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$122+ Cheap flights from South Carolina to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MEX
Dec 2 — Dec 91
Tue 12/2
Tue 12/9
1 adult, Economy
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Find flight deals from South Carolina to Mexico

Cheapest flights from South Carolina to Mexico
Explore the most affordable flight options available from South Carolina to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 2, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/16:50 amCHS - CUN
1 stop6h 45mSpirit Airlines
Fri 12/52:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 10/31$271
This Flightnetwork deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Flightnetwork is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/119:49 pmCHS - CUN
1 stop15h 24mSpirit Airlines
Sun 12/142:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 10/31$276
This Cheapflightsfares deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/59:49 pmCHS - CUN
1 stop15h 24mSpirit Airlines
Mon 12/82:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 10/31$328
This Priceline deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/296:50 amCHS - CUN
1 stop6h 45mMultiple Airlines
Sat 2/286:55 pmCUN - CHS
Nonstop2h 35mMultiple Airlines
Deal found 11/1$342
This Cheapflightsfares deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/49:49 pmCHS - CUN
1 stop15h 24mSpirit Airlines
Mon 12/82:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 10/31$347
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/169:02 amCHS - CUN
2 stops28h 33mSpirit Airlines
Thu 12/42:36 pmCUN - CHS
1 stop6h 18mSpirit Airlines
Deal found 10/30$350
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/169:02 amCHS - CUN
2 stops28h 33mMultiple Airlines
Sat 11/2210:12 amCUN - CHS
1 stop22h 25mMultiple Airlines
Deal found 10/30$359
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/147:00 amCHS - CUN
1 stop6h 35mSpirit Airlines
Mon 11/172:50 pmCUN - CHS
3 stops26h 16mSpirit Airlines
Deal found 11/1$361
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:46 pmMYR - CUN
1 stop22h 49mSpirit Airlines
Thu 11/202:44 pmCUN - MYR
1 stop9h 10mSpirit Airlines
Deal found 10/31$381
This Cheapflightsfares deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/226:50 amCHS - CUN
1 stop10h 23mSpirit Airlines
Thu 11/272:44 pmCUN - CHS
1 stop7h 21mSpirit Airlines
Deal found 11/1$384
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/133:59 pmMYR - CUN
2 stops21h 36mMultiple Airlines
Thu 11/202:44 pmCUN - MYR
1 stop9h 10mMultiple Airlines
Deal found 10/31$394
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/2010:47 amCLT - GDL
2 stops31h 54mMultiple Airlines
Tue 11/258:01 amGDL - CLT
Nonstop4h 00mMultiple Airlines
Deal found 10/31$406

Cheap flight deals from South Carolina to Mexico

Keep the following information in mind while searching for South Carolina to Mexico flight deals. Data was last updated November 2, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$261
(Breeze Airways)

One-way from

$122
(Kiwi.com)

Popular in

December

Cheapest in

April

Average price

$737

Good round-trip deal

$280 or less
Provider with most accurate pricing for Myrtle Beach Intl-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Myrtle Beach Intl-Mexico City Benito Juarez flights.
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From South Carolina to Mexico
Search Deals
One-way flight from South Carolina to Mexico
Search Deals
Highest demand for flights based on searches. 16% potential increase in price ($132 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($39 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals
Price to beat on a round-trip flight from South Carolina to Mexico.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
Use the filters below to find and compare flights from South Carolina to Mexico that are best for you.

Fly from

South Carolina

Fly to

Mexico

Route

Depart

Return

Price

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Mon 12/1

6:50 am-1:35 pm

1 stop6h 45m

Cancun

Fri 12/5

2:36 pm-8:54 pm

1 stop6h 18m

$271

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Sat 1/17

3:05 pm-5:55 pm

Nonstop2h 50m

Cancun

Sat 1/24

6:55 pm-9:30 pm

Nonstop2h 35m

$291

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Sat 1/17

3:05 pm-5:55 pm

Nonstop2h 50m

Cancun

Sat 1/24

1:35 pm-10:45 am

1 stop21h 10m

$314

CharlotteGuadalajara

CLT - GDL

CLTGDL

Charlotte Douglas

Sat 3/28

2:41 pm-5:19 pm

Nonstop4h 38m

Guadalajara Miguel Hidal

Sat 4/4

8:13 am-2:31 pm

Nonstop4h 18m

$341

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Sun 11/16

9:02 am-1:35 pm

2 stops28h 33m

Cancun

Fri 12/5

2:36 pm-8:54 pm

1 stop6h 18m

$350

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Fri 1/23

5:40 pm-10:42 am

2 stops17h 02m

Cancun

Sun 1/25

10:15 am-8:34 am

3 stops22h 19m

$364

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Thu 11/13

2:46 pm-1:35 pm

1 stop22h 49m

Cancun

Thu 11/20

2:44 pm-11:54 pm

1 stop9h 10m

$381

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Mon 12/15

9:22 am-5:15 pm

1 stop7h 53m

Cancun

Fri 12/19

11:18 am-6:07 pm

1 stop6h 49m

$387

CharlotteGuadalajara

CLT - GDL

CLTGDL

Charlotte Douglas

Thu 11/20

10:47 am-5:41 pm

2 stops31h 54m

Guadalajara Miguel Hidal

Tue 11/25

8:01 am-1:01 pm

Nonstop4h 00m

$406

CharlotteCancún

CLT - CUN

CLTCUN

Charlotte Douglas

Thu 1/1

9:38 pm-1:31 pm

1 stop15h 53m

Cancun

Thu 1/8

10:15 am-8:37 am

3 stops22h 22m

$411

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/1

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Mexico

What is the cheapest month to book a flight from South Carolina to Mexico?

Currently, October is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $185). Flying from South Carolina to Mexico in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MX?

Find hourly flight availability from South Carolina to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 2, 2025.

One of the essential ways to save on airfare from South Carolina to Mexico is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 5% on airfare.

What is the cheapest day to fly from South Carolina to Mexico?

Use this chart to determine the cheapest time to fly round-trip from South Carolina to Mexico. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their South Carolina to Mexico flight should consider departing on Wednesday at noon when fares are most often at their lowest. Friday evenings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Mexico?

    For as low as $291, Spirit Airlines can have you in Mexico from South Carolina in 2h 50m. Airlines will cover a distance of 920 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Mexico one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $137. Users have also found prices from $199 and $221 on American Airlines and Frontier, respectively.

  • Can I find deals for flights from South Carolina to Mexico that include hotel bookings?

    Yes. In addition to deals on South Carolina to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Mexico.

  • Can I find deals for business class flights from South Carolina to Mexico?

    Yes. Cheapflights offers flight deals from South Carolina to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Mexico?

    Currently, October is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $185). Flying from South Carolina to Mexico in March is currently the most expensive (average of $352). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from South Carolina to Mexico

Discover the top 6 airlines that operate flights from South Carolina to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 2, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$250Average$351FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$275Average$718FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$303Average$618FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$325Average$631FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$361Average$659FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$465Average$707FlexibilityNo cancel feeOn-time63%

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