$113+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 12/6. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Dec 10 — Dec 171
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in August or April, booked 80 days in advance, depart on a Thursday or Tuesday and return on a Thursday
Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Mon 12/79:49 pm -
1 stop21h 00m
Deal found 11/6![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:33 pm -
1 stop10h 54m
Mon 12/79:49 pm -
1 stop21h 00m
Deal found 11/6![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:29 pm -
1 stop19h 37m
Wed 11/186:17 pm -
1 stop29h 20m
Deal found 11/5![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Fri 12/119:49 pm -
1 stop15h 04m
Deal found 11/6![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Wed 12/911:02 am -
1 stop12h 23m
Deal found 11/6![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:33 pm -
1 stop15h 34m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Fri 12/119:37 pm -
1 stop25h 48m
Deal found 11/6![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Tue 12/81:57 pm -
1 stop21h 24m
Deal found 11/6![Multiple Airlines logo]()
$260
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated November 10, 2026.
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/188:30 am -
Nonstop1h 46m
Sun 12/207:25 am -
Nonstop1h 49m
Deal found 11/8![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/143:55 pm -
1 stop4h 55m
Tue 12/157:05 am -
1 stop6h 15m
Deal found 11/6![Southwest logo]()
$371
This United Airlines deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 12/17:50 pm -
1 stop4h 09m
Sat 12/55:35 pm -
1 stop6h 09m
Deal found 11/9![United Airlines logo]()
$389
This Delta deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:40 am -
Nonstop1h 47m
Sun 12/1311:49 am -
Nonstop1h 50m
Deal found 11/8![Delta logo]()
$369
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/44:43 pm -
Nonstop1h 39m
Sun 12/67:10 am -
Nonstop1h 49m
Deal found 11/6![Delta logo]()
$369
This Southwest deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/235:30 pm -
1 stop4h 15m
Fri 12/257:05 am -
2 stops13h 25m
Deal found 11/5![Southwest logo]()
$439
This Southwest deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/46:00 am -
2 stops10h 40m
Sun 12/67:05 am -
1 stop5h 40m
Deal found 11/6![Southwest logo]()
$463
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/247:49 pm -
Nonstop1h 40m
Sat 11/287:10 am -
Nonstop1h 50m
Deal found 11/9![Delta logo]()
$443
This Delta deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/137:49 pm -
Nonstop1h 40m
Sun 11/157:22 pm -
1 stop5h 35m
Deal found 11/6![Delta logo]()
$453
This Delta deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/188:25 am -
1 stop5h 30m
Sat 11/216:10 pm -
1 stop6h 47m
Deal found 11/10![Delta logo]()
$463
This Delta deal was found by Cheapflights users on 11/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/214:25 pm -
1 stop3h 44m
Tue 11/246:10 pm -
1 stop4h 02m
Deal found 11/9![Delta logo]()
$463
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated November 10, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated November 10, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 11/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:29 pm -
1 stop19h 37m
Wed 11/186:17 pm -
1 stop29h 20m
Deal found 11/5![Multiple Airlines logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Mon 12/79:49 pm -
1 stop21h 00m
Deal found 11/6![Multiple Airlines logo]()
$216
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$238
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Fri 12/119:37 pm -
1 stop25h 48m
Deal found 11/6![Multiple Airlines logo]()
$256
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/49:33 pm -
1 stop13h 04m
Tue 12/81:57 pm -
1 stop21h 24m
Deal found 11/6![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/69:33 pm -
1 stop10h 54m
Mon 12/79:49 pm -
1 stop21h 00m
Deal found 11/6![Multiple Airlines logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$245
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Fri 12/119:49 pm -
1 stop15h 04m
Deal found 11/6![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/68:05 pm -
1 stop17h 17m
Wed 12/911:02 am -
1 stop12h 23m
Deal found 11/6![Multiple Airlines logo]()
$253
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/79:33 pm -
1 stop15h 34m
Thu 12/109:05 pm -
1 stop26h 20m
Deal found 11/6![Multiple Airlines logo]()
$255
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated November 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/61:53 pm -
1 stop23h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/174:29 pm -
1 stop19h 37m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 11/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/164:29 pm -
1 stop24h 49m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/7![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 11/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/102:42 pm -
2 stops28h 00m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/8![Multiple Airlines logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 11/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 12/147:50 am -
1 stop12h 57m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/6![Multiple Airlines logo]()
$138
This Kiwi.com deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/57:55 pm -
1 stop15h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Multiple Airlines logo]()
$142
This Southwest deal was found by Cheapflights users on 11/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/512:45 pm -
2 stops9h 35m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 11/10![Southwest logo]()
$200
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated November 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $216 (Kiwi.com) |
One-way from | $113 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $467 |
Good round-trip deal | $447 or less |
Good one-way deal | $312 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Mon 12/14
7:50 am-8:47 pm
1 stop12h 57m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$138
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Thu 12/10
9:33 pm-8:27 am
1 stop10h 54m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$169
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Thu 12/24
8:50 am-8:50 pm
2 stops12h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$208
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 11/25
11:27 am-12:06 pm
1 stop24h 39m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$225
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Sun 11/22
5:00 am-10:40 am
1 stop5h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$232
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Tue 11/17
8:50 am-7:50 pm
2 stops11h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$237
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Thu 11/26
5:00 am-12:30 pm
1 stop7h 30m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$237
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Mon 11/23
11:27 am-10:06 pm
2 stops34h 39m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$237
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Fri 11/13
5:00 am-12:10 pm
2 stops7h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$237
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 11/25
5:40 am-12:05 pm
1 stop6h 25m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$259
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in November.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy2 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville
Prices
Airlines
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 77 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $341). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated November 10, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 8% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated November 10, 2026.
Peruse reviews from past customers who have flown with Delta from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Food
7.2
Boarding
8.1
Crew
8.5
Comfort
7.8
Overall
7.8
Entertainment
7.8
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Newport
Bryson City
Crossville
Morristown
Murphy
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Alternative routes for Detroit to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on November 10, 2026.
Detroit and Knoxville flights
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Other flights from Detroit
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Detroit to Knoxville
Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated November 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$437 | FlexibilityNo cancel fee | On-timeN/A |