$140+ Cheap flights from Missouri to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/19. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Oct 22 — Oct 291
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Mexico
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 pm -
1 stop16h 42m
Wed 10/2112:42 pm -
1 stop9h 00m
Deal found 9/17![American Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:32 pm -
1 stop21h 58m
Thu 10/88:40 am -
1 stop10h 08m
Deal found 9/21![Multiple Airlines logo]()
$383
This Trip.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:40 pm -
1 stop19h 10m
Mon 10/262:10 pm -
1 stop25h 13m
Deal found 9/18![Air Canada logo]()
$385
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:59 am -
2 stops13h 33m
Tue 12/158:15 am -
1 stop7h 35m
Deal found 9/17![Delta logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:43 pm -
2 stops21h 06m
Wed 10/211:54 pm -
1 stop21h 58m
Deal found 9/18![Multiple Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
1 stop5h 39m
Fri 12/1111:21 am -
2 stops13h 44m
Deal found 9/17![Delta logo]()
$388
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/65:38 pm -
2 stops18h 02m
Tue 12/156:04 am -
2 stops14h 15m
Deal found 9/17![Delta logo]()
$391
This CheapOair deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:00 am -
Nonstop3h 28m
Sat 12/128:00 am -
1 stop8h 26m
Deal found 9/17![Multiple Airlines logo]()
$394
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/74:05 pm -
1 stop17h 35m
Mon 12/149:30 pm -
1 stop18h 56m
Deal found 9/22![Air Canada logo]()
$396
This Justfly.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/118:43 pm -
1 stop20h 17m
Thu 11/198:00 am -
1 stop11h 47m
Deal found 9/20![Frontier logo]()
$400
This Trip.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
Nonstop3h 09m
Wed 10/219:05 pm -
1 stop23h 15m
Deal found 9/21![Multiple Airlines logo]()
$402
This Aeromexico deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/81:20 pm -
1 stop6h 48m
Wed 12/96:04 am -
2 stops11h 30m
Deal found 9/17![Aeromexico logo]()
$403
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/187:20 am -
1 stop12h 55m
Fri 1/221:28 pm -
2 stops11h 11m
Deal found 9/17![Delta logo]()
$388
This FlightHub deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/238:29 pm -
1 stop20h 59m
Tue 12/19:02 am -
1 stop10h 31m
Deal found 9/18![Frontier logo]()
$430
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/159:00 am -
1 stop6h 42m
Sun 11/223:48 pm -
1 stop7h 04m
Deal found 9/17![United Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/235:25 am -
1 stop10h 02m
Fri 11/61:44 pm -
1 stop9h 40m
Deal found 9/17![American Airlines logo]()
$480
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:05 am -
2 stops9h 15m
Fri 10/3011:05 am -
2 stops8h 40m
Deal found 9/17![Southwest logo]()
$499
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/151:37 pm -
1 stop9h 08m
Thu 10/228:40 am -
1 stop10h 08m
Deal found 9/17![Multiple Airlines logo]()
$501
This Volaris deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/156:00 am -
1 stop13h 55m
Fri 2/196:45 am -
1 stop9h 42m
Deal found 9/18![Volaris logo]()
$570
This Aeromexico deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/187:05 am -
2 stops12h 05m
Mon 11/237:40 am -
2 stops16h 16m
Deal found 9/19![Aeromexico logo]()
$595
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/179:59 am -
2 stops14h 31m
Thu 3/256:05 am -
2 stops10h 10m
Deal found 9/18![Delta logo]()
$451
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
1 stop8h 03m
Sun 11/223:48 pm -
1 stop7h 04m
Deal found 9/17![United Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:12 pm -
1 stop16h 17m
Sat 10/2412:38 pm -
1 stop10h 50m
Deal found 9/17![American Airlines logo]()
$501
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/59:59 am -
2 stops13h 29m
Sat 1/93:05 pm -
1 stop7h 53m
Deal found 9/17![Delta logo]()
$456
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:43 pm -
2 stops20h 22m
Fri 10/237:58 am -
1 stop10h 50m
Deal found 9/17![Multiple Airlines logo]()
$504
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/89:05 am -
2 stops9h 40m
Tue 12/152:10 pm -
2 stops9h 15m
Deal found 9/21![Southwest logo]()
$529
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:15 am -
1 stop5h 39m
Sat 11/78:39 am -
1 stop6h 34m
Deal found 9/17![United Airlines logo]()
$504
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:00 am -
1 stop8h 06m
Wed 11/189:24 am -
2 stops13h 46m
Deal found 9/17![Delta logo]()
$472
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/112:47 pm -
1 stop30h 23m
Tue 12/157:00 am -
2 stops28h 17m
Deal found 9/22![Multiple Airlines logo]()
$525
This Volaris deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:16 pm -
1 stop10h 29m
Sun 10/257:00 am -
1 stop8h 58m
Deal found 9/17![Volaris logo]()
$588
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/98:35 am -
2 stops10h 10m
Wed 11/188:20 am -
2 stops8h 15m
Deal found 9/21![Southwest logo]()
$550
This United Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:15 am -
1 stop5h 39m
Tue 12/158:39 am -
2 stops9h 56m
Deal found 9/21![United Airlines logo]()
$509
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/59:59 am -
2 stops13h 29m
Wed 12/96:04 am -
2 stops11h 30m
Deal found 9/17![Delta logo]()
$472
This American Airlines deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:00 am -
2 stops9h 56m
Mon 11/164:35 pm -
1 stop15h 55m
Deal found 9/21![American Airlines logo]()
$589
This Aeromexico deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/56:00 am -
2 stops12h 05m
Mon 11/98:35 am -
2 stops15h 21m
Deal found 9/22![Aeromexico logo]()
$657
This Mytrip deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
3 stops26h 25m
Wed 10/144:10 pm -
3 stops30h 03m
Deal found 9/21![Multiple Airlines logo]()
$558
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/246:25 am -
1 stop6h 15m
Sat 10/3111:35 am -
Nonstop3h 25m
Deal found 9/17![Southwest logo]()
$559
This United Airlines deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:28 am -
1 stop6h 27m
Tue 11/103:31 pm -
2 stops18h 51m
Deal found 9/19![United Airlines logo]()
$513
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/249:59 am -
2 stops13h 31m
Sat 3/610:35 am -
2 stops12h 23m
Deal found 9/21![Delta logo]()
$493
This Mytrip deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:43 pm -
2 stops26h 32m
Sun 10/256:10 pm -
2 stops24h 38m
Deal found 9/17![Multiple Airlines logo]()
$577
This Aeromexico deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:08 am -
2 stops14h 12m
Sat 12/197:05 am -
1 stop10h 38m
Deal found 9/17![Aeromexico logo]()
$699
This Frontier deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1912:53 pm -
1 stop10h 05m
Fri 10/237:58 am -
1 stop10h 50m
Deal found 9/18![Frontier logo]()
$808
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated September 22, 2026 and is based on user searches.
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:55 am -
1 stop11h 15m
Sun 11/18:00 am -
1 stop8h 23m
Deal found 9/22![Air Canada logo]()
$411
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:32 pm -
1 stop21h 58m
Thu 10/88:40 am -
1 stop10h 08m
Deal found 9/21![Multiple Airlines logo]()
$383
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:55 am -
1 stop11h 15m
Tue 10/2010:00 am -
1 stop8h 41m
Deal found 9/22![Air Canada logo]()
$406
This Trip.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/128:55 am -
1 stop24h 55m
Fri 10/1610:50 am -
1 stop27h 10m
Deal found 9/19![Air Canada logo]()
$404
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/126:35 pm -
2 stops29h 10m
Mon 10/197:00 am -
1 stop8h 58m
Deal found 9/21![Multiple Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 pm -
1 stop16h 42m
Wed 10/2112:42 pm -
1 stop9h 00m
Deal found 9/17![American Airlines logo]()
$365
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/178:43 pm -
2 stops21h 06m
Wed 10/211:54 pm -
1 stop21h 58m
Deal found 9/18![Multiple Airlines logo]()
$387
This Trip.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:40 pm -
1 stop19h 10m
Mon 10/262:10 pm -
1 stop25h 13m
Deal found 9/18![Air Canada logo]()
$385
This Trip.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
Nonstop3h 09m
Wed 10/219:05 pm -
1 stop23h 15m
Deal found 9/21![Multiple Airlines logo]()
$402
This Trip.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/192:40 pm -
1 stop19h 10m
Fri 10/239:05 pm -
1 stop16h 55m
Deal found 9/19![Air Canada logo]()
$409
This Cheapflightsfares deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
Nonstop3h 09m
Fri 10/239:55 am -
1 stop7h 03m
Deal found 9/19![Frontier logo]()
$414
This Air Canada deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:05 pm -
1 stop17h 35m
Tue 11/38:00 am -
1 stop8h 26m
Deal found 9/22![Air Canada logo]()
$396
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:24 pm -
2 stops40h 34m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:44 pm -
3 stops43h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$142
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:44 pm -
2 stops28h 01m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$146
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 pm -
1 stop16h 42m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:35 pm -
2 stops28h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$167
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:00 am -
1 stop7h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Delta logo]()
$167
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:14 pm -
1 stop10h 31m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:02 pm -
2 stops10h 43m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$174
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/197:24 pm -
2 stops45h 46m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
2 stops28h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:35 pm -
3 stops44h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:35 pm -
3 stops44h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$178
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $365 (American Airlines) |
One-way from | $140 (Kiwi.com) |
Popular in | October |
Cheapest in | April |
Average price | $755 |
Good round-trip deal | $543 or less |
Good one-way deal | $331 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Wed 10/21
6:35 pm-10:15 pm
2 stops28h 40m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$167
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Mon 11/16
7:00 am-1:25 pm
1 stop7h 25m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$167
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Tue 10/20
9:59 am-10:30 pm
2 stops14h 31m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$167
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Sun 11/15
12:14 pm-10:45 pm
1 stop10h 31m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$169
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Mon 12/14
6:00 am-4:45 pm
1 stop10h 45m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$183
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Wed 10/14
6:35 pm-10:15 pm
2 stops28h 40m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$186
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sun 11/15
7:00 am-1:25 pm
1 stop7h 25m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$191
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Fri 10/23
6:35 pm-6:00 pm
3 stops49h 25m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$191
Kansas CityMexico City
MCI Kansas City - MEX Mexico City Benito Juarez
MCIMEX
Kansas City
Fri 11/6
8:43 pm-10:45 pm
2 stops50h 02m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$193
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Tue 10/20
6:15 am-12:48 pm
1 stop8h 33m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-PVR
STL-MEX
STL-SJD
MCI-SJD
MCI-MEX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-PVR
STL-MEX
STL-SJD
MCI-SJD
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, January is the cheapest month in which you can book a flight from Missouri to Mexico (average of $560). Flying from Missouri to Mexico in December is currently the most expensive (average of $719). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from Missouri to Mexico?
The price you pay for your flight from Missouri to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 53 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on September 22, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 10 airlines flying from Missouri to Mexico
Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$179 | Average$597 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$187 | Average$441 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$193 | Average$553 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$195 | Average$550 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$207 | Average$446 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$365 | Average$649 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$388 | Average$687 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$404 | Average$560 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$424 | Average$655 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |