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$100+ Cheap flights from South Carolina to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MEX
Dec 20 — Dec 271
Sat 12/20
Sat 12/27
1 adult, Economy
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Find flight deals from South Carolina to Mexico

Cheapest flights from South Carolina to Mexico
Explore the most affordable flight options available from South Carolina to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 20, 2025.

This Expedia deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/79:49 pmCHS - CUN
1 stop15h 24mSpirit Airlines
Thu 12/112:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 11/19$243
This Expedia deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/149:49 pmCHS - CUN
1 stop15h 24mSpirit Airlines
Thu 12/182:36 pmCUN - CHS
1 stop6h 47mSpirit Airlines
Deal found 11/19$277
This Mytrip deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:11 pmCLT - GDL
3 stops30h 24mMultiple Airlines
Tue 12/98:01 amGDL - CLT
Nonstop4h 00mMultiple Airlines
Deal found 11/19$370
This Delta deal was found by Cheapflights users on 11/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/155:25 amCHS - CUN
1 stop10h 08mDelta
Fri 12/191:33 pmCUN - CHS
1 stop8h 31mDelta
Deal found 11/17$379
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:09 amCHS - CUN
2 stops10h 11mAmerican Airlines
Fri 12/195:20 pmCUN - CHS
1 stop7h 25mAmerican Airlines
Deal found 11/18$383
This Mytrip deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/147:00 amSAV - CUN
1 stop6h 13mMultiple Airlines
Sat 12/272:36 pmCUN - SAV
2 stops21h 52mMultiple Airlines
Deal found 11/20$389
This Air Canada deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/69:30 amCLT - CZM
1 stop29h 35mAir Canada
Wed 12/104:00 pmCZM - CLT
1 stop23h 17mAir Canada
Deal found 11/20$389
This Delta deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:25 amCHS - CUN
1 stop10h 09mDelta
Tue 12/28:00 amCUN - CHS
1 stop12h 34mDelta
Deal found 11/18$409
This Kiwi.com deal was found by Cheapflights users on 11/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/23:42 pmCLT - GDL
1 stop25h 46mMultiple Airlines
Wed 12/107:21 amGDL - CLT
1 stop24h 01mMultiple Airlines
Deal found 11/20$412
This American Airlines deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/295:10 amCHS - CUN
2 stops8h 12mAmerican Airlines
Tue 12/25:20 pmCUN - CHS
1 stop15h 25mAmerican Airlines
Deal found 11/18$413
This Mytrip deal was found by Cheapflights users on 11/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/22:46 pmMYR - CUN
2 stops19h 58mSpirit Airlines
Wed 12/32:44 pmCUN - MYR
2 stops17h 16mSpirit Airlines
Deal found 11/18$423
This Kiwi.com deal was found by Cheapflights users on 11/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/12:46 pmMYR - CUN
1 stop22h 49mMultiple Airlines
Sat 12/62:36 pmCUN - MYR
2 stops19h 29mMultiple Airlines
Deal found 11/19$426

Cheap flight deals from South Carolina to Mexico

Keep the following information in mind while searching for South Carolina to Mexico flight deals. Data was last updated November 20, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$243
(Expedia)

One-way from

$100
(Kiwi.com)

Good round-trip deal

$280 or less
Provider with most accurate pricing for Myrtle Beach Intl-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Myrtle Beach Intl-Mexico City Benito Juarez flights.
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From South Carolina to Mexico
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One-way flight from South Carolina to Mexico
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Price to beat on a round-trip flight from South Carolina to Mexico.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
Use the filters below to find and compare flights from South Carolina to Mexico that are best for you.

Fly from

South Carolina

Fly to

Mexico

Route

Depart

Return

Price

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Sun 12/7

9:49 pm-1:13 pm

1 stop15h 24m

Cancun

Thu 12/11

2:36 pm-11:00 am

2 stops20h 24m

$300

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Sun 1/25

8:15 pm-9:13 am

2 stops12h 58m

Cancun

Thu 1/29

1:21 pm-7:20 pm

1 stop5h 59m

$341

CharlotteGuadalajara

CLT - GDL

CLTGDL

Charlotte Douglas

Thu 1/15

6:25 am-12:48 pm

1 stop7h 23m

Guadalajara Miguel Hidal

Tue 1/20

2:13 pm-11:54 pm

1 stop8h 41m

$348

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Thu 1/8

8:15 pm-12:16 pm

1 stop16h 01m

Cancun

Mon 1/12

1:21 pm-7:20 pm

1 stop5h 59m

$349

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Tue 1/27

3:01 pm-12:16 pm

2 stops21h 15m

Cancun

Sun 2/1

1:21 pm-5:36 pm

1 stop28h 15m

$353

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Fri 1/2

10:18 pm-1:31 pm

1 stop15h 13m

Cancun

Wed 1/7

3:38 pm-5:36 pm

3 stops25h 58m

$374

CharlotteGuadalajara

CLT - GDL

CLTGDL

Charlotte Douglas

Tue 12/2

3:42 pm-4:28 pm

1 stop25h 46m

Guadalajara Miguel Hidal

Tue 12/9

8:01 am-1:01 pm

Nonstop4h 00m

$379

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Wed 12/10

12:51 pm-9:20 pm

1 stop8h 29m

Cancun

Wed 12/17

8:00 am-3:15 pm

1 stop7h 15m

$379

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Mon 12/15

5:25 am-3:33 pm

1 stop10h 08m

Cancun

Fri 12/19

1:33 pm-10:04 pm

1 stop8h 31m

$379

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Mon 12/15

6:30 am-3:33 pm

1 stop9h 03m

Cancun

Mon 12/22

1:40 pm-11:58 pm

1 stop10h 18m

$379

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/18

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Mexico

What is the cheapest month to book a flight from South Carolina to Mexico?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $183). Flying from South Carolina to Mexico in March is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MX?

Find hourly flight availability from South Carolina to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 20, 2025.

One of the essential ways to save on airfare from South Carolina to Mexico is to remain as flexible as possible. Flights that are in the morning tend to be the most expensive. A flight in the evening could potentially save you up to 8% on airfare.

What is the cheapest day to fly from South Carolina to Mexico?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Mexico. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Mexico flight should consider departing on Wednesday at noon when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Mexico?

    For as low as $348, Spirit Airlines can have you in Mexico from South Carolina in 7h 23m. Airlines will cover a distance of 1694 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Mexico one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $114. Users have also found prices from $119 and $128 on Breeze Airways and Volaris, respectively.

  • Can I find deals for flights from South Carolina to Mexico that include hotel bookings?

    Yes. In addition to deals on South Carolina to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Mexico.

  • Can I find deals for business class flights from South Carolina to Mexico?

    Yes. Cheapflights offers flight deals from South Carolina to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Mexico?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $183). Flying from South Carolina to Mexico in March is currently the most expensive (average of $348). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for South Carolina to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Mexico

Discover the top 6 airlines that operate flights from South Carolina to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 20, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$250Average$351FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$275Average$711FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$303Average$609FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$325Average$627FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$361Average$659FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$465Average$707FlexibilityNo cancel feeOn-time63%

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