$273+ Cheap flights from North Carolina to La Crosse (LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/14. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — LSE
Apr 21 — Apr 281
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to La Crosse with Cheapflights
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from North Carolina to La CrosseExplore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Sat 5/235:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 3/17![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:05 pm
CLT
- LSE
1 stop6h 02m
American Airlines
Fri 4/2410:05 am
LSE
- CLT
1 stop7h 36m
American Airlines
Deal found 3/18![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Mon 6/225:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 3/21![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:13 am
RDU
- LSE
1 stop17h 41m
American Airlines
Sun 4/126:37 pm
LSE
- RDU
1 stop15h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:45 am
RDU
- LSE
1 stop13h 22m
American Airlines
Mon 5/46:37 pm
LSE
- RDU
1 stop15h 34m
American Airlines
Deal found 3/17![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/237:44 am
RDU
- LSE
1 stop11h 05m
American Airlines
Mon 9/286:24 pm
LSE
- RDU
1 stop15h 50m
American Airlines
Deal found 3/20![American Airlines logo]()
$534
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:28 pm
RDU
- LSE
2 stops8h 38m
American Airlines
Sun 5/246:00 am
LSE
- RDU
1 stop4h 29m
American Airlines
Deal found 3/19![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:15 pm
GSO
- LSE
1 stop4h 21m
American Airlines
Wed 4/85:40 am
LSE
- GSO
1 stop4h 29m
American Airlines
Deal found 3/20![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:28 pm
RDU
- LSE
2 stops8h 38m
American Airlines
Mon 5/256:00 am
LSE
- RDU
2 stops5h 50m
American Airlines
Deal found 3/19![American Airlines logo]()
$555
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/234:32 pm
RDU
- LSE
1 stop7h 43m
American Airlines
Sun 9/276:24 pm
LSE
- RDU
1 stop4h 03m
American Airlines
Deal found 3/20![American Airlines logo]()
$564
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:43 pm
ORF
- LSE
1 stop4h 53m
American Airlines
Tue 4/75:40 am
LSE
- ORF
2 stops7h 27m
American Airlines
Deal found 3/19![American Airlines logo]()
$587
This United Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/110:40 am
CLT
- LSE
1 stop23h 16m
United Airlines
Sat 12/59:42 am
LSE
- CLT
1 stop14h 08m
United Airlines
Deal found 3/17![United Airlines logo]()
$606
Best flights from North Carolina to La CrosseDiscover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
Discover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Sat 5/165:40 am
LSE
- CLT
1 stop5h 10m
American Airlines
Deal found 3/19![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Sat 5/235:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 3/17![American Airlines logo]()
$318
This United Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:30 am
GSO
- LSE
1 stop12h 40m
United Airlines
Wed 9/168:15 am
LSE
- GSO
1 stop24h 10m
United Airlines
Deal found 3/20![United Airlines logo]()
$646
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/176:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Fri 4/2410:05 am
LSE
- CLT
1 stop7h 36m
American Airlines
Deal found 3/18![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/91:09 pm
RDU
- LSE
2 stops11h 45m
American Airlines
Sun 4/126:37 pm
LSE
- RDU
1 stop15h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$466
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/15:45 am
RDU
- LSE
1 stop13h 22m
American Airlines
Mon 5/46:37 pm
LSE
- RDU
1 stop15h 34m
American Airlines
Deal found 3/17![American Airlines logo]()
$484
This United Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/1810:27 am
CLT
- LSE
2 stops13h 10m
United Airlines
Mon 6/227:11 pm
LSE
- CLT
2 stops13h 34m
United Airlines
Deal found 3/21![United Airlines logo]()
$764
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:28 pm
RDU
- LSE
2 stops8h 38m
American Airlines
Mon 5/256:00 am
LSE
- RDU
1 stop5h 19m
American Airlines
Deal found 3/19![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:15 pm
GSO
- LSE
1 stop4h 21m
American Airlines
Wed 4/85:40 am
LSE
- GSO
1 stop4h 29m
American Airlines
Deal found 3/20![American Airlines logo]()
$550
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/224:28 pm
RDU
- LSE
2 stops8h 38m
American Airlines
Sun 5/246:00 am
LSE
- RDU
2 stops8h 18m
American Airlines
Deal found 3/19![American Airlines logo]()
$555
This KAYAK deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:24 pm
RDU
- LSE
1 stop6h 12m
American Airlines
Wed 4/85:40 am
LSE
- RDU
1 stop4h 31m
American Airlines
Deal found 3/19![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 3/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Mon 6/226:00 am
LSE
- CLT
2 stops6h 26m
American Airlines
Deal found 3/21![American Airlines logo]()
$639
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/31:43 pm
ORF
- LSE
2 stops10h 53m
American Airlines
Tue 4/75:40 am
LSE
- ORF
2 stops8h 51m
American Airlines
Deal found 3/19![American Airlines logo]()
$684
This American Airlines deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/1611:10 am
CLT
- LSE
2 stops7h 57m
American Airlines
Mon 4/205:40 am
LSE
- CLT
1 stop5h 10m
American Airlines
Deal found 3/22![American Airlines logo]()
$763
Last-minute flights from North Carolina to La CrosseDiscover last-minute flight deals from North Carolina to La Crosse. Data last updated March 22, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to La Crosse. Data last updated March 22, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/37:43 pm
ORF
- LSE
1 stop4h 53m
American Airlines
Tue 4/75:40 am
LSE
- ORF
2 stops7h 27m
American Airlines
Deal found 3/19![American Airlines logo]()
$587
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/48:15 pm
GSO
- LSE
1 stop4h 21m
American Airlines
Wed 4/85:40 am
LSE
- GSO
1 stop4h 29m
American Airlines
Deal found 3/20![American Airlines logo]()
$550
This KAYAK deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure KAYAK is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:24 pm
RDU
- LSE
1 stop6h 12m
American Airlines
Wed 4/85:40 am
LSE
- RDU
1 stop4h 31m
American Airlines
Deal found 3/19![American Airlines logo]()
$634
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/97:13 am
RDU
- LSE
1 stop17h 41m
American Airlines
Sun 4/126:37 pm
LSE
- RDU
1 stop15h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$460
This American Airlines deal was found by Cheapflights users on 3/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Sat 5/235:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 3/17![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 3/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/171:05 pm
CLT
- LSE
1 stop6h 02m
American Airlines
Fri 4/2410:05 am
LSE
- CLT
1 stop7h 36m
American Airlines
Deal found 3/18![American Airlines logo]()
$426
One-way flights from North Carolina to La CrosseSearch for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
Search for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated March 22, 2026.
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:05 pm
CLT
- LSE
1 stop6h 02m
American Airlines
Deal found 3/19![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/256:26 pm
CLT
- LSE
1 stop6h 10m
American Airlines
Deal found 3/20![American Airlines logo]()
$339
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/2712:21 pm
TYS
- LSE
2 stops12h 15m
American Airlines
Deal found 3/19![American Airlines logo]()
$346
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/288:00 am
TYS
- LSE
3 stops52h 53m
Allegiant Air
Deal found 3/19![Allegiant Air logo]()
$379
This United Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/146:00 am
CLT
- LSE
2 stops19h 17m
United Airlines
Deal found 3/19![United Airlines logo]()
$400
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 3/287:40 am
TYS
- LSE
1 stop4h 22m
American Airlines
Deal found 3/19![American Airlines logo]()
$413
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/18:30 am
TYS
- LSE
3 stops52h 23m
Multiple Airlines
Deal found 3/19![Multiple Airlines logo]()
$449
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/19:25 am
TYS
- LSE
2 stops9h 34m
American Airlines
Deal found 3/19![American Airlines logo]()
$452
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/2912:53 pm
TYS
- LSE
1 stop24h 00m
Allegiant Air
Deal found 3/19![Allegiant Air logo]()
$469
This Kiwi.com deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:00 am
TYS
- LSE
1 stop28h 53m
Allegiant Air
Deal found 3/19![Allegiant Air logo]()
$517
This Kiwi.com deal was found by Cheapflights users on 3/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/257:00 am
CLT
- LSE
3 stops53h 53m
Multiple Airlines
Deal found 3/20![Multiple Airlines logo]()
$562
This American Airlines deal was found by Cheapflights users on 3/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/314:02 pm
TYS
- LSE
1 stop19h 59m
American Airlines
Deal found 3/19![American Airlines logo]()
$628
Find flight deals from North Carolina to La Crosse
Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated March 22, 2026.
Round-trip from | $318 (American Airlines) |
|---|---|
One-way from | $273 (American Airlines) |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Thu 5/14
6:00 pm-11:54 pm
1 stop6h 54m
La Crosse
Sat 5/16
5:40 am-11:50 am
1 stop5h 10m
$318
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Sat 4/11
6:00 pm-11:54 pm
1 stop6h 54m
La Crosse
Sat 5/23
5:34 pm-11:59 pm
1 stop5h 25m
$318
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Fri 4/17
6:00 pm-11:54 pm
1 stop6h 54m
La Crosse
Fri 4/24
10:05 am-6:41 pm
1 stop7h 36m
$318
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Thu 4/9
1:09 pm-11:54 pm
2 stops11h 45m
La Crosse
Sun 4/12
6:37 pm-11:11 am
1 stop15h 34m
$466
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Fri 5/1
5:45 am-6:07 pm
1 stop13h 22m
La Crosse
Mon 5/4
6:37 pm-11:11 am
1 stop15h 34m
$484
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Fri 5/22
4:28 pm-12:06 am
2 stops8h 38m
La Crosse
Mon 5/25
6:00 am-12:19 pm
1 stop5h 19m
$550
Quickest round-trip
GreensboroLa Crosse
GSO - LSE
GSOLSE
Greensboro/H. Point
Sat 4/4
8:15 pm-11:36 pm
1 stop4h 21m
La Crosse
Wed 4/8
5:40 am-11:09 am
1 stop4h 29m
$550
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Fri 5/22
4:28 pm-12:06 am
2 stops8h 38m
La Crosse
Sun 5/24
6:00 am-3:18 pm
2 stops8h 18m
$555
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Mon 4/6
6:24 pm-11:36 pm
1 stop6h 12m
La Crosse
Wed 4/8
5:40 am-11:11 am
1 stop4h 31m
$634
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Thu 6/18
8:10 pm-12:06 am
1 stop4h 56m
La Crosse
Mon 6/22
6:00 am-1:26 pm
2 stops6h 26m
$639
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Best time to book a flight from North Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
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Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to La Crosse
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What is the cheapest month to book a flight from North Carolina to La Crosse?
Currently, May is the cheapest month in which you can book a flight from North Carolina to La Crosse (average of $253). Flying from North Carolina to La Crosse in March is currently the most expensive (average of $966). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Alternative routes for North Carolina to La Crosse
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Complete your trip
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Other flights to La Crosse
Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 22, 2026.
North Carolina and La Crosse flights
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North Carolina to La Crosse flights
Consider these flights traveling from North Carolina to La Crosse.
Top airline flying from North Carolina to La Crosse
Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$469 | Average$534 | FlexibilityNo cancel fee | On-time71% |