$123+ Cheap flights from Missouri to Iowa
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/20. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — DSM
Jul 25 — Aug 11
Round-trip
1 adult, Economy
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Cheapest flights from Missouri to IowaExplore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
Explore the most affordable flight options available from Missouri to Iowa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:57 pm
STL
- DSM
2 stops30h 10m
Multiple Airlines
Wed 7/291:49 pm
DSM
- STL
1 stop28h 26m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$247
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Thu 7/168:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/22![Frontier logo]()
$261
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Wed 7/225:20 am
DSM
- STL
1 stop5h 55m
Southwest
Deal found 6/21![Southwest logo]()
$263
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Tue 7/285:20 am
DSM
- STL
2 stops9h 25m
Southwest
Deal found 6/23![Southwest logo]()
$268
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:15 am
STL
- DSM
2 stops11h 40m
Southwest
Wed 8/266:10 am
DSM
- STL
2 stops8h 15m
Southwest
Deal found 6/24![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:20 pm
STL
- OMA
Nonstop1h 20m
Southwest
Wed 7/295:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/24![Southwest logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:10 pm
STL
- OMA
1 stop16h 06m
Multiple Airlines
Tue 7/218:15 pm
OMA
- STL
1 stop23h 08m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:15 am
STL
- DSM
2 stops12h 35m
Southwest
Wed 7/295:20 am
DSM
- STL
2 stops9h 25m
Southwest
Deal found 6/21![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:30 am
MCI
- MLI
1 stop5h 53m
American Airlines
Wed 7/296:50 pm
MLI
- MCI
1 stop5h 29m
American Airlines
Deal found 6/24![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:00 pm
STL
- DSM
1 stop5h 35m
Southwest
Mon 10/54:30 pm
DSM
- STL
2 stops7h 10m
Southwest
Deal found 6/23![Southwest logo]()
$284
This Southwest deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:05 am
STL
- DSM
1 stop5h 20m
Southwest
Sun 9/67:05 am
DSM
- STL
1 stop5h 20m
Southwest
Deal found 6/22![Southwest logo]()
$286
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Mon 7/138:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/22![Frontier logo]()
$292
Best flights from Missouri to IowaDiscover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
Discover carefully curated flight deals from Missouri to Iowa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 25, 2026.
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:40 am
STL
- DSM
1 stop5h 50m
Southwest
Wed 7/295:20 am
DSM
- STL
1 stop5h 55m
Southwest
Deal found 6/21![Southwest logo]()
$263
This United Airlines deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:00 am
STL
- DSM
1 stop4h 17m
United Airlines
Wed 7/296:00 am
DSM
- STL
1 stop6h 11m
United Airlines
Deal found 6/23![United Airlines logo]()
$263
This American Airlines deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:58 pm
STL
- DSM
1 stop6h 03m
American Airlines
Sat 8/16:18 pm
DSM
- STL
1 stop5h 57m
American Airlines
Deal found 6/20![American Airlines logo]()
$263
This Delta deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/85:34 pm
STL
- OMA
1 stop5h 24m
Delta
Sun 8/96:10 am
OMA
- STL
1 stop4h 13m
Delta
Deal found 6/22![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/191:45 pm
MCI
- OMA
1 stop5h 30m
Frontier
Sun 7/268:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Deal found 6/20![Frontier logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/234:32 pm
MCI
- OMA
1 stop18h 44m
Multiple Airlines
Sun 7/268:00 pm
OMA
- MCI
1 stop17h 00m
Multiple Airlines
Deal found 6/23![Multiple Airlines logo]()
$439
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:40 am
STL
- DSM
1 stop5h 50m
Southwest
Tue 7/285:20 am
DSM
- STL
1 stop4h 15m
Southwest
Deal found 6/23![Southwest logo]()
$263
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:30 am
MCI
- MLI
1 stop5h 53m
American Airlines
Wed 7/296:50 pm
MLI
- MCI
1 stop5h 29m
American Airlines
Deal found 6/24![American Airlines logo]()
$279
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:15 am
STL
- DSM
2 stops11h 40m
Southwest
Wed 8/266:10 am
DSM
- STL
2 stops8h 15m
Southwest
Deal found 6/24![Southwest logo]()
$273
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:20 pm
STL
- OMA
Nonstop1h 20m
Southwest
Wed 7/295:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/24![Southwest logo]()
$275
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/121:45 pm
MCI
- MLI
1 stop7h 18m
United Airlines
Tue 12/1510:35 am
MLI
- MCI
1 stop3h 56m
United Airlines
Deal found 6/24![United Airlines logo]()
$349
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:40 am
STL
- DSM
1 stop5h 40m
Southwest
Mon 10/55:35 am
DSM
- STL
1 stop3h 15m
Southwest
Deal found 6/23![Southwest logo]()
$279
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:02 am
JLN
- MLI
1 stop6h 56m
United Airlines
Tue 11/178:20 am
MLI
- JLN
1 stop4h 02m
United Airlines
Deal found 6/22![United Airlines logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:07 pm
MCI
- OMA
2 stops25h 08m
Frontier
Sat 7/258:00 pm
OMA
- MCI
1 stop17h 00m
Frontier
Deal found 6/20![Frontier logo]()
$407
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:00 am
STL
- OMA
1 stop4h 20m
United Airlines
Wed 8/263:11 pm
OMA
- STL
1 stop6h 49m
United Airlines
Deal found 6/22![United Airlines logo]()
$355
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Thu 7/235:10 am
DSM
- STL
1 stop4h 00m
Southwest
Deal found 6/23![Southwest logo]()
$304
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:59 pm
STL
- FOD
1 stop4h 53m
United Airlines
Wed 9/211:19 am
FOD
- STL
1 stop4h 19m
United Airlines
Deal found 6/21![United Airlines logo]()
$369
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2910:15 am
STL
- DSM
2 stops12h 35m
Southwest
Sat 8/16:55 pm
DSM
- STL
1 stop4h 55m
Southwest
Deal found 6/20![Southwest logo]()
$314
This United Airlines deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:37 pm
MCI
- MLI
1 stop5h 39m
United Airlines
Tue 7/143:47 pm
MLI
- MCI
1 stop6h 07m
United Airlines
Deal found 6/25![United Airlines logo]()
$379
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1112:19 pm
MCI
- LSE
1 stop4h 33m
American Airlines
Sun 9/135:22 pm
LSE
- MCI
1 stop7h 01m
American Airlines
Deal found 6/21![American Airlines logo]()
$512
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:45 pm
STL
- OMA
Nonstop1h 15m
Southwest
Mon 8/104:50 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/20![Southwest logo]()
$340
This United Airlines deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/97:53 am
MCI
- MLI
1 stop6h 03m
United Airlines
Mon 7/131:15 pm
MLI
- MCI
1 stop4h 21m
United Airlines
Deal found 6/22![United Airlines logo]()
$379
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/268:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Sun 9/278:00 am
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/21![Southwest logo]()
$344
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/96:34 pm
SGF
- MLI
1 stop4h 42m
United Airlines
Mon 7/136:30 pm
MLI
- SGF
1 stop4h 57m
United Airlines
Deal found 6/24![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/19:50 am
MCI
- DSM
1 stop4h 05m
Southwest
Thu 9/32:25 pm
DSM
- MCI
1 stop7h 00m
Southwest
Deal found 6/20![Southwest logo]()
$347
This American Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/67:53 pm
SGF
- MLI
1 stop4h 48m
American Airlines
Fri 7/104:20 pm
MLI
- SGF
1 stop5h 14m
American Airlines
Deal found 6/21![American Airlines logo]()
$668
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/266:30 am
MCI
- DSM
1 stop4h 55m
Southwest
Fri 8/73:50 pm
DSM
- MCI
1 stop6h 15m
Southwest
Deal found 6/24![Southwest logo]()
$347
This United Airlines deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/87:30 am
MCI
- MLI
1 stop5h 07m
United Airlines
Sun 10/116:32 am
MLI
- MCI
1 stop3h 54m
United Airlines
Deal found 6/21![United Airlines logo]()
$446
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/243:45 pm
MCI
- DSM
1 stop6h 25m
Southwest
Sun 9/275:40 am
DSM
- MCI
1 stop4h 00m
Southwest
Deal found 6/21![Southwest logo]()
$347
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/265:30 pm
MCI
- DSM
2 stops6h 20m
Southwest
Thu 8/65:40 am
DSM
- MCI
1 stop5h 40m
Southwest
Deal found 6/23![Southwest logo]()
$352
Last-minute flights from Missouri to IowaDiscover last-minute flight deals from Missouri to Iowa. Data last updated June 25, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Iowa. Data last updated June 25, 2026 and is based on user searches.
This Trip.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/68:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Wed 7/88:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/21![Frontier logo]()
$301
This Trip.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/108:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Tue 7/148:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/25![Frontier logo]()
$302
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Mon 7/138:00 pm
OMA
- STL
1 stop23h 23m
Frontier
Deal found 6/22![Frontier logo]()
$292
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Thu 7/168:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/22![Frontier logo]()
$261
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/148:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Tue 7/218:15 pm
OMA
- STL
1 stop23h 08m
Frontier
Deal found 6/22![Frontier logo]()
$297
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/155:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Wed 7/225:20 am
DSM
- STL
1 stop5h 55m
Southwest
Deal found 6/21![Southwest logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:10 pm
STL
- OMA
1 stop16h 06m
Multiple Airlines
Tue 7/218:15 pm
OMA
- STL
1 stop23h 08m
Multiple Airlines
Deal found 6/22![Multiple Airlines logo]()
$278
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/215:55 pm
STL
- DSM
1 stop4h 55m
Southwest
Tue 7/285:20 am
DSM
- STL
2 stops9h 25m
Southwest
Deal found 6/23![Southwest logo]()
$268
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/224:57 pm
STL
- DSM
2 stops30h 10m
Multiple Airlines
Wed 7/291:49 pm
DSM
- STL
1 stop28h 26m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$247
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/229:20 pm
STL
- OMA
Nonstop1h 20m
Southwest
Wed 7/295:10 pm
OMA
- STL
Nonstop1h 15m
Southwest
Deal found 6/24![Southwest logo]()
$275
This Southwest deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2210:15 am
STL
- DSM
2 stops12h 35m
Southwest
Wed 7/295:20 am
DSM
- STL
2 stops9h 25m
Southwest
Deal found 6/21![Southwest logo]()
$279
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/225:30 am
MCI
- MLI
1 stop5h 53m
American Airlines
Wed 7/296:50 pm
MLI
- MCI
1 stop5h 29m
American Airlines
Deal found 6/24![American Airlines logo]()
$279
One-way flights from Missouri to IowaSearch for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
Search for one-way flight options from Missouri to Iowa. Find affordable one-way fares based on user searches. Data last updated June 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 pm
STL
- OMA
1 stop25h 31m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$123
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/298:08 pm
STL
- OMA
1 stop23h 07m
Frontier
Deal found 6/22![Frontier logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/167:10 pm
STL
- OMA
1 stop16h 06m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$130
This United Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:00 am
STL
- DSM
1 stop4h 17m
United Airlines
Deal found 6/24![United Airlines logo]()
$132
This Booking.com deal was found by Cheapflights users on 6/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/138:10 pm
STL
- DSM
1 stop17h 46m
Frontier
Deal found 6/22![Frontier logo]()
$134
This Southwest deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:45 pm
STL
- DSM
2 stops8h 05m
Southwest
Deal found 6/24![Southwest logo]()
$137
This Southwest deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/188:45 pm
STL
- OMA
Nonstop1h 20m
Southwest
Deal found 6/20![Southwest logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:10 pm
STL
- OMA
1 stop16h 06m
Multiple Airlines
Deal found 6/21![Multiple Airlines logo]()
$142
This Delta deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/186:20 am
STL
- OMA
1 stop5h 40m
Delta
Deal found 6/23![Delta logo]()
$143
This Southwest deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:30 am
STL
- OMA
Nonstop1h 15m
Southwest
Deal found 6/23![Southwest logo]()
$145
This American Airlines deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:16 am
STL
- OMA
1 stop6h 09m
American Airlines
Deal found 6/24![American Airlines logo]()
$147
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/184:57 pm
STL
- DSM
2 stops29h 50m
Multiple Airlines
Deal found 6/24![Multiple Airlines logo]()
$148
Find flight deals from Missouri to Iowa
Keep the following information in mind while searching for Missouri to Iowa flight deals. Data was last updated June 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $247 (Kiwi.com) |
One-way from | $123 (Kiwi.com) |
Popular in | February |
Cheapest in | October |
Average price | $371 |
Good one-way deal | $194 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Iowa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Missouri to Iowa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 7/22
5:40 am-11:30 am
1 stop5h 50m
Des Moines
Wed 7/29
5:20 am-11:15 am
1 stop5h 55m
$263
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 7/22
6:00 am-10:17 am
1 stop4h 17m
Des Moines
Wed 7/29
6:00 am-12:11 pm
1 stop6h 11m
$263
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 7/29
5:58 pm-12:01 am
1 stop6h 03m
Des Moines
Sat 8/1
6:18 pm-12:15 am
1 stop5h 57m
$263
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Tue 7/21
5:40 am-11:30 am
1 stop5h 50m
Des Moines
Tue 7/28
5:20 am-9:35 am
1 stop4h 15m
$263
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Tue 8/25
10:15 am-9:55 pm
2 stops11h 40m
Des Moines
Wed 8/26
6:10 am-2:25 pm
2 stops8h 15m
$273
St. LouisOmaha
STL - OMA
STLOMA
Lambert-St Louis
Wed 7/22
9:20 pm-10:40 pm
Nonstop1h 20m
Omaha Eppley Airfield
Wed 7/29
5:10 pm-6:25 pm
Nonstop1h 15m
$275
Kansas CityMoline
MCI - MLI
MCIMLI
Kansas City
Wed 7/22
5:30 am-11:23 am
1 stop5h 53m
Moline Quad-City
Wed 7/29
6:50 pm-12:19 am
1 stop5h 29m
$279
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Thu 10/1
5:40 am-11:20 am
1 stop5h 40m
Des Moines
Mon 10/5
5:35 am-8:50 am
1 stop3h 15m
$279
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 7/22
5:55 pm-10:50 pm
1 stop4h 55m
Des Moines
Thu 7/23
5:10 am-9:10 am
1 stop4h 00m
$304
St. LouisDes Moines
STL - DSM
STLDSM
Lambert-St Louis
Wed 7/29
10:15 am-10:50 pm
2 stops12h 35m
Des Moines
Sat 8/1
6:55 pm-11:50 pm
1 stop4h 55m
$314
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Iowa
Have a flexible travel schedule? Discover the best time to fly to Iowa from Missouri with our price prediction graph.
STL-OMA
STL-DSM
MCI-MLI
MCI-OMA
MCI-DSM
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Iowa
USMO-USIA
STL-OMA
STL-DSM
MCI-MLI
MCI-OMA
What is the cheapest time of day to fly from MO to IA?
Find hourly flight availability from Missouri to Iowa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 25, 2026.
When flying from Missouri to Iowa, the time of day you fly usually plays a role in the price. Save by searching for a flight in the afternoon, which can drop the price by up to 71% versus a flight in the evening.
Reviews of airlines servicing Iowa
Get insights into the airlines that provide service to Iowa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Iowa. Reviews last updated June 25, 2026.
Read through reviews of airlines operating flights from Missouri to Iowa, such as Southwest and American Airlines. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Comfort
8.0
Food
7.0
Overall
7.9
Boarding
8.1
Crew
8.6
Entertainment
7.5
Reviews
1 / 20
6.0
GoodReza,Jun 2026
TPA - MDW
Related info for your journey
Find useful and relevant information for your journey from Missouri to Iowa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Iowa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Iowa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Iowa by cabin class
Find flights from Missouri to Iowa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Iowa flights
Browse other Missouri and Iowa flight options. Last updated on June 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Iowa
Find the right flight back to Missouri after your stay in Iowa
Missouri to Iowa flights
Consider these flights traveling from Missouri to Iowa.
Top 2 airlines flying from Missouri to Iowa
Discover the top 2 airlines that operate flights from Missouri to Iowa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$77 | Average$316 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$142 | Average$338 | FlexibilityNo cancel fee | On-time71% |