$66+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/8. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Thg. 5 10 — Thg. 5 171
Round-trip
1 adult, Economy
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Tháng Tư 10, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Tháng Tư 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 3 5/268:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 3 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/5![Frontier logo]()
$198
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
CN 5/38:06 pm
STL
- DSM
1 stop23h 32m
Frontier
Deal found 4/6![Frontier logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/88:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 7 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/7![Frontier logo]()
$256
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/64:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/138:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/288:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 4 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/8![Frontier logo]()
$258
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/162:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/208:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/5![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 4/292:05 pm
OMA
- STL
1 stop7h 40m
Southwest
Th. 4 5/68:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/26:50 am
OMA
- STL
Nonstop1h 15m
Southwest
Th. 2 5/49:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/65:30 am
DSM
- STL
1 stop4h 00m
Southwest
Th. 4 5/133:55 pm
STL
- DSM
1 stop6h 15m
Southwest
Deal found 4/6![Southwest logo]()
$279
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/165:35 am
DSM
- STL
1 stop4h 55m
Southwest
Th. 4 5/205:35 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 4/8![Southwest logo]()
$288
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 4/202:04 pm
DSM
- STL
1 stop5h 28m
Frontier
Th. 5 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Deal found 4/6![Frontier logo]()
$291
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/44:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Th. 2 5/114:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$297
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Tháng Tư 10, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Tháng Tư 10, 2026.
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/64:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/138:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/110:21 am
OMA
- STL
2 stops20h 29m
Multiple Airlines
Th. 7 5/28:17 pm
STL
- OMA
1 stop23h 56m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$293
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 4/235:17 am
OMA
- COU
1 stop6h 18m
American Airlines
Th. 2 4/275:21 pm
COU
- OMA
1 stop6h 11m
American Airlines
Deal found 4/8![American Airlines logo]()
$298
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
CN 5/318:15 pm
DSM
- STL
1 stop4h 04m
United Airlines
Th. 4 6/106:00 am
STL
- DSM
1 stop4h 27m
United Airlines
Deal found 4/5![United Airlines logo]()
$298
This Delta deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 4/246:31 pm
DSM
- STL
1 stop5h 05m
Delta
CN 4/266:20 am
STL
- DSM
1 stop3h 56m
Delta
Deal found 4/5![Delta logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
CN 5/318:19 pm
OMA
- MCI
1 stop17h 30m
Frontier
Th. 4 6/36:24 pm
MCI
- OMA
2 stops25h 10m
Frontier
Deal found 4/9![Frontier logo]()
$447
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/162:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/208:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/5![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/285:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 6/38:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$263
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/86:41 pm
CID
- MCI
1 stop4h 50m
United Airlines
Th. 6 5/156:17 am
MCI
- CID
1 stop4h 10m
United Airlines
Deal found 4/9![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 4/305:17 am
OMA
- SGF
1 stop5h 07m
American Airlines
Th. 3 5/54:49 pm
SGF
- OMA
1 stop6h 43m
American Airlines
Deal found 4/6![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/26:50 am
OMA
- STL
Nonstop1h 15m
Southwest
Th. 7 5/210:35 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/5![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/77:06 pm
OMA
- MCI
1 stop20h 39m
Multiple Airlines
Th. 5 5/147:03 pm
MCI
- OMA
1 stop16h 41m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$353
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/22:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 2 5/47:20 am
STL
- OMA
1 stop6h 00m
Southwest
Deal found 4/6![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 4/244:02 pm
OMA
- SGF
1 stop6h 36m
American Airlines
Th. 3 4/2810:21 am
SGF
- OMA
1 stop5h 11m
American Airlines
Deal found 4/9![American Airlines logo]()
$339
This United Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 4/223:22 pm
OMA
- COU
1 stop6h 39m
United Airlines
CN 4/263:23 pm
COU
- OMA
1 stop6h 48m
United Airlines
Deal found 4/7![United Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/15:17 am
OMA
- SGF
1 stop5h 07m
American Airlines
Th. 6 5/86:09 pm
SGF
- OMA
1 stop5h 50m
American Airlines
Deal found 4/6![American Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/214:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Th. 5 5/285:40 am
STL
- DSM
1 stop6h 05m
Southwest
Deal found 4/6![Southwest logo]()
$297
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/16:41 pm
CID
- MCI
1 stop4h 50m
United Airlines
CN 5/36:17 am
MCI
- CID
1 stop4h 10m
United Airlines
Deal found 4/5![United Airlines logo]()
$369
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 7/185:35 pm
LSE
- MCI
1 stop6h 42m
American Airlines
Th. 3 7/217:46 pm
MCI
- LSE
1 stop4h 13m
American Airlines
Deal found 4/7![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/96:30 am
CID
- MCI
1 stop4h 03m
United Airlines
Th. 4 5/136:17 am
MCI
- CID
1 stop4h 09m
United Airlines
Deal found 4/9![United Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 6/196:04 pm
CID
- MCI
2 stops23h 20m
Multiple Airlines
Th. 6 7/317:37 pm
MCI
- CID
1 stop13h 18m
Multiple Airlines
Deal found 4/8![Multiple Airlines logo]()
$460
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/25:35 am
DSM
- STL
2 stops8h 00m
Southwest
CN 5/35:25 am
STL
- DSM
1 stop6h 00m
Southwest
Deal found 4/5![Southwest logo]()
$316
This American Airlines deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/206:36 pm
LSE
- MCI
1 stop5h 40m
American Airlines
Th. 2 5/257:42 pm
MCI
- LSE
1 stop4h 24m
American Airlines
Deal found 4/8![American Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 4/254:46 pm
CID
- MCI
1 stop6h 46m
United Airlines
Th. 3 4/281:54 pm
MCI
- CID
1 stop7h 06m
United Airlines
Deal found 4/5![United Airlines logo]()
$374
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 7/46:10 am
DSM
- STL
1 stop7h 20m
Southwest
Th. 2 7/66:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 4/6![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 4/306:37 pm
LSE
- MCI
1 stop4h 20m
American Airlines
CN 5/35:33 am
MCI
- LSE
1 stop4h 02m
American Airlines
Deal found 4/7![American Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/1112:52 pm
CID
- MCI
2 stops24h 57m
Multiple Airlines
Th. 4 5/132:34 pm
MCI
- CID
1 stop22h 32m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$494
This United Airlines deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/16:53 pm
OMA
- SGF
1 stop5h 54m
United Airlines
Th. 6 5/86:22 pm
SGF
- OMA
1 stop5h 09m
United Airlines
Deal found 4/9![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
CN 6/146:10 pm
DSM
- STL
1 stop5h 45m
Southwest
Th. 6 6/196:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Deal found 4/9![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/210:05 am
LSE
- STL
1 stop13h 41m
American Airlines
Th. 3 5/512:27 pm
STL
- LSE
1 stop21h 08m
American Airlines
Deal found 4/6![American Airlines logo]()
$371
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated Tháng Tư 10, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated Tháng Tư 10, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 4/202:04 pm
DSM
- STL
1 stop5h 28m
Frontier
Th. 5 4/238:06 pm
STL
- DSM
1 stop17h 03m
Frontier
Deal found 4/6![Frontier logo]()
$291
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 4/292:05 pm
OMA
- STL
1 stop7h 40m
Southwest
Th. 4 5/68:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$267
This Frontier deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
CN 5/38:06 pm
STL
- DSM
1 stop23h 32m
Frontier
Deal found 4/6![Frontier logo]()
$205
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/26:50 am
OMA
- STL
Nonstop1h 15m
Southwest
Th. 2 5/49:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/44:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Th. 2 5/114:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Deal found 4/6![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/64:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/138:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/8![Southwest logo]()
$257
This Southwest deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 5/65:30 am
DSM
- STL
1 stop4h 00m
Southwest
Th. 4 5/133:55 pm
STL
- DSM
1 stop6h 15m
Southwest
Deal found 4/6![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/88:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 7 5/98:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/7![Frontier logo]()
$256
This Southwest deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/162:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Th. 4 5/208:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 4/5![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 7 5/165:35 am
DSM
- STL
1 stop4h 55m
Southwest
Th. 4 5/205:35 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 4/8![Southwest logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 3 5/268:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 3 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/5![Frontier logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/288:19 pm
OMA
- STL
2 stops12h 36m
Frontier
Th. 4 6/38:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 4/8![Frontier logo]()
$258
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated Tháng Tư 10, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated Tháng Tư 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 6/87:56 pm
OMA
- STL
1 stop23h 27m
Frontier
Deal found 4/9![Frontier logo]()
$66
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 3 6/28:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/6![Frontier logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 6/18:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/5![Frontier logo]()
$79
This Frontier deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 4 6/32:16 pm
DSM
- STL
1 stop5h 07m
Frontier
Deal found 4/5![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 5 5/78:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/6![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 6 5/88:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 4/6![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 3 6/98:29 pm
OMA
- STL
1 stop22h 54m
Frontier
Deal found 4/8![Frontier logo]()
$104
This Frontier deal was found by Cheapflights users on 4/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 4/272:04 pm
DSM
- STL
1 stop5h 28m
Frontier
Deal found 4/9![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/118:19 pm
OMA
- STL
2 stops21h 14m
Frontier
Deal found 4/8![Frontier logo]()
$114
This eDestinos deal was found by Cheapflights users on 4/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure eDestinos is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/48:23 pm
DSM
- STL
2 stops36h 32m
Frontier
Deal found 4/8![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Th. 2 5/48:43 pm
OMA
- STL
2 stops45h 23m
Frontier
Deal found 4/6![Frontier logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 4/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
CN 5/32:36 pm
DSM
- STL
2 stops16h 14m
Multiple Airlines
Deal found 4/7![Multiple Airlines logo]()
$127
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated Tháng Tư 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $198 (Kiwi.com) |
One-way from | $66 (Kiwi.com) |
Popular in | July |
Cheapest in | September |
Average price | $299 |
Good round-trip deal | $105 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Tháng Tư 10, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 4 5/6
4:45 pm-6:00 pm
Nonstop1h 15m
Lambert-St Louis
Th. 4 5/13
8:50 pm-10:10 pm
Nonstop1h 20m
$257
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 7 5/16
2:50 pm-4:05 pm
Nonstop1h 15m
Lambert-St Louis
Th. 4 5/20
8:25 am-9:45 am
Nonstop1h 20m
$263
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 5 5/28
5:40 pm-6:55 pm
Nonstop1h 15m
Lambert-St Louis
Th. 4 6/3
8:25 am-9:45 am
Nonstop1h 20m
$263
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 7 5/2
6:50 am-8:05 am
Nonstop1h 15m
Lambert-St Louis
Th. 7 5/2
10:35 am-11:55 am
Nonstop1h 20m
$269
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 7 5/2
2:50 pm-4:05 pm
Nonstop1h 15m
Lambert-St Louis
Th. 2 5/4
7:20 am-1:20 pm
1 stop6h 00m
$279
OmahaSt. Louis
OMA - STL
OMASTL
Omaha Eppley Airfield
Th. 6 5/1
10:21 am-6:50 am
2 stops20h 29m
Lambert-St Louis
Th. 7 5/2
8:17 pm-8:13 pm
1 stop23h 56m
$293
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Th. 5 5/21
4:20 pm-10:45 pm
1 stop6h 25m
Lambert-St Louis
Th. 5 5/28
5:40 am-11:45 am
1 stop6h 05m
$297
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Th. 5 4/23
5:17 am-11:35 am
1 stop6h 18m
Columbia Regional
Th. 2 4/27
5:21 pm-11:32 pm
1 stop6h 11m
$298
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
CN 5/31
8:15 pm-12:19 am
1 stop4h 04m
Lambert-St Louis
Th. 4 6/10
6:00 am-10:27 am
1 stop4h 27m
$298
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Th. 6 5/8
6:41 pm-11:31 pm
1 stop4h 50m
Kansas City
Th. 6 5/15
6:17 am-10:27 am
1 stop4h 10m
$299
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
OMA-STL
OMA-COU
DSM-STL
OMA-MCI
CID-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
OMA-STL
OMA-COU
DSM-STL
OMA-MCI
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $93). Flying from Iowa to Missouri in January is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from Iowa to Missouri?
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated Tháng Tư 10, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Comfort
8.0
Entertainment
7.5
Overall
8.0
Boarding
8.1
Food
7.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on Tháng Tư 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Tháng Tư 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$253 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$418 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$297 | FlexibilityNo cancel fee | On-time71% |