$86+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:10 am -
1 stop4h 24m
Sat 10/35:47 pm -
1 stop5h 05m
Deal found 8/21![Delta logo]()
$177
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 pm -
1 stop5h 36m
Sat 9/265:47 pm -
1 stop5h 05m
Deal found 8/20![Delta logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop25h 17m
Fri 9/258:32 pm -
1 stop22h 02m
Deal found 8/21![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Wed 9/232:29 pm -
2 stops29h 28m
Deal found 8/21![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Wed 9/238:10 pm -
1 stop14h 34m
Deal found 8/21![Frontier logo]()
$238
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:07 pm -
1 stop4h 20m
Sat 10/35:18 pm -
1 stop6h 55m
Deal found 8/21![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Sat 9/268:10 pm -
1 stop14h 34m
Deal found 8/21![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:29 pm -
1 stop23h 48m
Thu 9/246:39 pm -
2 stops47h 55m
Deal found 8/20![Frontier logo]()
$250
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:02 am -
1 stop6h 14m
Fri 9/255:18 pm -
1 stop6h 55m
Deal found 8/20![American Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/298:41 pm -
1 stop16h 41m
Mon 11/22:17 pm -
1 stop5h 29m
Deal found 8/18![Frontier logo]()
$270
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:59 am -
1 stop5h 48m
Wed 9/236:15 am -
1 stop4h 02m
Deal found 8/21![Delta logo]()
$271
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:10 am -
1 stop4h 24m
Sun 10/46:15 am -
1 stop4h 01m
Deal found 8/21![Delta logo]()
$272
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 pm -
1 stop5h 36m
Sat 9/265:47 pm -
1 stop5h 05m
Deal found 8/20![Delta logo]()
$187
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/152:40 pm -
1 stop3h 15m
Wed 9/1610:15 am -
2 stops11h 45m
Deal found 8/19![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am -
1 stop4h 39m
Sun 9/206:15 am -
1 stop4h 07m
Deal found 8/18![United Airlines logo]()
$306
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:44 am -
1 stop5h 29m
Thu 9/105:44 am -
1 stop4h 07m
Deal found 8/22![American Airlines logo]()
$308
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/24:30 pm -
2 stops8h 05m
Mon 10/52:25 pm -
1 stop7h 30m
Deal found 8/22![Southwest logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:01 pm -
1 stop20h 24m
Mon 9/79:12 pm -
2 stops45h 22m
Deal found 8/18![Multiple Airlines logo]()
$573
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:05 pm -
1 stop5h 15m
Wed 11/116:14 am -
1 stop3h 58m
Deal found 8/20![Delta logo]()
$289
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/262:15 pm -
Nonstop1h 20m
Tue 9/298:50 pm -
Nonstop1h 20m
Deal found 8/19![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:00 am -
1 stop6h 02m
Sun 9/66:00 am -
1 stop6h 20m
Deal found 8/18![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:10 am -
1 stop6h 44m
Tue 9/88:07 pm -
1 stop4h 13m
Deal found 8/23![American Airlines logo]()
$323
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:10 am -
1 stop4h 21m
Mon 9/215:47 pm -
1 stop5h 05m
Deal found 8/21![Delta logo]()
$297
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/125:55 pm -
Nonstop1h 15m
Sat 11/144:20 pm -
1 stop3h 25m
Deal found 8/21![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:21 pm -
1 stop5h 55m
Sun 9/68:00 am -
1 stop4h 20m
Deal found 8/18![United Airlines logo]()
$323
This American Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:48 pm -
1 stop5h 47m
Mon 9/77:39 pm -
1 stop4h 39m
Deal found 8/22![American Airlines logo]()
$329
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/207:00 am -
1 stop3h 31m
Thu 9/246:15 am -
1 stop4h 02m
Deal found 8/21![Delta logo]()
$315
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:40 pm -
Nonstop1h 15m
Sat 9/262:25 pm -
Nonstop1h 15m
Deal found 8/20![Southwest logo]()
$287
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:55 pm -
1 stop4h 04m
Thu 10/16:00 am -
1 stop4h 31m
Deal found 8/19![United Airlines logo]()
$341
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:50 am -
1 stop4h 36m
Mon 9/76:28 am -
1 stop4h 52m
Deal found 8/19![Delta logo]()
$319
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/128:15 am -
Nonstop1h 20m
Fri 11/135:10 am -
1 stop5h 10m
Deal found 8/23![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:22 pm -
1 stop16h 56m
Fri 9/2511:01 am -
1 stop13h 19m
Deal found 8/19![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:55 am -
1 stop6h 34m
Wed 2/105:00 am -
1 stop5h 33m
Deal found 8/19![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:20 pm -
1 stop4h 25m
Sat 10/31:45 pm -
Nonstop1h 15m
Deal found 8/21![Southwest logo]()
$292
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/304:30 pm -
1 stop7h 07m
Mon 2/15:00 pm -
1 stop4h 14m
Deal found 8/18![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/712:25 pm -
1 stop7h 40m
Sat 10/101:45 pm -
Nonstop1h 15m
Deal found 8/18![Southwest logo]()
$297
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/46:48 pm -
1 stop5h 47m
Mon 9/77:39 pm -
1 stop4h 39m
Deal found 8/23![American Airlines logo]()
$419
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop5h 26m
Wed 12/911:25 am -
1 stop5h 54m
Deal found 8/22![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/171:10 pm -
1 stop5h 55m
Thu 9/248:30 am -
Nonstop1h 15m
Deal found 8/20![Southwest logo]()
$302
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/307:55 am -
1 stop6h 24m
Tue 2/26:35 am -
1 stop7h 35m
Deal found 8/19![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/233:16 pm -
1 stop5h 30m
Thu 9/246:32 pm -
1 stop5h 41m
Deal found 8/18![American Airlines logo]()
$456
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:40 am -
1 stop4h 50m
Thu 9/173:15 pm -
2 stops7h 00m
Deal found 8/19![Southwest logo]()
$314
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated August 23, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:05 am -
1 stop5h 20m
Thu 9/103:45 pm -
2 stops6h 30m
Deal found 8/21![Southwest logo]()
$276
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:59 am -
1 stop5h 48m
Wed 9/236:15 am -
1 stop4h 02m
Deal found 8/21![Delta logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:29 pm -
1 stop23h 48m
Thu 9/246:39 pm -
2 stops47h 55m
Deal found 8/20![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop25h 17m
Fri 9/258:32 pm -
1 stop22h 02m
Deal found 8/21![Frontier logo]()
$196
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Wed 9/232:29 pm -
2 stops29h 28m
Deal found 8/21![Multiple Airlines logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Wed 9/238:10 pm -
1 stop14h 34m
Deal found 8/21![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Sat 9/268:10 pm -
1 stop14h 34m
Deal found 8/21![Frontier logo]()
$249
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:30 pm -
1 stop22h 47m
Mon 9/288:10 pm -
2 stops41h 42m
Deal found 8/21![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/201:58 pm -
2 stops23h 12m
Sat 9/268:10 pm -
1 stop14h 34m
Deal found 8/21![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/218:30 pm -
2 stops40h 40m
Sat 9/268:10 pm -
1 stop14h 34m
Deal found 8/21![Frontier logo]()
$275
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/225:40 pm -
1 stop5h 36m
Sat 9/265:47 pm -
1 stop5h 05m
Deal found 8/20![Delta logo]()
$187
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:02 am -
1 stop6h 14m
Fri 9/255:18 pm -
1 stop6h 55m
Deal found 8/20![American Airlines logo]()
$252
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:29 pm -
1 stop23h 48m
Deal found 8/23![Frontier logo]()
$86
This Delta deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:10 am -
1 stop4h 24m
Deal found 8/21![Delta logo]()
$89
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:07 pm -
1 stop4h 20m
Deal found 8/23![American Airlines logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop24h 57m
Deal found 8/21![Frontier logo]()
$97
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:10 am -
1 stop4h 21m
Deal found 8/20![Delta logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:59 pm -
1 stop21h 58m
Deal found 8/19![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:59 pm -
1 stop21h 58m
Deal found 8/20![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:29 pm -
2 stops41h 41m
Deal found 8/23![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/177:29 pm -
1 stop23h 48m
Deal found 8/18![Frontier logo]()
$113
This Faresmojo deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Faresmojo is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:55 am -
1 stop3h 43m
Deal found 8/18![JetBlue logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/167:29 pm -
2 stops20h 55m
Deal found 8/19![Frontier logo]()
$119
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/153:22 pm -
1 stop6h 38m
Deal found 8/18![United Airlines logo]()
$136
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated August 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $177 (Delta) |
One-way from | $86 (Kiwi.com) |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Tue 9/22
5:40 pm-11:16 pm
1 stop5h 36m
Lambert-St Louis
Sat 9/26
5:47 pm-10:52 pm
1 stop5h 05m
$187
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Tue 9/15
2:40 pm-5:55 pm
1 stop3h 15m
Lambert-St Louis
Wed 9/16
10:15 am-10:00 pm
2 stops11h 45m
$276
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Fri 10/2
4:30 pm-12:35 am
2 stops8h 05m
Lambert-St Louis
Mon 10/5
2:25 pm-9:55 pm
1 stop7h 30m
$285
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Sat 9/26
2:15 pm-3:35 pm
Nonstop1h 20m
Lambert-St Louis
Tue 9/29
8:50 pm-10:10 pm
Nonstop1h 20m
$287
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Thu 11/12
5:55 pm-7:10 pm
Nonstop1h 15m
Lambert-St Louis
Sat 11/14
4:20 pm-7:45 pm
1 stop3h 25m
$287
Quickest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Tue 9/22
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Sat 9/26
2:25 pm-3:40 pm
Nonstop1h 15m
$287
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Sat 11/7
5:05 pm-10:20 pm
1 stop5h 15m
Kansas City
Wed 11/11
6:14 am-10:12 am
1 stop3h 58m
$289
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Thu 11/12
8:15 am-9:35 am
Nonstop1h 20m
Lambert-St Louis
Fri 11/13
5:10 am-10:20 am
1 stop5h 10m
$292
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Fri 10/2
7:20 pm-11:45 pm
1 stop4h 25m
Lambert-St Louis
Sat 10/3
1:45 pm-3:00 pm
Nonstop1h 15m
$292
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Fri 9/18
6:10 am-10:31 am
1 stop4h 21m
Lambert-St Louis
Mon 9/21
5:47 pm-10:52 pm
1 stop5h 05m
$297
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
OMA-STL
DSM-STL
LSE-MCI
OMA-MCI
OMA-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
OMA-STL
DSM-STL
LSE-MCI
OMA-MCI
How much does it cost to fly round-trip from Iowa to Missouri?
Airfare is below average for this route at the moment.
Iowa to Missouri flights typically cost between $323 and $572 in September.The cheapest round-trip price found within the last 5 days was $229 on Multiple Airlines (Sep 18-Sep 23).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 23, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Entertainment
7.5
Overall
8.0
Boarding
8.1
Crew
8.6
Comfort
8.0
Food
7.0
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on August 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 2 airlines flying from Iowa to Missouri
Discover the top 2 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$261 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% |