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$125+ Cheap flights from San Antonio to Knoxville (SAT - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/15. Fares are subject to change and may not be available on all flights or dates of travel.
SAT — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from San Antonio to Knoxville McGhee Tyson are usually found in January or September, booked 73 days in advance, depart on a Wednesday or Tuesday and return on a Friday

Cheap flight deals from San Antonio to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from San Antonio (SAT) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$217
(American Airlines)

One-way from

$125
(Delta)

Popular in

March

Cheapest in

January

Average price

$358
From San Antonio to Knoxville McGhee Tyson
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One-way flight from San Antonio to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 10% potential increase in price ($40 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($12 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from San Antonio to Knoxville

Cheapest flights from San Antonio to Knoxville
Explore the most affordable flight options available from San Antonio to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This American Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/308:04 amSAT - TYS
1 stop5h 18mAmerican Airlines
Tue 8/55:19 pmTYS - SAT
1 stop6h 19mAmerican Airlines
Deal found 6/10$217
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/17:10 amSAT - TYS
1 stop27h 52mMultiple Airlines
Sun 8/33:11 pmTYS - SAT
1 stop10h 23mMultiple Airlines
Deal found 6/10$248
This Delta deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2112:50 pmSAT - TYS
1 stop7h 42mDelta
Thu 10/237:15 pmTYS - SAT
1 stop6h 10mDelta
Deal found 6/12$249
This United Airlines deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/3012:55 pmSAT - TYS
1 stop8h 40mUnited Airlines
Tue 8/57:00 amTYS - SAT
2 stops11h 42mUnited Airlines
Deal found 6/10$397
This Alaska Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Alaska Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/116:30 amSAT - TYS
2 stops16h 21mAlaska Airlines
Sun 9/146:00 amTYS - SAT
2 stops18h 59mAlaska Airlines
Deal found 6/12$1,079

Cheapflights Fare Finder

Customize your flight search to find flights from San Antonio to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from San Antonio to Knoxville that are best for you.

Fly from

San Antonio

Fly to

Knoxville

Route

Depart

Return

Price

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 7/30

8:04 am-2:22 pm

1 stop5h 18m

Knoxville McGhee Tyson

Tue 8/5

5:19 pm-10:38 pm

1 stop6h 19m

$217

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Fri 8/1

7:10 am-12:02 pm

1 stop27h 52m

Knoxville McGhee Tyson

Sun 8/3

3:11 pm-12:34 am

1 stop10h 23m

$248

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 7/9

5:25 am-11:08 am

1 stop4h 43m

Knoxville McGhee Tyson

Thu 7/10

7:50 am-3:31 pm

1 stop8h 41m

$249

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Mon 7/7

5:56 pm-11:27 pm

1 stop4h 31m

Knoxville McGhee Tyson

Mon 7/14

7:00 am-11:45 am

1 stop5h 45m

$269

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Thu 9/18

6:30 am-11:51 pm

2 stops16h 21m

Knoxville McGhee Tyson

Sun 9/21

6:00 am-11:59 pm

2 stops18h 59m

$1,079

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Tue 7/15

12:24 pm-7:01 pm

1 stop5h 37m

$125

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Sat 7/26

7:52 pm-8:04 pm

2 stops23h 12m

$161

San AntonioKnoxville

SAT - TYS

SATTYS

San Antonio

Wed 6/18

5:30 am-4:57 pm

2 stops10h 27m

$551

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from San Antonio to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from San Antonio with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from San Antonio to Knoxville

How far ahead should I book a flight from San Antonio to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from San Antonio to Knoxville. Price data was last updated on June 9, 2025.

Booking 73 days in advance of your planned departure date is, on average, the best time to get cheap flights from San Antonio to Knoxville. The general trend is that the closer you book to the departure date, the more expensive your flight will be.

What is the cheapest month to book a flight from San Antonio to Knoxville?

Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $296). Flying from San Antonio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from SAT to TYS?

Find hourly flight availability from San Antonio to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

A simple way to save on the total cost of your ticket is to fly from San Antonio to Knoxville in the evening. If you’re flexible enough to do this you can expect to save up to 26% on your trip compared to booking a flight in the morning.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
See what other customers who have flown with Alaska Airlines, Delta and United Airlines from San Antonio to Knoxville have to say. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Alaska Airlines
8.0
Very good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
Delta
8.0
Very good
7,946 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
United Airlines
7.4
Good
8,790 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.
American Airlines
7.2
Good
10,000 reviews
Alaska Airlines
8.0
Very good
10,000 reviews

Boarding

8.1

Comfort

7.8

Entertainment

7.1

Overall

8.0

Food

7.1

Crew

8.5

Reviews

1 / 20
10.0
Excellent

James,Apr 2025

LAX - SFO

Good flight except the uncontrollable cold air from the ceiling.

Related info for your journey

Find useful and relevant information for your journey from San Antonio to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from San Antonio to Knoxville round-trip?

    Our cheapest airline available from San Antonio to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $217 on this airline. Additional options worth looking into are Delta and United Airlines, starting at $249 and $379 round-trip. You may be able to fly from San Antonio to Knoxville for 38% less than the average price by searching for these airlines.

  • Can I find deals for flights from San Antonio to Knoxville that include hotel bookings?

    Yes. In addition to deals on San Antonio to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from San Antonio to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from San Antonio to Knoxville.

  • Can I find deals for business class flights from San Antonio to Knoxville?

    Yes. Cheapflights offers flight deals from San Antonio to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from San Antonio to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from San Antonio to Knoxville (average of $296). Flying from San Antonio to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near San Antonio?

Book flights to San Antonio if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Alternative routes for San Antonio to Knoxville

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Top 3 airlines flying from San Antonio to Knoxville

Discover the top 3 airlines that operate flights from San Antonio to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$236Average$336FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$248Average$360FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$258Average$407FlexibilityNo cancel feeOn-time69%

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