HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Knoxville

$228+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/9. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
oct. 11 — oct. 181
sáb. 10/11
sáb. 10/18
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Gainesville to Knoxville with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated septiembre 11, 2025.

Round-trip from

$234
(American Airlines)

One-way from

$228
(American Airlines)

Popular in

November

Cheapest in

August

Average price

$363
From Gainesville Regional to Knoxville McGhee Tyson
Search Deals
One-way flight from Gainesville Regional to Knoxville McGhee Tyson
Search Deals
Highest demand for flights based on searches. 27% potential increase in price ($174 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 5% potential price decrease ($27 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in September 2025
Search Deals

Find flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on septiembre 11, 2025.

This American Airlines deal was found by Cheapflights users on 9/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
lun. 9/296:00 amGNV - TYS
1 stop3h 56mAmerican Airlines
lun. 10/68:37 pmTYS - GNV
1 stop3h 40mAmerican Airlines
Deal found 9/8$229
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/167:06 pmGNV - TYS
1 stop4h 38mDelta
mar. 9/235:45 amTYS - GNV
1 stop3h 40mDelta
Deal found 9/9$254
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mar. 9/166:13 amGNV - TYS
2 stops7h 30mAmerican Airlines
mar. 9/235:05 amTYS - GNV
1 stop5h 16mAmerican Airlines
Deal found 9/9$259
This Delta deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/247:06 pmGNV - TYS
1 stop4h 38mDelta
dom. 9/285:45 amTYS - GNV
1 stop3h 30mDelta
Deal found 9/9$369
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sáb. 10/256:30 amGNV - TYS
1 stop4h 01mAmerican Airlines
lun. 10/278:37 pmTYS - GNV
1 stop3h 40mAmerican Airlines
Deal found 9/10$404
This Delta deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 12/1010:11 amGNV - TYS
1 stop4h 40mDelta
dom. 12/145:25 amTYS - GNV
1 stop3h 59mDelta
Deal found 9/10$423
This American Airlines deal was found by Cheapflights users on 9/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
mié. 9/246:13 amGNV - TYS
2 stops7h 30mAmerican Airlines
dom. 9/285:05 amTYS - GNV
1 stop3h 45mAmerican Airlines
Deal found 9/9$466
This American Airlines deal was found by Cheapflights users on 9/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
jue. 9/256:13 amGNV - TYS
2 stops7h 41mAmerican Airlines
lun. 9/293:09 pmTYS - GNV
2 stops8h 50mAmerican Airlines
Deal found 9/10$471

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Gainesville

Fly to

Knoxville

Route

Depart

Return

Price

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

lun. 9/29

4:43 pm-11:03 pm

1 stop6h 20m

Knoxville McGhee Tyson

lun. 10/6

8:37 pm-12:17 am

1 stop3h 40m

$234

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

sáb. 10/25

6:30 am-10:31 am

1 stop4h 01m

Knoxville McGhee Tyson

lun. 10/27

8:37 pm-12:17 am

1 stop3h 40m

$404

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

vie. 9/26

4:43 pm-11:03 pm

1 stop6h 20m

Knoxville McGhee Tyson

mar. 9/30

5:05 am-10:21 am

1 stop5h 16m

$411

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

mié. 12/10

10:11 am-2:51 pm

1 stop4h 40m

Knoxville McGhee Tyson

dom. 12/14

5:25 am-9:24 am

1 stop3h 59m

$423

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

jue. 9/25

6:13 am-1:54 pm

2 stops7h 41m

Knoxville McGhee Tyson

lun. 9/29

3:09 pm-11:59 pm

2 stops8h 50m

$471

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

jue. 12/11

4:53 pm-11:57 pm

1 stop7h 04m

Knoxville McGhee Tyson

dom. 12/14

5:05 am-10:56 am

1 stop5h 51m

$483

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

mié. 12/10

6:00 am-2:00 pm

2 stops8h 00m

Knoxville McGhee Tyson

dom. 12/14

5:05 am-10:56 am

1 stop5h 51m

$488

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

jue. 10/9

6:04 am-9:00 am

1 stop2h 56m

$228

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

dom. 12/7

4:53 pm-11:57 pm

1 stop7h 04m

$228

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

mar. 11/11

3:46 pm-7:00 pm

1 stop3h 14m

$228

Flights are sorted by cheapest round-trip flights first.

Deals found on 9/9

Showing 1-10 of 19 results
1
2

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

What is the cheapest month to book a flight from Gainesville to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $294). Flying from Gainesville to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to TYS?

Find hourly flight availability from Gainesville to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated septiembre 11, 2025.

It’s typically best to fly out from Gainesville to Knoxville in the afternoon. Doing so could potentially save you 33% on the flight price compared to flying at noon, which is usually more expensive.

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated septiembre 11, 2025.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,960 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,960 reviews

Entertainment

7.9

Food

7.3

Overall

8.0

Comfort

7.9

Crew

8.5

Boarding

8.2

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like American Airlines fly from Gainesville to Knoxville in about 6h 20m. The time it takes to get you to your destination can typically vary by up to . The distance between Gainesville and Knoxville is about 434 mi.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is Delta. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is American Airlines, starting at $313. You may be able to fly from Gainesville to Knoxville for 51% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $294). Flying from Gainesville to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Alcoa
Oak Ridge
Murphy

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Gainesville to Knoxville

See prices for flight routes from nearby airports that may be better suited for you.
Fort Lauderdale to Nashville flights
Miami to Nashville flights
Orlando to Nashville flights
Tampa to Nashville flights
Jacksonville to Nashville flights
West Palm Beach to Nashville flights
Fort Lauderdale to Knoxville flights
Fort Myers to Nashville flights
Orlando to Memphis flights
Miami to Knoxville flights
Orlando Sanford Intl to Knoxville flights
Tampa to Knoxville flights
Sarasota to Nashville flights
Orlando to Knoxville flights
St Petersburg to Knoxville flights
Tampa to Memphis flights
Fort Lauderdale to Chattanooga flights
Pensacola to Nashville flights
Jacksonville to Memphis flights
Fort Myers to Knoxville flights
Tampa to Chattanooga flights
Miami to Memphis flights
Panama City to Nashville flights
Orlando to Chattanooga flights
West Palm Beach to Knoxville flights
Fort Lauderdale to Memphis flights
Tallahassee to Nashville flights
Tampa to Blountville flights
Fort Myers to Memphis flights
Sarasota to Knoxville flights
Daytona Beach to Nashville flights
Pensacola to Knoxville flights
Miami to Chattanooga flights
Gainesville to Nashville flights
Jacksonville to Knoxville flights
Jacksonville to Chattanooga flights
Valparaiso to Nashville flights
Pensacola to Memphis flights
Daytona Beach to Memphis flights
West Palm Beach to Chattanooga flights
West Palm Beach to Memphis flights
Sarasota to Chattanooga flights
Gainesville to Memphis flights
Sarasota to Memphis flights
Melbourne to Nashville flights
Tallahassee to Knoxville flights
Daytona Beach to Knoxville flights
Panama City to Knoxville flights
Melbourne to Knoxville flights
Orlando to Blountville flights

Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated septiembre 11, 2025.
AirlineCheapestAverageFlexibilityOn-time
DeltaCheapest$228Average$422FlexibilityNo cancel feeOn-timeN/A
American AirlinesCheapest$313Average$613FlexibilityNo cancel feeOn-time71%

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.