HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$369+ Cheap flights from San Luis Obispo to Knoxville (SBP - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/10. Fares are subject to change and may not be available on all flights or dates of travel.
SBP — TYS
Apr 13 — Apr 201
Mon 4/13
Mon 4/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Luis Obispo to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Luis Obispo to Knoxville

Cheapest flights from San Luis Obispo to Knoxville
Explore the most affordable flight options available from San Luis Obispo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 14, 2026.

This American Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1012:55 pm
SBP
-
TYS
1 stop8h 01m
American Airlines
Fri 4/176:00 am
TYS
-
SBP
1 stop9h 10m
American Airlines
Deal found 3/11$369
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:00 am
SBP
-
TYS
1 stop7h 06m
United Airlines
Fri 4/1711:25 am
TYS
-
SBP
2 stops13h 10m
United Airlines
Deal found 3/11$401
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/305:00 am
SBP
-
TYS
1 stop7h 06m
United Airlines
Wed 4/154:30 pm
TYS
-
SBP
2 stops10h 14m
United Airlines
Deal found 3/11$404
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/315:00 am
SBP
-
TYS
2 stops11h 56m
United Airlines
Wed 4/154:30 pm
TYS
-
SBP
2 stops10h 14m
United Airlines
Deal found 3/11$409
This United Airlines deal was found by Cheapflights users on 3/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/26:05 pm
SBP
-
TYS
2 stops13h 00m
United Airlines
Sat 8/84:56 pm
TYS
-
SBP
1 stop6h 54m
United Airlines
Deal found 3/11$424
This American Airlines deal was found by Cheapflights users on 3/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/1212:59 pm
SBP
-
TYS
1 stop7h 57m
American Airlines
Wed 5/206:00 am
TYS
-
SBP
1 stop9h 07m
American Airlines
Deal found 3/13$450
This United Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/105:15 am
SBP
-
TYS
1 stop6h 21m
United Airlines
Sat 11/148:45 am
TYS
-
SBP
1 stop7h 58m
United Airlines
Deal found 3/9$469

Find flight deals from San Luis Obispo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 14, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$369
(American Airlines)

Popular in

May

Cheapest in

October

Average price

$476
Provider with most accurate pricing for San Luis Obispo County-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Luis Obispo County-Knoxville McGhee Tyson flights.
Search Deals
From San Luis Obispo County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 18% potential increase in price ($100 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($18 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Tue 3/31

5:00 am-3:06 pm

1 stop7h 06m

Knoxville McGhee Tyson

Wed 4/15

4:30 pm-11:44 pm

2 stops10h 14m

$404

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Mon 3/30

5:00 am-3:06 pm

1 stop7h 06m

Knoxville McGhee Tyson

Wed 4/15

4:30 pm-11:44 pm

2 stops10h 14m

$404

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Tue 5/12

12:59 pm-11:56 pm

1 stop7h 57m

Knoxville McGhee Tyson

Wed 5/20

6:00 am-4:02 pm

2 stops13h 02m

$511

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Fri 4/10

8:02 am-10:34 pm

2 stops11h 32m

Knoxville McGhee Tyson

Fri 4/17

5:15 pm-11:44 pm

2 stops9h 29m

$513

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sat 3/28

5:00 am-3:02 pm

1 stop7h 02m

Knoxville McGhee Tyson

Wed 4/1

11:25 am-9:35 pm

2 stops13h 10m

$515

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sun 8/2

6:05 pm-10:05 am

2 stops13h 00m

Knoxville McGhee Tyson

Sat 8/8

3:25 pm-11:44 pm

2 stops11h 19m

$521

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Fri 4/24

7:20 am-11:56 pm

2 stops13h 36m

Knoxville McGhee Tyson

Mon 4/27

4:09 pm-11:15 pm

2 stops10h 06m

$539

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Tue 8/11

10:52 am-11:57 pm

2 stops10h 05m

Knoxville McGhee Tyson

Mon 8/17

10:46 am-7:47 pm

2 stops12h 01m

$554

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Tue 5/12

5:52 pm-10:49 am

2 stops13h 57m

Knoxville McGhee Tyson

Wed 5/20

7:00 am-5:11 pm

2 stops13h 11m

$590
Cheapest one-way
Quickest one-way

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Mon 3/30

5:00 am-3:06 pm

1 stop7h 06m

$477

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/11

Sorted by cheapest first

Compare providers for flights from San Luis Obispo to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Luis Obispo to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Luis Obispo-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Luis Obispo-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Luis Obispo-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Luis Obispo-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Luis Obispo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Luis Obispo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Obispo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Luis Obispo to Knoxville

What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

Currently, August is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $248). Flying from San Luis Obispo to Knoxville in March is currently the most expensive (average of $416). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 14, 2026.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Luis Obispo to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,427 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
United Airlines
7.4
Good
9,427 reviews
United Airlines
7.4
Good
9,427 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.
American Airlines
7.1
Good
11,472 reviews
United Airlines
7.4
Good
9,427 reviews

Food

6.6

Comfort

7.3

Overall

7.4

Boarding

7.7

Crew

8.1

Entertainment

7.1

Reviews

1 / 20
10.0
Excellent

Dane,Jan 2026

IAD - TYS

It was a short flight on a small express plane, so no time for amenities. Quickly on, quickly off. No complaints.

Related info for your journey

Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Luis Obispo to Knoxville?

    Departing from San Luis Obispo to Knoxville will take you 7h 06m. The distance between San Luis Obispo and Knoxville is about 2048 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Luis Obispo to Knoxville round-trip?

    According to our current data, United Airlines ($278), and American Airlines ($287) offers the cheapest pricing from San Luis Obispo to Knoxville. Users have found that United Airlines is 38% cheaper than the other options available to this destination.

  • Can I find deals for flights from San Luis Obispo to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Obispo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Obispo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Obispo to Knoxville.

  • Can I find deals for business class flights from San Luis Obispo to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Obispo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $248). Flying from San Luis Obispo to Knoxville in March is currently the most expensive (average of $416). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Luis Obispo to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Nashville flights
San Francisco to Nashville flights
Ontario to Nashville flights
San Diego to Nashville flights
Burbank to Nashville flights
Santa Ana to Nashville flights
Sacramento to Nashville flights
Los Angeles to Memphis flights
Las Vegas to Nashville flights
San Jose to Nashville flights
Los Angeles to Knoxville flights
Long Beach to Nashville flights
San Francisco to Knoxville flights
Oakland to Nashville flights
San Francisco to Memphis flights
Fresno to Nashville flights
San Diego to Memphis flights
Ontario to Memphis flights
Ontario to Knoxville flights
Sacramento to Knoxville flights
Palm Springs to Nashville flights
Las Vegas to Memphis flights
San Diego to Knoxville flights
San Luis Obispo to Nashville flights
San Jose to Memphis flights
San Francisco to Chattanooga flights
Burbank to Knoxville flights
Los Angeles to Chattanooga flights
Santa Ana to Knoxville flights
Reno to Nashville flights
Oakland to Memphis flights
Santa Barbara to Nashville flights
Sacramento to Memphis flights
San Jose to Knoxville flights
Ontario to Chattanooga flights
Las Vegas to Knoxville flights
Fresno to Knoxville flights
Bakersfield to Nashville flights
Oakland to Knoxville flights
Santa Rosa to Nashville flights
Medford to Nashville flights
Santa Ana to Memphis flights
Monterey to Nashville flights
Santa Ana to Chattanooga flights
Sacramento to Chattanooga flights
Long Beach to Memphis flights
Las Vegas to Chattanooga flights
Ontario to Blountville flights

Top 2 airlines flying from San Luis Obispo to Knoxville

Discover the top 2 airlines that operate flights from San Luis Obispo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 14, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$278Average$533FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$287Average$429FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.