$84+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/25. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Sep 28 — Oct 51
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 29, 2026.
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:02 am -
1 stop6h 14m
Wed 9/165:00 am -
1 stop6h 48m
Deal found 8/24![American Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:29 pm -
2 stops16h 03m
Fri 9/188:10 pm -
1 stop22h 24m
Deal found 8/24![Frontier logo]()
$220
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop4h 48m
Sat 10/106:00 am -
1 stop4h 24m
Deal found 8/24![United Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:02 am -
1 stop6h 14m
Wed 9/305:00 am -
1 stop4h 51m
Deal found 8/27![American Airlines logo]()
$247
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:27 pm -
1 stop14h 05m
Wed 9/168:10 pm -
1 stop22h 24m
Deal found 8/26![Multiple Airlines logo]()
$256
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:02 am -
1 stop6h 14m
Mon 9/217:21 am -
1 stop4h 27m
Deal found 8/26![American Airlines logo]()
$268
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm -
1 stop4h 35m
Tue 10/134:05 pm -
1 stop5h 50m
Deal found 8/26![Southwest logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:26 pm -
1 stop5h 17m
Sun 9/205:18 pm -
1 stop6h 55m
Deal found 8/24![American Airlines logo]()
$272
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm -
1 stop4h 35m
Thu 10/152:30 pm -
2 stops8h 25m
Deal found 8/24![Southwest logo]()
$276
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:55 pm -
Nonstop1h 10m
Sat 10/178:25 am -
Nonstop1h 15m
Deal found 8/27![Southwest logo]()
$277
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:35 pm -
1 stop4h 40m
Fri 10/95:25 am -
1 stop5h 45m
Deal found 8/27![Southwest logo]()
$280
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops9h 25m
Wed 10/282:20 pm -
2 stops7h 35m
Deal found 8/25![Southwest logo]()
$281
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 29, 2026.
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:00 am -
1 stop6h 14m
Sat 10/107:01 pm -
1 stop3h 58m
Deal found 8/25![United Airlines logo]()
$232
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm -
1 stop4h 35m
Tue 10/134:05 pm -
1 stop5h 50m
Deal found 8/26![Southwest logo]()
$271
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:34 pm -
1 stop3h 54m
Mon 10/127:21 pm -
1 stop4h 59m
Deal found 8/28![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1712:10 pm -
1 stop4h 44m
Tue 9/225:34 pm -
1 stop5h 25m
Deal found 8/28![Delta logo]()
$364
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:10 pm -
1 stop4h 35m
Thu 10/152:30 pm -
2 stops8h 25m
Deal found 8/24![Southwest logo]()
$276
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/235:32 pm -
1 stop6h 10m
Wed 9/306:25 pm -
1 stop4h 34m
Deal found 8/26![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:40 am -
1 stop4h 50m
Tue 9/292:50 pm -
2 stops6h 15m
Deal found 8/26![Southwest logo]()
$276
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/122:17 pm -
1 stop5h 06m
Wed 9/165:44 am -
1 stop4h 07m
Deal found 8/28![American Airlines logo]()
$308
This United Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:48 pm -
1 stop7h 13m
Mon 11/25:02 pm -
1 stop6h 09m
Deal found 8/24![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/102:55 pm -
Nonstop1h 10m
Sat 10/178:25 am -
Nonstop1h 15m
Deal found 8/24![Southwest logo]()
$277
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:33 pm -
1 stop3h 50m
Sat 9/125:13 am -
1 stop6h 07m
Deal found 8/24![American Airlines logo]()
$319
This United Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:25 am -
1 stop4h 00m
Mon 9/216:45 pm -
1 stop3h 57m
Deal found 8/28![United Airlines logo]()
$304
This Southwest deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:55 pm -
Nonstop1h 10m
Tue 10/138:50 pm -
Nonstop1h 15m
Deal found 8/23![Southwest logo]()
$277
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/275:35 am -
2 stops9h 20m
Thu 10/291:05 pm -
2 stops9h 50m
Deal found 8/25![Southwest logo]()
$281
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/116:30 am -
1 stop3h 55m
Sat 9/121:08 pm -
1 stop4h 37m
Deal found 8/27![United Airlines logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/185:22 pm -
1 stop16h 56m
Fri 9/2511:01 am -
1 stop13h 19m
Deal found 8/25![American Airlines logo]()
$361
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/811:32 am -
1 stop4h 12m
Sat 9/1212:59 pm -
1 stop4h 29m
Deal found 8/25![United Airlines logo]()
$323
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/32:55 pm -
Nonstop1h 10m
Mon 10/56:10 pm -
1 stop5h 25m
Deal found 8/28![Southwest logo]()
$297
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:50 am -
2 stops8h 05m
Wed 9/306:30 am -
1 stop5h 10m
Deal found 8/27![Southwest logo]()
$302
This American Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/45:57 am -
1 stop3h 51m
Sat 11/76:14 am -
1 stop5h 39m
Deal found 8/25![American Airlines logo]()
$408
This United Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/67:55 am -
1 stop6h 34m
Wed 2/105:00 am -
1 stop5h 33m
Deal found 8/26![United Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:33 pm -
1 stop3h 50m
Sun 9/207:35 pm -
1 stop4h 42m
Deal found 8/28![American Airlines logo]()
$411
This Southwest deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:40 pm -
Nonstop1h 15m
Sun 9/208:25 am -
Nonstop1h 15m
Deal found 8/24![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:00 am -
1 stop5h 26m
Wed 12/911:25 am -
1 stop5h 54m
Deal found 8/25![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:10 am -
1 stop3h 50m
Sun 10/185:45 am -
1 stop5h 35m
Deal found 8/26![Southwest logo]()
$315
This United Airlines deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:05 am -
1 stop4h 21m
Mon 10/56:39 pm -
1 stop4h 08m
Deal found 8/25![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/125:10 am -
1 stop3h 50m
Mon 10/195:25 am -
1 stop5h 45m
Deal found 8/28![Southwest logo]()
$319
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/1412:23 pm -
1 stop11h 35m
Sun 1/171:06 pm -
1 stop22h 47m
Deal found 8/26![American Airlines logo]()
$489
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/193:11 pm -
1 stop6h 51m
Tue 9/226:37 pm -
1 stop4h 32m
Deal found 8/27![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:10 am -
1 stop3h 25m
Sat 9/127:50 am -
2 stops11h 40m
Deal found 8/25![Southwest logo]()
$328
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated August 29, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated August 29, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/611:32 am -
1 stop5h 34m
Fri 9/118:00 am -
1 stop4h 16m
Deal found 8/27![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:05 am -
1 stop3h 50m
Fri 9/113:15 pm -
2 stops7h 00m
Deal found 8/27![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:29 pm -
2 stops16h 03m
Fri 9/188:10 pm -
1 stop22h 24m
Deal found 8/24![Frontier logo]()
$220
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:27 pm -
1 stop14h 05m
Wed 9/168:10 pm -
1 stop22h 24m
Deal found 8/26![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/149:27 pm -
1 stop14h 05m
Fri 9/188:10 pm -
1 stop22h 24m
Deal found 8/24![Multiple Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:02 am -
1 stop6h 14m
Wed 9/165:00 am -
1 stop6h 48m
Deal found 8/24![American Airlines logo]()
$177
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:26 pm -
1 stop5h 17m
Sun 9/205:18 pm -
1 stop6h 55m
Deal found 8/24![American Airlines logo]()
$272
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:02 am -
1 stop6h 14m
Mon 9/217:21 am -
1 stop4h 27m
Deal found 8/26![American Airlines logo]()
$268
This American Airlines deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/248:07 pm -
1 stop4h 20m
Sat 9/265:00 am -
1 stop4h 51m
Deal found 8/24![American Airlines logo]()
$232
This American Airlines deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/297:02 am -
1 stop6h 14m
Wed 9/305:00 am -
1 stop4h 51m
Deal found 8/27![American Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/294:40 pm -
Nonstop1h 15m
Wed 9/308:50 pm -
Nonstop1h 20m
Deal found 8/27![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:39 am -
1 stop4h 48m
Tue 10/65:20 pm -
1 stop5h 40m
Deal found 8/25![Delta logo]()
$289
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated August 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/257:29 pm -
1 stop23h 48m
Deal found 8/26![Frontier logo]()
$84
This American Airlines deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:07 pm -
1 stop4h 20m
Deal found 8/26![American Airlines logo]()
$89
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:20 pm -
1 stop24h 57m
Deal found 8/26![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/147:29 pm -
2 stops41h 41m
Deal found 8/24![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 8/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:59 pm -
1 stop21h 58m
Deal found 8/27![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:40 am -
2 stops30h 30m
Deal found 8/26![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/217:29 pm -
2 stops41h 41m
Deal found 8/24![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 8/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:59 pm -
1 stop22h 15m
Deal found 8/28![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:10 am -
2 stops29h 00m
Deal found 8/25![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 8/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/268:59 pm -
2 stops44h 41m
Deal found 8/24![Frontier logo]()
$115
This Kiwi.com deal was found by Cheapflights users on 8/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/218:22 pm -
2 stops20h 36m
Deal found 8/25![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 8/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:51 pm -
1 stop22h 57m
Deal found 8/26![Frontier logo]()
$127
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated August 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $177 (American Airlines) |
One-way from | $84 (Kiwi.com) |
Good round-trip deal | $462 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Sat 10/3
6:00 am-12:14 pm
1 stop6h 14m
Lambert-St Louis
Sat 10/10
7:01 pm-10:59 pm
1 stop3h 58m
$232
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Thu 10/8
7:10 pm-11:45 pm
1 stop4h 35m
Lambert-St Louis
Tue 10/13
4:05 pm-9:55 pm
1 stop5h 50m
$271
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Thu 10/8
7:10 pm-11:45 pm
1 stop4h 35m
Lambert-St Louis
Thu 10/15
2:30 pm-10:55 pm
2 stops8h 25m
$276
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Mon 9/28
5:40 am-10:30 am
1 stop4h 50m
Lambert-St Louis
Tue 9/29
2:50 pm-9:05 pm
2 stops6h 15m
$276
Quickest round-trip
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Sat 10/10
2:55 pm-4:05 pm
Nonstop1h 10m
Lambert-St Louis
Sat 10/17
8:25 am-9:40 am
Nonstop1h 15m
$277
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Mon 10/12
5:55 pm-7:05 pm
Nonstop1h 10m
Lambert-St Louis
Tue 10/13
8:50 pm-10:05 pm
Nonstop1h 15m
$277
Des MoinesSt. Louis
DSM Des Moines - STL Lambert-St Louis
DSMSTL
Des Moines
Tue 10/27
5:35 am-2:55 pm
2 stops9h 20m
Lambert-St Louis
Thu 10/29
1:05 pm-10:55 pm
2 stops9h 50m
$281
Cedar RapidsKansas City
CID Cedar Rapids - MCI Kansas City
CIDMCI
Cedar Rapids
Thu 10/8
8:34 pm-12:28 am
1 stop3h 54m
Kansas City
Mon 10/12
7:21 pm-12:20 am
1 stop4h 59m
$289
OmahaSt. Louis
OMA Omaha Eppley Airfield - STL Lambert-St Louis
OMASTL
Omaha Eppley Airfield
Sat 10/3
2:55 pm-4:05 pm
Nonstop1h 10m
Lambert-St Louis
Mon 10/5
6:10 pm-11:35 pm
1 stop5h 25m
$297
OmahaSpringfield
OMA Omaha Eppley Airfield - SGF Springfield-Branson
OMASGF
Omaha Eppley Airfield
Wed 9/23
5:32 pm-11:42 pm
1 stop6h 10m
Springfield-Branson
Wed 9/30
6:25 pm-10:59 pm
1 stop4h 34m
$299
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
OMA-STL
DSM-STL
CID-MCI
OMA-MCI
LSE-MCI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
OMA-STL
DSM-STL
CID-MCI
OMA-MCI
How much does it cost to fly round-trip from Iowa to Missouri?
Airfare is below average for this route at the moment.
Iowa to Missouri flights typically cost between $272 and $634 in October.The cheapest round-trip price found within the last 5 days was $271 on Southwest (Oct 8-Oct 15).
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated August 29, 2026.
Peruse reviews from past customers who have flown with Southwest,United Airlines, andAmerican Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Entertainment
7.5
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on August 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$107 | Average$272 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$158 | Average$464 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$258 | Average$368 | FlexibilityNo cancel fee | On-time69% |