$410+ Cheap flights from North Carolina to La Crosse (LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/20. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — LSE
Aug 27 — Sep 31
1 adult, Economy
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1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to La Crosse
Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated August 22, 2025.
Round-trip from | $410 (American Airlines) |
|---|
Find flight deals from North Carolina to La Crosse
Cheapest flights from North Carolina to La CrosseExplore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 22, 2025.
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/203:36 pmRDU - LSE
1 stop7h 28mAmerican Airlines
Sat 9/276:30 pmLSE - RDU
1 stop4h 24mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$410
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/174:17 pmCLT - LSE
1 stop6h 47mAmerican Airlines
Wed 10/16:00 amLSE - CLT
1 stop4h 43mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$425
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/138:17 pmGSO - LSE
1 stop4h 09mAmerican Airlines
Thu 10/2310:54 amLSE - GSO
2 stops11h 45mAmerican Airlines
Deal found 8/20![American Airlines logo]()
$470
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/66:25 pmRDU - LSE
1 stop4h 20mAmerican Airlines
Tue 12/92:48 pmLSE - RDU
1 stop5h 58mAmerican Airlines
Deal found 8/20![American Airlines logo]()
$480
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/71:01 pmTYS - LSE
1 stop5h 44mAmerican Airlines
Tue 10/1410:54 amLSE - TYS
2 stops10h 15mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 8/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/64:30 pmCLT - LSE
1 stop6h 15mAmerican Airlines
Tue 12/92:48 pmLSE - CLT
1 stop6h 01mAmerican Airlines
Deal found 8/20![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/186:00 pmCLT - LSE
1 stop6h 17mAmerican Airlines
Thu 9/256:00 amLSE - CLT
1 stop5h 29mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$501
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/93:03 pmTYS - LSE
1 stop3h 42mAmerican Airlines
Tue 10/1410:54 amLSE - TYS
2 stops10h 15mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$513
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:03 pmTYS - LSE
1 stop3h 42mAmerican Airlines
Sun 10/126:00 amLSE - TYS
1 stop5h 31mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/226:10 amGSO - LSE
1 stop5h 13mAmerican Airlines
Mon 8/2510:53 amLSE - GSO
2 stops6h 23mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/65:37 pmTYS - LSE
1 stop6h 49mAmerican Airlines
Tue 10/1410:54 amLSE - TYS
2 stops10h 15mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$520
This American Airlines deal was found by Cheapflights users on 8/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/73:03 pmTYS - LSE
1 stop3h 42mAmerican Airlines
Wed 10/1510:54 amLSE - TYS
1 stop4h 43mAmerican Airlines
Deal found 8/21![American Airlines logo]()
$527
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.
Fly from
North Carolina
Fly to
La Crosse
Route
Depart
Return
Price
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sat 9/20
3:36 pm-10:04 pm
1 stop7h 28m
La Crosse
Sat 9/27
6:30 pm-11:54 pm
1 stop4h 24m
$410
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Wed 9/17
4:17 pm-10:04 pm
1 stop6h 47m
La Crosse
Wed 10/1
6:00 am-11:43 am
1 stop4h 43m
$425
GreensboroLa Crosse
GSO - LSE
GSOLSE
Greensboro/H. Point
Mon 10/13
8:17 pm-11:26 pm
1 stop4h 09m
La Crosse
Thu 10/23
10:54 am-11:39 pm
2 stops11h 45m
$470
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sat 12/6
4:28 pm-9:45 pm
1 stop6h 17m
La Crosse
Tue 12/9
2:48 pm-9:46 pm
1 stop5h 58m
$480
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Tue 10/7
1:01 pm-5:45 pm
1 stop5h 44m
La Crosse
Tue 10/14
10:54 am-10:09 pm
2 stops10h 15m
$486
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Sat 10/11
5:35 pm-11:26 pm
1 stop6h 51m
La Crosse
Tue 10/14
10:54 am-10:09 pm
2 stops10h 15m
$486
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Wed 10/8
3:03 pm-5:45 pm
1 stop3h 42m
La Crosse
Tue 10/14
10:54 am-10:09 pm
2 stops10h 15m
$486
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Sat 12/6
11:15 am-2:21 pm
1 stop4h 06m
La Crosse
Tue 12/9
2:48 pm-9:49 pm
1 stop6h 01m
$488
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Thu 9/18
6:00 pm-11:17 pm
1 stop6h 17m
La Crosse
Thu 9/25
6:00 am-12:29 pm
1 stop5h 29m
$501
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Thu 10/9
3:03 pm-5:45 pm
1 stop3h 42m
La Crosse
Tue 10/14
10:54 am-10:09 pm
2 stops10h 15m
$513
Showing 1-10 of 14 results
Best time to book a flight from North Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to La Crosse
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Related info for your journey
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Alternative routes for North Carolina to La Crosse
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Top airline flying from North Carolina to La Crosse
Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 22, 2025.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$410 | Average$504 | FlexibilityNo cancel fee | On-time71% |