
Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 12, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $419 (United Airlines) |
One-way from | $399 (United Airlines) |
Popular in | November |
Cheapest in | August |
Average price | $963 |
Fly from
Fly to
Route
Depart
Return
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Mon 12/7
1:03 pm-10:50 pm
1 stop6h 47m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Tue 12/8
12:36 pm-11:40 pm
1 stop8h 04m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 12/9
1:03 pm-10:50 pm
1 stop6h 47m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Mon 12/7
6:00 am-8:43 pm
2 stops11h 43m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Tue 12/8
8:00 am-8:47 pm
2 stops9h 47m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 3/3
5:00 am-2:33 pm
1 stop6h 33m
Knoxville McGhee Tyson
Wed 3/10
4:25 pm-9:24 pm
1 stop7h 59m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Mon 12/7
12:36 pm-11:40 pm
1 stop8h 04m
Knoxville McGhee Tyson
Mon 12/14
5:30 am-11:43 am
1 stop9h 13m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Wed 3/3
12:38 pm-11:53 pm
1 stop8h 15m
Knoxville McGhee Tyson
Wed 3/10
2:52 pm-10:22 pm
2 stops10h 30m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Mon 12/7
1:03 pm-10:50 pm
1 stop6h 47m
Knoxville McGhee Tyson
Mon 12/14
10:57 am-5:52 pm
2 stops9h 55m
San Luis ObispoKnoxville
SBP San Luis Obispo County - TYS Knoxville McGhee Tyson
SBPTYS
San Luis Obispo County
Tue 1/5
7:05 am-9:59 pm
2 stops11h 54m
Knoxville McGhee Tyson
Sat 1/9
6:01 am-1:33 pm
2 stops10h 32m
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars |
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Dynasty,May 2026
LAX - EWR
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Dynasty,May 2026
LAX - EWR
Comfort
Food
Overall
Crew
Entertainment
Boarding
Reviews
Dynasty,May 2026
LAX - EWR
Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$314 | Average$596 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$349 | Average$504 | FlexibilityNo cancel fee | On-time69% |