$118+ Cheap flights from Iowa to Missouri
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/24. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Nov 11 — Nov 181
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 12, 2026.
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:26 pm -
1 stop4h 29m
Thu 11/125:01 am -
1 stop3h 45m
Deal found 10/8![American Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:30 pm -
1 stop6h 30m
Fri 11/64:50 pm -
1 stop5h 15m
Deal found 10/7![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
1 stop6h 20m
Sat 11/1410:45 am -
2 stops9h 00m
Deal found 10/10![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/194:15 pm -
1 stop6h 30m
Tue 12/222:35 pm -
2 stops8h 55m
Deal found 10/11![Southwest logo]()
$281
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops8h 10m
Mon 11/162:20 pm -
2 stops7h 45m
Deal found 10/11![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/106:00 am -
1 stop5h 00m
Sun 12/137:15 pm -
1 stop3h 45m
Deal found 10/8![Southwest logo]()
$287
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:10 am -
2 stops8h 45m
Tue 12/2911:40 am -
2 stops11h 50m
Deal found 10/10![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 25m
Sun 11/86:40 pm -
1 stop4h 19m
Deal found 10/10![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:15 am -
1 stop3h 37m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/8![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop3h 29m
Fri 11/135:01 am -
1 stop5h 17m
Deal found 10/9![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
1 stop5h 17m
Sun 11/15:26 pm -
1 stop7h 00m
Deal found 10/11![American Airlines logo]()
$324
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:00 am -
1 stop3h 42m
Fri 11/136:00 am -
1 stop4h 20m
Deal found 10/9![Delta logo]()
$324
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 12, 2026.
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:05 am -
1 stop6h 05m
Tue 11/176:50 pm -
1 stop4h 09m
Deal found 10/11![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/13:30 pm -
1 stop6h 25m
Mon 1/47:15 pm -
1 stop3h 45m
Deal found 10/10![Southwest logo]()
$271
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:55 pm -
1 stop3h 27m
Mon 11/166:13 am -
1 stop4h 06m
Deal found 10/11![Delta logo]()
$271
This American Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:23 am -
1 stop5h 44m
Sat 11/145:30 pm -
1 stop6h 56m
Deal found 10/10![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/76:30 pm -
1 stop4h 50m
Sat 1/99:05 am -
1 stop5h 25m
Deal found 10/9![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/85:55 am -
1 stop5h 25m
Sat 1/910:35 am -
2 stops9h 40m
Deal found 10/9![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/313:30 pm -
1 stop6h 25m
Mon 1/48:25 am -
1 stop4h 45m
Deal found 10/10![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:00 pm -
1 stop6h 24m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/7![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:14 pm -
1 stop6h 10m
Wed 11/115:23 am -
1 stop6h 25m
Deal found 10/7![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:40 pm -
1 stop7h 05m
Tue 12/294:50 pm -
1 stop6h 40m
Deal found 10/10![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/247:00 pm -
1 stop4h 08m
Sat 3/273:15 pm -
1 stop6h 02m
Deal found 10/11![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop3h 29m
Fri 11/135:01 am -
1 stop5h 17m
Deal found 10/9![American Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:00 am -
1 stop3h 42m
Fri 11/136:00 am -
1 stop4h 20m
Deal found 10/9![Delta logo]()
$324
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:00 am -
1 stop5h 00m
Thu 11/124:30 pm -
2 stops6h 35m
Deal found 10/9![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
1 stop5h 17m
Sun 11/15:26 pm -
1 stop7h 00m
Deal found 10/11![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops7h 30m
Mon 11/166:20 am -
1 stop5h 05m
Deal found 10/11![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/247:29 am -
1 stop5h 37m
Wed 10/288:08 pm -
1 stop4h 06m
Deal found 10/9![American Airlines logo]()
$339
This Southwest deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:55 am -
2 stops7h 55m
Sat 1/910:35 am -
2 stops9h 40m
Deal found 10/9![Southwest logo]()
$281
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:35 am -
1 stop7h 08m
Mon 10/261:08 pm -
1 stop5h 02m
Deal found 10/7![United Airlines logo]()
$378
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/116:00 am -
2 stops9h 35m
Tue 11/172:20 pm -
2 stops7h 45m
Deal found 10/11![Southwest logo]()
$286
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop5h 27m
Wed 12/97:36 am -
1 stop6h 55m
Deal found 10/9![United Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop5h 43m
Mon 10/266:50 pm -
1 stop4h 06m
Deal found 10/7![United Airlines logo]()
$484
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:45 pm -
1 stop4h 25m
Thu 11/193:10 pm -
1 stop6h 45m
Deal found 10/10![United Airlines logo]()
$487
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/256:00 am -
1 stop6h 10m
Thu 10/295:00 am -
1 stop5h 24m
Deal found 10/10![United Airlines logo]()
$490
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:34 pm -
1 stop3h 45m
Sun 10/257:29 am -
1 stop4h 24m
Deal found 10/11![American Airlines logo]()
$596
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:00 pm -
1 stop5h 44m
Mon 10/266:45 pm -
1 stop4h 11m
Deal found 10/7![United Airlines logo]()
$498
This American Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/211:58 pm -
1 stop20h 06m
Fri 11/2710:36 am -
1 stop8h 18m
Deal found 10/7![American Airlines logo]()
$619
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:45 am -
1 stop4h 52m
Mon 10/263:10 pm -
1 stop6h 45m
Deal found 10/7![United Airlines logo]()
$533
This United Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/237:55 am -
1 stop4h 18m
Tue 10/275:00 am -
1 stop5h 24m
Deal found 10/8![United Airlines logo]()
$534
This United Airlines deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/226:30 am -
1 stop5h 39m
Mon 10/261:33 pm -
1 stop7h 26m
Deal found 10/7![United Airlines logo]()
$565
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated October 12, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated October 12, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:00 am -
1 stop3h 42m
Fri 11/136:00 am -
1 stop4h 20m
Deal found 10/9![Delta logo]()
$324
This United Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:00 am -
1 stop4h 39m
Wed 10/283:00 pm -
1 stop6h 55m
Deal found 10/9![United Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:10 pm -
1 stop4h 40m
Sun 11/19:35 am -
1 stop9h 00m
Deal found 10/8![Southwest logo]()
$327
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/312:01 pm -
1 stop5h 17m
Sun 11/15:26 pm -
1 stop7h 00m
Deal found 10/11![American Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/43:30 pm -
1 stop6h 30m
Fri 11/64:50 pm -
1 stop5h 15m
Deal found 10/7![Southwest logo]()
$266
This American Airlines deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:26 pm -
1 stop4h 29m
Thu 11/125:01 am -
1 stop3h 45m
Deal found 10/8![American Airlines logo]()
$235
This United Airlines deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:45 pm -
1 stop4h 25m
Sun 11/86:40 pm -
1 stop4h 19m
Deal found 10/10![United Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 10/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:30 pm -
1 stop3h 29m
Fri 11/135:01 am -
1 stop5h 17m
Deal found 10/9![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:20 am -
1 stop6h 20m
Sat 11/1410:45 am -
2 stops9h 00m
Deal found 10/10![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/94:25 pm -
2 stops8h 10m
Mon 11/162:20 pm -
2 stops7h 45m
Deal found 10/11![Southwest logo]()
$286
This Delta deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/126:15 am -
1 stop3h 37m
Sun 11/156:00 am -
1 stop4h 20m
Deal found 10/8![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/134:25 pm -
1 stop3h 25m
Sun 11/157:15 pm -
1 stop3h 50m
Deal found 10/7![Southwest logo]()
$328
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated October 12, 2026.
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/245:10 am -
1 stop4h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$118
This CheapOair deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Fri 10/308:30 pm -
1 stop22h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Frontier logo]()
$130
This Delta deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:55 pm -
1 stop3h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Delta logo]()
$136
This Southwest deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/304:30 pm -
2 stops8h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Southwest logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:30 am -
2 stops29h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Multiple Airlines logo]()
$140
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:25 am -
2 stops8h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Southwest logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/188:28 am -
2 stops28h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$164
This Southwest deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:25 am -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![Southwest logo]()
$165
This CheapOair deal was found by Cheapflights users on 10/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:25 pm -
1 stop22h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/10![Frontier logo]()
$191
This Southwest deal was found by Cheapflights users on 10/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:10 pm -
1 stop4h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/7![Southwest logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 10/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/261:24 pm -
2 stops30h 23m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/8![Multiple Airlines logo]()
$204
This American Airlines deal was found by Cheapflights users on 10/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:00 am -
1 stop6h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/11![American Airlines logo]()
$244
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated October 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $235 (American Airlines) |
One-way from | $118 (Southwest) |
Popular in | February |
Cheapest in | May |
Average price | $314 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Tue 11/24
5:10 am-9:25 am
1 stop4h 15m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$118
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 10/30
8:30 pm-7:14 pm
1 stop22h 44m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$130
Quickest round-trip
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Wed 11/11
7:55 pm-11:22 pm
1 stop3h 27m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 11/13
8:30 pm-7:14 pm
1 stop22h 44m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 10/30
4:30 pm-12:40 am
2 stops8h 10m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$137
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 11/15
7:30 am-1:21 pm
2 stops29h 51m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$140
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Thu 11/12
5:25 am-2:05 pm
2 stops8h 40m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$141
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 10/18
8:28 am-1:21 pm
2 stops28h 53m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$164
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 11/15
6:05 am-12:10 pm
1 stop6h 05m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Sun 11/15
5:25 am-10:05 am
1 stop4h 40m
Lambert-St Louis
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$165
Showing 1-10 of 54 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
DSM-SGF
CID-MCI
CID-STL
DSM-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
DSM-SGF
CID-MCI
CID-STL
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, December is the cheapest month in which you can book a flight from Iowa to Missouri (average of $264). Flying from Iowa to Missouri in September is currently the most expensive (average of $500). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated October 12, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Food
7.0
Overall
7.9
Entertainment
7.5
Comfort
8.0
Boarding
8.1
Crew
8.6
Reviews
1 / 20
8.0
ExcellentPatricia,Oct 2026
DAL - TPA
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on October 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$116 | Average$297 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$418 | FlexibilityNo cancel fee | On-time69% |