$300+ Cheap flights from North Carolina to La Crosse (LSE)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/21. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — LSE
Oct 30 — Nov 61
Round-trip
1 adult, Economy
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Find cheap flights from North Carolina to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from North Carolina to La CrosseExplore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:50 am -
1 stop7h 06m
Tue 11/246:50 pm -
1 stop4h 41m
Deal found 9/30![American Airlines logo]()
$300
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:42 pm -
1 stop12h 24m
Sun 10/1811:41 am -
1 stop19h 56m
Deal found 9/29![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:28 pm -
1 stop6h 31m
Sat 10/176:58 am -
1 stop7h 16m
Deal found 9/28![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:25 pm -
1 stop4h 34m
Sat 10/176:58 am -
1 stop6h 59m
Deal found 9/28![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/48:15 pm -
1 stop5h 03m
Sun 12/612:24 pm -
2 stops7h 02m
Deal found 9/25![American Airlines logo]()
$456
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:31 am -
1 stop5h 25m
Sat 11/286:50 pm -
1 stop4h 21m
Deal found 9/26![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:00 am -
1 stop6h 22m
Tue 10/67:00 am -
1 stop6h 57m
Deal found 9/27![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/296:15 pm -
2 stops7h 05m
Wed 10/77:04 am -
1 stop5h 14m
Deal found 9/27![American Airlines logo]()
$488
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected ” under the list of providers to see comparable flight deals.
Thu 10/157:49 am -
1 stop5h 04m
Mon 10/197:04 am -
1 stop7h 10m
Deal found 9/30![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:33 pm -
1 stop6h 47m
Sun 11/296:01 am -
1 stop5h 04m
Deal found 9/27![American Airlines logo]()
$575
Best flights from North Carolina to La CrosseDiscover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
Discover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 30, 2026.
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/215:00 am -
2 stops7h 56m
Tue 11/246:50 pm -
1 stop4h 41m
Deal found 9/28![American Airlines logo]()
$306
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:42 pm -
1 stop12h 24m
Sun 10/1811:41 am -
1 stop19h 56m
Deal found 9/29![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:28 pm -
1 stop6h 31m
Sat 10/176:58 am -
1 stop7h 16m
Deal found 9/28![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/133:42 pm -
2 stops9h 17m
Sat 10/176:58 am -
1 stop6h 59m
Deal found 9/28![American Airlines logo]()
$378
This American Airlines deal was found by Cheapflights users on 9/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/257:31 am -
1 stop5h 25m
Sat 11/286:50 pm -
1 stop4h 21m
Deal found 9/26![American Airlines logo]()
$457
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/410:21 am -
2 stops8h 55m
Sun 12/612:24 pm -
2 stops8h 42m
Deal found 9/25![American Airlines logo]()
$461
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:49 am -
1 stop5h 04m
Mon 10/197:04 am -
1 stop7h 10m
Deal found 9/30![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/156:00 am -
1 stop6h 53m
Mon 10/197:04 am -
1 stop6h 53m
Deal found 9/29![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:33 pm -
1 stop6h 47m
Sun 11/296:01 am -
1 stop5h 04m
Deal found 9/27![American Airlines logo]()
$575
Last-minute flights from North Carolina to La CrosseDiscover last-minute flight deals from North Carolina to La Crosse. Data last updated September 30, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to La Crosse. Data last updated September 30, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop6h 22m
Tue 10/67:00 am -
1 stop5h 18m
Deal found 9/27![American Airlines logo]()
$482
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/306:00 am -
1 stop6h 22m
Sat 10/1012:23 pm -
1 stop6h 22m
Deal found 9/27![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/27:47 pm -
1 stop5h 33m
Fri 10/912:23 pm -
1 stop6h 17m
Deal found 9/27![American Airlines logo]()
$560
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/136:28 pm -
1 stop6h 31m
Sat 10/176:58 am -
1 stop7h 16m
Deal found 9/28![American Airlines logo]()
$372
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/138:25 pm -
1 stop4h 34m
Sat 10/176:58 am -
1 stop6h 59m
Deal found 9/28![American Airlines logo]()
$372
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/149:42 pm -
1 stop12h 24m
Sun 10/1811:41 am -
1 stop19h 56m
Deal found 9/29![Multiple Airlines logo]()
$343
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/157:49 am -
1 stop5h 04m
Mon 10/197:04 am -
1 stop7h 10m
Deal found 9/30![American Airlines logo]()
$560
One-way flights from North Carolina to La CrosseSearch for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
Search for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated September 30, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:32 am -
3 stops32h 52m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![Multiple Airlines logo]()
$316
This American Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/119:41 am -
1 stop15h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/29![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/198:25 pm -
1 stop16h 28m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/28![American Airlines logo]()
$382
This American Airlines deal was found by Cheapflights users on 9/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/51:54 pm -
2 stops11h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/25![American Airlines logo]()
$387
Find flight deals from North Carolina to La Crosse
Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated September 30, 2026.
Round-trip from | $300 (American Airlines) |
|---|
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighLa Crosse
RDU Raleigh-Durham - LSE La Crosse
RDULSE
Raleigh-Durham
Sat 11/21
5:00 am-11:56 am
2 stops7h 56m
La Crosse
Tue 11/24
6:50 pm-12:31 am
1 stop4h 41m
$306
CharlotteLa Crosse
CLT Charlotte Douglas - LSE La Crosse
CLTLSE
Charlotte Douglas
Wed 11/11
9:32 am-5:24 pm
3 stops32h 52m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$316
CharlotteLa Crosse
CLT Charlotte Douglas - LSE La Crosse
CLTLSE
Charlotte Douglas
Wed 10/14
9:42 pm-9:06 am
1 stop12h 24m
La Crosse
Sun 10/18
11:41 am-8:37 am
1 stop19h 56m
$343
CharlotteLa Crosse
CLT Charlotte Douglas - LSE La Crosse
CLTLSE
Charlotte Douglas
Tue 10/13
6:28 pm-11:59 pm
1 stop6h 31m
La Crosse
Sat 10/17
6:58 am-3:14 pm
1 stop7h 16m
$372
RaleighLa Crosse
RDU Raleigh-Durham - LSE La Crosse
RDULSE
Raleigh-Durham
Tue 10/13
3:42 pm-11:59 pm
2 stops9h 17m
La Crosse
Sat 10/17
6:58 am-2:57 pm
1 stop6h 59m
$378
CharlotteLa Crosse
CLT Charlotte Douglas - LSE La Crosse
CLTLSE
Charlotte Douglas
Wed 11/11
9:41 am-12:18 am
1 stop15h 37m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$382
Quickest round-trip
RaleighLa Crosse
RDU Raleigh-Durham - LSE La Crosse
RDULSE
Raleigh-Durham
Thu 11/5
9:35 am-6:16 pm
1 stop9h 41m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$382
RaleighLa Crosse
RDU Raleigh-Durham - LSE La Crosse
RDULSE
Raleigh-Durham
Mon 10/19
8:25 pm-11:53 am
1 stop16h 28m
La Crosse
Wed 12/31
12:00 am-1:00 am
Nonstop0h 00m
$382
CharlotteLa Crosse
CLT Charlotte Douglas - LSE La Crosse
CLTLSE
Charlotte Douglas
Wed 11/25
7:31 am-11:56 am
1 stop5h 25m
La Crosse
Sat 11/28
6:50 pm-12:11 am
1 stop4h 21m
$457
RaleighLa Crosse
RDU Raleigh-Durham - LSE La Crosse
RDULSE
Raleigh-Durham
Fri 12/4
10:21 am-6:16 pm
2 stops8h 55m
La Crosse
Sun 12/6
12:24 pm-10:06 pm
2 stops8h 42m
$461
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from North Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
RDU-LSE
CLT-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to La Crosse
USNC-LSE
RDU-LSE
CLT-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Other flights to La Crosse
Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 30, 2026.
North Carolina and La Crosse flights
Browse other North Carolina and La Crosse flight options. Last updated on September 30, 2026.
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North Carolina to La Crosse flights
Consider these flights traveling from North Carolina to La Crosse.
Top airline flying from North Carolina to La Crosse
Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 30, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$270 | Average$480 | FlexibilityNo cancel fee | On-time71% |