Mesa

$56+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/23. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Oct 16 — Oct 231
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Cheap flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated September 16, 2025.

Round-trip from

$150
(Cheapflightsfares)

One-way from

$56
(Cheapflightsfares)

Popular in

March

Cheapest in

August

Average price

$359
From Missouri to Mesa
One-way flight from Missouri to Mesa
Highest demand for flights based on searches. 9% potential increase in price ($40 potential increase over avg. RT price).
Cheapest flight prices on average. 2% potential price decrease ($8 potential savings vs. average RT price).
Average for round-trip flights in September 2025

Find flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 16, 2025.

This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:45 pmSTL - PHX
1 stop5h 44mFrontier
Mon 11/107:25 amPHX - STL
Nonstop2h 59mFrontier
Deal found 9/15$150
This Cheapflightsfares deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1010:59 pmSTL - PHX
Nonstop3h 22mFrontier
Mon 10/132:27 pmPHX - STL
Nonstop2h 59mFrontier
Deal found 9/15$151
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/210:49 amSTL - PHX
1 stop10h 21mFrontier
Sun 10/56:00 amPHX - STL
1 stop7h 04mFrontier
Deal found 9/15$152
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/127:52 pmSTL - PHX
1 stop14h 07mFrontier
Mon 10/139:59 pmPHX - STL
1 stop9h 08mFrontier
Deal found 9/15$153
This Booking.com deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/274:58 pmSTL - PHX
1 stop7h 51mFrontier
Sun 9/286:00 amPHX - STL
1 stop25h 06mFrontier
Deal found 9/16$154
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1710:59 pmSTL - PHX
Nonstop3h 22mFrontier
Sun 10/198:03 pmPHX - STL
1 stop13h 40mFrontier
Deal found 9/15$155
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/157:52 pmSTL - PHX
1 stop14h 07mFrontier
Fri 10/179:59 pmPHX - STL
1 stop9h 08mFrontier
Deal found 9/15$158
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/263:01 pmMCI - PHX
1 stop6h 24mFrontier
Mon 9/297:00 amPHX - MCI
1 stop4h 48mFrontier
Deal found 9/15$160
This Frontier deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/264:00 pmMCI - PHX
Nonstop2h 54mFrontier
Fri 11/712:55 pmPHX - MCI
1 stop5h 38mFrontier
Deal found 9/15$161
This Booking.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:38 pmMCI - PHX
1 stop27h 17mFrontier
Thu 10/167:59 pmPHX - MCI
1 stop21h 54mFrontier
Deal found 9/15$162
This CheapOair deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/227:52 pmSTL - PHX
1 stop24h 29mFrontier
Sat 10/254:41 pmPHX - STL
1 stop14h 41mFrontier
Deal found 9/14$163
This Cheapflightsfares deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Cheapflightsfares is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/212:31 pmMCI - PHX
Nonstop2h 54mFrontier
Sun 11/98:10 amPHX - MCI
Nonstop2h 36mFrontier
Deal found 9/14$164

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Missouri

Fly to

Mesa

Route

Depart

Return

Price

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 10/8

7:52 pm-7:59 am

1 stop14h 07m

Phoenix Sky Harbor Intl

Mon 10/13

9:27 am-9:04 pm

1 stop9h 37m

$172

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Thu 11/13

7:45 pm-9:44 pm

1 stop26h 59m

Phoenix Sky Harbor Intl

Sun 11/16

7:25 am-9:07 am

2 stops24h 42m

$196

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 11/7

5:20 am-7:20 am

Nonstop3h 00m

Phoenix Sky Harbor Intl

Fri 11/7

2:10 pm-5:40 pm

Nonstop2h 30m

$209

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 11/12

6:16 pm-12:36 am

1 stop7h 20m

Phoenix Sky Harbor Intl

Tue 11/18

7:13 am-2:55 pm

1 stop6h 42m

$217

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 10/28

6:30 am-10:40 am

1 stop6h 10m

Phoenix Sky Harbor Intl

Tue 11/4

6:15 pm-12:18 am

1 stop5h 03m

$217

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 10/25

5:55 pm-6:45 pm

Nonstop2h 50m

Phoenix Sky Harbor Intl

Mon 10/27

4:40 pm-11:50 pm

1 stop5h 10m

$219

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Tue 10/14

5:20 pm-9:15 pm

1 stop5h 55m

Phoenix Sky Harbor Intl

Tue 10/28

7:35 pm-12:30 am

Nonstop2h 55m

$219

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Thu 12/4

6:20 pm-12:44 am

1 stop7h 24m

Phoenix Sky Harbor Intl

Fri 12/5

12:59 am-9:58 am

1 stop7h 59m

$223

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 10/31

3:55 pm-9:52 pm

1 stop7h 57m

Phoenix Sky Harbor Intl

Tue 11/4

8:00 am-3:27 pm

1 stop6h 27m

$223

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 12/5

6:20 pm-12:44 am

1 stop7h 24m

Phoenix Sky Harbor Intl

Tue 12/9

7:05 am-2:43 pm

1 stop6h 38m

$223

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/15

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, January is the cheapest month in which you can book a flight from Missouri to Mesa (average of $258). Flying from Missouri to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 16, 2025.

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Missouri to Mesa as you normally would.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated September 16, 2025.

The most flights from USMO to MS9 are scheduled on a Monday (10 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 3h. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $70 on Southwest. Other airlines that offer cheap prices include Frontier from $70 and Delta from $126 one-way.

  • What are the most popular routes from Missouri to Mesa?

  • What are the most reliable airlines from Missouri to Mesa?

    Consider SkyWest Airlines (94%), Alaska Airlines (89%) or American Airlines (89%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $302 for a flight from Missouri to Mesa. The cheapest flight overall is $103 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $139.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, January is the cheapest month in which you can book a flight from Missouri to Mesa (average of $258). Flying from Missouri to Mesa in March is currently the most expensive (average of $337). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 16, 2025.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$100Average$206FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$139Average$225FlexibilityNo cancel feeOn-time65%
Allegiant AirCheapest$140Average$233FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$203Average$468FlexibilityNo cancel feeOn-time69%
DeltaCheapest$234Average$342FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$448FlexibilityNo cancel feeOn-time71%
SouthwestCheapest$252Average$407FlexibilityNo cancel feeOn-time63%

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