$105+ Cheap flights from Knoxville to Detroit Metropolitan Wayne County Airport (TYS - DTW)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/29. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — DTW
May 29 — Jun 51
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Detroit with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Detroit
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to DetroitExplore the most affordable flight options available from Knoxville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
Explore the most affordable flight options available from Knoxville to Detroit. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 29, 2026.
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:19 pm
TYS
- DTW
1 stop16h 16m
Frontier
Fri 6/57:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 4/28![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/512:49 pm
TYS
- DTW
2 stops24h 53m
Multiple Airlines
Mon 6/810:08 am
DTW
- TYS
1 stop13h 31m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$226
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:32 pm
TYS
- DTW
1 stop16h 03m
Frontier
Mon 6/87:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 4/29![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:19 pm
TYS
- DTW
1 stop11h 44m
Multiple Airlines
Thu 6/46:50 am
DTW
- TYS
2 stops33h 50m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:00 am
TYS
- DTW
2 stops16h 39m
Multiple Airlines
Wed 6/39:25 am
DTW
- TYS
1 stop8h 56m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$248
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/31:02 pm
TYS
- DTW
2 stops11h 37m
Multiple Airlines
Fri 6/59:58 pm
DTW
- TYS
1 stop13h 51m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$255
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1012:40 pm
TYS
- DTW
2 stops12h 00m
Multiple Airlines
Sat 7/188:29 pm
DTW
- TYS
1 stop15h 40m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$263
Best flights from Knoxville to DetroitDiscover carefully curated flight deals from Knoxville to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
Discover carefully curated flight deals from Knoxville to Detroit that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 29, 2026.
This CheapOair deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/58:32 pm
TYS
- DTW
1 stop16h 03m
Frontier
Mon 6/87:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 4/29![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/93:38 pm
TYS
- DTW
1 stop6h 27m
Multiple Airlines
Mon 7/136:10 am
DTW
- TYS
2 stops15h 50m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$278
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/1011:41 am
TYS
- DTW
Nonstop1h 44m
Delta
Sat 7/187:59 pm
DTW
- TYS
Nonstop1h 39m
Delta
Deal found 4/26![Delta logo]()
$339
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/167:45 am
TYS
- DTW
1 stop8h 25m
Southwest
Tue 5/194:10 pm
DTW
- TYS
1 stop3h 30m
Southwest
Deal found 4/25![Southwest logo]()
$354
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/311:27 am
TYS
- DTW
Nonstop1h 49m
Delta
Mon 7/612:35 pm
DTW
- TYS
Nonstop1h 34m
Delta
Deal found 4/29![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/57:51 am
TYS
- DTW
Nonstop1h 39m
Delta
Mon 6/81:39 pm
DTW
- TYS
Nonstop1h 40m
Delta
Deal found 4/29![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/77:15 am
TYS
- DTW
Nonstop1h 49m
Delta
Sun 6/147:59 pm
DTW
- TYS
Nonstop1h 42m
Delta
Deal found 4/25![Delta logo]()
$339
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/237:15 am
TYS
- DTW
Nonstop1h 46m
Delta
Mon 7/277:20 am
DTW
- TYS
1 stop3h 45m
Delta
Deal found 4/26![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/197:46 pm
TYS
- DTW
1 stop4h 12m
Delta
Sat 6/208:25 am
DTW
- TYS
Nonstop1h 46m
Delta
Deal found 4/26![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:59 pm
TYS
- DTW
1 stop6h 59m
Delta
Fri 6/57:50 pm
DTW
- TYS
Nonstop1h 35m
Delta
Deal found 4/28![Delta logo]()
$349
Last-minute flights from Knoxville to DetroitDiscover last-minute flight deals from Knoxville to Detroit. Data last updated April 29, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Detroit. Data last updated April 29, 2026 and is based on user searches.
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 5/118:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Fri 5/157:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 4/26![Frontier logo]()
$301
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/134:25 pm
TYS
- DTW
1 stop16h 38m
Multiple Airlines
Sun 5/176:30 am
DTW
- TYS
2 stops35h 00m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$314
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/157:30 am
TYS
- DTW
1 stop16h 23m
Multiple Airlines
Tue 5/191:31 pm
DTW
- TYS
2 stops28h 28m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$325
This Southwest deal was found by Cheapflights users on 4/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/205:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Wed 5/274:10 pm
DTW
- TYS
1 stop3h 30m
Southwest
Deal found 4/25![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/278:00 am
TYS
- DTW
2 stops16h 39m
Multiple Airlines
Wed 6/39:25 am
DTW
- TYS
1 stop8h 56m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$248
This Southwest deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/275:50 pm
TYS
- DTW
1 stop3h 45m
Southwest
Wed 6/31:20 pm
DTW
- TYS
1 stop7h 30m
Southwest
Deal found 4/29![Southwest logo]()
$284
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:19 pm
TYS
- DTW
1 stop11h 44m
Multiple Airlines
Thu 6/46:50 am
DTW
- TYS
2 stops33h 50m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$242
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/298:19 pm
TYS
- DTW
1 stop16h 16m
Frontier
Fri 6/57:55 am
DTW
- TYS
1 stop11h 38m
Frontier
Deal found 4/28![Frontier logo]()
$191
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:55 pm
TYS
- DTW
2 stops18h 57m
Multiple Airlines
Fri 6/512:44 pm
DTW
- TYS
1 stop23h 05m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$271
One-way flights from Knoxville to DetroitSearch for one-way flight options from Knoxville to Detroit. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
Search for one-way flight options from Knoxville to Detroit. Find affordable one-way fares based on user searches. Data last updated April 29, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2912:55 pm
TYS
- DTW
2 stops24h 47m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$105
This CheapOair deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/248:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 4/26![Frontier logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/2412:40 pm
TYS
- DTW
2 stops12h 00m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$116
This Kiwi.com deal was found by Cheapflights users on 4/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/254:05 pm
TYS
- DTW
1 stop6h 00m
Multiple Airlines
Deal found 4/27![Multiple Airlines logo]()
$120
This CheapOair deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/88:32 pm
TYS
- DTW
1 stop27h 27m
Frontier
Deal found 4/28![Frontier logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/241:02 pm
TYS
- DTW
1 stop10h 53m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$127
This Kiwi.com deal was found by Cheapflights users on 4/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/289:19 pm
TYS
- DTW
2 stops27h 20m
Multiple Airlines
Deal found 4/29![Multiple Airlines logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 4/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/221:05 pm
TYS
- DTW
1 stop10h 45m
Multiple Airlines
Deal found 4/28![Multiple Airlines logo]()
$131
This Kiwi.com deal was found by Cheapflights users on 4/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/211:03 pm
TYS
- DTW
1 stop28h 13m
Multiple Airlines
Deal found 4/26![Multiple Airlines logo]()
$135
Find flight deals from Knoxville to Detroit
Discover tips and strategies to find the most affordable flight options for your journey from Knoxville (TYS) to Detroit (DTW). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated April 29, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $191 (CheapOair) |
One-way from | $105 (Kiwi.com) |
Popular in | March |
Cheapest in | January |
Average price | $449 |
Good round-trip deal | $394 or less |
Good one-way deal | $237 or less |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Detroit that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
Use the filters below to find and compare flights from Knoxville to Detroit Metropolitan Wayne County Airport that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 6/5
8:32 pm-12:35 pm
1 stop16h 03m
Detroit Metropolitan Wayne County
Mon 6/8
7:55 am-7:33 pm
1 stop11h 38m
$236
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Thu 7/9
3:38 pm-10:05 pm
1 stop6h 27m
Detroit Metropolitan Wayne County
Mon 7/13
6:10 am-10:00 pm
2 stops15h 50m
$278
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 7/10
11:41 am-1:25 pm
Nonstop1h 44m
Detroit Metropolitan Wayne County
Sat 7/18
7:59 pm-9:38 pm
Nonstop1h 39m
$339
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 7/3
11:27 am-1:16 pm
Nonstop1h 49m
Detroit Metropolitan Wayne County
Mon 7/6
12:35 pm-2:09 pm
Nonstop1h 34m
$339
Quickest round-trip
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 6/5
7:51 am-9:30 am
Nonstop1h 39m
Detroit Metropolitan Wayne County
Mon 6/8
1:39 pm-3:19 pm
Nonstop1h 40m
$339
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Sun 6/7
7:15 am-9:04 am
Nonstop1h 49m
Detroit Metropolitan Wayne County
Sun 6/14
7:59 pm-9:41 pm
Nonstop1h 42m
$339
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Thu 7/23
7:15 am-9:01 am
Nonstop1h 46m
Detroit Metropolitan Wayne County
Mon 7/27
7:20 am-11:05 am
1 stop3h 45m
$349
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 6/19
7:46 pm-11:58 pm
1 stop4h 12m
Detroit Metropolitan Wayne County
Sat 6/20
8:25 am-10:11 am
Nonstop1h 46m
$349
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Fri 5/29
5:59 pm-12:58 am
1 stop6h 59m
Detroit Metropolitan Wayne County
Fri 6/5
7:50 pm-9:25 pm
Nonstop1h 35m
$349
KnoxvilleDetroit
TYS - DTW
TYSDTW
Knoxville McGhee Tyson
Sat 5/16
7:45 am-4:10 pm
1 stop8h 25m
Detroit Metropolitan Wayne County
Tue 5/19
4:10 pm-7:40 pm
1 stop3h 30m
$354
Showing 1-10 of 19 resultsSorted by cheapest first
Compare providers for flights from Knoxville to Detroit
Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Knoxville to Detroit in April.
| Provider | Price Accuracy | Trust Score* |
|---|---|---|
| Price Accuracy1 star | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars | |
| Price Accuracy3 stars | Trust Score*3 stars |
- Most accurate provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Knoxville-Detroit Metropolitan Wayne County Airport flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Knoxville-Detroit Metropolitan Wayne County Airport flight searches over the past month and is updated monthly.
- Most trusted provider: When it comes to deals on Knoxville-Detroit Metropolitan Wayne County Airport flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Knoxville-Detroit Metropolitan Wayne County Airport flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.
Best time to book a flight from Knoxville to Detroit
Have a flexible travel schedule? Discover the best time to fly to Detroit from Knoxville with our price prediction graph.
TYS-DTW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Detroit Metropolitan Wayne County Airport
Prices
Airlines
What is the cheapest month to book a flight from Knoxville to Detroit Metropolitan Wayne County Airport?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Detroit Metropolitan Wayne County Airport (average of $324). Flying from Knoxville to Detroit Metropolitan Wayne County Airport in March is currently the most expensive (average of $659). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to DTW?
Find hourly flight availability from Knoxville to Detroit. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 29, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Detroit Metropolitan Wayne County Airport as you normally would.
Reviews of airlines servicing Detroit
Get insights into the airlines that provide service to Detroit. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Detroit. Reviews last updated April 29, 2026.
Read reviews from past customers who have flown Delta from Knoxville to Detroit Metropolitan Wayne County Airport. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Food
7.2
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Food
7.2
Crew
8.5
Overall
7.9
Boarding
8.1
Comfort
7.9
Entertainment
7.8
Reviews
1 / 20
6.0
GoodJim,Nov 2025
AVL - ATL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Detroit. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Detroit Metropolitan Wayne County Airport?
Book flights to Detroit Metropolitan Wayne County Airport if you plan to visit one of these locationsDearborn
Troy
Southfield
Sterling Heights
Warren
Auburn Hills
Pontiac
Southgate
Allen Park
Romulus
Rochester Hills
Roseville
Utica
Monroe
Wixom
Ypsilanti
Livonia
Plymouth
Fremont
Port Huron
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Detroit flight routes
Flights by cabin class
Other flight options
Other flights from Knoxville
Popular flights
Alternative routes for Knoxville to Detroit
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Detroit by adding a car rental and/or hotel reservation to your travel itinerary.
Other flights to Detroit
Explore flights to Detroit departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Search flights from Knoxville to Detroit by cabin class
Find flights from Knoxville to Detroit, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Detroit flights
Browse other Knoxville and Detroit flight options. Last updated on April 29, 2026.
Other flights from Knoxville
Browse through other flights departing from Knoxville. Flights are based on user searches made on Cheapflights and were last updated on April 29, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top airline flying from Knoxville to Detroit
Discover the top airline that operate flights from Knoxville to Detroit. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 29, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$299 | Average$450 | FlexibilityNo cancel fee | On-timeN/A |