$148+ Cheap flights from North Carolina to La Crosse (LSE)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
CLT — LSE
Aug 2 — Aug 91
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from North Carolina to La Crosse with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from North Carolina to La Crosse
Cheapest
Best
Last-minute
One-way
Cheapest flights from North Carolina to La CrosseExplore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
Explore the most affordable flight options available from North Carolina to La Crosse. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Wed 7/155:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Deal found 7/1![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:07 pm
RDU
- LSE
1 stop6h 15m
American Airlines
Wed 7/225:53 pm
LSE
- RDU
1 stop4h 49m
American Airlines
Deal found 7/2![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:47 pm
RDU
- LSE
1 stop5h 33m
American Airlines
Mon 9/215:22 pm
LSE
- RDU
1 stop5h 37m
American Airlines
Deal found 6/30![American Airlines logo]()
$345
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Wed 8/125:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 7/1![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/133:52 pm
RDU
- LSE
2 stops9h 28m
American Airlines
Sat 9/2612:26 pm
LSE
- RDU
2 stops7h 34m
American Airlines
Deal found 7/1![American Airlines logo]()
$392
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:02 am
TYS
- LSE
1 stop5h 29m
American Airlines
Sat 8/112:01 pm
LSE
- TYS
2 stops8h 32m
American Airlines
Deal found 7/1![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/176:42 am
ORF
- LSE
1 stop5h 40m
American Airlines
Sun 9/205:22 pm
LSE
- ORF
1 stop5h 37m
American Airlines
Deal found 6/28![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Mon 8/175:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/29![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Fri 8/215:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/30![American Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:49 pm
GSO
- LSE
1 stop6h 32m
American Airlines
Sun 8/165:26 pm
LSE
- GSO
1 stop4h 43m
American Airlines
Deal found 7/1![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:27 pm
GSO
- LSE
2 stops9h 32m
American Airlines
Tue 7/2112:01 pm
LSE
- GSO
1 stop5h 11m
American Airlines
Deal found 7/2![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:31 pm
CLT
- LSE
1 stop4h 51m
American Airlines
Sun 8/165:26 pm
LSE
- CLT
1 stop5h 28m
American Airlines
Deal found 6/30![American Airlines logo]()
$475
Best flights from North Carolina to La CrosseDiscover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
Discover carefully curated flight deals from North Carolina to La Crosse that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 3, 2026.
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/197:47 pm
RDU
- LSE
1 stop5h 33m
American Airlines
Mon 9/215:22 pm
LSE
- RDU
1 stop5h 37m
American Airlines
Deal found 7/2![American Airlines logo]()
$345
This United Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/146:20 am
ORF
- LSE
2 stops16h 04m
United Airlines
Tue 11/178:00 am
LSE
- ORF
2 stops24h 41m
United Airlines
Deal found 7/2![United Airlines logo]()
$629
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/186:29 pm
RDU
- LSE
2 stops6h 53m
American Airlines
Wed 7/226:00 am
LSE
- RDU
1 stop4h 38m
American Airlines
Deal found 7/2![American Airlines logo]()
$348
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/136:20 pm
RDU
- LSE
2 stops7h 00m
American Airlines
Sat 9/265:22 pm
LSE
- RDU
1 stop5h 37m
American Airlines
Deal found 7/1![American Airlines logo]()
$351
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/276:07 pm
TYS
- LSE
2 stops6h 52m
American Airlines
Sat 8/112:01 pm
LSE
- TYS
2 stops8h 32m
American Airlines
Deal found 7/1![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Fri 8/215:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/30![American Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/103:56 pm
RDU
- LSE
2 stops9h 26m
American Airlines
Mon 8/175:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/29![American Airlines logo]()
$426
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:49 pm
GSO
- LSE
1 stop6h 32m
American Airlines
Sun 8/165:26 pm
LSE
- GSO
1 stop4h 43m
American Airlines
Deal found 7/1![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:27 pm
GSO
- LSE
2 stops9h 32m
American Airlines
Tue 7/2112:01 pm
LSE
- GSO
1 stop5h 11m
American Airlines
Deal found 7/2![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:31 pm
CLT
- LSE
1 stop4h 51m
American Airlines
Sun 8/165:26 pm
LSE
- CLT
1 stop5h 28m
American Airlines
Deal found 6/30![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 pm
RDU
- LSE
1 stop4h 34m
American Airlines
Mon 10/2612:23 pm
LSE
- RDU
1 stop6h 22m
American Airlines
Deal found 6/28![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:27 pm
CLT
- LSE
1 stop4h 32m
American Airlines
Mon 7/205:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Deal found 7/1![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/186:00 am
ORF
- LSE
2 stops11h 52m
American Airlines
Sun 9/205:22 pm
LSE
- ORF
1 stop5h 37m
American Airlines
Deal found 6/29![American Airlines logo]()
$558
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:26 pm
CLT
- LSE
1 stop6h 33m
American Airlines
Wed 7/226:00 am
LSE
- CLT
1 stop5h 12m
American Airlines
Deal found 7/1![American Airlines logo]()
$1,089
Last-minute flights from North Carolina to La CrosseDiscover last-minute flight deals from North Carolina to La Crosse. Data last updated July 3, 2026 and is based on user searches.
Discover last-minute flight deals from North Carolina to La Crosse. Data last updated July 3, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:08 am
RDU
- LSE
1 stop5h 23m
American Airlines
Sat 7/185:41 pm
LSE
- RDU
1 stop4h 37m
American Airlines
Deal found 7/3![American Airlines logo]()
$436
This American Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/57:55 pm
GSO
- LSE
1 stop5h 04m
American Airlines
Sat 7/1812:01 pm
LSE
- GSO
2 stops10h 57m
American Airlines
Deal found 7/3![American Airlines logo]()
$536
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/116:26 pm
CLT
- LSE
1 stop6h 56m
American Airlines
Wed 7/155:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Deal found 7/1![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/168:27 pm
CLT
- LSE
1 stop4h 32m
American Airlines
Mon 7/205:53 pm
LSE
- CLT
1 stop5h 06m
American Airlines
Deal found 7/1![American Airlines logo]()
$530
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/173:27 pm
GSO
- LSE
2 stops9h 32m
American Airlines
Tue 7/2112:01 pm
LSE
- GSO
1 stop5h 11m
American Airlines
Deal found 7/2![American Airlines logo]()
$442
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/187:07 pm
RDU
- LSE
1 stop6h 15m
American Airlines
Wed 7/225:53 pm
LSE
- RDU
1 stop4h 49m
American Airlines
Deal found 7/2![American Airlines logo]()
$342
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:02 am
TYS
- LSE
1 stop5h 29m
American Airlines
Sat 8/112:01 pm
LSE
- TYS
2 stops8h 32m
American Airlines
Deal found 7/1![American Airlines logo]()
$406
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Wed 8/125:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 7/1![American Airlines logo]()
$381
This American Airlines deal was found by Cheapflights users on 6/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Mon 8/175:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/29![American Airlines logo]()
$420
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:17 pm
RDU
- LSE
1 stop5h 05m
American Airlines
Fri 8/215:20 pm
LSE
- RDU
1 stop5h 22m
American Airlines
Deal found 6/30![American Airlines logo]()
$421
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:31 pm
CLT
- LSE
1 stop4h 51m
American Airlines
Sun 8/165:26 pm
LSE
- CLT
1 stop5h 28m
American Airlines
Deal found 6/30![American Airlines logo]()
$475
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:49 pm
GSO
- LSE
1 stop6h 32m
American Airlines
Sun 8/165:26 pm
LSE
- GSO
1 stop4h 43m
American Airlines
Deal found 7/1![American Airlines logo]()
$436
One-way flights from North Carolina to La CrosseSearch for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
Search for one-way flight options from North Carolina to La Crosse. Find affordable one-way fares based on user searches. Data last updated July 3, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/222:23 pm
TYS
- LSE
1 stop27h 17m
Allegiant Air
Deal found 7/1![Allegiant Air logo]()
$148
This Kiwi.com deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/61:21 pm
RDU
- LSE
2 stops30h 59m
Multiple Airlines
Deal found 6/28![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/228:19 pm
TYS
- LSE
3 stops47h 55m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$336
This Kiwi.com deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/1412:26 pm
RDU
- LSE
3 stops53h 14m
Multiple Airlines
Deal found 7/2![Multiple Airlines logo]()
$337
This American Airlines deal was found by Cheapflights users on 6/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/67:04 am
RDU
- LSE
1 stop18h 18m
American Airlines
Deal found 6/28![American Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:00 am
TYS
- LSE
3 stops37h 14m
Multiple Airlines
Deal found 7/1![Multiple Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/226:32 pm
TYS
- LSE
1 stop6h 27m
American Airlines
Deal found 7/1![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/146:45 am
RDU
- LSE
1 stop5h 46m
American Airlines
Deal found 7/2![American Airlines logo]()
$489
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/178:17 pm
RDU
- LSE
1 stop16h 14m
American Airlines
Deal found 6/30![American Airlines logo]()
$559
This American Airlines deal was found by Cheapflights users on 6/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/148:17 pm
RDU
- LSE
1 stop19h 25m
American Airlines
Deal found 6/30![American Airlines logo]()
$593
This American Airlines deal was found by Cheapflights users on 7/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/236:32 pm
TYS
- LSE
1 stop6h 27m
American Airlines
Deal found 7/1![American Airlines logo]()
$600
This American Airlines deal was found by Cheapflights users on 7/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:14 pm
RDU
- LSE
1 stop5h 45m
American Airlines
Deal found 7/2![American Airlines logo]()
$600
Find flight deals from North Carolina to La Crosse
Keep the following information in mind while searching for North Carolina to La Crosse flight deals. Data was last updated July 3, 2026.
Round-trip from | $342 (American Airlines) |
|---|---|
One-way from | $148 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from North Carolina to La Crosse that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
Use the filters below to find and compare flights from North Carolina to La Crosse that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sat 9/19
7:47 pm-12:20 am
1 stop5h 33m
La Crosse
Mon 9/21
5:22 pm-11:59 pm
1 stop5h 37m
$345
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sat 7/18
6:29 pm-12:22 am
2 stops6h 53m
La Crosse
Wed 7/22
6:00 am-11:38 am
1 stop4h 38m
$348
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Sun 9/13
6:20 pm-12:20 am
2 stops7h 00m
La Crosse
Sat 9/26
5:22 pm-11:59 pm
1 stop5h 37m
$351
KnoxvilleLa Crosse
TYS - LSE
TYSLSE
Knoxville McGhee Tyson
Mon 7/27
6:07 pm-11:59 pm
2 stops6h 52m
La Crosse
Sat 8/1
12:01 pm-9:33 pm
2 stops8h 32m
$411
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Fri 8/14
8:17 pm-12:22 am
1 stop5h 05m
La Crosse
Fri 8/21
5:20 pm-11:42 pm
1 stop5h 22m
$421
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Mon 8/10
3:56 pm-12:22 am
2 stops9h 26m
La Crosse
Mon 8/17
5:20 pm-11:42 pm
1 stop5h 22m
$426
GreensboroLa Crosse
GSO - LSE
GSOLSE
Greensboro/H. Point
Sat 8/15
6:49 pm-12:21 am
1 stop6h 32m
La Crosse
Sun 8/16
5:26 pm-11:09 pm
1 stop4h 43m
$436
GreensboroLa Crosse
GSO - LSE
GSOLSE
Greensboro/H. Point
Fri 7/17
3:27 pm-11:59 pm
2 stops9h 32m
La Crosse
Tue 7/21
12:01 pm-6:12 pm
1 stop5h 11m
$442
CharlotteLa Crosse
CLT - LSE
CLTLSE
Charlotte Douglas
Fri 8/14
8:31 pm-12:22 am
1 stop4h 51m
La Crosse
Sun 8/16
5:26 pm-11:54 pm
1 stop5h 28m
$475
RaleighLa Crosse
RDU - LSE
RDULSE
Raleigh-Durham
Fri 10/23
8:25 pm-11:59 pm
1 stop4h 34m
La Crosse
Mon 10/26
12:23 pm-7:45 pm
1 stop6h 22m
$475
Showing 1-10 of 24 resultsSorted by cheapest first
Best time to book a flight from North Carolina to La Crosse
Have a flexible travel schedule? Discover the best time to fly to La Crosse from North Carolina with our price prediction graph.
CLT-LSE
RDU-LSE
TYS-LSE
ORF-LSE
GSO-LSE
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from North Carolina to La Crosse
USNC-LSE
CLT-LSE
RDU-LSE
TYS-LSE
ORF-LSE
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from North Carolina to La Crosse. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near La Crosse?
Book flights to La Crosse if you plan to visit one of these locationsDecorah
Winona
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
La Crosse flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for North Carolina to La Crosse
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to La Crosse by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from North Carolina to La Crosse by cabin class
Find flights from North Carolina to La Crosse, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to La Crosse
Explore flights to La Crosse departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on July 3, 2026.
North Carolina and La Crosse flights
Browse other North Carolina and La Crosse flight options. Last updated on July 3, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
North Carolina to La Crosse flights
Consider these flights traveling from North Carolina to La Crosse.
Top airline flying from North Carolina to La Crosse
Discover the top airline that operate flights from North Carolina to La Crosse. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 3, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$330 | Average$514 | FlexibilityNo cancel fee | On-time71% |