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$154+ Cheap flights from Milwaukee to Knoxville (MKE - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/3. Fares are subject to change and may not be available on all flights or dates of travel.
MKE — TYS
Oct 11 — Oct 181
Sat 10/11
Sat 10/18
1 adult, Economy
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Cheapflights Tip: The best prices from Milwaukee-Mitchell to Knoxville McGhee Tyson are usually found in January or February, booked 39 days in advance, depart on a Wednesday or Saturday and return on a Tuesday

Cheap flight deals from Milwaukee to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Milwaukee (MKE) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 11, 2025.

Round-trip from

$193
(United Airlines)

One-way from

$154
(American Airlines)

Popular in

March

Cheapest in

January

Average price

$257
From Milwaukee-Mitchell to Knoxville McGhee Tyson
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One-way flight from Milwaukee-Mitchell to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($16 potential increase over avg. RT price).
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Cheapest flight prices on average. 2% potential price decrease ($6 potential savings vs. average RT price).
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Average for round-trip flights in September 2025
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Find flight deals from Milwaukee to Knoxville

Cheapest flights from Milwaukee to Knoxville
Explore the most affordable flight options available from Milwaukee to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 11, 2025.

This United Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/85:45 pmMKE - TYS
1 stop4h 05mUnited Airlines
Wed 10/157:00 amTYS - MKE
1 stop4h 11mUnited Airlines
Deal found 9/10$193
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/83:25 pmMKE - TYS
1 stop7h 43mAmerican Airlines
Tue 11/1112:46 pmTYS - MKE
2 stops7h 28mAmerican Airlines
Deal found 9/10$198
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/33:47 pmMKE - TYS
1 stop6h 16mAmerican Airlines
Wed 10/87:00 amTYS - MKE
1 stop5h 49mAmerican Airlines
Deal found 9/11$201
This American Airlines deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/262:12 pmMKE - TYS
1 stop6h 07mAmerican Airlines
Tue 9/307:18 amTYS - MKE
1 stop5h 40mAmerican Airlines
Deal found 9/11$206
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/245:46 pmMKE - TYS
1 stop5h 35mAmerican Airlines
Mon 9/297:45 pmTYS - MKE
1 stop4h 15mAmerican Airlines
Deal found 9/8$214
This Delta deal was found by Cheapflights users on 9/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/197:11 amMKE - TYS
1 stop5h 31mDelta
Mon 10/278:10 pmTYS - MKE
1 stop4h 45mDelta
Deal found 9/11$217
This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/256:15 amMKE - TYS
1 stop5h 54mAmerican Airlines
Sun 9/288:36 pmTYS - MKE
1 stop4h 33mAmerican Airlines
Deal found 9/8$219
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/272:23 pmMKE - TYS
2 stops7h 40mAmerican Airlines
Mon 9/297:45 pmTYS - MKE
1 stop4h 15mAmerican Airlines
Deal found 9/9$224
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/32:45 pmMKE - TYS
1 stop7h 18mAmerican Airlines
Fri 10/108:37 pmTYS - MKE
1 stop4h 37mAmerican Airlines
Deal found 9/9$249
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/166:44 pmMKE - TYS
1 stop4h 02mDelta
Sun 10/198:35 pmTYS - MKE
1 stop4h 20mDelta
Deal found 9/9$259

Cheapflights Fare Finder

 
Customize your flight search to find flights from Milwaukee to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
Use the filters below to find and compare flights from Milwaukee to Knoxville that are best for you.

Fly from

Milwaukee

Fly to

Knoxville

Route

Depart

Return

Price

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 10/8

5:45 pm-10:50 pm

1 stop4h 05m

Knoxville McGhee Tyson

Wed 10/15

7:00 am-10:11 am

1 stop4h 11m

$193

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Sat 11/8

12:05 pm-5:08 pm

1 stop4h 03m

Knoxville McGhee Tyson

Tue 11/11

1:52 pm-5:17 pm

1 stop4h 25m

$193

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 10/3

3:47 pm-11:03 pm

1 stop6h 16m

Knoxville McGhee Tyson

Wed 10/8

7:00 am-11:49 am

1 stop5h 49m

$201

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Mon 11/10

6:29 am-11:31 am

1 stop4h 02m

Knoxville McGhee Tyson

Tue 11/18

7:59 am-11:38 am

1 stop4h 39m

$201

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Sat 10/4

10:50 am-5:17 pm

1 stop5h 27m

Knoxville McGhee Tyson

Sun 10/5

5:53 pm-8:46 pm

1 stop3h 53m

$201

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Wed 9/24

5:46 pm-12:21 am

1 stop5h 35m

Knoxville McGhee Tyson

Mon 9/29

7:45 pm-11:00 pm

1 stop4h 15m

$214

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Thu 9/25

6:15 am-1:09 pm

1 stop5h 54m

Knoxville McGhee Tyson

Mon 9/29

7:45 pm-11:00 pm

1 stop4h 15m

$214

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Tue 2/24

2:00 pm-8:36 pm

1 stop5h 36m

Knoxville McGhee Tyson

Tue 5/5

7:30 am-12:26 pm

1 stop5h 56m

$217

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Sun 10/19

7:11 am-1:42 pm

1 stop5h 31m

Knoxville McGhee Tyson

Mon 10/27

8:10 pm-11:55 pm

1 stop4h 45m

$217

MilwaukeeKnoxville

MKE - TYS

MKETYS

Milwaukee-Mitchell

Fri 10/3

2:45 pm-11:03 pm

1 stop7h 18m

$154

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/11

Showing 1-10 of 15 results
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Best time to book a flight from Milwaukee to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Milwaukee with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Milwaukee to Knoxville

How far ahead should I book a flight from Milwaukee to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Milwaukee to Knoxville. Price data was last updated on August 29, 2025.

The best time to book flights from Milwaukee to Knoxville is 39 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Milwaukee to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Milwaukee to Knoxville (average of $294). Flying from Milwaukee to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 11, 2025.
Read through reviews of airlines operating flights from Milwaukee to Knoxville, such as Delta, United Airlines, and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
United Airlines
7.4
Good
8,937 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Boarding

8.2

Crew

8.5

Entertainment

7.9

Overall

8.0

Comfort

7.9

Food

7.3

Reviews

1 / 20
10.0
Excellent

Kim,May 2025

PIH - SLC

This trip was fine even with delay I had plenty of time to get connection flight!

Related info for your journey

Find useful and relevant information for your journey from Milwaukee to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Milwaukee to Knoxville?

    United Airlines and American Airlines can get you from Milwaukee to Knoxville in just under 4h 05m. Your travel time can differ by up to 2h 11m. The distance from Milwaukee to Knoxville is about 535 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Milwaukee to Knoxville round-trip?

    Currently priced at $198, Delta will fly you from Milwaukee to Knoxville and back. In addition to Delta, many other airlines offer competitively priced options for your trip. Search Cheapflights for deals from American Airlines and United Airlines - these airlines can fly you to your destination from $208 and $213, respectively. These flights start at 34% lower than the current average price 3 months from now.

  • What are the cheapest airlines to fly from Milwaukee to Knoxville one-way?

    The cheapest airline one-way is American Airlines, with whom users have recently found tickets for as low as $154. However, be on the lookout for offers from Delta and United Airlines, as they are both options that can get you from Milwaukee to Knoxville for a low price.

  • Can I find deals for flights from Milwaukee to Knoxville that include hotel bookings?

    Yes. In addition to deals on Milwaukee to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Milwaukee to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Milwaukee to Knoxville.

  • Can I find deals for business class flights from Milwaukee to Knoxville?

    Yes. Cheapflights offers flight deals from Milwaukee to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Milwaukee to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Milwaukee to Knoxville (average of $294). Flying from Milwaukee to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Milwaukee to Knoxville

Discover the top 3 airlines that operate flights from Milwaukee to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated September 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$198Average$272FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$208Average$310FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$213Average$343FlexibilityNo cancel feeOn-time69%

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