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Knoxville

$146+ Cheap flights from Madison to Knoxville (MSN - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/20. Fares are subject to change and may not be available on all flights or dates of travel.
MSN — TYS
May 23 — May 301
Sat 5/23
Sat 5/30
1 adult, Economy
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Cheap flight deals from Madison to Knoxville

Cheapest flights from Madison to Knoxville
Explore the most affordable flight options available from Madison to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 23, 2026.

This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/285:00 am
MSN
-
TYS
1 stop4h 59m
American Airlines
Sat 5/305:33 pm
TYS
-
MSN
1 stop6h 33m
American Airlines
Deal found 4/19$285
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/1611:35 am
MSN
-
TYS
1 stop4h 32m
American Airlines
Sat 5/235:36 am
TYS
-
MSN
1 stop6h 02m
American Airlines
Deal found 4/22$288
This Delta deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/145:17 pm
MSN
-
TYS
1 stop5h 30m
Delta
Sat 8/225:30 am
TYS
-
MSN
1 stop5h 41m
Delta
Deal found 4/20$307
This American Airlines deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/161:05 pm
MSN
-
TYS
1 stop7h 52m
American Airlines
Thu 5/216:00 am
TYS
-
MSN
1 stop7h 55m
American Airlines
Deal found 4/22$310
This Kiwi.com deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:55 pm
MSN
-
TYS
1 stop15h 29m
Multiple Airlines
Fri 5/2210:03 pm
TYS
-
MSN
1 stop22h 12m
Multiple Airlines
Deal found 4/22$311
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/165:29 pm
MSN
-
TYS
1 stop5h 27m
Delta
Sat 5/235:35 pm
TYS
-
MSN
1 stop4h 24m
Delta
Deal found 4/22$325
This American Airlines deal was found by Cheapflights users on 4/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/311:10 am
MSN
-
TYS
1 stop4h 28m
American Airlines
Sat 11/74:27 pm
TYS
-
MSN
1 stop6h 27m
American Airlines
Deal found 4/21$329
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/1412:39 pm
MSN
-
TYS
1 stop7h 54m
American Airlines
Sat 8/226:00 am
TYS
-
MSN
1 stop5h 40m
American Airlines
Deal found 4/19$332
This American Airlines deal was found by Cheapflights users on 4/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/81:05 pm
MSN
-
TYS
1 stop7h 52m
American Airlines
Sun 5/106:00 am
TYS
-
MSN
1 stop6h 14m
American Airlines
Deal found 4/19$334
This United Airlines deal was found by Cheapflights users on 4/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/52:30 pm
MSN
-
TYS
1 stop5h 15m
United Airlines
Sat 5/95:55 pm
TYS
-
MSN
1 stop4h 25m
United Airlines
Deal found 4/20$339
This Delta deal was found by Cheapflights users on 4/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/175:43 am
MSN
-
TYS
1 stop4h 26m
Delta
Sat 5/235:35 pm
TYS
-
MSN
1 stop4h 24m
Delta
Deal found 4/22$344

Find flight deals from Madison to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Madison (MSN) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 23, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$285
(American Airlines)

One-way from

$146
(American Airlines)

Popular in

February

Cheapest in

May

Average price

$339
Provider with most accurate pricing for Madison Truax Field-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Madison Truax Field-Knoxville McGhee Tyson flights.
Search Deals
From Madison Truax Field to Knoxville McGhee Tyson
Search Deals
One-way flight from Madison Truax Field to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 9% potential increase in price ($38 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in April 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Madison to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
Use the filters below to find and compare flights from Madison to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Fri 8/14

5:17 pm-11:47 pm

1 stop5h 30m

Knoxville McGhee Tyson

Sat 8/22

5:30 am-10:11 am

1 stop5h 41m

$307

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Thu 5/21

5:43 am-11:09 am

1 stop4h 26m

Knoxville McGhee Tyson

Thu 5/28

7:51 am-12:41 pm

1 stop5h 50m

$349
Quickest round-trip

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 5/26

3:53 pm-8:56 pm

1 stop4h 03m

Knoxville McGhee Tyson

Sat 5/30

6:02 pm-8:54 pm

1 stop3h 52m

$365

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sat 5/16

2:25 pm-8:47 pm

1 stop5h 22m

Knoxville McGhee Tyson

Wed 5/20

7:00 am-10:12 am

1 stop4h 12m

$371

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Tue 5/19

2:30 pm-8:45 pm

1 stop5h 15m

Knoxville McGhee Tyson

Sun 5/24

6:30 am-5:04 pm

2 stops11h 34m

$468

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sun 7/19

6:00 am-5:37 pm

2 stops10h 37m

Knoxville McGhee Tyson

Sat 7/25

6:07 pm-12:05 am

1 stop6h 58m

$487

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Fri 8/14

2:45 pm-8:48 pm

1 stop5h 03m

Knoxville McGhee Tyson

Sat 8/22

12:05 pm-10:42 pm

2 stops11h 37m

$487

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Sun 5/3

10:50 am-4:59 pm

1 stop5h 09m

Knoxville McGhee Tyson

Thu 5/7

6:01 pm-10:54 pm

1 stop5h 53m

$539
Cheapest one-way

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Mon 8/3

4:36 pm-11:52 pm

1 stop6h 16m

$185

MadisonKnoxville

MSN - TYS

MSNTYS

Madison Truax Field

Fri 5/8

1:05 pm-9:57 pm

1 stop7h 52m

$200

Flights are sorted by cheapest round-trip flights first.

Deals found on 4/17

Showing 1-10 of 19 resultsSorted by cheapest first
1
2

Compare providers for flights from Madison to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Madison to Knoxville in April.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Madison-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Madison-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Madison-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Madison-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Madison-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Madison to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Madison with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Madison to Knoxville

What is the cheapest month to book a flight from Madison to Knoxville?

Currently, May is the cheapest month in which you can book a flight from Madison to Knoxville (average of $298). Flying from Madison to Knoxville in February is currently the most expensive (average of $533). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

How much does it cost to fly round-trip from Madison to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 23, 2026.
Read through reviews of airlines operating flights from Madison to Knoxville, such as American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
American Airlines
7.1
Good
11,659 reviews

Overall

7.1

Comfort

7.2

Crew

7.9

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.
American Airlines
7.1
Good
11,659 reviews
American Airlines
7.1
Good
11,659 reviews

Overall

7.1

Comfort

7.2

Crew

7.9

Boarding

7.5

Entertainment

6.9

Food

6.4

Reviews

1 / 20
4.0
Okay

Elizabeth,Mar 2026

ORD - MIA

Staff was rude and flight attendants 2 out of 3 looked like they had just been thru a hurricane.

Related info for your journey

Find useful and relevant information for your journey from Madison to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Madison to Knoxville?

    Airlines like Delta and United Airlines fly from Madison to Knoxville in about 4h 03m. The time it takes to get you to your destination can typically vary by up to 1h 27m. Airlines will cover a distance of 580 mi. This flight may include one or multiple stops.

  • What is the cheapest airline to fly from Madison to Knoxville round-trip?

    Currently priced at $248, American Airlines will fly you from Madison to Knoxville and back. In addition to American Airlines, many other airlines offer competitively priced options for your trip. This flight start at 34% lower than the current average price 3 months from now.

  • Can I find deals for flights from Madison to Knoxville that include hotel bookings?

    Yes. In addition to deals on Madison to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Madison to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Madison to Knoxville.

  • Can I find deals for business class flights from Madison to Knoxville?

    Yes. Cheapflights offers flight deals from Madison to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Madison to Knoxville?

    Currently, May is the cheapest month in which you can book a flight from Madison to Knoxville (average of $298). Flying from Madison to Knoxville in February is currently the most expensive (average of $533). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

Browse thousands of different options on Cheapflights for your next trip

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Top airline flying from Madison to Knoxville

Discover the top airline that operate flights from Madison to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 23, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$248Average$384FlexibilityNo cancel feeOn-time71%

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