$109+ Cheap flights from San Antonio to Knoxville (SAT - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 3/11. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Mar 13 — Mar 201
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from San Antonio to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from San Antonio to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from San Antonio to KnoxvilleExplore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:25 pm
SAT
- TYS
1 stop22h 02m
Frontier
Mon 2/238:13 pm
TYS
- SAT
1 stop21h 28m
Frontier
Deal found 2/10![Frontier logo]()
$213
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:40 pm
SAT
- TYS
1 stop6h 29m
United Airlines
Sat 6/66:30 am
TYS
- SAT
1 stop6h 37m
United Airlines
Deal found 2/9![United Airlines logo]()
$217
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:45 am
SAT
- TYS
1 stop7h 40m
Frontier
Fri 3/274:20 pm
TYS
- SAT
1 stop8h 57m
Frontier
Deal found 2/9![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:22 am
SAT
- TYS
1 stop11h 04m
Multiple Airlines
Mon 3/308:58 am
TYS
- SAT
1 stop25h 29m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$235
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/206:45 am
SAT
- TYS
1 stop6h 48m
Delta
Sun 5/245:39 am
TYS
- SAT
1 stop5h 13m
Delta
Deal found 2/8![Delta logo]()
$243
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:22 pm
SAT
- TYS
1 stop22h 02m
Multiple Airlines
Mon 4/206:20 pm
TYS
- SAT
1 stop29h 09m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$257
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:15 pm
SAT
- TYS
1 stop7h 05m
American Airlines
Sun 3/225:40 am
TYS
- SAT
1 stop4h 53m
American Airlines
Deal found 2/9![American Airlines logo]()
$258
This Delta deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/16:45 am
SAT
- TYS
1 stop6h 48m
Delta
Thu 6/43:00 pm
TYS
- SAT
1 stop8h 27m
Delta
Deal found 2/8![Delta logo]()
$269
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/1412:15 pm
SAT
- TYS
1 stop4h 58m
Delta
Thu 10/157:20 pm
TYS
- SAT
1 stop6h 08m
Delta
Deal found 2/9![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/1612:15 pm
SAT
- TYS
1 stop4h 58m
Delta
Fri 10/237:20 pm
TYS
- SAT
1 stop6h 08m
Delta
Deal found 2/11![Delta logo]()
$279
Best flights from San Antonio to KnoxvilleDiscover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
Discover carefully curated flight deals from San Antonio to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:25 pm
SAT
- TYS
1 stop22h 02m
Frontier
Mon 2/238:13 pm
TYS
- SAT
1 stop21h 28m
Frontier
Deal found 2/10![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:22 am
SAT
- TYS
1 stop11h 04m
Multiple Airlines
Mon 3/308:58 am
TYS
- SAT
1 stop25h 29m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$235
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:29 pm
SAT
- TYS
1 stop6h 23m
Delta
Sat 2/285:35 am
TYS
- SAT
1 stop5h 15m
Delta
Deal found 2/9![Delta logo]()
$299
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:13 am
SAT
- TYS
1 stop7h 18m
American Airlines
Wed 2/256:21 pm
TYS
- SAT
1 stop5h 33m
American Airlines
Deal found 2/11![American Airlines logo]()
$314
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:10 pm
SAT
- TYS
1 stop4h 45m
United Airlines
Sat 2/286:45 am
TYS
- SAT
2 stops9h 53m
United Airlines
Deal found 2/9![United Airlines logo]()
$321
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:45 am
SAT
- TYS
1 stop7h 40m
Frontier
Fri 3/274:20 pm
TYS
- SAT
1 stop8h 57m
Frontier
Deal found 2/9![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:22 pm
SAT
- TYS
1 stop22h 02m
Multiple Airlines
Mon 4/206:20 pm
TYS
- SAT
1 stop29h 09m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
SAT
- TYS
1 stop11h 32m
Multiple Airlines
Sun 2/225:56 pm
TYS
- SAT
2 stops23h 22m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$303
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
SAT
- TYS
1 stop11h 31m
Multiple Airlines
Mon 3/29:36 pm
TYS
- SAT
1 stop12h 54m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$308
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:22 am
SAT
- TYS
1 stop26h 48m
Multiple Airlines
Fri 3/276:20 am
TYS
- SAT
2 stops28h 07m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$324
Last-minute flights from San Antonio to KnoxvilleDiscover last-minute flight deals from San Antonio to Knoxville. Data last updated February 11, 2026 and is based on user searches.
Discover last-minute flight deals from San Antonio to Knoxville. Data last updated February 11, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 2/189:13 am
SAT
- TYS
1 stop7h 18m
American Airlines
Wed 2/256:21 pm
TYS
- SAT
1 stop5h 33m
American Airlines
Deal found 2/11![American Airlines logo]()
$314
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/198:25 pm
SAT
- TYS
1 stop22h 02m
Frontier
Mon 2/238:13 pm
TYS
- SAT
1 stop21h 28m
Frontier
Deal found 2/10![Frontier logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
SAT
- TYS
1 stop11h 32m
Multiple Airlines
Sun 2/225:56 pm
TYS
- SAT
2 stops23h 22m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$303
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/244:29 pm
SAT
- TYS
1 stop6h 23m
Delta
Sat 2/285:35 am
TYS
- SAT
1 stop5h 15m
Delta
Deal found 2/9![Delta logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/242:10 pm
SAT
- TYS
1 stop4h 45m
United Airlines
Sat 2/286:45 am
TYS
- SAT
2 stops9h 53m
United Airlines
Deal found 2/9![United Airlines logo]()
$321
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
SAT
- TYS
1 stop11h 31m
Multiple Airlines
Mon 3/29:36 pm
TYS
- SAT
1 stop12h 54m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/173:15 pm
SAT
- TYS
1 stop7h 05m
American Airlines
Sun 3/225:40 am
TYS
- SAT
1 stop4h 53m
American Airlines
Deal found 2/9![American Airlines logo]()
$258
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1710:22 am
SAT
- TYS
1 stop23h 18m
Multiple Airlines
Sun 3/226:12 pm
TYS
- SAT
2 stops43h 15m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$316
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/236:45 am
SAT
- TYS
1 stop7h 40m
Frontier
Fri 3/274:20 pm
TYS
- SAT
1 stop8h 57m
Frontier
Deal found 2/9![Frontier logo]()
$224
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/2310:22 am
SAT
- TYS
1 stop26h 48m
Multiple Airlines
Fri 3/276:20 am
TYS
- SAT
2 stops28h 07m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$324
This Kiwi.com deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 3/2610:22 am
SAT
- TYS
1 stop11h 04m
Multiple Airlines
Mon 3/308:58 am
TYS
- SAT
1 stop25h 29m
Multiple Airlines
Deal found 2/8![Multiple Airlines logo]()
$235
One-way flights from San Antonio to KnoxvilleSearch for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
Search for one-way flight options from San Antonio to Knoxville. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:13 am
SAT
- TYS
1 stop4h 04m
Delta
Deal found 2/9![Delta logo]()
$109
This Southwest deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:55 am
SAT
- TYS
2 stops8h 10m
Southwest
Deal found 2/9![Southwest logo]()
$114
This Southwest deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:15 am
SAT
- TYS
2 stops10h 15m
Southwest
Deal found 2/11![Southwest logo]()
$120
This American Airlines deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/117:00 am
SAT
- TYS
1 stop4h 30m
American Airlines
Deal found 2/11![American Airlines logo]()
$130
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 2/286:00 am
SAT
- TYS
1 stop11h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$150
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/1110:26 am
SAT
- TYS
3 stops34h 01m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$165
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/2710:48 pm
SAT
- TYS
3 stops46h 19m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$175
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/111:22 pm
SAT
- TYS
3 stops31h 35m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$252
Find flight deals from San Antonio to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated February 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $217 (United Airlines) |
One-way from | $109 (Delta) |
Popular in | March |
Cheapest in | October |
Average price | $407 |
Cheapflights Fare Finder
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.
Fly from
San Antonio
Fly to
Knoxville
Route
Depart
Return
Price
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 2/19
8:25 pm-7:27 pm
1 stop22h 02m
Knoxville McGhee Tyson
Mon 2/23
8:13 pm-4:41 pm
1 stop21h 28m
$213
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 3/23
6:45 am-3:25 pm
1 stop7h 40m
Knoxville McGhee Tyson
Fri 3/27
4:20 pm-12:17 am
1 stop8h 57m
$224
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Thu 3/26
10:22 am-10:26 pm
1 stop11h 04m
Knoxville McGhee Tyson
Mon 3/30
8:58 am-9:27 am
1 stop25h 29m
$235
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Sat 4/11
1:22 pm-12:24 pm
1 stop22h 02m
Knoxville McGhee Tyson
Mon 4/20
6:20 pm-10:29 pm
1 stop29h 09m
$257
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 2/24
4:29 pm-11:52 pm
1 stop6h 23m
Knoxville McGhee Tyson
Sat 2/28
5:35 am-9:50 am
1 stop5h 15m
$299
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 2/20
6:00 am-6:32 pm
1 stop11h 32m
Knoxville McGhee Tyson
Sun 2/22
5:56 pm-4:18 pm
2 stops23h 22m
$303
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Fri 2/27
6:00 am-6:31 pm
1 stop11h 31m
Knoxville McGhee Tyson
Mon 3/2
9:36 pm-9:30 am
1 stop12h 54m
$308
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Wed 2/18
9:13 am-5:31 pm
1 stop7h 18m
Knoxville McGhee Tyson
Wed 2/25
6:21 pm-10:54 pm
1 stop5h 33m
$314
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Tue 2/24
2:10 pm-7:55 pm
1 stop4h 45m
Knoxville McGhee Tyson
Sat 2/28
6:45 am-3:38 pm
2 stops9h 53m
$321
San AntonioKnoxville
SAT - TYS
SATTYS
San Antonio
Mon 3/23
10:22 am-2:10 pm
1 stop26h 48m
Knoxville McGhee Tyson
Fri 3/27
6:20 am-9:27 am
2 stops28h 07m
$324
Showing 1-10 of 18 results
Compare providers for flights from San Antonio to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in February.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from San Antonio to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
SAT-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from San Antonio to Knoxville
How far ahead should I book a flight from San Antonio to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Knoxville. Price data was last updated on February 6, 2026.
Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.
What is the cheapest month to book a flight from San Antonio to Knoxville?
Currently, September is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $80). Flying from San Antonio to Knoxville in January is currently the most expensive (average of $184). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 11, 2026.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Comfort
7.9
Overall
7.9
Crew
8.5
Boarding
8.1
Entertainment
7.8
Food
7.2
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Knoxville flight routes
Other flight options
Other flights from San Antonio
Popular flights
Alternative routes for San Antonio to Knoxville
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from San Antonio to Knoxville by cabin class
Find flights from San Antonio to Knoxville, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
San Antonio and Knoxville flights
Browse other San Antonio and Knoxville flight options. Last updated on February 11, 2026.
Other flights from San Antonio
Browse through other flights departing from San Antonio. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from San Antonio to Knoxville
Discover the top 3 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$144 | Average$319 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$216 | Average$368 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$278 | Average$369 | FlexibilityNo cancel fee | On-time69% |