Missouri

$39+ Cheap flights from Iowa to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/10. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Aug 16 — Aug 231
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Cheap flight deals from Iowa to Missouri

Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated August 11, 2025.

Round-trip from

$159
(American Airlines)

One-way from

$39
(Southwest)

Popular in

March

Cheapest in

September

Good round-trip deal

$105 or less

Good one-way deal

$180 or less
From Iowa to Missouri
One-way flight from Iowa to Missouri
Highest demand for flights based on searches. 23% potential increase in price ($116 potential increase over avg. RT price).
Cheapest flight prices on average. 18% potential price decrease ($59 potential savings vs. average RT price).
Price to beat on a round-trip flight from Iowa to Missouri.
Price to beat on a one-way flight from Iowa to Missouri.

Find flight deals from Iowa to Missouri

Cheapest flights from Iowa to Missouri
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 11, 2025.

This Southwest deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/183:50 pmDSM - STL
Nonstop1h 10mSouthwest
Sun 10/1910:15 amSTL - DSM
Nonstop1h 10mSouthwest
Deal found 8/11$114
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/44:20 pmDSM - STL
1 stop4h 12mAmerican Airlines
Sat 9/63:59 pmSTL - DSM
1 stop7h 14mAmerican Airlines
Deal found 8/9$159
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/225:15 pmOMA - STL
Nonstop1h 25mSouthwest
Mon 9/229:40 pmSTL - OMA
Nonstop1h 15mSouthwest
Deal found 8/9$177
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/255:44 amDSM - STL
1 stop6h 47mDelta
Thu 10/21:26 pmSTL - DSM
1 stop4h 19mDelta
Deal found 8/11$177
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/164:30 pmOMA - STL
Nonstop1h 15mSouthwest
Sat 9/202:05 pmSTL - OMA
2 stops6h 40mSouthwest
Deal found 8/9$181
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/208:05 amOMA - STL
1 stop3h 25mDelta
Sat 9/205:05 pmSTL - OMA
1 stop5h 39mDelta
Deal found 8/8$187
This Southwest deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/98:25 amDSM - MCI
1 stop3h 05mSouthwest
Wed 9/174:45 pmMCI - DSM
1 stop5h 35mSouthwest
Deal found 8/9$197
This Southwest deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/96:30 amDSM - MCI
2 stops7h 55mSouthwest
Tue 9/163:15 pmMCI - DSM
2 stops7h 05mSouthwest
Deal found 8/10$207
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/107:00 amDSM - STL
2 stops6h 20mDelta
Fri 9/125:11 pmSTL - DSM
1 stop5h 26mDelta
Deal found 8/11$218
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/912:10 pmCID - MCI
1 stop4h 36mDelta
Sat 9/1310:19 amMCI - CID
1 stop5h 15mDelta
Deal found 8/10$219
This FlightHub deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/58:35 pmOMA - STL
1 stop12h 31mFrontier
Sun 9/77:55 pmSTL - OMA
1 stop17h 26mFrontier
Deal found 8/9$224
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/237:00 amCID - MCI
1 stop4h 31mDelta
Tue 8/265:33 pmMCI - CID
1 stop5h 14mDelta
Deal found 8/9$229

Cheapflights Fare Finder

 
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.

Fly from

Iowa

Fly to

Missouri

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Sat 10/18

3:50 pm-5:00 pm

Nonstop1h 10m

Lambert-St Louis

Sun 10/19

10:15 am-11:25 am

Nonstop1h 10m

$114

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 9/4

4:20 pm-8:32 pm

1 stop4h 12m

Lambert-St Louis

Sat 9/6

3:59 pm-11:13 pm

1 stop7h 14m

$159

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Thu 9/25

5:44 am-12:31 pm

1 stop6h 47m

Lambert-St Louis

Thu 10/2

1:26 pm-5:45 pm

1 stop4h 19m

$177

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Mon 9/22

5:15 pm-6:40 pm

Nonstop1h 25m

Lambert-St Louis

Mon 9/22

9:40 pm-10:55 pm

Nonstop1h 15m

$177

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Tue 9/16

4:30 pm-5:45 pm

Nonstop1h 15m

Lambert-St Louis

Sat 9/20

2:05 pm-8:45 pm

2 stops6h 40m

$181

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Sat 9/20

8:05 am-11:30 am

1 stop3h 25m

Lambert-St Louis

Sat 9/20

5:05 pm-10:44 pm

1 stop5h 39m

$187

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Tue 9/9

8:25 am-11:30 am

1 stop3h 05m

Kansas City

Wed 9/17

4:45 pm-10:20 pm

1 stop5h 35m

$197

Des MoinesKansas City

DSM - MCI

DSMMCI

Des Moines

Tue 9/9

6:30 am-2:25 pm

2 stops7h 55m

Kansas City

Tue 9/16

3:15 pm-10:20 pm

2 stops7h 05m

$207

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Wed 9/10

7:00 am-1:20 pm

2 stops6h 20m

Lambert-St Louis

Fri 9/12

5:11 pm-10:37 pm

1 stop5h 26m

$218

Cedar RapidsKansas City

CID - MCI

CIDMCI

Cedar Rapids

Tue 9/9

12:10 pm-4:46 pm

1 stop4h 36m

Kansas City

Sat 9/13

10:19 am-3:34 pm

1 stop5h 15m

$219

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/10

Showing 1-10 of 59 results
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Best time to book a flight from Iowa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Missouri

What is the cheapest month to book a flight from Iowa to Missouri?

Currently, August is the cheapest month in which you can book a flight from Iowa to Missouri (average of $311). Flying from Iowa to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MO?

Find hourly flight availability from Iowa to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 11, 2025.

When flying from Iowa to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Reviews of airlines servicing Missouri

Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 11, 2025.
Peruse reviews from past customers who have flown with Southwest, Delta, and United Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.
8.0
Very good

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Food

7.0

Overall

8.0

Crew

8.6

Entertainment

7.5

Boarding

8.1

Comfort

8.0

Reviews

1 / 20
8.0
Excellent

Gina,Jul 2025

LAS - DEN

We experienced bad weather, which turned our 1.5 hour flight from Las Vegas to Denver, into 3.5. The pilot and crew kept us updated and explained that we had to circle and or possibly redirect to another airport. After circling for sometime, we were able to land smoothly in Denver. Thank you to all the flight crew, tower control, and all who got us to our destination safely.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How popular is this Iowa to Missouri flight route?

  • What are the cheapest airlines to fly from Iowa to Missouri one-way?

    One-way options have recently been found by users for as low as $39 on Southwest. Other airlines that offer cheap prices include United Airlines from $88 and Delta from $89 one-way.

  • Can I find deals for flights from Iowa to Missouri that include hotel bookings?

    Yes. In addition to deals on Iowa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Iowa to Missouri?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Missouri.

  • Can I find deals for business class flights from Iowa to Missouri?

    Yes. Cheapflights offers flight deals from Iowa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Iowa to Missouri?

    Currently, August is the cheapest month in which you can book a flight from Iowa to Missouri (average of $311). Flying from Iowa to Missouri in March is currently the most expensive (average of $356). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Iowa to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Iowa to Missouri

Discover the top 4 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
Southern / MokuleleCheapest$61Average$85FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$97Average$308FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$198Average$383FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$218Average$296FlexibilityNo cancel feeOn-time71%

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