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$189+ Cheap flights from Gainesville to Knoxville (GNV - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 1/27. Fares are subject to change and may not be available on all flights or dates of travel.
GNV — TYS
Nov 28 — Dec 51
Fri 11/28
Fri 12/5
1 adult, Economy
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Cheap flight deals from Gainesville to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Gainesville (GNV) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated October 29, 2025.

Most accurate provider

eDreams
3 stars

Most trusted provider

eDreams
3 stars

Round-trip from

$229
(American Airlines)

One-way from

$189
(Delta)

Popular in

November

Cheapest in

September

Average price

$402
Provider with most accurate pricing for Gainesville Regional-Knoxville McGhee Tyson flight deals.
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Provider most trusted by Cheapflights users for Gainesville Regional-Knoxville McGhee Tyson flights.
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From Gainesville Regional to Knoxville McGhee Tyson
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One-way flight from Gainesville Regional to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 27% potential increase in price ($165 potential increase over avg. RT price).
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Cheapest flight prices on average. 6% potential price decrease ($28 potential savings vs. average RT price).
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Average for round-trip flights in October 2025
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Find flight deals from Gainesville to Knoxville

Cheapest flights from Gainesville to Knoxville
Explore the most affordable flight options available from Gainesville to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on October 29, 2025.

This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:40 pmGNV - TYS
1 stop4h 15mAmerican Airlines
Sun 12/75:03 pmTYS - GNV
1 stop6h 55mAmerican Airlines
Deal found 10/27$229
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/36:00 amGNV - TYS
2 stops9h 14mAmerican Airlines
Mon 12/83:14 pmTYS - GNV
2 stops8h 44mAmerican Airlines
Deal found 10/27$333
This American Airlines deal was found by Cheapflights users on 10/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 11/66:00 amGNV - TYS
2 stops6h 59mAmerican Airlines
Tue 11/116:05 amTYS - GNV
1 stop4h 21mAmerican Airlines
Deal found 10/28$404
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/46:00 amGNV - TYS
2 stops8h 29mAmerican Airlines
Sun 12/75:03 pmTYS - GNV
1 stop6h 55mAmerican Airlines
Deal found 10/27$409
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/73:41 pmGNV - TYS
1 stop4h 24mDelta
Mon 12/85:40 amTYS - GNV
1 stop3h 45mDelta
Deal found 10/27$417
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 12/74:53 pmGNV - TYS
1 stop7h 04mAmerican Airlines
Mon 12/83:14 pmTYS - GNV
2 stops8h 44mAmerican Airlines
Deal found 10/27$422
This Delta deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/121:37 pmGNV - TYS
1 stop5h 25mDelta
Sun 11/165:35 amTYS - GNV
1 stop3h 51mDelta
Deal found 10/27$486
This American Airlines deal was found by Cheapflights users on 10/27. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/126:00 amGNV - TYS
2 stops9h 07mAmerican Airlines
Sun 11/166:30 amTYS - GNV
1 stop4h 20mAmerican Airlines
Deal found 10/27$494

Cheapflights Fare Finder

 
Customize your flight search to find flights from Gainesville to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
Use the filters below to find and compare flights from Gainesville to Knoxville that are best for you.

Fly from

Gainesville

Fly to

Knoxville

Route

Depart

Return

Price

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Thu 12/4

8:00 pm-11:57 pm

1 stop3h 57m

Knoxville McGhee Tyson

Sun 12/7

5:03 pm-11:58 pm

1 stop6h 55m

$229

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 12/3

6:40 pm-10:55 pm

1 stop4h 15m

Knoxville McGhee Tyson

Mon 12/8

7:23 pm-11:39 pm

1 stop4h 16m

$229

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 12/3

6:40 pm-10:55 pm

1 stop4h 15m

Knoxville McGhee Tyson

Sun 12/7

5:03 pm-11:58 pm

1 stop6h 55m

$229

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Mon 12/15

7:04 pm-11:28 pm

1 stop4h 24m

Knoxville McGhee Tyson

Fri 12/19

8:35 am-12:53 pm

1 stop4h 18m

$417

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 12/7

3:41 pm-8:05 pm

1 stop4h 24m

Knoxville McGhee Tyson

Mon 12/8

5:40 am-9:25 am

1 stop3h 45m

$417

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Sun 12/7

4:53 pm-11:57 pm

1 stop7h 04m

Knoxville McGhee Tyson

Mon 12/8

3:14 pm-11:58 pm

2 stops8h 44m

$422

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 11/12

1:37 pm-7:02 pm

1 stop5h 25m

Knoxville McGhee Tyson

Sun 11/16

5:35 am-9:26 am

1 stop3h 51m

$486

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 1/27

10:11 am-1:52 pm

1 stop3h 41m

$189

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Tue 1/27

5:00 pm-10:54 pm

1 stop5h 54m

$189

GainesvilleKnoxville

GNV - TYS

GNVTYS

Gainesville Regional

Wed 1/28

10:11 am-3:21 pm

1 stop5h 10m

$189

Flights are sorted by cheapest round-trip flights first.

Deals found on 10/27

Showing 1-10 of 16 results
1
2

Compare providers for flights from Gainesville to Knoxville

Provider information is updated monthly. Please note that these providers often have deals for this flight, but the availability may vary on a day-by-day basis on Cheapflights.
Use the table below to compare price accuracy, trust ratings, and cancellation policies for each provider offering flight deals from Gainesville to Knoxville in October.
ProviderPrice AccuracyTrust Score*
ExpediaPrice Accuracy2 starsTrust Score*3 stars
FlightHubPrice Accuracy3 starsTrust Score*1 star
eDreamsPrice Accuracy3 starsTrust Score*3 stars

*The Trust Score is based on feedback from users after their booking experience. It measures overall satisfaction, helping us identify issues like hidden fees, problems during the ticketing process, and the quality of customer service. This score is our best indicator of the provider's quality and reliability.

  • Most accurate provider: When it comes to deals on Gainesville-Knoxville flights, users find the pricing of eDreams to be most consistent on Cheapflights vs. eDreams Users can find the same prices on Gainesville-Knoxville flight deals on Cheapflights vs. eDreams >95% of the time. Price accuracy is based on data collected from Gainesville-Knoxville flight searches over the past month and is updated monthly.
  • Most trusted provider: When it comes to deals on Gainesville-Knoxville flights, Cheapflights users trust eDreams the most. eDreams has received a user feedback score of 3 out of 3 stars (3 being the best), meaning they have been trusted the most by Cheapflights users looking for Gainesville-Knoxville flight deals. Provider user feedback score is based on Cheapflights searches over the past month and is updated monthly.

Best time to book a flight from Gainesville to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Gainesville with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Gainesville to Knoxville

What is the cheapest month to book a flight from Gainesville to Knoxville?

Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in May is currently the most expensive (average of $80). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from GNV to TYS?

Find hourly flight availability from Gainesville to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated October 29, 2025.

It’s typically best to fly out from Gainesville to Knoxville in the evening. Doing so could potentially save you 43% on the flight price compared to flying at noon, which is usually more expensive.

How much does it cost to fly round-trip from Gainesville to Knoxville?

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated October 29, 2025.
Read through reviews of airlines operating flights from Gainesville to Knoxville, such as Delta and American Airlines. Reviews also offer insight into each airline's entertainment options, comfort, food, crew/service, and boarding process.
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
7.9
Good
7,994 reviews
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
11,032 reviews
Delta
7.9
Good
7,994 reviews

Comfort

7.9

Overall

7.9

Boarding

8.2

Food

7.3

Entertainment

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Gainesville to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • How long is the flight from Gainesville to Knoxville?

    Airlines like American Airlines fly from Gainesville to Knoxville in about 3h 57m. The time it takes to get you to your destination can typically vary by up to . The distance between Gainesville and Knoxville is about 434 mi.

  • What are the cheapest airlines flying from Gainesville to Knoxville round-trip?

    Our cheapest airline available from Gainesville to Knoxville is American Airlines. Our recent data shows that you can find tickets from as low as $228 on this airline. An additional option worth looking into is Delta, starting at $228. You may be able to fly from Gainesville to Knoxville for 48% less than the average price by searching for these airlines.

  • Can I find deals for flights from Gainesville to Knoxville that include hotel bookings?

    Yes. In addition to deals on Gainesville to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Gainesville to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Gainesville to Knoxville.

  • Can I find deals for business class flights from Gainesville to Knoxville?

    Yes. Cheapflights offers flight deals from Gainesville to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Gainesville to Knoxville?

    Currently, September is the cheapest month in which you can book a flight from Gainesville to Knoxville (average of $47). Flying from Gainesville to Knoxville in May is currently the most expensive (average of $80). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Knoxville?

Book flights to Knoxville if you plan to visit one of these locations
Morristown
Cherokee
Crossville
Corbin
Bryson City
Alcoa
Oak Ridge
Murphy

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Top 2 airlines flying from Gainesville to Knoxville

Discover the top 2 airlines that operate flights from Gainesville to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated October 29, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$228Average$495FlexibilityNo cancel feeOn-time71%
DeltaCheapest$228Average$402FlexibilityNo cancel feeOn-timeN/A

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