$173+ Cheap flights from Florence, SC (FLO) to Michigan
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/3. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
May 1 — May 81
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Florence to Michigan with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Florence to Michigan
Cheapest
Best
Last-minute
One-way
Cheapest flights from Florence to MichiganExplore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 1, 2026.
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:02 pm
FLO
- ORD
1 stop4h 20m
American Airlines
Tue 5/54:17 pm
ORD
- FLO
1 stop5h 25m
American Airlines
Deal found 3/31![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:20 am
FLO
- DTW
1 stop5h 57m
American Airlines
Wed 5/2710:01 am
DTW
- FLO
1 stop4h 09m
American Airlines
Deal found 4/1![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
FLO
- ORD
1 stop4h 56m
American Airlines
Sat 4/181:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 3/30![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Fri 5/84:17 pm
ORD
- FLO
1 stop4h 30m
American Airlines
Deal found 4/1![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/316:15 am
FLO
- ORD
1 stop7h 20m
American Airlines
Sun 4/510:28 am
ORD
- FLO
1 stop6h 22m
American Airlines
Deal found 3/30![American Airlines logo]()
$376
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
FLO
- DTW
1 stop4h 17m
American Airlines
Sat 4/1810:11 am
DTW
- FLO
1 stop5h 39m
American Airlines
Deal found 3/30![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
FLO
- ORD
1 stop5h 54m
American Airlines
Mon 4/278:39 am
ORD
- FLO
1 stop6h 11m
American Airlines
Deal found 3/30![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Mon 4/201:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 4/1![American Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:17 am
FLO
- DTW
1 stop4h 00m
American Airlines
Sun 7/1210:01 am
DTW
- FLO
1 stop4h 09m
American Airlines
Deal found 3/29![American Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:16 pm
FLO
- DTW
1 stop6h 12m
American Airlines
Fri 4/1710:11 am
DTW
- FLO
1 stop5h 39m
American Airlines
Deal found 3/29![American Airlines logo]()
$935
Best flights from Florence to MichiganDiscover carefully curated flight deals from Florence to Michigan that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
Discover carefully curated flight deals from Florence to Michigan that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 1, 2026.
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:02 pm
FLO
- ORD
1 stop4h 20m
American Airlines
Tue 5/54:17 pm
ORD
- FLO
1 stop5h 25m
American Airlines
Deal found 3/31![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:20 am
FLO
- DTW
1 stop4h 07m
American Airlines
Wed 5/276:40 am
DTW
- FLO
2 stops7h 30m
American Airlines
Deal found 4/1![American Airlines logo]()
$330
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
FLO
- ORD
1 stop4h 56m
American Airlines
Sat 4/181:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 3/30![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:02 pm
FLO
- DTW
2 stops6h 14m
American Airlines
Sat 4/187:01 am
DTW
- FLO
2 stops8h 49m
American Airlines
Deal found 3/30![American Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Mon 4/201:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 4/1![American Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Fri 5/81:25 pm
ORD
- FLO
2 stops7h 22m
American Airlines
Deal found 4/1![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/95:17 am
FLO
- DTW
1 stop4h 00m
American Airlines
Sun 7/1210:01 am
DTW
- FLO
1 stop4h 09m
American Airlines
Deal found 3/29![American Airlines logo]()
$637
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
FLO
- ORD
1 stop5h 54m
American Airlines
Mon 4/271:25 pm
ORD
- FLO
2 stops7h 22m
American Airlines
Deal found 3/30![American Airlines logo]()
$668
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:16 pm
FLO
- DTW
2 stops6h 00m
American Airlines
Fri 4/1711:57 am
DTW
- FLO
1 stop3h 53m
American Airlines
Deal found 3/29![American Airlines logo]()
$940
Last-minute flights from Florence to MichiganDiscover last-minute flight deals from Florence to Michigan. Data last updated April 1, 2026 and is based on user searches.
Discover last-minute flight deals from Florence to Michigan. Data last updated April 1, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/134:16 pm
FLO
- DTW
1 stop6h 12m
American Airlines
Fri 4/1710:11 am
DTW
- FLO
1 stop5h 39m
American Airlines
Deal found 3/29![American Airlines logo]()
$935
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
FLO
- ORD
1 stop4h 56m
American Airlines
Sat 4/181:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 3/30![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:15 am
FLO
- DTW
1 stop4h 17m
American Airlines
Sat 4/1810:11 am
DTW
- FLO
1 stop5h 39m
American Airlines
Deal found 3/30![American Airlines logo]()
$395
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/165:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Mon 4/201:54 pm
ORD
- FLO
1 stop6h 53m
American Airlines
Deal found 4/1![American Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/245:20 am
FLO
- ORD
1 stop5h 54m
American Airlines
Mon 4/278:39 am
ORD
- FLO
1 stop6h 11m
American Airlines
Deal found 3/30![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/284:02 pm
FLO
- ORD
1 stop4h 20m
American Airlines
Tue 5/54:17 pm
ORD
- FLO
1 stop5h 25m
American Airlines
Deal found 3/31![American Airlines logo]()
$309
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:20 am
FLO
- ORD
1 stop5h 51m
American Airlines
Fri 5/84:17 pm
ORD
- FLO
1 stop4h 30m
American Airlines
Deal found 4/1![American Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:20 am
FLO
- DTW
1 stop5h 57m
American Airlines
Wed 5/2710:01 am
DTW
- FLO
1 stop4h 09m
American Airlines
Deal found 4/1![American Airlines logo]()
$324
One-way flights from Florence to MichiganSearch for one-way flight options from Florence to Michigan. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
Search for one-way flight options from Florence to Michigan. Find affordable one-way fares based on user searches. Data last updated April 1, 2026.
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/32:35 pm
FLO
- ORD
1 stop6h 13m
American Airlines
Deal found 4/1![American Airlines logo]()
$173
This American Airlines deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/305:20 am
FLO
- DTW
2 stops11h 42m
American Airlines
Deal found 3/31![American Airlines logo]()
$326
Find flight deals from Florence to Michigan
Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated April 1, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $309 (American Airlines) |
One-way from | $173 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 1, 2026.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
FlorenceChicago
FLO - ORD
FLOORD
Florence
Tue 4/28
4:02 pm-7:22 pm
1 stop4h 20m
Chicago O'Hare Intl
Tue 5/5
4:17 pm-10:42 pm
1 stop5h 25m
$309
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Wed 5/20
5:20 am-9:27 am
1 stop4h 07m
Detroit Metropolitan Wayne County
Wed 5/27
6:40 am-2:10 pm
2 stops7h 30m
$330
FlorenceChicago
FLO - ORD
FLOORD
Florence
Tue 4/14
6:15 am-10:11 am
1 stop4h 56m
Chicago O'Hare Intl
Sat 4/18
1:54 pm-9:47 pm
1 stop6h 53m
$339
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Tue 4/14
4:02 pm-10:16 pm
2 stops6h 14m
Detroit Metropolitan Wayne County
Sat 4/18
7:01 am-3:50 pm
2 stops8h 49m
$405
FlorenceChicago
FLO - ORD
FLOORD
Florence
Thu 4/16
5:20 am-10:11 am
1 stop5h 51m
Chicago O'Hare Intl
Mon 4/20
1:54 pm-9:47 pm
1 stop6h 53m
$431
FlorenceChicago
FLO - ORD
FLOORD
Florence
Fri 5/1
5:20 am-10:11 am
1 stop5h 51m
Chicago O'Hare Intl
Fri 5/8
1:25 pm-9:47 pm
2 stops7h 22m
$634
Quickest round-trip
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Thu 7/9
5:17 am-9:17 am
1 stop4h 00m
Detroit Metropolitan Wayne County
Sun 7/12
10:01 am-2:10 pm
1 stop4h 09m
$637
FlorenceChicago
FLO - ORD
FLOORD
Florence
Fri 4/24
5:20 am-10:14 am
1 stop5h 54m
Chicago O'Hare Intl
Mon 4/27
1:25 pm-9:47 pm
2 stops7h 22m
$668
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Mon 4/13
4:16 pm-10:16 pm
2 stops6h 00m
Detroit Metropolitan Wayne County
Fri 4/17
11:57 am-3:50 pm
1 stop3h 53m
$940
Cheapest one-way
Quickest one-way
FlorenceChicago
FLO - ORD
FLOORD
Florence
Wed 6/3
2:35 pm-7:48 pm
1 stop6h 13m
$173
Showing 1-10 of 11 resultsSorted by cheapest first
Best time to book a flight from Florence to Michigan
Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
FLO-ORD
FLO-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Michigan
FLO-USMI
FLO-ORD
FLO-DTW
What is the cheapest month to book a flight from Florence, South Carolina to Michigan?
Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in March is currently the most expensive (average of $168). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from Florence to Michigan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Top destinations