$263+ Cheap flights from Florence, SC (FLO) to Michigan
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/21. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Jan 17 — Jan 241
1 adult, Economy
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1. Tell us where you want to go
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Cheapest flights from Florence to MichiganExplore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/2212:51 pmFLO - DTW
1 stop3h 35mAmerican Airlines
Wed 12/3111:56 amDTW - FLO
1 stop6h 09mAmerican Airlines
Deal found 12/15![American Airlines logo]()
$362
Find flight deals from Florence to Michigan
Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated December 18, 2025.
Most accurate provider | eDreams 3 stars |
|---|---|
Most trusted provider | eDreams 3 stars |
Round-trip from | $263 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.
Fly from
Florence
Fly to
Michigan
Route
Depart
Return
Price
FlorenceDetroit
FLO - DTW
FLODTW
Florence
Wed 1/21
5:36 pm-10:30 pm
1 stop4h 54m
Detroit Metropolitan Wayne County
Tue 1/27
6:17 pm-10:43 pm
1 stop4h 26m
$263
FlorenceChicago
FLO - ORD
FLOORD
Florence
Thu 1/1
5:15 am-10:45 am
1 stop6h 30m
Chicago O'Hare Intl
Mon 1/5
6:37 pm-12:15 am
1 stop4h 38m
$443
Best time to book a flight from Florence to Michigan
Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florence to Michigan
What is the cheapest month to book a flight from Florence, South Carolina to Michigan?
Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in December is currently the most expensive (average of $150). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.