$124+ Cheap flights from Iowa to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/16. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Nov 23 — Nov 301
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 24, 2026.
This Frontier deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop14h 35m
Sat 12/57:54 pm -
1 stop23h 56m
Deal found 10/23![Frontier logo]()
$240
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:23 pm -
1 stop4h 36m
Sat 11/218:12 pm -
1 stop4h 07m
Deal found 10/21![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:25 am -
1 stop4h 40m
Wed 12/26:20 am -
1 stop5h 05m
Deal found 10/19![Southwest logo]()
$248
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 20m
Sat 12/58:55 am -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
1 stop6h 25m
Tue 11/172:35 pm -
1 stop6h 15m
Deal found 10/20![Southwest logo]()
$255
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:25 am -
1 stop4h 40m
Sun 11/227:15 pm -
1 stop3h 50m
Deal found 10/20![Southwest logo]()
$288
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:45 pm -
1 stop4h 25m
Thu 11/267:30 am -
1 stop6h 54m
Deal found 10/19![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:00 am -
1 stop5h 53m
Fri 11/2712:40 pm -
1 stop6h 33m
Deal found 10/19![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:00 pm -
1 stop6h 22m
Tue 12/16:03 am -
1 stop4h 17m
Deal found 10/19![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 pm -
1 stop6h 24m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/22![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/227:15 pm -
1 stop3h 30m
Sat 12/265:30 am -
1 stop5h 55m
Deal found 10/22![Southwest logo]()
$331
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:00 am -
1 stop5h 42m
Sat 11/2810:32 am -
1 stop5h 36m
Deal found 10/21![Delta logo]()
$334
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 24, 2026.
This Frontier deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop14h 35m
Sat 12/57:54 pm -
1 stop23h 56m
Deal found 10/23![Frontier logo]()
$240
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 20m
Sat 12/58:55 am -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$252
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/206:45 pm -
1 stop4h 25m
Fri 11/276:40 pm -
1 stop4h 19m
Deal found 10/23![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:15 am -
1 stop5h 40m
Sun 11/226:00 am -
1 stop4h 20m
Deal found 10/21![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/55:00 am -
1 stop4h 48m
Mon 11/96:26 pm -
1 stop5h 13m
Deal found 10/21![American Airlines logo]()
$348
This Kiwi.com deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/189:53 am -
1 stop7h 04m
Thu 1/215:52 pm -
1 stop25h 08m
Deal found 10/19![Allegiant Air logo]()
$426
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:25 am -
1 stop4h 40m
Wed 12/211:55 am -
2 stops10h 10m
Deal found 10/19![Southwest logo]()
$253
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/86:55 am -
1 stop5h 10m
Sat 1/92:30 pm -
1 stop4h 50m
Deal found 10/21![Southwest logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:01 pm -
1 stop26h 49m
Mon 1/116:20 pm -
2 stops18h 03m
Deal found 10/20![Multiple Airlines logo]()
$563
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/46:15 am -
1 stop4h 32m
Tue 2/97:30 am -
1 stop4h 47m
Deal found 10/20![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:00 am -
1 stop5h 53m
Fri 11/2712:40 pm -
1 stop6h 33m
Deal found 10/19![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:00 am -
1 stop5h 53m
Mon 11/305:35 pm -
1 stop5h 31m
Deal found 10/19![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2510:00 am -
1 stop4h 35m
Thu 11/266:00 am -
1 stop4h 24m
Deal found 10/22![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:00 am -
1 stop5h 42m
Thu 11/266:00 am -
1 stop4h 20m
Deal found 10/19![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 39m
Tue 11/101:08 pm -
1 stop4h 20m
Deal found 10/22![United Airlines logo]()
$331
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops7h 40m
Wed 11/188:25 am -
1 stop5h 50m
Deal found 10/20![Southwest logo]()
$336
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:00 pm -
1 stop6h 22m
Sun 11/225:22 pm -
1 stop5h 44m
Deal found 10/20![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
2 stops8h 50m
Wed 11/116:30 am -
1 stop7h 45m
Deal found 10/23![Southwest logo]()
$336
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:45 pm -
1 stop4h 25m
Sat 11/77:35 am -
1 stop6h 49m
Deal found 10/19![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:15 am -
1 stop6h 06m
Wed 12/212:31 pm -
1 stop3h 50m
Deal found 10/19![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 25m
Tue 11/103:10 pm -
1 stop4h 06m
Deal found 10/21![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/1811:00 am -
1 stop3h 41m
Thu 11/266:13 am -
1 stop4h 07m
Deal found 10/19![Delta logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:03 am -
1 stop6h 31m
Mon 11/96:50 pm -
1 stop4h 06m
Deal found 10/21![United Airlines logo]()
$339
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 pm -
1 stop6h 24m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/22![Delta logo]()
$329
This United Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:00 am -
1 stop6h 18m
Wed 11/113:00 pm -
1 stop6h 55m
Deal found 10/22![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:14 am -
1 stop10h 45m
Tue 12/156:15 am -
1 stop12h 46m
Deal found 10/22![American Airlines logo]()
$658
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:45 pm -
1 stop4h 13m
Sat 11/78:00 am -
1 stop6h 24m
Deal found 10/19![United Airlines logo]()
$348
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/127:00 pm -
1 stop4h 08m
Tue 2/163:13 pm -
1 stop5h 27m
Deal found 10/20![United Airlines logo]()
$386
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/226:15 am -
2 stops7h 13m
Tue 12/16:00 am -
1 stop4h 20m
Deal found 10/19![Delta logo]()
$439
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:00 am -
1 stop6h 18m
Sun 12/66:35 pm -
1 stop4h 40m
Deal found 10/20![United Airlines logo]()
$399
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated October 24, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated October 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/47:26 pm -
1 stop4h 33m
Wed 11/185:00 am -
1 stop3h 46m
Deal found 10/20![American Airlines logo]()
$331
This United Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:45 pm -
1 stop4h 25m
Thu 11/267:30 am -
1 stop6h 54m
Deal found 10/19![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 pm -
1 stop6h 24m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/22![Delta logo]()
$329
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
1 stop6h 25m
Tue 11/172:35 pm -
1 stop6h 15m
Deal found 10/20![Southwest logo]()
$255
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:23 pm -
1 stop4h 36m
Sat 11/218:12 pm -
1 stop4h 07m
Deal found 10/21![American Airlines logo]()
$247
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/165:00 pm -
1 stop6h 22m
Tue 12/16:03 am -
1 stop4h 17m
Deal found 10/19![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/205:25 am -
1 stop4h 40m
Sun 11/227:15 pm -
1 stop3h 50m
Deal found 10/20![Southwest logo]()
$288
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/2111:00 am -
1 stop5h 53m
Mon 11/305:35 pm -
1 stop5h 31m
Deal found 10/19![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/235:25 am -
1 stop4h 40m
Wed 12/26:20 am -
1 stop5h 05m
Deal found 10/19![Southwest logo]()
$248
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2411:00 am -
1 stop5h 42m
Sat 11/2810:32 am -
1 stop5h 36m
Deal found 10/21![Delta logo]()
$334
This Frontier deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/268:28 pm -
1 stop14h 35m
Sat 12/57:54 pm -
1 stop23h 56m
Deal found 10/23![Frontier logo]()
$240
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/265:10 am -
2 stops9h 20m
Sat 12/58:55 am -
1 stop4h 45m
Deal found 10/23![Southwest logo]()
$252
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated October 24, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/167:26 pm -
1 stop4h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$124
This Southwest deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:00 am -
2 stops7h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Southwest logo]()
$129
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:25 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/28:30 am -
2 stops28h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Multiple Airlines logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:04 pm -
2 stops43h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops29h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Multiple Airlines logo]()
$191
This United Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:45 pm -
1 stop4h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![United Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:00 am -
2 stops7h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![Southwest logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/1611:39 am -
3 stops47h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Multiple Airlines logo]()
$228
This Delta deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/111:00 am -
1 stop5h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![Delta logo]()
$244
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/910:54 am -
1 stop5h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$244
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/169:25 am -
1 stop7h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![American Airlines logo]()
$254
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated October 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $240 (Frontier) |
One-way from | $124 (American Airlines) |
Popular in | February |
Cheapest in | May |
Average price | $314 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 11/16
7:26 pm-11:59 pm
1 stop4h 33m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$124
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Tue 12/15
3:25 pm-10:00 pm
1 stop6h 35m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$124
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 12/16
6:00 am-1:50 pm
2 stops7h 50m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$129
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 11/15
5:25 am-10:05 am
1 stop4h 40m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$132
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 11/2
8:30 am-1:21 pm
2 stops28h 51m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$148
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 11/16
8:04 pm-3:23 pm
2 stops43h 19m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$185
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 11/15
7:30 am-1:21 pm
2 stops29h 51m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$191
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 11/4
6:45 pm-11:24 pm
1 stop4h 39m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 12/16
11:39 am-10:53 am
3 stops47h 14m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$228
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Thu 11/26
8:28 pm-11:03 am
1 stop14h 35m
Lambert-St Louis
Sat 12/5
7:54 pm-7:50 pm
1 stop23h 56m
$240
Showing 1-10 of 57 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
CID-MCI
DSM-SGF
CID-STL
CID-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
CID-MCI
DSM-SGF
CID-STL
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 24, 2026.
Peruse reviews from past customers who have flown with Southwest,Delta, andUnited Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Comfort
8.0
Food
7.0
Boarding
8.1
Entertainment
7.4
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on October 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 4 airlines flying from Iowa to Missouri
Discover the top 4 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$116 | Average$297 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$180 | Average$331 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$244 | Average$377 | FlexibilityNo cancel fee | On-time69% |