$105+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/9. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — MCI
Aug 3 — Aug 101
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 4, 2026.
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:55 am
DSM
- STL
1 stop3h 28m
Delta
Sat 8/226:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 7/2![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- STL
2 stops9h 30m
Southwest
Tue 8/43:45 pm
STL
- DSM
1 stop6h 10m
Southwest
Deal found 6/30![Southwest logo]()
$214
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:55 am
DSM
- STL
1 stop3h 28m
Delta
Thu 8/206:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 6/29![Delta logo]()
$215
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
DSM
- STL
1 stop6h 40m
United Airlines
Sat 9/57:25 am
STL
- DSM
1 stop6h 51m
United Airlines
Deal found 7/3![United Airlines logo]()
$222
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:10 pm
DSM
- STL
2 stops7h 35m
Southwest
Sat 8/228:30 am
STL
- DSM
2 stops10h 55m
Southwest
Deal found 6/30![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
DSM
- STL
2 stops12h 45m
Southwest
Sat 9/58:25 am
STL
- DSM
1 stop3h 05m
Southwest
Deal found 7/3![Southwest logo]()
$227
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- STL
2 stops9h 40m
Southwest
Thu 10/15:40 am
STL
- DSM
1 stop5h 40m
Southwest
Deal found 6/29![Southwest logo]()
$230
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Thu 8/206:00 am
STL
- DSM
1 stop3h 56m
American Airlines
Deal found 6/30![American Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Mon 8/243:15 pm
STL
- DSM
2 stops6h 55m
Southwest
Deal found 7/3![Southwest logo]()
$240
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Fri 8/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 7/2![Frontier logo]()
$243
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Thu 8/2010:10 am
STL
- DSM
2 stops12h 00m
Southwest
Deal found 6/30![Southwest logo]()
$246
This Booking.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:24 pm
CID
- MCI
1 stop16h 36m
Frontier
Wed 8/121:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 7/3![Frontier logo]()
$258
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 4, 2026.
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:10 pm
DSM
- STL
2 stops7h 35m
Southwest
Sat 8/228:55 am
STL
- DSM
1 stop5h 15m
Southwest
Deal found 6/30![Southwest logo]()
$214
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:55 am
DSM
- STL
1 stop3h 28m
Delta
Thu 8/206:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 6/29![Delta logo]()
$215
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
DSM
- STL
1 stop6h 40m
United Airlines
Sat 9/57:25 am
STL
- DSM
1 stop6h 51m
United Airlines
Deal found 7/3![United Airlines logo]()
$222
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:48 pm
CID
- MCI
1 stop5h 47m
American Airlines
Sat 8/157:39 pm
MCI
- CID
1 stop4h 39m
American Airlines
Deal found 7/1![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:55 am
DSM
- STL
1 stop3h 28m
Delta
Sat 8/226:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 7/3![Delta logo]()
$235
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
DSM
- STL
2 stops12h 45m
Southwest
Sat 9/58:30 am
STL
- DSM
2 stops10h 55m
Southwest
Deal found 7/3![Southwest logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/179:28 am
CID
- MCI
1 stop7h 22m
Multiple Airlines
Wed 8/1911:26 am
MCI
- CID
2 stops26h 17m
Multiple Airlines
Deal found 6/29![Multiple Airlines logo]()
$500
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:09 pm
OMA
- STL
1 stop6h 51m
United Airlines
Tue 8/188:00 am
STL
- OMA
1 stop6h 04m
United Airlines
Deal found 6/29![United Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Mon 8/243:15 pm
STL
- DSM
2 stops6h 55m
Southwest
Deal found 7/3![Southwest logo]()
$240
This American Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:48 pm
CID
- MCI
1 stop5h 47m
American Airlines
Sun 8/97:39 pm
MCI
- CID
1 stop4h 39m
American Airlines
Deal found 7/4![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Thu 8/2010:10 am
STL
- DSM
2 stops12h 00m
Southwest
Deal found 6/30![Southwest logo]()
$246
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/226:29 am
DSM
- STL
1 stop5h 28m
United Airlines
Wed 9/2312:59 pm
STL
- DSM
1 stop4h 29m
United Airlines
Deal found 7/2![United Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- STL
2 stops9h 40m
Southwest
Thu 10/110:15 am
STL
- DSM
2 stops13h 15m
Southwest
Deal found 6/29![Southwest logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1712:06 pm
OMA
- SGF
2 stops29h 23m
Allegiant Air
Tue 7/2110:41 am
SGF
- OMA
1 stop23h 14m
Allegiant Air
Deal found 7/2![Allegiant Air logo]()
$697
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:48 pm
OMA
- SGF
1 stop6h 55m
United Airlines
Sat 8/151:37 pm
SGF
- OMA
1 stop6h 27m
United Airlines
Deal found 7/2![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:53 am
OMA
- COU
1 stop6h 56m
American Airlines
Mon 7/206:32 pm
COU
- OMA
1 stop6h 05m
American Airlines
Deal found 7/1![American Airlines logo]()
$323
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:40 pm
OMA
- SGF
1 stop4h 47m
United Airlines
Thu 8/1311:20 am
SGF
- OMA
1 stop6h 57m
United Airlines
Deal found 7/3![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/84:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 9/98:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/1![Southwest logo]()
$275
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/145:20 am
OMA
- SGF
1 stop6h 56m
American Airlines
Sat 7/187:53 pm
SGF
- OMA
1 stop4h 13m
American Airlines
Deal found 6/29![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:55 am
OMA
- SGF
1 stop6h 37m
United Airlines
Wed 8/56:34 pm
SGF
- OMA
1 stop4h 40m
United Airlines
Deal found 7/1![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Tue 8/188:35 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/29![Southwest logo]()
$285
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:35 pm
OMA
- COU
1 stop4h 20m
United Airlines
Tue 9/19:00 am
COU
- OMA
1 stop7h 28m
United Airlines
Deal found 6/30![United Airlines logo]()
$338
This Kiwi.com deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/169:48 am
OMA
- SGF
1 stop23h 42m
Multiple Airlines
Mon 7/201:21 pm
SGF
- OMA
2 stops29h 54m
Multiple Airlines
Deal found 6/30![Multiple Airlines logo]()
$548
This Southwest deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Fri 8/78:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/2![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/73:13 pm
OMA
- STL
1 stop6h 13m
United Airlines
Mon 8/107:05 pm
STL
- OMA
1 stop4h 09m
United Airlines
Deal found 6/30![United Airlines logo]()
$340
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/176:48 pm
CID
- MCI
1 stop5h 47m
American Airlines
Wed 8/197:39 pm
MCI
- CID
1 stop4h 39m
American Airlines
Deal found 6/29![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/35:15 pm
OMA
- STL
Nonstop1h 15m
Southwest
Wed 8/58:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 7/1![Southwest logo]()
$333
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/83:14 pm
CID
- MCI
1 stop5h 38m
United Airlines
Sat 12/121:45 pm
MCI
- CID
1 stop6h 35m
United Airlines
Deal found 6/29![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/185:41 pm
LSE
- MCI
1 stop6h 38m
American Airlines
Tue 7/217:46 pm
MCI
- LSE
1 stop4h 13m
American Airlines
Deal found 6/30![American Airlines logo]()
$498
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Thu 7/239:45 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 7/1![Southwest logo]()
$344
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated July 4, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated July 4, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/285:20 am
DSM
- STL
2 stops9h 30m
Southwest
Tue 8/43:45 pm
STL
- DSM
1 stop6h 10m
Southwest
Deal found 6/30![Southwest logo]()
$214
This Booking.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Fri 8/78:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 7/2![Frontier logo]()
$243
This Booking.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/88:24 pm
CID
- MCI
1 stop16h 36m
Frontier
Wed 8/121:45 pm
MCI
- CID
1 stop24h 21m
Frontier
Deal found 7/3![Frontier logo]()
$258
This Delta deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/136:55 am
DSM
- STL
1 stop3h 28m
Delta
Thu 8/206:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 6/29![Delta logo]()
$215
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/137:49 pm
DSM
- STL
1 stop4h 25m
American Airlines
Thu 8/206:00 am
STL
- DSM
1 stop3h 56m
American Airlines
Deal found 6/30![American Airlines logo]()
$235
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Thu 8/2010:10 am
STL
- DSM
2 stops12h 00m
Southwest
Deal found 6/30![Southwest logo]()
$246
This Delta deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:55 am
DSM
- STL
1 stop3h 28m
Delta
Sat 8/226:20 am
STL
- DSM
1 stop3h 58m
Delta
Deal found 7/2![Delta logo]()
$209
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:10 pm
DSM
- STL
2 stops7h 35m
Southwest
Sat 8/228:30 am
STL
- DSM
2 stops10h 55m
Southwest
Deal found 6/30![Southwest logo]()
$225
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/173:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Mon 8/243:15 pm
STL
- DSM
2 stops6h 55m
Southwest
Deal found 7/3![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- STL
2 stops9h 40m
Southwest
Thu 10/15:40 am
STL
- DSM
1 stop5h 40m
Southwest
Deal found 6/29![Southwest logo]()
$230
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/273:20 pm
DSM
- STL
1 stop6h 40m
United Airlines
Sat 9/57:25 am
STL
- DSM
1 stop6h 51m
United Airlines
Deal found 7/3![United Airlines logo]()
$222
This Southwest deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/275:40 am
DSM
- STL
2 stops12h 45m
Southwest
Sat 9/58:25 am
STL
- DSM
1 stop3h 05m
Southwest
Deal found 7/3![Southwest logo]()
$227
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated July 4, 2026.
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/296:33 pm
DSM
- STL
1 stop5h 43m
American Airlines
Deal found 6/30![American Airlines logo]()
$105
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:20 am
DSM
- STL
2 stops9h 30m
Southwest
Deal found 6/30![Southwest logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3110:36 pm
OMA
- STL
1 stop19h 14m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$116
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/153:20 pm
DSM
- STL
1 stop6h 40m
United Airlines
Deal found 7/3![United Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/289:33 pm
OMA
- STL
1 stop14h 18m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$123
This Southwest deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:40 am
DSM
- STL
2 stops9h 40m
Southwest
Deal found 6/30![Southwest logo]()
$123
This Frontier deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/212:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 6/30![Frontier logo]()
$126
This United Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/78:00 am
OMA
- STL
1 stop4h 13m
United Airlines
Deal found 6/29![United Airlines logo]()
$131
This Frontier deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/302:18 pm
OMA
- STL
1 stop4h 55m
Frontier
Deal found 6/30![Frontier logo]()
$135
This Southwest deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 7/1![Southwest logo]()
$138
This Delta deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2910:56 am
OMA
- STL
1 stop5h 51m
Delta
Deal found 7/3![Delta logo]()
$143
This Kiwi.com deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/1512:26 pm
DSM
- STL
2 stops44h 31m
Multiple Airlines
Deal found 7/3![Multiple Airlines logo]()
$143
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated July 4, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $209 (Delta) |
One-way from | $105 (American Airlines) |
Popular in | July |
Cheapest in | May |
Average price | $663 |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 8/15
12:10 pm-7:45 pm
2 stops7h 35m
Lambert-St Louis
Sat 8/22
8:55 am-2:10 pm
1 stop5h 15m
$214
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/13
6:55 am-10:23 am
1 stop3h 28m
Lambert-St Louis
Thu 8/20
6:20 am-10:18 am
1 stop3h 58m
$215
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/27
3:20 pm-10:00 pm
1 stop6h 40m
Lambert-St Louis
Sat 9/5
7:25 am-2:16 pm
1 stop6h 51m
$222
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Sat 8/15
6:55 am-10:23 am
1 stop3h 28m
Lambert-St Louis
Sat 8/22
6:20 am-10:18 am
1 stop3h 58m
$235
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/27
5:40 am-6:25 pm
2 stops12h 45m
Lambert-St Louis
Sat 9/5
8:30 am-7:25 pm
2 stops10h 55m
$238
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Mon 8/17
3:50 pm-10:05 pm
1 stop6h 15m
Lambert-St Louis
Mon 8/24
3:15 pm-10:10 pm
2 stops6h 55m
$240
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/13
3:50 pm-10:05 pm
1 stop6h 15m
Lambert-St Louis
Thu 8/20
10:10 am-10:10 pm
2 stops12h 00m
$246
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 8/20
5:40 am-3:20 pm
2 stops9h 40m
Lambert-St Louis
Thu 10/1
10:15 am-11:30 pm
2 stops13h 15m
$251
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Mon 8/17
3:09 pm-10:00 pm
1 stop6h 51m
Lambert-St Louis
Tue 8/18
8:00 am-2:04 pm
1 stop6h 04m
$261
Quickest round-trip
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Tue 9/8
4:40 pm-5:55 pm
Nonstop1h 15m
Lambert-St Louis
Wed 9/9
8:50 pm-10:05 pm
Nonstop1h 15m
$275
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
CID-MCI
OMA-STL
OMA-SGF
OMA-COU
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
CID-MCI
OMA-STL
OMA-SGF
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated July 4, 2026.
Peruse reviews from past customers who have flown with Southwest and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Food
7.0
Boarding
8.1
Entertainment
7.5
Comfort
8.0
Overall
7.9
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on July 4, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 2 airlines flying from Iowa to Missouri
Discover the top 2 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$344 | FlexibilityNo cancel fee | On-time71% |