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Mesa

$28+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Dec 6 — Dec 131
Sat 12/6
Sat 12/13
1 adult, Economy
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Find flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 6, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Sun 12/2810:31 pmPHX - MCI
1 stop20h 19mFrontier
Deal found 11/6$134
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/1612:31 pmMCI - PHX
Nonstop2h 54mFrontier
Wed 11/199:59 amPHX - MCI
1 stop6h 20mFrontier
Deal found 11/4$135
This Mytrip deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/196:49 pmMCI - PHX
1 stop15h 06mFrontier
Fri 11/2110:11 pmPHX - MCI
1 stop20h 22mFrontier
Deal found 11/5$136
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Thu 1/110:31 pmPHX - MCI
1 stop20h 19mFrontier
Deal found 11/4$137
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:48 pmMCI - PHX
1 stop25h 19mFrontier
Sun 12/710:26 pmPHX - MCI
1 stop20h 24mFrontier
Deal found 11/4$138
This American Airlines deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/107:10 amMCI - PHX
Nonstop3h 02mAmerican Airlines
Wed 12/178:06 pmPHX - MCI
Nonstop2h 33mAmerican Airlines
Deal found 11/5$139
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Fri 1/29:31 amPHX - MCI
1 stop9h 19mFrontier
Deal found 11/5$140
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/118:09 pmMCI - PHX
1 stop12h 57mFrontier
Sun 12/149:16 amPHX - MCI
1 stop9h 34mFrontier
Deal found 11/5$141
This CheapOair deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:28 pmMCI - PHX
1 stop5h 04mFrontier
Sat 12/64:12 pmPHX - MCI
1 stop26h 38mFrontier
Deal found 11/4$142
This Kiwi.com deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:45 pmMCI - PHX
2 stops18h 49mFrontier
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 11/4$143
This Frontier deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/218:28 pmMCI - PHX
1 stop5h 04mFrontier
Sun 11/237:00 amPHX - MCI
1 stop11h 33mFrontier
Deal found 11/4$144
This Priceline deal was found by Cheapflights users on 11/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/248:28 pmMCI - PHX
1 stop5h 04mFrontier
Thu 12/49:16 amPHX - MCI
1 stop8h 58mFrontier
Deal found 11/4$145

Cheap flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated November 6, 2025.

Round-trip from

$134
(Kiwi.com)

One-way from

$28
(Kiwi.com)

Popular in

March

Cheapest in

November

Average price

$328
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($39 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Missouri

Fly to

Mesa

Route

Depart

Return

Price

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 1/12

8:45 am-11:36 pm

2 stops15h 51m

Phoenix Sky Harbor Intl

Tue 1/20

5:12 pm-10:02 am

1 stop15h 50m

$170

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 2/2

7:43 pm-4:04 pm

1 stop21h 21m

Phoenix Sky Harbor Intl

Sat 2/7

6:54 pm-9:47 am

2 stops13h 53m

$174

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 1/12

8:45 am-11:36 pm

2 stops15h 51m

Phoenix Sky Harbor Intl

Sun 1/18

10:31 pm-10:04 am

1 stop10h 33m

$188

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 12/5

9:20 am-11:15 am

Nonstop2h 55m

Phoenix Sky Harbor Intl

Mon 12/8

4:25 pm-7:55 pm

Nonstop2h 30m

$209

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 11/10

12:09 pm-2:31 pm

Nonstop3h 22m

Phoenix Sky Harbor Intl

Wed 11/12

9:05 pm-9:07 am

1 stop11h 02m

$209

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 12/13

12:05 pm-2:00 pm

Nonstop2h 55m

Phoenix Sky Harbor Intl

Fri 1/30

3:35 pm-10:20 pm

1 stop5h 45m

$218

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 12/10

9:20 am-11:15 am

Nonstop2h 55m

Phoenix Sky Harbor Intl

Wed 12/17

6:15 am-11:55 am

1 stop4h 40m

$225

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Fri 12/5

5:34 pm-12:04 am

1 stop7h 30m

Phoenix Sky Harbor Intl

Thu 12/11

12:59 am-9:10 am

1 stop7h 11m

$229

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 12/2

7:45 am-12:40 pm

1 stop5h 55m

Phoenix Sky Harbor Intl

Sat 12/6

8:55 am-12:25 pm

Nonstop2h 30m

$229

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Fri 12/5

5:34 pm-12:04 am

1 stop7h 30m

Phoenix Sky Harbor Intl

Mon 12/8

6:30 pm-12:48 am

1 stop5h 18m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/4

Showing 1-10 of 59 results
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, October is the cheapest month in which you can book a flight from Missouri to Mesa (average of $122). Flying from Missouri to Mesa in March is currently the most expensive (average of $187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 6, 2025.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 44% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 6, 2025.

The most flights from USMO to MS9 are scheduled on a Thursday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 2h 55m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $70 on Southwest. Other airlines that offer cheap prices include Frontier from $79 and Delta from $99 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider SkyWest Airlines (100%), Alaska Airlines (83%) or American Airlines (82%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $409 for a flight from Missouri to Mesa. The cheapest flight overall is $69 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $99.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, October is the cheapest month in which you can book a flight from Missouri to Mesa (average of $122). Flying from Missouri to Mesa in March is currently the most expensive (average of $187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Mesa

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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 6, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$94Average$205FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$232FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$140Average$236FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$216Average$397FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$223Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$224Average$428FlexibilityNo cancel feeOn-time71%
DeltaCheapest$234Average$342FlexibilityNo cancel feeOn-timeN/A

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