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$404+ Cheap flights from Florence, SC (FLO) to Michigan

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/11. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Florence to Michigan

Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated September 17, 2025.

Round-trip from

$404
(American Airlines)
From Florence to Michigan
Search Deals

Find flight deals from Florence to Michigan

Cheapest flights from Florence to Michigan
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/115:14 amFLO - ORD
1 stop5h 15mAmerican Airlines
Sat 10/184:56 pmORD - FLO
1 stop6h 07mAmerican Airlines
Deal found 9/17$404
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/76:14 amFLO - ORD
1 stop4h 16mAmerican Airlines
Tue 10/147:10 amORD - FLO
1 stop6h 44mAmerican Airlines
Deal found 9/17$426
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/15:37 pmFLO - ORD
1 stop6h 35mAmerican Airlines
Sun 10/58:38 amORD - FLO
1 stop6h 54mAmerican Airlines
Deal found 9/15$437
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/2511:11 amFLO - ORD
1 stop4h 03mAmerican Airlines
Mon 12/15:00 amORD - FLO
1 stop4h 45mAmerican Airlines
Deal found 9/16$444
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/25:14 amFLO - ORD
2 stops7h 48mAmerican Airlines
Mon 10/65:00 amORD - FLO
2 stops8h 04mAmerican Airlines
Deal found 9/17$447
This American Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/265:15 amFLO - ORD
1 stop4h 50mAmerican Airlines
Mon 12/14:02 pmORD - FLO
2 stops6h 39mAmerican Airlines
Deal found 9/16$460
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/205:37 pmFLO - DTW
1 stop4h 50mAmerican Airlines
Tue 9/236:51 pmDTW - FLO
1 stop4h 25mAmerican Airlines
Deal found 9/17$511
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:14 amFLO - DTW
1 stop4h 09mAmerican Airlines
Sat 9/204:30 pmDTW - FLO
1 stop6h 46mAmerican Airlines
Deal found 9/17$535
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1811:18 amFLO - DTW
2 stops11h 15mAmerican Airlines
Tue 9/2311:30 amDTW - FLO
1 stop5h 42mAmerican Airlines
Deal found 9/17$540
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/185:14 amFLO - DTW
1 stop4h 09mAmerican Airlines
Sun 9/217:21 pmDTW - FLO
1 stop4h 52mAmerican Airlines
Deal found 9/17$559
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/206:14 amFLO - DTW
1 stop6h 48mAmerican Airlines
Sat 9/204:30 pmDTW - FLO
1 stop18h 23mAmerican Airlines
Deal found 9/17$735
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2111:18 amFLO - DTW
1 stop4h 00mAmerican Airlines
Wed 9/246:51 pmDTW - FLO
1 stop4h 25mAmerican Airlines
Deal found 9/15$801

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.

Fly from

Florence

Fly to

Michigan

Route

Depart

Return

Price

FlorenceChicago

FLO - ORD

FLOORD

Florence

Sat 10/11

2:29 pm-7:11 pm

1 stop5h 42m

Chicago O'Hare Intl

Sat 10/18

6:45 am-2:04 pm

2 stops6h 19m

$409

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 10/7

6:14 am-9:30 am

1 stop4h 16m

Chicago O'Hare Intl

Tue 10/14

7:10 am-2:54 pm

1 stop6h 44m

$426

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 10/2

4:57 pm-9:21 pm

1 stop5h 24m

Chicago O'Hare Intl

Mon 10/6

6:36 pm-12:03 am

1 stop4h 27m

$437

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 10/1

5:37 pm-11:12 pm

1 stop6h 35m

Chicago O'Hare Intl

Sun 10/5

8:38 am-4:32 pm

1 stop6h 54m

$437

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 11/25

11:11 am-2:14 pm

1 stop4h 03m

Chicago O'Hare Intl

Mon 12/1

5:00 am-10:45 am

1 stop4h 45m

$444

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 11/26

5:15 am-9:05 am

1 stop4h 50m

Chicago O'Hare Intl

Mon 12/1

4:02 pm-11:41 pm

2 stops6h 39m

$460

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

11:11 am-2:15 pm

1 stop4h 04m

Chicago O'Hare Intl

Sat 3/7

7:00 am-2:03 pm

1 stop6h 03m

$463

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 11/25

6:33 pm-11:56 pm

1 stop6h 23m

Chicago O'Hare Intl

Tue 12/2

5:00 am-9:54 am

1 stop3h 54m

$463

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Best time to book a flight from Florence to Michigan

Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Michigan

What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $250). Flying from Florence, South Carolina to Michigan in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Michigan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Michigan?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Michigan.

  • How long is the flight from Florence, South Carolina to Michigan?

    Airlines like American Airlines fly from Florence, South Carolina to Michigan in about 5h 42m. The time it takes to get you to your destination can typically vary by up to . Florence, South Carolina and Michigan are separated by a distance of 697 mi.

  • Can I find deals for flights from Florence to Michigan that include hotel bookings?

    Yes. In addition to deals on Florence to Michigan flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Michigan?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Michigan.

  • Can I find deals for business class flights from Florence to Michigan?

    Yes. Cheapflights offers flight deals from Florence to Michigan by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

    Currently, August is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $250). Flying from Florence, South Carolina to Michigan in March is currently the most expensive (average of $305). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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