$118+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/24. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Oct 22 — Oct 291
Round-trip
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in August or April, booked 24 days in advance, depart on a Tuesday or Thursday and return on a Thursday
Cheap flight deals from Detroit to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Detroit to KnoxvilleExplore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 22, 2026.
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:10 am -
1 stop6h 10m
Sat 10/318:25 am -
1 stop3h 40m
Deal found 9/17![Southwest logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 9/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/104:29 pm -
1 stop17h 36m
Tue 11/176:08 pm -
1 stop29h 29m
Deal found 9/20![Multiple Airlines logo]()
$262
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:10 am -
1 stop6h 10m
Thu 10/297:15 am -
1 stop6h 00m
Deal found 9/17![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:29 pm -
1 stop17h 36m
Thu 10/296:24 pm -
2 stops17h 43m
Deal found 9/17![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:03 pm -
2 stops20h 26m
Wed 10/284:14 pm -
1 stop7h 23m
Deal found 9/19![Multiple Airlines logo]()
$275
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
2 stops41h 39m
Tue 10/276:04 pm -
1 stop29h 33m
Deal found 9/21![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
2 stops41h 39m
Tue 11/36:04 pm -
1 stop29h 33m
Deal found 9/21![Multiple Airlines logo]()
$285
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:50 pm -
1 stop4h 55m
Thu 11/195:15 pm -
1 stop4h 10m
Deal found 9/17![Southwest logo]()
$286
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/124:50 pm -
1 stop4h 55m
Sat 11/142:50 pm -
1 stop3h 50m
Deal found 9/21![Southwest logo]()
$303
Best flights from Detroit to KnoxvilleDiscover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
Discover carefully curated flight deals from Detroit to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 22, 2026.
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/144:00 pm -
1 stop4h 10m
Tue 11/37:05 am -
1 stop6h 15m
Deal found 9/17![Southwest logo]()
$320
This Delta deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/148:40 am -
Nonstop1h 40m
Tue 11/37:26 am -
Nonstop1h 44m
Deal found 9/17![Delta logo]()
$367
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/316:15 am -
1 stop3h 35m
Sun 11/17:25 pm -
1 stop3h 25m
Deal found 9/17![Southwest logo]()
$340
This Delta deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/66:10 pm -
Nonstop1h 39m
Sun 11/85:40 am -
1 stop3h 47m
Deal found 9/19![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/25:50 am -
2 stops11h 00m
Thu 11/57:25 pm -
1 stop3h 30m
Deal found 9/18![Southwest logo]()
$350
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/206:25 am -
1 stop4h 29m
Tue 10/275:18 pm -
Nonstop1h 43m
Deal found 9/21![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/101:25 pm -
1 stop6h 20m
Mon 12/147:55 am -
2 stops13h 25m
Deal found 9/18![Southwest logo]()
$370
This Delta deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/308:40 am -
Nonstop1h 40m
Sun 11/15:40 am -
1 stop5h 50m
Deal found 9/21![Delta logo]()
$377
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/305:35 pm -
1 stop4h 00m
Sun 11/17:25 pm -
1 stop3h 25m
Deal found 9/17![Southwest logo]()
$373
This Southwest deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/172:10 pm -
1 stop3h 45m
Sat 10/242:55 pm -
1 stop5h 40m
Deal found 9/19![Southwest logo]()
$378
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2011:05 am -
2 stops10h 00m
Tue 10/278:20 am -
2 stops7h 10m
Deal found 9/21![Southwest logo]()
$379
Last-minute flights from Detroit to KnoxvilleDiscover last-minute flight deals from Detroit to Knoxville. Data last updated September 22, 2026 and is based on user searches.
Discover last-minute flight deals from Detroit to Knoxville. Data last updated September 22, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/186:30 am -
2 stops17h 00m
Thu 10/227:45 am -
1 stop12h 19m
Deal found 9/21![Multiple Airlines logo]()
$325
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
2 stops41h 39m
Tue 10/276:04 pm -
1 stop29h 33m
Deal found 9/21![Multiple Airlines logo]()
$283
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/205:50 pm -
2 stops41h 39m
Tue 11/36:04 pm -
1 stop29h 33m
Deal found 9/21![Multiple Airlines logo]()
$285
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:03 pm -
2 stops20h 26m
Wed 10/284:14 pm -
1 stop7h 23m
Deal found 9/19![Multiple Airlines logo]()
$275
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:10 am -
1 stop6h 10m
Sat 10/318:25 am -
1 stop3h 40m
Deal found 9/17![Southwest logo]()
$252
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:10 am -
1 stop6h 10m
Thu 10/297:15 am -
1 stop6h 00m
Deal found 9/17![Southwest logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/274:29 pm -
1 stop17h 36m
Thu 10/296:24 pm -
2 stops17h 43m
Deal found 9/17![Multiple Airlines logo]()
$271
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/284:29 pm -
1 stop15h 46m
Sun 11/16:00 am -
2 stops30h 06m
Deal found 9/17![Multiple Airlines logo]()
$328
This Southwest deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/295:35 pm -
1 stop4h 00m
Sat 10/318:25 am -
1 stop3h 40m
Deal found 9/21![Southwest logo]()
$336
One-way flights from Detroit to KnoxvilleSearch for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
Search for one-way flight options from Detroit to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 22, 2026.
This Kiwi.com deal was found by Cheapflights users on 9/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/2411:37 am -
2 stops22h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/22![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/213:03 pm -
2 stops20h 26m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$126
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/159:07 pm -
1 stop16h 24m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/148:35 pm -
1 stop16h 44m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2010:38 am -
3 stops48h 51m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Multiple Airlines logo]()
$130
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:00 am -
2 stops10h 40m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/18![Southwest logo]()
$132
This Kiwi.com deal was found by Cheapflights users on 9/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/194:29 pm -
1 stop25h 45m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/19![Multiple Airlines logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/238:25 pm -
3 stops37h 19m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 9/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/236:00 am -
1 stop17h 29m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/21![Multiple Airlines logo]()
$141
Find flight deals from Detroit to Knoxville
Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated September 22, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $252 (Southwest) |
One-way from | $118 (Kiwi.com) |
Popular in | January |
Cheapest in | August |
Average price | $428 |
Good round-trip deal | $509 or less |
Good one-way deal | $374 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Tue 3/16
5:40 pm-9:50 pm
1 stop4h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$194
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Fri 12/25
1:25 pm-7:45 pm
1 stop6h 20m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$224
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Fri 3/19
6:00 am-12:00 pm
1 stop6h 00m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$254
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 10/14
4:00 pm-8:10 pm
1 stop4h 10m
Knoxville McGhee Tyson
Tue 11/3
7:05 am-1:20 pm
1 stop6h 15m
$320
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 11/18
7:49 pm-9:29 pm
Nonstop1h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 3/17
7:55 pm-9:34 pm
Nonstop1h 39m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Fri 10/16
4:44 pm-6:24 pm
Nonstop1h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Tue 10/20
7:55 pm-9:37 pm
Nonstop1h 42m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Wed 10/14
4:44 pm-6:24 pm
Nonstop1h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
DetroitKnoxville
DTW Detroit Metropolitan Wayne County - TYS Knoxville McGhee Tyson
DTWTYS
Detroit Metropolitan Wayne County
Mon 10/19
4:44 pm-6:24 pm
Nonstop1h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-12:00 am
Nonstop0h 00m
$339
Showing 1-10 of 22 resultsSorted by cheapest first
Compare providers for flights from Detroit to Knoxville
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in September.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy1 star | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Detroit to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
DTW-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville
Prices
Airlines
How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 23 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.
What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?
Currently, August is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $341). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from DTW to TYS?
Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated September 22, 2026.
A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 13% on your trip compared to booking a flight in the evening.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 22, 2026.
Peruse reviews from past customers who have flown with Delta from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Food
7.2
Overall
7.8
Comfort
7.8
Crew
8.5
Boarding
8.1
Entertainment
7.8
Reviews
1 / 20
4.0
OkayLaura,Aug 2023
DTW - BOS
Related info for your journey
Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
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Murphy
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on September 22, 2026.
Detroit and Knoxville flights
Browse other Detroit and Knoxville flight options. Last updated on September 22, 2026.
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Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Detroit to Knoxville
Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 22, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$289 | Average$424 | FlexibilityNo cancel fee | On-timeN/A |