$87+ Cheap flights from San Antonio to Knoxville (SAT - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Apr 26 — May 31
Round-trip
1 adult, Economy
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Find cheap flights from San Antonio to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Knoxville
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Best
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Cheapest flights from San Antonio to KnoxvilleExplore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 27, 2026.
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:35 pm
SAT
- TYS
1 stop6h 05m
Southwest
Sat 4/255:40 pm
TYS
- SAT
1 stop6h 30m
Southwest
Deal found 3/22![Southwest logo]()
$190
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/55:20 am
SAT
- TYS
1 stop4h 57m
Delta
Wed 5/64:38 pm
TYS
- SAT
1 stop4h 52m
Delta
Deal found 3/23![Delta logo]()
$217
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:18 pm
SAT
- TYS
1 stop6h 12m
United Airlines
Sat 5/305:57 pm
TYS
- SAT
1 stop5h 58m
United Airlines
Deal found 3/23![United Airlines logo]()
$218
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
SAT
- TYS
1 stop5h 30m
American Airlines
Sat 5/24:09 pm
TYS
- SAT
1 stop7h 43m
American Airlines
Deal found 3/25![American Airlines logo]()
$219
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Thu 4/164:28 pm
TYS
- SAT
1 stop22h 47m
Frontier
Deal found 3/23![Frontier logo]()
$226
This Delta deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:20 am
SAT
- TYS
1 stop4h 57m
Delta
Mon 5/117:33 pm
TYS
- SAT
1 stop6h 11m
Delta
Deal found 3/24![Delta logo]()
$232
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/95:25 am
SAT
- TYS
1 stop4h 44m
Delta
Mon 5/117:33 pm
TYS
- SAT
1 stop6h 11m
Delta
Deal found 3/23![Delta logo]()
$234
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Fri 4/104:20 pm
TYS
- SAT
1 stop8h 59m
Frontier
Deal found 3/22![Frontier logo]()
$235
Best flights from San Antonio to KnoxvilleDiscover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
Discover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated March 27, 2026.
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:35 pm
SAT
- TYS
1 stop6h 05m
Southwest
Sat 4/255:40 pm
TYS
- SAT
1 stop6h 30m
Southwest
Deal found 3/22![Southwest logo]()
$190
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/24:16 pm
SAT
- TYS
1 stop6h 28m
United Airlines
Wed 5/67:05 am
TYS
- SAT
1 stop7h 11m
United Airlines
Deal found 3/26![United Airlines logo]()
$285
This Delta deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/65:20 am
SAT
- TYS
1 stop4h 57m
Delta
Sun 5/107:33 pm
TYS
- SAT
1 stop6h 11m
Delta
Deal found 3/23![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 3/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/99:15 am
SAT
- TYS
2 stops8h 15m
Southwest
Tue 5/125:50 pm
TYS
- SAT
1 stop6h 25m
Southwest
Deal found 3/24![Southwest logo]()
$195
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:33 pm
SAT
- TYS
1 stop4h 21m
Delta
Wed 4/155:40 am
TYS
- SAT
1 stop6h 41m
Delta
Deal found 3/26![Delta logo]()
$304
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/227:00 am
SAT
- TYS
1 stop4h 05m
Southwest
Sun 7/267:05 am
TYS
- SAT
2 stops7h 15m
Southwest
Deal found 3/25![Southwest logo]()
$367
Last-minute flights from San Antonio to KnoxvilleDiscover last-minute flight deals from San Antonio to Knoxville. Data last updated March 27, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Knoxville. Data last updated March 27, 2026 and is based on user searches.
This Priceline deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/36:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Fri 4/104:20 pm
TYS
- SAT
1 stop8h 59m
Frontier
Deal found 3/22![Frontier logo]()
$240
This CheapOair deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Thu 4/164:28 pm
TYS
- SAT
1 stop22h 47m
Frontier
Deal found 3/23![Frontier logo]()
$226
This Frontier deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Fri 4/104:20 pm
TYS
- SAT
1 stop8h 59m
Frontier
Deal found 3/22![Frontier logo]()
$235
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/135:42 pm
SAT
- TYS
1 stop5h 13m
American Airlines
Wed 4/154:09 pm
TYS
- SAT
1 stop7h 43m
American Airlines
Deal found 3/25![American Airlines logo]()
$244
This Southwest deal was found by Cheapflights users on 3/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2112:35 pm
SAT
- TYS
1 stop6h 05m
Southwest
Sat 4/255:40 pm
TYS
- SAT
1 stop6h 30m
Southwest
Deal found 3/22![Southwest logo]()
$190
This American Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/225:00 am
SAT
- TYS
1 stop6h 30m
American Airlines
Wed 4/296:54 pm
TYS
- SAT
1 stop4h 58m
American Airlines
Deal found 3/23![American Airlines logo]()
$245
This American Airlines deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:00 am
SAT
- TYS
1 stop5h 30m
American Airlines
Sat 5/24:09 pm
TYS
- SAT
1 stop7h 43m
American Airlines
Deal found 3/25![American Airlines logo]()
$219
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:55 am
SAT
- TYS
1 stop6h 25m
Southwest
Sat 5/26:40 am
TYS
- SAT
2 stops6h 45m
Southwest
Deal found 3/25![Southwest logo]()
$236
One-way flights from San Antonio to KnoxvilleSearch for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
Search for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated March 27, 2026.
This American Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:20 am
SAT
- TYS
1 stop8h 25m
American Airlines
Deal found 3/26![American Airlines logo]()
$87
This Delta deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/196:50 am
SAT
- TYS
1 stop6h 43m
Delta
Deal found 3/26![Delta logo]()
$109
This Priceline deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/136:45 am
SAT
- TYS
1 stop7h 43m
Frontier
Deal found 3/25![Frontier logo]()
$111
This Southwest deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/209:40 am
SAT
- TYS
2 stops9h 00m
Southwest
Deal found 3/26![Southwest logo]()
$134
This United Airlines deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:57 pm
SAT
- TYS
1 stop4h 15m
United Airlines
Deal found 3/23![United Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/197:54 pm
SAT
- TYS
3 stops21h 05m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$184
This United Airlines deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/46:02 pm
SAT
- TYS
1 stop4h 39m
United Airlines
Deal found 3/27![United Airlines logo]()
$185
This Kiwi.com deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/207:54 pm
SAT
- TYS
3 stops24h 02m
Multiple Airlines
Deal found 3/26![Multiple Airlines logo]()
$194
This Southwest deal was found by Cheapflights users on 3/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/255:55 am
SAT
- TYS
2 stops7h 15m
Southwest
Deal found 3/23![Southwest logo]()
$204
This Southwest deal was found by Cheapflights users on 3/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:10 am
SAT
- TYS
2 stops9h 05m
Southwest
Deal found 3/25![Southwest logo]()
$215
This United Airlines deal was found by Cheapflights users on 3/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/14:17 pm
SAT
- TYS
1 stop6h 24m
United Airlines
Deal found 3/26![United Airlines logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 3/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/41:22 pm
SAT
- TYS
3 stops41h 48m
Multiple Airlines
Deal found 3/27![Multiple Airlines logo]()
$228
Find flight deals from San Antonio to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 27, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $190 (Southwest) |
One-way from | $87 (American Airlines) |
Popular in | March |
Cheapest in | October |
Average price | $489 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 4/21
12:35 pm-7:40 pm
1 stop6h 05m
Knoxville McGhee Tyson
Sat 4/25
5:40 pm-11:10 pm
1 stop6h 30m
$190
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 5/9
9:15 am-6:30 pm
2 stops8h 15m
Knoxville McGhee Tyson
Tue 5/12
5:50 pm-11:15 pm
1 stop6h 25m
$195
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 5/2
4:16 pm-11:44 pm
1 stop6h 28m
Knoxville McGhee Tyson
Wed 5/6
7:05 am-1:16 pm
1 stop7h 11m
$285
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 5/6
5:20 am-11:17 am
1 stop4h 57m
Knoxville McGhee Tyson
Sun 5/10
7:33 pm-12:44 am
1 stop6h 11m
$287
Quickest round-trip
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 4/13
6:33 pm-11:54 pm
1 stop4h 21m
Knoxville McGhee Tyson
Wed 4/15
5:40 am-11:21 am
1 stop6h 41m
$304
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 7/22
7:00 am-12:05 pm
1 stop4h 05m
Knoxville McGhee Tyson
Sun 7/26
7:05 am-1:20 pm
2 stops7h 15m
$367
Cheapest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 5/19
6:50 am-2:33 pm
1 stop6h 43m
$109
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 4/13
6:45 am-3:28 pm
1 stop7h 43m
$111
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 5/20
9:40 am-7:40 pm
2 stops9h 00m
$134
Quickest one-way
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 5/25
5:57 pm-11:12 pm
1 stop4h 15m
$165
Showing 1-10 of 16 resultsSorted by cheapest first
Compare providers for flights from San Antonio to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in March.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
SAT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Knoxville
How far ahead should I book a flight from San Antonio to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Knoxville. Price data was last updated on March 13, 2026.
Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Antonio to Knoxville?
Currently, September is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $79). Flying from San Antonio to Knoxville in February is currently the most expensive (average of $223). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
How much does it cost to fly round-trip from San Antonio to Knoxville?
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 27, 2026.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Delta,United Airlines, andAmerican Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Overall
7.9
Food
7.2
Boarding
8.1
Entertainment
7.8
Comfort
7.9
Crew
8.5
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on March 27, 2026.
San Antonio and Knoxville flights
Browse other San Antonio and Knoxville flight options. Last updated on March 27, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on March 27, 2026.
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Top 3 airlines flying from San Antonio to Knoxville
Discover the top 3 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 27, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$316 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$359 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$293 | Average$374 | FlexibilityNo cancel fee | On-time69% |