$411+ Cheap flights from La Crosse (LSE) to North Carolina
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/29. Fares are subject to change and may not be available on all flights or dates of travel.
LSE — CLT
Nov 18 — Nov 251
Round-trip
1 adult, Economy
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Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Best
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Cheapest flights from La Crosse to North CarolinaExplore the most affordable flight options available from La Crosse to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
Explore the most affordable flight options available from La Crosse to North Carolina. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:50 pm -
1 stop4h 41m
Sat 11/285:50 am -
1 stop7h 06m
Deal found 10/17![American Airlines logo]()
$452
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:57 am -
1 stop4h 18m
Wed 11/187:35 am -
1 stop5h 18m
Deal found 10/15![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:57 am -
2 stops7h 58m
Sat 11/73:35 pm -
2 stops9h 43m
Deal found 10/19![American Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:09 pm -
1 stop6h 30m
Sun 12/68:09 pm -
1 stop5h 21m
Deal found 10/17![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:01 am -
1 stop5h 04m
Sun 11/226:33 pm -
1 stop6h 47m
Deal found 10/15![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/181:04 pm -
2 stops7h 51m
Mon 12/211:15 pm -
1 stop6h 16m
Deal found 10/17![American Airlines logo]()
$673
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/156:52 pm -
1 stop13h 58m
Thu 12/173:04 pm -
1 stop10h 26m
Deal found 10/19![American Airlines logo]()
$887
Best flights from La Crosse to North CarolinaDiscover carefully curated flight deals from La Crosse to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
Discover carefully curated flight deals from La Crosse to North Carolina that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:50 pm -
1 stop4h 41m
Sat 11/285:50 am -
1 stop7h 06m
Deal found 10/15![American Airlines logo]()
$452
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/56:01 am -
2 stops10h 00m
Tue 1/1911:43 am -
2 stops13h 11m
Deal found 10/19![American Airlines logo]()
$463
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:57 am -
1 stop4h 18m
Wed 11/187:35 am -
1 stop5h 18m
Deal found 10/15![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:57 am -
2 stops7h 58m
Sat 11/73:35 pm -
2 stops9h 43m
Deal found 10/19![American Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/312:09 pm -
1 stop6h 30m
Sun 12/68:09 pm -
1 stop5h 21m
Deal found 10/17![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/1912:26 pm -
1 stop6h 41m
Sun 11/226:33 pm -
1 stop6h 47m
Deal found 10/16![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/186:01 am -
1 stop5h 07m
Mon 12/213:04 pm -
1 stop4h 27m
Deal found 10/17![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/45:55 am -
2 stops8h 37m
Tue 1/51:52 pm -
1 stop5h 39m
Deal found 10/14![American Airlines logo]()
$548
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/46:01 am -
2 stops7h 34m
Sat 1/165:04 pm -
2 stops7h 50m
Deal found 10/18![American Airlines logo]()
$594
Last-minute flights from La Crosse to North CarolinaDiscover last-minute flight deals from La Crosse to North Carolina. Data last updated October 19, 2026 and is based on user searches.
Discover last-minute flight deals from La Crosse to North Carolina. Data last updated October 19, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/35:57 am -
2 stops7h 58m
Sat 11/73:35 pm -
2 stops9h 43m
Deal found 10/19![American Airlines logo]()
$527
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/115:57 am -
1 stop4h 18m
Wed 11/187:35 am -
1 stop5h 18m
Deal found 10/15![American Airlines logo]()
$484
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/196:01 am -
1 stop5h 04m
Sun 11/226:33 pm -
1 stop6h 47m
Deal found 10/15![American Airlines logo]()
$542
This American Airlines deal was found by Cheapflights users on 10/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:50 pm -
1 stop4h 41m
Sat 11/285:50 am -
1 stop7h 06m
Deal found 10/17![American Airlines logo]()
$452
One-way flights from La Crosse to North CarolinaSearch for one-way flight options from La Crosse to North Carolina. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
Search for one-way flight options from La Crosse to North Carolina. Find affordable one-way fares based on user searches. Data last updated October 19, 2026.
This American Airlines deal was found by Cheapflights users on 10/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/291:04 pm -
1 stop8h 32m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/15![American Airlines logo]()
$411
This American Airlines deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/47:05 pm -
1 stop15h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![American Airlines logo]()
$438
This American Airlines deal was found by Cheapflights users on 10/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/231:04 pm -
2 stops9h 33m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/19![American Airlines logo]()
$442
This Kiwi.com deal was found by Cheapflights users on 10/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 1/411:58 am -
3 stops48h 54m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 10/18![Multiple Airlines logo]()
$461
Find flight deals from La Crosse to North Carolina
Keep the following information in mind while searching for La Crosse to North Carolina flight deals. Data was last updated October 19, 2026.
Round-trip from | $305 (Kiwi.com) |
|---|---|
Popular in | July |
Cheapest in | May |
Average price | $497 |
Cheapflights Fare Finder
Customize your flight search to find flights from La Crosse to North Carolina that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
Use the filters below to find and compare flights from La Crosse to North Carolina that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
La CrosseRaleigh
LSE La Crosse - RDU Raleigh-Durham
LSERDU
La Crosse
Tue 12/29
1:04 pm-10:36 pm
1 stop8h 32m
Raleigh-Durham
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$411
La CrosseCharlotte
LSE La Crosse - CLT Charlotte Douglas
LSECLT
La Crosse
Mon 1/4
7:05 pm-11:05 am
1 stop15h 00m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$438
La CrosseWilmington
LSE La Crosse - ILM Wilmington New Hanover County
LSEILM
La Crosse
Wed 12/23
1:04 pm-11:37 pm
2 stops9h 33m
Wilmington New Hanover County
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$442
La CrosseRaleigh
LSE La Crosse - RDU Raleigh-Durham
LSERDU
La Crosse
Wed 11/25
6:50 pm-12:31 am
1 stop4h 41m
Raleigh-Durham
Sat 11/28
5:50 am-11:56 am
1 stop7h 06m
$452
La CrosseCharlotte
LSE La Crosse - CLT Charlotte Douglas
LSECLT
La Crosse
Mon 1/4
11:58 am-1:52 pm
3 stops48h 54m
Charlotte Douglas
Wed 12/31
12:00 am-11:00 pm
Nonstop0h 00m
$461
La CrosseWilmington
LSE La Crosse - ILM Wilmington New Hanover County
LSEILM
La Crosse
Tue 1/5
6:01 am-5:01 pm
2 stops10h 00m
Wilmington New Hanover County
Tue 1/19
11:43 am-11:54 pm
2 stops13h 11m
$463
La CrosseCharlotte
LSE La Crosse - CLT Charlotte Douglas
LSECLT
La Crosse
Wed 11/11
5:57 am-11:15 am
1 stop4h 18m
Charlotte Douglas
Wed 11/18
7:35 am-11:53 am
1 stop5h 18m
$484
La CrosseWilmington
LSE La Crosse - ILM Wilmington New Hanover County
LSEILM
La Crosse
Tue 11/3
5:57 am-2:55 pm
2 stops7h 58m
Wilmington New Hanover County
Sat 11/7
3:35 pm-12:18 am
2 stops9h 43m
$527
La CrosseRaleigh
LSE La Crosse - RDU Raleigh-Durham
LSERDU
La Crosse
Thu 12/3
12:09 pm-7:39 pm
1 stop6h 30m
Raleigh-Durham
Sun 12/6
8:09 pm-12:30 am
1 stop5h 21m
$542
La CrosseCharlotte
LSE La Crosse - CLT Charlotte Douglas
LSECLT
La Crosse
Thu 11/19
12:26 pm-8:07 pm
1 stop6h 41m
Charlotte Douglas
Sun 11/22
6:33 pm-12:20 am
1 stop6h 47m
$542
Showing 1-10 of 13 resultsSorted by cheapest first
Best time to book a flight from La Crosse to North Carolina
Have a flexible travel schedule? Discover the best time to fly to North Carolina from La Crosse with our price prediction graph.
LSE-RDU
LSE-ILM
LSE-CLT
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from La Crosse to North Carolina
LSE-USNC
LSE-RDU
LSE-ILM
LSE-CLT
No data available for this route at this time. Please check back soon.
Reviews of airlines servicing North Carolina
Get insights into the airlines that provide service to North Carolina. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to North Carolina. Reviews last updated October 19, 2026.
Read reviews from past customers who have flown American Airlines from La Crosse to North Carolina. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Food
6.4
Comfort
7.1
Crew
7.9
Overall
7.0
Entertainment
6.8
Boarding
7.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Food
6.4
Comfort
7.1
Crew
7.9
Overall
7.0
Entertainment
6.8
Boarding
7.4
Reviews
1 / 20
10.0
ExcellentLinda,Jul 2026
ROA - CLT
Related info for your journey
Find useful and relevant information for your journey from La Crosse to North Carolina. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Alternative routes for La Crosse to North Carolina
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Complete your trip
Complete your trip to North Carolina by adding a car rental and/or hotel reservation to your travel itinerary.
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Find flights from La Crosse to North Carolina, based on your preferred cabin class, be it economy, premium economy, business, or first class.
La Crosse and North Carolina flights
Browse other La Crosse and North Carolina flight options. Last updated on October 19, 2026.
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La Crosse to North Carolina flights
Consider these flights traveling from La Crosse to North Carolina.
Top airline flying from La Crosse to North Carolina
Discover the top airline that operate flights from La Crosse to North Carolina. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$300 | Average$501 | FlexibilityNo cancel fee | On-time71% |