Mesa

$79+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/26. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
May 30 — Jun 61
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 30, 2026.

This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/152:34 pm
MCI
-
PHX
1 stop8h 36m
Frontier
Mon 5/187:40 pm
PHX
-
MCI
2 stops16h 09m
Frontier
Deal found 4/25$234
This Orbitz deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/126:51 pm
STL
-
PHX
1 stop6h 33m
Frontier
Sat 5/2310:27 pm
PHX
-
STL
1 stop19h 44m
Frontier
Deal found 4/29$236
This United Airlines deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/115:40 am
SGF
-
PHX
1 stop6h 53m
United Airlines
Tue 8/186:10 am
PHX
-
SGF
1 stop6h 06m
United Airlines
Deal found 4/25$237
This Booking.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/177:03 pm
STL
-
PHX
1 stop6h 01m
Frontier
Sun 6/217:45 am
PHX
-
STL
1 stop28h 21m
Frontier
Deal found 4/29$237
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/23:33 pm
STL
-
PHX
1 stop22h 37m
Frontier
Sat 6/64:17 pm
PHX
-
STL
2 stops20h 14m
Frontier
Deal found 4/29$239
This Travelocity deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Travelocity is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/82:34 pm
MCI
-
PHX
1 stop27h 21m
Frontier
Mon 5/114:17 pm
PHX
-
MCI
1 stop19h 32m
Frontier
Deal found 4/27$242
This Kiwi.com deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/142:34 pm
MCI
-
PHX
2 stops33h 40m
Frontier
Thu 5/285:15 am
PHX
-
MCI
1 stop6h 34m
Frontier
Deal found 4/25$243
This Frontier deal was found by Cheapflights users on 4/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:06 pm
STL
-
PHX
1 stop7h 14m
Frontier
Thu 7/96:40 am
PHX
-
STL
1 stop10h 43m
Frontier
Deal found 4/30$244
This Frontier deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/302:34 pm
MCI
-
PHX
1 stop8h 36m
Frontier
Mon 6/85:15 am
PHX
-
MCI
1 stop6h 34m
Frontier
Deal found 4/27$245
This Expedia deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:34 pm
MCI
-
PHX
1 stop10h 55m
Frontier
Sat 5/238:40 am
PHX
-
MCI
1 stop27h 09m
Frontier
Deal found 4/26$246
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/22:34 pm
MCI
-
PHX
1 stop10h 55m
Frontier
Mon 6/810:27 pm
PHX
-
MCI
2 stops12h 33m
Frontier
Deal found 4/27$247
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/1712:36 pm
STL
-
PHX
1 stop22h 11m
Frontier
Wed 5/2012:29 pm
PHX
-
STL
2 stops25h 46m
Frontier
Deal found 4/29$247

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated April 30, 2026.

Round-trip from

$234
(Kiwi.com)

One-way from

$79
(Super.com)

Popular in

April

Cheapest in

November

Average price

$392
From Missouri to Mesa
One-way flight from Missouri to Mesa
Highest demand for flights based on searches. 9% potential increase in price ($34 potential increase over avg. RT price).
Cheapest flight prices on average. 1% potential price decrease ($5 potential savings vs. average RT price).
Average for round-trip flights in April 2026

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Tue 8/11

5:40 am-10:33 am

1 stop6h 53m

Phoenix Sky Harbor Intl

Tue 8/18

6:10 am-2:16 pm

1 stop6h 06m

$237

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 8/15

3:30 pm-10:47 pm

1 stop9h 17m

Phoenix Sky Harbor Intl

Sat 8/22

6:05 am-2:45 pm

1 stop6h 40m

$303

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 5/26

4:25 pm-7:55 pm

1 stop5h 30m

Phoenix Sky Harbor Intl

Sat 5/30

6:00 am-10:25 am

Nonstop2h 25m

$325

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Mon 8/17

5:00 pm-8:45 pm

1 stop5h 45m

Phoenix Sky Harbor Intl

Mon 8/24

8:30 am-4:21 pm

1 stop5h 51m

$332

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 6/3

12:25 pm-1:20 pm

Nonstop2h 55m

Phoenix Sky Harbor Intl

Mon 6/8

8:55 pm-1:30 am

Nonstop2h 35m

$346

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Tue 5/26

7:39 pm-12:14 am

1 stop6h 35m

Phoenix Sky Harbor Intl

Wed 7/22

1:15 am-10:03 am

1 stop6h 48m

$349

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 5/15

5:21 pm-11:33 pm

1 stop8h 12m

Phoenix Sky Harbor Intl

Tue 5/19

6:00 am-3:58 pm

1 stop7h 58m

$358

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 6/6

5:53 pm-7:00 pm

Nonstop3h 07m

Phoenix Sky Harbor Intl

Sat 6/13

12:32 pm-5:16 pm

Nonstop2h 44m

$365

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 6/18

6:47 pm-12:20 am

1 stop7h 33m

Phoenix Sky Harbor Intl

Sat 6/20

12:50 am-10:06 am

1 stop7h 16m

$369

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 6/5

9:15 pm-10:00 pm

Nonstop2h 45m

Phoenix Sky Harbor Intl

Tue 6/9

3:30 pm-10:00 pm

1 stop4h 30m

$370

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/25

Showing 1-10 of 60 resultsSorted by cheapest first
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 30, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 13% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on April 25, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Missouri to Mesa?

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 5h 30m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $48 on Frontier. Other airlines that offer cheap prices include American Airlines from $104 and Southwest from $107 one-way.

  • What are the most popular routes from Missouri to Mesa?

  • What are the most reliable airlines from Missouri to Mesa?

    Consider Envoy Air (100%), American Airlines (90%) or Alaska Airlines (89%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $379 for a flight from Missouri to Mesa. The cheapest flight overall is $170 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $222.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 30, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$68Average$219FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$121Average$199FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$138Average$210FlexibilityNo cancel feeOn-time88%
DeltaCheapest$138Average$300FlexibilityNo cancel feeOn-timeN/A
United AirlinesCheapest$148Average$394FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$195Average$426FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$197Average$389FlexibilityNo cancel feeOn-time63%

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