How long is the flight from Irvine to Knoxville?

Delta can get you from Irvine to Knoxville in just under 7h 41m. Your travel time can differ by up to . Airlines will cover a distance of 1944 mi.

What are the cheapest airlines to fly from Irvine to Knoxville one-way?

One-way options have recently been found by users for as low as $85 on Frontier. Other airlines that offer cheap prices include Delta from $178 and United Airlines from $194 one-way.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

What are the most popular airlines that fly from Irvine to Knoxville?

Before booking your flight from Irvine to Knoxville check out the most popular airlines for this route: American Airlines, Delta or United Airlines.

What airport do you fly into for flights to Knoxville from Irvine?

For a flight from Irvine to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 inbound flights from Irvine per day. 4 airlines have flights to Knoxville McGhee Tyson from Irvine on a regular basis.

Can I find deals for flights from Irvine to Knoxville that include hotel bookings?

Yes. In addition to deals on Irvine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Irvine to Knoxville?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Knoxville.

Can I find deals for business class flights from Irvine to Knoxville?

Yes. Cheapflights offers flight deals from Irvine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$109+ Flights from Irvine to Knoxville

Q: How much does it cost to fly round-trip from Irvine to Knoxville?

Airfare is below average for this route at the moment. Irvine to Knoxville flights typically cost between $392 and $742 in February. The cheapest round-trip price found within the last 3 days was $217 on Frontier (Feb 20-Feb 23).

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Cheapflights Tip: The best prices from Irvine to Knoxville McGhee Tyson are usually found in August or July, booked 73 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Irvine to Knoxville

Cheapest flights from Irvine to Knoxville
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Fri 1/97:35 amTYS - LAX

1 stop14h 46mMultiple Airlines

Deal found 12/24

$302

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Mon 1/54:46 pmTYS - LAX

1 stop22h 56mMultiple Airlines

Deal found 12/24

$320

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Sun 1/44:26 pmTYS - LAX

2 stops23h 56mMultiple Airlines

Deal found 12/24

$345

Wed 12/311:30 pmLAX - TYS

1 stop6h 43mDelta

Wed 1/76:10 pmTYS - LAX

1 stop7h 47mDelta

Deal found 12/24

$358

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Thu 1/89:29 amTYS - LAX

1 stop16h 27mMultiple Airlines

Deal found 12/24

$362

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Tue 1/67:22 pmTYS - LAX

2 stops21h 11mMultiple Airlines

Deal found 12/24

$384

Tue 12/306:34 amLAX - TYS

1 stop6h 17mFrontier

Thu 1/84:23 pmTYS - LAX

1 stop10h 45mFrontier

Deal found 12/24

$403

Tue 12/3012:15 pmLAX - TYS

1 stop6h 00mDelta

Tue 1/61:00 pmTYS - LAX

1 stop11h 02mDelta

Deal found 12/24

$417

Best flights from Irvine to Knoxville
Discover carefully curated flight deals from Irvine to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated December 25, 2025.

Tue 2/37:07 pmLAX - TYS

2 stops17h 50mMultiple Airlines

Fri 2/67:35 amTYS - LAX

1 stop10h 37mMultiple Airlines

Deal found 12/22

$261

Tue 2/37:30 amLAX - TYS

1 stop7h 41mDelta

Tue 2/101:00 pmTYS - LAX

1 stop8h 51mDelta

Deal found 12/24

$277

Tue 2/35:00 amLAX - TYS

1 stop7h 14mUnited Airlines

Fri 2/69:05 amTYS - LAX

1 stop8h 30mUnited Airlines

Deal found 12/23

$357

Thu 2/196:00 amLAX - TYS

1 stop8h 11mAmerican Airlines

Sun 2/224:30 pmTYS - LAX

1 stop8h 27mAmerican Airlines

Deal found 12/24

$384

Fri 2/2011:11 amLAX - TYS

1 stop8h 50mMultiple Airlines

Sun 2/228:30 amTYS - LAX

1 stop12h 24mMultiple Airlines

Deal found 12/23

$267

Wed 1/73:42 pmLAX - TYS

1 stop23h 57mMultiple Airlines

Sat 1/1011:59 amTYS - LAX

1 stop13h 57mMultiple Airlines

Deal found 12/24

$273

Wed 1/288:00 amLAX - TYS

1 stop9h 47mDelta

Thu 1/291:00 pmTYS - LAX

1 stop11h 00mDelta

Deal found 12/23

$304

Wed 2/114:40 pmLAX - TYS

1 stop22h 12mMultiple Airlines

Mon 2/169:36 pmTYS - LAX

2 stops36h 39mMultiple Airlines

Deal found 12/23

$279

Wed 2/181:05 amLAX - TYS

2 stops18h 05mMultiple Airlines

Mon 2/231:40 pmTYS - LAX

1 stop21h 35mMultiple Airlines

Deal found 12/24

$283

Wed 12/311:30 pmLAX - TYS

1 stop6h 43mDelta

Wed 1/76:10 pmTYS - LAX

1 stop7h 47mDelta

Deal found 12/24

$358

Last-minute flights from Irvine to Knoxville
Discover last-minute flight deals from Irvine to Knoxville. Data last updated December 25, 2025 and is based on user searches.

Wed 12/316:34 amLAX - TYS

1 stop11h 05mMultiple Airlines

Fri 1/97:35 amTYS - LAX

1 stop14h 46mMultiple Airlines

Deal found 12/24

$302

Wed 1/73:42 pmLAX - TYS

1 stop23h 57mMultiple Airlines

Sat 1/1011:59 amTYS - LAX

1 stop13h 57mMultiple Airlines

Deal found 12/24

$273

Sun 1/119:46 pmLAX - TYS

1 stop16h 04mMultiple Airlines

Wed 1/144:47 pmTYS - LAX

1 stop33h 09mMultiple Airlines

Deal found 12/22

$293

Thu 1/159:46 pmLAX - TYS

1 stop16h 04mMultiple Airlines

Sun 1/1810:00 amTYS - LAX

1 stop24h 59mMultiple Airlines

Deal found 12/24

$306

Sat 1/1711:45 pmLAX - TYS

1 stop8h 46mAmerican Airlines

Wed 1/216:00 amTYS - LAX

1 stop8h 12mAmerican Airlines

Deal found 12/24

$288

Wed 1/288:00 amLAX - TYS

1 stop9h 47mDelta

Thu 1/291:00 pmTYS - LAX

1 stop11h 00mDelta

Deal found 12/23

$304

Thu 1/296:26 pmLAX - TYS

1 stop19h 24mMultiple Airlines

Sun 2/110:00 amTYS - LAX

1 stop10h 29mMultiple Airlines

Deal found 12/23

$226

Fri 1/3011:59 pmLAX - TYS

1 stop14h 10mMultiple Airlines

Sun 2/110:00 amTYS - LAX

1 stop10h 29mMultiple Airlines

Deal found 12/23

$238

Fri 1/3011:59 pmLAX - TYS

1 stop14h 10mMultiple Airlines

Sat 2/75:59 pmTYS - LAX

1 stop31h 57mMultiple Airlines

Deal found 12/24

$268

One-way flights from Irvine to Knoxville
Search for one-way flight options from Irvine to Knoxville. Find affordable one-way fares based on user searches. Data last updated December 25, 2025.

Wed 1/2811:51 amLAX - TYS

1 stop27h 48mMultiple Airlines

Deal found 12/23

$109

Fri 1/306:30 amLAX - TYS

1 stop6h 00mFrontier

Deal found 12/23

$126

Fri 1/307:07 pmLAX - TYS

2 stops34h 32mMultiple Airlines

Deal found 12/23

$134

Mon 1/56:34 amLAX - TYS

1 stop6h 17mFrontier

Deal found 12/23

$142

Sun 2/229:09 pmLAX - TYS

1 stop22h 52mMultiple Airlines

Deal found 12/22

$150

Tue 1/69:20 pmLAX - TYS

2 stops42h 19mMultiple Airlines

Deal found 12/23

$175

Sun 1/48:58 pmLAX - TYS

1 stop15h 53mFrontier

Deal found 12/23

$197

Sun 2/156:00 amLAX - TYS

1 stop9h 13mAmerican Airlines

Deal found 12/25

$219

Find flight deals from Irvine to Knoxville

Most accurate provider	Mytrip 3 stars
Most trusted provider	Mytrip 3 stars
Round-trip from	$217 (Frontier)
One-way from	$109 (Kiwi.com)
Popular in	January
Cheapest in	August
Average price	$568

Provider with most accurate pricing for Los Angeles-Knoxville McGhee Tyson flight deals.

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Provider most trusted by Cheapflights users for Los Angeles-Knoxville McGhee Tyson flights.

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From Irvine to Knoxville McGhee Tyson

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One-way flight from Irvine to Knoxville McGhee Tyson

Search Deals

Highest demand for flights based on searches. 9% potential increase in price ($51 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($13 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in December 2025

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Tue 2/3

7:07 pm-3:57 pm

2 stops17h 50m

Knoxville McGhee Tyson

Fri 2/6

7:35 am-3:12 pm

1 stop10h 37m

$261

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Fri 2/20

11:11 am-11:01 pm

1 stop8h 50m

Knoxville McGhee Tyson

Sun 2/22

8:30 am-5:54 pm

1 stop12h 24m

$267

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 1/7

3:42 pm-6:39 pm

1 stop23h 57m

Knoxville McGhee Tyson

Sat 1/10

11:59 am-10:56 pm

1 stop13h 57m

$273

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Tue 2/3

7:30 am-6:11 pm

1 stop7h 41m

Knoxville McGhee Tyson

Tue 2/10

1:00 pm-6:51 pm

1 stop8h 51m

$277

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 2/11

4:40 pm-5:52 pm

1 stop22h 12m

Knoxville McGhee Tyson

Mon 2/16

9:36 pm-7:15 am

2 stops36h 39m

$279

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 2/18

1:05 am-10:10 pm

2 stops18h 05m

Knoxville McGhee Tyson

Mon 2/23

1:40 pm-8:15 am

1 stop21h 35m

$283

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 1/28

8:00 am-8:47 pm

1 stop9h 47m

Knoxville McGhee Tyson

Thu 1/29

1:00 pm-9:00 pm

1 stop11h 00m

$304

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Tue 2/3

5:00 am-3:14 pm

1 stop7h 14m

Knoxville McGhee Tyson

Fri 2/6

9:05 am-2:35 pm

1 stop8h 30m

$357

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Wed 12/31

1:30 pm-11:13 pm

1 stop6h 43m

Knoxville McGhee Tyson

Wed 1/7

6:10 pm-10:57 pm

1 stop7h 47m

$358

Los AngelesKnoxville

LAX - TYS

LAXTYS

Los Angeles

Thu 2/19

6:00 am-5:11 pm

1 stop8h 11m

Knoxville McGhee Tyson

Sun 2/22

4:30 pm-9:57 pm

1 stop8h 27m

$384

Flights are sorted by cheapest round-trip flights first.

Deals found on 12/23

Showing 1-10 of 18 results

Best time to book a flight from Irvine to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Knoxville

How far ahead should I book a flight from Irvine to Knoxville?

To ensure you get the cheapest price possible for a flight from Irvine to Knoxville, you should look to book at least 73 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Irvine to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $42). Flying from Irvine to Knoxville in June is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from IR9 to TYS?

One of the essential ways to save on airfare from Irvine to Knoxville is to remain as flexible as possible. Flights that are in the afternoon tend to be the most expensive. A flight in the evening could potentially save you up to 5% on airfare.

What is the cheapest day to fly from Irvine to Knoxville?

Travelers seeking maximum savings on their Irvine to Knoxville flight should consider departing on Saturday afternoons when fares are most often at their lowest. Monday afternoons flights should be avoided if possible as fares are typically the most expensive at this time.

How much does it cost to fly round-trip from Irvine to Knoxville?

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Irvine to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Delta

7.9

Good

8,011 reviews

Reviews

1 / 20

10.0

Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Delta

7.9

Good

8,011 reviews

Delta

7.9

Good

8,011 reviews

Reviews

1 / 20

10.0

Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

United Airlines

7.4

Good

9,114 reviews

Delta

7.9

Good

8,011 reviews

Reviews

1 / 20

10.0

Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

American Airlines

7.2

Good

11,056 reviews

Delta

7.9

Good

8,011 reviews

Reviews

1 / 20

10.0

Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Frontier

5.8

Fair

3,069 reviews

Delta

7.9

Good

8,011 reviews

Reviews

1 / 20

10.0

Excellent

Michael,Sep 2023

SMF - ATL

Not sufficient leg room and three seats are very tigh.t on 737 in economy main cabin

Related info for your journey

What airport do you fly into for flights to Knoxville from Irvine?
For a flight from Irvine to Knoxville, you will be flying into McGhee Tyson. Knoxville McGhee Tyson (TYS) is just 11.3 mi from the center of the city. McGhee Tyson is the only Knoxville airport and it handles 0 inbound flights from Irvine per day. 4 airlines have flights to Knoxville McGhee Tyson from Irvine on a regular basis.
How long is the flight from Irvine to Knoxville?
Delta can get you from Irvine to Knoxville in just under 7h 41m. Your travel time can differ by up to . Airlines will cover a distance of 1944 mi.
What are the cheapest airlines to fly from Irvine to Knoxville one-way?
One-way options have recently been found by users for as low as $85 on Frontier. Other airlines that offer cheap prices include Delta from $178 and United Airlines from $194 one-way.
Can I find deals for flights from Irvine to Knoxville that include hotel bookings?
Yes. In addition to deals on Irvine to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Irvine to Knoxville?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Irvine to Knoxville.
Can I find deals for business class flights from Irvine to Knoxville?
Yes. Cheapflights offers flight deals from Irvine to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.
What is the cheapest month to book a flight from Irvine to Knoxville?
Currently, January is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $42). Flying from Irvine to Knoxville in June is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

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Top 4 airlines flying from Irvine to Knoxville

Airline	Cheapest	Average	Flexibility	On-time
Frontier	Cheapest$144	Average$294	FlexibilityNo cancel fee	On-time62%
United Airlines	Cheapest$239	Average$515	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$261	Average$447	FlexibilityNo cancel fee	On-time71%
Delta	Cheapest$276	Average$415	FlexibilityNo cancel fee	On-timeN/A

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$109+ Cheap flights from Irvine, CA to Knoxville (TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/28. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Irvine to Knoxville with Cheapflights

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Cheapflights Tip: The best prices from Irvine to Knoxville McGhee Tyson are usually found in August or July, booked 73 days in advance, depart on a Saturday or Tuesday and return on a Wednesday

Cheap flight deals from Irvine to Knoxville

Cheapest flights from Irvine to KnoxvilleExplore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.

Find flight deals from Irvine to Knoxville

Keep the following information in mind while searching for Irvine to Knoxville flight deals. Data was last updated December 25, 2025.

Most accurate provider

Most trusted provider

Round-trip from

One-way from

Popular in

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Average price

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Use the filters below to find and compare flights from Irvine to Knoxville that are best for you.

Best time to book a flight from Irvine to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.

Cheapflights Insights

Everything you need to know about your flight from Irvine to Knoxville

How far ahead should I book a flight from Irvine to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Irvine to Knoxville. Price data was last updated on December 19, 2025.

What is the cheapest month to book a flight from Irvine to Knoxville?

What is the cheapest time of day to fly from IR9 to TYS?

Find hourly flight availability from Irvine to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated December 25, 2025.

What is the cheapest day to fly from Irvine to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Irvine to Knoxville. Price data was last updated on December 16, 2024.

How much does it cost to fly round-trip from Irvine to Knoxville?

Reviews of airlines servicing Knoxville

Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Irvine to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

Find useful and relevant information for your journey from Irvine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

What airport do you fly into for flights to Knoxville from Irvine?

How long is the flight from Irvine to Knoxville?

What are the cheapest airlines to fly from Irvine to Knoxville one-way?

Can I find deals for flights from Irvine to Knoxville that include hotel bookings?

How can I find direct flights from Irvine to Knoxville?

Can I find deals for business class flights from Irvine to Knoxville?

What is the cheapest month to book a flight from Irvine to Knoxville?

Traveling to a place near Knoxville?

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Top 4 airlines flying from Irvine to Knoxville

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Cheapest flights from Irvine to Knoxville
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on December 25, 2025.