$156+ Cheap flights from Missouri to Mexico
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/2. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Dec 12 — Dec 191
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 12, 2026.
This FlightHub deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop17h 48m
Mon 12/149:25 pm -
1 stop19h 15m
Deal found 11/11![Frontier logo]()
$374
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:00 am -
1 stop11h 35m
Thu 12/101:14 pm -
1 stop9h 38m
Deal found 11/10![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:20 pm -
1 stop18h 22m
Wed 12/92:20 pm -
1 stop8h 29m
Deal found 11/11![American Airlines logo]()
$388
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:20 am -
2 stops10h 36m
Fri 12/114:52 pm -
1 stop15h 15m
Deal found 11/11![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Fri 1/2911:51 am -
1 stop10h 39m
Deal found 11/9![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:00 am -
1 stop11h 35m
Sat 12/512:29 pm -
1 stop9h 13m
Deal found 11/7![American Airlines logo]()
$402
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Thu 1/2811:51 am -
2 stops9h 55m
Deal found 11/9![United Airlines logo]()
$405
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:20 pm -
1 stop20h 07m
Sat 12/123:50 pm -
1 stop7h 59m
Deal found 11/7![American Airlines logo]()
$406
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:40 am -
1 stop9h 29m
Wed 12/910:16 am -
2 stops12h 12m
Deal found 11/10![Delta logo]()
$409
This FlightHub deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop17h 20m
Tue 12/155:55 am -
2 stops29h 09m
Deal found 11/8![Frontier logo]()
$416
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:17 pm -
1 stop20h 41m
Thu 12/101:58 pm -
1 stop7h 05m
Deal found 11/12![American Airlines logo]()
$417
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:16 pm -
1 stop16h 37m
Mon 12/143:51 pm -
1 stop7h 01m
Deal found 11/7![American Airlines logo]()
$424
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 12, 2026.
This United Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:55 pm -
2 stops17h 48m
Thu 12/102:11 pm -
1 stop7h 20m
Deal found 11/7![United Airlines logo]()
$380
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:30 am -
1 stop7h 40m
Tue 12/152:05 pm -
1 stop8h 05m
Deal found 11/10![Southwest logo]()
$380
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/79:00 am -
2 stops15h 28m
Wed 4/146:07 am -
2 stops15h 11m
Deal found 11/9![Delta logo]()
$380
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/295:29 am -
1 stop9h 57m
Wed 2/32:30 pm -
1 stop8h 25m
Deal found 11/11![American Airlines logo]()
$402
This Volaris deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop17h 20m
Sat 12/56:10 am -
1 stop10h 30m
Deal found 11/7![Volaris logo]()
$519
This CheapOair deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:20 pm -
1 stop23h 49m
Mon 12/216:00 am -
1 stop10h 40m
Deal found 11/11![Multiple Airlines logo]()
$566
This FlightHub deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/308:31 pm -
2 stops17h 52m
Sat 2/66:16 am -
2 stops13h 20m
Deal found 11/9![Frontier logo]()
$579
This Aeromexico deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/126:00 am -
2 stops10h 25m
Mon 2/152:05 pm -
1 stop9h 34m
Deal found 11/10![Aeromexico logo]()
$700
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/97:40 am -
1 stop8h 10m
Wed 12/1611:50 am -
1 stop10h 00m
Deal found 11/9![Southwest logo]()
$388
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/295:59 pm -
1 stop17h 06m
Wed 2/32:11 pm -
1 stop7h 19m
Deal found 11/11![United Airlines logo]()
$392
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
2 stops12h 39m
Sun 1/243:24 pm -
1 stop7h 02m
Deal found 11/9![Delta logo]()
$402
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Fri 1/2911:51 am -
1 stop10h 39m
Deal found 11/9![United Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:05 am -
1 stop8h 48m
Wed 12/96:02 am -
2 stops16h 26m
Deal found 11/8![Delta logo]()
$409
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/76:45 pm -
2 stops18h 21m
Thu 1/283:17 pm -
1 stop8h 27m
Deal found 11/8![United Airlines logo]()
$400
This Delta deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:30 am -
1 stop9h 49m
Thu 1/286:00 am -
2 stops10h 51m
Deal found 11/7![Delta logo]()
$409
This Volaris deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop17h 20m
Fri 12/411:10 am -
1 stop13h 02m
Deal found 11/9![Volaris logo]()
$521
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/16:00 am -
1 stop9h 51m
Thu 12/103:51 pm -
1 stop7h 01m
Deal found 11/11![American Airlines logo]()
$523
This United Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Mon 2/83:31 pm -
2 stops17h 35m
Deal found 11/8![United Airlines logo]()
$405
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/2310:05 am -
2 stops13h 12m
Mon 1/253:24 pm -
1 stop7h 32m
Deal found 11/9![Delta logo]()
$430
This Southwest deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop9h 30m
Sat 12/121:15 pm -
Nonstop3h 20m
Deal found 11/9![Southwest logo]()
$523
This Mytrip deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/78:32 pm -
3 stops27h 18m
Mon 12/147:49 pm -
2 stops23h 46m
Deal found 11/7![Multiple Airlines logo]()
$589
This Volaris deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop17h 20m
Thu 12/176:10 am -
1 stop8h 56m
Deal found 11/10![Volaris logo]()
$543
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/246:04 am -
2 stops12h 35m
Sat 1/3011:55 am -
2 stops10h 44m
Deal found 11/11![Delta logo]()
$434
This Mytrip deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/912:02 pm -
2 stops10h 43m
Wed 12/167:00 am -
2 stops17h 12m
Deal found 11/11![Multiple Airlines logo]()
$613
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1211:00 am -
Nonstop3h 10m
Fri 4/163:50 pm -
1 stop7h 20m
Deal found 11/8![Southwest logo]()
$572
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/235:03 am -
2 stops9h 51m
Wed 3/313:47 pm -
1 stop17h 07m
Deal found 11/11![American Airlines logo]()
$635
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/86:45 pm -
2 stops18h 21m
Thu 1/283:31 pm -
2 stops17h 35m
Deal found 11/9![United Airlines logo]()
$482
This Aeromexico deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/136:00 am -
1 stop6h 51m
Sat 2/1311:17 am -
2 stops12h 22m
Deal found 11/9![Aeromexico logo]()
$711
This Kiwi.com deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/151:30 pm -
1 stop30h 50m
Mon 2/228:00 am -
1 stop11h 36m
Deal found 11/9![Multiple Airlines logo]()
$615
This Volaris deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Volaris is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/228:15 am -
1 stop10h 58m
Mon 3/298:02 am -
1 stop10h 34m
Deal found 11/11![Volaris logo]()
$620
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated November 12, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated November 12, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:00 am -
1 stop11h 35m
Thu 12/101:14 pm -
1 stop9h 38m
Deal found 11/10![American Airlines logo]()
$380
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/15:00 am -
1 stop11h 35m
Sat 12/512:29 pm -
1 stop9h 13m
Deal found 11/7![American Airlines logo]()
$402
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/37:20 pm -
1 stop20h 07m
Sat 12/123:50 pm -
1 stop7h 59m
Deal found 11/7![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/35:17 pm -
1 stop20h 41m
Thu 12/101:58 pm -
1 stop7h 05m
Deal found 11/12![American Airlines logo]()
$417
This FlightHub deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:32 am -
1 stop17h 48m
Mon 12/149:25 pm -
1 stop19h 15m
Deal found 11/11![Frontier logo]()
$374
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/57:20 pm -
1 stop18h 22m
Wed 12/92:20 pm -
1 stop8h 29m
Deal found 11/11![American Airlines logo]()
$388
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/55:40 am -
1 stop9h 29m
Wed 12/910:16 am -
2 stops12h 12m
Deal found 11/10![Delta logo]()
$409
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:20 am -
2 stops10h 36m
Fri 12/114:52 pm -
1 stop15h 15m
Deal found 11/11![American Airlines logo]()
$393
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Fri 1/2911:51 am -
1 stop10h 39m
Deal found 11/9![United Airlines logo]()
$400
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:45 am -
1 stop8h 20m
Thu 1/2811:51 am -
2 stops9h 55m
Deal found 11/9![United Airlines logo]()
$405
This FlightHub deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/96:00 am -
1 stop17h 20m
Tue 12/155:55 am -
2 stops29h 09m
Deal found 11/8![Frontier logo]()
$416
This American Airlines deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/107:16 pm -
1 stop16h 37m
Mon 12/143:51 pm -
1 stop7h 01m
Deal found 11/7![American Airlines logo]()
$424
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated November 12, 2026.
This Priceline deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/26:00 am -
1 stop17h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/9![Frontier logo]()
$156
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
1 stop9h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Delta logo]()
$167
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/137:20 pm -
1 stop18h 22m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/12![American Airlines logo]()
$171
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/212:05 pm -
2 stops37h 10m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$173
This Aeromexico deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/96:00 am -
2 stops12h 39m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Aeromexico logo]()
$177
This United Airlines deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/306:34 pm -
1 stop17h 04m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![United Airlines logo]()
$177
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/135:41 pm -
2 stops22h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Delta logo]()
$181
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/305:20 am -
1 stop10h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![American Airlines logo]()
$182
This American Airlines deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/95:07 pm -
1 stop20h 11m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![American Airlines logo]()
$184
This Delta deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/125:41 pm -
2 stops22h 12m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![Delta logo]()
$187
This Southwest deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/169:15 am -
1 stop7h 20m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Southwest logo]()
$189
This United Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 1/75:45 am -
2 stops9h 47m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/11![United Airlines logo]()
$192
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated November 12, 2026.
Round-trip from | $368 (FlightHub) |
|---|---|
One-way from | $156 (Priceline) |
Good round-trip deal | $539 or less |
Good one-way deal | $240 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Wed 12/2
6:00 am-11:20 pm
1 stop17h 20m
Mexico City Benito Juarez
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$156
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Sun 1/17
5:00 am-2:32 pm
2 stops10h 32m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$167
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Mon 1/18
6:15 am-11:43 am
1 stop6h 28m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$167
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Wed 1/20
8:45 am-2:42 pm
1 stop6h 57m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$171
St. LouisGuadalajara
STL Lambert-St Louis - GDL Guadalajara Miguel Hidal
STLGDL
Lambert-St Louis
Wed 12/2
12:05 pm-1:15 am
2 stops37h 10m
Guadalajara Miguel Hidal
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$173
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Wed 3/10
6:00 am-5:39 pm
2 stops12h 39m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$177
Kansas CityPuerto Vallarta
MCI Kansas City - PVR Puerto Vallarta Ordaz
MCIPVR
Kansas City
Wed 12/30
6:34 pm-11:38 am
1 stop17h 04m
Puerto Vallarta Ordaz
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$177
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Tue 1/19
5:49 pm-12:18 pm
1 stop19h 29m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$181
Kansas CitySan José del Cabo
MCI Kansas City - SJD San José del Cabo Los Cabos
MCISJD
Kansas City
Mon 1/18
5:29 pm-5:39 pm
2 stops25h 10m
San José del Cabo Los Cabos
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$181
Kansas CityPuerto Vallarta
MCI Kansas City - PVR Puerto Vallarta Ordaz
MCIPVR
Kansas City
Wed 12/30
5:20 am-3:31 pm
1 stop10h 11m
Puerto Vallarta Ordaz
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$182
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-SJD
STL-MEX
STL-GDL
MCI-GDL
MCI-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-SJD
STL-MEX
STL-GDL
MCI-GDL
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, January is the cheapest month in which you can book a flight from Missouri to Mexico (average of $569). Flying from Missouri to Mexico in December is currently the most expensive (average of $740). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from Missouri to Mexico?
The price you pay for your flight from Missouri to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 20 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on November 12, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 10 airlines flying from Missouri to Mexico
Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$180 | Average$604 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$183 | Average$557 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$185 | Average$488 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$207 | Average$463 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$259 | Average$526 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$370 | Average$676 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$383 | Average$700 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$424 | Average$658 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$433 | Average$723 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |