$65+ Cheap flights from Missouri to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Jun 8 — Jun 151
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Iowa with Cheapflights
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Cheapest flights from Missouri to IowaExplore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 9, 2026.
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Sat 6/68:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/8![Frontier logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- OMA
2 stops25h 00m
Frontier
Mon 6/87:56 pm
OMA
- MCI
1 stop17h 04m
Frontier
Deal found 5/4![Frontier logo]()
$232
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Fri 6/268:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Deal found 5/8![Frontier logo]()
$242
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Mon 6/18:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/5![Frontier logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- DSM
2 stops28h 34m
Multiple Airlines
Wed 6/102:16 pm
DSM
- MCI
1 stop22h 44m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$247
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Mon 6/158:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 5/8![Frontier logo]()
$260
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/308:50 pm
STL
- OMA
Nonstop1h 15m
Southwest
Sat 10/33:20 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 5/6![Southwest logo]()
$267
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Mon 6/15:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 5/5![Southwest logo]()
$269
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:29 pm
STL
- OMA
1 stop4h 35m
United Airlines
Wed 6/33:13 pm
OMA
- STL
1 stop6h 17m
United Airlines
Deal found 5/7![United Airlines logo]()
$275
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:42 pm
MCI
- MLI
1 stop4h 32m
American Airlines
Tue 6/94:45 pm
MLI
- MCI
1 stop7h 40m
American Airlines
Deal found 5/5![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:20 am
STL
- DSM
1 stop4h 25m
Southwest
Wed 5/276:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 5/4![Southwest logo]()
$288
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:35 am
STL
- OMA
1 stop6h 40m
Southwest
Wed 6/32:05 pm
OMA
- STL
2 stops7h 10m
Southwest
Deal found 5/7![Southwest logo]()
$290
Best flights from Missouri to IowaDiscover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
Discover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- DSM
2 stops28h 34m
Multiple Airlines
Wed 6/102:16 pm
DSM
- MCI
1 stop22h 44m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:30 am
STL
- OMA
Nonstop1h 20m
Southwest
Mon 6/14:50 pm
OMA
- STL
1 stop7h 00m
Southwest
Deal found 5/5![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:42 pm
MCI
- MLI
1 stop4h 32m
American Airlines
Tue 6/94:45 pm
MLI
- MCI
1 stop7h 40m
American Airlines
Deal found 5/5![American Airlines logo]()
$279
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:08 am
STL
- DSM
1 stop6h 27m
Delta
Thu 6/115:35 am
DSM
- STL
1 stop6h 59m
Delta
Deal found 5/4![Delta logo]()
$298
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/35:10 am
STL
- FOD
1 stop5h 27m
United Airlines
Wed 10/711:13 am
FOD
- STL
1 stop4h 08m
United Airlines
Deal found 5/6![United Airlines logo]()
$344
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:35 am
STL
- DSM
1 stop5h 50m
Southwest
Sat 6/66:55 pm
DSM
- STL
1 stop4h 50m
Southwest
Deal found 5/4![Southwest logo]()
$288
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:49 pm
MCI
- MLI
1 stop4h 05m
American Airlines
Sat 5/236:00 am
MLI
- MCI
1 stop7h 07m
American Airlines
Deal found 5/4![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/104:00 pm
STL
- DSM
1 stop5h 40m
Southwest
Sun 6/145:10 am
DSM
- STL
1 stop4h 20m
Southwest
Deal found 5/7![Southwest logo]()
$305
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:10 am
STL
- OMA
1 stop7h 32m
United Airlines
Wed 6/36:40 pm
OMA
- STL
1 stop4h 49m
United Airlines
Deal found 5/6![United Airlines logo]()
$345
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:15 pm
STL
- DSM
1 stop3h 55m
Southwest
Thu 8/133:50 pm
DSM
- STL
1 stop6h 15m
Southwest
Deal found 5/8![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:00 am
MCI
- MLI
1 stop3h 59m
United Airlines
Fri 6/126:30 pm
MLI
- MCI
1 stop4h 43m
United Airlines
Deal found 5/7![United Airlines logo]()
$359
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/46:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Sun 6/75:10 am
DSM
- STL
1 stop4h 20m
Southwest
Deal found 5/6![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:35 pm
SGF
- MLI
1 stop5h 39m
United Airlines
Sat 8/226:30 am
MLI
- SGF
1 stop4h 13m
United Airlines
Deal found 5/6![United Airlines logo]()
$359
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/208:53 am
STL
- OMA
1 stop3h 32m
Delta
Sat 5/235:45 pm
OMA
- STL
1 stop5h 36m
Delta
Deal found 5/4![Delta logo]()
$451
This Southwest deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/284:40 pm
STL
- DSM
1 stop6h 25m
Southwest
Fri 5/295:25 am
DSM
- STL
2 stops9h 30m
Southwest
Deal found 5/6![Southwest logo]()
$312
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/267:53 pm
SGF
- LSE
1 stop4h 26m
American Airlines
Wed 7/85:53 pm
LSE
- SGF
1 stop4h 44m
American Airlines
Deal found 5/4![American Airlines logo]()
$424
This Delta deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/225:36 pm
STL
- OMA
1 stop5h 20m
Delta
Mon 5/256:34 am
OMA
- STL
1 stop3h 58m
Delta
Deal found 5/6![Delta logo]()
$451
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/45:40 am
STL
- DSM
1 stop5h 50m
Southwest
Thu 6/114:40 pm
DSM
- STL
2 stops6h 05m
Southwest
Deal found 5/7![Southwest logo]()
$312
This United Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:17 am
MCI
- MLI
1 stop3h 47m
United Airlines
Sat 5/233:47 pm
MLI
- MCI
1 stop4h 00m
United Airlines
Deal found 5/4![United Airlines logo]()
$379
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:21 am
STL
- OMA
1 stop3h 54m
Delta
Sat 5/235:45 pm
OMA
- STL
1 stop5h 36m
Delta
Deal found 5/4![Delta logo]()
$451
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/910:15 am
STL
- DSM
2 stops12h 30m
Southwest
Thu 6/114:40 pm
DSM
- STL
2 stops6h 05m
Southwest
Deal found 5/4![Southwest logo]()
$314
This American Airlines deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/237:39 pm
SGF
- LSE
1 stop4h 27m
American Airlines
Wed 5/275:34 pm
LSE
- SGF
1 stop5h 06m
American Airlines
Deal found 5/8![American Airlines logo]()
$498
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/125:29 pm
STL
- OMA
1 stop6h 15m
United Airlines
Sun 6/146:40 pm
OMA
- STL
1 stop4h 49m
United Airlines
Deal found 5/6![United Airlines logo]()
$413
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/155:55 pm
STL
- DSM
1 stop5h 35m
Southwest
Sat 10/175:40 am
DSM
- STL
1 stop6h 05m
Southwest
Deal found 5/4![Southwest logo]()
$317
This American Airlines deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:53 pm
SGF
- LSE
1 stop15h 14m
American Airlines
Fri 6/265:25 pm
LSE
- SGF
1 stop20h 23m
American Airlines
Deal found 5/7![American Airlines logo]()
$504
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:00 am
MCI
- MLI
1 stop3h 59m
United Airlines
Sat 6/136:30 pm
MLI
- MCI
1 stop4h 43m
United Airlines
Deal found 5/6![United Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/176:30 pm
STL
- DSM
1 stop5h 00m
Southwest
Sun 7/194:15 pm
DSM
- STL
1 stop6h 35m
Southwest
Deal found 5/7![Southwest logo]()
$321
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/255:31 am
MCI
- MLI
1 stop5h 08m
American Airlines
Thu 6/254:45 pm
MLI
- MCI
1 stop5h 14m
American Airlines
Deal found 5/4![American Airlines logo]()
$519
This Southwest deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:25 am
STL
- OMA
1 stop7h 10m
Southwest
Sat 6/64:45 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 5/8![Southwest logo]()
$341
This United Airlines deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
STL
- FOD
3 stops28h 37m
United Airlines
Sun 7/2611:07 am
FOD
- STL
1 stop4h 39m
United Airlines
Deal found 5/6![United Airlines logo]()
$477
Last-minute flights from Missouri to IowaDiscover last-minute flight deals from Missouri to Iowa. Data last updated May 9, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Iowa. Data last updated May 9, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/235:11 pm
STL
- DSM
1 stop6h 46m
American Airlines
Wed 5/274:48 pm
DSM
- STL
1 stop4h 54m
American Airlines
Deal found 5/4![American Airlines logo]()
$302
This Southwest deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/257:20 am
STL
- DSM
1 stop4h 25m
Southwest
Wed 5/276:30 pm
DSM
- STL
1 stop4h 40m
Southwest
Deal found 5/4![Southwest logo]()
$288
This Frontier deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Mon 6/18:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/5![Frontier logo]()
$245
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:40 pm
STL
- OMA
Nonstop1h 20m
Southwest
Mon 6/15:40 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 5/5![Southwest logo]()
$269
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/18:08 pm
STL
- OMA
1 stop23h 16m
Frontier
Sat 6/68:19 pm
OMA
- STL
1 stop23h 04m
Frontier
Deal found 5/8![Frontier logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:24 pm
MCI
- OMA
2 stops25h 00m
Frontier
Mon 6/87:56 pm
OMA
- MCI
1 stop17h 04m
Frontier
Deal found 5/4![Frontier logo]()
$232
This Southwest deal was found by Cheapflights users on 5/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:25 am
STL
- OMA
Nonstop1h 20m
Southwest
Wed 6/31:55 pm
OMA
- STL
1 stop9h 20m
Southwest
Deal found 5/7![Southwest logo]()
$275
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/27:42 pm
MCI
- MLI
1 stop4h 32m
American Airlines
Tue 6/94:45 pm
MLI
- MCI
1 stop7h 40m
American Airlines
Deal found 5/5![American Airlines logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:24 pm
MCI
- DSM
2 stops28h 34m
Multiple Airlines
Wed 6/102:16 pm
DSM
- MCI
1 stop22h 44m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$247
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/88:08 pm
STL
- OMA
1 stop23h 22m
Frontier
Mon 6/158:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 5/8![Frontier logo]()
$260
This Delta deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/97:08 am
STL
- DSM
1 stop6h 27m
Delta
Thu 6/115:35 am
DSM
- STL
1 stop6h 59m
Delta
Deal found 5/4![Delta logo]()
$298
This Booking.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/227:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Fri 6/268:15 pm
OMA
- STL
1 stop22h 38m
Frontier
Deal found 5/8![Frontier logo]()
$242
One-way flights from Missouri to IowaSearch for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
Search for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated May 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/4![Frontier logo]()
$65
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/8![Frontier logo]()
$82
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:08 pm
STL
- OMA
1 stop23h 26m
Frontier
Deal found 5/5![Frontier logo]()
$84
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:08 pm
STL
- OMA
1 stop23h 12m
Frontier
Deal found 5/8![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/15:27 pm
STL
- OMA
2 stops25h 57m
Frontier
Deal found 5/4![Frontier logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/175:06 pm
STL
- DSM
2 stops29h 52m
Multiple Airlines
Deal found 5/4![Multiple Airlines logo]()
$115
This Mytrip deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/117:38 pm
STL
- OMA
1 stop23h 52m
Frontier
Deal found 5/8![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/34:19 pm
STL
- OMA
2 stops27h 15m
Frontier
Deal found 5/4![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/105:06 pm
STL
- DSM
2 stops29h 52m
Multiple Airlines
Deal found 5/5![Multiple Airlines logo]()
$131
This Southwest deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:50 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 5/5![Southwest logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/297:03 pm
STL
- DSM
2 stops42h 28m
Frontier
Deal found 5/4![Frontier logo]()
$133
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:03 am
STL
- DSM
1 stop6h 18m
American Airlines
Deal found 5/5![American Airlines logo]()
$140
Find flight deals from Missouri to Iowa
Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated May 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $227 (Mytrip) |
One-way from | $65 (Kiwi.com) |
Popular in | January |
Cheapest in | October |
Average price | $455 |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Kansas CityDes Moines
MCI - DSM
MCIDSM
Kansas City
Wed 6/3
6:24 pm-10:58 pm
2 stops28h 34m
Des Moines
Wed 6/10
2:16 pm-1:00 pm
1 stop22h 44m
$247
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Thu 5/28
8:30 am-9:50 am
Nonstop1h 20m
Omaha Eppley Airfield
Mon 6/1
4:50 pm-11:50 pm
1 stop7h 00m
$279
Kansas CityMoline
MCI - MLI
MCIMLI
Kansas City
Tue 6/2
7:42 pm-12:14 am
1 stop4h 32m
Moline Quad-City
Tue 6/9
4:45 pm-12:25 am
1 stop7h 40m
$279
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Tue 6/2
5:35 am-11:25 am
1 stop5h 50m
Des Moines
Sat 6/6
6:55 pm-11:45 pm
1 stop4h 50m
$288
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Tue 6/9
7:08 am-1:35 pm
1 stop6h 27m
Des Moines
Thu 6/11
5:35 am-12:34 pm
1 stop6h 59m
$298
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 6/10
4:00 pm-9:40 pm
1 stop5h 40m
Des Moines
Sun 6/14
5:10 am-9:30 am
1 stop4h 20m
$305
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Mon 8/10
6:15 pm-10:10 pm
1 stop3h 55m
Des Moines
Thu 8/13
3:50 pm-10:05 pm
1 stop6h 15m
$307
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Thu 6/4
6:30 pm-11:30 pm
1 stop5h 00m
Des Moines
Sun 6/7
5:10 am-9:30 am
1 stop4h 20m
$307
Kansas CityMoline
MCI - MLI
MCIMLI
Kansas City
Tue 5/19
7:49 pm-11:54 pm
1 stop4h 05m
Moline Quad-City
Sat 5/23
6:00 am-1:07 pm
1 stop7h 07m
$309
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Thu 5/28
4:40 pm-11:05 pm
1 stop6h 25m
Des Moines
Fri 5/29
5:25 am-2:55 pm
2 stops9h 30m
$312
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
STL-OMA
STL-DSM
MCI-OMA
MCI-LSE
MCI-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Iowa
USMO-USIA
STL-OMA
STL-DSM
MCI-OMA
MCI-LSE
What is the cheapest time of day to fly from MO to IA?
Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 9, 2026.
When flying from Missouri to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 71% versus a flight in the evening.
How much does it cost to fly round-trip from Missouri to Iowa?
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated May 9, 2026.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Southwest,United Airlines, andAmerican Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Crew
8.6
Entertainment
7.5
Comfort
8.0
Food
7.0
Overall
8.0
Boarding
8.1
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
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Alternative routes for Missouri to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Iowa by cabin class
Find flights from Missouri to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Iowa flights
Browse other Missouri and Iowa flight options. Last updated on May 9, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to Missouri after your stay in Iowa
Missouri to Iowa flights
Consider these flights traveling from Missouri to Iowa.
Top 3 airlines flying from Missouri to Iowa
Discover the top 3 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$316 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$142 | Average$333 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$238 | Average$321 | FlexibilityNo cancel fee | On-time69% |