$82+ Cheap flights from Mesa, AZ to St. Louis (STL)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — STL
Oct 10 — Oct 171
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Lambert-St Louis are usually found in January or November, booked 10 days in advance, depart on a Saturday or Friday and return on a Wednesday
Cheap flight deals from Mesa to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to St. LouisExplore the most affordable flight options available from Mesa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
Explore the most affordable flight options available from Mesa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
2 stops8h 43m
Mon 10/261:30 pm -
1 stop7h 03m
Deal found 9/9![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:24 pm -
1 stop14h 08m
Mon 10/58:10 pm -
1 stop13h 50m
Deal found 9/10![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:56 pm -
1 stop20h 21m
Thu 10/84:30 pm -
1 stop30h 12m
Deal found 9/9![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:24 pm -
1 stop13h 53m
Fri 10/28:10 pm -
1 stop13h 50m
Deal found 9/9![Frontier logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:56 pm -
2 stops36h 36m
Wed 10/144:19 pm -
1 stop9h 29m
Deal found 9/9![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:56 pm -
1 stop20h 21m
Fri 10/95:53 pm -
1 stop7h 06m
Deal found 9/9![Frontier logo]()
$281
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:51 pm -
1 stop20h 24m
Sun 11/11:28 pm -
1 stop5h 59m
Deal found 9/8![Frontier logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:15 am -
1 stop7h 09m
Thu 10/2912:14 pm -
1 stop12h 46m
Deal found 9/9![Frontier logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:24 pm -
1 stop13h 53m
Sat 10/38:10 pm -
1 stop5h 33m
Deal found 9/9![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:28 pm -
1 stop14h 07m
Mon 10/58:10 pm -
1 stop13h 50m
Deal found 9/9![Frontier logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:24 pm -
1 stop13h 53m
Wed 10/78:10 pm -
1 stop5h 33m
Deal found 9/9![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:15 am -
1 stop8h 02m
Sat 10/312:17 pm -
2 stops10h 00m
Deal found 9/9![Frontier logo]()
$288
Best flights from Mesa to St. LouisDiscover carefully curated flight deals from Mesa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
Discover carefully curated flight deals from Mesa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 10, 2026.
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/225:10 am -
Nonstop2h 50m
Mon 10/265:05 am -
Nonstop3h 25m
Deal found 9/9![Southwest logo]()
$397
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/85:27 pm -
1 stop5h 17m
Tue 10/137:00 pm -
1 stop5h 43m
Deal found 9/9![Delta logo]()
$417
This Alaska Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3110:12 am -
2 stops27h 13m
Mon 11/27:00 am -
2 stops13h 40m
Deal found 9/9![Alaska Airlines logo]()
$459
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/295:40 pm -
Nonstop3h 00m
Wed 10/76:20 am -
Nonstop3h 20m
Deal found 9/8![Southwest logo]()
$397
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:30 pm -
Nonstop2h 55m
Sun 11/18:30 am -
1 stop6h 05m
Deal found 9/8![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/71:05 pm -
1 stop4h 50m
Sun 10/116:05 am -
Nonstop3h 20m
Deal found 9/9![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/65:45 am -
Nonstop2h 45m
Sun 11/89:45 pm -
Nonstop3h 25m
Deal found 9/8![Southwest logo]()
$451
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/168:00 am -
1 stop4h 45m
Tue 10/208:50 pm -
Nonstop3h 20m
Deal found 9/5![Southwest logo]()
$453
This Southwest deal was found by Cheapflights users on 9/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/135:50 am -
1 stop5h 00m
Mon 10/265:50 pm -
Nonstop3h 20m
Deal found 9/5![Southwest logo]()
$457
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/285:00 am -
Nonstop2h 50m
Thu 10/15:05 am -
Nonstop3h 25m
Deal found 9/6![Southwest logo]()
$469
This Southwest deal was found by Cheapflights users on 9/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
Nonstop2h 55m
Thu 10/227:40 pm -
1 stop5h 50m
Deal found 9/6![Southwest logo]()
$479
Last-minute flights from Mesa to St. LouisDiscover last-minute flight deals from Mesa to St. Louis. Data last updated September 10, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to St. Louis. Data last updated September 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:24 pm -
1 stop13h 53m
Sat 10/38:10 pm -
1 stop5h 33m
Deal found 9/9![Frontier logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/277:24 pm -
1 stop13h 53m
Wed 10/78:10 pm -
1 stop5h 33m
Deal found 9/9![Frontier logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/287:24 pm -
1 stop14h 08m
Mon 10/58:10 pm -
1 stop13h 50m
Deal found 9/10![Frontier logo]()
$276
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/305:28 pm -
1 stop14h 07m
Mon 10/58:10 pm -
1 stop13h 50m
Deal found 9/9![Frontier logo]()
$286
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:56 pm -
1 stop20h 21m
Thu 10/84:30 pm -
1 stop30h 12m
Deal found 9/9![Frontier logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/17:24 pm -
1 stop13h 53m
Fri 10/28:10 pm -
1 stop13h 50m
Deal found 9/9![Frontier logo]()
$278
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/18:56 pm -
1 stop20h 21m
Fri 10/95:53 pm -
1 stop7h 06m
Deal found 9/9![Frontier logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/29:15 am -
1 stop8h 02m
Sat 10/312:17 pm -
2 stops10h 00m
Deal found 9/9![Frontier logo]()
$288
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/58:56 pm -
2 stops36h 36m
Wed 10/144:19 pm -
1 stop9h 29m
Deal found 9/9![Frontier logo]()
$280
This Expedia deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:51 pm -
1 stop20h 24m
Sun 11/11:28 pm -
1 stop5h 59m
Deal found 9/8![Frontier logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/196:15 am -
2 stops8h 43m
Mon 10/261:30 pm -
1 stop7h 03m
Deal found 9/9![Frontier logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/216:15 am -
1 stop7h 09m
Thu 10/2912:14 pm -
1 stop12h 46m
Deal found 9/9![Frontier logo]()
$284
One-way flights from Mesa to St. LouisSearch for one-way flight options from Mesa to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
Search for one-way flight options from Mesa to St. Louis. Find affordable one-way fares based on user searches. Data last updated September 10, 2026.
This Super.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/73:21 pm -
1 stop6h 38m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$82
This Super.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/317:15 am -
1 stop9h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$87
This Mytrip deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/293:21 pm -
1 stop25h 56m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/8![Frontier logo]()
$88
This Kiwi.com deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/710:59 am -
1 stop6h 55m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/10![Frontier logo]()
$95
This Super.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/228:51 pm -
1 stop20h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$104
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/117:15 am -
1 stop7h 08m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/109:59 pm -
1 stop16h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$107
This Priceline deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/146:15 am -
1 stop7h 09m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/612:25 pm -
2 stops22h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$112
This Frontier deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:09 am -
1 stop8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$113
This Super.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/158:51 pm -
1 stop20h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$114
This Trip.com deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/85:13 pm -
1 stop24h 41m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/9![Frontier logo]()
$118
Find flight deals from Mesa to St. Louis
Keep the following information in mind while searching for Mesa to St. Louis flight deals. Data was last updated September 10, 2026.
Round-trip from | $275 (Kiwi.com) |
|---|---|
One-way from | $82 (Super.com) |
Popular in | June |
Cheapest in | January |
Average price | $366 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
Use the filters below to find and compare flights from Mesa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Mon 10/19
6:30 pm-11:25 pm
Nonstop2h 55m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Sat 11/7
6:00 am-9:50 am
Nonstop2h 50m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Tue 12/8
8:35 am-12:30 pm
Nonstop2h 55m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Sat 10/31
11:35 am-4:25 pm
Nonstop2h 50m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Mon 12/7
5:45 am-9:35 am
Nonstop2h 50m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$199
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Wed 10/14
12:55 pm-7:45 pm
1 stop4h 50m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$209
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Fri 10/30
8:25 pm-1:20 am
Nonstop2h 55m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$209
Quickest round-trip
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Tue 3/9
6:05 pm-9:50 pm
Nonstop2h 45m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$213
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Sat 11/21
5:10 am-9:00 am
Nonstop2h 50m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$213
PhoenixSt. Louis
PHX Phoenix Sky Harbor Intl - STL Lambert-St Louis
PHXSTL
Phoenix Sky Harbor Intl
Wed 1/13
5:50 am-9:35 am
Nonstop2h 45m
Lambert-St Louis
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$213
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from Mesa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mesa with our price prediction graph.
PHX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to St. Louis
MS9-STL
PHX-STL
What is the cheapest time of day to fly from MS9 to STL?
Find hourly flight availability from Mesa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 10, 2026.
A simple way to save on the total cost of your ticket is to fly from Mesa to St. Louis in the afternoon. If you’re flexible enough to do this you can expect to save up to 15% on your trip compared to booking a flight at noon.
How much does it cost to fly round-trip from Mesa to St. Louis?
Airfare is below average for this route at the moment.
Mesa to St. Louis flights typically cost between $325 and $404 in October.The cheapest round-trip price found within the last 5 days was $275 on Frontier (Oct 19-Oct 26).
What is the cheapest day to fly from Mesa to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Mesa to St. Louis. Price data was last updated on September 5, 2026.
Travelers seeking maximum savings on their Mesa to St. Louis flight should consider departing on Friday at noon when fares are most often at their lowest. Sunday at noon flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated September 10, 2026.
Read reviews from past customers who have flown Southwest,American Airlines, andFrontier from Mesa to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Crew
8.6
Entertainment
7.5
Overall
8.0
Food
7.0
Comfort
8.0
Boarding
8.1
Reviews
1 / 20
10.0
ExcellentCourtney,Sep 2026
DEN - STL
Related info for your journey
Find useful and relevant information for your journey from Mesa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsFairview Heights
O'Fallon
Fenton
Swansea
Eureka
Maryland Heights
Collinsville
Wentzville
Edwardsville
Glencoe
Chesterfield
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Complete your trip
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Mesa and St. Louis flights
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Other flights to St. Louis
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Mesa to St. Louis flights
Consider these flights traveling from Mesa to St. Louis.
Top 3 airlines flying from Mesa to St. Louis
Discover the top 3 airlines that operate flights from Mesa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$101 | Average$244 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$229 | Average$385 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$285 | Average$423 | FlexibilityNo cancel fee | On-time63% |