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$109+ Cheap flights from San Antonio to Knoxville (SAT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/27. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Oct 30 — Nov 61
Thu 10/30
Thu 11/6
1 adult, Economy
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Cheapflights Tip: The best prices from San Antonio to Knoxville McGhee Tyson are usually found in January or October, booked 73 days in advance, depart on a Wednesday or Tuesday and return on a Friday

Cheap flight deals from San Antonio to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 30, 2025.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$216
(Booking.com)

One-way from

$109
(United Airlines)

Popular in

March

Cheapest in

January

Average price

$356
Provider with most accurate pricing for San Antonio-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for San Antonio-Knoxville McGhee Tyson flights.
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From San Antonio to Knoxville McGhee Tyson
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One-way flight from San Antonio to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 9% potential increase in price ($36 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from San Antonio to Knoxville

Cheapest flights from San Antonio to Knoxville
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 30, 2025.

This Booking.com deal was found by Cheapflights users on 9/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/168:26 pmSAT - TYS
1 stop22h 06mFrontier
Thu 10/307:17 pmTYS - SAT
1 stop25h 13mFrontier
Deal found 9/27$216
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/14:37 pmSAT - TYS
1 stop6h 46mAmerican Airlines
Tue 11/46:05 amTYS - SAT
1 stop7h 31mAmerican Airlines
Deal found 9/30$217
This American Airlines deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/216:00 amSAT - TYS
1 stop4h 45mAmerican Airlines
Tue 11/45:07 pmTYS - SAT
1 stop7h 52mAmerican Airlines
Deal found 9/30$243
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/114:16 pmSAT - TYS
1 stop15h 17mMultiple Airlines
Mon 12/151:05 pmTYS - SAT
1 stop10h 22mMultiple Airlines
Deal found 9/28$264
This Kiwi.com deal was found by Cheapflights users on 9/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/77:37 pmSAT - TYS
1 stop13h 27mMultiple Airlines
Mon 11/106:11 pmTYS - SAT
1 stop25h 21mMultiple Airlines
Deal found 9/28$267
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/229:47 amSAT - TYS
1 stop7h 23mUnited Airlines
Sat 10/257:15 amTYS - SAT
1 stop4h 34mUnited Airlines
Deal found 9/29$269
This United Airlines deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/145:56 pmSAT - TYS
1 stop4h 47mUnited Airlines
Sat 10/187:15 amTYS - SAT
1 stop4h 34mUnited Airlines
Deal found 9/29$279
This Kiwi.com deal was found by Cheapflights users on 9/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/304:55 pmSAT - TYS
1 stop29h 11mMultiple Airlines
Tue 11/411:23 amTYS - SAT
1 stop8h 09mMultiple Airlines
Deal found 9/29$280
This Kiwi.com deal was found by Cheapflights users on 9/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/13:12 pmSAT - TYS
2 stops31h 30mMultiple Airlines
Tue 11/411:23 amTYS - SAT
1 stop8h 09mMultiple Airlines
Deal found 9/30$287

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 30, 2025.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.

Fly from

San Antonio

Fly to

Knoxville

Route

Depart

Return

Price

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 10/16

8:26 pm-7:32 pm

1 stop22h 06m

Knoxville McGhee Tyson

Thu 10/30

7:17 pm-7:30 pm

1 stop25h 13m

$216

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 11/1

6:40 pm-12:23 am

1 stop4h 43m

Knoxville McGhee Tyson

Tue 11/4

7:20 pm-12:28 am

1 stop6h 08m

$217

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 1/21

5:59 pm-11:44 pm

1 stop4h 45m

Knoxville McGhee Tyson

Sat 1/24

4:55 pm-10:57 pm

1 stop7h 02m

$217

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 2/21

5:30 am-1:26 pm

1 stop6h 56m

Knoxville McGhee Tyson

Wed 2/25

6:45 am-12:19 pm

1 stop6h 34m

$237

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Fri 11/7

7:37 pm-10:04 am

1 stop13h 27m

Knoxville McGhee Tyson

Mon 11/10

6:11 pm-6:32 pm

1 stop25h 21m

$267

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 10/22

9:47 am-6:10 pm

1 stop7h 23m

Knoxville McGhee Tyson

Sat 10/25

7:15 am-10:49 am

1 stop4h 34m

$269

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 11/20

6:00 am-11:24 am

1 stop4h 24m

Knoxville McGhee Tyson

Mon 11/24

5:10 am-9:46 am

1 stop5h 36m

$269

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Mon 10/27

6:00 am-11:44 am

1 stop4h 44m

Knoxville McGhee Tyson

Mon 11/3

5:07 pm-11:59 pm

1 stop7h 52m

$269

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 11/27

2:14 pm-8:09 pm

1 stop4h 55m

$109

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 12/11

4:16 pm-8:33 am

1 stop15h 17m

$134

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/30

Showing 1-10 of 15 results
1
2

Compare providers for flights from San Antonio to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in September.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Knoxville

How far ahead should I book a flight from San Antonio to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Knoxville. Price data was last updated on September 26, 2025.

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Antonio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $294). Flying from San Antonio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to TYS?

Find hourly flight availability from San Antonio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 30, 2025.

A simple way to save on the total cost of your ticket is to fly from San Antonio to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 30, 2025.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,964 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,964 reviews
Delta
8.0
Very good
7,964 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,931 reviews
Delta
8.0
Very good
7,964 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,964 reviews

Comfort

7.9

Entertainment

7.9

Overall

8.0

Boarding

8.2

Crew

8.5

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Knoxville?

    Airlines like Frontier, American Airlines, and United Airlines fly from San Antonio to Knoxville in about 4h 43m. The time it takes to get you to your destination can typically vary by up to 17h 23m. The distance between San Antonio and Knoxville is about 945 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines flying from San Antonio to Knoxville round-trip?

    Our cheapest airline available from San Antonio to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $144 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $232 and $259 round-trip. You may be able to fly from San Antonio to Knoxville for 59% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Antonio to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Antonio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Knoxville.

  • Can I find deals for business class flights from San Antonio to Knoxville?

    Yes. Cheapflights offers flight deals from San Antonio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $294). Flying from San Antonio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from San Antonio to Knoxville

Discover the top 3 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 30, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$144Average$313FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$232Average$368FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$259Average$408FlexibilityNo cancel feeOn-time69%

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