$399+ Cheap flights from San Luis Obispo to Knoxville (SBP - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/17. Fares are subject to change and may not be available on all flights or dates of travel.
SBP — TYS
Nov 4 — Nov 111
Round-trip
1 adult, Economy
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Find cheap flights from San Luis Obispo to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Luis Obispo to Knoxville
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Cheapest flights from San Luis Obispo to KnoxvilleExplore the most affordable flight options available from San Luis Obispo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
Explore the most affordable flight options available from San Luis Obispo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 5, 2026.
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:39 pm -
1 stop8h 02m
Tue 12/225:30 am -
1 stop9h 24m
Deal found 10/1![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:50 pm -
2 stops10h 42m
Tue 10/277:25 am -
1 stop7h 23m
Deal found 10/4![American Airlines logo]()
$444
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/2612:39 pm -
1 stop8h 02m
Wed 12/305:30 am -
2 stops9h 24m
Deal found 10/4![American Airlines logo]()
$549
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:38 pm -
1 stop7h 40m
Mon 10/266:00 am -
1 stop8h 48m
Deal found 10/4![American Airlines logo]()
$610
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:00 am -
1 stop7h 49m
Sat 10/176:00 am -
2 stops12h 22m
Deal found 10/3![United Airlines logo]()
$644
Best flights from San Luis Obispo to KnoxvilleDiscover carefully curated flight deals from San Luis Obispo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
Discover carefully curated flight deals from San Luis Obispo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated October 5, 2026.
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/1712:39 pm -
1 stop8h 02m
Tue 12/225:30 am -
1 stop9h 24m
Deal found 10/3![American Airlines logo]()
$399
This United Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/175:15 am -
1 stop6h 21m
Tue 2/237:00 am -
2 stops9h 43m
Deal found 10/1![United Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/209:43 am -
2 stops10h 36m
Wed 1/275:20 am -
1 stop9h 45m
Deal found 10/3![American Airlines logo]()
$404
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 1/207:10 am -
2 stops11h 49m
Wed 1/2711:53 am -
2 stops10h 58m
Deal found 10/3![United Airlines logo]()
$409
This American Airlines deal was found by Cheapflights users on 10/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/1710:02 am -
2 stops10h 50m
Tue 2/232:50 pm -
2 stops11h 09m
Deal found 10/1![American Airlines logo]()
$409
This United Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/306:00 am -
2 stops12h 05m
Wed 2/36:30 am -
2 stops12h 04m
Deal found 10/4![United Airlines logo]()
$539
Last-minute flights from San Luis Obispo to KnoxvilleDiscover last-minute flight deals from San Luis Obispo to Knoxville. Data last updated October 5, 2026 and is based on user searches.
Discover last-minute flight deals from San Luis Obispo to Knoxville. Data last updated October 5, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:00 am -
1 stop7h 49m
Sat 10/176:00 am -
2 stops12h 22m
Deal found 10/3![United Airlines logo]()
$644
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:38 pm -
1 stop7h 40m
Sat 10/177:25 am -
1 stop7h 23m
Deal found 10/3![American Airlines logo]()
$689
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:38 pm -
1 stop7h 40m
Mon 10/196:00 am -
1 stop8h 48m
Deal found 10/3![American Airlines logo]()
$798
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/145:00 am -
1 stop7h 49m
Mon 10/196:00 am -
2 stops14h 22m
Deal found 10/3![United Airlines logo]()
$800
This American Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/169:45 am -
2 stops10h 33m
Sat 10/176:00 am -
1 stop8h 48m
Deal found 10/3![American Airlines logo]()
$694
This United Airlines deal was found by Cheapflights users on 10/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/167:11 am -
2 stops11h 44m
Sat 10/176:00 am -
2 stops12h 22m
Deal found 10/3![United Airlines logo]()
$775
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2212:38 pm -
1 stop7h 40m
Mon 10/266:00 am -
1 stop8h 48m
Deal found 10/4![American Airlines logo]()
$610
This American Airlines deal was found by Cheapflights users on 10/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/236:50 pm -
2 stops10h 42m
Tue 10/277:25 am -
1 stop7h 23m
Deal found 10/4![American Airlines logo]()
$444
Find flight deals from San Luis Obispo to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 5, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $399 (American Airlines) |
Popular in | May |
Cheapest in | August |
Average price | $563 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Thu 12/17
12:39 pm-11:41 pm
1 stop8h 02m
Knoxville McGhee Tyson
Tue 12/22
5:30 am-11:54 am
1 stop9h 24m
$399
Quickest round-trip
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 2/17
5:15 am-2:36 pm
1 stop6h 21m
Knoxville McGhee Tyson
Tue 2/23
7:00 am-1:43 pm
2 stops9h 43m
$404
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 1/20
9:43 am-11:19 pm
2 stops10h 36m
Knoxville McGhee Tyson
Wed 1/27
5:20 am-12:05 pm
1 stop9h 45m
$404
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 1/20
7:10 am-9:59 pm
2 stops11h 49m
Knoxville McGhee Tyson
Wed 1/27
11:53 am-7:51 pm
2 stops10h 58m
$409
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 2/17
10:02 am-11:52 pm
2 stops10h 50m
Knoxville McGhee Tyson
Tue 2/23
2:50 pm-10:59 pm
2 stops11h 09m
$409
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Sat 1/30
6:00 am-9:05 pm
2 stops12h 05m
Knoxville McGhee Tyson
Wed 2/3
6:30 am-3:34 pm
2 stops12h 04m
$539
Sorted by cheapest first
Compare providers for flights from San Luis Obispo to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Luis Obispo to Knoxville in October.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Luis Obispo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Luis Obispo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Luis Obispo-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Luis Obispo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Luis Obispo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Luis Obispo to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Obispo with our price prediction graph.
SBP-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 5, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Luis Obispo to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Food
6.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Food
6.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Crew
8.1
Entertainment
7.1
Overall
7.4
Food
6.7
Comfort
7.3
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on October 5, 2026.
San Luis Obispo and Knoxville flights
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Popular flight searches
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Top 2 airlines flying from San Luis Obispo to Knoxville
Discover the top 2 airlines that operate flights from San Luis Obispo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated October 5, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$314 | Average$566 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$349 | Average$478 | FlexibilityNo cancel fee | On-time69% |