$131+ Cheap flights from Irvine, CA to Knoxville (TYS)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/17. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — TYS
Oct 19 — Oct 261
Round-trip
1 adult, Economy
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Find cheap flights from Irvine to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Irvine to Knoxville
Cheapest
Best
Last-minute
One-way
Cheapest flights from Irvine to KnoxvilleExplore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on September 19, 2026.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:35 pm -
1 stop7h 10m
Tue 10/205:45 am -
1 stop8h 11m
Deal found 9/16![United Airlines logo]()
$261
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:15 am -
1 stop7h 25m
Sat 11/75:20 pm -
1 stop8h 05m
Deal found 9/15![Southwest logo]()
$262
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/36:40 am -
2 stops10h 05m
Tue 11/105:15 pm -
1 stop9h 20m
Deal found 9/15![Southwest logo]()
$266
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:57 pm -
1 stop20h 52m
Mon 11/29:42 pm -
1 stop14h 37m
Deal found 9/18![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:42 am -
1 stop23h 29m
Thu 11/56:30 am -
1 stop11h 16m
Deal found 9/15![Multiple Airlines logo]()
$272
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop6h 26m
Tue 11/311:45 am -
1 stop9h 04m
Deal found 9/15![Delta logo]()
$277
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:50 am -
1 stop6h 15m
Mon 11/27:25 pm -
1 stop9h 00m
Deal found 9/16![Southwest logo]()
$279
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/710:05 pm -
1 stop9h 15m
Wed 11/115:40 am -
1 stop7h 25m
Deal found 9/14![Delta logo]()
$286
Best flights from Irvine to KnoxvilleDiscover carefully curated flight deals from Irvine to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
Discover carefully curated flight deals from Irvine to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated September 19, 2026.
This Delta deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2911:16 am -
1 stop8h 46m
Wed 11/411:45 am -
1 stop9h 04m
Deal found 9/18![Delta logo]()
$363
This Southwest deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/46:40 am -
2 stops10h 10m
Wed 11/114:15 pm -
1 stop8h 50m
Deal found 9/18![Southwest logo]()
$368
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/2711:17 pm -
1 stop9h 13m
Thu 10/2910:43 am -
1 stop7h 46m
Deal found 9/17![United Airlines logo]()
$414
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/21:05 am -
2 stops8h 15m
Fri 11/65:25 pm -
2 stops9h 45m
Deal found 9/16![Southwest logo]()
$375
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 12/118:30 am -
2 stops7h 15m
Mon 12/141:00 pm -
1 stop9h 05m
Deal found 9/15![Southwest logo]()
$387
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 11/1610:59 pm -
1 stop7h 56m
Wed 11/2511:43 am -
1 stop10h 07m
Deal found 9/14![Delta logo]()
$435
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/288:20 am -
2 stops9h 45m
Sun 11/15:25 pm -
2 stops9h 00m
Deal found 9/15![Southwest logo]()
$395
This United Airlines deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/37:00 am -
1 stop7h 08m
Sat 10/175:45 am -
1 stop8h 11m
Deal found 9/18![United Airlines logo]()
$485
This Delta deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/156:00 am -
1 stop8h 49m
Thu 11/265:40 am -
1 stop7h 25m
Deal found 9/14![Delta logo]()
$467
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/219:25 am -
2 stops8h 40m
Mon 10/267:25 pm -
2 stops7h 50m
Deal found 9/17![Southwest logo]()
$425
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/2210:20 pm -
1 stop11h 50m
Sat 10/242:55 pm -
1 stop10h 50m
Deal found 9/17![Southwest logo]()
$476
Last-minute flights from Irvine to KnoxvilleDiscover last-minute flight deals from Irvine to Knoxville. Data last updated September 19, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to Knoxville. Data last updated September 19, 2026 and is based on user searches.
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1311:35 pm -
1 stop7h 10m
Tue 10/205:45 am -
1 stop8h 11m
Deal found 9/16![United Airlines logo]()
$261
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:05 pm -
1 stop9h 15m
Tue 10/205:18 pm -
1 stop8h 16m
Deal found 9/15![Delta logo]()
$286
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop6h 26m
Tue 11/311:45 am -
1 stop9h 04m
Deal found 9/15![Delta logo]()
$277
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/271:05 pm -
1 stop6h 57m
Thu 11/57:26 am -
1 stop10h 07m
Deal found 9/15![Delta logo]()
$287
This Southwest deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/2811:50 am -
1 stop6h 15m
Mon 11/27:25 pm -
1 stop9h 00m
Deal found 9/16![Southwest logo]()
$279
This Kiwi.com deal was found by Cheapflights users on 9/18. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/299:57 pm -
1 stop20h 52m
Mon 11/29:42 pm -
1 stop14h 37m
Deal found 9/18![Multiple Airlines logo]()
$270
This Southwest deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/319:15 am -
1 stop7h 25m
Sat 11/75:20 pm -
1 stop8h 05m
Deal found 9/15![Southwest logo]()
$262
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:42 am -
1 stop23h 29m
Thu 11/56:30 am -
1 stop11h 16m
Deal found 9/15![Multiple Airlines logo]()
$272
This Kiwi.com deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/3111:42 am -
1 stop23h 29m
Mon 11/29:42 pm -
1 stop14h 37m
Deal found 9/15![Multiple Airlines logo]()
$288
One-way flights from Irvine to KnoxvilleSearch for one-way flight options from Irvine to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
Search for one-way flight options from Irvine to Knoxville. Find affordable one-way fares based on user searches. Data last updated September 19, 2026.
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 11/176:40 am -
1 stop5h 50m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$131
This Delta deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/1310:05 pm -
1 stop9h 15m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![Delta logo]()
$139
This United Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/610:30 pm -
1 stop9h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![United Airlines logo]()
$146
This American Airlines deal was found by Cheapflights users on 9/15. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:35 am -
1 stop7h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/15![American Airlines logo]()
$148
This United Airlines deal was found by Cheapflights users on 9/16. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/1910:30 pm -
1 stop9h 07m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/16![United Airlines logo]()
$149
This Southwest deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/81:05 am -
2 stops8h 05m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Southwest logo]()
$154
This Kiwi.com deal was found by Cheapflights users on 9/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/1812:21 am -
1 stop12h 30m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/14![Multiple Airlines logo]()
$159
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/291:24 pm -
2 stops24h 27m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$162
This American Airlines deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 11/276:00 am -
1 stop7h 36m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![American Airlines logo]()
$176
This Kiwi.com deal was found by Cheapflights users on 9/17. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/57:36 pm -
1 stop23h 59m
Wed 12/3112:00 am -
Nonstop0h 00m
Deal found 9/17![Multiple Airlines logo]()
$178
Find flight deals from Irvine to Knoxville
Keep the following information in mind while searching for Irvine to Knoxville flight deals. Data was last updated September 19, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $261 (United Airlines) |
One-way from | $131 (Southwest) |
Popular in | June |
Cheapest in | February |
Average price | $454 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
Use the filters below to find and compare flights from Irvine to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Tue 11/17
6:40 am-3:30 pm
1 stop5h 50m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$131
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Tue 10/13
10:05 pm-10:20 am
1 stop9h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$139
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Tue 10/6
10:30 pm-10:37 am
1 stop9h 07m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$146
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Mon 10/19
10:30 pm-10:37 am
1 stop9h 07m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$149
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Wed 10/14
10:35 pm-9:45 am
1 stop8h 10m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$189
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Tue 10/20
7:00 am-11:59 pm
2 stops13h 59m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$193
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Sun 10/18
10:05 pm-10:20 am
1 stop9h 15m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$234
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Fri 10/16
11:05 pm-9:45 am
1 stop7h 40m
Knoxville McGhee Tyson
Wed 12/31
12:00 am-9:00 pm
Nonstop0h 00m
$237
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Thu 10/29
11:16 am-11:02 pm
1 stop8h 46m
Knoxville McGhee Tyson
Wed 11/4
11:45 am-5:49 pm
1 stop9h 04m
$363
Los AngelesKnoxville
LAX Los Angeles - TYS Knoxville McGhee Tyson
LAXTYS
Los Angeles
Wed 11/4
6:40 am-7:50 pm
2 stops10h 10m
Knoxville McGhee Tyson
Wed 11/11
4:15 pm-10:05 pm
1 stop8h 50m
$368
Showing 1-10 of 19 resultsSorted by cheapest first
Best time to book a flight from Irvine to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.
LAX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Knoxville
IR9-TYS
LAX-TYS
How much does it cost to fly round-trip from Irvine to Knoxville?
Airfare is below average for this route at the moment.
Irvine to Knoxville flights typically cost between $391 and $554 in October.The cheapest round-trip price found within the last 5 days was $261 on United Airlines (Oct 13-Oct 20).
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated September 19, 2026.
Read reviews from past customers who have flown Southwest,Delta, andUnited Airlines from Irvine to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Crew
8.6
Entertainment
7.5
Food
7.0
Boarding
8.1
Overall
8.0
Comfort
8.0
Reviews
1 / 20
8.0
ExcellentLa Tracimeldamarcos,Jun 2026
LAX - SLC
Related info for your journey
Find useful and relevant information for your journey from Irvine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Morristown
Bryson City
Murphy
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Popular flight searches
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Top 6 airlines flying from Irvine to Knoxville
Discover the top 6 airlines that operate flights from Irvine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 7,457,451 searches. Data last updated September 19, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$142 | Average$296 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$229 | Average$460 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$279 | Average$516 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$288 | Average$518 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$318 | Average$504 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$324 | Average$521 | FlexibilityNo cancel fee | On-time63% |