$86+ Cheap flights from Mesa, AZ to St. Louis (STL)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/6. Fares are subject to change and may not be available on all flights or dates of travel.
PHX — STL
Jul 4 — Jul 111
Round-trip
1 adult, Economy
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Find cheap flights from Mesa to St. Louis with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Mesa to Lambert-St Louis are usually found in October or January, booked 25 days in advance, depart on a Friday or Saturday and return on a Wednesday
Cheap flight deals from Mesa to St. Louis
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mesa to St. LouisExplore the most affordable flight options available from Mesa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
Explore the most affordable flight options available from Mesa to St. Louis. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 4, 2026.
This CheapOair deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/267:45 am
PHX
- STL
1 stop8h 23m
Frontier
Sun 8/308:21 pm
STL
- PHX
1 stop17h 03m
Frontier
Deal found 5/31![Frontier logo]()
$268
This Super.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:24 am
PHX
- STL
1 stop6h 32m
Frontier
Sat 7/187:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 6/1![Frontier logo]()
$269
This Frontier deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:24 am
PHX
- STL
1 stop9h 54m
Frontier
Sat 7/47:38 pm
STL
- PHX
1 stop5h 51m
Frontier
Deal found 5/31![Frontier logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:35 am
PHX
- STL
2 stops29h 48m
Frontier
Tue 7/288:08 pm
STL
- PHX
1 stop16h 03m
Frontier
Deal found 6/2![Frontier logo]()
$272
This CheapOair deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/58:05 am
PHX
- STL
1 stop13h 34m
Frontier
Tue 11/105:32 pm
STL
- PHX
1 stop25h 18m
Frontier
Deal found 6/4![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:23 pm
PHX
- STL
1 stop7h 34m
Frontier
Tue 7/143:41 pm
STL
- PHX
1 stop22h 45m
Frontier
Deal found 6/3![Frontier logo]()
$274
This Super.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:19 am
PHX
- STL
1 stop6h 04m
Frontier
Mon 8/37:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 6/1![Frontier logo]()
$275
This Frontier deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:23 pm
PHX
- STL
1 stop7h 34m
Frontier
Tue 7/288:08 pm
STL
- PHX
1 stop5h 24m
Frontier
Deal found 6/3![Frontier logo]()
$276
This Frontier deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:21 am
PHX
- STL
1 stop6h 02m
Frontier
Mon 7/67:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 5/31![Frontier logo]()
$277
This CheapOair deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:32 pm
PHX
- STL
1 stop10h 46m
Frontier
Wed 7/158:08 pm
STL
- PHX
1 stop13h 32m
Frontier
Deal found 6/4![Frontier logo]()
$280
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/74:39 pm
PHX
- STL
1 stop20h 17m
Frontier
Sun 8/93:41 pm
STL
- PHX
1 stop22h 45m
Frontier
Deal found 6/2![Frontier logo]()
$281
This Expedia deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:24 am
PHX
- STL
1 stop9h 54m
Frontier
Wed 7/15:06 pm
STL
- PHX
1 stop7h 14m
Frontier
Deal found 5/30![Frontier logo]()
$282
Best flights from Mesa to St. LouisDiscover carefully curated flight deals from Mesa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
Discover carefully curated flight deals from Mesa to St. Louis that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated June 4, 2026.
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/15:00 am
PHX
- STL
Nonstop2h 50m
Southwest
Tue 7/76:10 am
STL
- PHX
Nonstop3h 10m
Southwest
Deal found 5/31![Southwest logo]()
$375
This American Airlines deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:54 pm
PHX
- STL
Nonstop3h 03m
American Airlines
Wed 7/18:14 pm
STL
- PHX
1 stop6h 06m
American Airlines
Deal found 5/30![American Airlines logo]()
$457
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/105:00 am
PHX
- STL
Nonstop2h 50m
Southwest
Mon 7/135:45 am
STL
- PHX
Nonstop3h 10m
Southwest
Deal found 6/4![Southwest logo]()
$377
This Southwest deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/307:25 am
PHX
- STL
Nonstop2h 55m
Southwest
Thu 7/25:45 am
STL
- PHX
Nonstop3h 10m
Southwest
Deal found 6/1![Southwest logo]()
$415
This Southwest deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/277:25 am
PHX
- STL
Nonstop2h 55m
Southwest
Mon 8/316:00 am
STL
- PHX
Nonstop3h 15m
Southwest
Deal found 6/2![Southwest logo]()
$423
This Southwest deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/286:55 pm
PHX
- STL
Nonstop2h 55m
Southwest
Sun 10/49:45 pm
STL
- PHX
Nonstop3h 20m
Southwest
Deal found 6/3![Southwest logo]()
$429
This Southwest deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/278:55 pm
PHX
- STL
Nonstop3h 00m
Southwest
Thu 7/309:45 pm
STL
- PHX
Nonstop3h 15m
Southwest
Deal found 5/31![Southwest logo]()
$435
This Southwest deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/25:00 am
PHX
- STL
Nonstop2h 50m
Southwest
Sat 7/42:15 pm
STL
- PHX
Nonstop3h 10m
Southwest
Deal found 6/4![Southwest logo]()
$447
This Southwest deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/228:55 pm
PHX
- STL
Nonstop2h 55m
Southwest
Wed 7/19:15 pm
STL
- PHX
Nonstop3h 10m
Southwest
Deal found 5/30![Southwest logo]()
$447
Last-minute flights from Mesa to St. LouisDiscover last-minute flight deals from Mesa to St. Louis. Data last updated June 4, 2026 and is based on user searches.
Discover last-minute flight deals from Mesa to St. Louis. Data last updated June 4, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 5/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/226:24 am
PHX
- STL
1 stop9h 54m
Frontier
Wed 7/15:06 pm
STL
- PHX
1 stop7h 14m
Frontier
Deal found 5/30![Frontier logo]()
$282
This Frontier deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/2411:21 am
PHX
- STL
1 stop6h 02m
Frontier
Mon 7/67:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 5/31![Frontier logo]()
$277
This Frontier deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:24 am
PHX
- STL
1 stop9h 54m
Frontier
Sat 7/47:38 pm
STL
- PHX
1 stop5h 51m
Frontier
Deal found 5/31![Frontier logo]()
$270
This Expedia deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/256:53 pm
PHX
- STL
1 stop22h 00m
Frontier
Mon 6/297:38 pm
STL
- PHX
1 stop19h 42m
Frontier
Deal found 5/31![Frontier logo]()
$284
This Orbitz deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Orbitz is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/266:53 pm
PHX
- STL
1 stop22h 00m
Frontier
Tue 7/78:08 pm
STL
- PHX
1 stop21h 35m
Frontier
Deal found 6/1![Frontier logo]()
$283
This Frontier deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/110:32 pm
PHX
- STL
1 stop10h 46m
Frontier
Wed 7/157:03 pm
STL
- PHX
1 stop6h 02m
Frontier
Deal found 6/1![Frontier logo]()
$273
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:23 pm
PHX
- STL
1 stop7h 34m
Frontier
Tue 7/143:41 pm
STL
- PHX
1 stop22h 45m
Frontier
Deal found 6/3![Frontier logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 6/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1411:35 am
PHX
- STL
2 stops29h 48m
Frontier
Tue 7/288:08 pm
STL
- PHX
1 stop16h 03m
Frontier
Deal found 6/2![Frontier logo]()
$272
This Super.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/166:24 am
PHX
- STL
1 stop6h 32m
Frontier
Sat 7/187:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 6/1![Frontier logo]()
$269
This Frontier deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2411:23 pm
PHX
- STL
1 stop7h 34m
Frontier
Tue 7/288:08 pm
STL
- PHX
1 stop5h 24m
Frontier
Deal found 6/3![Frontier logo]()
$276
This Super.com deal was found by Cheapflights users on 6/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:19 am
PHX
- STL
1 stop6h 04m
Frontier
Mon 8/37:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Deal found 6/1![Frontier logo]()
$275
One-way flights from Mesa to St. LouisSearch for one-way flight options from Mesa to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
Search for one-way flight options from Mesa to St. Louis. Find affordable one-way fares based on user searches. Data last updated June 4, 2026.
This Kiwi.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:24 am
PHX
- STL
1 stop6h 32m
Frontier
Deal found 6/3![Frontier logo]()
$86
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:57 am
PHX
- STL
1 stop6h 26m
Frontier
Deal found 6/4![Frontier logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/27:45 am
PHX
- STL
2 stops33h 38m
Frontier
Deal found 6/4![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:57 am
PHX
- STL
1 stop6h 26m
Frontier
Deal found 6/4![Frontier logo]()
$98
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/32:16 pm
PHX
- STL
2 stops27h 07m
Frontier
Deal found 6/4![Frontier logo]()
$101
This Trip.com deal was found by Cheapflights users on 6/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/811:23 pm
PHX
- STL
1 stop16h 14m
Frontier
Deal found 6/3![Frontier logo]()
$102
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:32 pm
PHX
- STL
1 stop18h 19m
Frontier
Deal found 6/4![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1510:55 pm
PHX
- STL
1 stop10h 56m
Frontier
Deal found 6/4![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 6/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:23 pm
PHX
- STL
1 stop16h 14m
Frontier
Deal found 6/4![Frontier logo]()
$110
This Super.com deal was found by Cheapflights users on 5/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:27 pm
PHX
- STL
1 stop19h 09m
Frontier
Deal found 5/31![Frontier logo]()
$115
Find flight deals from Mesa to St. Louis
Keep the following information in mind while searching for Mesa to St. Louis flight deals. Data was last updated June 4, 2026.
Round-trip from | $268 (CheapOair) |
|---|---|
One-way from | $86 (Kiwi.com) |
Popular in | March |
Cheapest in | October |
Average price | $405 |
Cheapflights Fare Finder
Customize your flight search to find flights from Mesa to St. Louis that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
Use the filters below to find and compare flights from Mesa to St. Louis that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Wed 7/1
5:00 am-9:50 am
Nonstop2h 50m
Lambert-St Louis
Tue 7/7
6:10 am-7:20 am
Nonstop3h 10m
$375
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Fri 7/10
5:00 am-9:50 am
Nonstop2h 50m
Lambert-St Louis
Mon 7/13
5:45 am-6:55 am
Nonstop3h 10m
$377
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Tue 6/30
7:25 am-12:20 pm
Nonstop2h 55m
Lambert-St Louis
Thu 7/2
5:45 am-6:55 am
Nonstop3h 10m
$415
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Thu 8/27
7:25 am-12:20 pm
Nonstop2h 55m
Lambert-St Louis
Mon 8/31
6:00 am-7:15 am
Nonstop3h 15m
$423
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Mon 9/28
6:55 pm-11:50 pm
Nonstop2h 55m
Lambert-St Louis
Sun 10/4
9:45 pm-11:05 pm
Nonstop3h 20m
$429
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Mon 7/27
8:55 pm-1:55 am
Nonstop3h 00m
Lambert-St Louis
Thu 7/30
9:45 pm-11:00 pm
Nonstop3h 15m
$435
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Thu 7/2
5:00 am-9:50 am
Nonstop2h 50m
Lambert-St Louis
Sat 7/4
2:15 pm-3:25 pm
Nonstop3h 10m
$447
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Mon 6/22
8:55 pm-1:50 am
Nonstop2h 55m
Lambert-St Louis
Wed 7/1
9:15 pm-10:25 pm
Nonstop3h 10m
$447
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Mon 6/22
6:54 pm-11:57 pm
Nonstop3h 03m
Lambert-St Louis
Wed 7/1
8:14 pm-12:20 am
1 stop6h 06m
$457
Cheapest one-way
PhoenixSt. Louis
PHX - STL
PHXSTL
Phoenix Sky Harbor Intl
Tue 6/30
10:32 pm-7:23 pm
2 stops18h 51m
$169
Showing 1-10 of 21 resultsSorted by cheapest first
Best time to book a flight from Mesa to St. Louis
Have a flexible travel schedule? Discover the best time to fly to St. Louis from Mesa with our price prediction graph.
PHX-STL
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mesa to St. Louis
MS9-STL
PHX-STL
What is the cheapest time of day to fly from MS9 to STL?
Find hourly flight availability from Mesa to St. Louis. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 4, 2026.
A simple way to save on the total cost of your ticket is to fly from Mesa to St. Louis at noon. If you’re flexible enough to do this you can expect to save up to 17% on your trip compared to booking a flight in the evening.
How much does it cost to fly round-trip from Mesa to St. Louis?
What is the cheapest day to fly from Mesa to St. Louis?
Use this chart to determine the cheapest time to fly round-trip from Mesa to St. Louis. Price data was last updated on May 30, 2026.
Travelers seeking maximum savings on their Mesa to St. Louis flight should consider departing on Friday afternoons when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing St. Louis
Get insights into the airlines that provide service to St. Louis. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to St. Louis. Reviews last updated June 4, 2026.
Read reviews from past customers who have flown Southwest,American Airlines, andFrontier from Mesa to St. Louis. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Boarding
8.1
Entertainment
7.5
Crew
8.6
Food
7.0
Comfort
8.0
Overall
8.0
Reviews
1 / 20
10.0
ExcellentWalter,May 2026
LAS - BUR
Related info for your journey
Find useful and relevant information for your journey from Mesa to St. Louis. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near St. Louis?
Book flights to St. Louis if you plan to visit one of these locationsO'Fallon
Edwardsville
Fenton
Swansea
Fairview Heights
Maryland Heights
Collinsville
Eureka
Wentzville
Glencoe
Chesterfield
Alton
Farmington
Festus
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Mesa and St. Louis flights
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Mesa to St. Louis flights
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Top 3 airlines flying from Mesa to St. Louis
Discover the top 3 airlines that operate flights from Mesa to St. Louis. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 4, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$99 | Average$208 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$229 | Average$386 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$259 | Average$407 | FlexibilityNo cancel fee | On-time63% |