$66+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MCI
Jul 4 — Jul 111
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
- MCI
1 stop12h 22m
Frontier
Tue 7/71:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/1![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MCI
1 stop22h 44m
Frontier
Tue 7/74:58 pm
MCI
- DSM
1 stop20h 36m
Frontier
Deal found 6/3![Frontier logo]()
$222
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 7/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/3![Frontier logo]()
$242
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:40 am
DSM
- STL
1 stop4h 50m
Southwest
Mon 8/172:00 pm
STL
- DSM
1 stop7h 15m
Southwest
Deal found 5/31![Southwest logo]()
$255
This Booking.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Sat 7/118:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 5/30![Frontier logo]()
$256
This Mytrip deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 6/308:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Deal found 5/30![Frontier logo]()
$259
This Booking.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/52:19 pm
DSM
- STL
1 stop5h 04m
Frontier
Thu 8/68:08 pm
STL
- DSM
1 stop17h 26m
Frontier
Deal found 6/2![Frontier logo]()
$261
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Mon 8/108:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/3![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MCI
1 stop22h 44m
Multiple Airlines
Wed 7/86:07 pm
MCI
- DSM
2 stops29h 00m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$278
This Mytrip deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/2![Frontier logo]()
$278
This Booking.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/2![Frontier logo]()
$280
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/68:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Sun 8/98:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/3![Frontier logo]()
$282
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
- MCI
1 stop12h 22m
Frontier
Tue 7/71:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/1![Frontier logo]()
$215
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/135:40 am
DSM
- STL
1 stop4h 50m
Southwest
Mon 8/172:00 pm
STL
- DSM
1 stop7h 15m
Southwest
Deal found 5/31![Southwest logo]()
$255
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:30 pm
CID
- MCI
1 stop4h 43m
United Airlines
Sat 6/206:41 pm
MCI
- CID
1 stop4h 10m
United Airlines
Deal found 5/31![United Airlines logo]()
$309
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/55:56 pm
DSM
- STL
1 stop5h 30m
Delta
Sun 8/96:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 5/30![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:09 pm
DSM
- STL
1 stop5h 07m
American Airlines
Sun 6/288:14 pm
STL
- DSM
1 stop4h 21m
American Airlines
Deal found 5/30![American Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/21:55 pm
CID
- MCI
1 stop23h 05m
Multiple Airlines
Thu 7/161:45 pm
MCI
- CID
2 stops31h 35m
Multiple Airlines
Deal found 6/2![Multiple Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:10 am
DSM
- STL
2 stops8h 20m
Southwest
Thu 8/66:05 am
STL
- DSM
1 stop5h 20m
Southwest
Deal found 6/2![Southwest logo]()
$313
This Booking.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/158:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/1![Frontier logo]()
$323
This Delta deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:03 pm
DSM
- STL
1 stop4h 01m
Delta
Sat 7/43:57 pm
STL
- DSM
1 stop5h 11m
Delta
Deal found 5/30![Delta logo]()
$325
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
ALO
- STL
1 stop15h 32m
American Airlines
Tue 7/79:08 am
STL
- ALO
1 stop39h 21m
American Airlines
Deal found 6/1![American Airlines logo]()
$329
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:30 am
CID
- MCI
1 stop5h 50m
United Airlines
Sat 10/106:00 am
MCI
- CID
1 stop6h 56m
United Airlines
Deal found 5/30![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/276:55 pm
DSM
- STL
1 stop4h 50m
Southwest
Sat 7/410:15 am
STL
- DSM
2 stops9h 05m
Southwest
Deal found 5/30![Southwest logo]()
$330
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/218:15 pm
OMA
- MCI
1 stop16h 45m
Frontier
Sun 7/261:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 5/30![Frontier logo]()
$347
This United Airlines deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/226:00 am
CID
- MCI
1 stop6h 20m
United Airlines
Tue 8/251:43 pm
MCI
- CID
1 stop7h 10m
United Airlines
Deal found 5/31![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:15 am
OMA
- STL
Nonstop1h 15m
Southwest
Tue 7/78:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/3![Southwest logo]()
$335
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/275:17 am
OMA
- SGF
1 stop6h 59m
American Airlines
Wed 7/16:43 pm
SGF
- OMA
1 stop4h 42m
American Airlines
Deal found 6/3![American Airlines logo]()
$380
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:40 pm
OMA
- SGF
1 stop4h 47m
United Airlines
Sat 6/206:35 pm
SGF
- OMA
1 stop5h 09m
United Airlines
Deal found 6/1![United Airlines logo]()
$351
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/154:40 pm
DSM
- STL
2 stops6h 05m
Southwest
Tue 6/1610:15 am
STL
- DSM
2 stops12h 30m
Southwest
Deal found 6/1![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:00 am
OMA
- SGF
1 stop4h 37m
United Airlines
Sat 10/246:25 am
SGF
- OMA
1 stop7h 43m
United Airlines
Deal found 5/30![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:41 pm
LSE
- MCI
1 stop6h 38m
American Airlines
Tue 7/217:46 pm
MCI
- LSE
1 stop4h 13m
American Airlines
Deal found 6/3![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:40 am
DSM
- MCI
1 stop7h 25m
Southwest
Sat 11/214:20 pm
MCI
- DSM
1 stop6h 35m
Southwest
Deal found 6/1![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/282:55 pm
OMA
- SGF
1 stop6h 33m
United Airlines
Sat 10/316:15 pm
SGF
- OMA
1 stop4h 59m
United Airlines
Deal found 6/3![United Airlines logo]()
$359
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/208:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Thu 7/301:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 5/31![Frontier logo]()
$448
This American Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/265:54 am
LSE
- STL
1 stop4h 26m
American Airlines
Tue 9/295:00 am
STL
- LSE
1 stop6h 22m
American Airlines
Deal found 6/1![American Airlines logo]()
$408
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/171:30 pm
DSM
- STL
1 stop6h 50m
Southwest
Fri 7/246:30 pm
STL
- DSM
1 stop5h 05m
Southwest
Deal found 6/2![Southwest logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/2612:26 pm
LSE
- STL
1 stop4h 22m
American Airlines
Wed 9/307:21 am
STL
- LSE
1 stop4h 01m
American Airlines
Deal found 6/2![American Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/246:30 am
CID
- MCI
1 stop3h 59m
United Airlines
Sun 7/266:41 pm
MCI
- CID
1 stop4h 01m
United Airlines
Deal found 6/1![United Airlines logo]()
$377
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/24:40 pm
DSM
- STL
2 stops6h 05m
Southwest
Sat 7/41:55 pm
STL
- DSM
1 stop6h 20m
Southwest
Deal found 6/2![Southwest logo]()
$350
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/94:40 pm
DSM
- MCI
2 stops7h 35m
Southwest
Sun 7/127:20 pm
MCI
- DSM
1 stop4h 30m
Southwest
Deal found 6/3![Southwest logo]()
$352
This American Airlines deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/111:52 am
LSE
- STL
1 stop4h 41m
American Airlines
Tue 7/76:55 am
STL
- LSE
1 stop4h 36m
American Airlines
Deal found 6/2![American Airlines logo]()
$453
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated June 4, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated June 4, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/238:25 pm
OMA
- STL
1 stop22h 58m
Frontier
Fri 6/267:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Deal found 6/3![Frontier logo]()
$302
This Mytrip deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/268:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 6/308:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Deal found 5/30![Frontier logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
- MCI
1 stop12h 22m
Frontier
Tue 7/71:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Deal found 6/1![Frontier logo]()
$215
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MCI
1 stop22h 44m
Frontier
Tue 7/74:58 pm
MCI
- DSM
1 stop20h 36m
Frontier
Deal found 6/3![Frontier logo]()
$222
This Booking.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/18:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Tue 7/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/3![Frontier logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/12:16 pm
DSM
- MCI
1 stop22h 44m
Multiple Airlines
Wed 7/86:07 pm
MCI
- DSM
2 stops29h 00m
Multiple Airlines
Deal found 6/3![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/16:50 am
DSM
- STL
1 stop3h 38m
Delta
Wed 7/83:57 pm
STL
- DSM
1 stop5h 11m
Delta
Deal found 6/3![Delta logo]()
$293
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:20 am
DSM
- STL
2 stops9h 30m
Southwest
Wed 7/81:45 pm
STL
- DSM
1 stop8h 00m
Southwest
Deal found 6/3![Southwest logo]()
$303
This Booking.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/2![Frontier logo]()
$280
This Mytrip deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/38:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/2![Frontier logo]()
$278
This Booking.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/78:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Sat 7/118:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 5/30![Frontier logo]()
$256
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:20 am
DSM
- STL
2 stops9h 30m
Southwest
Tue 7/215:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Deal found 5/31![Southwest logo]()
$298
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:29 pm
OMA
- STL
1 stop22h 54m
Frontier
Deal found 6/3![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 6/3![Frontier logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/4![Frontier logo]()
$85
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/2![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:25 pm
OMA
- STL
1 stop22h 58m
Frontier
Deal found 5/31![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/3![Frontier logo]()
$113
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/266:48 am
OMA
- STL
1 stop6h 06m
American Airlines
Deal found 5/30![American Airlines logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 6/1![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:29 pm
OMA
- STL
1 stop22h 54m
Frontier
Deal found 5/30![Frontier logo]()
$122
This Booking.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/301:55 pm
CID
- MCI
1 stop18h 52m
Frontier
Deal found 6/1![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/286:00 am
DSM
- STL
2 stops12h 36m
Multiple Airlines
Deal found 6/1![Multiple Airlines logo]()
$142
This American Airlines deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/36:33 pm
DSM
- STL
1 stop5h 43m
American Airlines
Deal found 6/3![American Airlines logo]()
$147
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated June 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $215 (Kiwi.com) |
One-way from | $66 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $297 |
Good round-trip deal | $105 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaKansas City
OMA - MCI
OMAMCI
Omaha Eppley Airfield
Tue 6/30
8:25 pm-8:47 am
1 stop12h 22m
Kansas City
Tue 7/7
1:45 pm-7:15 pm
1 stop5h 30m
$215
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/13
5:40 am-10:30 am
1 stop4h 50m
Lambert-St Louis
Mon 8/17
2:00 pm-9:15 pm
1 stop7h 15m
$255
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Tue 6/16
6:30 pm-11:13 pm
1 stop4h 43m
Kansas City
Sat 6/20
6:41 pm-10:51 pm
1 stop4h 10m
$309
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 8/5
5:56 pm-11:26 pm
1 stop5h 30m
Lambert-St Louis
Sun 8/9
6:20 am-10:18 am
1 stop3h 58m
$309
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Wed 8/5
6:10 am-2:30 pm
2 stops8h 20m
Lambert-St Louis
Thu 8/6
6:05 am-11:25 am
1 stop5h 20m
$313
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Mon 6/15
8:15 pm-7:23 pm
1 stop23h 08m
Lambert-St Louis
Mon 7/6
8:08 pm-7:15 pm
1 stop23h 07m
$323
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 6/26
7:09 pm-12:16 am
1 stop5h 07m
Lambert-St Louis
Sun 6/28
8:14 pm-12:35 am
1 stop4h 21m
$325
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 6/27
6:03 pm-10:04 pm
1 stop4h 01m
Lambert-St Louis
Sat 7/4
3:57 pm-9:08 pm
1 stop5h 11m
$325
WaterlooSt. Louis
ALO - STL
ALOSTL
Waterloo
Wed 7/1
5:00 am-8:32 pm
1 stop15h 32m
Lambert-St Louis
Tue 7/7
9:08 am-12:29 am
1 stop39h 21m
$329
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 6/27
6:55 pm-11:45 pm
1 stop4h 50m
Lambert-St Louis
Sat 7/4
10:15 am-7:20 pm
2 stops9h 05m
$330
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
OMA-STL
DSM-STL
CID-MCI
ALO-STL
DSM-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
OMA-STL
DSM-STL
CID-MCI
ALO-STL
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated June 4, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Overall
8.0
Entertainment
7.5
Food
7.0
Crew
8.6
Boarding
8.1
Comfort
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on June 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 2 airlines flying from Iowa to Missouri
Discover the top 2 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$344 | FlexibilityNo cancel fee | On-time71% |