How popular is this Iowa to Missouri flight route?

Within the past month, 29 users have taken a look at flights from Iowa to Missouri.

How long is the flight from Iowa to Missouri?

A quick flight from Iowa to Missouri can take about 1h 05m. Delta provides one of the quickest options available for as low as $213. The distance between Iowa and Missouri is about 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

In terms of precipitation, rainfall in Missouri ranges from 2.2 - 4.7 inches per month. May is typically the wettest month, when rainfall can reach 4.7 in. February is typically the driest time to visit Missouri when rainfall is around 2.2 in.

If weather is an important factor for your trip to Missouri, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 80.6 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 32.0 F).

Can I find deals for flights from Iowa to Missouri that include hotel bookings?

Yes. In addition to deals on Iowa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Iowa to Missouri?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Missouri.

Can I find deals for business class flights from Iowa to Missouri?

Yes. Cheapflights offers flight deals from Iowa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$49+ Cheap Flights from Iowa to Missouri

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Find cheap flights from Iowa to Missouri with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

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Cheap flight deals from Iowa to Missouri

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$187 (Kiwi.com)
One-way from	$49 (Southwest)
Popular in	July
Cheapest in	September
Average price	$228
Good round-trip deal	$105 or less
Good one-way deal	$154 or less

Provider with most accurate pricing for Des Moines-Lambert-St Louis flight deals.

Search Deals

Provider most trusted by Cheapflights users for Des Moines-Lambert-St Louis flights.

Search Deals

From Iowa to Missouri

Search Deals

One-way flight from Iowa to Missouri

Search Deals

Highest demand for flights based on searches. 10% potential increase in price ($38 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 7% potential price decrease ($23 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in October 2025

Search Deals

Price to beat on a round-trip flight from Iowa to Missouri.

Search Deals

Price to beat on a one-way flight from Iowa to Missouri.

Search Deals

Find flight deals from Iowa to Missouri

Cheapest flights from Iowa to Missouri
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Fri 11/142:34 pmDSM - STL

1 stop18h 33mFrontier

Sat 11/157:45 pmSTL - DSM

1 stop18h 02mFrontier

Deal found 10/16

$187

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sat 11/18:40 pmSTL - OMA

1 stop23h 11mFrontier

Deal found 10/15

$197

Mon 12/16:50 pmDSM - STL

Nonstop1h 05mSouthwest

Wed 12/38:25 pmSTL - DSM

Nonstop1h 10mSouthwest

Deal found 10/15

$213

Sat 11/13:20 pmOMA - COU

1 stop5h 59mUnited Airlines

Wed 11/53:02 pmCOU - OMA

1 stop6h 50mUnited Airlines

Deal found 10/16

$218

Tue 11/114:22 pmCID - MCI

1 stop6h 44mDelta

Sat 11/156:40 amMCI - CID

1 stop5h 08mDelta

Deal found 10/15

$219

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sun 11/27:45 pmSTL - OMA

1 stop24h 21mFrontier

Deal found 10/15

$223

Thu 10/301:46 pmCID - MCI

1 stop7h 43mAmerican Airlines

Sun 11/25:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/15

$229

Fri 10/316:00 amALO - STL

1 stop3h 43mAmerican Airlines

Tue 11/43:38 pmSTL - ALO

1 stop4h 19mAmerican Airlines

Deal found 10/16

$229

Fri 11/146:40 pmDSM - STL

1 stop5h 16mAmerican Airlines

Sat 11/158:39 amSTL - DSM

1 stop6h 53mAmerican Airlines

Deal found 10/14

$235

Fri 10/3111:27 amOMA - SGF

1 stop6h 19mUnited Airlines

Tue 11/48:00 amSGF - OMA

1 stop6h 21mUnited Airlines

Deal found 10/16

$239

Tue 10/216:00 amCID - MCI

1 stop7h 00mAmerican Airlines

Mon 11/106:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/16

$239

Fri 10/312:32 pmDSM - STL

1 stop18h 35mMultiple Airlines

Tue 11/47:45 pmSTL - DSM

2 stops51h 18mMultiple Airlines

Deal found 10/16

$240

Best flights from Iowa to Missouri
Discover carefully curated flight deals from Iowa to Missouri that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 16, 2025.

Tue 3/35:15 pmDSM - STL

1 stop6h 25mDelta

Wed 3/46:30 amSTL - DSM

1 stop3h 52mDelta

Deal found 10/14

$181

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sat 11/18:40 pmSTL - OMA

1 stop23h 11mFrontier

Deal found 10/15

$197

Mon 12/16:50 pmDSM - STL

Nonstop1h 05mSouthwest

Wed 12/38:25 pmSTL - DSM

Nonstop1h 10mSouthwest

Deal found 10/15

$213

Sat 11/13:20 pmOMA - COU

1 stop5h 59mUnited Airlines

Wed 11/53:02 pmCOU - OMA

1 stop6h 50mUnited Airlines

Deal found 10/16

$218

Thu 10/301:46 pmCID - MCI

1 stop7h 43mAmerican Airlines

Sun 11/25:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/15

$229

Fri 10/3111:45 amOMA - STL

2 stops21h 22mMultiple Airlines

Sat 11/18:40 pmSTL - OMA

1 stop23h 11mMultiple Airlines

Deal found 10/15

$310

Mon 10/277:40 pmOMA - SGF

1 stop18h 58mAllegiant Air

Thu 10/305:47 pmSGF - OMA

1 stop25h 20mAllegiant Air

Deal found 10/16

$358

Tue 11/114:22 pmCID - MCI

1 stop6h 44mDelta

Sat 11/1510:37 amMCI - CID

1 stop5h 05mDelta

Deal found 10/14

$219

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sun 11/27:45 pmSTL - OMA

1 stop24h 21mFrontier

Deal found 10/15

$223

Fri 10/316:00 amALO - STL

1 stop3h 43mAmerican Airlines

Tue 11/43:38 pmSTL - ALO

1 stop4h 19mAmerican Airlines

Deal found 10/16

$229

Fri 10/3111:27 amOMA - SGF

1 stop6h 19mUnited Airlines

Tue 11/48:00 amSGF - OMA

1 stop6h 21mUnited Airlines

Deal found 10/16

$239

Fri 11/145:45 amDSM - STL

Nonstop1h 20mSouthwest

Sat 11/151:45 pmSTL - DSM

Nonstop1h 10mSouthwest

Deal found 10/14

$250

Fri 11/146:40 pmDSM - STL

1 stop5h 16mAmerican Airlines

Sat 11/158:39 amSTL - DSM

1 stop6h 53mAmerican Airlines

Deal found 10/14

$235

Mon 12/14:59 pmDSM - STL

1 stop6h 24mDelta

Wed 12/32:38 pmSTL - DSM

1 stop6h 08mDelta

Deal found 10/15

$255

Fri 10/315:26 pmCID - MCI

1 stop4h 24mUnited Airlines

Tue 11/46:00 amMCI - CID

1 stop4h 35mUnited Airlines

Deal found 10/13

$260

Tue 10/216:00 amCID - MCI

1 stop7h 00mAmerican Airlines

Mon 11/106:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/16

$239

Mon 12/14:59 pmDSM - STL

1 stop6h 24mDelta

Mon 12/85:34 pmSTL - DSM

1 stop3h 41mDelta

Deal found 10/16

$255

Thu 11/206:00 amOMA - STL

Nonstop1h 25mSouthwest

Sat 11/2210:45 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 10/15

$286

Tue 3/241:45 pmOMA - COU

1 stop6h 45mUnited Airlines

Sat 3/289:00 amCOU - OMA

1 stop7h 10mUnited Airlines

Deal found 10/15

$268

Thu 12/187:15 amOMA - STL

1 stop6h 08mAmerican Airlines

Mon 12/226:35 pmSTL - OMA

1 stop5h 24mAmerican Airlines

Deal found 10/14

$273

Fri 11/73:12 pmCID - MCI

1 stop5h 35mUnited Airlines

Mon 11/101:47 pmMCI - CID

2 stops7h 42mUnited Airlines

Deal found 10/14

$284

Thu 11/136:15 pmDSM - MCI

1 stop5h 25mSouthwest

Thu 11/204:10 pmMCI - DSM

1 stop5h 25mSouthwest

Deal found 10/14

$327

Fri 11/75:55 pmCID - MCI

1 stop5h 12mAmerican Airlines

Mon 11/107:43 pmMCI - CID

1 stop3h 45mAmerican Airlines

Deal found 10/14

$279

Wed 10/298:53 amCID - MCI

1 stop7h 12mUnited Airlines

Sun 11/25:00 amMCI - CID

1 stop4h 35mUnited Airlines

Deal found 10/14

$289

Thu 10/3011:00 amOMA - STL

1 stop6h 00mSouthwest

Tue 12/28:25 pmSTL - OMA

Nonstop1h 20mSouthwest

Deal found 10/15

$334

Sun 12/288:33 pmDSM - MCI

1 stop22h 59mFrontier

Sat 1/38:27 pmMCI - DSM

1 stop23h 11mFrontier

Deal found 10/14

$434

Thu 11/276:30 amCID - MCI

1 stop4h 10mUnited Airlines

Sat 11/296:35 pmMCI - CID

1 stop6h 35mUnited Airlines

Deal found 10/15

$316

Fri 10/242:37 pmDSM - MCI

1 stop5h 16mFrontier

Sat 10/257:02 pmMCI - DSM

1 stop18h 50mFrontier

Deal found 10/14

$442

Thu 10/305:05 amOMA - STL

1 stop6h 47mAmerican Airlines

Tue 12/27:00 amSTL - OMA

1 stop7h 44mAmerican Airlines

Deal found 10/15

$334

Wed 10/296:20 amDSM - MCI

1 stop5h 05mSouthwest

Thu 10/303:25 pmMCI - DSM

1 stop6h 10mSouthwest

Deal found 10/14

$411

Last-minute flights from Iowa to Missouri
Discover last-minute flight deals from Iowa to Missouri. Data last updated October 16, 2025 and is based on user searches.

Tue 10/216:00 amCID - MCI

1 stop7h 00mAmerican Airlines

Mon 11/106:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/16

$239

Thu 10/301:46 pmCID - MCI

1 stop7h 43mAmerican Airlines

Sun 11/25:05 amMCI - CID

1 stop4h 54mAmerican Airlines

Deal found 10/15

$229

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sat 11/18:40 pmSTL - OMA

1 stop23h 11mFrontier

Deal found 10/15

$197

Fri 10/318:51 pmOMA - STL

1 stop12h 16mFrontier

Sun 11/27:45 pmSTL - OMA

1 stop24h 21mFrontier

Deal found 10/15

$223

Fri 10/316:00 amALO - STL

1 stop3h 43mAmerican Airlines

Tue 11/43:38 pmSTL - ALO

1 stop4h 19mAmerican Airlines

Deal found 10/16

$229

Fri 10/3111:27 amOMA - SGF

1 stop6h 19mUnited Airlines

Tue 11/48:00 amSGF - OMA

1 stop6h 21mUnited Airlines

Deal found 10/16

$239

Fri 10/312:32 pmDSM - STL

1 stop18h 35mMultiple Airlines

Tue 11/47:45 pmSTL - DSM

2 stops51h 18mMultiple Airlines

Deal found 10/16

$240

Sat 11/13:20 pmOMA - COU

1 stop5h 59mUnited Airlines

Wed 11/53:02 pmCOU - OMA

1 stop6h 50mUnited Airlines

Deal found 10/16

$218

Tue 11/114:22 pmCID - MCI

1 stop6h 44mDelta

Sat 11/156:40 amMCI - CID

1 stop5h 08mDelta

Deal found 10/15

$219

Fri 11/142:34 pmDSM - STL

1 stop18h 33mFrontier

Sat 11/157:45 pmSTL - DSM

1 stop18h 02mFrontier

Deal found 10/16

$187

Fri 11/146:40 pmDSM - STL

1 stop5h 16mAmerican Airlines

Sat 11/158:39 amSTL - DSM

1 stop6h 53mAmerican Airlines

Deal found 10/14

$235

Fri 11/145:45 amDSM - STL

Nonstop1h 20mSouthwest

Sat 11/151:45 pmSTL - DSM

Nonstop1h 10mSouthwest

Deal found 10/14

$250

One-way flights from Iowa to Missouri
Search for one-way flight options from Iowa to Missouri. Find affordable one-way fares based on user searches. Data last updated October 16, 2025.

Wed 1/143:20 pmDSM - STL

Nonstop1h 15mSouthwest

Deal found 10/15

$49

Mon 11/102:32 pmDSM - STL

1 stop18h 35mFrontier

Deal found 10/16

$61

Thu 2/56:25 amDSM - STL

1 stop10h 45mSouthwest

Deal found 10/15

$64

Mon 11/172:32 pmDSM - STL

1 stop18h 35mFrontier

Deal found 10/16

$67

Fri 11/142:34 pmDSM - STL

1 stop18h 33mFrontier

Deal found 10/16

$68

Fri 11/148:51 pmOMA - STL

1 stop12h 16mFrontier

Deal found 10/15

$72

Tue 11/185:00 amDSM - STL

1 stop5h 39mAmerican Airlines

Deal found 10/15

$80

Mon 11/178:51 pmOMA - STL

1 stop12h 16mFrontier

Deal found 10/16

$81

Thu 11/132:41 pmDSM - STL

1 stop18h 26mFrontier

Deal found 10/16

$84

Thu 11/275:45 amDSM - STL

Nonstop1h 20mSouthwest

Deal found 10/15

$86

Sun 11/167:46 pmOMA - STL

1 stop13h 21mFrontier

Deal found 10/16

$89

Sat 1/3111:35 amDSM - STL

1 stop4h 39mAmerican Airlines

Deal found 10/15

$90

Fly from

Fly to

Route

Depart

Return

Price

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Tue 3/3

5:15 pm-11:40 pm

1 stop6h 25m

Lambert-St Louis

Wed 3/4

6:30 am-10:22 am

1 stop3h 52m

$181

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 10/31

8:51 pm-9:07 am

1 stop12h 16m

Lambert-St Louis

Sat 11/1

8:40 pm-7:51 pm

1 stop23h 11m

$197

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Mon 12/1

6:50 pm-7:55 pm

Nonstop1h 05m

Lambert-St Louis

Wed 12/3

8:25 pm-9:35 pm

Nonstop1h 10m

$213

OmahaColumbia

OMA - COU

OMACOU

Omaha Eppley Airfield

Sat 11/1

3:20 pm-9:19 pm

1 stop5h 59m

Columbia Regional

Wed 11/5

3:02 pm-9:52 pm

1 stop6h 50m

$218

Cedar RapidsKansas City

CID - MCI

CIDMCI

Cedar Rapids

Tue 11/11

4:22 pm-11:06 pm

1 stop6h 44m

Kansas City

Sat 11/15

10:37 am-3:42 pm

1 stop5h 05m

$219

OmahaSt. Louis

OMA - STL

OMASTL

Omaha Eppley Airfield

Fri 10/31

8:51 pm-9:07 am

1 stop12h 16m

Lambert-St Louis

Sun 11/2

7:45 pm-8:06 pm

1 stop24h 21m

$223

Cedar RapidsKansas City

CID - MCI

CIDMCI

Cedar Rapids

Thu 10/30

1:46 pm-9:29 pm

1 stop7h 43m

Kansas City

Sun 11/2

5:05 am-9:59 am

1 stop4h 54m

$229

WaterlooSt. Louis

ALO - STL

ALOSTL

Waterloo

Fri 10/31

6:00 am-9:43 am

1 stop3h 43m

Lambert-St Louis

Tue 11/4

3:38 pm-7:57 pm

1 stop4h 19m

$229

Des MoinesSt. Louis

DSM - STL

DSMSTL

Des Moines

Fri 11/14

6:40 pm-11:56 pm

1 stop5h 16m

Lambert-St Louis

Sat 11/15

8:39 am-3:32 pm

1 stop6h 53m

$235

OmahaSpringfield

OMA - SGF

OMASGF

Omaha Eppley Airfield

Fri 10/31

11:27 am-5:46 pm

1 stop6h 19m

Springfield-Branson

Tue 11/4

8:00 am-2:21 pm

1 stop6h 21m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/16

Showing 1-10 of 60 results

...

Best time to book a flight from Iowa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Missouri

What is the cheapest month to book a flight from Iowa to Missouri?

Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $92). Flying from Iowa to Missouri in December is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IA to MO?

It’s optimal to fly from Iowa to Missouri in the evening. By choosing this option you can save up to 27% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southwest

8.0

Very good

4,241 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

United Airlines

7.4

Good

8,980 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

American Airlines

7.2

Good

11,042 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Southern / Mokulele

6.2

Okay

26 reviews

Southwest

8.0

Very good

4,241 reviews

Reviews

1 / 20

2.0

Mediocre

Mike,Aug 2025

OKC - AUS

AC was not adequate, even on a night flight. WiFi subpar even for the airlines

Related info for your journey

How popular is this Iowa to Missouri flight route?
Within the past month, 29 users have taken a look at flights from Iowa to Missouri.
How long is the flight from Iowa to Missouri?
A quick flight from Iowa to Missouri can take about 1h 05m. Delta provides one of the quickest options available for as low as $213. The distance between Iowa and Missouri is about 259 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.
Can I find deals for flights from Iowa to Missouri that include hotel bookings?
Yes. In addition to deals on Iowa to Missouri flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Iowa to Missouri?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Iowa to Missouri.
Can I find deals for business class flights from Iowa to Missouri?
Yes. Cheapflights offers flight deals from Iowa to Missouri by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Iowa to Missouri?
Currently, October is the cheapest month in which you can book a flight from Iowa to Missouri (average of $92). Flying from Iowa to Missouri in December is currently the most expensive (average of $245). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Top 4 airlines flying from Iowa to Missouri

Airline	Cheapest	Average	Flexibility	On-time
Southern / Mokulele	Cheapest$61	Average$85	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$97	Average$290	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$218	Average$303	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$218	Average$418	FlexibilityNo cancel fee	On-time69%

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$49+ Cheap flights from Iowa to Missouri

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Iowa to Missouri with Cheapflights

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Cheap flight deals from Iowa to Missouri

Keep the following information in mind while searching for Iowa to Missouri flight deals. Data was last updated October 16, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Good round-trip deal

Good one-way deal

Find flight deals from Iowa to Missouri

Cheapest flights from Iowa to MissouriExplore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.

Cheapflights Fare Finder

Use the filters below to find and compare flights from Iowa to Missouri that are best for you.

Best time to book a flight from Iowa to Missouri

Have a flexible travel schedule? Discover the best time to fly to Missouri from Iowa with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Iowa to Missouri

What is the cheapest month to book a flight from Iowa to Missouri?

What is the cheapest time of day to fly from IA to MO?

Find hourly flight availability from Iowa to Missouri. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 16, 2025.

Reviews of airlines servicing Missouri

Peruse reviews from past customers who have flown with Southwest, United Airlines, and American Airlines from Iowa to Missouri to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Iowa to Missouri. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How popular is this Iowa to Missouri flight route?

How long is the flight from Iowa to Missouri?

Can I find deals for flights from Iowa to Missouri that include hotel bookings?

How can I find direct flights from Iowa to Missouri?

Can I find deals for business class flights from Iowa to Missouri?

What is the cheapest month to book a flight from Iowa to Missouri?

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Iowa to Missouri

See prices for flight routes from nearby airports that may be better suited for you.

Top 4 airlines flying from Iowa to Missouri

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Travel Smart

Cheapest flights from Iowa to Missouri
Explore the most affordable flight options available from Iowa to Missouri. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 16, 2025.