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$379+ Cheap flights from San Luis Obispo to Knoxville (SBP - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/13. Fares are subject to change and may not be available on all flights or dates of travel.
SBP — TYS
Sep 14 — Sep 211
Mon 9/14
Mon 9/21
1 adult, Economy
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Cheap flight deals from San Luis Obispo to Knoxville

Cheapest flights from San Luis Obispo to Knoxville
Explore the most affordable flight options available from San Luis Obispo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 15, 2026.

This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1312:38 pm -
1 stop7h 40m
Tue 10/277:25 am -
1 stop7h 23m
Deal found 8/11$379
This United Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2912:55 pm -
1 stop6h 34m
Wed 9/24:50 pm -
1 stop7h 10m
Deal found 8/14$459
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/112:55 pm -
1 stop6h 34m
Sat 9/59:00 am -
1 stop7h 24m
Deal found 8/11$489

Find flight deals from San Luis Obispo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 15, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$379
(American Airlines)

Popular in

May

Cheapest in

October

Average price

$334
Provider with most accurate pricing for San Luis Obispo County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Luis Obispo County-Knoxville McGhee Tyson flights.
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From San Luis Obispo County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 13% potential increase in price ($71 potential increase over avg. RT price).
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Cheapest flight prices on average. 5% potential price decrease ($22 potential savings vs. average RT price).
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Average for round-trip flights in August 2026
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

San Luis ObispoKnoxville

SBP San Luis Obispo County - TYS Knoxville McGhee Tyson

SBPTYS

San Luis Obispo County

Tue 10/13

9:45 am-11:18 pm

2 stops10h 33m

Knoxville McGhee Tyson

Tue 10/27

7:25 am-11:48 am

1 stop7h 23m

$384
Quickest round-trip

San Luis ObispoKnoxville

SBP San Luis Obispo County - TYS Knoxville McGhee Tyson

SBPTYS

San Luis Obispo County

Sat 8/29

12:55 pm-10:29 pm

1 stop6h 34m

Knoxville McGhee Tyson

Wed 9/2

4:50 pm-9:00 pm

1 stop7h 10m

$459

San Luis ObispoKnoxville

SBP San Luis Obispo County - TYS Knoxville McGhee Tyson

SBPTYS

San Luis Obispo County

Tue 9/1

8:00 am-10:29 pm

2 stops11h 29m

Knoxville McGhee Tyson

Sat 9/5

4:50 pm-9:00 pm

1 stop7h 10m

$494
Cheapest one-way
Quickest one-way

San Luis ObispoKnoxville

SBP San Luis Obispo County - TYS Knoxville McGhee Tyson

SBPTYS

San Luis Obispo County

Tue 8/25

5:00 am-8:24 pm

2 stops12h 24m

$475

San Luis ObispoKnoxville

SBP San Luis Obispo County - TYS Knoxville McGhee Tyson

SBPTYS

San Luis Obispo County

Tue 8/25

10:11 am-8:10 pm

3 stops30h 59m

$709

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/11

Sorted by cheapest first

Compare providers for flights from San Luis Obispo to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Luis Obispo to Knoxville in August.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Luis Obispo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Luis Obispo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Luis Obispo-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Luis Obispo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Luis Obispo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Luis Obispo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Obispo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 15, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Luis Obispo to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
10,111 reviews

Food

6.7

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
United Airlines
7.4
Good
10,111 reviews
United Airlines
7.4
Good
10,111 reviews

Food

6.7

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.
American Airlines
7.1
Good
11,941 reviews
United Airlines
7.4
Good
10,111 reviews

Food

6.7

Boarding

7.7

Crew

8.1

Entertainment

7.1

Comfort

7.3

Overall

7.4

Reviews

1 / 20
4.0
Okay

Dynasty,May 2026

LAX - EWR

The food wasn’t nice - Hosts were not that kind.

Related info for your journey

Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Luis Obispo to Knoxville?

    Departing from San Luis Obispo to Knoxville will take you 6h 34m. The distance between San Luis Obispo and Knoxville is about 2048 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Luis Obispo to Knoxville round-trip?

    According to our current data, American Airlines ($308), and United Airlines ($349) offers the cheapest pricing from San Luis Obispo to Knoxville. Users have found that American Airlines is 32% cheaper than the other options available to this destination.

  • Can I find deals for flights from San Luis Obispo to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Obispo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Obispo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Obispo to Knoxville.

  • Can I find deals for business class flights from San Luis Obispo to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Obispo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Top 2 airlines flying from San Luis Obispo to Knoxville

Discover the top 2 airlines that operate flights from San Luis Obispo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 15, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$308Average$562FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$349Average$478FlexibilityNo cancel feeOn-time69%

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