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$122+ Cheap flights from Missouri to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/17. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — MEX
Jan 14 — Jan 211
Wed 1/14
Wed 1/21
1 adult, Economy
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Cheap flight deals from Missouri to Mexico

Cheapest flights from Missouri to Mexico
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 15, 2025.

This American Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:16 amSGF - CUN
1 stop6h 38mAmerican Airlines
Tue 12/238:45 amCUN - SGF
1 stop9h 45mAmerican Airlines
Deal found 12/13$361
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/134:25 pmSTL - CUN
1 stop19h 02mDelta
Thu 12/1811:09 amCUN - STL
1 stop5h 57mDelta
Deal found 12/13$365
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:20 amSTL - PVR
1 stop8h 55mDelta
Wed 12/313:00 pmPVR - STL
1 stop7h 16mDelta
Deal found 12/13$380
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/246:05 amSTL - CUN
1 stop8h 15mDelta
Wed 12/318:00 amCUN - STL
1 stop12h 04mDelta
Deal found 12/13$389
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/157:00 amSTL - CUN
1 stop9h 54mAmerican Airlines
Sat 12/2012:33 pmCUN - STL
Nonstop3h 35mAmerican Airlines
Deal found 12/14$400
This American Airlines deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/307:46 pmMCI - CUN
1 stop15h 06mAmerican Airlines
Sat 2/286:58 pmCUN - MCI
1 stop14h 57mAmerican Airlines
Deal found 12/14$402
This Delta deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/227:00 amSTL - CZM
1 stop7h 15mDelta
Wed 12/313:30 pmCZM - STL
1 stop8h 08mDelta
Deal found 12/13$403
This Air Canada deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Air Canada is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:05 pmSTL - CUN
1 stop17h 45mAir Canada
Wed 1/77:25 pmCUN - STL
1 stop21h 04mAir Canada
Deal found 12/15$407
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:15 amSTL - CUN
1 stop6h 19mUnited Airlines
Sat 12/208:15 amCUN - STL
1 stop10h 39mUnited Airlines
Deal found 12/13$410
This Delta deal was found by Cheapflights users on 12/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2010:55 amMCI - CUN
Nonstop3h 25mDelta
Thu 12/251:10 pmCUN - MCI
1 stop11h 01mDelta
Deal found 12/14$410
This United Airlines deal was found by Cheapflights users on 12/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/1610:00 amSTL - CUN
2 stops9h 18mUnited Airlines
Sat 12/204:51 pmCUN - STL
1 stop6h 04mUnited Airlines
Deal found 12/13$414
This Delta deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/156:38 pmMCI - CUN
1 stop15h 17mDelta
Sat 12/204:20 pmCUN - MCI
Nonstop3h 40mDelta
Deal found 12/15$414

Find flight deals from Missouri to Mexico

Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated December 15, 2025.

Most accurate provider

CheapOair
3 stars

Most trusted provider

CheapOair
3 stars

Round-trip from

$286
(Kiwi.com)

One-way from

$122
(Trip.com)

Popular in

December

Cheapest in

September

Average price

$820

Good round-trip deal

$346 or less

Good one-way deal

$213 or less
Provider with most accurate pricing for Lambert-St Louis-Mexico City Benito Juarez flight deals.
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Provider most trusted by Cheapflights users for Lambert-St Louis-Mexico City Benito Juarez flights.
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From Missouri to Mexico
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One-way flight from Missouri to Mexico
Search Deals
Highest demand for flights based on searches. 5% potential increase in price ($35 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($17 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
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Price to beat on a round-trip flight from Missouri to Mexico.
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Price to beat on a one-way flight from Missouri to Mexico.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.

Fly from

Missouri

Fly to

Mexico

Route

Depart

Return

Price

St. LouisMexico City

STL - MEX

STLMEX

Lambert-St Louis

Wed 1/28

3:46 pm-10:00 pm

2 stops30h 14m

Mexico City Benito Juarez

Wed 2/4

11:10 am-11:33 pm

1 stop12h 23m

$356

SpringfieldCancún

SGF - CUN

SGFCUN

Springfield-Branson

Wed 1/28

7:00 am-3:25 pm

1 stop7h 25m

Cancun

Wed 2/4

2:25 pm-9:00 pm

1 stop7h 35m

$367

Kansas CityMexico City

MCI - MEX

MCIMEX

Kansas City

Mon 1/19

8:27 pm-5:05 pm

1 stop20h 38m

Mexico City Benito Juarez

Sun 2/8

8:10 am-7:51 pm

1 stop11h 41m

$367

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 3/23

6:10 am-3:15 pm

1 stop9h 05m

Cancun

Thu 3/26

4:30 pm-8:44 am

1 stop16h 14m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Tue 1/13

8:05 am-5:50 pm

2 stops8h 45m

Cancun

Fri 1/16

4:51 pm-10:00 pm

1 stop6h 09m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 1/12

6:00 am-4:35 pm

1 stop9h 35m

Cancun

Thu 1/15

1:43 pm-8:43 pm

1 stop8h 00m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Mon 1/19

9:59 am-4:35 pm

1 stop5h 36m

Cancun

Fri 1/30

8:00 am-2:49 pm

1 stop7h 49m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Tue 1/20

8:05 am-3:35 pm

1 stop6h 30m

Cancun

Tue 1/27

8:39 am-3:52 pm

1 stop8h 13m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sun 4/19

6:30 am-2:04 pm

1 stop7h 34m

Cancun

Thu 4/23

12:35 pm-11:38 pm

1 stop11h 03m

$371

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sun 2/1

7:10 am-3:30 pm

1 stop7h 20m

Cancun

Wed 2/4

11:18 am-11:25 pm

2 stops13h 07m

$371

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/14

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mexico

What is the cheapest month to book a flight from Missouri to Mexico?

Currently, February is the cheapest month in which you can book a flight from Missouri to Mexico (average of $158). Flying from Missouri to Mexico in June is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MX?

Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 15, 2025.

When flying from Missouri to Mexico, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 16% versus a flight in the morning.

What is the cheapest day to fly from Missouri to Mexico?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mexico. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Mexico flight should consider departing on Thursday afternoons when fares are most often at their lowest. Monday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mexico?

    There are many flights that can get you from Missouri to Mexico in 7h 25m. Fly via American Airlines, Delta, or United Airlines to get the fastest option. Missouri and Mexico are separated by a distance of 1185 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mexico one-way?

    $142 is the cheapest one-way deal found within the past few days, from Frontier. You may also be able to find cheap deals on American Airlines and United Airlines, with prices starting from $164 and $173, respectively.

  • Can I find deals for flights from Missouri to Mexico that include hotel bookings?

    Yes. In addition to deals on Missouri to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mexico.

  • Can I find deals for business class flights from Missouri to Mexico?

    Yes. Cheapflights offers flight deals from Missouri to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mexico?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Mexico (average of $158). Flying from Missouri to Mexico in June is currently the most expensive (average of $231). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 9 airlines flying from Missouri to Mexico

Discover the top 9 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 15, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$130Average$326FlexibilityNo cancel feeOn-time65%
VolarisCheapest$175Average$372FlexibilityNo cancel feeOn-time79%
DeltaCheapest$179Average$596FlexibilityNo cancel feeOn-timeN/A
AeromexicoCheapest$218Average$558FlexibilityNo cancel feeOn-timeN/A
FrontierCheapest$232Average$457FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$363Average$614FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$365Average$622FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$419Average$649FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$490Average$609FlexibilityNo cancel feeOn-time75%

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