HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$358+ Cheap flights from San Luis Obispo to Knoxville (SBP - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/29. Fares are subject to change and may not be available on all flights or dates of travel.
SBP — TYS
ago. 19 — ago. 261
mar. 8/19
mar. 8/26
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Luis Obispo to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from San Luis Obispo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated agosto 14, 2025.

Round-trip from

$419
(United Airlines)

One-way from

$358
(American Airlines)

Popular in

October

Cheapest in

December

Average price

$338
From San Luis Obispo County to Knoxville McGhee Tyson
Search Deals
One-way flight from San Luis Obispo County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 22% potential increase in price ($159 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 13% potential price decrease ($63 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in August 2025
Search Deals

Find flight deals from San Luis Obispo to Knoxville

Cheapest flights from San Luis Obispo to Knoxville
Explore the most affordable flight options available from San Luis Obispo to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on agosto 14, 2025.

This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/236:25 pmSBP - TYS
2 stops12h 40mUnited Airlines
jue. 11/275:45 amTYS - SBP
2 stops10h 42mUnited Airlines
Deal found 8/11$419
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/237:11 pmSBP - TYS
2 stops10h 23mAmerican Airlines
mié. 12/35:46 amTYS - SBP
1 stop9h 01mAmerican Airlines
Deal found 8/11$444
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/227:11 pmSBP - TYS
2 stops10h 23mAmerican Airlines
mié. 12/35:46 amTYS - SBP
1 stop9h 01mAmerican Airlines
Deal found 8/11$485
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 11/226:07 pmSBP - TYS
2 stops12h 58mUnited Airlines
jue. 11/278:26 amTYS - SBP
2 stops12h 00mUnited Airlines
Deal found 8/11$508
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 11/2112:28 pmSBP - TYS
1 stop8h 24mAmerican Airlines
mié. 12/35:46 amTYS - SBP
1 stop9h 01mAmerican Airlines
Deal found 8/11$533
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 11/2512:28 pmSBP - TYS
1 stop8h 24mAmerican Airlines
mié. 12/35:46 amTYS - SBP
1 stop9h 01mAmerican Airlines
Deal found 8/11$536
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 11/275:15 amSBP - TYS
2 stops12h 05mUnited Airlines
mié. 12/34:30 pmTYS - SBP
1 stop7h 42mUnited Airlines
Deal found 8/11$568
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
dom. 11/237:11 pmSBP - TYS
2 stops10h 23mAmerican Airlines
mar. 12/25:10 amTYS - SBP
2 stops13h 26mAmerican Airlines
Deal found 8/11$576

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.

Fly from

San Luis Obispo

Fly to

Knoxville

Route

Depart

Return

Price

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

dom. 11/23

6:25 pm-10:05 am

2 stops12h 40m

Knoxville McGhee Tyson

jue. 11/27

5:45 am-1:27 pm

2 stops10h 42m

$419

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mar. 11/25

6:07 pm-10:48 am

2 stops13h 41m

Knoxville McGhee Tyson

jue. 11/27

5:45 am-1:27 pm

2 stops10h 42m

$419

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

lun. 11/24

6:07 pm-10:48 am

2 stops13h 41m

Knoxville McGhee Tyson

jue. 11/27

5:45 am-1:27 pm

2 stops10h 42m

$419

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

lun. 11/24

7:11 pm-8:34 am

2 stops10h 23m

Knoxville McGhee Tyson

mié. 12/3

5:46 am-11:47 am

1 stop9h 01m

$444

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

dom. 11/23

7:11 pm-8:34 am

2 stops10h 23m

Knoxville McGhee Tyson

mié. 12/3

5:46 am-11:47 am

1 stop9h 01m

$444

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 11/22

7:11 pm-8:34 am

2 stops10h 23m

Knoxville McGhee Tyson

mié. 12/3

5:46 am-11:47 am

1 stop9h 01m

$485

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mié. 11/26

9:53 am-11:45 pm

2 stops10h 52m

Knoxville McGhee Tyson

mié. 12/3

5:46 am-11:47 am

1 stop9h 01m

$485

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

mar. 11/25

9:53 am-11:45 pm

2 stops10h 52m

Knoxville McGhee Tyson

mié. 12/3

5:46 am-11:47 am

1 stop9h 01m

$485

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 11/22

6:07 pm-10:05 am

2 stops12h 58m

Knoxville McGhee Tyson

jue. 11/27

8:26 am-5:26 pm

2 stops12h 00m

$508

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

sáb. 11/29

12:28 pm-11:52 pm

1 stop8h 24m

$358

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/14

Showing 1-10 of 11 results
1
2

Best time to book a flight from San Luis Obispo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Obispo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Luis Obispo to Knoxville

What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $294). Flying from San Luis Obispo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SBP to TYS?

Find hourly flight availability from San Luis Obispo to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated agosto 14, 2025.

It’s optimal to fly from San Luis Obispo to Knoxville at noon. By choosing this option you can save up to 7% on the cost of your flight, compared to a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated agosto 14, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Luis Obispo to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.
United Airlines
7.4
Good
8,916 reviews
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.
American Airlines
7.2
Good
10,000 reviews
United Airlines
7.4
Good
8,916 reviews

Boarding

7.7

Comfort

7.3

Entertainment

7.1

Food

6.6

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.

Related info for your journey

Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Luis Obispo to Knoxville round-trip?

    According to our current data, American Airlines ($248), and United Airlines ($278) offers the cheapest pricing from San Luis Obispo to Knoxville. Users have found that American Airlines is 54% cheaper than the other options available to this destination.

  • Can I find deals for flights from San Luis Obispo to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Obispo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Obispo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Obispo to Knoxville.

  • Can I find deals for business class flights from San Luis Obispo to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Obispo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $294). Flying from San Luis Obispo to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Luis Obispo to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Los Angeles to Nashville flights
San Francisco to Nashville flights
Ontario to Nashville flights
Santa Ana to Nashville flights
Burbank to Nashville flights
San Diego to Nashville flights
Sacramento to Nashville flights
Los Angeles to Memphis flights
Santa Ana to Knoxville flights
San Luis Obispo to Nashville flights
Los Angeles to Knoxville flights
Oakland to Nashville flights
San Jose to Nashville flights
Las Vegas to Nashville flights
Long Beach to Nashville flights
Palm Springs to Nashville flights
Ontario to Knoxville flights
Ontario to Memphis flights
San Francisco to Knoxville flights
Burbank to Knoxville flights
Santa Ana to Memphis flights
Fresno to Nashville flights
San Diego to Knoxville flights
Burbank to Memphis flights
Las Vegas to Memphis flights
Sacramento to Knoxville flights
Reno to Nashville flights
Bakersfield to Nashville flights
Los Angeles to Chattanooga flights
San Diego to Memphis flights
San Jose to Knoxville flights
San Francisco to Memphis flights
San Diego to Chattanooga flights
Las Vegas to Knoxville flights
Ontario to Chattanooga flights
Fresno to Knoxville flights
Medford to Nashville flights
San Jose to Memphis flights
Oakland to Memphis flights
Las Vegas to Chattanooga flights
San Francisco to Chattanooga flights
Reno to Knoxville flights
Santa Ana to Chattanooga flights
Oakland to Knoxville flights
Sacramento to Memphis flights
Santa Barbara to Nashville flights
Monterey to Nashville flights
San Jose to Chattanooga flights
Fresno to Memphis flights
Medford to Knoxville flights

Top 2 airlines flying from San Luis Obispo to Knoxville

Discover the top 2 airlines that operate flights from San Luis Obispo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated agosto 14, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$393FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$278Average$687FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.