$101+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/12. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Jun 13 — Jun 201
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in October or March, booked 58 days in advance, depart on a Tuesday or Thursday and return on a Thursday
Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 14, 2026.
This Mytrip deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/318:00 am
DTW
- TYS
1 stop11h 36m
Frontier
Mon 8/38:32 pm
TYS
- DTW
1 stop16h 02m
Frontier
Deal found 5/11![Frontier logo]()
$239
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Fri 6/128:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/13![Frontier logo]()
$242
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Mon 6/88:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/11![Frontier logo]()
$256
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Wed 6/178:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/13![Frontier logo]()
$262
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Wed 6/108:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/13![Frontier logo]()
$267
This Kiwi.com deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/261:22 pm
DTW
- TYS
1 stop24h 27m
Multiple Airlines
Sun 8/3012:55 pm
TYS
- DTW
2 stops11h 47m
Multiple Airlines
Deal found 5/14![Multiple Airlines logo]()
$281
This Booking.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:55 am
DTW
- TYS
1 stop11h 29m
Frontier
Mon 6/18:32 pm
TYS
- DTW
1 stop16h 03m
Frontier
Deal found 5/12![Frontier logo]()
$282
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:50 pm
DTW
- TYS
1 stop5h 25m
Southwest
Tue 6/167:10 am
TYS
- DTW
1 stop5h 35m
Southwest
Deal found 5/10![Southwest logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:37 pm
DTW
- TYS
1 stop10h 56m
Multiple Airlines
Fri 8/712:50 pm
TYS
- DTW
2 stops24h 54m
Multiple Airlines
Deal found 5/11![Multiple Airlines logo]()
$303
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:40 am
DTW
- TYS
2 stops10h 20m
Southwest
Wed 6/178:10 am
TYS
- DTW
1 stop4h 25m
Southwest
Deal found 5/13![Southwest logo]()
$304
This Kiwi.com deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:02 pm
DTW
- TYS
2 stops26h 40m
Multiple Airlines
Mon 8/37:20 pm
TYS
- DTW
1 stop16h 35m
Multiple Airlines
Deal found 5/9![Multiple Airlines logo]()
$305
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 14, 2026.
This Delta deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/178:40 am
DTW
- TYS
Nonstop1h 47m
Delta
Wed 6/2411:41 am
TYS
- DTW
Nonstop1h 49m
Delta
Deal found 5/13![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:20 pm
DTW
- TYS
1 stop7h 30m
Southwest
Tue 6/96:55 pm
TYS
- DTW
1 stop3h 30m
Southwest
Deal found 5/13![Southwest logo]()
$343
This Delta deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:59 pm
DTW
- TYS
Nonstop1h 39m
Delta
Mon 8/35:22 pm
TYS
- DTW
Nonstop1h 46m
Delta
Deal found 5/10![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:25 pm
DTW
- TYS
2 stops7h 45m
Southwest
Mon 8/37:30 am
TYS
- DTW
2 stops13h 05m
Southwest
Deal found 5/9![Southwest logo]()
$367
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/281:39 pm
DTW
- TYS
Nonstop1h 39m
Delta
Sat 8/17:15 am
TYS
- DTW
Nonstop1h 46m
Delta
Deal found 5/9![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/512:25 pm
DTW
- TYS
1 stop4h 50m
Delta
Sat 7/116:00 am
TYS
- DTW
1 stop6h 56m
Delta
Deal found 5/12![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 5/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/307:20 am
DTW
- TYS
1 stop3h 45m
Delta
Mon 8/36:12 pm
TYS
- DTW
1 stop4h 21m
Delta
Deal found 5/9![Delta logo]()
$359
This Delta deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/157:59 pm
DTW
- TYS
Nonstop1h 39m
Delta
Sun 7/195:25 pm
TYS
- DTW
Nonstop1h 46m
Delta
Deal found 5/11![Delta logo]()
$399
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated May 14, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated May 14, 2026 and is based on user searches.
This Booking.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/297:55 am
DTW
- TYS
1 stop11h 29m
Frontier
Mon 6/18:32 pm
TYS
- DTW
1 stop16h 03m
Frontier
Deal found 5/12![Frontier logo]()
$282
This Southwest deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/212:40 pm
DTW
- TYS
2 stops8h 10m
Southwest
Thu 6/47:45 pm
TYS
- DTW
1 stop4h 20m
Southwest
Deal found 5/12![Southwest logo]()
$315
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/36:10 am
DTW
- TYS
2 stops11h 00m
Southwest
Tue 6/96:55 pm
TYS
- DTW
1 stop3h 30m
Southwest
Deal found 5/13![Southwest logo]()
$310
This Booking.com deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Mon 6/88:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/11![Frontier logo]()
$256
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Wed 6/108:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/13![Frontier logo]()
$267
This Southwest deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/93:50 pm
DTW
- TYS
1 stop5h 25m
Southwest
Tue 6/167:10 am
TYS
- DTW
1 stop5h 35m
Southwest
Deal found 5/10![Southwest logo]()
$299
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Fri 6/128:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 5/13![Frontier logo]()
$242
This Booking.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Booking.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/108:00 am
DTW
- TYS
1 stop11h 37m
Frontier
Wed 6/178:32 pm
TYS
- DTW
1 stop16h 14m
Frontier
Deal found 5/13![Frontier logo]()
$262
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:40 am
DTW
- TYS
2 stops10h 20m
Southwest
Wed 6/178:10 am
TYS
- DTW
1 stop4h 25m
Southwest
Deal found 5/13![Southwest logo]()
$304
This Southwest deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/106:40 am
DTW
- TYS
2 stops10h 20m
Southwest
Fri 6/127:45 pm
TYS
- DTW
1 stop4h 20m
Southwest
Deal found 5/13![Southwest logo]()
$323
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated May 14, 2026.
This Frontier deal was found by Cheapflights users on 5/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/128:00 am
DTW
- TYS
1 stop11h 36m
Frontier
Deal found 5/14![Frontier logo]()
$101
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/92:02 pm
DTW
- TYS
2 stops32h 22m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$107
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/108:00 am
DTW
- TYS
1 stop11h 36m
Frontier
Deal found 5/13![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/21:59 pm
DTW
- TYS
2 stops27h 59m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$113
This Frontier deal was found by Cheapflights users on 5/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/38:00 am
DTW
- TYS
1 stop11h 36m
Frontier
Deal found 5/11![Frontier logo]()
$121
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:00 am
DTW
- TYS
1 stop21h 32m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$129
This Frontier deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/78:00 am
DTW
- TYS
1 stop11h 36m
Frontier
Deal found 5/13![Frontier logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/96:54 pm
DTW
- TYS
2 stops23h 04m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 5/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/206:10 am
DTW
- TYS
2 stops15h 50m
Multiple Airlines
Deal found 5/10![Multiple Airlines logo]()
$133
This Kiwi.com deal was found by Cheapflights users on 5/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/41:59 pm
DTW
- TYS
2 stops31h 51m
Multiple Airlines
Deal found 5/12![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 5/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:10 am
DTW
- TYS
2 stops16h 14m
Multiple Airlines
Deal found 5/13![Multiple Airlines logo]()
$139
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated May 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $219 (Mytrip) |
One-way from | $101 (Frontier) |
Popular in | January |
Cheapest in | October |
Average price | $469 |
Good round-trip deal | $339 or less |
Good one-way deal | $248 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 6/17
8:40 am-10:27 am
Nonstop1h 47m
Knoxville McGhee Tyson
Wed 6/24
11:41 am-1:30 pm
Nonstop1h 49m
$339
Quickest round-trip
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Fri 7/31
7:59 pm-9:38 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Mon 8/3
5:22 pm-7:08 pm
Nonstop1h 46m
$339
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Tue 7/28
1:39 pm-3:18 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Sat 8/1
7:15 am-9:01 am
Nonstop1h 46m
$339
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 6/3
1:20 pm-8:50 pm
1 stop7h 30m
Knoxville McGhee Tyson
Tue 6/9
6:55 pm-10:25 pm
1 stop3h 30m
$343
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Sun 7/5
12:25 pm-5:15 pm
1 stop4h 50m
Knoxville McGhee Tyson
Sat 7/11
6:00 am-12:56 pm
1 stop6h 56m
$359
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 7/30
7:20 am-11:05 am
1 stop3h 45m
Knoxville McGhee Tyson
Mon 8/3
6:12 pm-10:33 pm
1 stop4h 21m
$359
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Thu 7/30
1:25 pm-9:10 pm
2 stops7h 45m
Knoxville McGhee Tyson
Mon 8/3
7:30 am-8:35 pm
2 stops13h 05m
$367
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 7/15
7:59 pm-9:38 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Sun 7/19
5:25 pm-7:11 pm
Nonstop1h 46m
$399
Cheapest one-way
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Wed 6/3
6:10 am-5:10 pm
2 stops11h 00m
$161
DetroitKnoxville
DTW - TYS
DTWTYS
Detroit Metropolitan Wayne County
Mon 6/15
8:00 am-7:37 pm
1 stop11h 37m
$166
Showing 1-10 of 17 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in May.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville
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How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 55 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Currently, October is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $388). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $713). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated May 14, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville at noon. If you’re flexible enough to do this you can expect to save up to 32% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated May 14, 2026.
Peruse reviews from past customers who have flown with Delta from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Crew
8.5
Comfort
7.8
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
10.0
ExcellentAnonymous,May 2026
SEA - KOA
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
Oak Ridge
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Top airline flying from Detroit to Knoxville
Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$423 | FlexibilityNo cancel fee | On-timeN/A |