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Mesa

$74+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Apr 26 — May 31
Sun 4/26
Sun 5/3
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.

This CheapOair deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:34 pm
MCI
-
PHX
1 stop10h 57m
Frontier
Mon 5/118:40 am
PHX
-
MCI
1 stop27h 09m
Frontier
Deal found 3/24$191
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/182:51 pm
MCI
-
PHX
1 stop7h 19m
Frontier
Wed 4/221:29 pm
PHX
-
MCI
2 stops19h 29m
Frontier
Deal found 3/26$196
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/2311:53 am
MCI
-
PHX
1 stop11h 31m
Frontier
Mon 4/276:50 am
PHX
-
MCI
1 stop4h 40m
Frontier
Deal found 3/25$197
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/232:15 pm
MCI
-
PHX
1 stop5h 32m
Frontier
Thu 4/306:50 am
PHX
-
MCI
1 stop4h 40m
Frontier
Deal found 3/26$198
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/111:19 am
MCI
-
PHX
1 stop12h 05m
Frontier
Mon 5/46:50 am
PHX
-
MCI
1 stop4h 40m
Frontier
Deal found 3/26$200
This Expedia deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/172:15 pm
MCI
-
PHX
1 stop23h 30m
Frontier
Sun 4/1910:29 pm
PHX
-
MCI
1 stop9h 59m
Frontier
Deal found 3/24$201
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:15 pm
MCI
-
PHX
1 stop19h 21m
Frontier
Fri 4/179:24 pm
PHX
-
MCI
1 stop14h 42m
Frontier
Deal found 3/26$202
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:34 pm
MCI
-
PHX
2 stops27h 02m
Frontier
Mon 5/116:53 pm
PHX
-
MCI
1 stop16h 56m
Frontier
Deal found 3/25$205
This Kiwi.com deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/62:34 pm
MCI
-
PHX
1 stop10h 57m
Frontier
Mon 5/1111:30 pm
PHX
-
MCI
2 stops36h 19m
Frontier
Deal found 3/23$206
This Kiwi.com deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:19 am
MCI
-
PHX
1 stop12h 05m
Frontier
Mon 4/206:50 am
PHX
-
MCI
1 stop4h 40m
Frontier
Deal found 3/25$208
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/162:15 pm
MCI
-
PHX
1 stop19h 21m
Frontier
Wed 4/221:29 pm
PHX
-
MCI
2 stops19h 29m
Frontier
Deal found 3/26$209
This Frontier deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/95:52 pm
MCI
-
PHX
Nonstop3h 13m
Frontier
Thu 4/1610:29 pm
PHX
-
MCI
1 stop10h 05m
Frontier
Deal found 3/26$210

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated March 27, 2026.

Round-trip from

$191
(CheapOair)

One-way from

$74
(Kiwi.com)

Popular in

March

Cheapest in

November

Average price

$390
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 6% potential increase in price ($26 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($4 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 5/6

7:25 am-10:35 am

1 stop5h 10m

Phoenix Sky Harbor Intl

Tue 5/12

5:55 pm-10:25 pm

Nonstop2h 30m

$231

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 4/29

7:25 am-10:35 am

1 stop5h 10m

Phoenix Sky Harbor Intl

Sat 5/2

4:55 pm-9:20 pm

Nonstop2h 25m

$278

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 4/20

6:05 am-7:30 am

Nonstop3h 25m

Phoenix Sky Harbor Intl

Tue 4/21

5:35 am-10:25 am

Nonstop2h 50m

$278

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Sat 4/11

4:59 pm-7:35 am

2 stops16h 36m

Phoenix Sky Harbor Intl

Thu 4/16

8:52 am-7:21 pm

1 stop8h 29m

$279

Cape GirardeauPhoenix

CGI - PHX

CGIPHX

Cape Girardeau

Sun 4/19

9:45 am-9:57 am

1 stop26h 12m

Phoenix Sky Harbor Intl

Thu 4/23

11:19 am-1:50 pm

1 stop24h 31m

$324

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Thu 4/23

5:55 am-9:35 am

1 stop5h 40m

Phoenix Sky Harbor Intl

Mon 4/27

8:25 pm-12:50 am

Nonstop2h 25m

$329

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Sun 5/3

5:35 am-7:00 am

Nonstop3h 25m

Phoenix Sky Harbor Intl

Tue 5/5

11:10 am-5:55 pm

1 stop4h 45m

$332

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 5/20

8:45 pm-10:10 pm

Nonstop3h 25m

Phoenix Sky Harbor Intl

Thu 5/21

4:40 pm-11:50 pm

1 stop5h 10m

$336

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 5/6

3:55 pm-7:55 pm

1 stop6h 00m

Phoenix Sky Harbor Intl

Sun 5/10

7:55 am-12:55 pm

Nonstop3h 00m

$336

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Fri 5/1

4:50 pm-9:05 pm

1 stop6h 15m

Phoenix Sky Harbor Intl

Sun 5/10

4:35 pm-12:47 am

1 stop6h 12m

$339

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/23

Showing 1-10 of 60 resultsSorted by cheapest first
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6

Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, February is the cheapest month in which you can book a flight from Missouri to Mesa (average of $97). Flying from Missouri to Mesa in May is currently the most expensive (average of $162). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated March 27, 2026.

It’s typically best to fly out from Missouri to Mesa in the afternoon. Doing so could potentially save you 14% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on March 23, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated March 27, 2026.

The most flights from USMO to MS9 are scheduled on a Thursday (12 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Missouri to Mesa?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 5h 10m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $47 on Frontier. Other airlines that offer cheap prices include Southwest from $105 and American Airlines from $107 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Kansas City - Phoenix Sky Harbor Intl. You may also consider Lambert-St Louis - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider American Airlines (86%), Alaska Airlines (86%) or Southwest (82%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $342 for a flight from Missouri to Mesa. The cheapest flight overall is $128 while the most popular route, (Kansas City - Phoenix Sky Harbor Intl) is currently priced at $208.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, February is the cheapest month in which you can book a flight from Missouri to Mesa (average of $97). Flying from Missouri to Mesa in May is currently the most expensive (average of $162). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Mesa

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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$218FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$300FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$121Average$200FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$137Average$208FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$375FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$195Average$434FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$198Average$384FlexibilityNo cancel feeOn-time63%

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