$122+ Cheap flights from Missouri to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Mar 19 — Mar 261
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
STL
- CUN
Nonstop3h 17m
Frontier
Wed 5/1311:44 am
CUN
- STL
Nonstop3h 31m
Frontier
Deal found 2/13![Frontier logo]()
$341
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- CUN
1 stop24h 21m
Frontier
Thu 3/269:11 am
CUN
- STL
1 stop21h 51m
Frontier
Deal found 2/16![Frontier logo]()
$342
This Expedia deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:12 pm
STL
- CUN
1 stop18h 27m
Frontier
Sat 5/162:36 pm
CUN
- STL
1 stop8h 43m
Frontier
Deal found 2/15![Frontier logo]()
$348
This Frontier deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- CUN
1 stop11h 44m
Frontier
Tue 3/31:26 pm
CUN
- STL
2 stops18h 25m
Frontier
Deal found 2/13![Frontier logo]()
$353
This Travelocity deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:16 pm
STL
- CUN
1 stop18h 23m
Frontier
Tue 4/214:09 pm
CUN
- STL
1 stop14h 41m
Frontier
Deal found 2/13![Frontier logo]()
$358
This CheapOair deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:13 pm
STL
- CUN
1 stop16h 13m
Frontier
Tue 4/284:09 pm
CUN
- STL
1 stop14h 41m
Frontier
Deal found 2/15![Frontier logo]()
$359
This Frontier deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- CUN
1 stop11h 34m
Frontier
Sat 3/72:22 pm
CUN
- STL
1 stop9h 57m
Frontier
Deal found 2/13![Frontier logo]()
$362
This Priceline deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/188:13 pm
STL
- CUN
1 stop18h 43m
Frontier
Sat 4/252:36 pm
CUN
- STL
1 stop8h 43m
Frontier
Deal found 2/16![Frontier logo]()
$365
This CheapOair deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/1911:21 am
STL
- CUN
1 stop27h 35m
Frontier
Thu 4/234:09 pm
CUN
- STL
1 stop14h 41m
Frontier
Deal found 2/17![Frontier logo]()
$366
This Expedia deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:17 pm
STL
- CUN
1 stop11h 34m
Frontier
Sat 2/289:00 am
CUN
- STL
1 stop15h 59m
Frontier
Deal found 2/14![Frontier logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:55 pm
STL
- MEX
1 stop27h 50m
Multiple Airlines
Sat 4/258:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$369
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:12 pm
STL
- MEX
1 stop22h 18m
Multiple Airlines
Fri 5/18:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$370
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 17, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 17, 2026.
This Delta deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/86:00 am
STL
- CUN
2 stops12h 47m
Delta
Wed 3/1112:28 pm
CUN
- STL
1 stop8h 14m
Delta
Deal found 2/13![Delta logo]()
$386
This Expedia deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:54 pm
STL
- CUN
1 stop27h 15m
Frontier
Fri 3/61:25 pm
CUN
- STL
1 stop18h 37m
Frontier
Deal found 2/16![Frontier logo]()
$393
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:46 am
STL
- SJD
1 stop9h 04m
American Airlines
Fri 4/172:59 pm
SJD
- STL
1 stop15h 55m
American Airlines
Deal found 2/14![American Airlines logo]()
$420
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:13 pm
STL
- MEX
2 stops17h 07m
Multiple Airlines
Fri 5/18:40 am
MEX
- STL
1 stop9h 32m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$423
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:05 am
MCI
- CUN
1 stop8h 32m
United Airlines
Sat 4/187:51 am
CUN
- MCI
1 stop6h 28m
United Airlines
Deal found 2/13![United Airlines logo]()
$435
This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/115:10 am
MCI
- CUN
2 stops7h 50m
Southwest
Wed 4/154:40 pm
CUN
- MCI
2 stops15h 55m
Southwest
Deal found 2/13![Southwest logo]()
$439
This Aeromexico deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:40 am
MCI
- SJD
1 stop9h 24m
Aeromexico
Mon 4/202:00 pm
SJD
- MCI
1 stop7h 57m
Aeromexico
Deal found 2/14![Aeromexico logo]()
$451
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/286:48 am
STL
- CUN
1 stop6h 16m
Delta
Tue 5/512:40 pm
CUN
- STL
1 stop10h 56m
Delta
Deal found 2/16![Delta logo]()
$386
This Delta deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/197:25 am
STL
- CUN
2 stops12h 10m
Delta
Thu 4/238:00 am
CUN
- STL
1 stop7h 32m
Delta
Deal found 2/16![Delta logo]()
$386
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:03 pm
STL
- SJD
1 stop18h 47m
American Airlines
Fri 5/1511:32 am
SJD
- STL
1 stop10h 24m
American Airlines
Deal found 2/14![American Airlines logo]()
$426
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/173:02 pm
STL
- MEX
1 stop8h 43m
Multiple Airlines
Tue 4/2811:05 am
MEX
- STL
1 stop11h 14m
Multiple Airlines
Deal found 2/16![Multiple Airlines logo]()
$427
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/116:35 am
SGF
- CUN
1 stop5h 27m
United Airlines
Tue 8/181:57 pm
CUN
- SGF
2 stops9h 32m
United Airlines
Deal found 2/13![United Airlines logo]()
$440
This Southwest deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/209:35 am
MCI
- CUN
Nonstop3h 15m
Southwest
Sat 4/259:55 am
CUN
- MCI
1 stop7h 50m
Southwest
Deal found 2/16![Southwest logo]()
$440
This Aeromexico deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/1310:43 am
STL
- PVR
2 stops13h 37m
Aeromexico
Mon 5/188:15 pm
PVR
- STL
2 stops18h 55m
Aeromexico
Deal found 2/14![Aeromexico logo]()
$474
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/711:21 am
STL
- MEX
2 stops12h 24m
Multiple Airlines
Fri 5/1511:05 am
MEX
- STL
1 stop11h 14m
Multiple Airlines
Deal found 2/14![Multiple Airlines logo]()
$432
This United Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/126:35 am
SGF
- CUN
1 stop5h 27m
United Airlines
Wed 8/191:57 pm
CUN
- SGF
2 stops10h 48m
United Airlines
Deal found 2/13![United Airlines logo]()
$440
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/107:08 am
SGF
- CUN
1 stop9h 51m
American Airlines
Wed 4/1511:52 am
CUN
- SGF
1 stop10h 46m
American Airlines
Deal found 2/13![American Airlines logo]()
$441
This Delta deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/176:00 am
STL
- CUN
1 stop8h 25m
Delta
Wed 3/2511:05 am
CUN
- STL
2 stops12h 20m
Delta
Deal found 2/15![Delta logo]()
$402
This Frontier deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/83:02 pm
STL
- MEX
1 stop8h 43m
Frontier
Wed 5/1311:05 am
MEX
- STL
1 stop11h 14m
Frontier
Deal found 2/14![Frontier logo]()
$490
This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/126:50 am
MCI
- SJD
1 stop6h 30m
Southwest
Sat 4/189:55 am
SJD
- MCI
Nonstop3h 10m
Southwest
Deal found 2/13![Southwest logo]()
$446
This United Airlines deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:15 pm
STL
- SJD
2 stops16h 15m
United Airlines
Wed 4/811:52 am
SJD
- STL
1 stop7h 16m
United Airlines
Deal found 2/15![United Airlines logo]()
$444
This Delta deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/56:29 am
STL
- CUN
2 stops13h 06m
Delta
Thu 4/94:10 pm
CUN
- STL
1 stop7h 15m
Delta
Deal found 2/17![Delta logo]()
$406
This American Airlines deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/207:15 am
SGF
- CUN
1 stop12h 30m
American Airlines
Tue 3/314:09 pm
CUN
- SGF
1 stop18h 00m
American Airlines
Deal found 2/13![American Airlines logo]()
$448
This Southwest deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 am
MCI
- SJD
Nonstop3h 45m
Southwest
Fri 5/111:40 am
SJD
- MCI
1 stop8h 00m
Southwest
Deal found 2/15![Southwest logo]()
$452
This CheapOair deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/68:12 pm
STL
- PVR
1 stop14h 58m
Frontier
Mon 3/911:58 am
PVR
- STL
2 stops45h 39m
Frontier
Deal found 2/16![Frontier logo]()
$502
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/186:04 pm
MCI
- MEX
1 stop27h 01m
Multiple Airlines
Tue 3/247:00 am
MEX
- MCI
2 stops33h 09m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$461
This Aeromexico deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/161:02 pm
STL
- PVR
2 stops20h 28m
Aeromexico
Tue 4/218:15 pm
PVR
- STL
2 stops20h 29m
Aeromexico
Deal found 2/13![Aeromexico logo]()
$514
This United Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/138:15 pm
STL
- SJD
2 stops16h 15m
United Airlines
Fri 4/173:15 pm
SJD
- STL
1 stop12h 35m
United Airlines
Deal found 2/14![United Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/16:00 am
SGF
- CUN
1 stop6h 14m
American Airlines
Wed 4/88:00 am
CUN
- SGF
1 stop12h 46m
American Airlines
Deal found 2/14![American Airlines logo]()
$454
This Southwest deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/412:20 pm
MCI
- CUN
1 stop7h 55m
Southwest
Thu 4/94:40 pm
CUN
- MCI
1 stop7h 15m
Southwest
Deal found 2/13![Southwest logo]()
$460
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated February 17, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated February 17, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:17 pm
STL
- CUN
1 stop11h 34m
Frontier
Sat 2/289:00 am
CUN
- STL
1 stop15h 59m
Frontier
Deal found 2/14![Frontier logo]()
$369
This Expedia deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/231:54 pm
STL
- CUN
1 stop27h 15m
Frontier
Tue 3/32:27 pm
CUN
- STL
1 stop26h 26m
Frontier
Deal found 2/13![Frontier logo]()
$374
This Expedia deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:24 pm
MCI
- CUN
1 stop18h 53m
Frontier
Mon 3/212:24 pm
CUN
- MCI
1 stop8h 24m
Frontier
Deal found 2/13![Frontier logo]()
$374
This Priceline deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/278:22 pm
STL
- CUN
1 stop11h 44m
Frontier
Tue 3/32:27 pm
CUN
- STL
1 stop26h 26m
Frontier
Deal found 2/13![Frontier logo]()
$348
This Priceline deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/11:44 pm
MCI
- CUN
1 stop26h 33m
Frontier
Tue 3/244:15 pm
CUN
- MCI
1 stop18h 43m
Frontier
Deal found 2/13![Frontier logo]()
$372
This CheapOair deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:54 pm
STL
- CUN
1 stop27h 15m
Frontier
Tue 3/104:09 pm
CUN
- STL
1 stop18h 28m
Frontier
Deal found 2/16![Frontier logo]()
$373
This CheapOair deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/21:54 pm
STL
- CUN
1 stop27h 15m
Frontier
Sat 3/72:22 pm
CUN
- STL
1 stop9h 57m
Frontier
Deal found 2/14![Frontier logo]()
$380
This CheapOair deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/34:24 pm
MCI
- CUN
1 stop15h 54m
Multiple Airlines
Mon 3/169:01 am
CUN
- MCI
1 stop8h 24m
Multiple Airlines
Deal found 2/13![Multiple Airlines logo]()
$379
This Frontier deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/48:17 pm
STL
- CUN
1 stop11h 34m
Frontier
Sat 3/72:22 pm
CUN
- STL
1 stop9h 57m
Frontier
Deal found 2/14![Frontier logo]()
$362
This Expedia deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/114:51 pm
STL
- CUN
1 stop15h 10m
Frontier
Sun 3/1510:08 am
CUN
- STL
1 stop23h 41m
Frontier
Deal found 2/16![Frontier logo]()
$378
This Kiwi.com deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2312:16 pm
STL
- CUN
1 stop24h 21m
Frontier
Thu 3/269:11 am
CUN
- STL
1 stop21h 51m
Frontier
Deal found 2/16![Frontier logo]()
$342
This Frontier deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:27 am
STL
- CUN
2 stops23h 49m
Frontier
Tue 3/3112:31 pm
CUN
- STL
2 stops21h 17m
Frontier
Deal found 2/14![Frontier logo]()
$371
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated February 17, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated February 17, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:00 am
STL
- CUN
Nonstop3h 17m
Frontier
Deal found 2/13![Frontier logo]()
$122
This Expedia deal was found by Cheapflights users on 2/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/98:12 pm
STL
- CUN
1 stop18h 27m
Frontier
Deal found 2/17![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/106:00 am
STL
- CUN
Nonstop3h 17m
Frontier
Deal found 2/13![Frontier logo]()
$131
This Travelocity deal was found by Cheapflights users on 2/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/158:12 pm
STL
- CUN
1 stop18h 27m
Frontier
Deal found 2/16![Frontier logo]()
$160
This Travelocity deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/92:51 pm
MCI
- CUN
1 stop23h 48m
Frontier
Deal found 2/14![Frontier logo]()
$160
This Super.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/254:51 pm
STL
- CUN
1 stop15h 10m
Frontier
Deal found 2/14![Frontier logo]()
$161
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/184:51 pm
STL
- CUN
1 stop15h 10m
Frontier
Deal found 2/13![Frontier logo]()
$163
This Kiwi.com deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:12 pm
STL
- SJD
3 stops39h 57m
Multiple Airlines
Deal found 2/15![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/22:51 pm
MCI
- CUN
1 stop23h 48m
Frontier
Deal found 2/14![Frontier logo]()
$167
This Priceline deal was found by Cheapflights users on 2/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:13 pm
STL
- CUN
1 stop16h 13m
Frontier
Deal found 2/15![Frontier logo]()
$169
This Priceline deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/104:31 pm
MCI
- CUN
1 stop16h 51m
Frontier
Deal found 2/13![Frontier logo]()
$169
This Kiwi.com deal was found by Cheapflights users on 2/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/2411:27 am
STL
- CUN
1 stop27h 32m
Frontier
Deal found 2/13![Frontier logo]()
$170
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated February 17, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $341 (Kiwi.com) |
One-way from | $122 (Kiwi.com) |
Popular in | December |
Cheapest in | September |
Average price | $668 |
Good round-trip deal | $413 or less |
Good one-way deal | $216 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Missouri
Fly to
Mexico
Route
Depart
Return
Price
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Sun 3/8
6:00 am-6:47 pm
2 stops12h 47m
Cancun
Wed 3/11
12:28 pm-8:42 pm
1 stop8h 14m
$386
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Tue 4/28
6:48 am-1:04 pm
1 stop6h 16m
Cancun
Tue 5/5
12:40 pm-11:36 pm
1 stop10h 56m
$386
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Sun 4/19
7:25 am-7:35 pm
2 stops12h 10m
Cancun
Thu 4/23
8:00 am-3:32 pm
1 stop7h 32m
$386
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Mon 3/2
1:54 pm-6:09 pm
1 stop27h 15m
Cancun
Fri 3/6
1:25 pm-7:02 am
1 stop18h 37m
$393
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Tue 3/17
6:00 am-2:25 pm
1 stop8h 25m
Cancun
Wed 3/25
11:05 am-11:25 pm
2 stops12h 20m
$402
St. LouisCancún
STL - CUN
STLCUN
Lambert-St Louis
Sun 4/5
6:29 am-7:35 pm
2 stops13h 06m
Cancun
Thu 4/9
4:10 pm-11:25 pm
1 stop7h 15m
$406
St. LouisSan José del Cabo
STL - SJD
STLSJD
Lambert-St Louis
Mon 4/13
5:46 am-12:50 pm
1 stop9h 04m
San José del Cabo Los Cabos
Fri 4/17
2:59 pm-8:54 am
1 stop15h 55m
$420
St. LouisMexico City
STL - MEX
STLMEX
Lambert-St Louis
Wed 4/15
8:13 pm-12:20 pm
2 stops17h 07m
Mexico City Benito Juarez
Fri 5/1
8:40 am-7:12 pm
1 stop9h 32m
$423
St. LouisSan José del Cabo
STL - SJD
STLSJD
Lambert-St Louis
Sat 5/9
8:03 pm-12:50 pm
1 stop18h 47m
San José del Cabo Los Cabos
Fri 5/15
11:32 am-11:56 pm
1 stop10h 24m
$426
St. LouisMexico City
STL - MEX
STLMEX
Lambert-St Louis
Fri 4/17
3:02 pm-10:45 pm
1 stop8h 43m
Mexico City Benito Juarez
Tue 4/28
11:05 am-11:19 pm
1 stop11h 14m
$427
Showing 1-10 of 60 results
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-CUN
MCI-CUN
STL-SJD
MCI-MEX
MCI-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-CUN
MCI-CUN
STL-SJD
MCI-MEX
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, February is the cheapest month in which you can book a flight from Missouri to Mexico (average of $175). Flying from Missouri to Mexico in April is currently the most expensive (average of $244). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated February 17, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
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Top regions
Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on February 17, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 9 airlines flying from Missouri to Mexico
Discover the top 9 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 17, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$168 | Average$540 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$174 | Average$372 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$179 | Average$585 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$201 | Average$403 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$278 | Average$343 | FlexibilityNo cancel fee | On-time65% | |
| Cheapest$314 | Average$611 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$366 | Average$617 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$419 | Average$637 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |