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$306+ Cheap flights from Panama City, FL (ECP) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/30. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
Jan 31 — Feb 71
Sat 1/31
Sat 2/7
1 adult, Economy
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Cheap flight deals from Panama City to Mexico

Best flights from Panama City to Mexico
Discover carefully curated flight deals from Panama City to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated January 1, 2026.

This Aeromexico deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:00 amECP - CUN
1 stop5h 34mAeromexico
Tue 3/1712:44 pmCUN - ECP
1 stop7h 03mAeromexico
Deal found 12/30$456
This Delta deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/118:25 amECP - CUN
2 stops11h 37mDelta
Wed 3/1811:22 amCUN - ECP
2 stops11h 42mDelta
Deal found 12/31$461
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2012:38 pmECP - MEX
1 stop6h 57mAmerican Airlines
Fri 2/278:00 amMEX - ECP
1 stop7h 08mAmerican Airlines
Deal found 12/29$550
This United Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/241:01 pmECP - MEX
1 stop11h 09mUnited Airlines
Tue 4/144:40 amMEX - ECP
1 stop10h 32mUnited Airlines
Deal found 12/31$550
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:05 amECP - CUN
1 stop7h 20mDelta
Tue 3/2410:00 amCUN - ECP
1 stop7h 58mDelta
Deal found 12/30$461
This Aeromexico deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/117:05 amECP - CUN
1 stop13h 15mAeromexico
Wed 3/184:45 pmCUN - ECP
1 stop6h 19mAeromexico
Deal found 12/31$461
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/296:44 amECP - MEX
1 stop15h 01mAmerican Airlines
Fri 5/811:20 amMEX - ECP
1 stop9h 38mAmerican Airlines
Deal found 12/31$550
This United Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:30 amECP - PVR
1 stop8h 39mUnited Airlines
Sun 3/292:52 pmPVR - ECP
1 stop6h 07mUnited Airlines
Deal found 12/29$593
This American Airlines deal was found by Cheapflights users on 12/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/2410:20 amECP - MEX
2 stops9h 15mAmerican Airlines
Tue 4/1411:20 amMEX - ECP
2 stops10h 32mAmerican Airlines
Deal found 12/31$555
This Delta deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/37:15 amECP - MEX
1 stop12h 06mDelta
Wed 5/138:40 amMEX - ECP
1 stop9h 16mDelta
Deal found 12/30$567
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/313:27 pmECP - PVR
2 stops22h 16mAmerican Airlines
Sat 2/285:20 pmPVR - ECP
2 stops19h 23mAmerican Airlines
Deal found 12/30$603
This American Airlines deal was found by Cheapflights users on 12/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:42 amECP - PVR
1 stop7h 03mAmerican Airlines
Sun 3/291:45 pmPVR - ECP
2 stops19h 21mAmerican Airlines
Deal found 12/29$608
This American Airlines deal was found by Cheapflights users on 12/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/234:40 pmECP - PVR
2 stops18h 42mAmerican Airlines
Mon 4/2712:29 pmPVR - ECP
2 stops21h 29mAmerican Airlines
Deal found 12/30$633

Find flight deals from Panama City to Mexico

Keep the following information in mind while searching for Panama City to Mexico flight deals. Data was last updated January 1, 2026.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$430
(Aeromexico)

One-way from

$306
(American Airlines)

Popular in

October

Cheapest in

September

Average price

$675
Provider with most accurate pricing for Panama City NW Florida Beaches-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Mexico City Benito Juarez flights.
Search Deals
From Panama City NW Florida Beaches to Mexico
Search Deals
One-way flight from Panama City NW Florida Beaches to Mexico
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($72 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($35 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
Use the filters below to find and compare flights from Panama City to Mexico that are best for you.

Fly from

Panama City

Fly to

Mexico

Route

Depart

Return

Price

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Mon 3/9

6:00 am-11:34 am

1 stop5h 34m

Cancun

Tue 3/17

12:44 pm-7:47 pm

1 stop7h 03m

$456

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 3/11

8:25 am-8:02 pm

2 stops11h 37m

Cancun

Wed 3/18

11:22 am-11:04 pm

2 stops11h 42m

$461

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Tue 3/17

7:05 am-2:25 pm

1 stop7h 20m

Cancun

Tue 3/24

10:00 am-5:58 pm

1 stop7h 58m

$461

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 3/11

7:05 am-8:20 pm

1 stop13h 15m

Cancun

Wed 3/18

4:45 pm-11:04 pm

1 stop6h 19m

$461

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Fri 2/20

12:38 pm-7:35 pm

1 stop6h 57m

Mexico City Benito Juarez

Fri 2/27

8:00 am-3:08 pm

1 stop7h 08m

$550

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 2/24

1:01 pm-12:10 am

1 stop11h 09m

Mexico City Benito Juarez

Tue 4/14

4:40 am-4:12 pm

1 stop10h 32m

$550

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Wed 4/29

6:44 am-8:45 pm

1 stop15h 01m

Mexico City Benito Juarez

Fri 5/8

11:20 am-9:58 pm

1 stop9h 38m

$550

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 2/24

10:20 am-7:35 pm

2 stops9h 15m

Mexico City Benito Juarez

Tue 4/14

11:20 am-10:52 pm

2 stops10h 32m

$555

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Sun 5/3

7:15 am-6:21 pm

1 stop12h 06m

Mexico City Benito Juarez

Wed 5/13

8:40 am-6:56 pm

1 stop9h 16m

$567

Panama CityPuerto Vallarta

ECP - PVR

ECPPVR

Panama City NW Florida Beaches

Wed 3/25

6:30 am-2:09 pm

1 stop8h 39m

Puerto Vallarta Ordaz

Sun 3/29

2:52 pm-9:59 pm

1 stop6h 07m

$593

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/31

Showing 1-10 of 17 results
1
2

Best time to book a flight from Panama City to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico

What is the cheapest month to book a flight from Panama City, Florida to Mexico?

Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $331). Flying from Panama City, Florida to Mexico in April is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated January 1, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and Aeromexico from Panama City to Mexico by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,017 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,017 reviews
Delta
7.9
Good
8,017 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,131 reviews
Delta
7.9
Good
8,017 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Aeromexico
7.4
Good
1,619 reviews
Delta
7.9
Good
8,017 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,071 reviews
Delta
7.9
Good
8,017 reviews

Entertainment

7.8

Crew

8.5

Food

7.2

Boarding

8.1

Comfort

7.9

Overall

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mexico?

    Panama City NW Florida Beaches (ECP) is the airport you will fly out of if you book a flight from Panama City to Mexico. It is only a 16.0 mi journey to NW Florida Beaches (ECP) from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Mexico?

    Departing from Panama City, Florida to Mexico will take you 5h 34m. The distance from Panama City, Florida to Mexico is about 647 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Mexico?

    The most popular route from Panama City, Florida to Mexico is Panama City NW Florida Beaches - Cancun. You may also consider Panama City NW Florida Beaches - Mexico City Benito Juarez or Panama City NW Florida Beaches - Puerto Vallarta Ordaz.

  • Can I find deals for flights from Panama City to Mexico that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico.

  • Can I find deals for business class flights from Panama City to Mexico?

    Yes. Cheapflights offers flight deals from Panama City to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico?

    Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $331). Flying from Panama City, Florida to Mexico in April is currently the most expensive (average of $462). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Panama City to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Mexico

Discover the top 4 airlines that operate flights from Panama City to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 1, 2026.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$254Average$473FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$362Average$551FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$428Average$596FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$489Average$624FlexibilityNo cancel feeOn-time71%

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