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Mesa

$28+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/18. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
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Find flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This CheapOair deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/18:28 pmMCI - PHX
1 stop19h 39mFrontier
Sun 12/77:25 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 11/11$129
This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/410:52 amMCI - PHX
Nonstop3h 02mFrontier
Mon 12/159:16 amPHX - MCI
1 stop9h 34mFrontier
Deal found 11/11$130
This CheapOair deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:32 pmMCI - PHX
Nonstop3h 02mFrontier
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 11/13$131
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/187:00 amMCI - PHX
1 stop13h 16mMultiple Airlines
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mMultiple Airlines
Deal found 11/11$132
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/166:30 amMCI - PHX
1 stop13h 01mMultiple Airlines
Fri 12/1910:31 pmPHX - MCI
1 stop20h 20mMultiple Airlines
Deal found 11/11$133
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/148:45 pmMCI - PHX
1 stop15h 20mFrontier
Sun 12/217:00 amPHX - MCI
1 stop11h 51mFrontier
Deal found 11/12$137
This CheapOair deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/52:48 pmMCI - PHX
1 stop10h 56mFrontier
Sun 12/77:00 amPHX - MCI
1 stop11h 50mFrontier
Deal found 11/12$138
This CheapOair deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/218:45 pmMCI - PHX
1 stop4h 44mFrontier
Fri 12/267:00 amPHX - MCI
1 stop11h 50mFrontier
Deal found 11/12$144
This CheapOair deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/197:43 pmSTL - PHX
1 stop19h 50mFrontier
Sat 12/277:00 amPHX - STL
1 stop13h 25mFrontier
Deal found 11/13$144
This Frontier deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmMCI - PHX
1 stop4h 44mFrontier
Fri 1/99:05 amPHX - MCI
1 stop9h 46mFrontier
Deal found 11/11$145
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:43 pmSTL - PHX
1 stop14h 12mFrontier
Sun 11/2310:43 pmPHX - STL
1 stop21h 26mFrontier
Deal found 11/12$145
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/208:45 pmMCI - PHX
1 stop12h 36mFrontier
Mon 12/2210:31 pmPHX - MCI
1 stop20h 19mFrontier
Deal found 11/10$146

Cheap flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated November 13, 2025.

Round-trip from

$129
(CheapOair)

One-way from

$28
(Kiwi.com)

Popular in

March

Cheapest in

October

Average price

$321
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 10% potential increase in price ($43 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($9 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Missouri

Fly to

Mesa

Route

Depart

Return

Price

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Mon 11/24

6:16 pm-12:36 am

1 stop7h 20m

Phoenix Sky Harbor Intl

Tue 12/2

7:00 am-1:27 pm

1 stop5h 27m

$197

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Mon 11/24

6:16 pm-12:36 am

1 stop7h 20m

Phoenix Sky Harbor Intl

Wed 12/3

3:20 pm-11:10 pm

1 stop6h 50m

$197

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 2/21

5:50 pm-7:50 pm

Nonstop3h 00m

Phoenix Sky Harbor Intl

Sat 2/28

8:55 am-1:35 pm

1 stop3h 40m

$214

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 2/4

3:25 pm-8:15 pm

1 stop5h 50m

Phoenix Sky Harbor Intl

Sat 2/21

6:05 am-9:30 am

Nonstop2h 25m

$218

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 2/11

12:10 pm-5:40 pm

2 stops6h 30m

Phoenix Sky Harbor Intl

Sun 2/15

8:50 am-3:15 pm

1 stop5h 25m

$233

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 12/5

7:15 am-11:15 am

1 stop5h 00m

Phoenix Sky Harbor Intl

Wed 12/10

8:55 am-12:25 pm

Nonstop2h 30m

$239

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 2/21

9:00 am-1:39 pm

1 stop5h 39m

Phoenix Sky Harbor Intl

Sat 2/28

12:58 pm-8:40 pm

1 stop6h 42m

$248

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Tue 12/9

8:00 am-3:48 pm

1 stop8h 48m

Phoenix Sky Harbor Intl

Tue 12/16

1:45 pm-9:22 pm

1 stop6h 37m

$248

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 2/21

1:25 pm-6:14 pm

1 stop5h 49m

Phoenix Sky Harbor Intl

Sat 2/28

7:10 am-1:57 pm

1 stop5h 47m

$251

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sun 12/21

7:25 pm-12:34 am

1 stop6h 09m

Phoenix Sky Harbor Intl

Sat 12/27

6:25 pm-11:56 pm

1 stop4h 31m

$259

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/12

Showing 1-10 of 56 results
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $101). Flying from Missouri to Mesa in March is currently the most expensive (average of $187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 44% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Friday evenings when fares are most often at their lowest. Saturday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated November 13, 2025.

The most flights from USMO to MS9 are scheduled on a Thursday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 3h. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $54 on Frontier. Other airlines that offer cheap prices include Southwest from $70 and United Airlines from $109 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider SkyWest Airlines (100%), Alaska Airlines (83%) or American Airlines (82%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $409 for a flight from Missouri to Mesa. The cheapest flight overall is $69 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $130.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $101). Flying from Missouri to Mesa in March is currently the most expensive (average of $187). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Mesa

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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$94Average$205FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$232FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$140Average$236FlexibilityNo cancel feeOn-time88%
SouthwestCheapest$216Average$397FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$223Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$224Average$428FlexibilityNo cancel feeOn-time71%
DeltaCheapest$234Average$342FlexibilityNo cancel feeOn-timeN/A

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