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$120+ Cheap flights from South Carolina to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
CHS — MEX
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from South Carolina to Mexico

Keep the following information in mind while searching for South Carolina to Mexico flight deals. Data was last updated September 17, 2025.

Round-trip from

$307
(Kiwi.com)

One-way from

$120
(Kiwi.com)

Popular in

December

Cheapest in

May
From South Carolina to Mexico
Search Deals
One-way flight from South Carolina to Mexico
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($72 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($32 potential savings vs. average RT price).
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Find flight deals from South Carolina to Mexico

Cheapest flights from South Carolina to Mexico
Explore the most affordable flight options available from South Carolina to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1910:11 amCHS - CUN
1 stop27h 33mSpirit Airlines
Sat 10/251:49 pmCUN - CHS
1 stop18h 17mSpirit Airlines
Deal found 9/16$307
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/610:11 amCHS - CUN
1 stop27h 33mSpirit Airlines
Thu 10/91:49 pmCUN - CHS
1 stop18h 17mSpirit Airlines
Deal found 9/16$315
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/135:40 pmCHS - CUN
1 stop18h 47mSpirit Airlines
Tue 11/181:35 pmCUN - CHS
1 stop21h 10mSpirit Airlines
Deal found 9/16$320
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/3010:11 amCHS - CUN
1 stop27h 33mSpirit Airlines
Thu 11/61:35 pmCUN - CHS
1 stop21h 10mSpirit Airlines
Deal found 9/15$324
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/63:33 pmCHS - CUN
1 stop17h 31mMultiple Airlines
Sat 10/119:09 amCUN - CHS
1 stop22h 28mMultiple Airlines
Deal found 9/16$330
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/142:59 pmCHS - CUN
1 stop18h 05mMultiple Airlines
Sat 10/181:49 pmCUN - CHS
1 stop18h 17mMultiple Airlines
Deal found 9/16$334
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/279:56 amCHS - CUN
1 stop27h 48mMultiple Airlines
Mon 11/310:09 amCUN - CHS
1 stop22h 28mMultiple Airlines
Deal found 9/16$338
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/132:59 pmCHS - CUN
1 stop18h 11mMultiple Airlines
Sun 11/161:35 pmCUN - CHS
1 stop21h 10mMultiple Airlines
Deal found 9/15$339
This Cheapflightsfares deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/276:43 pmMYR - CUN
1 stop14h 21mSpirit Airlines
Sun 11/22:50 pmCUN - MYR
1 stop5h 14mSpirit Airlines
Deal found 9/16$341
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/232:59 pmCHS - CUN
1 stop18h 05mMultiple Airlines
Wed 10/291:49 pmCUN - CHS
1 stop18h 17mMultiple Airlines
Deal found 9/17$341
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/42:59 pmCHS - CUN
1 stop18h 11mMultiple Airlines
Mon 11/1010:15 amCUN - CHS
1 stop22h 22mMultiple Airlines
Deal found 9/17$344
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/267:58 pmMYR - CUN
1 stop13h 06mSpirit Airlines
Sun 11/210:09 amCUN - MYR
1 stop8h 49mSpirit Airlines
Deal found 9/15$348

Cheapflights Fare Finder

 
Customize your flight search to find flights from South Carolina to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from South Carolina to Mexico that are best for you.

Fly from

South Carolina

Fly to

Mexico

Route

Depart

Return

Price

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Mon 10/6

10:11 am-12:44 pm

1 stop27h 33m

Cancun

Thu 10/9

1:49 pm-9:06 am

1 stop18h 17m

$315

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Tue 10/14

2:59 pm-8:04 am

1 stop18h 05m

Cancun

Sat 10/18

1:49 pm-9:06 am

1 stop18h 17m

$334

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Mon 10/27

6:43 pm-8:04 am

1 stop14h 21m

Cancun

Sun 11/2

2:50 pm-8:04 pm

1 stop5h 14m

$341

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Thu 10/23

2:59 pm-8:04 am

1 stop18h 05m

Cancun

Wed 10/29

1:49 pm-9:06 am

1 stop18h 17m

$341

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Sun 10/26

7:58 pm-8:04 am

1 stop13h 06m

Cancun

Sun 11/2

10:09 am-6:58 pm

1 stop8h 49m

$348

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Fri 10/31

6:43 pm-8:04 am

1 stop14h 21m

Cancun

Fri 11/7

10:15 am-7:35 pm

1 stop9h 20m

$350

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Thu 10/30

10:11 am-11:16 am

2 stops26h 05m

Cancun

Sun 11/2

11:22 am-9:01 am

2 stops21h 39m

$350

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Thu 11/13

5:20 pm-1:16 pm

1 stop19h 56m

Cancun

Thu 11/20

11:10 am-4:48 pm

1 stop5h 38m

$368

Myrtle BeachCancún

MYR - CUN

MYRCUN

Myrtle Beach Intl

Thu 11/13

11:46 am-9:41 am

2 stops21h 55m

Cancun

Tue 11/18

10:15 am-7:35 pm

1 stop9h 20m

$386

CharlestonCancún

CHS - CUN

CHSCUN

Charleston

Wed 11/5

6:05 am-1:44 pm

1 stop7h 39m

Cancun

Tue 11/11

1:35 pm-10:27 pm

1 stop8h 52m

$387

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/17

Showing 1-10 of 60 results
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Best time to book a flight from South Carolina to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from South Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from South Carolina to Mexico

What is the cheapest month to book a flight from South Carolina to Mexico?

Currently, May is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $387). Flying from South Carolina to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SC to MX?

Find hourly flight availability from South Carolina to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from South Carolina to Mexico as you normally would.

Related info for your journey

Find useful and relevant information for your journey from South Carolina to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from South Carolina to Mexico?

    For as low as $411, Spirit Airlines can have you in Mexico from South Carolina in 3h 01m. Airlines will cover a distance of 1043 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from South Carolina to Mexico one-way?

    For one-way options, check prices for Spirit Airlines. According to our data, you can fly for as low as $135. Users have also found prices from $177 and $198 on Air Canada and Southwest, respectively.

  • Can I find deals for flights from South Carolina to Mexico that include hotel bookings?

    Yes. In addition to deals on South Carolina to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from South Carolina to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from South Carolina to Mexico.

  • Can I find deals for business class flights from South Carolina to Mexico?

    Yes. Cheapflights offers flight deals from South Carolina to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from South Carolina to Mexico?

    Currently, May is the cheapest month in which you can book a flight from South Carolina to Mexico (average of $387). Flying from South Carolina to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for South Carolina to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from South Carolina to Mexico

Discover the top 7 airlines that operate flights from South Carolina to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
JetBlueCheapest$220Average$458FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$250Average$351FlexibilityNo cancel feeOn-time65%
United AirlinesCheapest$275Average$693FlexibilityNo cancel feeOn-time69%
AeromexicoCheapest$303Average$562FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$324Average$624FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$361Average$661FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$465Average$714FlexibilityNo cancel feeOn-time63%

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