$95+ Cheap flights from Irvine, CA to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/26. Fares are subject to change and may not be available on all flights or dates of travel.
LAX — TYS
Mar 13 — Mar 201
1 adult, Economy
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Find cheap flights from Irvine to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Irvine to Knoxville
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Cheapest flights from Irvine to KnoxvilleExplore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
Explore the most affordable flight options available from Irvine to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on February 11, 2026.
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/76:15 am
LAX
- TYS
1 stop6h 18m
Frontier
Sun 5/104:28 pm
TYS
- LAX
1 stop10h 43m
Frontier
Deal found 2/9![Frontier logo]()
$211
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/2512:24 pm
LAX
- TYS
1 stop24h 09m
Frontier
Thu 4/304:28 pm
TYS
- LAX
1 stop19h 12m
Frontier
Deal found 2/9![Frontier logo]()
$222
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:15 am
LAX
- TYS
1 stop6h 10m
Frontier
Mon 3/164:20 pm
TYS
- LAX
1 stop10h 56m
Frontier
Deal found 2/9![Frontier logo]()
$228
This Expedia deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
LAX
- TYS
1 stop10h 27m
Frontier
Mon 2/238:13 pm
TYS
- LAX
1 stop30h 05m
Frontier
Deal found 2/10![Frontier logo]()
$232
This Frontier deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:15 am
LAX
- TYS
1 stop6h 13m
Frontier
Mon 4/134:20 pm
TYS
- LAX
1 stop10h 52m
Frontier
Deal found 2/10![Frontier logo]()
$240
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:15 am
LAX
- TYS
1 stop6h 10m
Frontier
Mon 3/94:20 pm
TYS
- LAX
1 stop10h 56m
Frontier
Deal found 2/10![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:12 am
LAX
- TYS
1 stop6h 51m
Multiple Airlines
Wed 3/1810:00 am
TYS
- LAX
1 stop8h 06m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:12 am
LAX
- TYS
1 stop6h 51m
Multiple Airlines
Tue 3/173:00 pm
TYS
- LAX
2 stops19h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$274
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 pm
LAX
- TYS
1 stop21h 33m
Multiple Airlines
Tue 3/173:00 pm
TYS
- LAX
2 stops19h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:15 pm
LAX
- TYS
1 stop16h 19m
Multiple Airlines
Mon 3/168:58 am
TYS
- LAX
2 stops49h 15m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:59 pm
LAX
- TYS
1 stop10h 04m
Multiple Airlines
Mon 3/99:36 pm
TYS
- LAX
2 stops27h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$282
Best flights from Irvine to KnoxvilleDiscover carefully curated flight deals from Irvine to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
Discover carefully curated flight deals from Irvine to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated February 11, 2026.
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 pm
LAX
- TYS
1 stop21h 33m
Multiple Airlines
Tue 3/173:00 pm
TYS
- LAX
2 stops19h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$277
This United Airlines deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/1712:25 am
LAX
- TYS
1 stop6h 54m
United Airlines
Sat 3/217:25 pm
TYS
- LAX
1 stop8h 44m
United Airlines
Deal found 2/7![United Airlines logo]()
$299
This Southwest deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/86:45 am
LAX
- TYS
2 stops9h 55m
Southwest
Wed 4/155:50 pm
TYS
- LAX
1 stop8h 55m
Southwest
Deal found 2/8![Southwest logo]()
$304
This Delta deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/116:00 am
LAX
- TYS
1 stop7h 43m
Delta
Wed 3/185:10 pm
TYS
- LAX
1 stop9h 45m
Delta
Deal found 2/10![Delta logo]()
$309
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:59 pm
LAX
- TYS
1 stop10h 04m
Multiple Airlines
Mon 3/99:36 pm
TYS
- LAX
2 stops27h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$285
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/115:00 am
LAX
- TYS
1 stop7h 02m
United Airlines
Wed 3/187:25 pm
TYS
- LAX
1 stop8h 44m
United Airlines
Deal found 2/10![United Airlines logo]()
$299
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/811:02 pm
LAX
- TYS
1 stop8h 06m
United Airlines
Wed 4/155:48 pm
TYS
- LAX
1 stop7h 56m
United Airlines
Deal found 2/8![United Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/24:07 pm
LAX
- TYS
1 stop28h 20m
Multiple Airlines
Tue 4/72:56 pm
TYS
- LAX
1 stop12h 00m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$310
This United Airlines deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 5/2612:44 pm
LAX
- TYS
1 stop6h 36m
United Airlines
Sat 5/305:57 pm
TYS
- LAX
1 stop9h 02m
United Airlines
Deal found 2/10![United Airlines logo]()
$299
This Kiwi.com deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/148:54 pm
LAX
- TYS
1 stop22h 30m
Multiple Airlines
Tue 5/193:48 pm
TYS
- LAX
2 stops23h 48m
Multiple Airlines
Deal found 2/11![Multiple Airlines logo]()
$351
This United Airlines deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/1612:25 am
LAX
- TYS
1 stop6h 54m
United Airlines
Sat 3/217:25 pm
TYS
- LAX
1 stop8h 44m
United Airlines
Deal found 2/8![United Airlines logo]()
$322
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/301:28 pm
LAX
- TYS
2 stops23h 38m
Multiple Airlines
Fri 4/101:43 pm
TYS
- LAX
1 stop22h 23m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$361
Last-minute flights from Irvine to KnoxvilleDiscover last-minute flight deals from Irvine to Knoxville. Data last updated February 11, 2026 and is based on user searches.
Discover last-minute flight deals from Irvine to Knoxville. Data last updated February 11, 2026 and is based on user searches.
This Expedia deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
LAX
- TYS
1 stop10h 27m
Frontier
Mon 2/238:13 pm
TYS
- LAX
1 stop20h 03m
Frontier
Deal found 2/9![Frontier logo]()
$211
This Expedia deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Expedia is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 2/236:01 am
LAX
- TYS
1 stop10h 17m
Frontier
Fri 2/276:51 pm
TYS
- LAX
1 stop21h 45m
Frontier
Deal found 2/8![Frontier logo]()
$276
This CheapOair deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/262:37 pm
LAX
- TYS
1 stop24h 29m
Frontier
Mon 3/28:13 pm
TYS
- LAX
1 stop28h 02m
Frontier
Deal found 2/10![Frontier logo]()
$222
This Priceline deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/66:15 am
LAX
- TYS
1 stop6h 10m
Frontier
Mon 3/94:20 pm
TYS
- LAX
1 stop10h 56m
Frontier
Deal found 2/10![Frontier logo]()
$250
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/611:59 pm
LAX
- TYS
1 stop10h 04m
Multiple Airlines
Mon 3/99:36 pm
TYS
- LAX
2 stops27h 58m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$282
This Priceline deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:15 am
LAX
- TYS
1 stop6h 10m
Frontier
Mon 3/164:20 pm
TYS
- LAX
1 stop10h 56m
Frontier
Deal found 2/9![Frontier logo]()
$228
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/910:15 pm
LAX
- TYS
1 stop16h 19m
Multiple Airlines
Mon 3/168:58 am
TYS
- LAX
2 stops49h 15m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$281
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 pm
LAX
- TYS
1 stop21h 33m
Multiple Airlines
Tue 3/173:00 pm
TYS
- LAX
2 stops19h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$277
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:12 am
LAX
- TYS
1 stop6h 51m
Multiple Airlines
Wed 3/1810:00 am
TYS
- LAX
1 stop8h 06m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$269
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 3/119:12 am
LAX
- TYS
1 stop6h 51m
Multiple Airlines
Tue 3/173:00 pm
TYS
- LAX
2 stops19h 13m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$274
One-way flights from Irvine to KnoxvilleSearch for one-way flight options from Irvine to Knoxville. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
Search for one-way flight options from Irvine to Knoxville. Find affordable one-way fares based on user searches. Data last updated February 11, 2026.
This Frontier deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/276:00 am
LAX
- TYS
1 stop9h 06m
Frontier
Deal found 2/9![Frontier logo]()
$95
This CheapOair deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 4/128:58 pm
LAX
- TYS
1 stop15h 30m
Frontier
Deal found 2/9![Frontier logo]()
$107
This Frontier deal was found by Cheapflights users on 2/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/96:15 am
LAX
- TYS
1 stop6h 10m
Frontier
Deal found 2/8![Frontier logo]()
$109
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 2/206:00 am
LAX
- TYS
1 stop10h 27m
Frontier
Deal found 2/11![Frontier logo]()
$122
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/66:15 am
LAX
- TYS
1 stop6h 13m
Frontier
Deal found 2/11![Frontier logo]()
$125
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:30 pm
LAX
- TYS
1 stop21h 33m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$131
This CheapOair deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure CheapOair is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/28:58 pm
LAX
- TYS
1 stop15h 30m
Frontier
Deal found 2/11![Frontier logo]()
$137
This Kiwi.com deal was found by Cheapflights users on 2/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/279:12 am
LAX
- TYS
1 stop10h 39m
Multiple Airlines
Deal found 2/7![Multiple Airlines logo]()
$140
This Kiwi.com deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/19:09 pm
LAX
- TYS
1 stop22h 45m
Multiple Airlines
Deal found 2/9![Multiple Airlines logo]()
$141
This Kiwi.com deal was found by Cheapflights users on 2/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 2/199:16 pm
LAX
- TYS
1 stop22h 45m
Multiple Airlines
Deal found 2/10![Multiple Airlines logo]()
$142
This Frontier deal was found by Cheapflights users on 2/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/106:15 am
LAX
- TYS
1 stop6h 13m
Frontier
Deal found 2/11![Frontier logo]()
$145
This Delta deal was found by Cheapflights users on 2/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/3111:30 pm
LAX
- TYS
1 stop8h 01m
Delta
Deal found 2/9![Delta logo]()
$150
Find flight deals from Irvine to Knoxville
Keep the following information in mind while searching for Irvine to Knoxville flight deals. Data was last updated February 11, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $211 (Expedia) |
One-way from | $95 (Frontier) |
Popular in | March |
Cheapest in | August |
Average price | $436 |
Cheapflights Fare Finder
Customize your flight search to find flights from Irvine to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
Use the filters below to find and compare flights from Irvine to Knoxville that are best for you.
Fly from
Irvine
Fly to
Knoxville
Route
Depart
Return
Price
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Tue 3/10
6:30 pm-7:03 pm
1 stop21h 33m
Knoxville McGhee Tyson
Tue 3/17
3:00 pm-7:13 am
2 stops19h 13m
$277
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Fri 3/6
11:59 pm-1:03 pm
1 stop10h 04m
Knoxville McGhee Tyson
Mon 3/9
9:36 pm-10:34 pm
2 stops27h 58m
$285
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Tue 3/17
12:25 am-10:19 am
1 stop6h 54m
Knoxville McGhee Tyson
Sat 3/21
7:25 pm-1:09 am
1 stop8h 44m
$299
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 3/11
5:00 am-3:02 pm
1 stop7h 02m
Knoxville McGhee Tyson
Wed 3/18
7:25 pm-1:09 am
1 stop8h 44m
$299
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 4/8
11:02 pm-10:08 am
1 stop8h 06m
Knoxville McGhee Tyson
Wed 4/15
5:48 pm-10:44 pm
1 stop7h 56m
$299
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Tue 5/26
12:44 pm-10:20 pm
1 stop6h 36m
Knoxville McGhee Tyson
Sat 5/30
5:57 pm-11:59 pm
1 stop9h 02m
$299
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 4/8
6:45 am-7:40 pm
2 stops9h 55m
Knoxville McGhee Tyson
Wed 4/15
5:50 pm-11:45 pm
1 stop8h 55m
$304
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Wed 3/11
6:00 am-4:43 pm
1 stop7h 43m
Knoxville McGhee Tyson
Wed 3/18
5:10 pm-11:55 pm
1 stop9h 45m
$309
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Thu 4/2
4:07 pm-11:27 pm
1 stop28h 20m
Knoxville McGhee Tyson
Tue 4/7
2:56 pm-11:56 pm
1 stop12h 00m
$310
Los AngelesKnoxville
LAX - TYS
LAXTYS
Los Angeles
Mon 3/16
12:25 am-10:19 am
1 stop6h 54m
Knoxville McGhee Tyson
Sat 3/21
7:25 pm-1:09 am
1 stop8h 44m
$322
Showing 1-10 of 23 results
Best time to book a flight from Irvine to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Irvine with our price prediction graph.
LAX-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Irvine to Knoxville
IR9-TYS
LAX-TYS
How far ahead should I book a flight from Irvine to Knoxville?
Use this chart to determine the optimal time to book a round-trip flight from Irvine to Knoxville. Price data was last updated on February 6, 2026.
To ensure you get the cheapest price possible for a flight from Irvine to Knoxville, you should look to book at least 73 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
What is the cheapest month to book a flight from Irvine to Knoxville?
Currently, September is the cheapest month in which you can book a flight from Irvine to Knoxville (average of $191). Flying from Irvine to Knoxville in June is currently the most expensive (average of $288). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated February 11, 2026.
Read reviews from past customers who have flown Delta, United Airlines, and American Airlines from Irvine to Knoxville. Users can see the overall rating for each airline as well as how each is rated in terms of entertainment options, comfort, food, crew/service, and boarding process.
Comfort
7.9
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Comfort
7.9
Food
7.2
Overall
7.9
Boarding
8.1
Entertainment
7.8
Crew
8.5
Reviews
1 / 20
10.0
ExcellentMichael,Sep 2023
SMF - ATL
Related info for your journey
Find useful and relevant information for your journey from Irvine to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy
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Alternative routes for Irvine to Knoxville
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Complete your trip
Complete your trip to Knoxville by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Irvine to Knoxville by cabin class
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Other flights to Knoxville
Explore flights to Knoxville departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on February 11, 2026.
Irvine and Knoxville flights
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Top 4 airlines flying from Irvine to Knoxville
Discover the top 4 airlines that operate flights from Irvine to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated February 11, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$142 | Average$296 | FlexibilityNo cancel fee | On-time62% | |
| Cheapest$174 | Average$398 | FlexibilityNo cancel fee | On-timeN/A | |
| Cheapest$239 | Average$488 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$258 | Average$443 | FlexibilityNo cancel fee | On-time71% |