h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![American Airlines logo]()
$345
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:59 pm -
3 stops45h 58m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$347
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated November 10, 2026.
Round-trip from | $260 (CheapOair) |
|---|---|
One-way from | $152 (Southwest) |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sat 12/5
5:20 am-11:40 am
1 stop6h 20m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 2/17
3:00 pm-9:00 pm
1 stop6h 00m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$152
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 12/4
4:53 pm-11:26 pm
1 stop6h 33m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$177
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Fri 12/11
8:24 pm-12:36 am
1 stop4h 12m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Thu 12/10
1:54 pm-6:50 pm
1 stop4h 56m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
Cedar RapidsSt. Louis
CID Cedar Rapids - STL Lambert-St Louis
CIDSTL
Cedar Rapids
Thu 12/3
5:04 pm-11:26 pm
1 stop6h 22m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$249
Cedar RapidsSt. Louis
CID Cedar Rapids - STL Lambert-St Louis
CIDSTL
Cedar Rapids
Thu 12/3
7:17 pm-10:57 am
3 stops39h 40m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$274
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 12/25
3:25 pm-10:00 pm
1 stop6h 35m
Lambert-St Louis
Sat 1/16
6:45 am-2:40 pm
1 stop7h 55m
$276
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 1/8
8:00 am-6:05 pm
2 stops10h 05m
Lambert-St Louis
Sat 1/9
10:45 am-8:20 pm
2 stops9h 35m
$281
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Fri 12/11
6:29 pm-7:35 pm
2 stops25h 06m
Kansas City
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$283
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
CID-MCI
CID-STL
CID-COU
DSM-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
CID-MCI
CID-STL
CID-COU
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated November 10, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Boarding
8.1
Food
7.2
Comfort
7.8
Crew
8.5
Entertainment
7.8
Overall
7.8
Reviews
1 / 20
6.0
GoodEllen,Oct 2026
GRR - ATL
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on November 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$180 | Average$331 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$244 | Average$379 | FlexibilityNo cancel fee | On-time69% |