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Knoxville

Cheap flights from Irvine, CA to Knoxville (TYS)

LAX — TYS
Dec 4 — Dec 111
Fri 12/4
Fri 12/11
1 adult, Economy
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Find flight deals from Irvine to Knoxville

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Popular in

June

Cheapest in

February

Average price

$493
Provider with most accurate pricing for Los Angeles-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Los Angeles-Knoxville McGhee Tyson flights.
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Highest demand for flights based on searches. 5% potential increase in price ($30 potential increase over avg. RT price).
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Cheapest flight prices on average. 1% potential price decrease ($7 potential savings vs. average RT price).
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Average for round-trip flights in November 2026
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Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Irvine to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
Southwest
8.0
Very good
4,212 reviews
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
Delta
7.8
Good
8,697 reviews
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
United Airlines
7.3
Good
10,461 reviews
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
American Airlines
7.0
Good
12,231 reviews
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.
Frontier
5.5
Fair
2,511 reviews
Southwest
8.0
Very good
4,212 reviews

Food

7.0

Boarding

8.1

Crew

8.6

Comfort

8.0

Entertainment

7.5

Overall

8.0

Reviews

1 / 20
8.0
Excellent

La Tracimeldamarcos,Jun 2026

LAX - SLC

The second flight was not as comfortable as the first as we had to change planes to what seemed to be a slightly older aircraft. The seats weren’t as comfortable as the other plane. But it wasn’t bad.

Related info for your journey

  • What airport do you fly into for flights to Knoxville from Irvine?

    For a flight from Irvine to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 inbound flights from Irvine per day. 6 airlines have flights to Knoxville McGhee Tyson from Irvine on a regular basis.

  • What are the cheapest airlines to fly from Irvine to Knoxville one-way?

    One-way options have recently been found by users for as low as $91 on Frontier. Other airlines that offer cheap prices include Delta from $149 and American Airlines from $172 one-way.

  • Can I find deals for flights from Irvine to Knoxville that include hotel bookings?

    Yes. In addition to deals on Irvine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Irvine to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Knoxville.

  • Can I find deals for business class flights from Irvine to Knoxville?

    Yes. Cheapflights offers flight deals from Irvine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Morristown
Newport
Bryson City
Crossville
Murphy

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Top 6 airlines flying from Irvine to Knoxville

AirlineCheapestAverageFlexibilityOn-time
FrontierCheapest$142Average$296FlexibilityNo cancel feeOn-time62%
DeltaCheapest$229Average$431FlexibilityNo cancel feeOn-timeN/A
SouthwestCheapest$278Average$531FlexibilityNo cancel feeOn-time63%
JetBlueCheapest$279Average$516FlexibilityNo cancel feeOn-time62%
American AirlinesCheapest$308Average$530FlexibilityNo cancel feeOn-time71%
United AirlinesCheapest$319Average$506FlexibilityNo cancel feeOn-time69%

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