$136+ Cheap flights from Missouri to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/4. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Dec 5 — Dec 121
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 5, 2026.
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop13h 55m
Sat 12/57:55 pm -
1 stop20h 45m
Deal found 11/4![Frontier logo]()
$352
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop14h 23m
Wed 12/911:10 am -
1 stop13h 02m
Deal found 11/1![Frontier logo]()
$362
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops34h 53m
Fri 12/118:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$363
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops34h 53m
Tue 12/88:00 am -
1 stop27h 04m
Deal found 11/1![Multiple Airlines logo]()
$368
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop14h 23m
Tue 12/88:00 am -
1 stop27h 04m
Deal found 11/1![Frontier logo]()
$369
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop10h 45m
Mon 12/76:10 am -
1 stop10h 30m
Deal found 11/2![Frontier logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops37h 13m
Fri 12/119:02 am -
1 stop25h 55m
Deal found 11/4![Multiple Airlines logo]()
$372
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/77:00 am -
1 stop7h 22m
Thu 12/102:04 pm -
1 stop8h 52m
Deal found 11/2![Delta logo]()
$372
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop7h 22m
Thu 12/243:17 pm -
1 stop18h 06m
Deal found 11/4![Delta logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:05 pm -
2 stops10h 50m
Fri 12/118:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops34h 53m
Thu 12/108:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:55 am -
1 stop8h 32m
Sat 12/195:19 pm -
1 stop6h 40m
Deal found 11/2![American Airlines logo]()
$380
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 5, 2026.
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop7h 22m
Thu 12/102:27 pm -
1 stop9h 00m
Deal found 11/2![Delta logo]()
$372
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/35:15 pm -
2 stops17h 28m
Tue 2/92:03 pm -
1 stop7h 43m
Deal found 11/3![United Airlines logo]()
$380
This FlightHub deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/277:02 pm -
1 stop22h 26m
Sat 2/278:51 pm -
2 stops37h 29m
Deal found 10/31![Frontier logo]()
$475
This Volaris deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop17h 20m
Thu 12/311:10 am -
1 stop13h 02m
Deal found 10/31![Volaris logo]()
$520
This Southwest deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/239:15 am -
1 stop7h 20m
Sat 1/3012:40 pm -
Nonstop3h 40m
Deal found 11/1![Southwest logo]()
$531
This Kiwi.com deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1512:14 pm -
2 stops28h 06m
Wed 11/189:02 am -
1 stop25h 43m
Deal found 10/30![Multiple Airlines logo]()
$577
This Alaska Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/44:06 pm -
2 stops23h 40m
Mon 2/82:00 pm -
2 stops25h 08m
Deal found 10/31![Alaska Airlines logo]()
$659
This Aeromexico deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/236:00 am -
1 stop14h 50m
Wed 1/278:30 am -
1 stop7h 21m
Deal found 11/2![Aeromexico logo]()
$680
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:02 pm -
2 stops21h 51m
Thu 12/103:59 pm -
2 stops16h 30m
Deal found 11/2![Delta logo]()
$383
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:45 am -
1 stop8h 20m
Thu 1/141:27 pm -
1 stop7h 08m
Deal found 10/31![United Airlines logo]()
$385
This American Airlines deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/168:00 am -
1 stop6h 48m
Sat 2/66:00 am -
1 stop8h 08m
Deal found 11/4![American Airlines logo]()
$780
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/227:00 am -
1 stop8h 25m
Tue 3/29:57 am -
2 stops13h 59m
Deal found 10/31![Delta logo]()
$385
This United Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/205:45 am -
1 stop8h 20m
Tue 1/263:31 pm -
1 stop6h 59m
Deal found 10/31![United Airlines logo]()
$385
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
2 stops12h 39m
Sun 1/243:24 pm -
1 stop7h 02m
Deal found 11/4![Delta logo]()
$392
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:55 am -
2 stops8h 50m
Wed 1/279:40 am -
2 stops12h 00m
Deal found 10/30![Southwest logo]()
$545
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:54 pm -
1 stop21h 34m
Sun 12/207:00 am -
1 stop27h 53m
Deal found 11/1![Multiple Airlines logo]()
$579
This Volaris deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/186:20 am -
1 stop10h 25m
Sat 11/2111:10 am -
1 stop12h 49m
Deal found 11/4![Volaris logo]()
$590
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/169:59 am -
2 stops14h 26m
Tue 3/2311:58 am -
2 stops9h 19m
Deal found 10/31![Delta logo]()
$450
This United Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals ”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/66:00 am -
3 stops28h 43m
Wed 2/103:31 pm -
2 stops17h 10m
Deal found 11/1![United Airlines logo]()
$515
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/185:15 am -
1 stop8h 50m
Sat 2/138:30 am -
2 stops9h 50m
Deal found 11/2![Southwest logo]()
$568
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/298:31 pm -
1 stop20h 19m
Mon 2/1510:55 pm -
2 stops20h 41m
Deal found 11/4![Multiple Airlines logo]()
$587
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/278:29 pm -
1 stop20h 21m
Fri 12/46:05 am -
2 stops13h 28m
Deal found 11/4![Frontier logo]()
$651
This Volaris deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/268:15 am -
1 stop10h 58m
Tue 3/308:02 am -
1 stop10h 34m
Deal found 10/31![Volaris logo]()
$618
This United Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/305:06 pm -
2 stops19h 37m
Sat 2/62:11 pm -
1 stop7h 19m
Deal found 11/2![United Airlines logo]()
$516
This Delta deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/177:00 am -
1 stop8h 49m
Tue 12/222:05 pm -
1 stop8h 32m
Deal found 11/1![Delta logo]()
$503
This Southwest deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/1811:50 am -
Nonstop3h 15m
Tue 2/232:10 pm -
1 stop9h 35m
Deal found 11/2![Southwest logo]()
$616
This Volaris deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/228:15 am -
1 stop10h 58m
Mon 3/298:02 am -
1 stop10h 34m
Deal found 11/4![Volaris logo]()
$620
This FlightHub deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/225:15 pm -
1 stop29h 30m
Tue 12/19:00 am -
1 stop11h 07m
Deal found 11/3![Frontier logo]()
$683
This United Airlines deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/15:15 pm -
2 stops19h 28m
Fri 2/512:49 pm -
2 stops21h 26m
Deal found 10/30![United Airlines logo]()
$517
This Southwest deal was found by Cheapflights users on 10/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/155:05 am -
1 stop10h 55m
Sun 2/212:50 pm -
1 stop8h 50m
Deal found 10/30![Southwest logo]()
$619
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated November 5, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated November 5, 2026 and is based on user searches.
This FlightHub deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop13h 55m
Sat 12/57:55 pm -
1 stop20h 45m
Deal found 11/4![Frontier logo]()
$352
This Frontier deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop10h 45m
Mon 12/76:10 am -
1 stop10h 30m
Deal found 11/2![Frontier logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:05 pm -
2 stops10h 50m
Fri 12/118:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$379
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops34h 53m
Tue 12/88:00 am -
1 stop27h 04m
Deal found 11/1![Multiple Airlines logo]()
$368
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops37h 13m
Fri 12/119:02 am -
1 stop25h 55m
Deal found 11/4![Multiple Airlines logo]()
$372
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop14h 23m
Wed 12/911:10 am -
1 stop13h 02m
Deal found 11/1![Frontier logo]()
$362
This FlightHub deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop14h 23m
Tue 12/88:00 am -
1 stop27h 04m
Deal found 11/1![Frontier logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops34h 53m
Fri 12/118:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$363
This Delta deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:02 pm -
2 stops21h 51m
Thu 12/102:04 pm -
1 stop8h 52m
Deal found 11/2![Delta logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/712:02 pm -
2 stops34h 53m
Thu 12/108:00 am -
1 stop26h 57m
Deal found 11/1![Multiple Airlines logo]()
$380
This Delta deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/87:00 am -
1 stop7h 22m
Tue 12/223:17 pm -
1 stop17h 07m
Deal found 11/4![Delta logo]()
$378
This American Airlines deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/146:55 am -
1 stop8h 32m
Sat 12/195:19 pm -
1 stop6h 40m
Deal found 11/2![American Airlines logo]()
$380
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated November 5, 2026.
This Kiwi.com deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/412:02 pm -
2 stops34h 53m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Multiple Airlines logo]()
$136
This Kiwi.com deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/152:00 pm -
2 stops32h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Multiple Airlines logo]()
$143
This American Airlines deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/246:00 am -
1 stop9h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![American Airlines logo]()
$162
This United Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/245:15 pm -
2 stops17h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![United Airlines logo]()
$167
This Delta deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/109:59 am -
2 stops13h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![Delta logo]()
$170
This American Airlines deal was found by Cheapflights users on 10/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/115:01 am -
2 stops12h 16m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/31![American Airlines logo]()
$171
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/286:00 am -
1 stop8h 25m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$172
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/167:02 pm -
2 stops23h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$172
This Mytrip deal was found by Cheapflights users on 11/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:35 pm -
1 stop14h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/1![Frontier logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:05 pm -
2 stops37h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/4![Multiple Airlines logo]()
$173
This Kiwi.com deal was found by Cheapflights users on 11/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/137:02 pm -
2 stops19h 21m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/2![Multiple Airlines logo]()
$174
This American Airlines deal was found by Cheapflights users on 11/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/127:20 pm -
1 stop18h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/3![American Airlines logo]()
$176
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated November 5, 2026.
Round-trip from | $352 (FlightHub) |
|---|---|
One-way from | $136 (Kiwi.com) |
Good round-trip deal | $551 or less |
Good one-way deal | $242 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Fri 12/4
12:02 pm-10:55 pm
2 stops34h 53m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$136
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Tue 11/24
6:00 am-2:51 pm
1 stop9h 51m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$162
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Mon 12/21
7:05 am-2:12 pm
1 stop8h 07m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$162
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Tue 12/1
6:00 am-3:35 pm
1 stop10h 35m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$162
Kansas CityPuerto Vallarta
MCI Kansas City - PVR Puerto Vallarta Ordaz
MCIPVR
Kansas City
Sun 1/24
5:15 pm-10:43 am
2 stops17h 28m
Puerto Vallarta Ordaz
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$167
Kansas CityPuerto Vallarta
MCI Kansas City - PVR Puerto Vallarta Ordaz
MCIPVR
Kansas City
Mon 1/11
5:01 am-5:17 pm
2 stops12h 16m
Puerto Vallarta Ordaz
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$171
St. LouisGuadalajara
STL Lambert-St Louis - GDL Guadalajara Miguel Hidal
STLGDL
Lambert-St Louis
Wed 12/2
12:05 pm-1:15 am
2 stops37h 10m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$173
St. LouisGuadalajara
STL Lambert-St Louis - GDL Guadalajara Miguel Hidal
STLGDL
Lambert-St Louis
Fri 1/15
7:02 pm-8:38 pm
2 stops49h 36m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$174
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Sat 12/12
5:45 am-2:32 pm
2 stops9h 47m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$187
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Wed 12/2
12:05 pm-4:31 pm
3 stops29h 26m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$195
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-MEX
STL-SJD
MCI-PVR
STL-CUN
MCI-CUN
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-MEX
STL-SJD
MCI-PVR
STL-CUN
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, January is the cheapest month in which you can book a flight from Missouri to Mexico (average of $566). Flying from Missouri to Mexico in December is currently the most expensive (average of $731). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 5, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from Missouri to Mexico?
The price you pay for your flight from Missouri to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 20 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on November 5, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 10 airlines flying from Missouri to Mexico
Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$180 | Average$608 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$183 | Average$590 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$184 | Average$437 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$207 | Average$461 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$259 | Average$526 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$370 | Average$677 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$383 | Average$703 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$424 | Average$659 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$433 | Average$664 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |