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Knoxville

$81+ Cheap flights from Michigan to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/15. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Jan 17 — Jan 241
Sat 1/17
Sat 1/24
1 adult, Economy
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Cheap flight deals from Michigan to Knoxville

Cheapest flights from Michigan to Knoxville
Explore the most affordable flight options available from Michigan to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 18, 2025.

This Delta deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/244:46 pmGRR - TYS
1 stop6h 47mDelta
Thu 12/254:54 pmTYS - GRR
1 stop6h 39mDelta
Deal found 12/17$223
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:38 pmORD - TYS
1 stop18h 22mMultiple Airlines
Thu 1/81:39 pmTYS - ORD
1 stop8h 52mMultiple Airlines
Deal found 12/17$229
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/311:11 pmORD - TYS
Nonstop1h 45mAmerican Airlines
Fri 1/25:42 amTYS - ORD
1 stop5h 21mAmerican Airlines
Deal found 12/16$259
This United Airlines deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/312:07 pmORD - TYS
Nonstop1h 53mUnited Airlines
Thu 1/86:45 amTYS - ORD
Nonstop2h 03mUnited Airlines
Deal found 12/17$264
This American Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/2511:07 amORD - TYS
1 stop6h 00mAmerican Airlines
Mon 12/295:08 pmTYS - ORD
Nonstop2h 12mAmerican Airlines
Deal found 12/15$269
This Mytrip deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/319:28 pmDTW - TYS
1 stop14h 32mMultiple Airlines
Tue 1/67:22 pmTYS - DTW
2 stops12h 45mMultiple Airlines
Deal found 12/17$272
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 12/201:54 pmORD - TYS
1 stop7h 04mAmerican Airlines
Wed 12/312:58 pmTYS - ORD
Nonstop2h 10mAmerican Airlines
Deal found 12/16$274
This Kiwi.com deal was found by Cheapflights users on 12/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/314:38 pmORD - TYS
1 stop18h 22mMultiple Airlines
Wed 1/73:53 pmTYS - ORD
2 stops20h 42mMultiple Airlines
Deal found 12/17$289
This Frontier deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:00 amORD - TYS
1 stop7h 31mFrontier
Tue 12/304:46 pmTYS - ORD
1 stop8h 26mFrontier
Deal found 12/16$293
This United Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/177:30 amORD - TYS
Nonstop1h 43mUnited Airlines
Tue 12/236:45 amTYS - ORD
Nonstop2h 07mUnited Airlines
Deal found 12/16$294
This American Airlines deal was found by Cheapflights users on 12/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/175:00 amORD - TYS
1 stop5h 32mAmerican Airlines
Tue 12/237:48 amTYS - ORD
Nonstop2h 02mAmerican Airlines
Deal found 12/16$304
This United Airlines deal was found by Cheapflights users on 12/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/257:48 pmORD - TYS
Nonstop1h 51mUnited Airlines
Mon 12/2911:00 amTYS - ORD
Nonstop1h 58mUnited Airlines
Deal found 12/15$305

Find flight deals from Michigan to Knoxville

Keep the following information in mind while searching for Michigan to Knoxville flight deals. Data was last updated December 18, 2025.

Most accurate provider

Mytrip
3 stars

Most trusted provider

Mytrip
3 stars

Round-trip from

$149
(Kiwi.com)

One-way from

$81
(Frontier)

Popular in

June

Cheapest in

April

Average price

$434

Good round-trip deal

$299 or less
Provider with most accurate pricing for Detroit (DTT)-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Detroit (DTT)-Knoxville McGhee Tyson flights.
Search Deals
From Michigan to Knoxville McGhee Tyson
Search Deals
One-way flight from Michigan to Knoxville McGhee Tyson
Search Deals
High demand for flights, 0% potential price rise
Search Deals
Cheapest flight prices on average. 2% potential price decrease ($10 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in December 2025
Search Deals
Price to beat on a round-trip flight from Michigan to Knoxville McGhee Tyson.
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Michigan to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
Use the filters below to find and compare flights from Michigan to Knoxville that are best for you.

Fly from

Michigan

Fly to

Knoxville

Route

Depart

Return

Price

South BendKnoxville

SBN - TYS

SBNTYS

South Bend/Michiana

Sat 1/17

6:00 am-10:32 am

1 stop4h 32m

Knoxville McGhee Tyson

Tue 1/20

11:10 am-5:44 pm

1 stop6h 34m

$177

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/6

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 2/8

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/30

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 2/2

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/9

10:35 am-1:24 pm

Nonstop1h 49m

Knoxville McGhee Tyson

Mon 1/12

5:29 pm-6:27 pm

Nonstop1h 58m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/30

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 2/1

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 1/9

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 1/11

6:45 am-7:48 am

Nonstop2h 03m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Fri 2/20

6:15 pm-8:57 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Mon 2/23

6:45 am-7:47 am

Nonstop2h 02m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 2/5

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sat 2/7

1:59 pm-2:55 pm

Nonstop1h 56m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/8

6:10 pm-8:52 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Tue 1/13

5:29 pm-6:27 pm

Nonstop1h 58m

$189

ChicagoKnoxville

ORD - TYS

ORDTYS

Chicago O'Hare Intl

Thu 1/8

8:43 pm-1:40 pm

1 stop15h 57m

Knoxville McGhee Tyson

Mon 1/12

12:55 pm-1:13 pm

1 stop25h 18m

$205

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/17

Showing 1-10 of 60 results
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Best time to book a flight from Michigan to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Michigan with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Michigan to Knoxville

What is the cheapest month to book a flight from Michigan to Knoxville?

Currently, July is the cheapest month in which you can book a flight from Michigan to Knoxville (average of $160). Flying from Michigan to Knoxville in December is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from MI to TYS?

Find hourly flight availability from Michigan to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 18, 2025.

It’s typically best to fly out from Michigan to Knoxville at noon. Doing so could potentially save you 18% on the flight price compared to flying in the evening, which is usually more expensive.

What is the cheapest day to fly from Michigan to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Michigan to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Michigan to Knoxville flight should consider departing on Tuesday evenings when fares are most often at their lowest. Sunday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

Related info for your journey

Find useful and relevant information for your journey from Michigan to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly into for flights to Knoxville from Michigan?

    For a flight from Michigan to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city.

  • How long is the flight from Michigan to Knoxville?

    For as low as $177, United Airlines can have you in Knoxville from Michigan in 4h 32m. Michigan and Knoxville are separated by a distance of 426 mi. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What are the cheapest airlines to fly from Michigan to Knoxville one-way?

    One-way options have recently been found by users for as low as $99 on United Airlines. Other airlines that offer cheap prices include American Airlines from $99 and Delta from $125 one-way.

  • What are the most popular routes from Michigan to Knoxville?

    The most popular route from Michigan to Knoxville is Chicago O'Hare Intl - Knoxville McGhee Tyson. You may also consider Detroit Metropolitan Wayne County - Knoxville McGhee Tyson or Chicago Midway - Knoxville McGhee Tyson.

  • What are the most reliable airlines from Michigan to Knoxville?

    Before booking your flight to Knoxville from Michigan, check out the most reliable airlines to get you to your destination on time: Aeromexico (100%), Air France (96%), KLM( 78%).

  • What are the cheapest flights from Michigan to Knoxville?

    On average you can expect to pay $663 for a flight from Michigan to Knoxville. The cheapest flight overall is $299 while the most popular route, (Chicago O'Hare Intl - Knoxville McGhee Tyson) is currently priced at $189.

  • Can I find deals for flights from Michigan to Knoxville that include hotel bookings?

    Yes. In addition to deals on Michigan to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Michigan to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Michigan to Knoxville.

  • Can I find deals for business class flights from Michigan to Knoxville?

    Yes. Cheapflights offers flight deals from Michigan to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Michigan to Knoxville?

    Currently, July is the cheapest month in which you can book a flight from Michigan to Knoxville (average of $160). Flying from Michigan to Knoxville in December is currently the most expensive (average of $243). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 3 airlines flying from Michigan to Knoxville

Discover the top 3 airlines that operate flights from Michigan to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated December 18, 2025.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$192Average$377FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$198Average$347FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$346FlexibilityNo cancel feeOn-timeN/A

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