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Mesa

$52+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Jan 7 — Jan 141
Wed 1/7
Wed 1/14
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 8, 2025.

This CheapOair deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Mon 12/2910:31 pmPHX - MCI
1 stop20h 19mFrontier
Deal found 12/7$128
This deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/228:45 pmMCI - PHX
1 stop4h 44mFrontier
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/7$136
This CheapOair deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Wed 12/317:00 amPHX - MCI
1 stop11h 50mFrontier
Deal found 12/6$140
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/318:45 pmMCI - PHX
1 stop4h 44mFrontier
Thu 1/17:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/7$141
This Kiwi.com deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:45 pmMCI - PHX
1 stop12h 36mFrontier
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/5$147
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/214:32 pmMCI - PHX
Nonstop3h 02mFrontier
Thu 12/257:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/7$159
This Super.com deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:53 amMCI - PHX
Nonstop3h 02mFrontier
Thu 1/17:20 amPHX - MCI
Nonstop2h 38mFrontier
Deal found 12/5$161
This Kiwi.com deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/1410:44 pmSTL - PHX
1 stop11h 04mFrontier
Tue 12/167:00 amPHX - STL
1 stop26h 14mFrontier
Deal found 12/7$161
This Gotogate deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/238:45 pmMCI - PHX
1 stop12h 36mFrontier
Wed 1/74:41 pmPHX - MCI
1 stop25h 45mFrontier
Deal found 12/6$173
This CheapOair deal was found by Cheapflights users on 12/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/247:43 pmSTL - PHX
1 stop13h 38mFrontier
Tue 12/3010:26 pmPHX - STL
1 stop16h 58mFrontier
Deal found 12/5$183
This CheapOair deal was found by Cheapflights users on 12/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/2110:10 pmSTL - PHX
1 stop24h 06mFrontier
Wed 12/2410:26 pmPHX - STL
1 stop16h 58mFrontier
Deal found 12/6$184
This Frontier deal was found by Cheapflights users on 12/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/198:42 pmSTL - PHX
Nonstop3h 31mFrontier
Sun 12/2110:31 pmPHX - STL
1 stop10h 31mFrontier
Deal found 12/7$186

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated December 8, 2025.

Round-trip from

$112
(Super.com)

One-way from

$52
(Trip.com)

Popular in

March

Cheapest in

November

Average price

$317
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Missouri

Fly to

Mesa

Route

Depart

Return

Price

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Mon 1/5

3:42 pm-11:48 pm

1 stop9h 06m

Phoenix Sky Harbor Intl

Mon 1/12

6:13 am-12:14 pm

1 stop5h 01m

$259

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Wed 1/7

8:45 am-1:30 pm

1 stop5h 45m

Phoenix Sky Harbor Intl

Mon 1/12

1:31 pm-10:00 pm

1 stop7h 29m

$275

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Thu 1/8

5:00 pm-11:40 pm

1 stop7h 40m

Phoenix Sky Harbor Intl

Sun 1/11

6:00 am-4:15 pm

1 stop9h 15m

$284

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Wed 5/20

9:00 am-2:45 pm

1 stop7h 45m

Phoenix Sky Harbor Intl

Wed 5/27

8:30 am-5:53 pm

1 stop7h 23m

$287

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 4/18

8:45 am-2:16 pm

1 stop7h 31m

Phoenix Sky Harbor Intl

Mon 4/27

12:30 pm-10:20 pm

1 stop7h 50m

$287

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 12/20

8:45 pm-12:44 am

1 stop4h 59m

Phoenix Sky Harbor Intl

Fri 1/2

9:31 am-7:50 pm

1 stop9h 19m

$288

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Fri 4/17

5:00 pm-10:08 pm

1 stop7h 08m

Phoenix Sky Harbor Intl

Mon 4/20

12:36 pm-9:59 pm

1 stop7h 23m

$288

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 2/11

6:40 am-11:15 am

1 stop5h 35m

Phoenix Sky Harbor Intl

Sat 2/14

11:55 am-3:30 pm

Nonstop2h 35m

$293

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Thu 1/15

9:40 am-1:40 pm

1 stop5h 00m

Phoenix Sky Harbor Intl

Sat 1/17

5:00 pm-8:50 pm

Nonstop2h 50m

$300

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Tue 2/24

5:55 am-8:35 am

Nonstop3h 40m

Phoenix Sky Harbor Intl

Tue 3/3

12:05 pm-5:10 pm

1 stop4h 05m

$303

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/6

Showing 1-10 of 57 results
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in March is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 8, 2025.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 44% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Friday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 8, 2025.

The most flights from USMO to MS9 are scheduled on a Friday (13 on average). You will have fewer flight options on Tuesday, which is when the least amount of flights are scheduled (6 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 5h 45m. Airlines will cover a distance of 1258 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines to fly from Missouri to Mesa one-way?

    One-way options have recently been found by users for as low as $54 on Frontier. Other airlines that offer cheap prices include Spirit Airlines from $84 and United Airlines from $117 one-way.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider Frontier (86%), American Airlines (70%) or Alaska Airlines (70%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $415 for a flight from Missouri to Mesa. The cheapest flight overall is $67 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $160.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in March is currently the most expensive (average of $188). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Alternative routes for Missouri to Mesa

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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 8, 2025.
AirlineCheapestAverageFlexibilityOn-time
Spirit AirlinesCheapest$91Average$244FlexibilityNo cancel feeOn-time65%
FrontierCheapest$94Average$200FlexibilityNo cancel feeOn-time62%
Allegiant AirCheapest$140Average$196FlexibilityNo cancel feeOn-time88%
DeltaCheapest$168Average$342FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$207Average$391FlexibilityNo cancel feeOn-time63%
United AirlinesCheapest$210Average$438FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$213Average$426FlexibilityNo cancel feeOn-time71%

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