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$230+ Cheap flights from Panama City, FL (ECP) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/5. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
Aug 19 — Aug 261
Tue 8/19
Tue 8/26
1 adult, Economy
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Cheap flight deals from Panama City to Mexico

Keep the following information in mind while searching for Panama City to Mexico flight deals. Data was last updated August 14, 2025.

Round-trip from

$408
(Delta)

One-way from

$230
(Delta)

Popular in

October

Cheapest in

March

Average price

$561
From Panama City NW Florida Beaches to Mexico
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One-way flight from Panama City NW Florida Beaches to Mexico
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Highest demand for flights based on searches. 20% potential increase in price ($166 potential increase over avg. RT price).
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Cheapest flight prices on average. 4% potential price decrease ($29 potential savings vs. average RT price).
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Average for round-trip flights in August 2025
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Find flight deals from Panama City to Mexico

Cheapest flights from Panama City to Mexico
Explore the most affordable flight options available from Panama City to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2025.

This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:23 amECP - CUN
1 stop10h 39mDelta
Thu 11/2012:25 pmCUN - ECP
2 stops11h 18mDelta
Deal found 8/13$408
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/136:00 amECP - CUN
1 stop8h 20mDelta
Thu 11/207:50 amCUN - ECP
2 stops12h 48mDelta
Deal found 8/14$433
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:30 amECP - CUN
1 stop12h 50mUnited Airlines
Sat 10/47:51 amCUN - ECP
1 stop8h 25mUnited Airlines
Deal found 8/13$458
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:04 amECP - CUN
1 stop9h 16mDelta
Thu 11/612:05 pmCUN - ECP
1 stop12h 05mDelta
Deal found 8/13$459
This Aeromexico deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/111:04 amECP - CUN
1 stop9h 16mAeromexico
Thu 11/68:00 amCUN - ECP
1 stop8h 25mAeromexico
Deal found 8/12$472
This Southwest deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/127:15 amECP - CUN
2 stops11h 30mSouthwest
Thu 11/208:20 amCUN - ECP
2 stops11h 45mSouthwest
Deal found 8/13$484
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/67:10 amECP - CUN
1 stop13h 10mDelta
Fri 9/128:00 amCUN - ECP
1 stop9h 56mDelta
Deal found 8/14$486
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/137:10 amECP - CUN
2 stops12h 35mAmerican Airlines
Thu 11/2011:50 amCUN - ECP
2 stops12h 59mAmerican Airlines
Deal found 8/14$503
This Southwest deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/278:05 amECP - CUN
1 stop5h 35mSouthwest
Sat 10/411:55 amCUN - ECP
2 stops7h 45mSouthwest
Deal found 8/14$505
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/276:00 amECP - CUN
1 stop8h 20mDelta
Sat 10/411:12 amCUN - ECP
2 stops11h 51mDelta
Deal found 8/13$511
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/66:06 pmECP - CUN
2 stops16h 51mAmerican Airlines
Fri 9/124:26 pmCUN - ECP
2 stops18h 50mAmerican Airlines
Deal found 8/12$516
This Aeromexico deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/27:00 amECP - MEX
2 stops8h 25mAeromexico
Mon 10/67:25 amMEX - ECP
2 stops9h 07mAeromexico
Deal found 8/14$547

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
Use the filters below to find and compare flights from Panama City to Mexico that are best for you.

Fly from

Panama City

Fly to

Mexico

Route

Depart

Return

Price

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 11/12

11:15 am-9:02 pm

1 stop8h 47m

Cancun

Thu 11/20

8:10 am-5:53 pm

1 stop10h 43m

$408

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Thu 11/13

6:00 am-3:20 pm

1 stop8h 20m

Cancun

Thu 11/20

2:56 pm-7:38 pm

1 stop5h 42m

$433

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Sat 9/27

6:30 am-7:20 pm

1 stop12h 50m

Cancun

Sat 10/4

7:51 am-4:16 pm

1 stop8h 25m

$458

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Sat 11/1

11:04 am-8:20 pm

1 stop9h 16m

Cancun

Thu 11/6

12:05 pm-11:10 pm

1 stop12h 05m

$459

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Sat 11/1

11:04 am-8:20 pm

1 stop9h 16m

Cancun

Thu 11/6

8:00 am-3:25 pm

1 stop8h 25m

$472

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 11/12

7:15 am-7:45 pm

2 stops11h 30m

Cancun

Thu 11/20

8:20 am-7:05 pm

2 stops11h 45m

$484

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Sat 9/6

1:53 pm-8:20 pm

1 stop6h 27m

Cancun

Fri 9/12

12:15 pm-11:03 pm

2 stops10h 48m

$486

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Thu 10/2

7:00 am-2:25 pm

2 stops8h 25m

Mexico City Benito Juarez

Mon 10/6

7:25 am-5:32 pm

2 stops9h 07m

$547

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 9/9

6:32 am-12:10 pm

1 stop6h 38m

Mexico City Benito Juarez

Tue 9/23

5:00 am-3:18 pm

1 stop9h 18m

$552

Panama CityPuerto Vallarta

ECP - PVR

ECPPVR

Panama City NW Florida Beaches

Sat 9/27

6:06 pm-12:27 pm

2 stops19h 21m

Puerto Vallarta Ordaz

Tue 10/28

11:15 am-10:53 pm

2 stops10h 38m

$560

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/13

Showing 1-10 of 21 results
1
2
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Best time to book a flight from Panama City to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico

What is the cheapest month to book a flight from Panama City, Florida to Mexico?

Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $387). Flying from Panama City, Florida to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MX?

Find hourly flight availability from Panama City to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 14, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Panama City, Florida to Mexico as you normally would.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated August 14, 2025.
Get a feel of what it's like to fly with Delta, Aeromexico, and United Airlines from Panama City to Mexico by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,980 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Aeromexico
7.5
Good
1,723 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,916 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,980 reviews

Comfort

7.9

Entertainment

7.9

Crew

8.5

Food

7.3

Boarding

8.2

Overall

8.0

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mexico?

    Panama City NW Florida Beaches (ECP) is the airport you will fly out of if you book a flight from Panama City to Mexico. It is only a 16.0 mi journey to NW Florida Beaches (ECP) from Panama City’s city center.

  • What are the cheapest airlines to fly from Panama City, Florida to Mexico one-way?

    For one-way options, check prices for Delta. According to our data, you can fly for as low as $230. Users have also found prices from $269 and $292 on American Airlines and United Airlines, respectively.

  • What are the most popular routes from Panama City, Florida to Mexico?

    The most popular route from Panama City, Florida to Mexico is Panama City NW Florida Beaches - Cancun. You may also consider Panama City NW Florida Beaches - Mexico City Benito Juarez or Panama City NW Florida Beaches - Puerto Vallarta Ordaz.

  • Can I find deals for flights from Panama City to Mexico that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico.

  • Can I find deals for business class flights from Panama City to Mexico?

    Yes. Cheapflights offers flight deals from Panama City to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $387). Flying from Panama City, Florida to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Panama City to Mexico

Discover the top 4 airlines that operate flights from Panama City to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$284Average$511FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$362Average$586FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$421Average$584FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$441Average$569FlexibilityNo cancel feeOn-time69%

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