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Mesa

$74+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/8. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — PHX
Aug 15 — Aug 221
Sat 8/15
Sat 8/22
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 16, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:45 pm
MCI
-
PHX
1 stop9h 43m
Frontier
Mon 8/104:48 pm
PHX
-
MCI
1 stop18h 12m
Frontier
Deal found 7/11$139
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/302:17 pm
MCI
-
PHX
1 stop26h 18m
Frontier
Mon 10/53:40 pm
PHX
-
MCI
1 stop19h 42m
Frontier
Deal found 7/11$161
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/62:17 pm
MCI
-
PHX
1 stop19h 41m
Frontier
Tue 10/136:36 pm
PHX
-
MCI
1 stop16h 46m
Frontier
Deal found 7/11$166
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/171:45 pm
MCI
-
PHX
1 stop9h 43m
Frontier
Thu 8/204:48 pm
PHX
-
MCI
1 stop18h 05m
Frontier
Deal found 7/11$168
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/317:58 pm
STL
-
PHX
1 stop5h 41m
Frontier
Thu 9/38:35 am
PHX
-
STL
1 stop8h 38m
Frontier
Deal found 7/12$174
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:17 pm
MCI
-
PHX
1 stop29h 59m
Frontier
Mon 8/106:53 pm
PHX
-
MCI
1 stop16h 07m
Frontier
Deal found 7/11$177
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:08 pm
STL
-
PHX
1 stop13h 32m
Frontier
Wed 8/1211:23 pm
PHX
-
STL
1 stop16h 14m
Frontier
Deal found 7/11$190
This Kiwi.com deal was found by Cheapflights users on 7/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/232:17 pm
MCI
-
PHX
1 stop19h 41m
Frontier
Mon 9/285:55 pm
PHX
-
MCI
2 stops17h 27m
Frontier
Deal found 7/12$196
This Kiwi.com deal was found by Cheapflights users on 7/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:19 pm
STL
-
PHX
1 stop18h 54m
Frontier
Tue 10/205:55 pm
PHX
-
STL
2 stops23h 20m
Frontier
Deal found 7/15$196
This Kiwi.com deal was found by Cheapflights users on 7/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/81:45 pm
MCI
-
PHX
1 stop7h 02m
Frontier
Sat 8/156:53 pm
PHX
-
MCI
1 stop16h 07m
Frontier
Deal found 7/11$199
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:19 pm
STL
-
PHX
1 stop18h 54m
Frontier
Mon 10/198:16 am
PHX
-
STL
1 stop8h 59m
Frontier
Deal found 7/14$199
This Kiwi.com deal was found by Cheapflights users on 7/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:19 pm
STL
-
PHX
1 stop18h 54m
Frontier
Wed 10/218:16 am
PHX
-
STL
1 stop8h 59m
Frontier
Deal found 7/14$201

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated July 16, 2026.

Round-trip from

$139
(Kiwi.com)

One-way from

$74
(Kiwi.com)

Popular in

June

Cheapest in

November

Average price

$396
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($42 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 16, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Mon 8/17

7:15 pm-8:00 pm

Nonstop2h 45m

Phoenix Sky Harbor Intl

Thu 8/20

7:10 pm-11:45 pm

Nonstop2h 35m

$299

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 8/22

8:30 am-9:15 am

Nonstop2h 45m

Phoenix Sky Harbor Intl

Wed 8/26

6:15 am-12:45 pm

1 stop4h 30m

$305

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Tue 10/6

5:14 pm-8:51 pm

1 stop5h 37m

Phoenix Sky Harbor Intl

Mon 10/19

12:31 am-9:58 am

1 stop7h 27m

$308

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Thu 10/1

6:05 am-9:20 am

1 stop5h 15m

Phoenix Sky Harbor Intl

Mon 10/5

8:55 pm-1:25 am

Nonstop2h 30m

$309

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 8/12

2:20 pm-3:05 pm

Nonstop2h 45m

Phoenix Sky Harbor Intl

Sat 8/15

6:15 am-1:50 pm

1 stop5h 35m

$309

JoplinPhoenix

JLN - PHX

JLNPHX

Joplin

Sat 8/8

8:54 am-3:19 pm

1 stop8h 25m

Phoenix Sky Harbor Intl

Fri 8/14

4:49 pm-11:44 pm

1 stop4h 55m

$314

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Fri 9/25

11:20 am-3:43 pm

1 stop6h 23m

Phoenix Sky Harbor Intl

Tue 9/29

8:30 am-4:06 pm

1 stop5h 36m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Wed 8/5

5:50 am-9:00 am

1 stop5h 10m

Phoenix Sky Harbor Intl

Wed 8/19

6:01 am-4:11 pm

1 stop8h 10m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Thu 8/13

5:30 am-9:04 am

1 stop5h 34m

Phoenix Sky Harbor Intl

Thu 8/20

6:09 am-2:16 pm

1 stop6h 07m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Tue 10/20

5:30 am-9:07 am

1 stop5h 37m

Phoenix Sky Harbor Intl

Sat 10/24

6:00 am-2:16 pm

1 stop6h 16m

$319

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/11

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 16, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 18% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 16, 2026.

The most flights from USMO to MS9 are scheduled on a Tuesday (9 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Missouri to Mesa?

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on July 11, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 2h 45m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $47 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and United Airlines from $125 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider Envoy Air (100%), American Airlines (87%) or SkyWest Airlines (81%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $1,328 for a flight from Missouri to Mesa. The cheapest flight overall is $129 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $275.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 6 airlines flying from Missouri to Mesa

Discover the top 6 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 16, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$226FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$304FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$134Average$248FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$413FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$199Average$428FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$207Average$404FlexibilityNo cancel feeOn-time63%

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