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$121+ Cheap flights from Missouri to Mexico

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/8. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Apr 28 — May 51
Tue 4/28
Tue 5/5
1 adult, Economy
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Cheap flight deals from Missouri to Mexico

Cheapest flights from Missouri to Mexico
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 29, 2026.

This Justfly.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:16 pm
STL
-
CUN
1 stop15h 08m
Frontier
Sat 4/119:12 am
CUN
-
STL
1 stop14h 13m
Frontier
Deal found 3/25$335
This FlightHub deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/158:23 pm
STL
-
CUN
1 stop18h 33m
Frontier
Sat 4/182:36 pm
CUN
-
STL
1 stop8h 43m
Frontier
Deal found 3/26$336
This Frontier deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/48:17 pm
STL
-
CUN
2 stops17h 50m
Frontier
Fri 5/81:14 pm
CUN
-
STL
2 stops19h 41m
Frontier
Deal found 3/25$342
This FlightHub deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/96:29 pm
STL
-
CUN
2 stops13h 42m
Frontier
Mon 4/139:12 am
CUN
-
STL
1 stop14h 13m
Frontier
Deal found 3/25$345
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/268:08 pm
STL
-
CUN
1 stop15h 56m
Frontier
Sun 5/313:39 pm
CUN
-
STL
1 stop27h 44m
Frontier
Deal found 3/25$346
This FlightHub deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/248:23 pm
STL
-
CUN
1 stop16h 23m
Frontier
Tue 4/2811:48 am
CUN
-
STL
Nonstop3h 31m
Frontier
Deal found 3/27$348
This FlightHub deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/511:21 am
STL
-
CUN
1 stop20h 33m
Frontier
Thu 4/910:13 am
CUN
-
STL
1 stop23h 35m
Frontier
Deal found 3/25$349
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/258:17 pm
STL
-
MEX
1 stop22h 13m
Multiple Airlines
Sat 5/28:40 am
MEX
-
STL
1 stop9h 52m
Multiple Airlines
Deal found 3/28$349
This FlightHub deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:06 pm
STL
-
CUN
1 stop18h 33m
Frontier
Tue 4/2111:48 am
CUN
-
STL
Nonstop3h 31m
Frontier
Deal found 3/26$351
This CheapOair deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/144:05 pm
STL
-
CUN
1 stop24h 35m
Multiple Airlines
Tue 4/214:07 pm
CUN
-
STL
1 stop14h 43m
Multiple Airlines
Deal found 3/25$352
This FlightHub deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:27 am
STL
-
CUN
1 stop24h 54m
Frontier
Sat 4/119:12 am
CUN
-
STL
1 stop14h 13m
Frontier
Deal found 3/25$353
This FlightHub deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/196:00 am
STL
-
CUN
Nonstop3h 17m
Frontier
Thu 4/234:07 pm
CUN
-
STL
1 stop14h 43m
Frontier
Deal found 3/27$354

Find flight deals from Missouri to Mexico

Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated March 29, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$335
(FlightHub)

One-way from

$121
(Expedia)

Popular in

December

Cheapest in

September

Average price

$667

Good round-trip deal

$428 or less

Good one-way deal

$309 or less
Provider with most accurate pricing for Lambert-St Louis-Mexico City Benito Juarez flight deals.
Search Deals
Provider most trusted by Cheapflights users for Lambert-St Louis-Mexico City Benito Juarez flights.
Search Deals
From Missouri to Mexico
Search Deals
One-way flight from Missouri to Mexico
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($96 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($20 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals
Price to beat on a round-trip flight from Missouri to Mexico.
Search Deals
Price to beat on a one-way flight from Missouri to Mexico.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sun 5/31

10:49 am-8:16 pm

1 stop9h 27m

Cancun

Fri 6/5

12:25 pm-11:59 pm

2 stops11h 34m

$377

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Tue 4/14

6:00 am-4:38 pm

2 stops10h 38m

Cancun

Tue 4/21

9:12 am-9:19 pm

2 stops12h 07m

$377

St. LouisCancún

STL - CUN

STLCUN

Lambert-St Louis

Sun 4/19

6:00 am-12:40 pm

1 stop6h 40m

Cancun

Thu 4/23

8:06 am-9:19 pm

2 stops13h 13m

$377

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Sun 4/19

7:00 am-1:04 pm

1 stop8h 04m

San José del Cabo Los Cabos

Tue 4/28

12:34 pm-11:01 pm

1 stop8h 27m

$388

St. LouisMexico City

STL - MEX

STLMEX

Lambert-St Louis

Mon 4/20

3:21 pm-10:45 pm

1 stop8h 24m

Mexico City Benito Juarez

Wed 4/22

8:45 pm-3:19 pm

1 stop17h 34m

$397

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Mon 5/18

2:57 pm-12:30 pm

2 stops23h 33m

San José del Cabo Los Cabos

Wed 5/27

1:35 pm-11:59 pm

1 stop8h 24m

$407

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Fri 4/17

8:05 am-12:48 pm

1 stop6h 43m

San José del Cabo Los Cabos

Tue 4/21

1:17 pm-11:32 pm

1 stop8h 15m

$422

Kansas CitySan José del Cabo

MCI - SJD

MCISJD

Kansas City

Fri 5/1

6:15 am-10:30 am

1 stop6h 15m

San José del Cabo Los Cabos

Tue 5/5

1:44 pm-10:29 pm

1 stop6h 45m

$422

SpringfieldCancún

SGF - CUN

SGFCUN

Springfield-Branson

Sun 6/7

6:58 pm-11:25 am

1 stop16h 27m

Cancun

Wed 6/10

6:00 am-10:09 pm

2 stops16h 09m

$425

Kansas CityPuerto Vallarta

MCI - PVR

MCIPVR

Kansas City

Sun 5/10

8:05 am-7:20 pm

2 stops12h 15m

Puerto Vallarta Ordaz

Thu 5/14

8:33 pm-4:08 pm

2 stops18h 35m

$426

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/27

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Mexico

Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mexico

What is the cheapest month to book a flight from Missouri to Mexico?

Currently, October is the cheapest month in which you can book a flight from Missouri to Mexico (average of $186). Flying from Missouri to Mexico in April is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MX?

Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 29, 2026.

When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mexico?

    There are many flights that can get you from Missouri to Mexico in 6h 43m. Fly via Delta, Frontier, or United Airlines to get the fastest option. Missouri and Mexico are separated by a distance of 1420 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mexico one-way?

    $98 is the cheapest one-way deal found within the past few days, from American Airlines. You may also be able to find cheap deals on Delta and Southwest, with prices starting from $105 and $138, respectively.

  • Can I find deals for flights from Missouri to Mexico that include hotel bookings?

    Yes. In addition to deals on Missouri to Mexico flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mexico?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mexico.

  • Can I find deals for business class flights from Missouri to Mexico?

    Yes. Cheapflights offers flight deals from Missouri to Mexico by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mexico?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Mexico (average of $186). Flying from Missouri to Mexico in April is currently the most expensive (average of $292). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mexico

See prices for flight routes from nearby airports that may be better suited for you.
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Top 10 airlines flying from Missouri to Mexico

Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
AeromexicoCheapest$168Average$524FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$172Average$357FlexibilityNo cancel feeOn-time65%
DeltaCheapest$174Average$589FlexibilityNo cancel feeOn-timeN/A
VolarisCheapest$180Average$375FlexibilityNo cancel feeOn-time79%
FrontierCheapest$213Average$455FlexibilityNo cancel feeOn-time62%
United AirlinesCheapest$278Average$602FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$368Average$614FlexibilityNo cancel feeOn-time71%
JetBlueCheapest$404Average$468FlexibilityNo cancel feeOn-time62%
SouthwestCheapest$419Average$619FlexibilityNo cancel feeOn-time63%
Alaska AirlinesCheapest$527Average$597FlexibilityNo cancel feeOn-time75%

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