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$102+ Cheap flights from Missouri to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/15. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Oct 17 — Oct 241
Fri 10/17
Fri 10/24
1 adult, Economy
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Cheap flight deals from Missouri to Mexico

Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated September 17, 2025.

Round-trip from

$244
(Cheapflightsfares)

One-way from

$102
(Trip.com)

Popular in

December

Cheapest in

April

Average price

$658

Good round-trip deal

$282 or less

Good one-way deal

$182 or less
From Missouri to Mexico
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One-way flight from Missouri to Mexico
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Highest demand for flights based on searches. 6% potential increase in price ($44 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Price to beat on a round-trip flight from Missouri to Mexico.
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Price to beat on a one-way flight from Missouri to Mexico.
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Find flight deals from Missouri to Mexico

Cheapest flights from Missouri to Mexico
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 17, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:22 amSTL - CUN
Nonstop3h 13mFrontier
Thu 10/162:50 pmCUN - STL
Nonstop3h 17mFrontier
Deal found 9/15$244
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/2410:21 amSTL - CUN
Nonstop3h 13mFrontier
Wed 10/12:49 pmCUN - STL
Nonstop3h 21mFrontier
Deal found 9/16$284
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:52 pmSTL - CUN
1 stop19h 12mFrontier
Thu 10/303:45 pmCUN - STL
Nonstop3h 15mFrontier
Deal found 9/15$294
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:21 amSTL - CUN
Nonstop3h 13mFrontier
Mon 10/62:49 pmCUN - STL
Nonstop3h 21mFrontier
Deal found 9/16$295
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1310:22 amSTL - CUN
Nonstop3h 13mFrontier
Fri 10/172:50 pmCUN - STL
Nonstop3h 17mFrontier
Deal found 9/15$297
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2310:17 amSTL - CUN
1 stop22h 30mMultiple Airlines
Thu 10/303:45 pmCUN - STL
Nonstop3h 15mMultiple Airlines
Deal found 9/14$298
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/1810:22 amSTL - CUN
Nonstop3h 13mMultiple Airlines
Sat 10/259:52 amCUN - STL
1 stop23h 30mMultiple Airlines
Deal found 9/14$301
This Mytrip deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/1510:17 amSTL - CUN
Nonstop3h 13mMultiple Airlines
Fri 11/2110:10 pmCUN - STL
1 stop18h 19mMultiple Airlines
Deal found 9/16$304
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/247:52 pmSTL - CUN
1 stop19h 12mMultiple Airlines
Thu 10/309:52 amCUN - STL
1 stop7h 35mMultiple Airlines
Deal found 9/15$309
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2910:21 amSTL - CUN
Nonstop3h 13mFrontier
Tue 9/302:49 pmCUN - STL
Nonstop3h 21mFrontier
Deal found 9/15$310
This Kiwi.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/3010:21 amSTL - CUN
Nonstop3h 13mFrontier
Fri 10/32:49 pmCUN - STL
Nonstop3h 21mFrontier
Deal found 9/16$311
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:02 pmMCI - CUN
2 stops31h 31mMultiple Airlines
Wed 10/229:09 amCUN - MCI
1 stop11h 36mMultiple Airlines
Deal found 9/15$342

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.

Fly from

Missouri

Fly to

Mexico

Route

Depart

Return

Price

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 9/24

10:21 am-1:34 pm

Nonstop3h 13m

Cancun

Wed 10/1

2:49 pm-6:10 pm

Nonstop3h 21m

$284

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 9/24

1:30 pm-1:00 pm

1 stop23h 30m

Cancun

Wed 10/1

2:49 pm-6:10 pm

Nonstop3h 21m

$321

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 10/15

10:22 am-1:35 pm

Nonstop3h 13m

Cancun

Sun 10/19

2:50 pm-6:07 pm

Nonstop3h 17m

$329

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Thu 12/4

9:30 am-9:20 pm

1 stop10h 50m

Cancun

Tue 12/9

8:00 am-6:34 pm

1 stop11h 34m

$361

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 12/8

11:40 am-9:20 pm

1 stop8h 40m

Cancun

Mon 12/15

8:00 am-5:57 pm

1 stop10h 57m

$361

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sat 11/15

10:17 am-2:30 pm

Nonstop3h 13m

Cancun

Sat 11/22

8:00 am-4:07 pm

1 stop9h 07m

$364

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 9/24

9:15 am-7:40 pm

1 stop10h 25m

Cancun

Wed 10/1

8:45 pm-3:18 pm

1 stop18h 33m

$366

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 10/13

10:22 am-1:35 pm

Nonstop3h 13m

Cancun

Thu 10/16

1:49 pm-12:00 pm

3 stops22h 11m

$369

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Wed 10/1

10:21 am-1:34 pm

Nonstop3h 13m

Cancun

Sun 10/5

1:49 pm-3:04 pm

2 stops25h 15m

$386

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sat 11/1

11:17 am-2:30 pm

Nonstop3h 13m

Cancun

Sat 11/8

11:57 am-11:09 am

1 stop24h 12m

$394

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/16

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mexico

What is the cheapest month to book a flight from Missouri to Mexico?

Currently, May is the cheapest month in which you can book a flight from Missouri to Mexico (average of $387). Flying from Missouri to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MX?

Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 17, 2025.

When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mexico?

    There are many flights that can get you from Missouri to Mexico in 3h 13m. Fly via Frontier, Delta, or American Airlines to get the fastest option. Missouri and Mexico are separated by a distance of 1241 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mexico one-way?

    $113 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on Spirit Airlines and Delta, with prices starting from $173 and $179, respectively.

  • Can I find deals for flights from Missouri to Mexico that include hotel bookings?

    Yes. In addition to deals on Missouri to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mexico.

  • Can I find deals for business class flights from Missouri to Mexico?

    Yes. Cheapflights offers flight deals from Missouri to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mexico?

    Currently, May is the cheapest month in which you can book a flight from Missouri to Mexico (average of $387). Flying from Missouri to Mexico in December is currently the most expensive (average of $615). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to John F Kennedy Intl flights
John F Kennedy Intl to Miami flights
John F Kennedy Intl to Los Angeles flights
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Top 9 airlines flying from Missouri to Mexico

Discover the top 9 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 17, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$130Average$336FlexibilityNo cancel feeOn-time65%
VolarisCheapest$174Average$365FlexibilityNo cancel feeOn-time79%
DeltaCheapest$185Average$585FlexibilityNo cancel feeOn-timeN/A
AeromexicoCheapest$243Average$534FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$256Average$504FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$297Average$616FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$306Average$632FlexibilityNo cancel feeOn-time71%
Alaska AirlinesCheapest$385Average$574FlexibilityNo cancel feeOn-time75%
SouthwestCheapest$453Average$673FlexibilityNo cancel feeOn-time63%

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