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Knoxville

$130+ Cheap flights from Milwaukee to Knoxville (MKE - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/2. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — TYS
ene. 11 — ene. 181
dom. 1/11
dom. 1/18
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Knoxville McGhee Tyson are usually found in January or February, booked 57 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Milwaukee to Knoxville

Cheapest flights from Milwaukee to Knoxville
Explore the most affordable flight options available from Milwaukee to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on diciembre 12, 2025.

This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1710:54 amMKE - TYS
1 stop5h 17mUnited Airlines
sáb. 12/205:35 pmTYS - MKE
1 stop4h 36mUnited Airlines
Deal found 12/10$299
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/176:01 amMKE - TYS
2 stops6h 59mAmerican Airlines
sáb. 12/204:29 pmTYS - MKE
1 stop6h 31mAmerican Airlines
Deal found 12/10$304
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/317:45 amMKE - TYS
1 stop7h 11mAmerican Airlines
dom. 1/45:42 amTYS - MKE
1 stop5h 43mAmerican Airlines
Deal found 12/10$322
This American Airlines deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/187:45 amMKE - TYS
2 stops7h 59mAmerican Airlines
lun. 12/224:29 pmTYS - MKE
1 stop6h 31mAmerican Airlines
Deal found 12/9$334
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/297:45 amMKE - TYS
1 stop12h 44mAmerican Airlines
vie. 1/25:42 amTYS - MKE
1 stop5h 43mAmerican Airlines
Deal found 12/11$343
This American Airlines deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/123:45 pmMKE - TYS
1 stop4h 37mAmerican Airlines
jue. 12/181:24 pmTYS - MKE
1 stop5h 18mAmerican Airlines
Deal found 12/11$344
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/256:00 amMKE - TYS
2 stops9h 38mAmerican Airlines
mié. 12/314:28 pmTYS - MKE
1 stop6h 03mAmerican Airlines
Deal found 12/10$348
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/253:48 pmMKE - TYS
1 stop5h 51mUnited Airlines
mié. 12/316:45 amTYS - MKE
1 stop5h 42mUnited Airlines
Deal found 12/10$367
This Delta deal was found by Cheapflights users on 12/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/117:00 amMKE - TYS
1 stop6h 52mDelta
dom. 12/145:40 amTYS - MKE
1 stop4h 48mDelta
Deal found 12/9$389
This United Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 12/253:48 pmMKE - TYS
1 stop5h 51mUnited Airlines
mar. 12/305:35 pmTYS - MKE
1 stop5h 38mUnited Airlines
Deal found 12/10$393
This American Airlines deal was found by Cheapflights users on 12/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 12/155:00 amMKE - TYS
2 stops8h 00mAmerican Airlines
jue. 12/1810:49 amTYS - MKE
1 stop6h 41mAmerican Airlines
Deal found 12/10$394
This Delta deal was found by Cheapflights users on 12/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
vie. 12/125:45 amMKE - TYS
1 stop6h 59mDelta
dom. 12/145:40 amTYS - MKE
1 stop6h 06mDelta
Deal found 12/11$399

Find flight deals from Milwaukee to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated diciembre 12, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$209
(American Airlines)

One-way from

$195
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$338
Provider with most accurate pricing for Milwaukee-Mitchell-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Milwaukee-Mitchell-Knoxville McGhee Tyson flights.
Search Deals
From Milwaukee-Mitchell to Knoxville McGhee Tyson
Search Deals
One-way flight from Milwaukee-Mitchell to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 0% potential increase in price ($2 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 1% potential price decrease ($6 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

Fly from

Milwaukee

Fly to

Knoxville

Route

Depart

Return

Price

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

vie. 1/23

4:05 pm-9:21 pm

1 stop4h 16m

Knoxville McGhee Tyson

lun. 1/26

7:11 pm-11:35 pm

1 stop5h 24m

$209

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

mar. 2/24

6:29 pm-11:52 pm

1 stop4h 23m

Knoxville McGhee Tyson

mar. 5/5

5:30 am-9:22 am

1 stop4h 52m

$209

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

mié. 1/7

7:32 am-3:20 pm

2 stops6h 48m

Knoxville McGhee Tyson

lun. 1/26

6:00 am-11:17 am

1 stop6h 17m

$214

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

mar. 2/24

8:42 am-5:31 pm

2 stops7h 49m

Knoxville McGhee Tyson

mar. 5/5

7:22 am-11:43 am

1 stop5h 21m

$214

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

jue. 2/19

6:22 am-3:40 pm

1 stop8h 18m

Knoxville McGhee Tyson

dom. 2/22

4:30 pm-10:04 pm

1 stop6h 34m

$253

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

jue. 4/2

4:20 pm-10:10 pm

1 stop4h 50m

$130

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

dom. 12/28

8:06 pm-9:48 pm

1 stop24h 42m

$220

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

lun. 12/29

8:15 pm-11:32 pm

2 stops26h 17m

$321

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

dom. 12/28

7:45 am-9:58 pm

2 stops13h 13m

$434

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

jue. 4/2

6:00 am-6:20 pm

3 stops35h 20m

$2,580

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/11

Compare providers for flights from Milwaukee to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Milwaukee to Knoxville in December.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Milwaukee-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Milwaukee-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Milwaukee-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Milwaukee-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Milwaukee-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Milwaukee to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Knoxville

How far ahead should I book a flight from Milwaukee to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Knoxville. Price data was last updated on December 5, 2025.

The best time to book flights from Milwaukee to Knoxville is 12 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Milwaukee to Knoxville?

Currently, June is the cheapest month in which you can book a flight from Milwaukee to Knoxville (average of $62). Flying from Milwaukee to Knoxville in December is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Milwaukee to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated diciembre 12, 2025.
Read through reviews of airlines operating flights from Milwaukee to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
Delta
7.9
Good
8,007 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
United Airlines
7.4
Good
9,095 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.
American Airlines
7.2
Good
11,050 reviews
Delta
7.9
Good
8,007 reviews

Boarding

8.1

Overall

7.9

Comfort

7.9

Crew

8.5

Food

7.3

Entertainment

7.9

Reviews

1 / 20
6.0
Good

Jim,Nov 2025

AVL - ATL

The exit row seats without a seat in front are great for leg room but don’t have a fold out entertainment console so you’re forced to use the screen several feet in front of you (there is, at least, a remote). Best to bring a tablet loaded with entertainment or a book.

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Knoxville?

    American Airlines and Delta can get you from Milwaukee to Knoxville in just under 4h 16m. Your travel time can differ by up to 07m. The distance from Milwaukee to Knoxville is about 535 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Milwaukee to Knoxville round-trip?

    Currently priced at $198, Delta will fly you from Milwaukee to Knoxville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $208 and $209, respectively. These flights start at 35% lower than the current average price 3 months from now.

  • Can I find deals for flights from Milwaukee to Knoxville that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Knoxville.

  • Can I find deals for business class flights from Milwaukee to Knoxville?

    Yes. Cheapflights offers flight deals from Milwaukee to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Knoxville?

    Currently, June is the cheapest month in which you can book a flight from Milwaukee to Knoxville (average of $62). Flying from Milwaukee to Knoxville in December is currently the most expensive (average of $193). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Milwaukee to Knoxville

Discover the top 3 airlines that operate flights from Milwaukee to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated diciembre 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$290FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$305FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$209Average$308FlexibilityNo cancel feeOn-time69%

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