$110+ Cheap flights from Missouri to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/10. Fares are subject to change and may not be available on all flights or dates of travel.
STL — DSM
Sep 6 — Sep 131
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to IowaExplore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:25 pm -
Nonstop1h 15m
Sat 9/122:15 pm -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$249
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am -
1 stop6h 55m
Wed 8/266:10 am -
2 stops8h 15m
Deal found 8/4![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:05 pm -
2 stops6h 50m
Thu 8/275:40 am -
2 stops9h 40m
Deal found 8/4![Southwest logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:35 am -
2 stops23h 55m
Thu 10/158:41 pm -
1 stop22h 34m
Deal found 8/3![Multiple Airlines logo]()
$257
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:45 pm -
Nonstop1h 15m
Wed 9/24:40 pm -
Nonstop1h 15m
Deal found 8/4![Southwest logo]()
$261
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:55 pm -
Nonstop1h 15m
Sat 9/52:15 pm -
Nonstop1h 20m
Deal found 8/7![Southwest logo]()
$262
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
1 stop5h 34m
Sat 9/126:00 am -
1 stop6h 03m
Deal found 8/6![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am -
Nonstop1h 15m
Mon 8/318:15 am -
Nonstop1h 15m
Deal found 8/2![Southwest logo]()
$269
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:45 pm -
2 stops6h 30m
Thu 9/245:40 am -
1 stop3h 35m
Deal found 8/5![Southwest logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/88:10 pm -
1 stop23h 36m
Thu 10/158:41 pm -
1 stop22h 34m
Deal found 8/3![Frontier logo]()
$283
Best flights from Missouri to IowaDiscover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
Discover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:05 am -
1 stop5h 20m
Mon 8/313:50 pm -
1 stop6h 15m
Deal found 8/2![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
1 stop5h 34m
Sat 9/126:00 am -
1 stop6h 03m
Deal found 8/6![United Airlines logo]()
$264
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:05 am -
1 stop7h 15m
Wed 10/215:35 am -
1 stop5h 15m
Deal found 8/4![Southwest logo]()
$245
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:59 pm -
1 stop4h 26m
Wed 9/21:36 pm -
1 stop5h 40m
Deal found 8/4![United Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:00 am -
1 stop6h 55m
Wed 8/266:10 am -
2 stops8h 15m
Deal found 8/4![Southwest logo]()
$250
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:39 pm -
1 stop4h 29m
Tue 9/86:45 pm -
1 stop5h 50m
Deal found 8/5![American Airlines logo]()
$289
This Delta deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/246:15 am -
1 stop4h 02m
Sun 9/275:59 pm -
1 stop5h 17m
Deal found 8/2![Delta logo]()
$302
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:45 pm -
1 stop6h 10m
Tue 9/82:40 pm -
2 stops7h 35m
Deal found 8/4![Southwest logo]()
$250
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:00 am -
1 stop3h 54m
Wed 9/98:13 am -
1 stop6h 05m
Deal found 8/3![United Airlines logo]()
$289
This American Airlines deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/48:07 pm -
1 stop4h 03m
Sat 9/511:59 am -
1 stop6h 06m
Deal found 8/7![American Airlines logo]()
$300
This KAYAK deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop3h 42m
Wed 9/25:39 pm -
1 stop5h 47m
Deal found 8/3![Delta logo]()
$306
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
Nonstop1h 15m
Sat 9/122:05 pm -
1 stop8h 20m
Deal found 8/6![Southwest logo]()
$259
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/305:08 pm -
1 stop6h 06m
Sun 9/610:30 am -
1 stop5h 37m
Deal found 8/2![United Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:30 am -
Nonstop1h 15m
Wed 9/212:20 pm -
1 stop5h 35m
Deal found 8/4![Southwest logo]()
$271
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:00 am -
1 stop3h 54m
Wed 9/910:42 am -
1 stop5h 30m
Deal found 8/2![United Airlines logo]()
$312
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:55 pm -
Nonstop1h 15m
Sat 9/52:05 pm -
1 stop8h 20m
Deal found 8/7![Southwest logo]()
$272
This United Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:00 am -
1 stop6h 23m
Wed 9/166:00 am -
1 stop5h 57m
Deal found 8/2![United Airlines logo]()
$314
This Alaska Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/21:34 pm -
1 stop24h 50m
Tue 9/83:19 pm -
1 stop8h 40m
Deal found 8/6![Alaska Airlines logo]()
$961
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:30 am -
1 stop6h 39m
Sun 8/238:14 am -
1 stop5h 04m
Deal found 8/4![United Airlines logo]()
$324
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:25 am -
Nonstop1h 15m
Wed 9/164:40 pm -
Nonstop1h 15m
Deal found 8/2![Southwest logo]()
$299
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:46 pm -
1 stop16h 07m
Sun 11/16:49 pm -
1 stop13h 53m
Deal found 8/2![American Airlines logo]()
$482
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/11:40 pm -
2 stops8h 15m
Mon 9/75:40 am -
1 stop3h 35m
Deal found 8/3![Southwest logo]()
$307
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/197:30 am -
1 stop4h 52m
Sun 8/235:40 am -
1 stop5h 08m
Deal found 8/4![United Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/51:08 pm -
1 stop4h 47m
Wed 12/911:13 am -
1 stop4h 28m
Deal found 8/6![United Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:30 am -
1 stop6h 23m
Sun 10/256:55 pm -
1 stop5h 33m
Deal found 8/3![American Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/61:29 pm -
1 stop4h 05m
Sat 10/1011:29 am -
1 stop4h 14m
Deal found 8/3![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/255:30 pm -
1 stop4h 45m
Sun 9/275:40 am -
1 stop5h 05m
Deal found 8/3![Southwest logo]()
$357
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/157:51 pm -
1 stop4h 29m
Fri 9/185:22 pm -
1 stop16h 46m
Deal found 8/5![American Airlines logo]()
$566
Last-minute flights from Missouri to IowaDiscover last-minute flight deals from Missouri to Iowa. Data last updated August 7, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Iowa. Data last updated August 7, 2026 and is based on user searches.
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/253:05 pm -
2 stops6h 50m
Thu 8/275:40 am -
1 stop4h 50m
Deal found 8/4![Southwest logo]()
$250
This Southwest deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:30 am -
Nonstop1h 15m
Mon 8/318:15 am -
Nonstop1h 15m
Deal found 8/2![Southwest logo]()
$269
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/288:07 pm -
1 stop4h 03m
Mon 8/317:44 pm -
1 stop4h 30m
Deal found 8/2![American Airlines logo]()
$284
This Southwest deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:45 pm -
Nonstop1h 15m
Wed 9/24:40 pm -
Nonstop1h 15m
Deal found 8/4![Southwest logo]()
$261
This United Airlines deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/3112:59 pm -
1 stop4h 26m
Wed 9/21:36 pm -
1 stop5h 40m
Deal found 8/4![United Airlines logo]()
$271
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:50 pm -
1 stop5h 09m
Mon 9/76:55 am -
1 stop3h 28m
Deal found 8/4![Delta logo]()
$245
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/17:39 pm -
1 stop4h 29m
Tue 9/86:45 pm -
1 stop5h 50m
Deal found 8/3![American Airlines logo]()
$289
This Southwest deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/42:55 pm -
Nonstop1h 15m
Sat 9/52:15 pm -
Nonstop1h 20m
Deal found 8/7![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:25 pm -
Nonstop1h 15m
Sat 9/122:15 pm -
Nonstop1h 20m
Deal found 8/6![Southwest logo]()
$249
This United Airlines deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/58:30 am -
1 stop5h 34m
Sat 9/126:00 am -
1 stop6h 03m
Deal found 8/6![United Airlines logo]()
$264
This American Airlines deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2111:01 am -
1 stop6h 25m
Thu 9/247:58 pm -
1 stop4h 29m
Deal found 8/5![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/213:45 pm -
2 stops6h 30m
Thu 9/245:40 am -
1 stop3h 35m
Deal found 8/5![Southwest logo]()
$276
One-way flights from Missouri to IowaSearch for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
Search for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated August 7, 2026.
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:01 am -
1 stop6h 25m
Deal found 8/3![American Airlines logo]()
$110
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/103:15 pm -
2 stops7h 00m
Deal found 8/3![Southwest logo]()
$115
This Southwest deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:25 pm -
Nonstop1h 15m
Deal found 8/6![Southwest logo]()
$119
This American Airlines deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop4h 00m
Deal found 8/3![American Airlines logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/810:35 am -
2 stops23h 55m
Deal found 8/6![Multiple Airlines logo]()
$127
This Southwest deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/13:05 pm -
2 stops6h 50m
Deal found 8/3![Southwest logo]()
$128
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/511:13 am -
1 stop5h 44m
Deal found 8/4![Delta logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:10 pm -
1 stop23h 36m
Deal found 8/4![Frontier logo]()
$130
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:30 am -
Nonstop1h 20m
Deal found 8/5![Southwest logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 8/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/28:10 pm -
1 stop22h 24m
Deal found 8/3![Frontier logo]()
$132
This American Airlines deal was found by Cheapflights users on 8/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/227:27 am -
1 stop7h 19m
Deal found 8/2![American Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:35 am -
2 stops48h 05m
Deal found 8/4![Multiple Airlines logo]()
$137
Find flight deals from Missouri to Iowa
Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated August 7, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $219 (American Airlines) |
One-way from | $110 (American Airlines) |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Mon 9/21
11:01 am-5:26 pm
1 stop6h 25m
Des Moines
Thu 9/24
7:58 pm-12:27 am
1 stop4h 29m
$219
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 9/1
3:50 pm-8:59 pm
1 stop5h 09m
Des Moines
Mon 9/7
6:55 am-10:23 am
1 stop3h 28m
$245
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Thu 8/27
6:05 am-11:25 am
1 stop5h 20m
Des Moines
Mon 8/31
3:50 pm-10:05 pm
1 stop6h 15m
$245
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Mon 10/19
6:05 am-1:20 pm
1 stop7h 15m
Des Moines
Wed 10/21
5:35 am-10:50 am
1 stop5h 15m
$245
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 8/25
7:00 am-1:55 pm
1 stop6h 55m
Des Moines
Wed 8/26
6:10 am-2:25 pm
2 stops8h 15m
$250
St. LouisDes Moines
STL Lambert-St Louis - DSM Des Moines
STLDSM
Lambert-St Louis
Tue 9/1
3:45 pm-9:55 pm
1 stop6h 10m
Des Moines
Tue 9/8
2:40 pm-10:15 pm
2 stops7h 35m
$250
St. LouisOmaha
STL Lambert-St Louis - OMA Omaha Eppley Airfield
STLOMA
Lambert-St Louis
Sat 9/5
8:30 am-9:45 am
Nonstop1h 15m
Omaha Eppley Airfield
Sat 9/12
2:05 pm-10:25 pm
1 stop8h 20m
$259
St. LouisOmaha
STL Lambert-St Louis - OMA Omaha Eppley Airfield
STLOMA
Lambert-St Louis
Sat 9/5
8:30 am-2:04 pm
1 stop5h 34m
Omaha Eppley Airfield
Sat 9/12
6:00 am-12:03 pm
1 stop6h 03m
$264
St. LouisOmaha
STL Lambert-St Louis - OMA Omaha Eppley Airfield
STLOMA
Lambert-St Louis
Mon 8/31
12:59 pm-5:25 pm
1 stop4h 26m
Omaha Eppley Airfield
Wed 9/2
1:36 pm-7:16 pm
1 stop5h 40m
$271
St. LouisOmaha
STL Lambert-St Louis - OMA Omaha Eppley Airfield
STLOMA
Lambert-St Louis
Mon 8/31
8:30 am-9:45 am
Nonstop1h 15m
Omaha Eppley Airfield
Wed 9/2
12:20 pm-5:55 pm
1 stop5h 35m
$271
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
STL-DSM
STL-OMA
MCI-MLI
MCI-OMA
JLN-MLI
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Iowa
USMO-USIA
STL-DSM
STL-OMA
MCI-MLI
MCI-OMA
What is the cheapest time of day to fly from MO to IA?
Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 7, 2026.
When flying from Missouri to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 71% versus a flight in the evening.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated August 7, 2026.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Southwest and United Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Overall
8.0
Boarding
8.1
Food
7.0
Entertainment
7.5
Comfort
8.0
Crew
8.6
Reviews
1 / 20
8.0
ExcellentLibby,Jun 2026
TUS - LAS
Related info for your journey
Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Iowa by cabin class
Find flights from Missouri to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Iowa flights
Browse other Missouri and Iowa flight options. Last updated on August 7, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to Missouri after your stay in Iowa
Missouri to Iowa flights
Consider these flights traveling from Missouri to Iowa.
Top 2 airlines flying from Missouri to Iowa
Discover the top 2 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$371 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$218 | Average$408 | FlexibilityNo cancel fee | On-time69% |