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Mesa

$96+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/22. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Aug 24 — Aug 311
Mon 8/24
Mon 8/31
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.

This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 pm
STL
-
PHX
1 stop17h 32m
Frontier
Mon 9/149:06 am
PHX
-
STL
1 stop8h 09m
Frontier
Deal found 7/22$209
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:10 pm
STL
-
PHX
1 stop13h 48m
Frontier
Wed 10/73:21 pm
PHX
-
STL
1 stop25h 54m
Frontier
Deal found 7/23$210
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:08 pm
STL
-
PHX
1 stop16h 03m
Frontier
Wed 8/194:48 pm
PHX
-
STL
1 stop24h 25m
Frontier
Deal found 7/22$211
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
-
PHX
1 stop7h 19m
Frontier
Thu 8/206:35 am
PHX
-
STL
1 stop10h 38m
Frontier
Deal found 7/22$214
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
STL
-
PHX
1 stop13h 04m
Frontier
Wed 10/73:40 pm
PHX
-
STL
1 stop25h 35m
Frontier
Deal found 7/22$217
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
STL
-
PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
-
STL
1 stop11h 10m
Frontier
Deal found 7/22$218
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:35 am
STL
-
PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
-
STL
1 stop11h 10m
Frontier
Deal found 7/22$221
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:27 pm
STL
-
PHX
1 stop7h 33m
Frontier
Thu 8/278:35 am
PHX
-
STL
1 stop8h 38m
Frontier
Deal found 7/23$222
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:35 am
STL
-
PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
-
STL
1 stop11h 10m
Frontier
Deal found 7/22$224
This Kiwi.com deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:41 pm
STL
-
PHX
1 stop6h 34m
Frontier
Tue 10/208:16 am
PHX
-
STL
1 stop8h 59m
Frontier
Deal found 7/24$226
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1211:30 am
MCI
-
PHX
Nonstop2h 45m
Southwest
Thu 8/135:40 am
PHX
-
MCI
Nonstop2h 30m
Southwest
Deal found 7/21$257
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/271:38 pm
MCI
-
PHX
1 stop9h 50m
Frontier
Mon 8/319:03 am
PHX
-
MCI
1 stop4h 59m
Frontier
Deal found 7/20$258

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated July 25, 2026.

Round-trip from

$209
(Kiwi.com)

One-way from

$96
(Trip.com)

Popular in

June

Cheapest in

November

Average price

$393
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Sat 10/3

6:02 am-6:42 pm

2 stops14h 40m

Phoenix Sky Harbor Intl

Wed 10/7

7:38 am-11:59 pm

2 stops14h 21m

$264

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 10/24

6:05 am-7:05 am

Nonstop3h 00m

Phoenix Sky Harbor Intl

Tue 10/27

6:00 am-12:30 pm

1 stop4h 30m

$273

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Thu 10/1

2:15 pm-5:15 pm

1 stop5h 00m

Phoenix Sky Harbor Intl

Mon 10/5

5:05 am-9:35 am

Nonstop2h 30m

$277

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 11/17

7:40 am-9:35 am

Nonstop2h 55m

Phoenix Sky Harbor Intl

Thu 11/19

6:20 pm-9:45 pm

Nonstop2h 25m

$299

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 9/19

11:17 am-6:33 pm

1 stop9h 16m

Phoenix Sky Harbor Intl

Sat 9/26

8:49 am-8:33 pm

2 stops9h 44m

$324

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Wed 11/25

3:30 pm-12:06 am

1 stop9h 36m

Phoenix Sky Harbor Intl

Thu 12/3

7:05 am-2:50 pm

1 stop6h 45m

$329

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Fri 8/28

11:20 am-5:10 pm

1 stop7h 50m

Phoenix Sky Harbor Intl

Sun 8/30

4:49 pm-11:42 pm

1 stop4h 53m

$329

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Wed 11/25

3:30 pm-12:06 am

1 stop9h 36m

Phoenix Sky Harbor Intl

Fri 12/4

2:15 pm-10:32 pm

1 stop7h 17m

$329

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 8/22

5:30 am-8:41 am

1 stop5h 11m

Phoenix Sky Harbor Intl

Sat 8/29

2:19 pm-11:19 pm

1 stop7h 00m

$329

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 11/4

6:05 am-8:00 am

Nonstop2h 55m

Phoenix Sky Harbor Intl

Sun 11/8

6:20 am-9:45 am

Nonstop2h 25m

$343

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/24

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 25, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 19% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 25, 2026.

The most flights from USMO to MS9 are scheduled on a Thursday (9 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Missouri to Mesa?

Airfare is below average for this route at the moment.
Missouri to Mesa flights typically cost between $338 and $422 in September.
The cheapest round-trip price found within the last 5 days was $209 on Frontier (Sep 11-Sep 14).

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on July 18, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday mornings when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 3h. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $47 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and United Airlines from $125 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider SkyWest Airlines (90%), Alaska Airlines (84%) or American Airlines (83%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $360 for a flight from Missouri to Mesa. The cheapest flight overall is $148 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $259.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$226FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$304FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$134Average$254FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$413FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$199Average$433FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$212Average$406FlexibilityNo cancel feeOn-time63%
JetBlueCheapest$292Average$380FlexibilityNo cancel feeOn-time62%

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