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$329+ Cheap flights from San Luis Obispo to Knoxville (SBP - TYS)

This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/21. Fares are subject to change and may not be available on all flights or dates of travel.
SBP — TYS
Jan 30 — Feb 61
Fri 1/30
Fri 2/6
1 adult, Economy
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Cheap flight deals from San Luis Obispo to Knoxville

Best flights from San Luis Obispo to Knoxville
Discover carefully curated flight deals from San Luis Obispo to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 31, 2025.

This American Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/2112:45 pmSBP - TYS
1 stop8h 43mAmerican Airlines
Sat 2/285:40 amTYS - SBP
1 stop9h 22mAmerican Airlines
Deal found 12/28$329
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/105:00 amSBP - TYS
1 stop7h 14mUnited Airlines
Sat 1/244:25 pmTYS - SBP
1 stop7h 50mUnited Airlines
Deal found 12/28$409
This United Airlines deal was found by Cheapflights users on 12/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/35:00 amSBP - TYS
1 stop7h 14mUnited Airlines
Sat 2/74:25 pmTYS - SBP
1 stop7h 50mUnited Airlines
Deal found 12/28$429

Find flight deals from San Luis Obispo to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Luis Obispo (SBP) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated December 31, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$329
(American Airlines)

Popular in

June

Cheapest in

October

Average price

$391
Provider with most accurate pricing for San Luis Obispo County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Luis Obispo County-Knoxville McGhee Tyson flights.
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From San Luis Obispo County to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 23% potential increase in price ($139 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($18 potential savings vs. average RT price).
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Average for round-trip flights in December 2025
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Cheapflights Fare Finder

 
Customize your flight search to find flights from San Luis Obispo to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
Use the filters below to find and compare flights from San Luis Obispo to Knoxville that are best for you.

Fly from

San Luis Obispo

Fly to

Knoxville

Route

Depart

Return

Price

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sat 2/21

12:45 pm-12:28 am

1 stop8h 43m

Knoxville McGhee Tyson

Sat 2/28

5:40 am-12:02 pm

1 stop9h 22m

$329

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sat 1/10

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sat 1/24

4:25 pm-9:15 pm

1 stop7h 50m

$409

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Tue 2/3

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Sat 2/7

4:25 pm-9:15 pm

1 stop7h 50m

$429

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Wed 5/6

12:56 pm-11:56 pm

1 stop8h 00m

$353

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Mon 5/4

12:56 pm-11:56 pm

1 stop8h 00m

$353

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sat 1/10

1:03 pm-10:47 pm

1 stop6h 44m

$430

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Sat 1/10

6:17 pm-10:28 pm

3 stops49h 11m

$563

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Wed 5/6

7:20 am-9:11 am

3 stops22h 51m

$599

San Luis ObispoKnoxville

SBP - TYS

SBPTYS

San Luis Obispo County

Mon 5/4

7:20 am-11:15 am

3 stops48h 55m

$643

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/29

Compare providers for flights from San Luis Obispo to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Luis Obispo to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Luis Obispo-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Luis Obispo-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Luis Obispo-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Luis Obispo-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Luis Obispo-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Luis Obispo to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Luis Obispo with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Luis Obispo to Knoxville

What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

Currently, August is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $248). Flying from San Luis Obispo to Knoxville in November is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated December 31, 2025.
Peruse reviews from past customers who have flown with United Airlines and American Airlines from San Luis Obispo to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,124 reviews

Comfort

7.3

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.
United Airlines
7.4
Good
9,124 reviews
United Airlines
7.4
Good
9,124 reviews

Comfort

7.3

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.
American Airlines
7.2
Good
11,074 reviews
United Airlines
7.4
Good
9,124 reviews

Comfort

7.3

Food

6.6

Boarding

7.7

Entertainment

7.1

Overall

7.4

Crew

8.1

Reviews

1 / 20
10.0
Excellent

Kathy,Jun 2024

RDD - SFO

United has consistently been good. Every now and then there is a crew member that should probably retire, but most of them are excellent.

Related info for your journey

Find useful and relevant information for your journey from San Luis Obispo to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Luis Obispo to Knoxville?

    Departing from San Luis Obispo to Knoxville will take you 7h 14m. The distance between San Luis Obispo and Knoxville is about 2048 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Luis Obispo to Knoxville round-trip?

    According to our current data, American Airlines ($254), and United Airlines ($278) offers the cheapest pricing from San Luis Obispo to Knoxville. Users have found that American Airlines is 44% cheaper than the other options available to this destination.

  • Can I find deals for flights from San Luis Obispo to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Luis Obispo to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Luis Obispo to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Luis Obispo to Knoxville.

  • Can I find deals for business class flights from San Luis Obispo to Knoxville?

    Yes. Cheapflights offers flight deals from San Luis Obispo to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Luis Obispo to Knoxville?

    Currently, August is the cheapest month in which you can book a flight from San Luis Obispo to Knoxville (average of $248). Flying from San Luis Obispo to Knoxville in November is currently the most expensive (average of $516). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from San Luis Obispo to Knoxville

Discover the top 2 airlines that operate flights from San Luis Obispo to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 31, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$254Average$415FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$278Average$583FlexibilityNo cancel feeOn-time69%

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