$139+ Cheap flights from Santa Ana to Knoxville (SNA - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/2. Fares are subject to change and may not be available on all flights or dates of travel.
SNA — TYS
Apr 9 — Apr 161
Round-trip
1 adult, Economy
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Find cheap flights from Santa Ana to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Santa Ana to Knoxville
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Best
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Cheapest flights from Santa Ana to KnoxvilleExplore the most affordable flight options available from Santa Ana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
Explore the most affordable flight options available from Santa Ana to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.
This Frontier deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- TYS
1 stop24h 23m
Frontier
Sun 5/104:28 pm
TYS
- SNA
1 stop21h 18m
Frontier
Deal found 3/7![Frontier logo]()
$233
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- TYS
2 stops31h 23m
Multiple Airlines
Sun 5/104:28 pm
TYS
- SNA
1 stop21h 18m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$297
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:15 pm
SNA
- TYS
1 stop8h 26m
United Airlines
Sat 5/94:20 pm
TYS
- SNA
1 stop7h 24m
United Airlines
Deal found 3/5![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/156:45 am
SNA
- TYS
1 stop8h 19m
American Airlines
Tue 4/211:20 pm
TYS
- SNA
1 stop8h 09m
American Airlines
Deal found 3/6![American Airlines logo]()
$309
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:15 am
SNA
- TYS
2 stops9h 20m
Southwest
Sat 5/93:55 pm
TYS
- SNA
1 stop6h 20m
Southwest
Deal found 3/5![Southwest logo]()
$310
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:00 am
SNA
- TYS
2 stops10h 34m
United Airlines
Wed 4/299:00 am
TYS
- SNA
1 stop7h 36m
United Airlines
Deal found 3/6![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:11 pm
SNA
- TYS
1 stop7h 43m
Delta
Wed 4/295:35 am
TYS
- SNA
1 stop9h 26m
Delta
Deal found 3/5![Delta logo]()
$354
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:53 pm
SNA
- TYS
2 stops16h 43m
Multiple Airlines
Thu 4/98:00 am
TYS
- SNA
1 stop29h 05m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$360
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:53 pm
SNA
- TYS
2 stops29h 27m
Multiple Airlines
Mon 4/61:33 pm
TYS
- SNA
1 stop10h 40m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$364
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:23 pm
SNA
- TYS
1 stop7h 33m
American Airlines
Fri 4/173:58 pm
TYS
- SNA
1 stop8h 16m
American Airlines
Deal found 3/8![American Airlines logo]()
$373
Best flights from Santa Ana to KnoxvilleDiscover carefully curated flight deals from Santa Ana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
Discover carefully curated flight deals from Santa Ana to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 10, 2026.
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/159:00 am
SNA
- TYS
2 stops11h 08m
United Airlines
Tue 4/215:53 pm
TYS
- SNA
1 stop7h 42m
United Airlines
Deal found 3/5![United Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:45 am
SNA
- TYS
2 stops9h 55m
Southwest
Sun 5/244:40 pm
TYS
- SNA
1 stop8h 15m
Southwest
Deal found 3/6![Southwest logo]()
$428
This United Airlines deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/27:00 am
SNA
- TYS
2 stops10h 45m
United Airlines
Tue 5/55:55 pm
TYS
- SNA
1 stop7h 40m
United Airlines
Deal found 3/7![United Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/26:45 am
SNA
- TYS
1 stop7h 09m
United Airlines
Thu 5/74:20 pm
TYS
- SNA
1 stop7h 24m
United Airlines
Deal found 3/6![United Airlines logo]()
$421
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/47:45 pm
SNA
- TYS
2 stops14h 10m
Southwest
Wed 4/82:55 pm
TYS
- SNA
2 stops9h 50m
Southwest
Deal found 3/8![Southwest logo]()
$473
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/277:45 am
SNA
- TYS
1 stop7h 22m
United Airlines
Sat 5/308:20 am
TYS
- SNA
2 stops15h 35m
United Airlines
Deal found 3/6![United Airlines logo]()
$440
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3112:15 pm
SNA
- TYS
1 stop8h 26m
United Airlines
Wed 4/17:05 am
TYS
- SNA
1 stop7h 08m
United Airlines
Deal found 3/9![United Airlines logo]()
$463
Last-minute flights from Santa Ana to KnoxvilleDiscover last-minute flight deals from Santa Ana to Knoxville. Data last updated March 10, 2026 and is based on user searches.
Discover last-minute flight deals from Santa Ana to Knoxville. Data last updated March 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/22:53 pm
SNA
- TYS
2 stops29h 27m
Multiple Airlines
Mon 4/61:33 pm
TYS
- SNA
1 stop10h 40m
Multiple Airlines
Deal found 3/7![Multiple Airlines logo]()
$364
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/72:53 pm
SNA
- TYS
2 stops16h 43m
Multiple Airlines
Thu 4/98:00 am
TYS
- SNA
1 stop29h 05m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$360
This Southwest deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/139:10 pm
SNA
- TYS
2 stops11h 50m
Southwest
Wed 4/152:55 pm
TYS
- SNA
1 stop9h 00m
Southwest
Deal found 3/7![Southwest logo]()
$377
This American Airlines deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/141:23 pm
SNA
- TYS
1 stop7h 33m
American Airlines
Fri 4/173:58 pm
TYS
- SNA
1 stop8h 16m
American Airlines
Deal found 3/8![American Airlines logo]()
$373
This Southwest deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/146:45 am
SNA
- TYS
2 stops9h 55m
Southwest
Fri 4/172:45 pm
TYS
- SNA
1 stop7h 50m
Southwest
Deal found 3/8![Southwest logo]()
$378
This United Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1512:15 pm
SNA
- TYS
1 stop8h 26m
United Airlines
Sat 5/94:20 pm
TYS
- SNA
1 stop7h 24m
United Airlines
Deal found 3/5![United Airlines logo]()
$299
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/152:42 pm
SNA
- TYS
1 stop6h 14m
American Airlines
Tue 4/216:00 am
TYS
- SNA
1 stop7h 08m
American Airlines
Deal found 3/5![American Airlines logo]()
$309
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/259:00 am
SNA
- TYS
2 stops10h 34m
United Airlines
Wed 4/299:00 am
TYS
- SNA
1 stop7h 36m
United Airlines
Deal found 3/6![United Airlines logo]()
$314
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/251:11 pm
SNA
- TYS
1 stop7h 43m
Delta
Wed 4/295:35 am
TYS
- SNA
1 stop9h 26m
Delta
Deal found 3/5![Delta logo]()
$354
This Southwest deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/257:15 am
SNA
- TYS
2 stops9h 20m
Southwest
Wed 4/297:05 am
TYS
- SNA
2 stops12h 50m
Southwest
Deal found 3/9![Southwest logo]()
$380
One-way flights from Santa Ana to KnoxvilleSearch for one-way flight options from Santa Ana to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
Search for one-way flight options from Santa Ana to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- TYS
1 stop24h 23m
Frontier
Deal found 3/9![Frontier logo]()
$139
This American Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am
SNA
- TYS
1 stop6h 21m
American Airlines
Deal found 3/10![American Airlines logo]()
$155
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:20 pm
SNA
- TYS
1 stop9h 02m
Delta
Deal found 3/5![Delta logo]()
$159
This United Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/289:00 am
SNA
- TYS
2 stops10h 34m
United Airlines
Deal found 3/6![United Airlines logo]()
$160
This Southwest deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:10 pm
SNA
- TYS
2 stops11h 50m
Southwest
Deal found 3/5![Southwest logo]()
$170
This Kiwi.com deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/282:37 pm
SNA
- TYS
2 stops25h 36m
Frontier
Deal found 3/10![Frontier logo]()
$182
This United Airlines deal was found by Cheapflights users on 3/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:55 pm
SNA
- TYS
1 stop7h 35m
United Airlines
Deal found 3/10![United Airlines logo]()
$187
This Kiwi.com deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/212:10 pm
SNA
- TYS
3 stops29h 25m
Multiple Airlines
Deal found 3/9![Multiple Airlines logo]()
$197
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/311:21 pm
SNA
- TYS
1 stop6h 08m
United Airlines
Deal found 3/9![United Airlines logo]()
$200
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/26:50 am
SNA
- TYS
2 stops11h 40m
United Airlines
Deal found 3/9![United Airlines logo]()
$205
This Delta deal was found by Cheapflights users on 3/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/281:50 pm
SNA
- TYS
1 stop7h 06m
Delta
Deal found 3/8![Delta logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/34:46 pm
SNA
- TYS
2 stops14h 11m
Multiple Airlines
Deal found 3/5![Multiple Airlines logo]()
$213
Find flight deals from Santa Ana to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Santa Ana (SNA) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $233 (Frontier) |
One-way from | $139 (Kiwi.com) |
Popular in | March |
Cheapest in | August |
Average price | $569 |
Cheapflights Fare Finder
Customize your flight search to find flights from Santa Ana to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Santa Ana to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Wed 4/15
9:00 am-11:08 pm
2 stops11h 08m
Knoxville McGhee Tyson
Tue 4/21
5:53 pm-10:35 pm
1 stop7h 42m
$384
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 5/2
7:00 am-8:45 pm
2 stops10h 45m
Knoxville McGhee Tyson
Tue 5/5
5:55 pm-10:35 pm
1 stop7h 40m
$404
Quickest round-trip
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 5/2
6:45 am-4:54 pm
1 stop7h 09m
Knoxville McGhee Tyson
Thu 5/7
4:20 pm-8:44 pm
1 stop7h 24m
$421
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Wed 5/20
6:45 am-7:40 pm
2 stops9h 55m
Knoxville McGhee Tyson
Sun 5/24
4:40 pm-9:55 pm
1 stop8h 15m
$428
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Wed 5/27
7:45 am-6:07 pm
1 stop7h 22m
Knoxville McGhee Tyson
Sat 5/30
8:20 am-8:55 pm
2 stops15h 35m
$440
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Tue 3/31
12:15 pm-11:41 pm
1 stop8h 26m
Knoxville McGhee Tyson
Wed 4/1
7:05 am-11:13 am
1 stop7h 08m
$463
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 4/4
7:45 pm-12:55 pm
2 stops14h 10m
Knoxville McGhee Tyson
Wed 4/8
2:55 pm-9:45 pm
2 stops9h 50m
$473
Cheapest one-way
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Tue 4/28
10:50 am-10:34 pm
1 stop8h 44m
$155
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Mon 4/27
9:20 pm-9:22 am
1 stop9h 02m
$159
Santa AnaKnoxville
SNA - TYS
SNATYS
Santa Ana J. Wayne/Orange Cnty
Sat 5/23
8:00 am-7:31 pm
1 stop8h 31m
$200
Showing 1-10 of 14 resultsSorted by cheapest first
Compare providers for flights from Santa Ana to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Santa Ana to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Santa Ana-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Santa Ana-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Santa Ana-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Santa Ana-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Santa Ana-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Santa Ana to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Santa Ana with our price prediction graph.
SNA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Santa Ana to Knoxville
How far ahead should I book a flight from Santa Ana to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Santa Ana to Knoxville. Price data was last updated on March 6, 2026.
The price you pay for your flight from Santa Ana to Knoxville may vary depending on when you book. For the best chance of a lower fare, look to book 51 days in advance of your trip. Fares are likely to increase a fortnight or so before your departure date.
What is the cheapest month to book a flight from Santa Ana to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Santa Ana to Knoxville (average of $186). Flying from Santa Ana to Knoxville in March is currently the most expensive (average of $296). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 10, 2026.
Peruse reviews from past customers who have flown with Delta,United Airlines, andAmerican Airlines from Santa Ana to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Food
7.2
Comfort
7.9
Entertainment
7.8
Boarding
8.1
Overall
7.9
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from Santa Ana to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Top 3 airlines flying from Santa Ana to Knoxville
Discover the top 3 airlines that operate flights from Santa Ana to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$174 | Average$363 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$283 | Average$462 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$288 | Average$448 | FlexibilityNo cancel fee | On-time69% |