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Mesa

$299+ Cheap flights from Columbia, MO (COU) to Mesa, AZ

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/1. Fares are subject to change and may not be available on all flights or dates of travel.
COU — PHX
Jun 4 — Jun 111
Thu 6/4
Thu 6/11
1 adult, Economy
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Cheap flight deals from Columbia to Mesa

Cheapest flights from Columbia to Mesa
Explore the most affordable flight options available from Columbia to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 5, 2026.

This American Airlines deal was found by Cheapflights users on 5/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/76:32 pm
COU
-
PHX
1 stop7h 42m
American Airlines
Sun 7/1212:50 am
PHX
-
COU
1 stop7h 12m
American Airlines
Deal found 5/4$299
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/186:47 pm
COU
-
PHX
1 stop7h 33m
American Airlines
Sat 6/2012:50 am
PHX
-
COU
1 stop7h 16m
American Airlines
Deal found 5/5$328
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/246:47 pm
COU
-
PHX
1 stop7h 33m
American Airlines
Sat 6/2712:50 am
PHX
-
COU
1 stop7h 16m
American Airlines
Deal found 5/5$340
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:16 pm
COU
-
PHX
1 stop8h 28m
United Airlines
Tue 10/2010:26 am
PHX
-
COU
2 stops8h 54m
United Airlines
Deal found 5/5$354
This United Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/13:25 pm
COU
-
PHX
1 stop9h 02m
United Airlines
Sat 7/41:28 pm
PHX
-
COU
1 stop8h 05m
United Airlines
Deal found 5/5$360
This American Airlines deal was found by Cheapflights users on 5/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:25 am
COU
-
PHX
1 stop7h 40m
American Airlines
Sat 5/233:15 pm
PHX
-
COU
1 stop5h 10m
American Airlines
Deal found 5/5$384
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/256:32 pm
COU
-
PHX
1 stop7h 42m
American Airlines
Mon 6/11:15 am
PHX
-
COU
1 stop6h 40m
American Airlines
Deal found 5/3$389
This United Airlines deal was found by Cheapflights users on 5/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:00 am
COU
-
PHX
1 stop9h 19m
United Airlines
Fri 8/1411:28 am
PHX
-
COU
1 stop8h 21m
United Airlines
Deal found 5/1$418
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/25:19 pm
COU
-
PHX
1 stop5h 49m
American Airlines
Wed 6/101:15 am
PHX
-
COU
1 stop6h 51m
American Airlines
Deal found 5/3$430
This American Airlines deal was found by Cheapflights users on 5/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:43 pm
COU
-
PHX
1 stop5h 22m
American Airlines
Wed 5/273:15 pm
PHX
-
COU
1 stop5h 10m
American Airlines
Deal found 5/3$433

Find flight deals from Columbia to Mesa

Keep the following information in mind while searching for Columbia to Mesa flight deals. Data was last updated May 5, 2026.

Round-trip from

$299
(American Airlines)

Popular in

October

Cheapest in

January

Average price

$411
From Columbia Regional to Mesa
Search Deals
Highest demand for flights based on searches. 21% potential increase in price ($139 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($33 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in May 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
Use the filters below to find and compare flights from Columbia to Mesa that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Wed 7/1

3:25 pm-10:27 pm

1 stop9h 02m

Phoenix Sky Harbor Intl

Sat 7/4

1:28 pm-11:33 pm

1 stop8h 05m

$360
Quickest round-trip

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Thu 6/18

6:47 pm-12:20 am

1 stop7h 33m

Phoenix Sky Harbor Intl

Sat 6/20

12:50 am-10:06 am

1 stop7h 16m

$369

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 8/7

8:00 am-9:00 am

2 stops27h 00m

Phoenix Sky Harbor Intl

Fri 8/14

9:08 am-9:49 pm

2 stops10h 41m

$541

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Tue 7/7

9:14 am-11:30 pm

3 stops16h 16m

Phoenix Sky Harbor Intl

Mon 7/13

6:54 pm-10:13 am

2 stops13h 19m

$598
Cheapest one-way
Quickest one-way

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 5/29

6:32 pm-6:42 am

1 stop14h 10m

$307

ColumbiaPhoenix

COU - PHX

COUPHX

Columbia Regional

Fri 5/29

3:25 pm-8:30 pm

3 stops31h 05m

$550

Flights are sorted by cheapest round-trip flights first.

Deals found on 5/3

Sorted by cheapest first

Best time to book a flight from Columbia to Mesa

Have a flexible travel schedule? Discover the best time to fly to Mesa from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Mesa

How much does it cost to fly round-trip from Columbia, Missouri to Mesa?

Reviews of airlines servicing Mesa

Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated May 5, 2026.
Get a feel of what it's like to fly with United Airlines and American Airlines from Columbia to Mesa by reading reviews from past customers. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,683 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
United Airlines
7.4
Good
9,683 reviews
United Airlines
7.4
Good
9,683 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.
American Airlines
7.1
Good
11,668 reviews
United Airlines
7.4
Good
9,683 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
8.0
Excellent

Anonymous,Apr 2026

DFW - EWR

The flight was on time. Crew was friendly. Will fly again. The seats was comfortable.

Related info for your journey

Find useful and relevant information for your journey from Columbia to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Mesa?

    For a flight from Columbia to Mesa, you will be flying from Columbia Regional. Columbia Regional (COU) is just 11.1 mi from the center of the city. Columbia Regional is the only Columbia airport and it handles 0 outbound flights to Mesa per day. 2 airlines have flights to Mesa from Columbia Regional on a regular basis.

  • How long is the flight from Columbia, Missouri to Mesa?

    For as low as $369, United Airlines can have you in Mesa from Columbia, Missouri in 7h 33m. There are 1161 mi between Columbia, Missouri and Mesa. Both multi-stop and nonstop flights can be found to your destination and back.

  • Can I find deals for flights from Columbia to Mesa that include hotel bookings?

    Yes. In addition to deals on Columbia to Mesa flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Mesa?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Mesa.

  • Can I find deals for business class flights from Columbia to Mesa?

    Yes. Cheapflights offers flight deals from Columbia to Mesa by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Columbia to Mesa

Discover the top 2 airlines that operate flights from Columbia to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 5, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$248Average$348FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$420Average$610FlexibilityNo cancel feeOn-time71%

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