$132+ Cheap flights from North Carolina to La Crosse (LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/19. Fares are subject to change and may not be available on all flights or dates of travel.
RDU — LSE
May 7 — May 141
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from North Carolina to La CrosseExplore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Tue 6/25:50 am
LSE
- CLT
1 stop5h 07m
American Airlines
Deal found 4/2![American Airlines logo]()
$270
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:22 am
RDU
- LSE
2 stops7h 27m
American Airlines
Mon 9/216:24 pm
LSE
- RDU
1 stop4h 03m
American Airlines
Deal found 4/6![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Mon 6/155:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/6![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Mon 5/410:05 am
LSE
- TYS
2 stops12h 50m
American Airlines
Deal found 4/3![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:48 pm
RDU
- LSE
1 stop8h 06m
American Airlines
Sun 4/265:40 am
LSE
- RDU
1 stop4h 31m
American Airlines
Deal found 4/6![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:25 pm
CLT
- LSE
1 stop6h 41m
American Airlines
Mon 6/155:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/6![American Airlines logo]()
$363
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:49 pm
ORF
- LSE
2 stops11h 05m
American Airlines
Tue 5/195:40 am
LSE
- ORF
2 stops8h 51m
American Airlines
Deal found 4/5![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:25 pm
CLT
- LSE
1 stop6h 41m
American Airlines
Mon 6/225:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/4![American Airlines logo]()
$428
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:33 pm
GSO
- LSE
1 stop5h 33m
American Airlines
Mon 6/1511:52 am
LSE
- GSO
1 stop6h 11m
American Airlines
Deal found 4/6![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:07 pm
TYS
- LSE
2 stops6h 59m
American Airlines
Mon 6/2211:52 am
LSE
- TYS
2 stops11h 04m
American Airlines
Deal found 4/6![American Airlines logo]()
$486
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/21:43 pm
ORF
- LSE
2 stops10h 53m
American Airlines
Mon 4/65:09 am
LSE
- ORF
1 stop7h 18m
American Airlines
Deal found 4/2![American Airlines logo]()
$494
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Sun 4/265:40 am
LSE
- TYS
1 stop4h 38m
American Airlines
Deal found 4/6![American Airlines logo]()
$496
Best flights from North Carolina to La CrosseDiscover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
Discover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 7, 2026.
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Tue 6/25:50 am
LSE
- CLT
1 stop5h 07m
American Airlines
Deal found 4/2![American Airlines logo]()
$270
This United Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2910:46 am
TYS
- LSE
1 stop8h 24m
United Airlines
Tue 9/18:15 am
LSE
- TYS
2 stops14h 42m
United Airlines
Deal found 4/2![United Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:22 am
RDU
- LSE
2 stops7h 27m
American Airlines
Mon 9/216:24 pm
LSE
- RDU
1 stop4h 03m
American Airlines
Deal found 4/6![American Airlines logo]()
$300
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/138:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Mon 6/155:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/6![American Airlines logo]()
$318
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:48 pm
RDU
- LSE
1 stop8h 06m
American Airlines
Sun 4/265:40 am
LSE
- RDU
1 stop4h 31m
American Airlines
Deal found 4/6![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Mon 5/45:40 am
LSE
- TYS
1 stop4h 38m
American Airlines
Deal found 4/3![American Airlines logo]()
$359
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:25 pm
CLT
- LSE
1 stop6h 41m
American Airlines
Mon 6/155:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/6![American Airlines logo]()
$363
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/137:44 pm
CLT
- LSE
2 stops23h 26m
United Airlines
Mon 6/151:53 pm
LSE
- CLT
1 stop19h 09m
United Airlines
Deal found 4/6![United Airlines logo]()
$632
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:49 pm
ORF
- LSE
2 stops11h 05m
American Airlines
Tue 5/195:40 am
LSE
- ORF
2 stops8h 51m
American Airlines
Deal found 4/5![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/196:25 pm
CLT
- LSE
1 stop6h 41m
American Airlines
Mon 6/225:34 pm
LSE
- CLT
1 stop5h 25m
American Airlines
Deal found 4/4![American Airlines logo]()
$428
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:44 pm
CLT
- LSE
2 stops18h 33m
United Airlines
Mon 6/151:53 pm
LSE
- CLT
2 stops18h 52m
United Airlines
Deal found 4/6![United Airlines logo]()
$712
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/127:33 pm
GSO
- LSE
1 stop5h 33m
American Airlines
Mon 6/1511:52 am
LSE
- GSO
1 stop6h 11m
American Airlines
Deal found 4/6![American Airlines logo]()
$455
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:48 pm
TYS
- LSE
1 stop13h 47m
American Airlines
Sun 4/2610:05 am
LSE
- TYS
2 stops12h 50m
American Airlines
Deal found 4/6![American Airlines logo]()
$532
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/56:19 pm
ORF
- LSE
1 stop6h 47m
American Airlines
Sat 6/1311:44 am
LSE
- ORF
2 stops11h 23m
American Airlines
Deal found 4/6![American Airlines logo]()
$563
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/126:43 pm
TYS
- LSE
1 stop17h 31m
American Airlines
Mon 6/225:34 pm
LSE
- TYS
1 stop18h 00m
American Airlines
Deal found 4/6![American Airlines logo]()
$596
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/201:49 pm
ORF
- LSE
2 stops11h 05m
American Airlines
Fri 4/245:40 am
LSE
- ORF
2 stops7h 37m
American Airlines
Deal found 4/5![American Airlines logo]()
$755
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/266:34 pm
CLT
- LSE
2 stops6h 20m
American Airlines
Mon 4/276:37 pm
LSE
- CLT
1 stop12h 29m
American Airlines
Deal found 4/2![American Airlines logo]()
$1,189
Last-minute flights from North Carolina to La CrosseDiscover last-minute flight deals from North Carolina to La Crosse. Data last updated April 7, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to La Crosse. Data last updated April 7, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Wed 4/1510:05 am
LSE
- CLT
1 stop6h 00m
American Airlines
Deal found 4/3![American Airlines logo]()
$698
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/168:01 pm
ORF
- LSE
1 stop4h 53m
American Airlines
Mon 4/205:40 am
LSE
- ORF
2 stops10h 59m
American Airlines
Deal found 4/3![American Airlines logo]()
$567
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/208:01 pm
ORF
- LSE
1 stop4h 53m
American Airlines
Fri 4/245:40 am
LSE
- ORF
2 stops10h 59m
American Airlines
Deal found 4/5![American Airlines logo]()
$750
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/224:48 pm
RDU
- LSE
1 stop8h 06m
American Airlines
Sun 4/265:40 am
LSE
- RDU
1 stop4h 31m
American Airlines
Deal found 4/6![American Airlines logo]()
$328
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/238:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Sun 4/265:40 am
LSE
- TYS
1 stop4h 38m
American Airlines
Deal found 4/6![American Airlines logo]()
$496
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/263:04 pm
CLT
- LSE
1 stop9h 50m
American Airlines
Mon 4/276:37 pm
LSE
- CLT
1 stop14h 58m
American Airlines
Deal found 4/2![American Airlines logo]()
$773
This American Airlines deal was found by Cheapflights users on 4/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/308:48 pm
TYS
- LSE
1 stop4h 06m
American Airlines
Mon 5/410:05 am
LSE
- TYS
2 stops12h 50m
American Airlines
Deal found 4/3![American Airlines logo]()
$324
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/141:49 pm
ORF
- LSE
2 stops11h 05m
American Airlines
Tue 5/195:40 am
LSE
- ORF
2 stops8h 51m
American Airlines
Deal found 4/5![American Airlines logo]()
$401
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:10 pm
CLT
- LSE
1 stop4h 56m
American Airlines
Tue 6/25:50 am
LSE
- CLT
1 stop5h 07m
American Airlines
Deal found 4/2![American Airlines logo]()
$270
One-way flights from North Carolina to La CrosseSearch for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
Search for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated April 7, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/199:47 pm
RDU
- LSE
1 stop13h 04m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/202:20 pm
TYS
- LSE
1 stop28h 27m
Allegiant Air
Deal found 4/5![Allegiant Air logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/239:47 pm
RDU
- LSE
1 stop13h 04m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$151
This Kiwi.com deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:05 am
RDU
- LSE
2 stops34h 25m
Multiple Airlines
Deal found 4/6![Multiple Airlines logo]()
$213
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 6/67:06 am
RDU
- LSE
1 stop5h 08m
American Airlines
Deal found 4/6![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:00 am
RDU
- LSE
2 stops12h 49m
American Airlines
Deal found 4/6![American Airlines logo]()
$279
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/2010:32 am
RDU
- LSE
2 stops8h 17m
American Airlines
Deal found 4/6![American Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 4/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/203:58 pm
TYS
- LSE
2 stops8h 56m
American Airlines
Deal found 4/5![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 4/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:00 pm
CLT
- LSE
1 stop6h 54m
American Airlines
Deal found 4/4![American Airlines logo]()
$349
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1911:22 am
RDU
- LSE
2 stops7h 27m
American Airlines
Deal found 4/6![American Airlines logo]()
$356
This American Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/48:05 pm
CLT
- LSE
1 stop15h 18m
American Airlines
Deal found 4/6![American Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 4/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/47:44 pm
CLT
- LSE
2 stops18h 21m
United Airlines
Deal found 4/6![United Airlines logo]()
$423
Find flight deals from North Carolina to La Crosse
Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated April 7, 2026.
Round-trip from | $270 (American Airlines) |
|---|---|
One-way from | $132 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Wed 5/27
8:10 pm-12:06 am
1 stop4h 56m
La Crosse
Tue 6/2
5:50 am-11:57 am
1 stop5h 07m
$270
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sat 9/19
11:22 am-5:49 pm
2 stops7h 27m
La Crosse
Mon 9/21
6:24 pm-11:27 pm
1 stop4h 03m
$300
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Sat 6/13
8:10 pm-12:06 am
1 stop4h 56m
La Crosse
Mon 6/15
5:34 pm-11:59 pm
1 stop5h 25m
$318
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Wed 4/22
4:48 pm-11:54 pm
1 stop8h 06m
La Crosse
Sun 4/26
5:40 am-11:11 am
1 stop4h 31m
$328
Quickest round-trip
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Thu 4/30
8:48 pm-11:54 pm
1 stop4h 06m
La Crosse
Mon 5/4
5:40 am-11:18 am
1 stop4h 38m
$359
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Fri 6/12
6:25 pm-12:06 am
1 stop6h 41m
La Crosse
Mon 6/15
5:34 pm-11:59 pm
1 stop5h 25m
$363
NorfolkLa Crosse
ORF - LSE
ORFLSE
Norfolk
Thu 5/14
1:49 pm-11:54 pm
2 stops11h 05m
La Crosse
Tue 5/19
5:40 am-3:31 pm
2 stops8h 51m
$401
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Fri 6/19
6:25 pm-12:06 am
1 stop6h 41m
La Crosse
Mon 6/22
5:34 pm-11:59 pm
1 stop5h 25m
$428
GreensboroLa Crosse
GSO - LSE
GSOLSE
Greensboro/H. Point
Fri 6/12
7:33 pm-12:06 am
1 stop5h 33m
La Crosse
Mon 6/15
11:52 am-7:03 pm
1 stop6h 11m
$455
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Thu 4/23
8:48 pm-9:35 am
1 stop13h 47m
La Crosse
Sun 4/26
10:05 am-11:55 pm
2 stops12h 50m
$532
Showing 1-10 of 29 resultsSorted by cheapest first
Best time to book a flight from North Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
RDU-LSE
TYS-LSE
CLT-LSE
ORF-LSE
GSO-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to La Crosse
USNC-LSE
RDU-LSE
TYS-LSE
CLT-LSE
ORF-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
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Other flights to La Crosse
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North Carolina and La Crosse flights
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North Carolina to La Crosse flights
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Top airline flying from North Carolina to La Crosse
Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 7, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$469 | Average$534 | FlexibilityNo cancel fee | On-time71% |