$106+ Cheap flights from St. Louis (STL) to Mesa, AZ
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
STL — PHX
Aug 23 — Aug 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from St. Louis to Mesa with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Lambert-St Louis to Mesa are usually found in November or December, booked 24 days in advance, depart on a Wednesday or Friday and return on a Friday
Cheap flight deals from St. Louis to Mesa
Cheapest
Best
Last-minute
One-way
Cheapest flights from St. Louis to MesaExplore the most affordable flight options available from St. Louis to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
Explore the most affordable flight options available from St. Louis to Mesa. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/118:10 pm
STL
- PHX
1 stop17h 32m
Frontier
Mon 9/149:06 am
PHX
- STL
1 stop8h 09m
Frontier
Deal found 7/22![Frontier logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/288:10 pm
STL
- PHX
1 stop13h 48m
Frontier
Wed 10/73:21 pm
PHX
- STL
1 stop25h 54m
Frontier
Deal found 7/23![Frontier logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:08 pm
STL
- PHX
1 stop16h 03m
Frontier
Wed 8/194:48 pm
PHX
- STL
1 stop24h 25m
Frontier
Deal found 7/22![Frontier logo]()
$211
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/154:57 pm
STL
- PHX
1 stop7h 19m
Frontier
Thu 8/206:35 am
PHX
- STL
1 stop10h 38m
Frontier
Deal found 7/22![Frontier logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
STL
- PHX
1 stop13h 04m
Frontier
Sat 10/108:16 am
PHX
- STL
1 stop8h 59m
Frontier
Deal found 7/22![Frontier logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
STL
- PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
- STL
1 stop11h 10m
Frontier
Deal found 7/22![Frontier logo]()
$218
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/110:35 am
STL
- PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
- STL
1 stop11h 10m
Frontier
Deal found 7/22![Frontier logo]()
$221
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/205:27 pm
STL
- PHX
1 stop7h 33m
Frontier
Thu 8/278:35 am
PHX
- STL
1 stop8h 38m
Frontier
Deal found 7/23![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/510:35 am
STL
- PHX
1 stop13h 04m
Frontier
Thu 10/86:05 am
PHX
- STL
1 stop11h 10m
Frontier
Deal found 7/22![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/148:10 pm
STL
- PHX
1 stop13h 48m
Frontier
Fri 9/184:44 pm
PHX
- STL
2 stops38h 56m
Frontier
Deal found 7/23![Frontier logo]()
$228
Best flights from St. Louis to MesaDiscover carefully curated flight deals from St. Louis to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
Discover carefully curated flight deals from St. Louis to Mesa that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 24, 2026.
This Alaska Airlines deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/36:02 am
STL
- PHX
2 stops14h 40m
Alaska Airlines
Wed 10/77:38 am
PHX
- STL
2 stops14h 21m
Alaska Airlines
Deal found 7/20![Alaska Airlines logo]()
$334
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/176:25 am
STL
- PHX
Nonstop3h 20m
Southwest
Sat 10/176:45 pm
PHX
- STL
Nonstop2h 50m
Southwest
Deal found 7/23![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/1911:55 am
STL
- PHX
Nonstop3h 10m
Southwest
Wed 8/266:00 am
PHX
- STL
Nonstop2h 55m
Southwest
Deal found 7/22![Southwest logo]()
$353
This Southwest deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/15:05 am
STL
- PHX
Nonstop3h 25m
Southwest
Mon 10/58:25 pm
PHX
- STL
Nonstop2h 50m
Southwest
Deal found 7/22![Southwest logo]()
$353
This Alaska Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:02 am
STL
- PHX
2 stops16h 39m
Alaska Airlines
Mon 11/211:20 am
PHX
- STL
2 stops11h 36m
Alaska Airlines
Deal found 7/23![Alaska Airlines logo]()
$404
This Southwest deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1011:50 am
STL
- PHX
Nonstop3h 10m
Southwest
Mon 9/215:00 am
PHX
- STL
1 stop6h 05m
Southwest
Deal found 7/21![Southwest logo]()
$363
This Alaska Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/47:02 am
STL
- PHX
1 stop14h 49m
Alaska Airlines
Wed 10/77:38 am
PHX
- STL
2 stops14h 21m
Alaska Airlines
Deal found 7/23![Alaska Airlines logo]()
$458
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:25 am
STL
- PHX
Nonstop3h 15m
Southwest
Thu 9/173:25 pm
PHX
- STL
Nonstop2h 55m
Southwest
Deal found 7/20![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:25 am
STL
- PHX
Nonstop3h 25m
Southwest
Sat 10/106:45 pm
PHX
- STL
Nonstop2h 50m
Southwest
Deal found 7/19![Southwest logo]()
$393
This Southwest deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/208:30 am
STL
- PHX
1 stop6h 05m
Southwest
Thu 11/265:35 am
PHX
- STL
2 stops7h 10m
Southwest
Deal found 7/23![Southwest logo]()
$430
This Southwest deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am
STL
- PHX
1 stop6h 30m
Southwest
Fri 10/25:10 am
PHX
- STL
Nonstop2h 50m
Southwest
Deal found 7/20![Southwest logo]()
$434
This Southwest deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/96:15 am
STL
- PHX
Nonstop3h 15m
Southwest
Wed 8/123:25 pm
PHX
- STL
Nonstop2h 55m
Southwest
Deal found 7/19![Southwest logo]()
$456
Last-minute flights from St. Louis to MesaDiscover last-minute flight deals from St. Louis to Mesa. Data last updated July 24, 2026 and is based on user searches.
Discover last-minute flight deals from St. Louis to Mesa. Data last updated July 24, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/297:03 pm
STL
- PHX
1 stop6h 02m
Frontier
Mon 8/38:40 am
PHX
- STL
1 stop8h 43m
Frontier
Deal found 7/21![Frontier logo]()
$354
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:08 pm
STL
- PHX
1 stop5h 24m
Frontier
Mon 8/246:35 am
PHX
- STL
1 stop10h 38m
Frontier
Deal found 7/20![Frontier logo]()
$323
This FlightHub deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure FlightHub is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Wed 8/511:17 am
PHX
- STL
1 stop6h 06m
Frontier
Deal found 7/23![Frontier logo]()
$357
This Frontier deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/308:08 pm
STL
- PHX
1 stop5h 24m
Frontier
Sun 8/26:24 am
PHX
- STL
1 stop6h 32m
Frontier
Deal found 7/19![Frontier logo]()
$372
This Expedia deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Mon 8/39:58 pm
PHX
- STL
1 stop18h 07m
Frontier
Deal found 7/23![Frontier logo]()
$382
This Expedia deal was found by Cheapflights users on 7/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/17:10 pm
STL
- PHX
1 stop5h 55m
Frontier
Sat 8/89:58 pm
PHX
- STL
1 stop18h 17m
Frontier
Deal found 7/20![Frontier logo]()
$336
This Frontier deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:41 pm
STL
- PHX
1 stop9h 18m
Frontier
Tue 8/411:19 am
PHX
- STL
1 stop6h 04m
Frontier
Deal found 7/24![Frontier logo]()
$342
This Kiwi.com deal was found by Cheapflights users on 7/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/24:09 pm
STL
- PHX
2 stops17h 31m
Frontier
Mon 8/36:53 pm
PHX
- STL
1 stop22h 30m
Frontier
Deal found 7/19![Frontier logo]()
$421
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:08 pm
STL
- PHX
1 stop16h 03m
Frontier
Thu 8/66:53 pm
PHX
- STL
1 stop22h 30m
Frontier
Deal found 7/23![Frontier logo]()
$369
One-way flights from St. Louis to MesaSearch for one-way flight options from St. Louis to Mesa. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
Search for one-way flight options from St. Louis to Mesa. Find affordable one-way fares based on user searches. Data last updated July 24, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:08 pm
STL
- PHX
1 stop13h 32m
Frontier
Deal found 7/23![Frontier logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/247:58 pm
STL
- PHX
1 stop19h 19m
Frontier
Deal found 7/22![Frontier logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/208:10 pm
STL
- PHX
1 stop20h 25m
Frontier
Deal found 7/22![Frontier logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/310:35 am
STL
- PHX
1 stop13h 04m
Frontier
Deal found 7/22![Frontier logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/108:10 pm
STL
- PHX
1 stop17h 32m
Frontier
Deal found 7/21![Frontier logo]()
$114
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/2210:35 am
STL
- PHX
2 stops38h 09m
Frontier
Deal found 7/23![Frontier logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1210:35 am
STL
- PHX
2 stops14h 40m
Frontier
Deal found 7/23![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:17 pm
STL
- PHX
1 stop18h 57m
Frontier
Deal found 7/22![Frontier logo]()
$119
This Kiwi.com deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/216:17 pm
STL
- PHX
2 stops20h 25m
Frontier
Deal found 7/22![Frontier logo]()
$121
This Priceline deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/206:45 pm
STL
- PHX
1 stop6h 39m
Frontier
Deal found 7/22![Frontier logo]()
$122
Find flight deals from St. Louis to Mesa
Keep the following information in mind while searching for St. Louis to Mesa flight deals. Data was last updated July 24, 2026.
Round-trip from | $209 (Kiwi.com) |
|---|---|
One-way from | $106 (Kiwi.com) |
Popular in | June |
Cheapest in | November |
Average price | $396 |
Cheapflights Fare Finder
Customize your flight search to find flights from St. Louis to Mesa that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
Use the filters below to find and compare flights from St. Louis to Mesa that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Sat 10/3
6:02 am-6:42 pm
2 stops14h 40m
Phoenix Sky Harbor Intl
Wed 10/7
7:38 am-11:59 pm
2 stops14h 21m
$334
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Sat 10/17
6:25 am-7:45 am
Nonstop3h 20m
Phoenix Sky Harbor Intl
Sat 10/17
6:45 pm-11:35 pm
Nonstop2h 50m
$353
Quickest round-trip
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Wed 8/19
11:55 am-1:05 pm
Nonstop3h 10m
Phoenix Sky Harbor Intl
Wed 8/26
6:00 am-10:55 am
Nonstop2h 55m
$353
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Thu 10/1
5:05 am-6:30 am
Nonstop3h 25m
Phoenix Sky Harbor Intl
Mon 10/5
8:25 pm-1:15 am
Nonstop2h 50m
$353
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Thu 9/10
11:50 am-1:00 pm
Nonstop3h 10m
Phoenix Sky Harbor Intl
Mon 9/21
5:00 am-1:05 pm
1 stop6h 05m
$363
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Sat 9/12
8:25 am-9:40 am
Nonstop3h 15m
Phoenix Sky Harbor Intl
Thu 9/17
3:25 pm-8:20 pm
Nonstop2h 55m
$393
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Sat 10/3
8:25 am-9:50 am
Nonstop3h 25m
Phoenix Sky Harbor Intl
Sat 10/10
6:45 pm-11:35 pm
Nonstop2h 50m
$393
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Sat 10/31
6:02 am-8:41 pm
2 stops16h 39m
Phoenix Sky Harbor Intl
Mon 11/2
11:20 am-11:56 pm
2 stops11h 36m
$404
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Fri 11/20
8:30 am-1:35 pm
1 stop6h 05m
Phoenix Sky Harbor Intl
Thu 11/26
5:35 am-1:45 pm
2 stops7h 10m
$430
St. LouisPhoenix
STL - PHX
STLPHX
Lambert-St Louis
Wed 9/30
6:00 am-10:30 am
1 stop6h 30m
Phoenix Sky Harbor Intl
Fri 10/2
5:10 am-10:00 am
Nonstop2h 50m
$434
Showing 1-10 of 23 resultsSorted by cheapest first
Best time to book a flight from St. Louis to Mesa
Have a flexible travel schedule? Discover the best time to fly to Mesa from St. Louis with our price prediction graph.
STL-PHX
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from St. Louis to Mesa
STL-MS9
STL-PHX
What is the cheapest time of day to fly from STL to MS9?
Find hourly flight availability from St. Louis to Mesa. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 24, 2026.
It’s optimal to fly from St. Louis to Mesa in the evening. By choosing this option you can save up to 30% on the cost of your flight, compared to a flight in the morning.
Weekly flight availability from St. Louis to Mesa
Explore weekly flight availability from St. Louis to Mesa. Discover flights operating on different days of the week, giving you the flexibility to choose a travel day that best fits your plans. Compare info to find the most convenient option for your journey. Data last updated July 24, 2026.
The most flights from STL to MS9 are scheduled on a Thursday (9 on average). You will have fewer flight options on Saturday, which is when the least amount of flights are scheduled (4 on average).
How much does it cost to fly round-trip from St. Louis to Mesa?
Airfare is below average for this route at the moment.
St. Louis to Mesa flights typically cost between $328 and $426 in September.The cheapest round-trip price found within the last 5 days was $209 on Frontier (Sep 11-Sep 14).
What is the cheapest day to fly from St. Louis to Mesa?
Use this chart to determine the cheapest time to fly round-trip from St. Louis to Mesa. Price data was last updated on July 18, 2026.
Travelers seeking maximum savings on their St. Louis to Mesa flight should consider departing on Friday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.
Reviews of airlines servicing Mesa
Get insights into the airlines that provide service to Mesa. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Mesa. Reviews last updated July 24, 2026.
Read through reviews of airlines operating flights from St. Louis to Mesa, such as Southwest,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
2.0
MediocreBhoopal,Nov 2024
STL - BOS
Related info for your journey
Find useful and relevant information for your journey from St. Louis to Mesa. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from St. Louis
Popular flights
Top destinations
Alternative routes for St. Louis to Mesa
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Mesa by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from St. Louis to Mesa by cabin class
Find flights from St. Louis to Mesa, based on your preferred cabin class, be it economy, premium economy, business, or first class.
St. Louis and Mesa flights
Browse other St. Louis and Mesa flight options. Last updated on July 24, 2026.
Other flights from St. Louis
Browse through other flights departing from St. Louis. Flights are based on user searches made on Cheapflights and were last updated on July 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
St. Louis to Mesa flights
Consider these flights traveling from St. Louis to Mesa.
Top 5 airlines flying from St. Louis to Mesa
Discover the top 5 airlines that operate flights from St. Louis to Mesa. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$94 | Average$211 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$148 | Average$381 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$216 | Average$381 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$233 | Average$402 | FlexibilityNo cancel fee | On-time63% | |
| Cheapest$292 | Average$380 | FlexibilityNo cancel fee | On-time62% |