How long is the flight from Missouri to Mesa?

Departing from Missouri to Mesa will take you 3h 41m. Airlines will cover a distance of 1258 mi. This flight may include one or multiple stops.

In terms of precipitation, rainfall in Mesa ranges from 0.0 - 1.1 inches per month. July is typically the wettest month, when rainfall can reach 1.1 in. June is typically the driest time to visit Mesa when rainfall is around 0.0 in.

If weather is an important factor for your trip to Mesa, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 95.0 F. Travelers looking to avoid the cold should look outside of December, when temperatures are typically at their lowest (around 55.4 F).

What are the most popular routes from Missouri to Mesa?

The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.

What are the cheapest flights from Missouri to Mesa?

On average you can expect to pay $894 for a flight from Missouri to Mesa. The cheapest flight overall is $81 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $213.

What are the most reliable airlines from Missouri to Mesa?

Consider Frontier (88%), American Airlines (79%) or Alaska Airlines (79%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.

Can I find deals for flights from Missouri to Mesa that include hotel bookings?

Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Missouri to Mesa?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.

Can I find deals for business class flights from Missouri to Mesa?

Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$39+ Flights from Missouri to Mesa

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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Wed 12/318:45 pmMCI - PHX

1 stop4h 44mFrontier

Wed 1/77:39 pmPHX - MCI

1 stop22h 47mFrontier

Deal found 12/24

$183

Wed 12/317:43 pmSTL - PHX

1 stop5h 46mFrontier

Wed 1/72:23 pmPHX - STL

1 stop20h 49mFrontier

Deal found 12/23

$183

Wed 12/314:27 pmSTL - PHX

1 stop8h 22mFrontier

Sun 1/412:59 amPHX - STL

1 stop7h 46mFrontier

Deal found 12/24

$204

Wed 12/314:27 pmSTL - PHX

1 stop8h 22mFrontier

Thu 1/110:31 pmPHX - STL

1 stop10h 31mFrontier

Deal found 12/24

$207

Mon 12/298:52 pmSTL - PHX

Nonstop3h 31mFrontier

Thu 1/89:22 pmPHX - STL

1 stop11h 40mFrontier

Deal found 12/25

$215

Mon 12/298:52 pmSTL - PHX

Nonstop3h 31mFrontier

Sat 1/107:57 pmPHX - STL

1 stop14h 42mFrontier

Deal found 12/25

$222

Wed 12/247:43 pmSTL - PHX

1 stop13h 38mFrontier

Wed 1/288:30 amPHX - STL

1 stop5h 16mFrontier

Deal found 12/24

$227

Fri 12/268:42 pmSTL - PHX

Nonstop3h 31mFrontier

Thu 1/19:31 amPHX - STL

1 stop23h 31mFrontier

Deal found 12/24

$231

Fri 12/268:42 pmSTL - PHX

Nonstop3h 31mFrontier

Mon 1/59:58 amPHX - STL

1 stop10h 27mFrontier

Deal found 12/25

$233

Mon 12/298:52 pmSTL - PHX

Nonstop3h 31mFrontier

Mon 1/59:58 amPHX - STL

1 stop10h 27mFrontier

Deal found 12/26

$236

Wed 12/318:45 pmMCI - PHX

1 stop4h 44mFrontier

Sun 1/410:31 pmPHX - MCI

1 stop20h 19mFrontier

Deal found 12/23

$237

Fri 12/268:42 pmSTL - PHX

Nonstop3h 31mFrontier

Mon 12/294:10 pmPHX - STL

Nonstop2h 57mFrontier

Deal found 12/25

$238

Best flights from Missouri to Mesa
Discover carefully curated flight deals from Missouri to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 26, 2025.

Fri 1/168:27 pmMCI - PHX

1 stop17h 30mMultiple Airlines

Mon 1/1910:16 pmPHX - MCI

1 stop24h 17mMultiple Airlines

Deal found 12/25

$189

Mon 1/199:03 pmSTL - PHX

Nonstop3h 41mFrontier

Tue 1/276:42 pmPHX - STL

2 stops19h 04mFrontier

Deal found 12/25

$216

Wed 2/252:30 pmMCI - PHX

2 stops10h 20mDelta

Fri 2/277:59 pmPHX - MCI

1 stop26h 51mDelta

Deal found 12/23

$250

Mon 1/196:00 pmSTL - PHX

1 stop5h 59mUnited Airlines

Sat 1/246:45 amPHX - STL

2 stops8h 18mUnited Airlines

Deal found 12/25

$262

Fri 2/272:49 pmMCI - PHX

1 stop21h 07mAlaska Airlines

Tue 3/34:27 pmPHX - MCI

2 stops20h 28mAlaska Airlines

Deal found 12/25

$355

Sat 3/217:35 pmSGF - PHX

1 stop5h 11mAmerican Airlines

Sat 3/285:22 pmPHX - SGF

1 stop4h 33mAmerican Airlines

Deal found 12/25

$360

Thu 3/2610:47 pmSTL - PHX

Nonstop3h 41mFrontier

Sun 3/295:11 pmPHX - STL

Nonstop2h 53mFrontier

Deal found 12/25

$269

Sat 1/3111:17 amCOU - PHX

2 stops11h 21mUnited Airlines

Wed 2/412:56 pmPHX - COU

1 stop6h 37mUnited Airlines

Deal found 12/25

$274

Wed 3/112:40 pmMCI - PHX

1 stop5h 44mDelta

Wed 3/184:28 pmPHX - MCI

1 stop5h 28mDelta

Deal found 12/25

$279

Sat 1/174:14 pmMCI - PHX

1 stop5h 48mDelta

Wed 1/216:20 amPHX - MCI

2 stops13h 19mDelta

Deal found 12/25

$282

Sat 1/1711:17 amCOU - PHX

1 stop9h 05mUnited Airlines

Sun 1/181:57 pmPHX - COU

1 stop6h 40mUnited Airlines

Deal found 12/25

$294

Thu 2/128:28 pmMCI - PHX

1 stop5h 13mFrontier

Thu 2/191:22 pmPHX - MCI

1 stop5h 11mFrontier

Deal found 12/25

$311

Wed 2/182:49 pmMCI - PHX

1 stop10h 10mAlaska Airlines

Mon 2/238:20 pmPHX - MCI

2 stops19h 02mAlaska Airlines

Deal found 12/25

$355

Tue 1/2011:20 amSTL - PHX

1 stop9h 02mUnited Airlines

Tue 1/272:42 pmPHX - STL

1 stop5h 16mUnited Airlines

Deal found 12/25

$297

Wed 2/182:30 pmMCI - PHX

2 stops10h 20mDelta

Thu 2/262:42 pmPHX - MCI

1 stop8h 08mDelta

Deal found 12/25

$310

Tue 1/203:11 pmSTL - PHX

1 stop8h 48mUnited Airlines

Wed 1/2112:56 pmPHX - STL

1 stop7h 02mUnited Airlines

Deal found 12/25

$297

Thu 1/19:30 amCGI - PHX

1 stop15h 57mMultiple Airlines

Thu 1/86:25 pmPHX - CGI

2 stops25h 10mMultiple Airlines

Deal found 12/25

$405

Sun 3/158:40 pmMCI - PHX

2 stops29h 06mFrontier

Thu 3/1912:54 pmPHX - MCI

1 stop5h 01mFrontier

Deal found 12/25

$339

Sat 4/115:29 pmSTL - PHX

1 stop6h 23mDelta

Tue 4/216:05 amPHX - STL

1 stop6h 33mDelta

Deal found 12/25

$317

Wed 1/216:30 amSTL - PHX

1 stop7h 05mUnited Airlines

Wed 1/217:27 pmPHX - STL

2 stops13h 46mUnited Airlines

Deal found 12/25

$302

Tue 1/203:31 pmSTL - PHX

1 stop6h 31mDelta

Sat 1/246:55 amPHX - STL

1 stop5h 53mDelta

Deal found 12/25

$317

Thu 1/88:52 amJLN - PHX

1 stop8h 05mUnited Airlines

Mon 1/1210:22 amPHX - JLN

1 stop6h 12mUnited Airlines

Deal found 12/24

$304

Fri 1/165:03 pmSGF - PHX

1 stop6h 56mUnited Airlines

Tue 1/209:00 amPHX - SGF

2 stops10h 36mUnited Airlines

Deal found 12/25

$304

Tue 3/106:40 amMCI - PHX

1 stop7h 55mDelta

Sat 3/146:00 amPHX - MCI

1 stop5h 38mDelta

Deal found 12/24

$348

Fri 1/98:45 amCOU - PHX

1 stop5h 45mUnited Airlines

Mon 1/128:10 amPHX - COU

2 stops11h 23mUnited Airlines

Deal found 12/25

$304

Tue 1/204:35 pmSTL - PHX

1 stop6h 39mUnited Airlines

Mon 1/263:35 pmPHX - STL

1 stop5h 25mUnited Airlines

Deal found 12/25

$317

Tue 1/204:35 pmSTL - PHX

1 stop6h 39mUnited Airlines

Thu 1/226:45 amPHX - STL

1 stop5h 31mUnited Airlines

Deal found 12/25

$317

Fri 1/166:15 pmJLN - PHX

1 stop5h 44mUnited Airlines

Sat 1/248:10 amPHX - JLN

1 stop8h 24mUnited Airlines

Deal found 12/26

$322

Wed 3/189:30 amCGI - PHX

2 stops15h 57mMultiple Airlines

Tue 3/246:17 pmPHX - CGI

2 stops17h 08mMultiple Airlines

Deal found 12/24

$775

Tue 1/138:05 amSTL - PHX

1 stop7h 11mUnited Airlines

Sat 1/176:45 amPHX - STL

2 stops9h 58mUnited Airlines

Deal found 12/23

$322

Last-minute flights from Missouri to Mesa
Discover last-minute flight deals from Missouri to Mesa. Data last updated December 26, 2025 and is based on user searches.

Thu 1/111:53 amMCI - PHX

Nonstop3h 02mFrontier

Thu 1/89:16 amPHX - MCI

1 stop9h 10mFrontier

Deal found 12/25

$131

Thu 1/111:53 amMCI - PHX

Nonstop3h 02mFrontier

Mon 1/57:00 amPHX - MCI

1 stop11h 50mFrontier

Deal found 12/24

$152

Thu 1/88:23 pmMCI - PHX

1 stop5h 06mFrontier

Mon 1/128:17 amPHX - MCI

Nonstop2h 38mFrontier

Deal found 12/26

$162

Mon 1/1212:50 pmMCI - PHX

Nonstop3h 02mFrontier

Mon 1/192:46 pmPHX - MCI

Nonstop2h 32mFrontier

Deal found 12/26

$140

Mon 1/128:26 pmMCI - PHX

1 stop5h 03mFrontier

Sun 1/187:30 amPHX - MCI

Nonstop2h 34mFrontier

Deal found 12/24

$150

Wed 1/147:00 amMCI - PHX

1 stop7h 24mMultiple Airlines

Sun 1/187:30 amPHX - MCI

Nonstop2h 34mMultiple Airlines

Deal found 12/24

$157

Thu 1/158:33 pmMCI - PHX

1 stop5h 26mFrontier

Sun 1/187:30 amPHX - MCI

Nonstop2h 34mFrontier

Deal found 12/24

$123

Fri 1/168:27 pmMCI - PHX

1 stop17h 30mFrontier

Sun 1/187:30 amPHX - MCI

Nonstop2h 34mFrontier

Deal found 12/26

$160

Sun 1/1811:49 amMCI - PHX

Nonstop3h 23mMultiple Airlines

Tue 1/2010:15 amPHX - MCI

2 stops12h 18mMultiple Airlines

Deal found 12/25

$144

Sun 1/1811:49 amMCI - PHX

Nonstop3h 23mMultiple Airlines

Wed 1/214:21 pmPHX - MCI

1 stop6h 12mMultiple Airlines

Deal found 12/25

$161

Mon 1/199:03 pmSTL - PHX

Nonstop3h 41mFrontier

Tue 1/273:55 pmPHX - STL

1 stop21h 51mFrontier

Deal found 12/25

$171

Sun 1/258:41 pmMCI - PHX

1 stop12h 31mFrontier

Sun 2/19:22 amPHX - MCI

1 stop9h 29mFrontier

Deal found 12/24

$147

One-way flights from Missouri to Mesa
Search for one-way flight options from Missouri to Mesa. Find affordable one-way fares based on user searches. Data last updated December 26, 2025.

Thu 1/111:53 amMCI - PHX

Nonstop3h 02mFrontier

Deal found 12/25

$39

Wed 2/254:39 pmMCI - PHX

1 stop8h 20mFrontier

Deal found 12/26

$58

Sat 1/243:46 pmSTL - PHX

1 stop9h 07mFrontier

Deal found 12/24

$62

Wed 2/254:51 pmSTL - PHX

1 stop8h 08mFrontier

Deal found 12/23

$64

Wed 1/213:46 pmSTL - PHX

1 stop9h 07mFrontier

Deal found 12/25

$70

Mon 1/268:41 pmMCI - PHX

1 stop17h 59mFrontier

Deal found 12/25

$72

Sun 1/258:41 pmMCI - PHX

1 stop5h 18mFrontier

Deal found 12/26

$75

Mon 2/233:49 pmSTL - PHX

1 stop31h 23mFrontier

Deal found 12/26

$75

Wed 1/143:43 pmSTL - PHX

1 stop8h 46mFrontier

Deal found 12/23

$76

Sat 2/219:41 amSTL - PHX

1 stop13h 31mFrontier

Deal found 12/24

$77

Sat 1/173:43 pmSTL - PHX

1 stop8h 46mFrontier

Deal found 12/25

$80

Tue 1/207:00 amMCI - PHX

2 stops32h 22mMultiple Airlines

Deal found 12/24

$81

Find flight deals from Missouri to Mesa

Round-trip from	$123 (Expedia)
One-way from	$39 (Kiwi.com)
Popular in	March
Cheapest in	November
Average price	$328

From Missouri to Mesa

Search Deals

One-way flight from Missouri to Mesa

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($37 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 1% potential price decrease ($8 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Fri 1/16

8:27 pm-12:57 pm

1 stop17h 30m

Phoenix Sky Harbor Intl

Mon 1/19

10:16 pm-11:33 pm

1 stop24h 17m

$189

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 1/19

9:03 pm-11:44 pm

Nonstop3h 41m

Phoenix Sky Harbor Intl

Tue 1/27

6:42 pm-2:46 pm

2 stops19h 04m

$216

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 2/25

2:30 pm-11:50 pm

2 stops10h 20m

Phoenix Sky Harbor Intl

Fri 2/27

7:59 pm-11:50 pm

1 stop26h 51m

$250

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Mon 1/19

6:00 pm-10:59 pm

1 stop5h 59m

Phoenix Sky Harbor Intl

Sat 1/24

6:45 am-4:03 pm

2 stops8h 18m

$262

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Thu 3/26

10:47 pm-12:28 am

Nonstop3h 41m

Phoenix Sky Harbor Intl

Sun 3/29

5:11 pm-10:04 pm

Nonstop2h 53m

$269

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 1/31

11:17 am-9:38 pm

2 stops11h 21m

Phoenix Sky Harbor Intl

Wed 2/4

12:56 pm-8:33 pm

1 stop6h 37m

$274

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Wed 3/11

2:40 pm-6:24 pm

1 stop5h 44m

Phoenix Sky Harbor Intl

Wed 3/18

4:28 pm-11:56 pm

1 stop5h 28m

$279

Kansas CityPhoenix

MCI - PHX

MCIPHX

Kansas City

Sat 1/17

4:14 pm-9:02 pm

1 stop5h 48m

Phoenix Sky Harbor Intl

Wed 1/21

6:20 am-8:39 pm

2 stops13h 19m

$282

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Sat 1/17

11:17 am-7:22 pm

1 stop9h 05m

Phoenix Sky Harbor Intl

Sun 1/18

1:57 pm-9:37 pm

1 stop6h 40m

$294

St. LouisPhoenix

STL - PHX

STLPHX

Lambert-St Louis

Tue 1/20

11:20 am-7:22 pm

1 stop9h 02m

Phoenix Sky Harbor Intl

Tue 1/27

2:42 pm-8:58 pm

1 stop5h 16m

$297

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/24

Showing 1-10 of 55 results

...

Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in March is currently the most expensive (average of $178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MO to MS9?

It’s typically best to fly out from Missouri to Mesa in the evening. Doing so could potentially save you 45% on the flight price compared to flying at noon, which is usually more expensive.

What is the cheapest day to fly from Missouri to Mesa?

Travelers seeking maximum savings on their Missouri to Mesa flight should consider departing on Friday evenings when fares are most often at their lowest. Wednesday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Weekly flight availability from Missouri to Mesa

The most flights from USMO to MS9 are scheduled on a Friday (13 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (2 on average).

Related info for your journey

How long is the flight from Missouri to Mesa?
Departing from Missouri to Mesa will take you 3h 41m. Airlines will cover a distance of 1258 mi. This flight may include one or multiple stops.
What are the most popular routes from Missouri to Mesa?
The most popular route from Missouri to Mesa is Lambert-St Louis - Phoenix Sky Harbor Intl. You may also consider Kansas City - Phoenix Sky Harbor Intl or Springfield-Branson - Phoenix Sky Harbor Intl.
What are the most reliable airlines from Missouri to Mesa?
Consider Frontier (88%), American Airlines (79%) or Alaska Airlines (79%) when booking your flight. These represent the most reliable airlines when flying from Missouri to Mesa.
What are the cheapest flights from Missouri to Mesa?
On average you can expect to pay $894 for a flight from Missouri to Mesa. The cheapest flight overall is $81 while the most popular route, (Lambert-St Louis - Phoenix Sky Harbor Intl) is currently priced at $213.
Can I find deals for flights from Missouri to Mesa that include hotel bookings?
Yes. In addition to deals on Missouri to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Missouri to Mesa?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Missouri to Mesa.
Can I find deals for business class flights from Missouri to Mesa?
Yes. Cheapflights offers flight deals from Missouri to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Missouri to Mesa?
Currently, December is the cheapest month in which you can book a flight from Missouri to Mesa (average of $98). Flying from Missouri to Mesa in March is currently the most expensive (average of $178). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 7 airlines flying from Missouri to Mesa

Airline	Cheapest	Average	Flexibility	On-time
Spirit Airlines	Cheapest$91	Average$232	FlexibilityNo cancel fee	On-time65%
Frontier	Cheapest$93	Average$199	FlexibilityNo cancel fee	On-time62%
Allegiant Air	Cheapest$140	Average$195	FlexibilityNo cancel fee	On-time88%
Delta	Cheapest$168	Average$344	FlexibilityNo cancel fee	On-timeN/A
Southwest	Cheapest$203	Average$388	FlexibilityNo cancel fee	On-time63%
American Airlines	Cheapest$209	Average$424	FlexibilityNo cancel fee	On-time71%
United Airlines	Cheapest$210	Average$437	FlexibilityNo cancel fee	On-time69%

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$39+ Cheap flights from Missouri to Mesa, AZ

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/1. Fares are subject to change and may not be available on all flights or dates of travel.

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Cheap flight deals from Missouri to Mesa

Cheapest flights from Missouri to MesaExplore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.

Find flight deals from Missouri to Mesa

Keep the following information in mind while searching for Missouri to Mesa flight deals. Data was last updated December 26, 2025.

Round-trip from

One-way from

Popular in

Cheapest in

Average price

Cheapflights Fare Finder

Use the filters below to find and compare flights from Missouri to Mesa that are best for you.

Best time to book a flight from Missouri to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Missouri with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Missouri to Mesa

What is the cheapest month to book a flight from Missouri to Mesa?

What is the cheapest time of day to fly from MO to MS9?

Find hourly flight availability from Missouri to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 26, 2025.

What is the cheapest day to fly from Missouri to Mesa?

Use this chart to determine the cheapest time to fly round-trip from Missouri to Mesa. Price data was last updated on December 16, 2024.

Weekly flight availability from Missouri to Mesa

Explore weekly flight availability from Missouri to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated December 26, 2025.

Related info for your journey

Find useful and relevant information for your journey from Missouri to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

How long is the flight from Missouri to Mesa?

What are the most popular routes from Missouri to Mesa?

What are the most reliable airlines from Missouri to Mesa?

What are the cheapest flights from Missouri to Mesa?

Can I find deals for flights from Missouri to Mesa that include hotel bookings?

How can I find direct flights from Missouri to Mesa?

Can I find deals for business class flights from Missouri to Mesa?

What is the cheapest month to book a flight from Missouri to Mesa?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Missouri to Mesa

See prices for flight routes from nearby airports that may be better suited for you.

Top 7 airlines flying from Missouri to Mesa

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Cheapest flights from Missouri to Mesa
Explore the most affordable flight options available from Missouri to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 26, 2025.