$157+ Cheap flights from Missouri to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/5. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Nov 24 — Dec 11
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:20 pm -
1 stop22h 00m
Thu 12/101:58 pm -
1 stop8h 38m
Deal found 10/22![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:30 pm -
1 stop16h 22m
Thu 12/31:02 pm -
1 stop8h 01m
Deal found 10/21![American Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:30 am -
Nonstop3h 09m
Wed 10/2811:23 am -
Nonstop3h 15m
Deal found 10/21![Volaris logo]()
$364
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:20 am -
2 stops10h 36m
Wed 12/161:02 pm -
1 stop9h 35m
Deal found 10/21![American Airlines logo]()
$367
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:20 am -
Nonstop3h 14m
Tue 11/242:05 pm -
Nonstop3h 20m
Deal found 10/20![Frontier logo]()
$368
This Cheapflightsfares deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:00 am -
Nonstop3h 28m
Fri 12/112:15 pm -
Nonstop3h 25m
Deal found 10/20![Frontier logo]()
$369
This Priceline deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
Nonstop3h 14m
Tue 11/242:05 pm -
Nonstop3h 20m
Deal found 10/20![Frontier logo]()
$371
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/126:44 pm -
1 stop16h 48m
Fri 12/184:23 pm -
1 stop16h 06m
Deal found 10/21![American Airlines logo]()
$375
This Southwest deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
1 stop7h 40m
Tue 12/152:05 pm -
1 stop8h 05m
Deal found 10/24![Southwest logo]()
$375
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:44 pm -
1 stop16h 40m
Sat 11/214:22 pm -
1 stop8h 02m
Deal found 10/21![American Airlines logo]()
$375
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/38:24 pm -
1 stop19h 03m
Mon 12/73:50 pm -
1 stop8h 02m
Deal found 10/20![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:13 am -
1 stop6h 37m
Wed 2/243:59 pm -
1 stop19h 11m
Deal found 10/20![American Airlines logo]()
$382
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 25, 2026.
This Delta deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/16:00 am -
1 stop7h 29m
Thu 2/410:35 am -
2 stops11h 51m
Deal found 10/24![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/36:15 am -
1 stop6h 42m
Tue 2/92:03 pm -
1 stop7h 43m
Deal found 10/23![United Airlines logo]()
$385
This Southwest deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:25 am -
1 stop7h 50m
Fri 1/155:10 pm -
1 stop7h 45m
Deal found 10/23![Southwest logo]()
$474
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:29 pm -
3 stops26h 26m
Fri 12/116:10 pm -
2 stops25h 25m
Deal found 10/20![Multiple Airlines logo]()
$541
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/106:50 am -
2 stops13h 28m
Fri 1/151:57 pm -
2 stops9h 40m
Deal found 10/20![American Airlines logo]()
$543
This Volaris deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:14 pm -
1 stop10h 31m
Mon 11/911:10 am -
1 stop12h 06m
Deal found 10/21![Volaris logo]()
$560
This FlightHub deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/77:59 pm -
2 stops26h 46m
Mon 11/95:50 am -
2 stops13h 24m
Deal found 10/20![Frontier logo]()
$723
This Alaska Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/33:54 pm -
2 stops20h 25m
Sun 2/71:10 pm -
2 stops24h 46m
Deal found 10/23![Alaska Airlines logo]()
$742
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/216:00 am -
2 stops13h 48m
Wed 4/282:01 pm -
1 stop8h 35m
Deal found 10/23![Delta logo]()
$375
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:02 am -
2 stops10h 30m
Sat 2/62:11 pm -
1 stop7h 19m
Deal found 10/24![United Airlines logo]()
$413
This Aeromexico deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/161:20 pm -
2 stops11h 05m
Wed 11/186:32 am -
2 stops15h 38m
Deal found 10/20![Aeromexico logo]()
$868
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:13 am -
1 stop6h 46m
Sun 11/223:50 pm -
2 stops16h 30m
Deal found 10/22![Delta logo]()
$425
This Southwest deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/155:30 am -
2 stops7h 55m
Sat 11/215:10 pm -
1 stop8h 30m
Deal found 10/21![Southwest logo]()
$521
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/217:30 am -
1 stop8h 25m
Mon 1/2511:50 am -
1 stop10h 28m
Deal found 10/20![Delta logo]()
$443
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:28 am -
1 stop6h 15m
Tue 11/1712:55 pm -
1 stop7h 56m
Deal found 10/24![United Airlines logo]()
$495
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:25 am -
Nonstop3h 45m
Wed 11/182:45 pm -
1 stop7h 05m
Deal found 10/20![Southwest logo]()
$532
This Volaris deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/159:42 am -
1 stop10h 03m
Sun 1/176:45 am -
1 stop9h 42m
Deal found 10/23![Volaris logo]()
$598
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/108:12 am -
1 stop6h 58m
Fri 11/137:00 am -
1 stop10h 41m
Deal found 10/21![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/286:30 am -
2 stops12h 30m
Wed 3/312:27 pm -
2 stops12h 12m
Deal found 10/21![Delta logo]()
$468
This Mytrip deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/74:26 pm -
2 stops24h 24m
Mon 11/97:00 am -
2 stops16h 16m
Deal found 10/20![Multiple Airlines logo]()
$625
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/25:45 am -
1 stop6h 34m
Sat 1/911:51 am -
2 stops9h 55m
Deal found 10/24![United Airlines logo]()
$522
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/295:30 am -
2 stops8h 00m
Thu 12/33:10 pm -
2 stops16h 55m
Deal found 10/20![Southwest logo]()
$557
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/88:37 pm -
2 stops17h 46m
Sat 1/169:45 am -
1 stop26h 50m
Deal found 10/22![Multiple Airlines logo]()
$629
This Delta deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
2 stops13h 00m
Fri 1/2212:05 pm -
2 stops12h 13m
Deal found 10/22![Delta logo]()
$473
This United Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/25:45 am -
1 stop7h 18m
Tue 2/98:39 am -
1 stop6h 39m
Deal found 10/23![United Airlines logo]()
$524
This United Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:36 am -
1 stop29h 51m
Sat 12/123:31 pm -
2 stops20h 59m
Deal found 10/24![United Airlines logo]()
$526
This Southwest deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 2/148:30 am -
2 stops10h 15m
Fri 2/193:00 pm -
1 stop8h 10m
Deal found 10/22![Southwest logo]()
$579
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/216:31 pm -
1 stop15h 29m
Mon 12/2811:59 am -
2 stops10h 39m
Deal found 10/20![American Airlines logo]()
$740
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:00 am -
1 stop7h 22m
Mon 12/143:59 pm -
2 stops16h 51m
Deal found 10/20![Delta logo]()
$510
This Southwest deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/27:25 am -
1 stop8h 30m
Sat 1/912:40 pm -
Nonstop3h 30m
Deal found 10/20![Southwest logo]()
$587
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated October 25, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated October 25, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:30 am -
Nonstop3h 09m
Wed 10/2811:23 am -
Nonstop3h 15m
Deal found 10/21![Volaris logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/97:59 pm -
1 stop20h 51m
Thu 11/125:50 am -
2 stops35h 52m
Deal found 10/23![Multiple Airlines logo]()
$419
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/149:59 am -
2 stops13h 36m
Wed 11/182:04 pm -
1 stop8h 51m
Deal found 10/20![Delta logo]()
$384
This American Airlines deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:44 pm -
1 stop16h 40m
Sat 11/214:22 pm -
1 stop8h 02m
Deal found 10/22![American Airlines logo]()
$385
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:20 am -
Nonstop3h 14m
Tue 11/242:05 pm -
Nonstop3h 20m
Deal found 10/20![Frontier logo]()
$368
This Cheapflightsfares deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:20 am -
Nonstop3h 14m
Fri 11/202:05 pm -
Nonstop3h 20m
Deal found 10/21![Frontier logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:13 am -
1 stop6h 53m
Tue 11/242:05 pm -
Nonstop3h 20m
Deal found 10/20![Multiple Airlines logo]()
$415
This Priceline deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
Nonstop3h 14m
Tue 11/242:05 pm -
Nonstop3h 20m
Deal found 10/20![Frontier logo]()
$371
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/177:05 am -
1 stop8h 20m
Tue 11/244:22 pm -
1 stop8h 02m
Deal found 10/21![American Airlines logo]()
$375
This Justfly.com deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:05 pm -
1 stop25h 40m
Wed 12/27:55 pm -
1 stop20h 33m
Deal found 10/20![Frontier logo]()
$397
This Delta deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/254:00 pm -
2 stops22h 25m
Wed 12/22:04 pm -
1 stop8h 52m
Deal found 10/20![Delta logo]()
$388
This American Airlines deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/298:30 pm -
1 stop16h 22m
Thu 12/31:02 pm -
1 stop8h 01m
Deal found 10/21![American Airlines logo]()
$363
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated October 25, 2026.
This American Airlines deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:20 pm -
1 stop17h 06m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![American Airlines logo]()
$157
This Delta deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/297:20 am -
2 stops12h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![Delta logo]()
$166
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops34h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$166
This American Airlines deal was found by Cheapflights users on 10/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/147:25 pm -
1 stop18h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/23![American Airlines logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 10/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:00 am -
Nonstop3h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/22![Frontier logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:20 am -
Nonstop3h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Frontier logo]()
$174
This Super.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/166:20 am -
Nonstop3h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Frontier logo]()
$175
This Cheapflightsfares deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:20 am -
Nonstop3h 14m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Frontier logo]()
$176
This American Airlines deal was found by Cheapflights users on 10/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:25 pm -
1 stop18h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/20![American Airlines logo]()
$181
This Priceline deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop17h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Frontier logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 10/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/96:34 pm -
2 stops28h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/21![Multiple Airlines logo]()
$184
This Kiwi.com deal was found by Cheapflights users on 10/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/58:32 pm -
1 stop20h 18m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/24![Multiple Airlines logo]()
$188
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated October 25, 2026.
Round-trip from | $318 (American Airlines) |
|---|---|
One-way from | $157 (American Airlines) |
Good round-trip deal | $544 or less |
Good one-way deal | $210 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Mon 3/29
7:20 am-5:48 pm
2 stops12h 28m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$166
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sat 11/14
7:25 pm-12:44 pm
1 stop18h 19m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$170
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Fri 11/13
7:25 pm-12:44 pm
1 stop18h 19m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$181
Kansas CityMexico City
MCI Kansas City - MEX Mexico City Benito Juarez
MCIMEX
Kansas City
Mon 11/16
8:43 pm-4:50 pm
1 stop20h 07m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$190
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sat 1/16
9:59 am-9:14 pm
2 stops12h 15m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$191
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sat 11/14
9:59 am-10:35 pm
2 stops13h 36m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$191
Kansas CityMexico City
MCI Kansas City - MEX Mexico City Benito Juarez
MCIMEX
Kansas City
Sat 1/23
8:31 pm-4:50 pm
1 stop20h 19m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$203
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Fri 12/11
7:54 pm-11:00 pm
2 stops27h 06m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$203
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sat 1/16
8:04 pm-1:01 pm
1 stop17h 57m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$210
St. LouisCancún
STL Lambert-St Louis - CUN Cancun
STLCUN
Lambert-St Louis
Tue 11/17
5:00 am-3:37 pm
2 stops9h 37m
Cancun
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$225
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-SJD
MCI-SJD
MCI-MEX
STL-CUN
STL-PVR
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-SJD
MCI-SJD
MCI-MEX
STL-CUN
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, January is the cheapest month in which you can book a flight from Missouri to Mexico (average of $563). Flying from Missouri to Mexico in December is currently the most expensive (average of $756). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 25, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from Missouri to Mexico?
The price you pay for your flight from Missouri to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 20 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on October 25, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 10 airlines flying from Missouri to Mexico
Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 25, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$183 | Average$609 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$183 | Average$590 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$184 | Average$437 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$207 | Average$459 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$259 | Average$526 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$370 | Average$667 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$383 | Average$702 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$404 | Average$650 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$424 | Average$659 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |