$63+ Cheap flights from Knoxville (TYS) to Florida Keys
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 8/3. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
Aug 9 — Aug 161
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Knoxville to Florida Keys with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Knoxville to Florida Keys
Cheapest
Best
Last-minute
One-way
Cheapest flights from Knoxville to Florida KeysExplore the most affordable flight options available from Knoxville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
Explore the most affordable flight options available from Knoxville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 10, 2026.
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 8/710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$63
This Trip.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/1710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$83
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 8/1410:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$87
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$95
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/1010:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$97
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 7/1710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$110
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/36:06 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Wed 9/98:54 pm
MIA
- TYS
Nonstop2h 13m
American Airlines
Deal found 7/7![American Airlines logo]()
$193
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:26 pm
TYS
- MIA
1 stop26h 56m
Multiple Airlines
Mon 8/246:50 am
MIA
- TYS
1 stop11h 53m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$204
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/175:43 pm
TYS
- MIA
2 stops24h 39m
Multiple Airlines
Sat 10/242:23 pm
MIA
- TYS
1 stop19h 21m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$205
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:38 pm
TYS
- MIA
1 stop4h 56m
Delta
Fri 8/78:25 am
MIA
- TYS
1 stop5h 03m
Delta
Deal found 7/7![Delta logo]()
$211
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
TYS
- MIA
1 stop5h 00m
Delta
Tue 8/257:00 am
MIA
- TYS
1 stop6h 34m
Delta
Deal found 7/8![Delta logo]()
$213
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Fri 8/79:42 pm
MIA
- TYS
Nonstop2h 09m
American Airlines
Deal found 7/7![American Airlines logo]()
$220
Best flights from Knoxville to Florida KeysDiscover carefully curated flight deals from Knoxville to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
Discover carefully curated flight deals from Knoxville to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated July 10, 2026.
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/173:27 pm
EYW
- TYS
1 stop4h 51m
Allegiant Air
Deal found 7/5![Allegiant Air logo]()
$136
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/318:25 am
TYS
- MIA
1 stop8h 00m
Southwest
Wed 9/211:50 am
MIA
- TYS
1 stop8h 00m
Southwest
Deal found 7/7![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:30 am
TYS
- EYW
Nonstop2h 11m
Multiple Airlines
Fri 7/3112:07 pm
EYW
- TYS
3 stops20h 25m
Multiple Airlines
Deal found 7/8![Multiple Airlines logo]()
$287
This Delta deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/410:28 am
TYS
- EYW
1 stop6h 52m
Delta
Tue 8/116:15 pm
EYW
- TYS
1 stop5h 37m
Delta
Deal found 7/5![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:06 am
TYS
- EYW
1 stop5h 02m
American Airlines
Sat 9/57:10 pm
EYW
- TYS
1 stop4h 41m
American Airlines
Deal found 7/5![American Airlines logo]()
$309
This Mytrip deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/317:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/310:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$162
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/16:42 pm
TYS
- EYW
1 stop20h 00m
Allegiant Air
Fri 8/73:27 pm
EYW
- TYS
1 stop4h 51m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$203
This Southwest deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Tue 9/87:10 am
MIA
- TYS
1 stop5h 55m
Southwest
Deal found 7/9![Southwest logo]()
$234
This Southwest deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/268:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Mon 8/317:00 am
MIA
- TYS
1 stop10h 10m
Southwest
Deal found 7/8![Southwest logo]()
$240
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Wed 8/127:10 am
MIA
- TYS
1 stop5h 55m
Southwest
Deal found 7/10![Southwest logo]()
$246
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2011:35 am
TYS
- EYW
1 stop4h 44m
Allegiant Air
Sun 8/233:51 pm
EYW
- TYS
1 stop25h 46m
Allegiant Air
Deal found 7/9![Allegiant Air logo]()
$255
This Delta deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/295:40 am
TYS
- EYW
1 stop5h 20m
Delta
Wed 8/56:15 pm
EYW
- TYS
1 stop5h 39m
Delta
Deal found 7/9![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/1812:23 pm
TYS
- EYW
1 stop5h 01m
Delta
Mon 9/216:19 pm
EYW
- TYS
1 stop5h 36m
Delta
Deal found 7/6![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am
TYS
- EYW
1 stop4h 47m
Delta
Tue 9/156:19 pm
EYW
- TYS
1 stop5h 36m
Delta
Deal found 7/7![Delta logo]()
$309
This Southwest deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/218:25 am
TYS
- MIA
2 stops12h 20m
Southwest
Mon 8/247:00 am
MIA
- TYS
2 stops11h 35m
Southwest
Deal found 7/10![Southwest logo]()
$287
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/86:00 pm
TYS
- EYW
1 stop19h 31m
Allegiant Air
Sat 8/154:35 pm
EYW
- TYS
1 stop19h 56m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$288
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:40 pm
TYS
- MIA
1 stop9h 25m
Southwest
Mon 8/107:00 am
MIA
- TYS
2 stops11h 35m
Southwest
Deal found 7/6![Southwest logo]()
$312
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/88:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Wed 9/167:30 am
MIA
- TYS
2 stops11h 25m
Southwest
Deal found 7/6![Southwest logo]()
$362
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/198:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Sun 8/236:45 am
MIA
- TYS
1 stop8h 15m
Southwest
Deal found 7/6![Southwest logo]()
$362
Last-minute flights from Knoxville to Florida KeysDiscover last-minute flight deals from Knoxville to Florida Keys. Data last updated July 10, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Florida Keys. Data last updated July 10, 2026 and is based on user searches.
This Super.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/137:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 7/1710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$110
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 7/277:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 7/3110:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$95
This Super.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 8/710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$63
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/37:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/1010:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$97
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/54:38 pm
TYS
- MIA
1 stop4h 56m
Delta
Fri 8/78:25 am
MIA
- TYS
1 stop5h 03m
Delta
Deal found 7/7![Delta logo]()
$211
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/56:00 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Fri 8/79:42 pm
MIA
- TYS
Nonstop2h 09m
American Airlines
Deal found 7/7![American Airlines logo]()
$220
This Southwest deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 8/58:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Wed 8/127:10 am
MIA
- TYS
1 stop5h 55m
Southwest
Deal found 7/6![Southwest logo]()
$234
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/77:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Fri 8/1410:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$87
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/133:56 pm
TYS
- MIA
2 stops21h 57m
Multiple Airlines
Mon 8/176:30 am
MIA
- TYS
1 stop16h 42m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$228
This Trip.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Trip.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/147:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Mon 8/1710:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 7/7![Allegiant Air logo]()
$83
This Delta deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/156:00 am
TYS
- MIA
1 stop5h 00m
Delta
Tue 8/257:00 am
MIA
- TYS
1 stop6h 34m
Delta
Deal found 7/8![Delta logo]()
$213
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/211:26 pm
TYS
- MIA
1 stop26h 56m
Multiple Airlines
Mon 8/246:50 am
MIA
- TYS
1 stop11h 53m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$204
One-way flights from Knoxville to Florida KeysSearch for one-way flight options from Knoxville to Florida Keys. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
Search for one-way flight options from Knoxville to Florida Keys. Find affordable one-way fares based on user searches. Data last updated July 10, 2026.
This American Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:06 am
TYS
- MIA
Nonstop2h 12m
American Airlines
Deal found 7/7![American Airlines logo]()
$97
This Kiwi.com deal was found by Cheapflights users on 7/8. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/223:57 pm
TYS
- EYW
1 stop17h 13m
Allegiant Air
Deal found 7/8![Allegiant Air logo]()
$103
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/107:30 am
TYS
- MIA
1 stop5h 32m
Delta
Deal found 7/7![Delta logo]()
$106
This Delta deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/45:40 am
TYS
- MIA
1 stop5h 20m
Delta
Deal found 7/7![Delta logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/312:53 pm
TYS
- MIA
1 stop9h 26m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$108
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/175:54 pm
TYS
- MIA
1 stop20h 39m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$109
This Kiwi.com deal was found by Cheapflights users on 7/6. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/66:09 pm
TYS
- EYW
1 stop21h 33m
Allegiant Air
Deal found 7/6![Allegiant Air logo]()
$110
This Kiwi.com deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/15:59 pm
TYS
- EYW
1 stop19h 23m
Allegiant Air
Deal found 7/5![Allegiant Air logo]()
$111
This Southwest deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/228:05 am
TYS
- MIA
1 stop5h 30m
Southwest
Deal found 7/7![Southwest logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 7/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:54 pm
TYS
- MIA
2 stops31h 10m
Multiple Airlines
Deal found 7/10![Multiple Airlines logo]()
$118
This Kiwi.com deal was found by Cheapflights users on 7/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 8/106:29 pm
TYS
- MIA
2 stops23h 18m
Multiple Airlines
Deal found 7/9![Multiple Airlines logo]()
$120
This Kiwi.com deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/712:50 pm
TYS
- MIA
2 stops31h 39m
Multiple Airlines
Deal found 7/7![Multiple Airlines logo]()
$121
Find flight deals from Knoxville to Florida Keys
Keep the following information in mind while searching for Knoxville to Florida Keys flight deals. Data was last updated July 10, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $63 (Super.com) |
Popular in | March |
Cheapest in | August |
Average price | $407 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
Use the filters below to find and compare flights from Knoxville to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
Fri 8/14
7:30 am-9:41 am
Nonstop2h 11m
Key West
Mon 8/17
3:27 pm-8:18 pm
1 stop4h 51m
$136
Quickest round-trip
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
Fri 7/31
7:30 am-9:41 am
Nonstop2h 11m
Key West
Mon 8/3
10:31 am-12:46 pm
Nonstop2h 15m
$162
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
Sat 8/1
6:42 pm-2:42 pm
1 stop20h 00m
Key West
Fri 8/7
3:27 pm-8:18 pm
1 stop4h 51m
$203
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Mon 8/31
8:25 am-4:25 pm
1 stop8h 00m
Miami
Wed 9/2
11:50 am-7:50 pm
1 stop8h 00m
$234
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Tue 9/1
8:05 am-1:35 pm
1 stop5h 30m
Miami
Tue 9/8
7:10 am-1:05 pm
1 stop5h 55m
$234
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Wed 8/26
8:05 am-1:35 pm
1 stop5h 30m
Miami
Mon 8/31
7:00 am-5:10 pm
1 stop10h 10m
$240
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Wed 8/5
8:05 am-1:35 pm
1 stop5h 30m
Miami
Wed 8/12
7:10 am-1:05 pm
1 stop5h 55m
$246
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
Thu 8/20
11:35 am-4:19 pm
1 stop4h 44m
Key West
Sun 8/23
3:51 pm-5:37 pm
1 stop25h 46m
$255
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
Mon 7/27
7:30 am-9:41 am
Nonstop2h 11m
Key West
Fri 7/31
12:07 pm-8:32 am
3 stops20h 25m
$287
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
Fri 8/21
8:25 am-8:45 pm
2 stops12h 20m
Miami
Mon 8/24
7:00 am-6:35 pm
2 stops11h 35m
$287
Showing 1-10 of 36 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Knoxville with our price prediction graph.
TYS-EYW
TYS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Florida Keys
TYS-zzEOA
TYS-EYW
TYS-MIA
What is the cheapest month to book a flight from Knoxville to Florida Keys?
Currently, January is the cheapest month in which you can book a flight from Knoxville to Florida Keys (average of $46). Flying from Knoxville to Florida Keys in April is currently the most expensive (average of $116). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to EOA?
Find hourly flight availability from Knoxville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated July 10, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Florida Keys as you normally would.
How far ahead should I book a flight from Knoxville to Florida Keys?
To ensure you get the cheapest price possible for a flight from Knoxville to Florida Keys, you should look to book at least 67 days in advance of your intended travel date. The price of your flight may increase if you delay and leave booking until a week or so before departure.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated July 10, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAllegiant Air from Knoxville to Florida Keys by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Crew
8.6
Comfort
8.0
Boarding
8.1
Overall
7.9
Entertainment
7.5
Food
7.0
Reviews
1 / 20
6.0
GoodScott,Feb 2026
HOU - FLL
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Popular flights
Alternative routes for Knoxville to Florida Keys
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Florida Keys by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Knoxville to Florida Keys by cabin class
Find flights from Knoxville to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Florida Keys flights
Browse other Knoxville and Florida Keys flight options. Last updated on July 10, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Knoxville to Florida Keys
Discover the top 3 airlines that operate flights from Knoxville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 10, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$82 | Average$145 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$250 | Average$442 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$283 | Average$418 | FlexibilityNo cancel fee | On-timeN/A |