$71+ Cheap flights from Iowa to Missouri
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/5. Fares are subject to change and may not be available on all flights or dates of travel.
DSM — STL
Apr 5 — Apr 121
Round-trip
1 adult, Economy
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Find cheap flights from Iowa to Missouri with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 6, 2026.
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 pm
DSM
- STL
1 stop6h 38m
Delta
Sun 4/126:29 am
STL
- DSM
1 stop3h 40m
Delta
Deal found 3/5![Delta logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:03 pm
OMA
- STL
2 stops26h 16m
Frontier
Sat 4/48:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/2![Frontier logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Sat 4/118:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/2![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:30 am
DSM
- STL
1 stop4h 05m
Southwest
Mon 4/62:30 pm
STL
- DSM
1 stop7h 50m
Southwest
Deal found 3/2![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/213:20 pm
OMA
- COU
1 stop6h 13m
United Airlines
Wed 3/258:00 am
COU
- OMA
1 stop6h 24m
United Airlines
Deal found 3/6![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:51 am
CID
- MCI
1 stop5h 09m
Delta
Tue 4/712:17 pm
MCI
- CID
1 stop3h 22m
Delta
Deal found 3/3![Delta logo]()
$259
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 am
DSM
- STL
1 stop5h 03m
American Airlines
Thu 4/24:13 pm
STL
- DSM
1 stop7h 29m
American Airlines
Deal found 3/2![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:20 pm
CID
- MCI
1 stop6h 43m
Delta
Sun 3/296:05 am
MCI
- CID
1 stop5h 06m
Delta
Deal found 3/6![Delta logo]()
$264
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:20 pm
DSM
- STL
1 stop6h 38m
Delta
Sun 3/296:29 am
STL
- DSM
1 stop3h 40m
Delta
Deal found 3/2![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:30 am
DSM
- STL
1 stop6h 10m
Southwest
Tue 4/72:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Deal found 3/2![Southwest logo]()
$266
This Southwest deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/86:10 am
DSM
- STL
2 stops8h 40m
Southwest
Wed 9/93:05 pm
STL
- DSM
2 stops6h 50m
Southwest
Deal found 3/1![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:25 am
DSM
- STL
1 stop4h 50m
Southwest
Sun 4/264:40 pm
STL
- DSM
1 stop6h 40m
Southwest
Deal found 3/3![Southwest logo]()
$272
Best flights from Iowa to MissouriDiscover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 6, 2026.
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 6, 2026.
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/244:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Sat 4/255:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/2![Southwest logo]()
$257
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/213:20 pm
OMA
- COU
1 stop6h 13m
United Airlines
Wed 3/258:00 am
COU
- OMA
1 stop6h 24m
United Airlines
Deal found 3/6![United Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:51 am
CID
- MCI
1 stop5h 09m
Delta
Tue 4/712:17 pm
MCI
- CID
1 stop3h 22m
Delta
Deal found 3/3![Delta logo]()
$259
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:59 pm
OMA
- MCI
1 stop22h 59m
Frontier
Thu 4/98:46 pm
MCI
- OMA
1 stop23h 28m
Frontier
Deal found 3/5![Frontier logo]()
$276
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/110:50 am
OMA
- SGF
1 stop6h 45m
American Airlines
Sun 5/35:19 am
SGF
- OMA
1 stop4h 51m
American Airlines
Deal found 3/2![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:51 pm
CID
- MCI
2 stops21h 18m
Multiple Airlines
Sun 4/128:28 pm
MCI
- CID
1 stop17h 29m
Multiple Airlines
Deal found 3/2![Multiple Airlines logo]()
$478
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/25:35 am
DSM
- STL
1 stop3h 25m
Southwest
Mon 4/62:30 pm
STL
- DSM
1 stop7h 50m
Southwest
Deal found 3/2![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:20 pm
CID
- MCI
1 stop6h 43m
Delta
Sun 3/296:05 am
MCI
- CID
1 stop5h 06m
Delta
Deal found 3/6![Delta logo]()
$264
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:20 am
OMA
- SGF
1 stop6h 04m
United Airlines
Tue 4/76:00 am
SGF
- OMA
1 stop4h 32m
United Airlines
Deal found 3/3![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/216:55 am
DSM
- STL
2 stops6h 05m
Southwest
Thu 4/234:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Deal found 3/2![Southwest logo]()
$262
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:20 pm
DSM
- STL
1 stop6h 38m
Delta
Mon 3/304:21 pm
STL
- DSM
1 stop6h 17m
Delta
Deal found 3/2![Delta logo]()
$265
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/285:30 am
DSM
- STL
1 stop4h 00m
Southwest
Mon 5/46:20 am
STL
- DSM
1 stop6h 50m
Southwest
Deal found 3/6![Southwest logo]()
$277
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/246:31 pm
DSM
- STL
1 stop5h 05m
Delta
Sat 4/251:03 pm
STL
- DSM
1 stop4h 42m
Delta
Deal found 3/3![Delta logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/79:15 am
CID
- MCI
1 stop7h 01m
United Airlines
Sat 4/119:00 am
MCI
- CID
1 stop5h 13m
United Airlines
Deal found 3/3![United Airlines logo]()
$319
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/111:45 pm
DSM
- STL
1 stop7h 20m
Southwest
Mon 5/185:40 am
STL
- DSM
1 stop6h 05m
Southwest
Deal found 3/5![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:05 am
OMA
- SGF
1 stop8h 22m
United Airlines
Sat 4/186:00 am
SGF
- OMA
1 stop4h 32m
United Airlines
Deal found 3/2![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/304:20 pm
DSM
- STL
1 stop6h 25m
Southwest
Mon 5/43:00 pm
STL
- DSM
1 stop6h 55m
Southwest
Deal found 3/3![Southwest logo]()
$277
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/177:00 pm
OMA
- SGF
1 stop5h 36m
United Airlines
Sun 4/198:00 am
SGF
- OMA
1 stop4h 47m
United Airlines
Deal found 3/2![United Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/75:40 am
DSM
- STL
1 stop3h 35m
Southwest
Sun 8/97:30 pm
STL
- DSM
1 stop3h 05m
Southwest
Deal found 3/5![Southwest logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/171:19 pm
OMA
- SGF
1 stop27h 45m
Allegiant Air
Sat 3/219:45 pm
SGF
- OMA
2 stops38h 03m
Allegiant Air
Deal found 3/2![Allegiant Air logo]()
$893
This Southwest deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/185:35 am
DSM
- STL
2 stops8h 00m
Southwest
Sat 4/255:40 am
STL
- DSM
1 stop5h 50m
Southwest
Deal found 3/4![Southwest logo]()
$282
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:37 pm
LSE
- STL
1 stop3h 42m
American Airlines
Thu 4/95:21 pm
STL
- LSE
1 stop6h 33m
American Airlines
Deal found 3/5![American Airlines logo]()
$506
This United Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:22 pm
OMA
- STL
1 stop5h 51m
United Airlines
Sun 4/126:30 am
STL
- OMA
1 stop4h 02m
United Airlines
Deal found 3/2![United Airlines logo]()
$348
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/175:25 am
DSM
- STL
2 stops9h 30m
Southwest
Fri 4/244:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Deal found 3/3![Southwest logo]()
$292
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:20 am
ALO
- STL
1 stop3h 31m
American Airlines
Tue 3/246:37 pm
STL
- ALO
1 stop5h 16m
American Airlines
Deal found 3/5![American Airlines logo]()
$538
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:00 am
OMA
- COU
1 stop6h 48m
United Airlines
Wed 4/299:02 am
COU
- OMA
1 stop7h 18m
United Airlines
Deal found 3/5![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Mon 4/69:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/3![Southwest logo]()
$308
This American Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:29 pm
LSE
- STL
1 stop5h 15m
American Airlines
Sun 3/226:00 am
STL
- LSE
1 stop5h 02m
American Airlines
Deal found 3/3![American Airlines logo]()
$551
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/11:55 pm
OMA
- STL
1 stop6h 00m
Southwest
Wed 4/88:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 3/3![Southwest logo]()
$311
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/205:09 am
LSE
- STL
1 stop3h 42m
American Airlines
Tue 3/247:05 am
STL
- LSE
2 stops10h 54m
American Airlines
Deal found 3/5![American Airlines logo]()
$557
Last-minute flights from Iowa to MissouriDiscover last-minute flight deals from Iowa to Missouri. Data last updated March 6, 2026 and is based on user searches.
Discover last-minute flight deals from Iowa to Missouri. Data last updated March 6, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/213:20 pm
OMA
- COU
1 stop6h 13m
United Airlines
Wed 3/258:00 am
COU
- OMA
1 stop6h 24m
United Airlines
Deal found 3/6![United Airlines logo]()
$258
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/245:30 am
DSM
- STL
1 stop6h 10m
Southwest
Tue 4/72:30 pm
STL
- DSM
2 stops7h 40m
Southwest
Deal found 3/2![Southwest logo]()
$266
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:20 pm
CID
- MCI
1 stop6h 43m
Delta
Sun 3/296:05 am
MCI
- CID
1 stop5h 06m
Delta
Deal found 3/6![Delta logo]()
$264
This American Airlines deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/265:00 am
DSM
- STL
1 stop5h 03m
American Airlines
Thu 4/24:13 pm
STL
- DSM
1 stop7h 29m
American Airlines
Deal found 3/2![American Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/275:20 pm
DSM
- STL
1 stop6h 38m
Delta
Mon 3/304:21 pm
STL
- DSM
1 stop6h 17m
Delta
Deal found 3/2![Delta logo]()
$265
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/309:03 pm
OMA
- STL
2 stops26h 16m
Frontier
Sat 4/48:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/2![Frontier logo]()
$238
This Delta deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:51 am
CID
- MCI
1 stop5h 09m
Delta
Tue 4/712:17 pm
MCI
- CID
1 stop3h 22m
Delta
Deal found 3/3![Delta logo]()
$259
This United Airlines deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:20 am
OMA
- SGF
1 stop6h 04m
United Airlines
Tue 4/76:00 am
SGF
- OMA
1 stop4h 32m
United Airlines
Deal found 3/3![United Airlines logo]()
$274
This Southwest deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/15:30 am
DSM
- STL
1 stop4h 05m
Southwest
Mon 4/62:30 pm
STL
- DSM
1 stop7h 50m
Southwest
Deal found 3/2![Southwest logo]()
$257
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:20 pm
DSM
- STL
1 stop6h 38m
Delta
Sun 4/126:29 am
STL
- DSM
1 stop3h 40m
Delta
Deal found 3/5![Delta logo]()
$237
This Kiwi.com deal was found by Cheapflights users on 3/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/108:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Sat 4/118:16 pm
STL
- OMA
1 stop23h 58m
Frontier
Deal found 3/2![Frontier logo]()
$247
This Southwest deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:25 am
DSM
- STL
1 stop4h 50m
Southwest
Sun 4/264:40 pm
STL
- DSM
1 stop6h 40m
Southwest
Deal found 3/3![Southwest logo]()
$272
One-way flights from Iowa to MissouriSearch for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated March 6, 2026.
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated March 6, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/58:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/6![Frontier logo]()
$71
This Frontier deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/12:04 pm
DSM
- STL
1 stop5h 17m
Frontier
Deal found 3/3![Frontier logo]()
$80
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:58 pm
OMA
- STL
1 stop22h 23m
Frontier
Deal found 3/3![Frontier logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/18:49 pm
OMA
- STL
1 stop22h 43m
Frontier
Deal found 3/5![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/78:59 pm
OMA
- STL
1 stop22h 13m
Frontier
Deal found 3/6![Frontier logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/6![Frontier logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:14 pm
DSM
- STL
1 stop13h 34m
Frontier
Deal found 3/3![Frontier logo]()
$100
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:43 pm
OMA
- STL
2 stops34h 07m
Frontier
Deal found 3/4![Frontier logo]()
$104
This Delta deal was found by Cheapflights users on 3/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
DSM
- STL
1 stop4h 39m
Delta
Deal found 3/1![Delta logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:58 pm
OMA
- STL
2 stops33h 52m
Frontier
Deal found 3/6![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 3/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/38:59 pm
OMA
- STL
1 stop12h 49m
Frontier
Deal found 3/4![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/178:49 pm
OMA
- MCI
1 stop17h 17m
Frontier
Deal found 3/3![Frontier logo]()
$114
Find flight deals from Iowa to Missouri
Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated March 6, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $237 (Delta) |
One-way from | $71 (Kiwi.com) |
Popular in | February |
Cheapest in | September |
Average price | $298 |
Good round-trip deal | $105 or less |
Good one-way deal | $236 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Iowa to Missouri that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
Use the filters below to find and compare flights from Iowa to Missouri that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 4/24
4:20 pm-10:45 pm
1 stop6h 25m
Lambert-St Louis
Sat 4/25
5:40 am-11:30 am
1 stop5h 50m
$257
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Thu 4/2
5:35 am-9:00 am
1 stop3h 25m
Lambert-St Louis
Mon 4/6
2:30 pm-10:20 pm
1 stop7h 50m
$257
OmahaColumbia
OMA - COU
OMACOU
Omaha Eppley Airfield
Sat 3/21
3:20 pm-9:33 pm
1 stop6h 13m
Columbia Regional
Wed 3/25
8:00 am-2:24 pm
1 stop6h 24m
$258
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Tue 3/31
11:51 am-5:00 pm
1 stop5h 09m
Kansas City
Tue 4/7
12:17 pm-3:39 pm
1 stop3h 22m
$259
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 4/21
6:55 am-1:00 pm
2 stops6h 05m
Lambert-St Louis
Thu 4/23
4:40 pm-11:05 pm
1 stop6h 25m
$262
Cedar RapidsKansas City
CID - MCI
CIDMCI
Cedar Rapids
Wed 3/25
4:20 pm-11:03 pm
1 stop6h 43m
Kansas City
Sun 3/29
6:05 am-11:11 am
1 stop5h 06m
$264
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Fri 3/27
5:20 pm-11:58 pm
1 stop6h 38m
Lambert-St Louis
Mon 3/30
4:21 pm-10:38 pm
1 stop6h 17m
$265
OmahaSpringfield
OMA - SGF
OMASGF
Omaha Eppley Airfield
Tue 3/31
11:20 am-5:24 pm
1 stop6h 04m
Springfield-Branson
Tue 4/7
6:00 am-10:32 am
1 stop4h 32m
$274
OmahaKansas City
OMA - MCI
OMAMCI
Omaha Eppley Airfield
Thu 4/2
8:59 pm-7:58 pm
1 stop22h 59m
Kansas City
Thu 4/9
8:46 pm-8:14 pm
1 stop23h 28m
$276
Des MoinesSt. Louis
DSM - STL
DSMSTL
Des Moines
Tue 4/28
5:30 am-9:30 am
1 stop4h 00m
Lambert-St Louis
Mon 5/4
6:20 am-1:10 pm
1 stop6h 50m
$277
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Iowa to Missouri
Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.
DSM-STL
OMA-COU
CID-MCI
OMA-MCI
OMA-SGF
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Iowa to Missouri
USIA-USMO
DSM-STL
OMA-COU
CID-MCI
OMA-MCI
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $93). Flying from Iowa to Missouri in January is currently the most expensive (average of $275). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from IA to MO?
Find hourly flight availability from Iowa to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 6, 2026.
When flying from Iowa to Missouri, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Reviews of airlines servicing Missouri
Get insights into the airlines that provide service to Missouri. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Missouri. Reviews last updated March 6, 2026.
Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Comfort
8.0
Overall
8.0
Boarding
8.1
Food
7.0
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
10.0
ExcellentAnonymous,Mar 2026
KOA - HNL
Related info for your journey
Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Iowa to Missouri
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Complete your trip
Complete your trip to Missouri by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Iowa to Missouri by cabin class
Find flights from Iowa to Missouri, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Iowa and Missouri flights
Browse other Iowa and Missouri flight options. Last updated on March 6, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Missouri
Find the right flight back to Iowa after your stay in Missouri
Iowa to Missouri flights
Consider these flights traveling from Iowa to Missouri.
Top 3 airlines flying from Iowa to Missouri
Discover the top 3 airlines that operate flights from Iowa to Missouri. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 6, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$250 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$394 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$218 | Average$297 | FlexibilityNo cancel fee | On-time71% |