$37+ Cheap flights from Florida Keys to Knoxville (TYS)
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 4/17. Fares are subject to change and may not be available on all flights or dates of travel.
EYW — TYS
May 2 — May 91
Round-trip
1 adult, Economy
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Find cheap flights from Florida Keys to Knoxville with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
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Cheapest flights from Florida Keys to KnoxvilleExplore the most affordable flight options available from Florida Keys to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
Explore the most affordable flight options available from Florida Keys to Knoxville. Find the lowest fares from popular airlines and budget airlines, with prices last updated on April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Mon 4/208:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$69
This Gotogate deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 4/178:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 3/3011:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 4/108:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$155
This Frontier deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
MIA
- TYS
1 stop13h 33m
Frontier
Mon 6/18:32 pm
TYS
- MIA
1 stop9h 01m
Frontier
Deal found 3/28![Frontier logo]()
$201
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:25 am
MIA
- TYS
1 stop10h 16m
Multiple Airlines
Sun 4/2611:27 am
TYS
- MIA
2 stops13h 22m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$202
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Multiple Airlines
Mon 4/201:15 pm
TYS
- EYW
3 stops23h 06m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:05 am
MIA
- TYS
2 stops15h 45m
Multiple Airlines
Sun 5/1011:27 am
TYS
- MIA
1 stop10h 45m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$212
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Mon 4/134:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Deal found 4/1![Frontier logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:01 am
EYW
- TYS
1 stop11h 32m
Multiple Airlines
Sun 4/124:31 pm
TYS
- EYW
1 stop16h 38m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:46 am
EYW
- TYS
1 stop8h 13m
Multiple Airlines
Mon 4/68:00 am
TYS
- EYW
Nonstop2h 11m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$232
This Priceline deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Mon 4/64:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Deal found 3/29![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:00 am
MIA
- TYS
1 stop12h 48m
Multiple Airlines
Sun 6/214:05 pm
TYS
- MIA
1 stop28h 28m
Multiple Airlines
Deal found 3/29![Multiple Airlines logo]()
$265
Best flights from Florida Keys to KnoxvilleDiscover carefully curated flight deals from Florida Keys to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
Discover carefully curated flight deals from Florida Keys to Knoxville that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated April 2, 2026.
This Gotogate deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 4/178:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Multiple Airlines
Mon 4/207:30 am
TYS
- EYW
2 stops28h 51m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$208
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:10 pm
MIA
- TYS
2 stops8h 40m
Southwest
Tue 5/58:15 am
TYS
- MIA
2 stops12h 25m
Southwest
Deal found 3/31![Southwest logo]()
$305
This Delta deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/36:18 pm
EYW
- TYS
1 stop5h 34m
Delta
Tue 8/115:30 am
TYS
- EYW
1 stop5h 28m
Delta
Deal found 3/28![Delta logo]()
$326
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:40 pm
EYW
- TYS
1 stop4h 19m
American Airlines
Tue 8/119:35 am
TYS
- EYW
2 stops9h 04m
American Airlines
Deal found 3/28![American Airlines logo]()
$384
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/86:40 am
MIA
- TYS
2 stops11h 30m
Southwest
Tue 5/128:15 am
TYS
- MIA
1 stop6h 00m
Southwest
Deal found 3/31![Southwest logo]()
$337
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/157:33 am
EYW
- TYS
1 stop6h 47m
Delta
Sun 4/195:40 am
TYS
- EYW
1 stop5h 06m
Delta
Deal found 3/31![Delta logo]()
$339
This United Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/164:38 pm
EYW
- TYS
2 stops29h 56m
United Airlines
Sun 4/197:00 am
TYS
- EYW
2 stops30h 31m
United Airlines
Deal found 3/30![United Airlines logo]()
$777
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/29:30 am
MIA
- TYS
1 stop9h 00m
Southwest
Mon 5/46:35 am
TYS
- MIA
2 stops10h 15m
Southwest
Deal found 3/30![Southwest logo]()
$355
This American Airlines deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/256:54 am
MIA
- TYS
1 stop7h 30m
American Airlines
Wed 4/297:00 am
TYS
- MIA
1 stop6h 12m
American Airlines
Deal found 3/28![American Airlines logo]()
$399
This American Airlines deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/119:45 pm
MIA
- TYS
Nonstop2h 14m
American Airlines
Mon 6/156:00 am
TYS
- MIA
Nonstop2h 13m
American Airlines
Deal found 4/1![American Airlines logo]()
$403
This Southwest deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/276:40 am
MIA
- TYS
2 stops11h 30m
Southwest
Thu 4/308:05 am
TYS
- MIA
1 stop6h 25m
Southwest
Deal found 3/30![Southwest logo]()
$389
This American Airlines deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/174:20 pm
EYW
- TYS
1 stop7h 35m
American Airlines
Mon 4/205:57 pm
TYS
- EYW
1 stop4h 39m
American Airlines
Deal found 3/30![American Airlines logo]()
$453
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 5/177:00 am
MIA
- TYS
2 stops14h 05m
Southwest
Thu 5/2112:15 pm
TYS
- MIA
2 stops10h 45m
Southwest
Deal found 4/1![Southwest logo]()
$423
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/116:35 am
MIA
- TYS
1 stop6h 45m
Southwest
Tue 4/147:05 am
TYS
- MIA
1 stop5h 35m
Southwest
Deal found 3/28![Southwest logo]()
$432
Last-minute flights from Florida Keys to KnoxvilleDiscover last-minute flight deals from Florida Keys to Knoxville. Data last updated April 2, 2026 and is based on user searches.
Discover last-minute flight deals from Florida Keys to Knoxville. Data last updated April 2, 2026 and is based on user searches.
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/29:46 am
EYW
- TYS
1 stop8h 13m
Multiple Airlines
Mon 4/68:00 am
TYS
- EYW
Nonstop2h 11m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$232
This Priceline deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/35:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Mon 4/64:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Deal found 3/29![Frontier logo]()
$240
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/911:01 am
EYW
- TYS
1 stop11h 32m
Multiple Airlines
Sun 4/124:31 pm
TYS
- EYW
1 stop16h 38m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$227
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/105:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Mon 4/134:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
Deal found 4/1![Frontier logo]()
$222
This Gotogate deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Gotogate is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 4/1311:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Fri 4/178:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$129
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/1511:51 am
EYW
- TYS
2 stops27h 50m
Multiple Airlines
Sun 4/191:14 pm
TYS
- EYW
1 stop25h 29m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Mon 4/208:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$69
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Multiple Airlines
Mon 4/201:15 pm
TYS
- EYW
3 stops23h 06m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$205
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/235:25 am
MIA
- TYS
1 stop10h 16m
Multiple Airlines
Sun 4/2611:27 am
TYS
- MIA
2 stops13h 22m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$202
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/2812:35 pm
MIA
- TYS
1 stop8h 15m
Southwest
Tue 5/58:15 am
TYS
- MIA
1 stop6h 00m
Southwest
Deal found 3/31![Southwest logo]()
$295
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/75:05 am
MIA
- TYS
2 stops15h 45m
Multiple Airlines
Sun 5/1011:27 am
TYS
- MIA
1 stop10h 45m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$212
This Frontier deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
MIA
- TYS
1 stop13h 33m
Frontier
Mon 6/18:32 pm
TYS
- MIA
1 stop9h 01m
Frontier
Deal found 3/28![Frontier logo]()
$201
One-way flights from Florida Keys to KnoxvilleSearch for one-way flight options from Florida Keys to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
Search for one-way flight options from Florida Keys to Knoxville. Find affordable one-way fares based on user searches. Data last updated April 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$37
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/309:38 pm
MIA
- TYS
1 stop22h 51m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$88
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 5/276:00 am
MIA
- TYS
1 stop13h 33m
Frontier
Deal found 3/31![Frontier logo]()
$96
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/93:08 pm
EYW
- TYS
1 stop7h 25m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$106
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 6/188:00 am
MIA
- TYS
1 stop12h 48m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$108
This Priceline deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 4/307:00 am
MIA
- TYS
1 stop8h 33m
Frontier
Deal found 3/31![Frontier logo]()
$111
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 4/287:04 pm
MIA
- TYS
2 stops15h 32m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$112
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 6/289:16 pm
EYW
- TYS
1 stop23h 57m
Allegiant Air
Deal found 4/1![Allegiant Air logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 4/255:05 am
MIA
- TYS
2 stops34h 36m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$113
This Frontier deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/296:00 am
MIA
- TYS
1 stop13h 33m
Frontier
Deal found 3/31![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 4/291:10 pm
MIA
- TYS
2 stops26h 31m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/28:00 am
MIA
- TYS
1 stop12h 21m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$123
Find flight deals from Florida Keys to Knoxville
Keep the following information in mind while searching for Florida Keys to Knoxville flight deals. Data was last updated April 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $69 (Kiwi.com) |
One-way from | $37 (Kiwi.com) |
Popular in | September |
Cheapest in | March |
Average price | $248 |
Cheapflights Fare Finder
Customize your flight search to find flights from Florida Keys to Knoxville that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
Use the filters below to find and compare flights from Florida Keys to Knoxville that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
Quickest round-trip
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 4/13
11:01 am-1:16 pm
Nonstop2h 15m
Knoxville McGhee Tyson
Fri 4/17
8:00 am-10:11 am
Nonstop2h 11m
$129
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Fri 4/17
11:01 am-1:16 pm
Nonstop2h 15m
Knoxville McGhee Tyson
Mon 4/20
7:30 am-12:21 pm
2 stops28h 51m
$208
MiamiKnoxville
MIA - TYS
MIATYS
Miami
Tue 4/28
12:10 pm-8:50 pm
2 stops8h 40m
Knoxville McGhee Tyson
Tue 5/5
8:15 am-8:40 pm
2 stops12h 25m
$305
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 8/3
6:18 pm-11:52 pm
1 stop5h 34m
Knoxville McGhee Tyson
Tue 8/11
5:30 am-10:58 am
1 stop5h 28m
$326
MiamiKnoxville
MIA - TYS
MIATYS
Miami
Fri 5/8
6:40 am-6:10 pm
2 stops11h 30m
Knoxville McGhee Tyson
Tue 5/12
8:15 am-2:15 pm
1 stop6h 00m
$337
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Wed 4/15
7:33 am-2:20 pm
1 stop6h 47m
Knoxville McGhee Tyson
Sun 4/19
5:40 am-10:46 am
1 stop5h 06m
$339
MiamiKnoxville
MIA - TYS
MIATYS
Miami
Sat 5/2
9:30 am-6:30 pm
1 stop9h 00m
Knoxville McGhee Tyson
Mon 5/4
6:35 am-4:50 pm
2 stops10h 15m
$355
Key WestKnoxville
EYW - TYS
EYWTYS
Key West
Mon 8/3
7:40 pm-11:59 pm
1 stop4h 19m
Knoxville McGhee Tyson
Tue 8/11
9:35 am-6:39 pm
2 stops9h 04m
$384
MiamiKnoxville
MIA - TYS
MIATYS
Miami
Mon 4/27
6:40 am-6:10 pm
2 stops11h 30m
Knoxville McGhee Tyson
Thu 4/30
8:05 am-2:30 pm
1 stop6h 25m
$389
MiamiKnoxville
MIA - TYS
MIATYS
Miami
Sat 4/25
6:54 am-2:24 pm
1 stop7h 30m
Knoxville McGhee Tyson
Wed 4/29
7:00 am-1:12 pm
1 stop6h 12m
$399
Showing 1-10 of 35 resultsSorted by cheapest first
Best time to book a flight from Florida Keys to Knoxville
Have a flexible travel schedule? Discover the best time to fly to Knoxville from Florida Keys with our price prediction graph.
EYW-TYS
MIA-TYS
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Florida Keys to Knoxville
zzEOA-TYS
EYW-TYS
MIA-TYS
What is the cheapest time of day to fly from EOA to TYS?
Find hourly flight availability from Florida Keys to Knoxville. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated April 2, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Florida Keys to Knoxville as you normally would.
Reviews of airlines servicing Knoxville
Get insights into the airlines that provide service to Knoxville. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Knoxville. Reviews last updated April 2, 2026.
See what other customers who have flown with Delta,Allegiant Air, andAmerican Airlines from Florida Keys to Knoxville have to say. Users have also rated airlines in terms of entertainment options, comfort, food, crew/service, and boarding process.
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Overall
7.9
Boarding
8.1
Crew
8.5
Entertainment
7.8
Comfort
7.9
Food
7.2
Reviews
1 / 20
6.0
Goodpilar,May 2025
RSW - ATL
Related info for your journey
Find useful and relevant information for your journey from Florida Keys to Knoxville. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Traveling to a place near Knoxville?
Book flights to Knoxville if you plan to visit one of these locationsCherokee
Crossville
Corbin
Morristown
Bryson City
Alcoa
Murphy
Oak Ridge
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Other flights to Knoxville
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Florida Keys and Knoxville flights
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Consider these flights traveling from Florida Keys to Knoxville.
Top 2 airlines flying from Florida Keys to Knoxville
Discover the top 2 airlines that operate flights from Florida Keys to Knoxville. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated April 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$248 | Average$485 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$273 | Average$498 | FlexibilityNo cancel fee | On-timeN/A |