$131+ Cheap flights from South Carolina to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MEX
Oct 25 — Nov 11
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from South Carolina to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from South Carolina to Mexico
Cheapest
Best
Last-minute
One-way
Cheapest flights from South Carolina to MexicoExplore the most affordable flight options available from South Carolina to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
Explore the most affordable flight options available from South Carolina to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 25, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:39 am -
1 stop13h 06m
Sat 10/1011:05 am -
1 stop19h 49m
Deal found 9/20![Multiple Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/78:14 pm -
1 stop14h 32m
Wed 11/1111:48 am -
1 stop10h 14m
Deal found 9/24![American Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am -
2 stops9h 10m
Fri 12/113:56 pm -
1 stop8h 03m
Deal found 9/24![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:38 pm -
1 stop17h 07m
Fri 10/237:20 am -
1 stop14h 13m
Deal found 9/20![American Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:30 am -
1 stop7h 04m
Fri 11/68:39 am -
1 stop13h 20m
Deal found 9/23![United Airlines logo]()
$424
This Breeze Airways deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/236:00 am -
Nonstop3h 00m
Sat 12/2610:00 am -
Nonstop2h 31m
Deal found 9/23![Breeze Airways logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/153:00 pm -
2 stops19h 28m
Sat 12/1910:00 am -
Nonstop2h 31m
Deal found 9/21![Multiple Airlines logo]()
$427
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:14 pm -
1 stop14h 32m
Tue 12/81:37 pm -
2 stops9h 14m
Deal found 9/20![American Airlines logo]()
$429
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop7h 32m
Sat 10/1011:05 am -
1 stop19h 33m
Deal found 9/20![Multiple Airlines logo]()
$435
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 am -
2 stops9h 07m
Tue 11/37:00 am -
1 stop15h 26m
Deal found 9/20![American Airlines logo]()
$437
This Aeromexico deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:18 pm -
1 stop4h 50m
Sun 12/66:04 am -
2 stops18h 00m
Deal found 9/20![Aeromexico logo]()
$440
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:00 am -
2 stops31h 41m
Wed 11/115:40 pm -
1 stop17h 23m
Deal found 9/24![Multiple Airlines logo]()
$448
Best flights from South Carolina to MexicoDiscover carefully curated flight deals from South Carolina to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
Discover carefully curated flight deals from South Carolina to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 25, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:00 am -
Nonstop3h 00m
Wed 1/131:56 pm -
1 stop8h 03m
Deal found 9/24![Breeze Airways logo]()
$364
This Aeromexico deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/210:30 am -
1 stop4h 50m
Fri 2/511:00 am -
1 stop10h 46m
Deal found 9/24![Aeromexico logo]()
$424
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/76:30 am -
1 stop9h 07m
Sat 11/148:39 am -
2 stops13h 21m
Deal found 9/23![United Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:20 am -
1 stop10h 07m
Fri 12/111:21 pm -
1 stop10h 34m
Deal found 9/23![American Airlines logo]()
$510
This Southwest deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/810:45 am -
2 stops9h 00m
Tue 12/158:20 am -
2 stops11h 00m
Deal found 9/22![Southwest logo]()
$519
This Delta deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/175:40 am -
1 stop5h 20m
Wed 3/312:15 pm -
1 stop9h 43m
Deal found 9/23![Delta logo]()
$560
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/154:02 pm -
1 stop26h 08m
Wed 10/216:09 pm -
2 stops36h 06m
Deal found 9/24![Multiple Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:30 am -
1 stop10h 02m
Sat 11/1411:15 am -
1 stop8h 44m
Deal found 9/20![United Airlines logo]()
$497
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:59 pm -
1 stop17h 24m
Thu 1/143:27 pm -
1 stop7h 01m
Deal found 9/24![American Airlines logo]()
$510
This Southwest deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:35 am -
2 stops8h 55m
Fri 12/118:20 am -
2 stops13h 55m
Deal found 9/24![Southwest logo]()
$546
This Aeromexico deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/132:07 pm -
1 stop7h 01m
Wed 12/161:45 pm -
1 stop8h 37m
Deal found 9/24![Aeromexico logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:10 am -
2 stops10h 16m
Sat 11/144:41 pm -
1 stop17h 35m
Deal found 9/23![American Airlines logo]()
$511
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/164:00 pm -
2 stops21h 00m
Fri 1/2212:10 pm -
1 stop6h 39m
Deal found 9/24![Delta logo]()
$565
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/910:23 am -
1 stop6h 32m
Mon 11/168:39 am -
1 stop13h 20m
Deal found 9/20![United Airlines logo]()
$535
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/128:20 am -
1 stop6h 35m
Sat 12/1910:55 am -
1 stop8h 10m
Deal found 9/20![Southwest logo]()
$566
This Aeromexico deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/246:00 am -
2 stops11h 38m
Wed 3/34:30 pm -
1 stop7h 05m
Deal found 9/23![Aeromexico logo]()
$570
This Delta deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/246:00 am -
1 stop5h 00m
Wed 3/34:30 pm -
1 stop7h 05m
Deal found 9/22![Delta logo]()
$570
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/177:00 am -
1 stop14h 18m
Sun 1/247:00 am -
1 stop8h 57m
Deal found 9/25![American Airlines logo]()
$522
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:15 am -
1 stop9h 45m
Wed 11/48:20 am -
2 stops10h 05m
Deal found 9/21![Southwest logo]()
$576
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:20 am -
2 stops15h 39m
Wed 11/1112:47 pm -
1 stop8h 12m
Deal found 9/20![United Airlines logo]()
$592
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:00 am -
1 stop9h 10m
Tue 3/166:00 am -
1 stop8h 53m
Deal found 9/24![American Airlines logo]()
$540
This Delta deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/56:00 am -
1 stop9h 20m
Fri 2/125:40 pm -
1 stop5h 55m
Deal found 9/20![Delta logo]()
$595
This Aeromexico deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/117:40 am -
2 stops14h 50m
Sun 2/1410:30 pm -
2 stops22h 16m
Deal found 9/24![Aeromexico logo]()
$637
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:20 am -
1 stop9h 35m
Thu 11/58:20 am -
2 stops13h 45m
Deal found 9/21![Southwest logo]()
$588
This United Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:00 am -
2 stops9h 48m
Sat 10/101:44 pm -
2 stops17h 18m
Deal found 9/20![United Airlines logo]()
$603
This Delta deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1810:08 am -
1 stop5h 17m
Sat 10/246:04 am -
2 stops11h 05m
Deal found 9/24![Delta logo]()
$605
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/135:05 am -
2 stops11h 51m
Sat 11/214:05 pm -
2 stops14h 24m
Deal found 9/24![American Airlines logo]()
$551
This Aeromexico deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/45:30 am -
1 stop6h 50m
Sun 2/711:00 am -
2 stops11h 56m
Deal found 9/20![Aeromexico logo]()
$650
This Southwest deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:05 am -
2 stops12h 40m
Sat 12/1910:45 am -
2 stops12h 15m
Deal found 9/20![Southwest logo]()
$595
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:12 am -
2 stops17h 22m
Wed 2/241:52 pm -
2 stops17h 30m
Deal found 9/20![American Airlines logo]()
$570
Last-minute flights from South Carolina to MexicoDiscover last-minute flight deals from South Carolina to Mexico. Data last updated September 25, 2026 and is based on user searches.
Discover last-minute flight deals from South Carolina to Mexico. Data last updated September 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:39 am -
1 stop13h 06m
Sat 10/1011:05 am -
1 stop19h 49m
Deal found 9/20![Multiple Airlines logo]()
$403
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop7h 32m
Sat 10/1011:05 am -
1 stop19h 33m
Deal found 9/20![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/12:13 pm -
1 stop7h 32m
Tue 10/611:05 am -
1 stop19h 33m
Deal found 9/23![Multiple Airlines logo]()
$488
This Aeromexico deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:25 pm -
1 stop6h 30m
Tue 10/207:01 am -
2 stops15h 58m
Deal found 9/22![Aeromexico logo]()
$479
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/187:38 pm -
1 stop17h 07m
Fri 10/237:20 am -
1 stop14h 13m
Deal found 9/20![American Airlines logo]()
$423
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/227:08 pm -
1 stop22h 14m
Mon 11/21:08 pm -
1 stop7h 18m
Deal found 9/21![American Airlines logo]()
$507
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:25 pm -
1 stop17h 27m
Mon 11/21:08 pm -
2 stops18h 40m
Deal found 9/24![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:12 am -
1 stop5h 13m
Mon 11/211:48 am -
1 stop7h 46m
Deal found 9/22![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:00 am -
2 stops9h 07m
Tue 11/37:00 am -
1 stop15h 26m
Deal found 9/20![American Airlines logo]()
$437
This United Airlines deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:30 am -
1 stop7h 04m
Fri 11/68:39 am -
1 stop13h 20m
Deal found 9/23![United Airlines logo]()
$424
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:00 am -
1 stop10h 25m
Fri 11/63:56 pm -
1 stop8h 03m
Deal found 9/24![American Airlines logo]()
$474
This Aeromexico deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3112:09 pm -
1 stop8h 46m
Fri 11/66:04 am -
2 stops17h 55m
Deal found 9/24![Aeromexico logo]()
$515
One-way flights from South Carolina to MexicoSearch for one-way flight options from South Carolina to Mexico. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
Search for one-way flight options from South Carolina to Mexico. Find affordable one-way fares based on user searches. Data last updated September 25, 2026.
This Breeze Airways deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:00 am -
Nonstop3h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Breeze Airways logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/68:52 pm -
3 stops59h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$158
This Breeze Airways deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/26:00 am -
Nonstop3h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Breeze Airways logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/166:00 am -
Nonstop3h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Breeze Airways logo]()
$177
This American Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:20 am -
2 stops14h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![American Airlines logo]()
$198
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/138:52 pm -
3 stops27h 03m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Multiple Airlines logo]()
$200
This United Airlines deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/287:56 pm -
1 stop14h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![United Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 9/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/279:01 pm -
1 stop19h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/24![Breeze Airways logo]()
$207
This Aeromexico deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/28:10 am -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Aeromexico logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:42 pm -
3 stops23h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/72:58 pm -
3 stops40h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 9/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:27 pm -
3 stops50h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/23![Multiple Airlines logo]()
$226
Find flight deals from South Carolina to Mexico
Keep the following information in mind while searching for South Carolina to Mexico flight deals. Data was last updated September 25, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $296 (Kiwi.com) |
One-way from | $131 (Breeze Airways) |
Popular in | September |
Cheapest in | March |
Average price | $959 |
Good round-trip deal | $678 or less |
Good one-way deal | $131 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from South Carolina to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
Use the filters below to find and compare flights from South Carolina to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Wed 12/30
6:00 am-9:00 am
Nonstop3h 00m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$131
GreenvilleSantiago de Querétaro
GSP Greenville - QRO Santiago de Querétaro
GSPQRO
Greenville
Fri 11/6
8:52 pm-6:53 am
3 stops59h 01m
Santiago de Querétaro
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$158
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Sat 1/2
6:00 am-9:00 am
Nonstop3h 00m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$161
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Sat 1/16
6:00 am-9:00 am
Nonstop3h 00m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$177
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Mon 12/28
7:56 pm-10:29 am
1 stop14h 33m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Wed 2/17
5:30 am-11:00 am
1 stop5h 30m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
CharlestonCancún
CHS Charleston - CUN Cancun
CHSCUN
Charleston
Mon 1/4
7:56 pm-12:10 pm
1 stop16h 14m
Cancun
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$203
GreenvilleMexico City
GSP Greenville - MEX Mexico City Benito Juarez
GSPMEX
Greenville
Fri 11/13
2:49 pm-10:55 pm
2 stops33h 06m
Mexico City Benito Juarez
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$206
GreenvilleSantiago de Querétaro
GSP Greenville - QRO Santiago de Querétaro
GSPQRO
Greenville
Mon 12/7
2:58 pm-6:53 am
3 stops40h 55m
Santiago de Querétaro
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$222
CharlestonSan José del Cabo
CHS Charleston - SJD San José del Cabo Los Cabos
CHSSJD
Charleston
Tue 10/13
6:30 am-5:35 pm
2 stops14h 05m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-2:00 am
Nonstop0h 00m
$227
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from South Carolina to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from South Carolina with our price prediction graph.
CHS-CUN
GSP-QRO
MYR-CUN
CHS-SJD
GSP-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from South Carolina to Mexico
USSC-MX0
CHS-CUN
GSP-QRO
MYR-CUN
CHS-SJD
What is the cheapest month to book a flight from South Carolina to Mexico?
Currently, January is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $599). Flying from South Carolina to Mexico in November is currently the most expensive (average of $734). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How far ahead should I book a flight from South Carolina to Mexico?
The price you pay for your flight from South Carolina to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 49 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from South Carolina to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Return Flight Options
Top destinations
Top regions
Alternative routes for South Carolina to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from South Carolina to Mexico by cabin class
Find flights from South Carolina to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
South Carolina and Mexico flights
Browse other South Carolina and Mexico flight options. Last updated on September 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to South Carolina after your stay in Mexico
South Carolina to Mexico flights
Consider these flights traveling from South Carolina to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 7 airlines flying from South Carolina to Mexico
Discover the top 7 airlines that operate flights from South Carolina to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$194 | Average$613 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$261 | Average$338 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$262 | Average$650 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$315 | Average$510 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$347 | Average$662 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$399 | Average$704 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$451 | Average$586 | FlexibilityNo cancel fee | On-time63% |