$160+ Cheap flights from Missouri to Mexico
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — MEX
Sep 22 — Sep 291
Round-trip
1 adult, Economy
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Find cheap flights from Missouri to Mexico with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Missouri to Mexico
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Cheapest flights from Missouri to MexicoExplore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
Explore the most affordable flight options available from Missouri to Mexico. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 23, 2026.
This Priceline deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/68:32 pm -
1 stop21h 58m
Tue 10/138:40 am -
1 stop10h 08m
Deal found 8/21![Frontier logo]()
$384
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:10 am -
1 stop14h 45m
Sat 11/712:05 pm -
1 stop10h 34m
Deal found 8/19![Frontier logo]()
$387
This FlightHub deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:43 pm -
1 stop20h 17m
Sat 11/218:00 am -
1 stop11h 23m
Deal found 8/21![Frontier logo]()
$398
This FlightHub deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:32 pm -
1 stop21h 58m
Wed 9/308:40 am -
1 stop9h 57m
Deal found 8/18![Frontier logo]()
$399
This Justfly.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/512:14 pm -
1 stop10h 31m
Tue 11/107:55 pm -
1 stop18h 51m
Deal found 8/23![Frontier logo]()
$403
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:43 pm -
1 stop21h 47m
Fri 10/168:40 am -
1 stop10h 08m
Deal found 8/22![Multiple Airlines logo]()
$404
This Frontier deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:17 pm -
1 stop10h 28m
Tue 10/137:55 pm -
2 stops18h 29m
Deal found 8/21![Frontier logo]()
$406
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:20 am -
1 stop13h 25m
Mon 10/127:00 am -
1 stop8h 58m
Deal found 8/20![Frontier logo]()
$414
This Justfly.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:43 pm -
1 stop21h 47m
Thu 10/228:40 am -
1 stop10h 08m
Deal found 8/20![Frontier logo]()
$415
This Justfly.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:10 pm -
2 stops27h 05m
Mon 10/127:00 am -
1 stop8h 58m
Deal found 8/22![Frontier logo]()
$416
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/52:29 pm -
2 stops32h 46m
Wed 10/148:45 pm -
1 stop16h 40m
Deal found 8/20![Multiple Airlines logo]()
$417
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:15 am -
1 stop6h 28m
Fri 12/42:11 pm -
1 stop6h 55m
Deal found 8/19![United Airlines logo]()
$421
Best flights from Missouri to MexicoDiscover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
Discover carefully curated flight deals from Missouri to Mexico that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 23, 2026.
This FlightHub deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:19 pm -
2 stops31h 26m
Wed 10/218:45 pm -
1 stop16h 40m
Deal found 8/19![Frontier logo]()
$429
This United Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:15 am -
1 stop6h 15m
Tue 10/2711:55 am -
1 stop7h 45m
Deal found 8/18![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:10 pm -
1 stop16h 42m
Wed 10/2111:57 am -
2 stops9h 45m
Deal found 8/18![American Airlines logo]()
$436
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/22:29 pm -
2 stops33h 16m
Fri 10/97:00 am -
1 stop9h 46m
Deal found 8/18![Multiple Airlines logo]()
$446
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 1/176:00 am -
1 stop7h 25m
Sun 1/2410:30 am -
2 stops12h 09m
Deal found 8/22![Delta logo]()
$476
This Southwest deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/411:45 am -
1 stop7h 00m
Wed 11/118:20 am -
2 stops8h 15m
Deal found 8/22![Southwest logo]()
$493
This Aeromexico deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:00 am -
2 stops16h 45m
Wed 10/218:00 am -
2 stops12h 23m
Deal found 8/18![Aeromexico logo]()
$599
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/306:15 am -
1 stop6h 28m
Fri 12/42:20 pm -
2 stops17h 28m
Deal found 8/19![United Airlines logo]()
$431
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/235:27 pm -
1 stop20h 00m
Thu 1/2812:58 pm -
1 stop9h 36m
Deal found 8/21![American Airlines logo]()
$437
This CheapOair deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/108:43 pm -
1 stop21h 47m
Fri 10/168:40 am -
1 stop10h 08m
Deal found 8/22![Multiple Airlines logo]()
$467
This Delta deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:25 pm -
1 stop5h 30m
Thu 10/1511:32 am -
2 stops12h 22m
Deal found 8/23![Delta logo]()
$484
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:25 am -
Nonstop3h 15m
Sat 10/2410:50 am -
Nonstop3h 05m
Deal found 8/21![Southwest logo]()
$504
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 1/16:58 pm -
1 stop17h 00m
Thu 1/72:11 pm -
1 stop6h 55m
Deal found 8/22![United Airlines logo]()
$466
This Delta deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/46:15 am -
2 stops12h 33m
Thu 10/812:35 pm -
1 stop11h 19m
Deal found 8/22![Delta logo]()
$488
This Frontier deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/56:05 pm -
2 stops16h 40m
Wed 12/96:00 am -
2 stops12h 54m
Deal found 8/18![Frontier logo]()
$559
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/188:50 pm -
2 stops16h 50m
Fri 9/251:40 pm -
1 stop8h 15m
Deal found 8/19![Southwest logo]()
$523
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/156:15 am -
2 stops12h 34m
Tue 9/2211:30 am -
2 stops12h 12m
Deal found 8/19![Delta logo]()
$488
This United Airlines deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/106:28 am -
1 stop6h 15m
Tue 11/242:11 pm -
2 stops17h 47m
Deal found 8/22![United Airlines logo]()
$494
This Aeromexico deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/187:20 am -
2 stops15h 20m
Sun 2/216:30 am -
2 stops11h 31m
Deal found 8/20![Aeromexico logo]()
$599
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/187:45 am -
2 stops8h 40m
Thu 2/256:25 pm -
1 stop6h 15m
Deal found 8/20![Southwest logo]()
$533
This Delta deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/159:59 am -
2 stops13h 31m
Fri 11/203:40 pm -
2 stops16h 39m
Deal found 8/19![Delta logo]()
$494
This United Airlines deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/158:35 am -
1 stop6h 02m
Tue 9/227:51 am -
1 stop15h 47m
Deal found 8/19![United Airlines logo]()
$508
This American Airlines deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/125:20 am -
1 stop10h 33m
Tue 1/192:35 pm -
1 stop9h 24m
Deal found 8/23![American Airlines logo]()
$616
This Southwest deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/136:45 am -
2 stops8h 30m
Tue 11/1712:35 pm -
2 stops7h 45m
Deal found 8/19![Southwest logo]()
$536
This Aeromexico deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Aeromexico is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/106:00 am -
2 stops10h 55m
Fri 10/167:00 am -
2 stops15h 56m
Deal found 8/22![Aeromexico logo]()
$675
This Delta deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/512:04 pm -
1 stop8h 06m
Wed 12/911:21 am -
2 stops12h 59m
Deal found 8/18![Delta logo]()
$518
This United Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/26:15 am -
1 stop6h 28m
Tue 11/32:11 pm -
1 stop7h 15m
Deal found 8/20![United Airlines logo]()
$551
This Southwest deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/67:00 am -
2 stops7h 55m
Mon 1/1112:00 pm -
2 stops8h 20m
Deal found 8/21![Southwest logo]()
$558
This Delta deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/257:04 am -
1 stop12h 51m
Sat 10/3112:26 pm -
2 stops11h 30m
Deal found 8/20![Delta logo]()
$518
This Southwest deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/245:25 am -
1 stop8h 40m
Sat 10/3111:35 am -
Nonstop3h 25m
Deal found 8/20![Southwest logo]()
$563
Last-minute flights from Missouri to MexicoDiscover last-minute flight deals from Missouri to Mexico. Data last updated August 23, 2026 and is based on user searches.
Discover last-minute flight deals from Missouri to Mexico. Data last updated August 23, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:32 pm -
1 stop21h 58m
Thu 9/178:40 am -
1 stop9h 57m
Deal found 8/21![Multiple Airlines logo]()
$434
This Justfly.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/168:10 pm -
2 stops27h 35m
Wed 9/238:40 am -
1 stop9h 37m
Deal found 8/19![Frontier logo]()
$422
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:32 pm -
1 stop21h 58m
Thu 9/248:40 am -
1 stop9h 57m
Deal found 8/20![Frontier logo]()
$421
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:20 am -
1 stop13h 25m
Tue 9/224:10 pm -
2 stops26h 07m
Deal found 8/20![Frontier logo]()
$439
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
2 stops32h 46m
Wed 9/308:40 am -
1 stop9h 37m
Deal found 8/22![Multiple Airlines logo]()
$425
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
2 stops32h 46m
Sat 9/268:40 am -
1 stop9h 37m
Deal found 8/22![Multiple Airlines logo]()
$428
This Justfly.com deal was found by Cheapflights users on 8/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Justfly.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:32 pm -
1 stop21h 58m
Wed 9/308:40 am -
1 stop9h 57m
Deal found 8/23![Frontier logo]()
$399
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops32h 46m
Wed 9/308:40 am -
1 stop9h 37m
Deal found 8/22![Multiple Airlines logo]()
$419
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/238:10 pm -
1 stop22h 20m
Tue 9/296:20 am -
2 stops29h 50m
Deal found 8/22![Multiple Airlines logo]()
$427
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops30h 16m
Sat 9/268:40 am -
1 stop9h 37m
Deal found 8/22![Multiple Airlines logo]()
$435
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/2410:20 am -
1 stop13h 25m
Thu 10/111:05 am -
2 stops25h 05m
Deal found 8/22![Multiple Airlines logo]()
$438
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
2 stops32h 46m
Wed 10/78:45 pm -
1 stop16h 40m
Deal found 8/21![Multiple Airlines logo]()
$424
One-way flights from Missouri to MexicoSearch for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
Search for one-way flight options from Missouri to Mexico. Find affordable one-way fares based on user searches. Data last updated August 23, 2026.
This American Airlines deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/185:25 am -
1 stop10h 57m
Deal found 8/18![American Airlines logo]()
$160
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:29 pm -
2 stops32h 46m
Deal found 8/22![Multiple Airlines logo]()
$177
This Kiwi.com deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/92:29 pm -
2 stops32h 46m
Deal found 8/20![Multiple Airlines logo]()
$180
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
2 stops32h 46m
Deal found 8/22![Multiple Airlines logo]()
$181
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/168:10 pm -
2 stops26h 47m
Deal found 8/18![Multiple Airlines logo]()
$183
This Kiwi.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/142:29 pm -
2 stops33h 16m
Deal found 8/19![Multiple Airlines logo]()
$183
This Booking.com deal was found by Cheapflights users on 8/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:30 am -
Nonstop3h 09m
Deal found 8/19![Frontier logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/177:42 pm -
2 stops28h 16m
Deal found 8/21![Multiple Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/252:29 pm -
2 stops32h 46m
Deal found 8/22![Multiple Airlines logo]()
$187
This FlightHub deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:30 am -
Nonstop3h 09m
Deal found 8/20![Frontier logo]()
$188
This Priceline deal was found by Cheapflights users on 8/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:20 am -
1 stop13h 25m
Deal found 8/22![Frontier logo]()
$188
This Kiwi.com deal was found by Cheapflights users on 8/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/212:29 pm -
3 stops44h 50m
Deal found 8/18![Multiple Airlines logo]()
$189
Find flight deals from Missouri to Mexico
Keep the following information in mind while searching for Missouri to Mexico flight deals. Data was last updated August 23, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $384 (Priceline) |
One-way from | $160 (American Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $700 |
Good round-trip deal | $554 or less |
Good one-way deal | $256 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Missouri to Mexico that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
Use the filters below to find and compare flights from Missouri to Mexico that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Wed 10/14
4:19 pm-10:45 pm
2 stops31h 26m
Mexico City Benito Juarez
Wed 10/21
8:45 pm-2:25 pm
1 stop16h 40m
$429
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Tue 10/20
6:15 am-10:30 am
1 stop6h 15m
San José del Cabo Los Cabos
Tue 10/27
11:55 am-9:40 pm
1 stop7h 45m
$431
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Mon 11/30
6:15 am-11:43 am
1 stop6h 28m
San José del Cabo Los Cabos
Fri 12/4
2:20 pm-8:48 am
2 stops17h 28m
$431
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Sat 10/17
7:10 pm-9:52 am
1 stop16h 42m
San José del Cabo Los Cabos
Wed 10/21
11:57 am-11:42 pm
2 stops9h 45m
$436
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Sat 1/23
5:27 pm-12:27 pm
1 stop20h 00m
San José del Cabo Los Cabos
Thu 1/28
12:58 pm-11:34 pm
1 stop9h 36m
$437
St. LouisMexico City
STL Lambert-St Louis - MEX Mexico City Benito Juarez
STLMEX
Lambert-St Louis
Fri 10/2
2:29 pm-10:45 pm
2 stops33h 16m
Mexico City Benito Juarez
Fri 10/9
7:00 am-5:46 pm
1 stop9h 46m
$446
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Fri 1/1
6:58 pm-10:58 am
1 stop17h 00m
San José del Cabo Los Cabos
Thu 1/7
2:11 pm-10:06 pm
1 stop6h 55m
$466
Kansas CityMexico City
MCI Kansas City - MEX Mexico City Benito Juarez
MCIMEX
Kansas City
Sat 10/10
8:43 pm-5:30 pm
1 stop21h 47m
Mexico City Benito Juarez
Fri 10/16
8:40 am-7:48 pm
1 stop10h 08m
$467
St. LouisSan José del Cabo
STL Lambert-St Louis - SJD San José del Cabo Los Cabos
STLSJD
Lambert-St Louis
Sun 1/17
6:00 am-12:25 pm
1 stop7h 25m
San José del Cabo Los Cabos
Sun 1/24
10:30 am-11:39 pm
2 stops12h 09m
$476
St. LouisCancún
STL Lambert-St Louis - CUN Cancun
STLCUN
Lambert-St Louis
Tue 10/6
2:25 pm-7:55 pm
1 stop5h 30m
Cancun
Thu 10/15
11:32 am-11:54 pm
2 stops12h 22m
$484
Showing 1-10 of 60 resultsSorted by cheapest first
Best time to book a flight from Missouri to Mexico
Have a flexible travel schedule? Discover the best time to fly to Mexico from Missouri with our price prediction graph.
STL-MEX
STL-SJD
STL-CUN
MCI-MEX
MCI-SJD
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Missouri to Mexico
USMO-MX0
STL-MEX
STL-SJD
STL-CUN
MCI-MEX
What is the cheapest month to book a flight from Missouri to Mexico?
Currently, January is the cheapest month in which you can book a flight from Missouri to Mexico (average of $556). Flying from Missouri to Mexico in December is currently the most expensive (average of $708). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from MO to MX?
Find hourly flight availability from Missouri to Mexico. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 23, 2026.
When flying from Missouri to Mexico, the time of day you decide to fly out makes little to no difference towards the overall price you’ll pay on tickets.
How far ahead should I book a flight from Missouri to Mexico?
The price you pay for your flight from Missouri to Mexico may vary depending on when you book. For the best chance of a lower fare, look to book 77 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mexico. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
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Alternative routes for Missouri to Mexico
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mexico by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Missouri to Mexico by cabin class
Find flights from Missouri to Mexico, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Missouri and Mexico flights
Browse other Missouri and Mexico flight options. Last updated on August 23, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Find a return flight route from Mexico
Find the right flight back to Missouri after your stay in Mexico
Missouri to Mexico flights
Consider these flights traveling from Missouri to Mexico.
Fly to Mexico regions
Consider these flights traveling to Mexico regions.
Top 10 airlines flying from Missouri to Mexico
Discover the top 10 airlines that operate flights from Missouri to Mexico. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated August 23, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$179 | Average$599 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$187 | Average$380 | FlexibilityNo cancel fee | On-time79% | |
| Cheapest$194 | Average$587 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$195 | Average$550 | FlexibilityNo cancel fee | On-time67% | |
| Cheapest$207 | Average$439 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$278 | Average$636 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$388 | Average$673 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$404 | Average$545 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$424 | Average$655 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$527 | Average$590 | FlexibilityNo cancel fee | On-time75% |