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$378+ Cheap flights from Florence, SC (FLO) to Michigan

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/20. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — DTW
Nov 29 — Dec 61
Sat 11/29
Sat 12/6
1 adult, Economy
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Cheap flight deals from Florence to Michigan

Keep the following information in mind while searching for Florence to Michigan flight deals. Data was last updated October 30, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$378
(American Airlines)
Provider with most accurate pricing for Florence-Detroit (DTT) flight deals.
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Provider most trusted by Cheapflights users for Florence-Detroit (DTT) flights.
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From Florence to Michigan
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Find flight deals from Florence to Michigan

Cheapest flights from Florence to Michigan
Explore the most affordable flight options available from Florence to Michigan. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 30, 2025.

This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2011:11 amFLO - DTW
2 stops11h 20mAmerican Airlines
Sun 11/236:01 amDTW - FLO
2 stops12h 06mAmerican Airlines
Deal found 10/30$378
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:11 amFLO - DTW
1 stop3h 41mAmerican Airlines
Sun 11/1611:59 amDTW - FLO
1 stop6h 08mAmerican Airlines
Deal found 10/30$389
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/45:15 amFLO - ORD
1 stop6h 48mAmerican Airlines
Wed 12/103:44 pmORD - FLO
1 stop6h 09mAmerican Airlines
Deal found 10/30$393
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/146:15 amFLO - ORD
1 stop5h 21mAmerican Airlines
Tue 11/185:00 amORD - FLO
1 stop4h 47mAmerican Airlines
Deal found 10/30$437
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:15 amFLO - ORD
1 stop7h 13mAmerican Airlines
Sat 11/225:34 pmORD - FLO
1 stop5h 07mAmerican Airlines
Deal found 10/30$449
This American Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1311:11 amFLO - ORD
1 stop5h 54mAmerican Airlines
Sun 11/165:00 amORD - FLO
1 stop4h 45mAmerican Airlines
Deal found 10/30$507

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Michigan that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 30, 2025.
Use the filters below to find and compare flights from Florence to Michigan that are best for you.

Fly from

Florence

Fly to

Michigan

Route

Depart

Return

Price

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 11/20

11:11 am-10:31 pm

2 stops11h 20m

Detroit Metropolitan Wayne County

Sun 11/23

6:01 am-6:07 pm

2 stops12h 06m

$378

FlorenceDetroit

FLO - DTW

FLODTW

Florence

Thu 11/13

11:11 am-2:52 pm

1 stop3h 41m

Detroit Metropolitan Wayne County

Sun 11/16

11:59 am-6:07 pm

1 stop6h 08m

$389

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 12/4

5:15 am-11:03 am

1 stop6h 48m

Chicago O'Hare Intl

Wed 12/10

3:44 pm-10:53 pm

1 stop6h 09m

$393

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 11/14

10:29 am-2:57 pm

1 stop5h 28m

Chicago O'Hare Intl

Tue 11/18

2:50 pm-10:53 pm

2 stops7h 03m

$442

FlorenceChicago

FLO - ORD

FLOORD

Florence

Wed 3/4

6:15 am-3:46 pm

2 stops10h 31m

Chicago O'Hare Intl

Sat 3/7

4:05 pm-11:59 pm

1 stop6h 54m

$453

FlorenceChicago

FLO - ORD

FLOORD

Florence

Fri 3/27

11:09 am-3:45 pm

1 stop5h 36m

Chicago O'Hare Intl

Sun 3/29

6:30 pm-11:38 pm

1 stop4h 08m

$497

FlorenceChicago

FLO - ORD

FLOORD

Florence

Thu 11/13

11:11 am-4:05 pm

1 stop5h 54m

Chicago O'Hare Intl

Sun 11/16

5:00 am-10:45 am

1 stop4h 45m

$507

FlorenceChicago

FLO - ORD

FLOORD

Florence

Tue 11/4

11:14 am-2:57 pm

1 stop4h 43m

$439

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/30

Best time to book a flight from Florence to Michigan

Have a flexible travel schedule? Discover the best time to fly to Michigan from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Michigan

What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in December is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from Florence to Michigan. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Michigan?

    Florence (FLO), located 2.3 mi from the city center, is the airport you fly out of when you book flights from Florence to Michigan.

  • How long is the flight from Florence, South Carolina to Michigan?

    Airlines like American Airlines fly from Florence, South Carolina to Michigan in about 11h 20m. The time it takes to get you to your destination can typically vary by up to . Florence, South Carolina and Michigan are separated by a distance of 589 mi.

  • Can I find deals for flights from Florence to Michigan that include hotel bookings?

    Yes. In addition to deals on Florence to Michigan flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Michigan?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Michigan.

  • Can I find deals for business class flights from Florence to Michigan?

    Yes. Cheapflights offers flight deals from Florence to Michigan by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Florence, South Carolina to Michigan?

    Currently, June is the cheapest month in which you can book a flight from Florence, South Carolina to Michigan (average of $71). Flying from Florence, South Carolina to Michigan in December is currently the most expensive (average of $205). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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