HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$118+ Cheap flights from San Antonio to Knoxville (SAT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/8. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Dec 13 — Dec 201
Sat 12/13
Sat 12/20
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from San Antonio to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheapflights Tip: The best prices from San Antonio to Knoxville McGhee Tyson are usually found in October or January, booked 73 days in advance, depart on a Wednesday or Tuesday and return on a Friday

Cheap flight deals from San Antonio to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 13, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$217
(Delta)

One-way from

$118
(Delta)

Popular in

March

Cheapest in

October

Average price

$392
Provider with most accurate pricing for San Antonio-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for San Antonio-Knoxville McGhee Tyson flights.
Search Deals
From San Antonio to Knoxville McGhee Tyson
Search Deals
One-way flight from San Antonio to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 12% potential increase in price ($48 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($11 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in November 2025
Search Deals

Find flight deals from San Antonio to Knoxville

Cheapest flights from San Antonio to Knoxville
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 13, 2025.

This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/227:00 amSAT - TYS
1 stop11h 10mMultiple Airlines
Wed 11/261:06 pmTYS - SAT
1 stop25h 17mMultiple Airlines
Deal found 11/12$184
This Delta deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/105:20 amSAT - TYS
1 stop5h 27mDelta
Wed 12/1710:23 amTYS - SAT
1 stop6h 24mDelta
Deal found 11/12$217
This Delta deal was found by Cheapflights users on 11/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/35:20 amSAT - TYS
1 stop5h 27mDelta
Sun 12/77:59 pmTYS - SAT
1 stop5h 35mDelta
Deal found 11/13$243
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/207:38 pmSAT - TYS
2 stops19h 15mMultiple Airlines
Sun 11/236:30 amTYS - SAT
1 stop18h 50mMultiple Airlines
Deal found 11/12$251
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/89:14 amSAT - TYS
1 stop5h 18mAmerican Airlines
Sun 12/214:29 pmTYS - SAT
1 stop7h 30mAmerican Airlines
Deal found 11/12$252
This American Airlines deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/244:30 pmSAT - TYS
1 stop6h 50mAmerican Airlines
Thu 11/275:10 amTYS - SAT
1 stop5h 33mAmerican Airlines
Deal found 11/11$258
This Kiwi.com deal was found by Cheapflights users on 11/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/47:56 pmSAT - TYS
2 stops24h 53mMultiple Airlines
Sun 12/76:30 amTYS - SAT
1 stop13h 41mMultiple Airlines
Deal found 11/11$260
This Kiwi.com deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/273:23 pmSAT - TYS
1 stop23h 30mMultiple Airlines
Mon 12/111:29 amTYS - SAT
1 stop29h 30mMultiple Airlines
Deal found 11/12$269
This American Airlines deal was found by Cheapflights users on 11/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/255:00 amSAT - TYS
1 stop5h 22mAmerican Airlines
Tue 12/95:24 amTYS - SAT
1 stop5h 17mAmerican Airlines
Deal found 11/12$273

Cheapflights Fare Finder

 
Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.

Fly from

San Antonio

Fly to

Knoxville

Route

Depart

Return

Price

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 1/10

7:45 am-3:11 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sat 1/24

10:07 am-3:22 pm

1 stop6h 15m

$217

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Tue 1/13

5:30 am-12:13 pm

1 stop5h 43m

Knoxville McGhee Tyson

Tue 2/3

6:19 am-12:13 pm

1 stop6h 54m

$217

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 11/22

11:05 am-7:10 pm

1 stop7h 05m

Knoxville McGhee Tyson

Wed 11/26

1:06 pm-2:28 pm

2 stops26h 22m

$218

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Tue 1/13

11:43 am-7:50 pm

1 stop7h 07m

Knoxville McGhee Tyson

Tue 2/3

1:59 pm-9:21 pm

2 stops8h 22m

$222

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Mon 11/24

7:21 am-3:07 pm

1 stop6h 46m

Knoxville McGhee Tyson

Tue 12/2

6:38 pm-10:26 pm

1 stop4h 48m

$243

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 12/3

6:30 am-1:44 pm

1 stop6h 14m

Knoxville McGhee Tyson

Sun 12/7

7:59 pm-12:34 am

1 stop5h 35m

$243

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Mon 12/8

4:33 pm-11:59 pm

1 stop6h 26m

Knoxville McGhee Tyson

Sun 12/21

6:20 pm-10:59 pm

1 stop5h 39m

$252

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 12/4

11:51 am-8:00 pm

1 stop7h 09m

Knoxville McGhee Tyson

Sun 12/7

7:59 pm-12:34 am

1 stop5h 35m

$252

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 1/8

7:45 am-3:21 pm

1 stop6h 36m

$118

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 1/10

7:45 am-3:11 pm

1 stop6h 26m

$118

Flights are sorted by cheapest round-trip flights first.

Deals found on 11/11

Showing 1-10 of 14 results
1
2

Compare providers for flights from San Antonio to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from San Antonio to Knoxville in November.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on San Antonio-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on San Antonio-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from San Antonio-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on San Antonio-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for San Antonio-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from San Antonio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Knoxville

How far ahead should I book a flight from San Antonio to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Knoxville. Price data was last updated on November 7, 2025.

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Antonio to Knoxville?

Currently, September is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $79). Flying from San Antonio to Knoxville in January is currently the most expensive (average of $125). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to TYS?

Find hourly flight availability from San Antonio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 13, 2025.

A simple way to save on the total cost of your ticket is to fly from San Antonio to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 25% on your trip compared to booking a flight in the morning.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 13, 2025.
Read through reviews of airlines operating flights from San Antonio to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,017 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,051 reviews
Delta
7.9
Good
8,007 reviews

Crew

8.5

Overall

7.9

Entertainment

7.9

Boarding

8.1

Comfort

7.9

Food

7.3

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from San Antonio to Knoxville?

    Airlines like Delta fly from San Antonio to Knoxville in about 6h 26m. The time it takes to get you to your destination can typically vary by up to . The distance between San Antonio and Knoxville is about 945 mi.

  • What are the cheapest airlines flying from San Antonio to Knoxville round-trip?

    Our cheapest airline available from San Antonio to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $144 on this airline. Additional options worth looking into are American Airlines and United Airlines, starting at $216 and $258 round-trip. You may be able to fly from San Antonio to Knoxville for 58% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Antonio to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Antonio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Knoxville.

  • Can I find deals for business class flights from San Antonio to Knoxville?

    Yes. Cheapflights offers flight deals from San Antonio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Knoxville?

    Currently, September is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $79). Flying from San Antonio to Knoxville in January is currently the most expensive (average of $125). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for San Antonio to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Hobby to Nashville flights
Dallas/Fort Worth to Nashville flights
George Bush Intcntl to Nashville flights
George Bush Intcntl to Knoxville flights
Dallas/Fort Worth to Memphis flights
Dallas/Fort Worth to Knoxville flights
Austin to Nashville flights
Hobby to Knoxville flights
Love Field to Nashville flights
Hobby to Memphis flights
Love Field to Memphis flights
San Antonio to Nashville flights
George Bush Intcntl to Memphis flights
Dallas/Fort Worth to Chattanooga flights
Dallas/Fort Worth to Blountville flights
Austin to Knoxville flights
Austin to Chattanooga flights
Love Field to Knoxville flights
Austin to Memphis flights
El Paso to Nashville flights
San Antonio to Memphis flights
Hobby to Blountville flights
Hobby to Chattanooga flights
George Bush Intcntl to Chattanooga flights
George Bush Intcntl to Blountville flights
El Paso to Knoxville flights
Brownsville to Nashville flights
Midland to Nashville flights
McAllen to Nashville flights
Love Field to Chattanooga flights
Austin to Blountville flights
Love Field to Blountville flights
Corpus Christi to Nashville flights
Corpus Christi to Knoxville flights
Harlingen to Nashville flights
Lubbock to Nashville flights
Midland to Knoxville flights
Amarillo to Nashville flights
Texarkana to Chattanooga flights
Amarillo to Knoxville flights
Laredo to Nashville flights
San Antonio to Blountville flights
Corpus Christi to Memphis flights
College Station to Nashville flights
Killeen to Blountville flights
Lubbock to Chattanooga flights
Waco to Nashville flights
El Paso to Chattanooga flights
McAllen to Knoxville flights

Top 3 airlines flying from San Antonio to Knoxville

Discover the top 3 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated November 13, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$144Average$325FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$216Average$371FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$374FlexibilityNo cancel feeOn-time69%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.