Cheap flights from Missouri to Mesa, AZ
STL — PHX
Dec 12 — Dec 191
Round-trip
1 adult, Economy
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Everything you need to know about your flight from Missouri to Mesa
What is the cheapest time of day to fly from MO to MS9?
Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 12, 2026.
It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 34% on the flight price compared to flying in the afternoon, which is usually more expensive.
What is the cheapest day to fly from Missouri to Mesa?
Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on November 7, 2026.
Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Wednesday evenings flights should be avoided if possible as fares are typically the most expensive at this time.
Related info for your journey
Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for Missouri to Mesa
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Missouri and Mesa flights
Browse other Missouri and Mesa flight options. Last updated on November 12, 2026.
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Missouri to Mesa flights
Consider these flights traveling from Missouri to Mesa.
Top 6 airlines flying from Missouri to Mesa
Discover the top 6 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 12, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$97 | Average$239 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$134 | Average$297 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$148 | Average$382 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$220 | Average$377 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$237 | Average$437 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$269 | Average$441 | FlexibilityNo cancel fee | On-time63% |