$79+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/1. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Sep 8 — Sep 151
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in April or March, booked 24 days in advance, depart on a Tuesday or Thursday and return on a Thursday
Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:23 pm -
1 stop17h 41m
Fri 9/188:55 pm -
1 stop12h 52m
Deal found 8/4![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:23 pm -
1 stop17h 41m
Thu 9/171:19 pm -
2 stops11h 23m
Deal found 8/7![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:23 pm -
1 stop17h 41m
Fri 9/2510:54 am -
1 stop12h 33m
Deal found 8/5![Multiple Airlines logo]()
$203
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/212:56 pm -
1 stop10h 02m
Mon 10/59:28 pm -
1 stop14h 07m
Deal found 8/7![Multiple Airlines logo]()
$209
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:35 pm -
1 stop29h 05m
Wed 9/1610:54 am -
1 stop12h 33m
Deal found 8/7![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:57 pm -
1 stop15h 44m
Mon 9/217:04 pm -
1 stop15h 39m
Deal found 8/6![Multiple Airlines logo]()
$217
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 9, 2026.
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/196:00 pm -
Nonstop1h 38m
Sat 9/265:40 am -
1 stop5h 39m
Deal found 8/5![Delta logo]()
$269
This United Airlines deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/157:48 pm -
1 stop4h 11m
Sat 8/227:00 am -
1 stop4h 27m
Deal found 8/8![United Airlines logo]()
$389
This Southwest deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/196:00 am -
1 stop6h 05m
Sat 8/2212:30 pm -
2 stops8h 30m
Deal found 8/5![Southwest logo]()
$394
This Delta deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/66:00 am -
1 stop3h 44m
Sun 9/137:33 am -
Nonstop1h 42m
Deal found 8/7![Delta logo]()
$333
This Delta deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/314:50 pm -
Nonstop1h 41m
Sat 9/57:15 am -
Nonstop1h 46m
Deal found 8/8![Delta logo]()
$337
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/35:20 am -
1 stop4h 16m
Sun 9/67:15 am -
Nonstop1h 46m
Deal found 8/6![Delta logo]()
$340
This Delta deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/175:20 am -
1 stop4h 09m
Mon 9/217:33 am -
Nonstop1h 42m
Deal found 8/6![Delta logo]()
$371
This Delta deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/167:20 am -
1 stop3h 51m
Sat 8/227:15 am -
Nonstop1h 46m
Deal found 8/5![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:35 am -
Nonstop1h 43m
Fri 9/255:28 pm -
Nonstop1h 44m
Deal found 8/4![Delta logo]()
$397
This Delta deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/127:55 pm -
Nonstop1h 39m
Sun 8/167:15 am -
Nonstop1h 46m
Deal found 8/4![Delta logo]()
$399
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated August 9, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated August 9, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 8/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:23 pm -
1 stop17h 41m
Fri 9/118:20 am -
1 stop6h 31m
Deal found 8/8![Multiple Airlines logo]()
$199
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/124:35 pm -
1 stop29h 05m
Wed 9/1610:54 am -
1 stop12h 33m
Deal found 8/7![Multiple Airlines logo]()
$214
This Kiwi.com deal was found by Cheapflights users on 8/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:23 pm -
1 stop17h 41m
Fri 9/188:55 pm -
1 stop12h 52m
Deal found 8/4![Multiple Airlines logo]()
$158
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/154:23 pm -
1 stop17h 41m
Thu 9/171:19 pm -
2 stops11h 23m
Deal found 8/7![Multiple Airlines logo]()
$189
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:57 pm -
1 stop15h 44m
Mon 9/217:04 pm -
1 stop15h 39m
Deal found 8/6![Multiple Airlines logo]()
$217
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/224:23 pm -
1 stop17h 41m
Fri 9/2510:54 am -
1 stop12h 33m
Deal found 8/5![Multiple Airlines logo]()
$203
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated August 9, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/110:18 am -
1 stop23h 46m
Deal found 8/5![Multiple Airlines logo]()
$79
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/210:18 am -
1 stop23h 46m
Deal found 8/6![Multiple Airlines logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 8/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/44:23 pm -
1 stop27h 01m
Deal found 8/6![Multiple Airlines logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/94:23 pm -
1 stop17h 41m
Deal found 8/7![Multiple Airlines logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/64:23 pm -
1 stop17h 42m
Deal found 8/7![Multiple Airlines logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/810:18 am -
1 stop23h 46m
Deal found 8/7![Multiple Airlines logo]()
$99
This Trip.com deal was found by Cheapflights users on 8/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/2112:56 pm -
1 stop7h 43m
Deal found 8/7![Multiple Airlines logo]()
$102
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated August 9, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $158 (Kiwi.com) |
One-way from | $79 (Kiwi.com) |
Popular in | January |
Cheapest in | April |
Average price | $399 |
Good round-trip deal | $328 or less |
Good one-way deal | $248 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Sat 9/19
6:00 pm-7:38 pm
Nonstop1h 38m
Knoxville McGhee Tyson
Sat 9/26
5:40 am-11:19 am
1 stop5h 39m
$269
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Sun 9/6
6:00 am-9:44 am
1 stop3h 44m
Knoxville McGhee Tyson
Sun 9/13
7:33 am-9:15 am
Nonstop1h 42m
$333
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Mon 8/31
4:50 pm-6:31 pm
Nonstop1h 41m
Knoxville McGhee Tyson
Sat 9/5
7:15 am-9:01 am
Nonstop1h 46m
$337
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Thu 9/3
5:20 am-9:36 am
1 stop4h 16m
Knoxville McGhee Tyson
Sun 9/6
7:15 am-9:01 am
Nonstop1h 46m
$340
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Thu 9/17
5:20 am-9:29 am
1 stop4h 09m
Knoxville McGhee Tyson
Mon 9/21
7:33 am-9:15 am
Nonstop1h 42m
$371
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Sun 8/16
7:20 am-11:11 am
1 stop3h 51m
Knoxville McGhee Tyson
Sat 8/22
7:15 am-9:01 am
Nonstop1h 46m
$379
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Sat 8/15
7:48 pm-11:59 pm
1 stop4h 11m
Knoxville McGhee Tyson
Sat 8/22
7:00 am-11:27 am
1 stop4h 27m
$389
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 8/19
6:00 am-12:05 pm
1 stop6h 05m
Knoxville McGhee Tyson
Sat 8/22
12:30 pm-9:00 pm
2 stops8h 30m
$394
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Tue 9/22
8:35 am-10:18 am
Nonstop1h 43m
Knoxville McGhee Tyson
Fri 9/25
5:28 pm-7:12 pm
Nonstop1h 44m
$397
Quickest round-trip
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 8/12
7:55 pm-9:34 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Sun 8/16
7:15 am-9:01 am
Nonstop1h 46m
$399
Showing 1-10 of 21 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in August.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 23 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $379). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated August 9, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated August 9, 2026.
Peruse reviews from past customers who have flown with Delta from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Food
7.2
Comfort
7.8
Boarding
8.1
Entertainment
7.8
Overall
7.8
Crew
8.5
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Detroit to Knoxville
Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 9, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$425 | FlexibilityNo cancel fee | On-timeN/A |