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$75+ Cheap flights from South Carolina to Mississippi

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/29. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — JAN
Dec 1 — Dec 81
Mon 12/1
Mon 12/8
1 adult, Economy
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Find flight deals from South Carolina to Mississippi

Cheapest flights from South Carolina to Mississippi
Explore the most affordable flight options available from South Carolina to Mississippi. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 1, 2025.

This Booking.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/103:50 pmCLT - MEM
1 stop5h 10mMultiple Airlines
Thu 11/138:10 pmMEM - CLT
1 stop20h 07mMultiple Airlines
Deal found 10/30$191
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:56 amCLT - MEM
1 stop22h 06mMultiple Airlines
Tue 11/2510:07 amMEM - CLT
1 stop21h 09mMultiple Airlines
Deal found 10/30$199
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:59 pmCLT - MEM
1 stop23h 37mMultiple Airlines
Mon 12/87:42 pmMEM - CLT
2 stops27h 17mMultiple Airlines
Deal found 10/30$201
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/33:56 pmCLT - MEM
1 stop27h 51mSpirit Airlines
Mon 12/87:42 pmMEM - CLT
2 stops27h 17mSpirit Airlines
Deal found 10/30$204
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:00 pmGSP - MEM
1 stop23h 26mAllegiant Air
Mon 12/153:16 pmMEM - GSP
1 stop24h 32mAllegiant Air
Deal found 10/31$210
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/206:09 pmCLT - MEM
1 stop21h 25mMultiple Airlines
Tue 11/2510:07 amMEM - CLT
1 stop21h 09mMultiple Airlines
Deal found 10/30$216
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/164:30 pmCAE - MEM
1 stop26h 26mMultiple Airlines
Thu 11/2010:58 amMEM - CAE
1 stop9h 06mMultiple Airlines
Deal found 10/29$216
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/2111:56 amCLT - MEM
1 stop22h 06mMultiple Airlines
Mon 11/2412:37 pmMEM - CLT
1 stop18h 39mMultiple Airlines
Deal found 10/30$223
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/243:33 pmCHS - MEM
1 stop18h 29mMultiple Airlines
Thu 11/2711:20 amMEM - CHS
1 stop9h 45mMultiple Airlines
Deal found 10/29$224
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/510:33 pmCLT - MEM
1 stop21h 14mMultiple Airlines
Mon 12/87:42 pmMEM - CLT
1 stop13h 08mMultiple Airlines
Deal found 10/31$228
This Kiwi.com deal was found by Cheapflights users on 10/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:47 amCLT - GPT
1 stop9h 28mMultiple Airlines
Sun 11/237:55 pmGPT - CLT
1 stop16h 51mMultiple Airlines
Deal found 10/29$230
This Kiwi.com deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/57:00 amCLT - MEM
2 stops12h 47mMultiple Airlines
Sun 12/75:14 pmMEM - CLT
1 stop15h 25mMultiple Airlines
Deal found 10/28$232

Cheap flight deals from South Carolina to Mississippi

Keep the following information in mind while searching for South Carolina to Mississippi flight deals. Data was last updated November 1, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$191
(Booking.com)

One-way from

$75
(Frontier)
Provider with most accurate pricing for Myrtle Beach Intl-Jackson-Evers Intl flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Jackson-Evers Intl flights.
Search Deals
From South Carolina to Mississippi
Search Deals
One-way flight from South Carolina to Mississippi
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Mississippi that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 1, 2025.
Use the filters below to find and compare flights from South Carolina to Mississippi that are best for you.

Fly from

South Carolina

Fly to

Mississippi

Route

Depart

Return

Price

ColumbiaMemphis

CAE - MEM

CAEMEM

Columbia Metropolitan

Sun 11/16

4:30 pm-5:56 pm

1 stop26h 26m

Memphis

Thu 11/20

10:58 am-9:04 pm

1 stop9h 06m

$216

CharlestonMemphis

CHS - MEM

CHSMEM

Charleston

Mon 11/24

3:33 pm-9:02 am

1 stop18h 29m

Memphis

Thu 11/27

11:20 am-10:05 pm

1 stop9h 45m

$224

CharlotteMemphis

CLT - MEM

CLTMEM

Charlotte Douglas

Fri 12/5

10:33 pm-6:47 pm

1 stop21h 14m

Memphis

Mon 12/8

7:42 pm-9:50 am

1 stop13h 08m

$228

CharlotteMemphis

CLT - MEM

CLTMEM

Charlotte Douglas

Mon 2/23

8:52 am-3:14 pm

1 stop7h 22m

Memphis

Thu 2/26

2:51 pm-11:55 am

1 stop20h 04m

$230

CharlotteGulfport

CLT - GPT

CLTGPT

Charlotte Douglas

Thu 11/13

2:45 pm-7:15 pm

1 stop5h 30m

Gulfport Biloxi Regional

Sun 11/16

7:55 pm-9:02 am

1 stop12h 07m

$235

CharlotteMemphis

CLT - MEM

CLTMEM

Charlotte Douglas

Thu 11/13

6:07 pm-11:28 am

2 stops18h 21m

Memphis

Mon 11/17

8:55 pm-1:32 pm

1 stop15h 37m

$238

CharlestonMemphis

CHS - MEM

CHSMEM

Charleston

Fri 12/5

9:49 pm-6:47 pm

2 stops21h 58m

Memphis

Sun 12/7

7:42 pm-8:54 pm

2 stops24h 12m

$246

CharlotteMemphis

CLT - MEM

CLTMEM

Charlotte Douglas

Thu 11/20

6:09 pm-2:34 pm

1 stop21h 25m

Memphis

Mon 11/24

5:48 pm-4:50 pm

2 stops22h 02m

$253

ColumbiaMemphis

CAE - MEM

CAEMEM

Columbia Metropolitan

Sat 2/21

8:45 am-12:43 pm

1 stop4h 58m

Memphis

Tue 2/24

12:00 pm-5:58 pm

1 stop4h 58m

$271

CharlotteMemphis

CLT - MEM

CLTMEM

Charlotte Douglas

Mon 11/17

3:50 pm-8:00 pm

1 stop5h 10m

Memphis

Thu 11/20

10:58 am-7:57 pm

1 stop7h 59m

$271

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/31

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Mississippi

Have a flexible travel schedule? Discover the best time to fly to Mississippi from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Mississippi

What is the cheapest month to book a flight from South Carolina to Mississippi?

Currently, April is the cheapest month in which you can book a flight from South Carolina to Mississippi (average of $165). Flying from South Carolina to Mississippi in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MS?

Find hourly flight availability from South Carolina to Mississippi. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 1, 2025.

It’s typically best to fly out from South Carolina to Mississippi at noon. Doing so could potentially save you 39% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from South Carolina to Mississippi?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Mississippi. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Mississippi flight should consider departing on Sunday mornings when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Reviews of airlines servicing Mississippi

Get insights into the airlines that provide service to Mississippi. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mississippi. Reviews last updated November 1, 2025.
Peruse reviews from past customers who have flown with Delta and American Airlines from South Carolina to Mississippi to help guide your decision. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,996 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
Delta
7.9
Good
7,996 reviews
Delta
7.9
Good
7,996 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.
American Airlines
7.2
Good
11,031 reviews
Delta
7.9
Good
7,996 reviews

Crew

8.5

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Comfort

7.9

Reviews

1 / 20
8.0
Excellent

Matthew,Oct 2025

GSP - ATL

This is always a full flight since it is the connecting route to primary destinations through Atlanta. That said, the crew handles the full load well. Not much more to say, it is a short flight with no in-flight services due to the length.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Mississippi. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Mississippi?

    For as low as $288, Spirit Airlines can have you in Mississippi from South Carolina in 4h 50m. Airlines will cover a distance of 439 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from South Carolina to Mississippi one-way?

    For one-way options, check prices for Frontier. According to our data, you can fly for as low as $89. Users have also found prices from $105 and $115 on Allegiant Air and Spirit Airlines, respectively.

  • Can I find deals for flights from South Carolina to Mississippi that include hotel bookings?

    Yes. In addition to deals on South Carolina to Mississippi flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Mississippi?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Mississippi.

  • Can I find deals for business class flights from South Carolina to Mississippi?

    Yes. Cheapflights offers flight deals from South Carolina to Mississippi by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Mississippi?

    Currently, April is the cheapest month in which you can book a flight from South Carolina to Mississippi (average of $165). Flying from South Carolina to Mississippi in March is currently the most expensive (average of $303). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Mississippi

See prices for flight routes from nearby airports that may be better suited for you.
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Top 2 airlines flying from South Carolina to Mississippi

Discover the top 2 airlines that operate flights from South Carolina to Mississippi. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 1, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$207Average$389FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$237Average$405FlexibilityNo cancel feeOn-time71%

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