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$86+ Cheap flights from Detroit Metropolitan Wayne County Airport to Knoxville (DTW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/18. Fares are subject to change and may not be available on all flights or dates of travel.
DTW — TYS
Jul 25 — Aug 11
Sat 7/25
Sat 8/1
1 adult, Economy
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Find cheap flights from Detroit to Knoxville with Cheapflights

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Cheapflights Tip: The best prices from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson are usually found in April or October, booked 24 days in advance, depart on a Tuesday or Thursday and return on a Thursday

Cheap flight deals from Detroit to Knoxville

Cheapest flights from Detroit to Knoxville
Explore the most affordable flight options available from Detroit to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 25, 2026.

This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1810:18 am
DTW
-
TYS
1 stop23h 46m
Multiple Airlines
Sun 8/2312:55 pm
TYS
-
DTW
2 stops12h 09m
Multiple Airlines
Deal found 6/23$198
This Kiwi.com deal was found by Cheapflights users on 6/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/1611:00 am
DTW
-
TYS
1 stop23h 04m
Multiple Airlines
Mon 9/215:40 pm
TYS
-
DTW
1 stop19h 27m
Multiple Airlines
Deal found 6/20$206
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/319:12 am
DTW
-
TYS
1 stop23h 20m
Multiple Airlines
Mon 8/312:53 pm
TYS
-
DTW
1 stop22h 39m
Multiple Airlines
Deal found 6/21$209
This Kiwi.com deal was found by Cheapflights users on 6/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:14 am
DTW
-
TYS
1 stop22h 22m
Multiple Airlines
Mon 8/179:08 pm
TYS
-
DTW
1 stop11h 46m
Multiple Airlines
Deal found 6/24$224
This Kiwi.com deal was found by Cheapflights users on 6/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/1110:08 am
DTW
-
TYS
1 stop25h 58m
Multiple Airlines
Mon 8/176:29 pm
TYS
-
DTW
1 stop14h 25m
Multiple Airlines
Deal found 6/23$227
This Kiwi.com deal was found by Cheapflights users on 6/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/1511:00 am
DTW
-
TYS
1 stop23h 04m
Multiple Airlines
Mon 9/214:18 pm
TYS
-
DTW
1 stop19h 36m
Multiple Airlines
Deal found 6/25$231
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/22:56 pm
DTW
-
TYS
2 stops31h 04m
Multiple Airlines
Thu 8/68:29 pm
TYS
-
DTW
1 stop16h 26m
Multiple Airlines
Deal found 6/21$235
This Kiwi.com deal was found by Cheapflights users on 6/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/1310:08 am
DTW
-
TYS
1 stop22h 28m
Multiple Airlines
Thu 8/2012:55 pm
TYS
-
DTW
2 stops12h 09m
Multiple Airlines
Deal found 6/21$238

Find flight deals from Detroit to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Detroit (DTW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$198
(Kiwi.com)

One-way from

$86
(Kiwi.com)

Popular in

January

Cheapest in

April

Average price

$498

Good round-trip deal

$399 or less

Good one-way deal

$248 or less
Provider with most accurate pricing for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Detroit Metropolitan Wayne County-Knoxville McGhee Tyson flights.
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From Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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One-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 22% potential increase in price ($135 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 8% potential price decrease ($37 potential savings vs. average RT price).
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Average for round-trip flights in June 2026
Search Deals
Price to beat on a round-trip flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Price to beat on a one-way flight from Detroit Metropolitan Wayne County to Knoxville McGhee Tyson.
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Cheapflights Fare Finder

 
Customize your flight search to find flights from Detroit to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
Use the filters below to find and compare flights from Detroit Metropolitan Wayne County Airport to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Sat 8/15

6:35 am-11:55 am

2 stops5h 20m

Knoxville McGhee Tyson

Sat 8/22

6:50 am-9:00 pm

2 stops14h 10m

$281

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 8/4

6:00 am-1:05 pm

2 stops7h 05m

Knoxville McGhee Tyson

Fri 8/7

5:45 pm-10:35 pm

1 stop4h 50m

$297
Quickest round-trip

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Fri 8/14

4:00 pm-5:42 pm

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 8/16

7:15 am-9:01 am

Nonstop1h 46m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 7/30

8:40 am-10:22 am

Nonstop1h 42m

Knoxville McGhee Tyson

Sun 8/2

7:15 am-9:01 am

Nonstop1h 46m

$299

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 7/28

8:25 am-2:48 pm

1 stop6h 23m

Knoxville McGhee Tyson

Sat 8/1

11:31 am-1:15 pm

Nonstop1h 44m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 8/18

6:19 pm-11:52 pm

1 stop5h 33m

Knoxville McGhee Tyson

Sun 8/23

7:15 am-9:01 am

Nonstop1h 46m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 8/13

8:40 am-10:20 am

Nonstop1h 40m

Knoxville McGhee Tyson

Mon 8/17

5:40 am-10:10 am

1 stop4h 30m

$309

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 9/3

7:20 am-1:34 pm

1 stop6h 14m

Knoxville McGhee Tyson

Sun 9/6

6:00 am-10:09 am

1 stop4h 09m

$319

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Tue 8/11

6:25 am-2:20 pm

2 stops7h 55m

Knoxville McGhee Tyson

Mon 8/17

7:10 am-3:10 pm

2 stops8h 00m

$331

DetroitKnoxville

DTW - TYS

DTWTYS

Detroit Metropolitan Wayne County

Thu 7/30

1:25 pm-10:35 pm

2 stops9h 10m

Knoxville McGhee Tyson

Sat 8/1

1:35 pm-10:30 pm

2 stops8h 55m

$361

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/23

Showing 1-10 of 20 resultsSorted by cheapest first
1
2

Compare providers for flights from Detroit to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Detroit to Knoxville in June.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars
CheapTicketsDealPrice Accuracy1 starTrust Score*3 stars
PricelinePrice Accuracy1 starTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Detroit Metropolitan Wayne County Airport-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Detroit Metropolitan Wayne County Airport-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Detroit Metropolitan Wayne County Airport-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Detroit Metropolitan Wayne County Airport-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Detroit to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Detroit with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Detroit Metropolitan Wayne County Airport to Knoxville

How far ahead should I book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

The best time to book flights from Detroit Metropolitan Wayne County Airport to Knoxville is 23 days before your desired departure date. The cost of your flight will likely increase significantly if you book two weeks in advance of your flight.

What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $379). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from DTW to TYS?

Find hourly flight availability from Detroit to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 25, 2026.

A simple way to save on the total cost of your ticket is to fly from Detroit Metropolitan Wayne County Airport to Knoxville in the morning. If you’re flexible enough to do this you can expect to save up to 20% on your trip compared to booking a flight in the evening.

How much does it cost to fly round-trip from Detroit Metropolitan Wayne County Airport to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 25, 2026.
Peruse reviews from past customers who have flown with Delta from Detroit Metropolitan Wayne County Airport to Knoxville to help guide your decision. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.8
Good
8,438 reviews

Boarding

8.1

Food

7.2

Overall

7.8

Entertainment

7.8

Crew

8.5

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Laura,Aug 2023

DTW - BOS

Finally got on a flight to Boston and all went ok. We were the last to board and sat in the last seats on the plane. Not particularly treated well after waiting all day to travel.
Delta
7.8
Good
8,438 reviews
Delta
7.8
Good
8,438 reviews

Boarding

8.1

Food

7.2

Overall

7.8

Entertainment

7.8

Crew

8.5

Comfort

7.8

Reviews

1 / 20
4.0
Okay

Laura,Aug 2023

DTW - BOS

Finally got on a flight to Boston and all went ok. We were the last to board and sat in the last seats on the plane. Not particularly treated well after waiting all day to travel.

Related info for your journey

Find useful and relevant information for your journey from Detroit to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airports do I use to fly from Detroit to Knoxville?

    To fly from Detroit to Knoxville, you need to book a flight from Detroit Metropolitan Wayne County (DTW) to McGhee Tyson (TYS). Nonstop flights to Knoxville McGhee Tyson from Detroit Metropolitan Wayne County take 1h 38m on average. When it comes time to book airfare, you have a few options: there are 10 outbound flights from Detroit Metropolitan Wayne County to McGhee Tyson offered by 1 airline.

  • How long is the flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    There are many flights that can get you from Detroit Metropolitan Wayne County Airport to Knoxville in 1h 42m. Fly via Southwest or Delta to get the fastest option. There are 444 mi between Detroit Metropolitan Wayne County Airport and Knoxville. When browsing for deals, the options you’ll see will be for both nonstop flights and flights with stops.

  • What is the cheapest airline to fly from Detroit Metropolitan Wayne County Airport to Knoxville round-trip?

    Delta, at $299, was found to be the cheapest airline from Detroit Metropolitan Wayne County Airport to Knoxville.. You may be able to fly from Detroit Metropolitan Wayne County Airport to Knoxville for 36% less than the average price by searching for this airline.

  • What are the most reliable airlines from Detroit Metropolitan Wayne County Airport to Knoxville?

    Looking for the most reliable airlines to get you to your destination on time? Our data shows these are most likely to get you from Detroit Metropolitan Wayne County Airport to Knoxville on time: Air France (78%), Aeromexico (72%), Virgin Atlantic (71%).

  • What are the cheapest flights from Detroit Metropolitan Wayne County Airport to Knoxville?

    The cheapest flight price from Detroit Metropolitan Wayne County Airport to Knoxville is $248. On average you can expect to pay $592. The most popular route, (Detroit Metropolitan Wayne County - Knoxville McGhee Tyson), can usually be booked for $198.

  • Can I find deals for flights from Detroit to Knoxville that include hotel bookings?

    Yes. In addition to deals on Detroit to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Detroit to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Detroit to Knoxville.

  • Can I find deals for business class flights from Detroit to Knoxville?

    Yes. Cheapflights offers flight deals from Detroit to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Detroit Metropolitan Wayne County Airport to Knoxville?

    Currently, April is the cheapest month in which you can book a flight from Detroit Metropolitan Wayne County Airport to Knoxville (average of $379). Flying from Detroit Metropolitan Wayne County Airport to Knoxville in January is currently the most expensive (average of $877). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Morristown
Bryson City
Murphy
Alcoa

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Alternative routes for Detroit to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
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Top airline flying from Detroit to Knoxville

Discover the top airline that operate flights from Detroit to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 25, 2026.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$299Average$420FlexibilityNo cancel feeOn-timeN/A

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