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Mesa

$39+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/27. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Feb 28 — Mar 71
Sat 2/28
Sat 3/7
1 adult, Economy
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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 29, 2026.

This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/24:49 pm
MCI
-
PHX
Nonstop3h 16m
Multiple Airlines
Wed 3/43:05 pm
PHX
-
MCI
1 stop7h 28m
Multiple Airlines
Deal found 1/27$130
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:36 pm
MCI
-
PHX
1 stop12h 36m
Frontier
Sat 2/286:00 am
PHX
-
MCI
1 stop12h 46m
Frontier
Deal found 1/28$132
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/218:36 pm
MCI
-
PHX
1 stop12h 36m
Frontier
Wed 2/259:52 am
PHX
-
MCI
1 stop4h 52m
Frontier
Deal found 1/27$133
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/184:39 pm
MCI
-
PHX
1 stop8h 20m
Frontier
Tue 2/246:51 pm
PHX
-
MCI
1 stop19h 53m
Frontier
Deal found 1/26$134
This Frontier deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/184:39 pm
MCI
-
PHX
1 stop8h 20m
Frontier
Thu 2/199:17 am
PHX
-
MCI
1 stop9h 16m
Frontier
Deal found 1/26$138
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/254:39 pm
MCI
-
PHX
2 stops17h 17m
Frontier
Wed 3/46:00 am
PHX
-
MCI
1 stop8h 44m
Frontier
Deal found 1/28$139
This Kiwi.com deal was found by Cheapflights users on 1/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
MCI
-
PHX
1 stop7h 55m
Multiple Airlines
Tue 3/36:51 pm
PHX
-
MCI
1 stop19h 53m
Multiple Airlines
Deal found 1/27$141
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:24 pm
MCI
-
PHX
1 stop25h 05m
Frontier
Fri 3/610:24 pm
PHX
-
MCI
1 stop20h 31m
Frontier
Deal found 1/26$142
This Frontier deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/269:24 pm
MCI
-
PHX
1 stop11h 18m
Frontier
Thu 3/52:27 pm
PHX
-
MCI
Nonstop2h 32m
Frontier
Deal found 1/28$143
This Kiwi.com deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/148:36 pm
MCI
-
PHX
1 stop12h 36m
Frontier
Tue 2/246:51 pm
PHX
-
MCI
1 stop19h 53m
Frontier
Deal found 1/26$144
This Kiwi.com deal was found by Cheapflights users on 1/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/247:00 am
MCI
-
PHX
1 stop7h 55m
Multiple Airlines
Thu 2/262:27 pm
PHX
-
MCI
Nonstop2h 32m
Multiple Airlines
Deal found 1/28$146
This Frontier deal was found by Cheapflights users on 1/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/238:33 pm
MCI
-
PHX
1 stop5h 08m
Frontier
Thu 2/269:17 am
PHX
-
MCI
1 stop10h 12m
Frontier
Deal found 1/29$148

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated January 29, 2026.

Round-trip from

$130
(Kiwi.com)

One-way from

$39
(Kiwi.com)

Popular in

March

Cheapest in

November

Average price

$359
From Missouri to Mesa
Search Deals
One-way flight from Missouri to Mesa
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($35 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Missouri to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Fly from

Missouri

Fly to

Mesa

Route

Depart

Return

Price

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 2/24

2:24 pm-4:23 pm

Nonstop2h 59m

Phoenix Sky Harbor Intl

Tue 3/3

9:49 am-1:33 pm

Nonstop2h 44m

$199

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 3/3

7:05 am-12:38 pm

1 stop6h 33m

Phoenix Sky Harbor Intl

Wed 3/18

7:05 am-2:54 pm

1 stop5h 49m

$224

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 3/27

1:58 pm-3:16 pm

Nonstop3h 18m

Phoenix Sky Harbor Intl

Sun 3/29

5:30 am-10:02 am

Nonstop2h 32m

$228

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 2/17

3:48 pm-11:29 pm

1 stop8h 41m

Phoenix Sky Harbor Intl

Wed 2/18

7:15 am-2:51 pm

1 stop6h 36m

$229

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Tue 3/10

5:40 pm-11:46 pm

1 stop8h 06m

Phoenix Sky Harbor Intl

Wed 3/18

4:25 pm-11:56 pm

1 stop5h 31m

$239

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sun 3/29

8:40 pm-7:42 am

1 stop13h 02m

Phoenix Sky Harbor Intl

Sun 4/5

8:00 am-12:39 pm

Nonstop2h 39m

$243

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sun 4/5

1:24 pm-2:32 pm

Nonstop3h 08m

Phoenix Sky Harbor Intl

Sun 4/19

4:22 pm-1:30 pm

2 stops19h 08m

$249

SpringfieldPhoenix

SGF - PHX

SGFPHX

Springfield-Branson

Sat 2/21

12:20 pm-7:22 pm

1 stop8h 02m

Phoenix Sky Harbor Intl

Fri 2/27

12:51 am-10:00 am

1 stop8h 09m

$251

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 6/11

11:23 am-5:53 pm

1 stop8h 30m

Phoenix Sky Harbor Intl

Tue 6/16

11:58 pm-10:48 am

1 stop8h 50m

$268

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Mon 3/9

8:38 pm-10:59 am

2 stops16h 21m

Phoenix Sky Harbor Intl

Sun 3/15

9:24 pm-7:53 pm

1 stop20h 29m

$270

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/28

Showing 1-10 of 60 results
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Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in September is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated January 29, 2026.

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 14% on the flight price compared to flying in the morning, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on January 24, 2026.

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Saturday at noon when fares are most often at their lowest. Tuesday mornings flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated January 29, 2026.

The most flights from USMO to MS9 are scheduled on a Thursday (9 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Missouri to Mesa?

    Departing from Missouri to Mesa will take you 2h 59m. Airlines will cover a distance of 1040 mi. This flight may include one or multiple stops.

  • What are the most popular routes from Missouri to Mesa?

    The most popular route from Missouri to Mesa is Kansas City - Phoenix Sky Harbor Intl. You may also consider Lambert-St Louis - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

  • What are the most reliable airlines from Missouri to Mesa?

    Consider American Airlines (87%), Alaska Airlines (87%) or Frontier (80%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

  • What are the cheapest flights from Missouri to Mesa?

    On average you can expect to pay $926 for a flight from Missouri to Mesa. The cheapest flight overall is $104 while the most popular route, (Kansas City - Phoenix Sky Harbor Intl) is currently priced at $138.

  • Can I find deals for flights from Missouri to Mesa that include hotel bookings?

    Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Missouri to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

  • Can I find deals for business class flights from Missouri to Mesa?

    Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Missouri to Mesa?

    Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in September is currently the most expensive (average of $160). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.
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Top 7 airlines flying from Missouri to Mesa

Discover the top 7 airlines that operate flights from Missouri to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 29, 2026.
AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$86Average$196FlexibilityNo cancel feeOn-time62%
Spirit AirlinesCheapest$121Average$200FlexibilityNo cancel feeOn-time65%
DeltaCheapest$138Average$342FlexibilityNo cancel feeOn-timeN/A
Allegiant AirCheapest$140Average$204FlexibilityNo cancel feeOn-time88%
United AirlinesCheapest$148Average$405FlexibilityNo cancel feeOn-time69%
SouthwestCheapest$201Average$386FlexibilityNo cancel feeOn-time63%
American AirlinesCheapest$204Average$426FlexibilityNo cancel feeOn-time71%

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