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Knoxville

$170+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/15. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
Apr 9 — Apr 161
Thu 4/9
Thu 4/16
1 adult, Economy
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Cheap flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on March 10, 2026.

This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 6/87:05 pm
GNV
-
TYS
1 stop4h 41m
Delta
Fri 6/125:30 am
TYS
-
GNV
1 stop3h 53m
Delta
Deal found 3/6$397
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:10 pm
GNV
-
TYS
1 stop5h 05m
Delta
Mon 8/35:30 am
TYS
-
GNV
1 stop3h 53m
Delta
Deal found 3/7$417
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/237:45 pm
GNV
-
TYS
1 stop4h 05m
American Airlines
Sat 3/285:00 am
TYS
-
GNV
1 stop6h 04m
American Airlines
Deal found 3/9$427
This American Airlines deal was found by Cheapflights users on 3/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/246:00 am
GNV
-
TYS
2 stops9h 30m
American Airlines
Sat 3/285:00 am
TYS
-
GNV
1 stop6h 04m
American Airlines
Deal found 3/9$432
This Delta deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/26:00 am
GNV
-
TYS
1 stop3h 16m
Delta
Thu 4/96:38 pm
TYS
-
GNV
1 stop3h 59m
Delta
Deal found 3/5$437
This Delta deal was found by Cheapflights users on 3/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 3/226:00 am
GNV
-
TYS
1 stop3h 16m
Delta
Thu 3/265:40 am
TYS
-
GNV
1 stop3h 49m
Delta
Deal found 3/7$508
This American Airlines deal was found by Cheapflights users on 3/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/27:45 pm
GNV
-
TYS
1 stop4h 05m
American Airlines
Thu 4/93:58 pm
TYS
-
GNV
2 stops8h 01m
American Airlines
Deal found 3/5$560
This Delta deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 3/67:00 pm
GNV
-
TYS
1 stop4h 52m
Delta
Mon 3/96:38 pm
TYS
-
GNV
1 stop3h 59m
Delta
Deal found 3/6$567
This American Airlines deal was found by Cheapflights users on 3/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/306:00 am
GNV
-
TYS
2 stops9h 10m
American Airlines
Mon 8/35:00 am
TYS
-
GNV
1 stop4h 02m
American Airlines
Deal found 3/6$602

Find flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated March 10, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$397
(Delta)

One-way from

$170
(American Airlines)

Popular in

February

Cheapest in

January

Average price

$306
Provider with most accurate pricing for Gainesville Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Knoxville McGhee Tyson flights.
Search Deals
From Gainesville Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Gainesville Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 3% potential increase in price ($14 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 6% potential price decrease ($21 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in March 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 6/8

7:05 pm-11:46 pm

1 stop4h 41m

Knoxville McGhee Tyson

Fri 6/12

5:30 am-9:23 am

1 stop3h 53m

$397

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 3/24

7:01 pm-10:48 pm

1 stop3h 47m

Knoxville McGhee Tyson

Sat 3/28

7:02 am-11:04 am

1 stop4h 02m

$427

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 3/23

7:45 pm-11:50 pm

1 stop4h 05m

Knoxville McGhee Tyson

Sat 3/28

5:00 am-11:04 am

1 stop6h 04m

$427
Quickest round-trip

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 4/2

6:00 am-9:16 am

1 stop3h 16m

Knoxville McGhee Tyson

Thu 4/9

6:38 pm-10:37 pm

1 stop3h 59m

$437

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 4/2

7:45 pm-11:50 pm

1 stop4h 05m

Knoxville McGhee Tyson

Thu 4/9

3:58 pm-11:59 pm

2 stops8h 01m

$560

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 6/8

7:32 pm-11:47 pm

1 stop4h 15m

Knoxville McGhee Tyson

Fri 6/12

3:40 pm-11:59 pm

2 stops8h 19m

$632

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 3/13

6:24 am-11:20 am

1 stop4h 56m

Knoxville McGhee Tyson

Sat 3/21

5:00 am-11:04 am

1 stop6h 04m

$1,141
Cheapest one-way

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 4/15

7:59 pm-11:55 pm

1 stop3h 56m

$170
Quickest one-way

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 3/29

6:00 am-9:16 am

1 stop3h 16m

$209

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Fri 3/27

7:00 pm-11:57 pm

1 stop4h 57m

$239

Flights are sorted by cheapest round-trip flights first.

Deals found on 3/7

Showing 1-10 of 12 resultsSorted by cheapest first
1
2

Compare providers for flights from Gainesville to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Knoxville in March.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

What is the cheapest month to book a flight from Gainesville to Knoxville?

Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in March is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated March 10, 2026.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,276 reviews

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,276 reviews
Delta
7.9
Good
8,276 reviews

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.1
Good
11,414 reviews
Delta
7.9
Good
8,276 reviews

Boarding

8.1

Entertainment

7.8

Overall

7.9

Comfort

7.9

Food

7.2

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like Delta and American Airlines fly from Gainesville to Knoxville in about 3h 47m. The time it takes to get you to your destination can typically vary by up to 54m. The distance between Gainesville and Knoxville is about 434 mi. This flight may include one or multiple stops.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is Delta, starting at $228. You may be able to fly from Gainesville to Knoxville for 36% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Knoxville?

    Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in March is currently the most expensive (average of $84). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge

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Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated March 10, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$356FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$422FlexibilityNo cancel feeOn-timeN/A

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