$249+ Cheap flights from Panama City, FL (ECP) to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/17. Fares are subject to change and may not be available on all flights or dates of travel.
ECP — MEX
Mar 24 — Mar 311
1 adult, Economy
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Find cheap flights from Panama City to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Panama City to MexicoExplore the most affordable flight options available from Panama City to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
Explore the most affordable flight options available from Panama City to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 22, 2026.
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2111:15 am
ECP
- CUN
1 stop9h 08m
Delta
Tue 8/48:00 am
CUN
- ECP
1 stop5h 52m
Delta
Deal found 2/21![Delta logo]()
$490
This Aeromexico deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:05 am
ECP
- CUN
1 stop5h 35m
Aeromexico
Fri 4/241:50 pm
CUN
- ECP
1 stop9h 22m
Aeromexico
Deal found 2/21![Aeromexico logo]()
$510
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:30 am
ECP
- CUN
1 stop12h 49m
United Airlines
Mon 4/137:51 am
CUN
- ECP
1 stop14h 08m
United Airlines
Deal found 2/18![United Airlines logo]()
$513
This Aeromexico deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/266:00 am
ECP
- CUN
1 stop14h 10m
Aeromexico
Thu 12/31:40 pm
CUN
- ECP
1 stop6h 56m
Aeromexico
Deal found 2/18![Aeromexico logo]()
$515
This Delta deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/205:49 am
ECP
- CUN
2 stops10h 51m
Delta
Fri 4/2412:25 pm
CUN
- ECP
2 stops10h 47m
Delta
Deal found 2/18![Delta logo]()
$516
This United Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/76:30 am
ECP
- CUN
1 stop12h 49m
United Airlines
Tue 4/142:49 pm
CUN
- ECP
1 stop7h 10m
United Airlines
Deal found 2/21![United Airlines logo]()
$518
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/74:40 pm
ECP
- CUN
2 stops18h 53m
American Airlines
Tue 4/1412:33 pm
CUN
- ECP
2 stops10h 19m
American Airlines
Deal found 2/21![American Airlines logo]()
$522
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:10 am
ECP
- CUN
1 stop9h 09m
United Airlines
Sat 4/182:49 pm
CUN
- ECP
1 stop7h 10m
United Airlines
Deal found 2/20![United Airlines logo]()
$529
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:30 am
ECP
- CUN
1 stop7h 48m
United Airlines
Sun 4/197:51 am
CUN
- ECP
1 stop14h 08m
United Airlines
Deal found 2/19![United Airlines logo]()
$537
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/137:05 am
ECP
- CUN
1 stop6h 56m
Aeromexico
Sat 4/186:50 am
CUN
- ECP
2 stops16h 22m
Aeromexico
Deal found 2/20![Aeromexico logo]()
$541
This Aeromexico deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:45 am
ECP
- MEX
1 stop14h 30m
Aeromexico
Thu 9/37:05 am
MEX
- ECP
1 stop9h 46m
Aeromexico
Deal found 2/21![Aeromexico logo]()
$578
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/2811:15 am
ECP
- MEX
1 stop10h 59m
Delta
Mon 8/39:40 am
MEX
- ECP
2 stops12h 06m
Delta
Deal found 2/19![Delta logo]()
$583
Best flights from Panama City to MexicoDiscover carefully curated flight deals from Panama City to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
Discover carefully curated flight deals from Panama City to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 22, 2026.
This Aeromexico deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:05 am
ECP
- CUN
1 stop6h 56m
Aeromexico
Fri 4/241:50 pm
CUN
- ECP
1 stop5h 46m
Aeromexico
Deal found 2/18![Aeromexico logo]()
$510
This United Airlines deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:30 am
ECP
- CUN
1 stop12h 49m
United Airlines
Mon 4/137:51 am
CUN
- ECP
1 stop14h 08m
United Airlines
Deal found 2/18![United Airlines logo]()
$513
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/207:05 am
ECP
- CUN
1 stop6h 56m
Delta
Fri 4/2412:25 pm
CUN
- ECP
2 stops10h 47m
Delta
Deal found 2/21![Delta logo]()
$516
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/217:05 am
ECP
- CUN
1 stop7h 24m
American Airlines
Tue 6/212:29 pm
CUN
- ECP
2 stops11h 11m
American Airlines
Deal found 2/21![American Airlines logo]()
$557
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1310:10 am
ECP
- CUN
1 stop9h 09m
United Airlines
Sat 4/182:49 pm
CUN
- ECP
1 stop7h 10m
United Airlines
Deal found 2/20![United Airlines logo]()
$529
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
ECP
- CUN
1 stop9h 45m
Delta
Tue 3/242:10 pm
CUN
- ECP
1 stop5h 37m
Delta
Deal found 2/21![Delta logo]()
$543
This Aeromexico deal was found by Cheapflights users on 2/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:30 pm
ECP
- MEX
1 stop8h 44m
Aeromexico
Mon 8/37:05 am
MEX
- ECP
1 stop11h 31m
Aeromexico
Deal found 2/18![Aeromexico logo]()
$578
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/2912:33 pm
ECP
- MEX
1 stop6h 59m
American Airlines
Fri 5/85:15 pm
MEX
- ECP
2 stops15h 48m
American Airlines
Deal found 2/19![American Airlines logo]()
$589
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:30 am
ECP
- CUN
1 stop7h 48m
United Airlines
Sun 4/197:51 am
CUN
- ECP
1 stop14h 08m
United Airlines
Deal found 2/19![United Airlines logo]()
$537
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/287:45 am
ECP
- MEX
2 stops8h 45m
Delta
Mon 8/38:40 am
MEX
- ECP
2 stops13h 06m
Delta
Deal found 2/19![Delta logo]()
$583
This Aeromexico deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:00 am
ECP
- MEX
1 stop8h 55m
Aeromexico
Wed 8/128:40 am
MEX
- ECP
1 stop8h 57m
Aeromexico
Deal found 2/21![Aeromexico logo]()
$601
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/289:00 am
ECP
- MEX
1 stop5h 15m
United Airlines
Mon 8/39:35 am
MEX
- ECP
1 stop11h 22m
United Airlines
Deal found 2/19![United Airlines logo]()
$584
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/166:56 pm
ECP
- PVR
1 stop16h 42m
American Airlines
Sun 6/214:05 pm
PVR
- ECP
1 stop21h 27m
American Airlines
Deal found 2/19![American Airlines logo]()
$655
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/39:21 am
ECP
- MEX
1 stop13h 29m
Aeromexico
Tue 5/123:15 pm
MEX
- ECP
1 stop6h 36m
Aeromexico
Deal found 2/20![Aeromexico logo]()
$604
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:49 am
ECP
- MEX
1 stop9h 06m
Delta
Wed 5/137:05 am
MEX
- ECP
1 stop10h 31m
Delta
Deal found 2/21![Delta logo]()
$604
This Delta deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/35:49 am
ECP
- MEX
1 stop9h 06m
Delta
Tue 5/129:05 am
MEX
- ECP
1 stop6h 49m
Delta
Deal found 2/21![Delta logo]()
$604
This American Airlines deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/231:08 pm
ECP
- PVR
2 stops22h 14m
American Airlines
Mon 4/273:10 pm
PVR
- ECP
2 stops18h 48m
American Airlines
Deal found 2/22![American Airlines logo]()
$667
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:30 am
ECP
- PVR
1 stop5h 40m
United Airlines
Sun 4/262:52 pm
PVR
- ECP
2 stops21h 31m
United Airlines
Deal found 2/20![United Airlines logo]()
$737
Last-minute flights from Panama City to MexicoDiscover last-minute flight deals from Panama City to Mexico. Data last updated February 22, 2026 and is based on user searches.
Discover last-minute flight deals from Panama City to Mexico. Data last updated February 22, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/266:30 am
ECP
- MEX
1 stop10h 15m
United Airlines
Wed 3/45:45 am
MEX
- ECP
1 stop6h 19m
United Airlines
Deal found 2/19![United Airlines logo]()
$794
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/264:34 pm
ECP
- MEX
2 stops17h 21m
American Airlines
Tue 3/312:25 am
MEX
- ECP
2 stops12h 23m
American Airlines
Deal found 2/19![American Airlines logo]()
$799
This Delta deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2712:10 pm
ECP
- CUN
1 stop8h 01m
Delta
Tue 3/311:18 am
CUN
- ECP
2 stops12h 21m
Delta
Deal found 2/20![Delta logo]()
$666
This American Airlines deal was found by Cheapflights users on 2/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:42 am
ECP
- CUN
1 stop7h 38m
American Airlines
Tue 3/32:25 pm
CUN
- ECP
1 stop8h 52m
American Airlines
Deal found 2/21![American Airlines logo]()
$668
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:30 am
ECP
- MEX
1 stop5h 45m
United Airlines
Sun 3/112:25 pm
MEX
- ECP
1 stop9h 31m
United Airlines
Deal found 2/19![United Airlines logo]()
$834
This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/288:03 am
ECP
- MEX
1 stop7h 12m
Aeromexico
Sun 3/110:30 pm
MEX
- ECP
2 stops24h 09m
Aeromexico
Deal found 2/19![Aeromexico logo]()
$1,084
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2810:31 am
ECP
- MEX
2 stops12h 51m
American Airlines
Sun 3/18:00 am
MEX
- ECP
2 stops15h 49m
American Airlines
Deal found 2/19![American Airlines logo]()
$2,446
This Aeromexico deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/26:00 am
ECP
- CUN
1 stop9h 45m
Aeromexico
Wed 3/41:40 pm
CUN
- ECP
1 stop6h 12m
Aeromexico
Deal found 2/19![Aeromexico logo]()
$633
This United Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/101:00 pm
ECP
- MEX
1 stop5h 55m
United Airlines
Sat 3/146:50 am
MEX
- ECP
1 stop14h 07m
United Airlines
Deal found 2/19![United Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/108:20 am
ECP
- MEX
2 stops12h 55m
American Airlines
Sat 3/145:00 am
MEX
- ECP
2 stops17h 49m
American Airlines
Deal found 2/19![American Airlines logo]()
$789
This Air Canada deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/102:10 pm
ECP
- MEX
2 stops22h 20m
Multiple Airlines
Sat 3/1412:30 pm
MEX
- ECP
3 stops23h 40m
Multiple Airlines
Deal found 2/19![Multiple Airlines logo]()
$3,168
One-way flights from Panama City to MexicoSearch for one-way flight options from Panama City to Mexico. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
Search for one-way flight options from Panama City to Mexico. Find affordable one-way fares based on user searches. Data last updated February 22, 2026.
This United Airlines deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:30 am
ECP
- CUN
1 stop12h 48m
United Airlines
Deal found 2/20![United Airlines logo]()
$249
This Southwest deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/77:10 am
ECP
- CUN
1 stop6h 50m
Southwest
Deal found 2/20![Southwest logo]()
$260
This Aeromexico deal was found by Cheapflights users on 2/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/177:05 am
ECP
- CUN
2 stops18h 12m
Aeromexico
Deal found 2/20![Aeromexico logo]()
$301
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:43 pm
ECP
- MEX
2 stops16h 12m
Delta
Deal found 2/22![Delta logo]()
$334
This Delta deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/56:00 am
ECP
- CUN
1 stop9h 45m
Delta
Deal found 2/19![Delta logo]()
$353
This Aeromexico deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/208:25 am
ECP
- MEX
2 stops14h 05m
Aeromexico
Deal found 2/22![Aeromexico logo]()
$354
This Delta deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/198:25 am
ECP
- MEX
2 stops11h 40m
Delta
Deal found 2/22![Delta logo]()
$369
This American Airlines deal was found by Cheapflights users on 2/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/57:19 am
ECP
- CUN
2 stops8h 01m
American Airlines
Deal found 2/19![American Airlines logo]()
$388
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/206:00 am
ECP
- MEX
3 stops19h 01m
WestJet
Deal found 2/22![WestJet logo]()
$909
This Kiwi.com deal was found by Cheapflights users on 2/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/224:23 pm
ECP
- MEX
3 stops33h 07m
Multiple Airlines
Deal found 2/22![Multiple Airlines logo]()
$1,021
Find flight deals from Panama City to Mexico
Keep the following information in mind while searching for Panama City to Mexico flight deals. Data was last updated February 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $490 (Delta) |
One-way from | $249 (United Airlines) |
Popular in | October |
Cheapest in | September |
Average price | $572 |
Cheapflights Fare Finder
Customize your flight search to find flights from Panama City to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
Use the filters below to find and compare flights from Panama City to Mexico that are best for you.
Fly from
Panama City
Fly to
Mexico
Route
Depart
Return
Price
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Mon 4/20
7:05 am-2:01 pm
1 stop6h 56m
Cancun
Fri 4/24
1:50 pm-7:36 pm
1 stop5h 46m
$510
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Wed 4/8
6:30 am-7:19 pm
1 stop12h 49m
Cancun
Mon 4/13
7:51 am-9:59 pm
1 stop14h 08m
$513
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Mon 4/20
7:05 am-2:01 pm
1 stop6h 56m
Cancun
Fri 4/24
12:25 pm-11:12 pm
2 stops10h 47m
$516
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Mon 4/13
10:10 am-7:19 pm
1 stop9h 09m
Cancun
Sat 4/18
2:49 pm-9:59 pm
1 stop7h 10m
$529
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Tue 4/14
6:30 am-2:18 pm
1 stop7h 48m
Cancun
Sun 4/19
7:51 am-9:59 pm
1 stop14h 08m
$537
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Tue 3/17
6:00 am-3:45 pm
1 stop9h 45m
Cancun
Tue 3/24
2:10 pm-7:47 pm
1 stop5h 37m
$543
Panama CityCancún
ECP - CUN
ECPCUN
Panama City NW Florida Beaches
Thu 5/21
7:05 am-2:29 pm
1 stop7h 24m
Cancun
Tue 6/2
12:29 pm-11:40 pm
2 stops11h 11m
$557
Panama CityMexico City
ECP - MEX
ECPMEX
Panama City NW Florida Beaches
Thu 7/30
1:30 pm-9:14 pm
1 stop8h 44m
Mexico City Benito Juarez
Mon 8/3
7:05 am-7:36 pm
1 stop11h 31m
$578
Panama CityMexico City
ECP - MEX
ECPMEX
Panama City NW Florida Beaches
Tue 7/28
7:45 am-3:30 pm
2 stops8h 45m
Mexico City Benito Juarez
Mon 8/3
8:40 am-10:46 pm
2 stops13h 06m
$583
Panama CityMexico City
ECP - MEX
ECPMEX
Panama City NW Florida Beaches
Tue 7/28
9:00 am-1:15 pm
1 stop5h 15m
Mexico City Benito Juarez
Mon 8/3
9:35 am-9:57 pm
1 stop11h 22m
$584
Showing 1-10 of 27 results
Best time to book a flight from Panama City to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Panama City with our price prediction graph.
ECP-CUN
ECP-MEX
ECP-PVR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Panama City to Mexico
ECP-MX0
ECP-CUN
ECP-MEX
ECP-PVR
What is the cheapest month to book a flight from Panama City, Florida to Mexico?
Currently, March is the cheapest month in which you can book a flight from Panama City, Florida to Mexico (average of $327). Flying from Panama City, Florida to Mexico in February is currently the most expensive (average of $471). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Mexico
Get insights into the airlines that provide service to Mexico. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mexico. Reviews last updated February 22, 2026.
Get a feel of what it's like to fly with Delta, United Airlines, and Aeromexico from Panama City to Mexico by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Comfort
7.9
Boarding
8.1
Entertainment
7.8
Overall
7.9
Crew
8.5
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Panama City to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Panama City to Mexico
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Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
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Panama City and Mexico flights
Browse other Panama City and Mexico flight options. Last updated on February 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Panama City to Mexico flights
Consider these flights traveling from Panama City to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 4 airlines flying from Panama City to Mexico
Discover the top 4 airlines that operate flights from Panama City to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$226 | Average$473 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$362 | Average$557 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$428 | Average$592 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$489 | Average$632 | FlexibilityNo cancel fee | On-time71% |