HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$268+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 2/15. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
Feb 26 — Mar 51
Thu 2/26
Thu 3/5
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on January 27, 2026.

This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 pm
GNV
-
TYS
1 stop4h 57m
Delta
Tue 3/175:40 am
TYS
-
GNV
1 stop3h 49m
Delta
Deal found 1/25$307
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
GNV
-
TYS
1 stop5h 17m
Delta
Thu 3/195:40 am
TYS
-
GNV
1 stop3h 49m
Delta
Deal found 1/25$317
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/301:10 pm
GNV
-
TYS
1 stop5h 07m
Delta
Mon 8/37:20 pm
TYS
-
GNV
1 stop3h 10m
Delta
Deal found 1/26$327
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
GNV
-
TYS
1 stop3h 16m
Delta
Mon 3/235:10 pm
TYS
-
GNV
1 stop5h 27m
Delta
Deal found 1/25$357
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
GNV
-
TYS
1 stop5h 17m
Delta
Wed 3/185:10 pm
TYS
-
GNV
1 stop16h 19m
Delta
Deal found 1/25$367
This Delta deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 am
GNV
-
TYS
1 stop3h 24m
Delta
Sat 2/145:35 am
TYS
-
GNV
1 stop3h 49m
Delta
Deal found 1/26$407
This American Airlines deal was found by Cheapflights users on 1/26. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 2/106:00 am
GNV
-
TYS
2 stops7h 54m
American Airlines
Sat 2/142:54 pm
TYS
-
GNV
1 stop4h 26m
American Airlines
Deal found 1/26$412
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
GNV
-
TYS
1 stop3h 16m
Delta
Fri 3/206:38 pm
TYS
-
GNV
1 stop14h 51m
Delta
Deal found 1/25$416
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/167:00 pm
GNV
-
TYS
1 stop16h 17m
Delta
Mon 3/235:10 pm
TYS
-
GNV
1 stop5h 27m
Delta
Deal found 1/25$417
This Delta deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/107:00 pm
GNV
-
TYS
1 stop4h 57m
Delta
Sat 3/215:40 am
TYS
-
GNV
1 stop3h 49m
Delta
Deal found 1/25$437
This American Airlines deal was found by Cheapflights users on 1/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 3/106:00 am
GNV
-
TYS
2 stops9h 30m
American Airlines
Tue 3/1712:22 pm
TYS
-
GNV
1 stop6h 14m
American Airlines
Deal found 1/25$450

Find flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated January 27, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$307
(Delta)

One-way from

$268
(Delta)

Popular in

March

Cheapest in

January

Average price

$228
Provider with most accurate pricing for Gainesville Regional-Knoxville McGhee Tyson flight deals.
Search Deals
Provider most trusted by Cheapflights users for Gainesville Regional-Knoxville McGhee Tyson flights.
Search Deals
From Gainesville Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Gainesville Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 14% potential increase in price ($62 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 4% potential price decrease ($14 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in January 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Gainesville

Fly to

Knoxville

Route

Depart

Return

Price

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 3/11

6:00 am-11:17 am

1 stop5h 17m

Knoxville McGhee Tyson

Tue 3/17

5:40 am-9:29 am

1 stop3h 49m

$307

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 3/11

6:00 am-9:16 am

1 stop3h 16m

Knoxville McGhee Tyson

Thu 3/19

5:40 am-9:29 am

1 stop3h 49m

$317

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 3/10

6:00 am-11:17 am

1 stop5h 17m

Knoxville McGhee Tyson

Thu 3/19

5:40 am-9:29 am

1 stop3h 49m

$317

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 3/10

6:00 am-9:16 am

1 stop3h 16m

Knoxville McGhee Tyson

Mon 3/23

5:10 pm-10:37 pm

1 stop5h 27m

$357

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 2/11

5:00 pm-10:54 pm

1 stop5h 54m

Knoxville McGhee Tyson

Sun 2/15

7:02 am-10:59 am

1 stop3h 57m

$407

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 2/10

6:00 am-9:24 am

1 stop3h 24m

Knoxville McGhee Tyson

Sat 2/14

5:35 am-9:24 am

1 stop3h 49m

$407

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 2/10

6:00 am-1:54 pm

2 stops7h 54m

Knoxville McGhee Tyson

Sat 2/14

2:54 pm-7:20 pm

1 stop4h 26m

$412

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 3/10

6:00 am-9:16 am

1 stop3h 16m

Knoxville McGhee Tyson

Fri 3/20

6:38 pm-9:29 am

1 stop14h 51m

$416

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 3/11

6:00 am-9:16 am

1 stop3h 16m

Knoxville McGhee Tyson

Fri 3/20

5:40 am-4:08 pm

1 stop10h 28m

$416

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 3/11

6:00 am-11:17 am

1 stop5h 17m

Knoxville McGhee Tyson

Sat 3/21

5:40 am-9:29 am

1 stop3h 49m

$437

Flights are sorted by cheapest round-trip flights first.

Deals found on 1/25

Showing 1-10 of 13 results
1
2

Compare providers for flights from Gainesville to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Knoxville in January.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy1 starTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Knoxville flights, users find the pricing of FlightHub to be most consistent on Cheapflights vs. FlightHub Users can find the same prices on Gainesville-Knoxville flight deals on Cheapflights vs. FlightHub >95% of the time. Price accuracy is based on data collected from Gainesville-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Knoxville flights, Cheapflights users trust FlightHub the most. FlightHub has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

What is the cheapest month to book a flight from Gainesville to Knoxville?

Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in May is currently the most expensive (average of $80). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated January 27, 2026.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
8,118 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,197 reviews
Delta
7.9
Good
8,118 reviews

Crew

8.5

Food

7.2

Entertainment

7.8

Overall

7.9

Boarding

8.1

Comfort

7.9

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like Delta fly from Gainesville to Knoxville in about 5h 17m. The time it takes to get you to your destination can typically vary by up to . The distance between Gainesville and Knoxville is about 434 mi.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is Delta, starting at $228. You may be able to fly from Gainesville to Knoxville for 37% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Knoxville?

    Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in May is currently the most expensive (average of $80). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Cherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Orlando to Nashville flights
Fort Lauderdale to Nashville flights
Tampa to Nashville flights
Miami to Nashville flights
West Palm Beach to Nashville flights
Fort Myers to Nashville flights
Jacksonville to Nashville flights
Miami to Knoxville flights
Orlando to Knoxville flights
Fort Lauderdale to Knoxville flights
Sarasota to Nashville flights
Tampa to Knoxville flights
Orlando to Memphis flights
Tampa to Memphis flights
Orlando to Chattanooga flights
Miami to Memphis flights
Panama City to Nashville flights
West Palm Beach to Knoxville flights
Pensacola to Nashville flights
Orlando Sanford Intl to Knoxville flights
Fort Myers to Knoxville flights
Tallahassee to Nashville flights
West Palm Beach to Chattanooga flights
St Petersburg to Knoxville flights
Tampa to Chattanooga flights
Sarasota to Knoxville flights
Jacksonville to Memphis flights
Fort Lauderdale to Memphis flights
Jacksonville to Knoxville flights
West Palm Beach to Memphis flights
Gainesville to Nashville flights
Pensacola to Knoxville flights
Daytona Beach to Nashville flights
Fort Myers to Memphis flights
Tallahassee to Knoxville flights
Miami to Chattanooga flights
Melbourne to Nashville flights
Pensacola to Chattanooga flights
Sarasota to Chattanooga flights
Fort Myers to Chattanooga flights
Fort Lauderdale to Chattanooga flights
Valparaiso to Nashville flights
Sarasota to Memphis flights
Jacksonville to Chattanooga flights
Fort Lauderdale to Blountville flights
Key West to Nashville flights
Daytona Beach to Knoxville flights
Pensacola to Memphis flights
Tallahassee to Memphis flights

Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated January 27, 2026.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$378FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$402FlexibilityNo cancel feeOn-timeN/A

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.