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$182+ Cheap flights from Fort Myers to Knoxville (RSW - TYS)

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 6/19. Fares are subject to change and may not be available on all flights or dates of travel.
RSW — TYS
Jun 17 — Jun 241
Tue 6/17
Tue 6/24
1 adult, Economy
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Cheapflights Tip: The best prices from Fort Myers SW Florida Intl to Knoxville McGhee Tyson are usually found in September or March, booked 72 days in advance, depart on a Wednesday or Saturday and return on a Wednesday

Cheap flight deals from Fort Myers to Knoxville

Discover tips and strategies to find the most affordable flight options for your journey from Fort Myers (RSW) to Knoxville (TYS). Learn about various techniques such as flexible date searches, comparing prices across and setting up price alerts. Use these methods to find the cheapest flights available for your travel needs. Data last updated June 12, 2025.

Round-trip from

$249
(Delta)

One-way from

$182
(Mytrip)

Popular in

April

Cheapest in

September

Average price

$368
From Fort Myers SW Florida Intl to Knoxville McGhee Tyson
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One-way flight from Fort Myers SW Florida Intl to Knoxville McGhee Tyson
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Highest demand for flights based on searches. 5% potential increase in price ($17 potential increase over avg. RT price).
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Cheapest flight prices on average. 3% potential price decrease ($10 potential savings vs. average RT price).
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Average for round-trip flights in June 2025
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Find flight deals from Fort Myers to Knoxville

Cheapest flights from Fort Myers to Knoxville
Explore the most affordable flight options available from Fort Myers to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on June 12, 2025.

This Delta deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/115:45 pmRSW - TYS
1 stop6h 14mDelta
Thu 7/247:43 pmTYS - RSW
1 stop5h 02mDelta
Deal found 6/10$249
This American Airlines deal was found by Cheapflights users on 6/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/114:07 pmRSW - TYS
1 stop6h 07mAmerican Airlines
Fri 7/185:58 pmTYS - RSW
1 stop5h 32mAmerican Airlines
Deal found 6/11$254
This United Airlines deal was found by Cheapflights users on 6/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 6/271:45 pmRSW - TYS
2 stops10h 14mUnited Airlines
Tue 7/15:45 amTYS - RSW
1 stop5h 13mUnited Airlines
Deal found 6/12$264
This Mytrip deal was found by Cheapflights users on 6/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 7/139:34 pmRSW - TYS
1 stop19h 46mMultiple Airlines
Sun 7/208:54 pmTYS - RSW
2 stops23h 35mMultiple Airlines
Deal found 6/10$316

Cheapflights Fare Finder

Customize your flight search to find flights from Fort Myers to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
Use the filters below to find and compare flights from Fort Myers to Knoxville that are best for you.

Fly from

Fort Myers

Fly to

Knoxville

Route

Depart

Return

Price

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Fri 7/11

5:45 pm-11:59 pm

1 stop6h 14m

Knoxville McGhee Tyson

Thu 7/24

7:43 pm-12:45 am

1 stop5h 02m

$249

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Fri 7/11

4:07 pm-10:14 pm

1 stop6h 07m

Knoxville McGhee Tyson

Fri 7/18

5:58 pm-11:30 pm

1 stop5h 32m

$254

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Fri 6/27

1:45 pm-11:59 pm

2 stops10h 14m

Knoxville McGhee Tyson

Tue 7/1

5:45 am-10:58 am

1 stop5h 13m

$264

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Sun 7/13

9:34 pm-5:20 pm

1 stop19h 46m

Knoxville McGhee Tyson

Sun 7/20

8:54 pm-8:29 pm

2 stops23h 35m

$316

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Thu 6/19

8:09 pm-4:11 pm

2 stops20h 02m

$182

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Tue 8/26

11:57 am-10:01 pm

1 stop10h 04m

$214

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Tue 8/26

3:30 pm-11:57 pm

2 stops8h 27m

$244

Fort MyersKnoxville

RSW - TYS

RSWTYS

Fort Myers SW Florida Intl

Sun 6/15

5:40 am-11:08 am

1 stop5h 28m

$264

Flights are sorted by cheapest round-trip flights first.

Deals found on 6/11

Best time to book a flight from Fort Myers to Knoxville

Have a flexible travel schedule? Discover the best time to fly to Knoxville from Fort Myers with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Fort Myers to Knoxville

How far ahead should I book a flight from Fort Myers to Knoxville?

Use this chart to determine the optimal time to book a round-trip flight from Fort Myers to Knoxville. Price data was last updated on June 9, 2025.

To ensure you get the cheapest price possible for a flight from Fort Myers to Knoxville, you should look to book at least 50 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.

What is the cheapest month to book a flight from Fort Myers to Knoxville?

Currently, January is the cheapest month in which you can book a flight from Fort Myers to Knoxville (average of $296). Flying from Fort Myers to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

What is the cheapest time of day to fly from RSW to TYS?

Find hourly flight availability from Fort Myers to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated June 12, 2025.

When flying from Fort Myers to Knoxville, the time of day you fly usually plays a role in the price. Save by searching for a flight in the evening, which can drop the price by up to 40% versus a flight at noon.

What is the cheapest day to fly from Fort Myers to Knoxville?

Use this chart to determine the cheapest time to fly round-trip from Fort Myers to Knoxville. Price data was last updated on December 16, 2024.

Travelers seeking maximum savings on their Fort Myers to Knoxville flight should consider departing on Wednesday evenings when fares are most often at their lowest. Thursday at noon flights should be avoided if possible as fares are typically the most expensive at this time.

Rainfall in Knoxville by month

Plan your trip to Knoxville by taking into account the average rainfall totals by month.

In terms of precipitation, rainfall in Knoxville ranges from 2.7 - 4.8 inches per month. March is typically the wettest month, when rainfall can reach 4.8 in. October is typically the driest time to visit Knoxville when rainfall is around 2.7 in.

Temperature in Knoxville by month

Plan your trip to Knoxville by taking into account the average temperature totals by month.

If weather is an important factor for your trip to Knoxville, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 78.8 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 39.2 F).

Reviews of airlines servicing Knoxville

Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated June 12, 2025.
Read reviews from past customers who have flown Delta, United Airlines and American Airlines from Fort Myers to Knoxville. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
Delta
8.0
Very good
7,950 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
United Airlines
7.4
Good
8,790 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.
American Airlines
7.2
Good
10,000 reviews
Delta
8.0
Very good
7,950 reviews

Food

7.3

Boarding

8.2

Entertainment

7.9

Overall

8.0

Comfort

7.9

Crew

8.5

Reviews

1 / 20
6.0
Good

pilar,May 2025

RSW - ATL

The stewardess was not very nice because I requested two glasses of water. She didn’t even offer the snacks to me. She seemed angry and I felt very bad about her reaction. Also, the flight was full and you could not move. The airline should provide seats for obese people in consideration to the rest pf the passengers.

Related info for your journey

Find useful and relevant information for your journey from Fort Myers to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What are the cheapest airlines flying from Fort Myers to Knoxville round-trip?

    Delta, at $249, was found to be the cheapest airline from Fort Myers to Knoxville.Alternate airlines to your destination round-trip include American Airlines and United Airlines. Delta is priced at 21% lower than the current average price of a flight leaving 3 months from now.

  • What are the cheapest airlines to fly from Fort Myers to Knoxville one-way?

    For one-way options, check prices for American Airlines. According to our data, you can fly for as low as $214. Users have also found prices from $244 and $264 on United Airlines and Delta, respectively.

  • Can I find deals for flights from Fort Myers to Knoxville that include hotel bookings?

    Yes. In addition to deals on Fort Myers to Knoxville flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Fort Myers to Knoxville?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Fort Myers to Knoxville.

  • Can I find deals for business class flights from Fort Myers to Knoxville?

    Yes. Cheapflights offers flight deals from Fort Myers to Knoxville by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

  • What is the cheapest month to book a flight from Fort Myers to Knoxville?

    Currently, January is the cheapest month in which you can book a flight from Fort Myers to Knoxville (average of $296). Flying from Fort Myers to Knoxville in March is currently the most expensive (average of $376). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.

See more FAQs

Traveling to a place near Fort Myers?

Book flights to Fort Myers if you plan to visit one of these locations
Morristown
Cherokee
Corbin
Maryville
Oak Ridge
Alcoa
Murphy

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Top 2 airlines flying from Fort Myers to Knoxville

Discover the top 2 airlines that operate flights from Fort Myers to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated June 12, 2025.
AirlineCheapestAverageFlexibilityOn-time
American AirlinesCheapest$223Average$320FlexibilityNo cancel feeOn-time71%
DeltaCheapest$233Average$309FlexibilityNo cancel feeOn-timeN/A

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