HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Mesa

$77+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/27. Fares are subject to change and may not be available on all flights or dates of travel.
MCI — PHX
Jul 20 — Jul 271
Mon 7/20
Mon 7/27
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Missouri to Mesa with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 20, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:32 pm
MCI
-
PHX
1 stop22h 27m
Frontier
Wed 8/59:58 pm
PHX
-
MCI
1 stop15h 49m
Frontier
Deal found 6/17$163
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:45 pm
MCI
-
PHX
1 stop11h 47m
Frontier
Wed 7/299:58 pm
PHX
-
MCI
1 stop15h 49m
Frontier
Deal found 6/17$188
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/211:45 pm
MCI
-
PHX
1 stop11h 47m
Frontier
Wed 8/52:04 pm
PHX
-
MCI
1 stop23h 43m
Frontier
Deal found 6/17$190
This Kiwi.com deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:32 pm
MCI
-
PHX
1 stop22h 27m
Frontier
Thu 8/67:45 am
PHX
-
MCI
1 stop6h 02m
Frontier
Deal found 6/17$196
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:32 pm
MCI
-
PHX
1 stop22h 27m
Frontier
Fri 8/77:45 am
PHX
-
MCI
1 stop6h 02m
Frontier
Deal found 6/16$200
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/174:32 pm
MCI
-
PHX
1 stop20h 52m
Frontier
Thu 8/2010:27 pm
PHX
-
MCI
1 stop12h 28m
Frontier
Deal found 6/16$204
This Frontier deal was found by Cheapflights users on 6/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/172:17 pm
MCI
-
PHX
1 stop5h 18m
Frontier
Wed 11/187:40 am
PHX
-
MCI
1 stop4h 42m
Frontier
Deal found 6/17$210
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/204:32 pm
MCI
-
PHX
1 stop22h 27m
Frontier
Tue 8/46:53 pm
PHX
-
MCI
1 stop16h 07m
Frontier
Deal found 6/16$211
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:10 pm
STL
-
PHX
2 stops22h 21m
Frontier
Thu 8/137:45 am
PHX
-
STL
1 stop8h 30m
Frontier
Deal found 6/16$239
This Frontier deal was found by Cheapflights users on 6/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:45 pm
STL
-
PHX
1 stop6h 39m
Frontier
Tue 9/2210:55 pm
PHX
-
STL
1 stop10h 56m
Frontier
Deal found 6/19$240
This Kiwi.com deal was found by Cheapflights users on 6/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:10 pm
STL
-
PHX
1 stop19h 49m
Frontier
Thu 7/307:45 am
PHX
-
STL
1 stop8h 30m
Frontier
Deal found 6/16$241
This Kiwi.com deal was found by Cheapflights users on 6/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/118:08 pm
STL
-
PHX
1 stop5h 24m
Frontier
Tue 7/219:58 pm
PHX
-
STL
1 stop18h 07m
Frontier
Deal found 6/18$242

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated June 20, 2026.

Round-trip from

$163
(Kiwi.com)

One-way from

$77
(Kiwi.com)

Popular in

June

Cheapest in

October

Average price

$415
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($41 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in June 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 9/12

11:17 am-5:52 pm

1 stop8h 35m

Phoenix Sky Harbor Intl

Sun 9/27

11:52 pm-10:37 am

1 stop8h 45m

$308

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Wed 9/23

6:15 am-11:08 am

1 stop6h 53m

Phoenix Sky Harbor Intl

Sun 9/27

11:52 pm-10:37 am

1 stop8h 45m

$308

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Wed 11/25

11:40 am-6:36 pm

1 stop7h 56m

Phoenix Sky Harbor Intl

Thu 12/3

7:05 am-2:50 pm

1 stop6h 45m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Fri 12/11

11:40 am-6:36 pm

1 stop7h 56m

Phoenix Sky Harbor Intl

Tue 12/15

2:15 pm-10:32 pm

1 stop7h 17m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Thu 7/23

5:50 am-9:00 am

1 stop5h 10m

Phoenix Sky Harbor Intl

Tue 7/28

6:10 am-4:20 pm

1 stop8h 10m

$319

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Thu 11/5

3:30 pm-12:06 am

1 stop9h 36m

Phoenix Sky Harbor Intl

Wed 11/11

11:00 am-6:10 pm

1 stop6h 10m

$319

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Thu 7/23

1:45 pm-10:59 pm

2 stops11h 14m

Phoenix Sky Harbor Intl

Mon 7/27

6:53 pm-1:00 pm

1 stop16h 07m

$353

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 11/4

8:25 am-12:25 pm

1 stop5h 00m

Phoenix Sky Harbor Intl

Mon 11/9

3:10 pm-7:00 pm

Nonstop2h 50m

$368

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Tue 9/22

7:35 am-8:50 am

Nonstop3h 15m

Phoenix Sky Harbor Intl

Tue 9/29

6:00 am-10:55 am

Nonstop2h 55m

$373

JoplinPhoenix

JLN - PHX

JLNPHX

Joplin

Thu 7/9

8:54 am-3:19 pm

1 stop8h 25m

Phoenix Sky Harbor Intl

Mon 7/13

11:12 am-11:44 pm

2 stops10h 32m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/19

Showing 1-10 of 60 resultsSorted by cheapest first
1
2
3
...
6

Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 20, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 23% on the flight price compared to flying in the afternoon, which is usually more expensive.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated June 20, 2026.

The most flights from USMO to MS9 are scheduled on a Tuesday (9 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

How much does it cost to fly round-trip from Missouri to Mesa?

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on June 13, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 6h 53m. Airlines will cover a distance of 1161 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $47 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and United Airlines from $125 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Kansas City - Phoenix Sky Harbor Intl. You may also consider Lambert-St Louis - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider Envoy Air (100%), American Airlines (84%) or SkyWest Airlines (78%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $359 for a flight from Missouri to Mesa. The cheapest flight overall is $174 while the most popular route, (Kansas City - Phoenix Sky Harbor Intl) is currently priced at $260.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
Dallas/Fort Worth to Las Vegas flights
Newark to Las Vegas flights
John F Kennedy Intl to Las Vegas flights
O'Hare Intl to Las Vegas flights
Hobby to Las Vegas flights
Atlanta to Las Vegas flights
Los Angeles to Las Vegas flights
Seattle to Las Vegas flights
San Francisco to Las Vegas flights
George Bush Intcntl to Las Vegas flights
Dulles Intl to Las Vegas flights
Detroit to Las Vegas flights
Santa Rosa to Las Vegas flights
LaGuardia to Las Vegas flights
Denver to Las Vegas flights
Boston to Las Vegas flights
Baltimore to Las Vegas flights
Reagan-National to Las Vegas flights
Orlando to Las Vegas flights
San Jose to Las Vegas flights
Seattle to Sky Harbor Intl flights
Cleveland to Las Vegas flights
O'Hare Intl to Sky Harbor Intl flights
Austin to Las Vegas flights
Midway to Las Vegas flights
Newark to Sky Harbor Intl flights
Santa Ana to Las Vegas flights
Fort Lauderdale to Las Vegas flights
Charlotte to Las Vegas flights
San Antonio to Las Vegas flights
Philadelphia to Las Vegas flights
Minneapolis to Las Vegas flights
John F Kennedy Intl to Sky Harbor Intl flights
Love Field to Las Vegas flights
Burbank to Las Vegas flights
Los Angeles to Sky Harbor Intl flights
Portland to Las Vegas flights
Tampa to Las Vegas flights
Sky Harbor Intl to Las Vegas flights
Cincinnati to Las Vegas flights
St. Louis to Las Vegas flights
Sacramento to Las Vegas flights
Detroit to Sky Harbor Intl flights
Dallas/Fort Worth to Sky Harbor Intl flights
Honolulu to Las Vegas flights
Oakland to Las Vegas flights
Dulles Intl to Sky Harbor Intl flights
Minneapolis to Sky Harbor Intl flights
Pittsburgh to Las Vegas flights
Raleigh to Las Vegas flights

Top 6 airlines flying from Missouri to Mesa

Discover the top 6 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 20, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$218FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$320FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$144Average$228FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$415FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$196Average$448FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$204Average$399FlexibilityNo cancel feeOn-time63%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.