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La Crosse

$401+ Cheap flights from North Carolina to La Crosse (LSE)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/31. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — LSE
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from North Carolina to La Crosse

Cheapest flights from North Carolina to La Crosse
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/206:00 pmCLT - LSE
1 stop6h 43mAmerican Airlines
Sat 12/2710:12 amLSE - CLT
1 stop5h 44mAmerican Airlines
Deal found 12/16$677
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/202:52 pmCLT - LSE
1 stop5h 44mAmerican Airlines
Sun 12/286:00 amLSE - CLT
1 stop6h 26mAmerican Airlines
Deal found 12/17$684
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 pmCLT - LSE
1 stop6h 43mAmerican Airlines
Sat 12/2710:12 amLSE - CLT
1 stop5h 44mAmerican Airlines
Deal found 12/17$685
This American Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/216:00 pmCLT - LSE
1 stop6h 43mAmerican Airlines
Sun 12/286:00 amLSE - CLT
1 stop6h 26mAmerican Airlines
Deal found 12/17$692

Find flight deals from North Carolina to La Crosse

Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated December 18, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$464
(American Airlines)

One-way from

$401
(American Airlines)
Provider with most accurate pricing for Raleigh-Durham-La Crosse flight deals.
Search Deals
Provider most trusted by Cheapflights users for Raleigh-Durham-La Crosse flights.
Search Deals
From North Carolina to La Crosse
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One-way flight from North Carolina to La Crosse
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Cheapflights Fare Finder

 
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.

Fly from

North Carolina

Fly to

La Crosse

Route

Depart

Return

Price

RaleighLa Crosse

RDU - LSE

RDULSE

Raleigh-Durham

Fri 1/16

6:30 pm-10:16 pm

1 stop4h 46m

La Crosse

Sun 1/18

5:08 pm-11:59 pm

1 stop5h 51m

$464

RaleighLa Crosse

RDU - LSE

RDULSE

Raleigh-Durham

Fri 1/16

7:58 am-4:16 pm

2 stops9h 18m

La Crosse

Mon 1/19

5:08 pm-11:59 pm

1 stop5h 51m

$470

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Mon 12/22

6:00 pm-11:43 pm

1 stop6h 43m

La Crosse

Sat 12/27

10:12 am-4:56 pm

1 stop5h 44m

$685

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Sun 12/21

6:00 pm-11:43 pm

1 stop6h 43m

La Crosse

Sat 12/27

10:12 am-4:56 pm

1 stop5h 44m

$685

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Mon 12/22

6:00 pm-11:43 pm

1 stop6h 43m

La Crosse

Sun 12/28

6:00 am-1:26 pm

1 stop6h 26m

$692

CharlotteLa Crosse

CLT - LSE

CLTLSE

Charlotte Douglas

Sun 12/21

6:00 pm-11:43 pm

1 stop6h 43m

La Crosse

Sun 12/28

6:00 am-1:26 pm

1 stop6h 26m

$692

NorfolkLa Crosse

ORF - LSE

ORFLSE

Norfolk

Thu 1/1

3:18 pm-7:36 pm

1 stop5h 18m

$465

NorfolkLa Crosse

ORF - LSE

ORFLSE

Norfolk

Sun 1/4

2:44 pm-11:38 pm

2 stops9h 54m

$506

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Best time to book a flight from North Carolina to La Crosse

Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from North Carolina to La Crosse

What is the cheapest month to book a flight from North Carolina to La Crosse?

Currently, January is the cheapest month in which you can book a flight from North Carolina to La Crosse (average of $248). Flying from North Carolina to La Crosse in February is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Related info for your journey

Find useful and relevant information for your journey from North Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to La Crosse from North Carolina?

    La Crosse (LSE) is the airport you will fly into if you book a flight from North Carolina to La Crosse. It is only a 5.4 mi journey from La Crosse (LSE) to La Crosse’s city center.

  • How long is the flight from North Carolina to La Crosse?

    There are many flights that can get you from North Carolina to La Crosse in 4h 46m. Fly via American Airlines to get the fastest option. North Carolina and La Crosse are separated by a distance of 859 mi.

  • What are the most popular routes from North Carolina to La Crosse?

    The most popular flight routes from North Carolina to La Crosse are Knoxville McGhee Tyson - La Crosse, Raleigh-Durham - La Crosse and Charlotte Douglas - La Crosse.

  • Can I find deals for flights from North Carolina to La Crosse that include hotel bookings?

    Yes. In addition to deals on North Carolina to La Crosse flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from North Carolina to La Crosse?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from North Carolina to La Crosse.

  • Can I find deals for business class flights from North Carolina to La Crosse?

    Yes. Cheapflights offers flight deals from North Carolina to La Crosse by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from North Carolina to La Crosse?

    Currently, January is the cheapest month in which you can book a flight from North Carolina to La Crosse (average of $248). Flying from North Carolina to La Crosse in February is currently the most expensive (average of $607). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near La Crosse?

Book flights to La Crosse if you plan to visit one of these locations
Winona
Decorah

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Alternative routes for North Carolina to La Crosse

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Top airline flying from North Carolina to La Crosse

Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$400Average$492FlexibilityNo cancel feeOn-time71%

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