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Mesa

$83+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/3. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Jun 10 — Jun 171
Wed 6/10
Wed 6/17
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 11, 2026.

This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/28:08 pm
STL
-
PHX
2 stops23h 35m
Frontier
Tue 6/911:21 am
PHX
-
STL
1 stop6h 02m
Frontier
Deal found 5/11$223
This Frontier deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/26:51 pm
STL
-
PHX
1 stop6h 33m
Frontier
Mon 6/87:40 am
PHX
-
STL
1 stop10h 31m
Frontier
Deal found 5/11$224
This Super.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/66:30 pm
STL
-
PHX
1 stop6h 54m
Frontier
Sun 6/214:43 pm
PHX
-
STL
1 stop24h 10m
Frontier
Deal found 5/9$229
This Frontier deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/107:03 pm
STL
-
PHX
1 stop5h 57m
Frontier
Sun 6/146:24 am
PHX
-
STL
1 stop9h 54m
Frontier
Deal found 5/9$230
This Super.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
-
PHX
1 stop5h 21m
Frontier
Sat 5/307:40 am
PHX
-
STL
1 stop7h 54m
Frontier
Deal found 5/10$232
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/237:03 pm
STL
-
PHX
1 stop6h 01m
Frontier
Fri 6/2610:32 pm
PHX
-
STL
1 stop13h 34m
Frontier
Deal found 5/8$233
This Kiwi.com deal was found by Cheapflights users on 5/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
-
PHX
1 stop5h 21m
Frontier
Mon 6/111:26 am
PHX
-
STL
2 stops29h 57m
Frontier
Deal found 5/6$235
This Trip.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/266:51 pm
STL
-
PHX
1 stop6h 33m
Frontier
Fri 5/2911:30 pm
PHX
-
STL
1 stop7h 25m
Frontier
Deal found 5/8$236
This Super.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/59:06 pm
STL
-
PHX
1 stop28h 18m
Frontier
Sat 6/206:24 am
PHX
-
STL
1 stop10h 10m
Frontier
Deal found 5/9$237
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/114:52 pm
STL
-
PHX
1 stop7h 26m
Frontier
Sat 7/186:40 am
PHX
-
STL
1 stop10h 43m
Frontier
Deal found 5/10$238
This Kiwi.com deal was found by Cheapflights users on 5/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:51 pm
STL
-
PHX
1 stop6h 33m
Frontier
Mon 6/810:27 pm
PHX
-
STL
2 stops17h 03m
Frontier
Deal found 5/8$239
This Frontier deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/288:08 pm
STL
-
PHX
1 stop5h 21m
Frontier
Tue 6/26:00 am
PHX
-
STL
1 stop6h 48m
Frontier
Deal found 5/10$240

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated May 11, 2026.

Round-trip from

$224
(Frontier)

One-way from

$83
(Kiwi.com)

Popular in

April

Cheapest in

October

Average price

$375
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 8% potential increase in price ($34 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 5/23

7:39 pm-12:21 am

1 stop6h 42m

Phoenix Sky Harbor Intl

Sat 5/30

12:35 am-8:59 am

1 stop6h 24m

$301

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Thu 6/11

7:53 pm-12:20 am

1 stop6h 27m

Phoenix Sky Harbor Intl

Tue 6/16

1:15 am-10:04 am

1 stop6h 49m

$330

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 6/18

6:47 pm-12:20 am

1 stop7h 33m

Phoenix Sky Harbor Intl

Sat 6/20

12:50 am-10:06 am

1 stop7h 16m

$338

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 7/1

7:55 pm-11:20 pm

1 stop5h 25m

Phoenix Sky Harbor Intl

Wed 7/8

6:35 pm-11:10 pm

Nonstop2h 35m

$355

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Tue 8/18

3:12 pm-10:52 pm

1 stop9h 40m

Phoenix Sky Harbor Intl

Sat 8/22

9:23 am-10:35 pm

2 stops11h 12m

$376

Cape GirardeauPhoenix

CGI - PHX

CGIPHX

Cape Girardeau

Tue 6/9

3:30 pm-11:04 pm

1 stop9h 34m

Phoenix Sky Harbor Intl

Tue 6/16

9:30 am-5:35 pm

2 stops30h 05m

$379

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 7/8

8:00 pm-8:45 pm

Nonstop2h 45m

Phoenix Sky Harbor Intl

Sun 7/12

8:10 pm-12:45 am

Nonstop2h 35m

$379

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 6/3

5:30 am-6:55 am

Nonstop3h 25m

Phoenix Sky Harbor Intl

Wed 6/10

10:50 am-5:45 pm

1 stop4h 55m

$391

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 5/19

4:15 pm-9:05 pm

1 stop6h 50m

Phoenix Sky Harbor Intl

Wed 5/20

6:00 am-12:43 pm

1 stop4h 43m

$405

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 6/1

6:00 pm-7:25 pm

Nonstop3h 25m

Phoenix Sky Harbor Intl

Wed 6/3

4:20 pm-9:10 pm

Nonstop2h 50m

$406

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/6

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 11, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on May 9, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated May 11, 2026.

The most flights from USMO to MS9 are scheduled on a Friday (14 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (4 on average).

How much does it cost to fly round-trip from Missouri to Mesa?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 5h 25m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $48 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and Southwest from $107 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider Envoy Air (100%), Alaska Airlines (87%) or American Airlines (83%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $391 for a flight from Missouri to Mesa. The cheapest flight overall is $193 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $304.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 11, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$219FlexibilityNo cancel feeOn-time62%
DeltaCheapest$98Average$320FlexibilityNo cancel feeOn-timeN/A
Spirit AirlinesCheapest$121Average$199FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$134Average$215FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$397FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$195Average$437FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$197Average$391FlexibilityNo cancel feeOn-time63%

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