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$300+ Cheap flights from Panama City, FL (ECP) to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/8. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Cheap flight deals from Panama City to Mexico

Keep the following information in mind while searching for Panama City to Mexico flight deals. Data was last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$430
(Aeromexico)

One-way from

$300
(United Airlines)

Popular in

October

Cheapest in

September

Average price

$807
Provider with most accurate pricing for Panama City NW Florida Beaches-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Panama City NW Florida Beaches-Mexico City Benito Juarez flights.
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From Panama City NW Florida Beaches to Mexico
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One-way flight from Panama City NW Florida Beaches to Mexico
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Highest demand for flights based on searches. 16% potential increase in price ($129 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($33 potential savings vs. average RT price).
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Average for round-trip flights in November 2025
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Find flight deals from Panama City to Mexico

Cheapest flights from Panama City to Mexico
Explore the most affordable flight options available from Panama City to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:30 amECP - PVR
1 stop6h 25mAmerican Airlines
Thu 12/2512:08 pmPVR - ECP
1 stop6h 47mAmerican Airlines
Deal found 11/12$556
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:30 amECP - CUN
1 stop12h 48mUnited Airlines
Sun 12/76:30 amCUN - ECP
1 stop8h 28mUnited Airlines
Deal found 11/11$589
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/72:43 pmECP - PVR
2 stops20h 45mAmerican Airlines
Tue 12/164:23 pmPVR - ECP
2 stops19h 15mAmerican Airlines
Deal found 11/12$606
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/129:23 amECP - CUN
2 stops10h 37mDelta
Thu 11/208:36 amCUN - ECP
2 stops12h 56mDelta
Deal found 11/11$641
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/139:23 amECP - CUN
1 stop5h 11mDelta
Thu 11/206:00 amCUN - ECP
2 stops10h 58mDelta
Deal found 11/12$642
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/246:30 amECP - MEX
1 stop5h 45mUnited Airlines
Thu 12/185:45 amMEX - ECP
1 stop16h 09mUnited Airlines
Deal found 11/12$649
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/125:50 pmECP - CUN
1 stop15h 41mAmerican Airlines
Thu 11/201:05 pmCUN - ECP
1 stop9h 10mAmerican Airlines
Deal found 11/12$652
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/113:00 pmECP - MEX
1 stop9h 10mUnited Airlines
Sun 12/145:45 amMEX - ECP
1 stop8h 13mUnited Airlines
Deal found 11/11$675
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:15 amECP - CUN
2 stops12h 30mAmerican Airlines
Sun 12/712:03 pmCUN - ECP
1 stop10h 13mAmerican Airlines
Deal found 11/11$686
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/116:30 amECP - MEX
2 stops17h 40mAmerican Airlines
Sat 12/1312:25 amMEX - ECP
2 stops12h 28mAmerican Airlines
Deal found 11/11$701
This United Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:00 pmECP - MEX
1 stop7h 10mUnited Airlines
Wed 11/267:50 amMEX - ECP
1 stop6h 07mUnited Airlines
Deal found 11/12$714
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/245:55 pmECP - MEX
2 stops16h 00mAmerican Airlines
Wed 11/2611:20 amMEX - ECP
1 stop9h 55mAmerican Airlines
Deal found 11/12$718

Cheapflights Fare Finder

 
Customize your flight search to find flights from Panama City to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Panama City to Mexico that are best for you.

Fly from

Panama City

Fly to

Mexico

Route

Depart

Return

Price

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Mon 3/9

9:23 am-7:59 pm

1 stop10h 36m

Cancun

Tue 3/17

10:10 am-6:58 pm

1 stop8h 48m

$430

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Thu 1/8

6:00 am-2:03 pm

1 stop7h 03m

Cancun

Wed 1/14

4:40 pm-10:55 pm

1 stop7h 15m

$430

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Tue 3/17

7:45 am-3:30 pm

1 stop7h 45m

Cancun

Tue 3/24

8:00 am-6:58 pm

1 stop10h 58m

$435

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 3/11

7:45 am-7:59 pm

1 stop12h 14m

Cancun

Wed 3/18

2:00 pm-10:42 pm

1 stop8h 42m

$435

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 3/11

7:45 am-7:59 pm

1 stop12h 14m

Cancun

Wed 3/18

2:00 pm-10:42 pm

1 stop8h 42m

$435

Panama CityCancún

ECP - CUN

ECPCUN

Panama City NW Florida Beaches

Wed 1/21

9:24 am-11:30 pm

2 stops13h 06m

Cancun

Wed 1/28

1:40 pm-6:14 pm

1 stop5h 34m

$435

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Fri 1/30

7:02 am-11:20 pm

1 stop16h 18m

Mexico City Benito Juarez

Mon 2/2

8:00 am-9:19 pm

1 stop13h 19m

$518

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 1/13

6:00 am-3:15 pm

1 stop9h 15m

Mexico City Benito Juarez

Tue 1/20

12:35 pm-6:14 pm

1 stop5h 39m

$544

Panama CityMexico City

ECP - MEX

ECPMEX

Panama City NW Florida Beaches

Tue 1/13

12:03 pm-9:55 pm

1 stop9h 52m

Mexico City Benito Juarez

Mon 1/19

12:25 am-1:04 pm

2 stops12h 39m

$555

Panama CityPuerto Vallarta

ECP - PVR

ECPPVR

Panama City NW Florida Beaches

Mon 12/15

6:30 am-3:27 pm

1 stop8h 57m

Puerto Vallarta Ordaz

Thu 12/25

12:08 pm-6:55 pm

1 stop6h 47m

$556

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 21 results
1
2
3

Best time to book a flight from Panama City to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Panama City with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Panama City to Mexico

What is the cheapest month to book a flight from Panama City, Florida to Mexico?

Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $276). Flying from Panama City, Florida to Mexico in October is currently the most expensive (average of $445). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from ECP to MX?

Find hourly flight availability from Panama City to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from Panama City, Florida to Mexico in the evening. If you’re flexible enough to do this you can expect to save up to 36% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Mexico

Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated November 13, 2025.
Get a feel of what it's like to fly with Delta, United Airlines, and Aeromexico from Panama City to Mexico by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
9,015 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Aeromexico
7.4
Good
1,672 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Comfort

7.9

Entertainment

7.9

Boarding

8.1

Overall

7.9

Food

7.3

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Panama City to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Panama City to Mexico?

    Panama City NW Florida Beaches (ECP) is the airport you will fly out of if you book a flight from Panama City to Mexico. It is only a 16.0 mi journey to NW Florida Beaches (ECP) from Panama City’s city center.

  • How long is the flight from Panama City, Florida to Mexico?

    Departing from Panama City, Florida to Mexico will take you 7h 45m. The distance from Panama City, Florida to Mexico is about 647 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the most popular routes from Panama City, Florida to Mexico?

    The most popular route from Panama City, Florida to Mexico is Panama City NW Florida Beaches - Cancun. You may also consider Panama City NW Florida Beaches - Puerto Vallarta Ordaz or Panama City NW Florida Beaches - Mexico City Benito Juarez.

  • Can I find deals for flights from Panama City to Mexico that include hotel bookings?

    Yes. In addition to deals on Panama City to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Panama City to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Panama City to Mexico.

  • Can I find deals for business class flights from Panama City to Mexico?

    Yes. Cheapflights offers flight deals from Panama City to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Panama City, Florida to Mexico?

    Currently, November is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $276). Flying from Panama City, Florida to Mexico in October is currently the most expensive (average of $445). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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See prices for flight routes from nearby airports that may be better suited for you.
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Top 4 airlines flying from Panama City to Mexico

Discover the top 4 airlines that operate flights from Panama City to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$254Average$468FlexibilityNo cancel feeOn-timeN/A
DeltaCheapest$362Average$606FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$421Average$591FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$441Average$614FlexibilityNo cancel feeOn-time69%

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