$32+ Cheap flights from Knoxville (TYS) to Florida Keys
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 5/11. Fares are subject to change and may not be available on all flights or dates of travel.
TYS — EYW
maj 2 — maj 91
Round-trip
1 adult, Economy
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Cheapest flights from Knoxville to Florida KeysExplore the most affordable flight options available from Knoxville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Kwiecień 2, 2026.
Explore the most affordable flight options available from Knoxville to Florida Keys. Find the lowest fares from popular airlines and budget airlines, with prices last updated on Kwiecień 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/138:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pt. 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/31![Allegiant Air logo]()
$65
This Super.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/208:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pt. 4/2411:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$72
This Super.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/138:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 5/1111:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$77
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/88:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 5/1111:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/248:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 4/2711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$82
This Super.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/178:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 4/2011:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$94
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 6/267:30 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 7/610:31 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$128
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/2912:55 pm
TYS
- MIA
1 stop9h 17m
Multiple Airlines
pt. 6/59:15 am
MIA
- TYS
1 stop13h 25m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$207
This Priceline deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 4/304:28 pm
TYS
- MIA
1 stop12h 37m
Frontier
ndz. 5/37:00 am
MIA
- TYS
1 stop8h 33m
Frontier
Deal found 3/30![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 6/112:55 pm
TYS
- MIA
1 stop9h 17m
Multiple Airlines
pt. 6/54:03 pm
MIA
- TYS
1 stop19h 46m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$235
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/64:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
pt. 4/105:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Deal found 4/1![Frontier logo]()
$236
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 6/73:46 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
ndz. 6/148:10 am
MIA
- TYS
2 stops37h 03m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$241
Best flights from Knoxville to Florida KeysDiscover carefully curated flight deals from Knoxville to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Kwiecień 2, 2026.
Discover carefully curated flight deals from Knoxville to Florida Keys that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated Kwiecień 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 4/124:31 pm
TYS
- EYW
1 stop22h 12m
Allegiant Air
czw. 4/163:08 pm
EYW
- TYS
1 stop7h 25m
Allegiant Air
Deal found 3/28![Allegiant Air logo]()
$210
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/257:30 am
TYS
- EYW
Nonstop2h 11m
Multiple Airlines
sob. 5/302:48 pm
EYW
- TYS
3 stops29h 41m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$271
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 4/308:05 am
TYS
- MIA
1 stop6h 25m
Southwest
ndz. 5/37:00 am
MIA
- TYS
1 stop7h 05m
Southwest
Deal found 4/1![Southwest logo]()
$334
This Delta deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 6/243:54 pm
TYS
- EYW
1 stop3h 59m
Delta
pon. 6/291:18 pm
EYW
- TYS
1 stop3h 57m
Delta
Deal found 4/2![Delta logo]()
$334
This American Airlines deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/83:58 pm
TYS
- EYW
1 stop6h 38m
American Airlines
pon. 5/113:58 pm
EYW
- TYS
2 stops7h 57m
American Airlines
Deal found 4/2![American Airlines logo]()
$386
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/245:39 pm
TYS
- EYW
1 stop17h 25m
Allegiant Air
pon. 4/273:33 pm
EYW
- TYS
1 stop6h 15m
Allegiant Air
Deal found 4/1![Allegiant Air logo]()
$249
This Southwest deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 4/227:05 am
TYS
- MIA
1 stop5h 35m
Southwest
pt. 4/2412:05 pm
MIA
- TYS
2 stops8h 15m
Southwest
Deal found 3/31![Southwest logo]()
$371
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 4/154:25 pm
TYS
- EYW
1 stop19h 06m
Multiple Airlines
ndz. 4/199:58 am
EYW
- TYS
2 stops26h 55m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$387
This Delta deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 4/155:40 am
TYS
- EYW
1 stop5h 06m
Delta
pon. 4/207:33 am
EYW
- TYS
1 stop6h 47m
Delta
Deal found 3/30![Delta logo]()
$393
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/316:40 am
TYS
- MIA
2 stops9h 25m
Southwest
pon. 6/85:40 am
MIA
- TYS
2 stops15h 30m
Southwest
Deal found 4/1![Southwest logo]()
$390
This Southwest deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/247:30 am
TYS
- MIA
2 stops9h 05m
Southwest
pt. 5/291:45 pm
MIA
- TYS
2 stops7h 30m
Southwest
Deal found 3/29![Southwest logo]()
$407
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/151:59 pm
TYS
- EYW
1 stop5h 50m
Delta
pon. 5/186:19 pm
EYW
- TYS
1 stop5h 37m
Delta
Deal found 3/29![Delta logo]()
$492
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
sob. 6/138:00 am
TYS
- MIA
2 stops14h 05m
Southwest
sob. 6/207:15 am
MIA
- TYS
2 stops12h 20m
Southwest
Deal found 3/28![Southwest logo]()
$425
This American Airlines deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/185:00 am
TYS
- EYW
1 stop6h 16m
American Airlines
pon. 5/184:20 pm
EYW
- TYS
1 stop7h 35m
American Airlines
Deal found 3/29![American Airlines logo]()
$619
This Delta deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/1711:56 am
TYS
- MIA
1 stop4h 52m
Delta
sob. 5/237:39 pm
MIA
- TYS
1 stop4h 22m
Delta
Deal found 3/29![Delta logo]()
$551
This Southwest deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 6/127:30 am
TYS
- MIA
1 stop6h 40m
Southwest
pon. 6/155:35 am
MIA
- TYS
1 stop8h 10m
Southwest
Deal found 3/28![Southwest logo]()
$462
This Southwest deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Southwest is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/66:30 am
TYS
- MIA
1 stop6h 50m
Southwest
pon. 4/136:40 am
MIA
- TYS
2 stops11h 30m
Southwest
Deal found 4/1![Southwest logo]()
$526
This Delta deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 4/195:40 am
TYS
- EYW
1 stop5h 06m
Delta
ndz. 4/266:23 pm
EYW
- TYS
1 stop5h 31m
Delta
Deal found 3/31![Delta logo]()
$659
Last-minute flights from Knoxville to Florida KeysDiscover last-minute flight deals from Knoxville to Florida Keys. Data last updated Kwiecień 2, 2026 and is based on user searches.
Discover last-minute flight deals from Knoxville to Florida Keys. Data last updated Kwiecień 2, 2026 and is based on user searches.
This Frontier deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/64:20 pm
TYS
- MIA
1 stop13h 29m
Frontier
pt. 4/105:50 am
MIA
- TYS
1 stop9h 38m
Frontier
Deal found 4/1![Frontier logo]()
$236
This Mytrip deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Mytrip is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/108:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 4/1311:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/30![Allegiant Air logo]()
$134
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/138:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pt. 4/1711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/31![Allegiant Air logo]()
$65
This Super.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/138:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 5/1111:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$77
This Super.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/178:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 4/2011:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$94
This Super.com deal was found by Cheapflights users on 3/29. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Super.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/208:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pt. 4/2411:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 3/29![Allegiant Air logo]()
$72
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 4/218:00 am
TYS
- MIA
1 stop13h 29m
Multiple Airlines
czw. 4/235:05 am
MIA
- TYS
2 stops15h 37m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 4/248:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 4/2711:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$82
This Priceline deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Priceline is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 4/304:28 pm
TYS
- MIA
1 stop12h 37m
Frontier
ndz. 5/37:00 am
MIA
- TYS
1 stop8h 33m
Frontier
Deal found 3/30![Frontier logo]()
$225
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/88:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
pon. 5/1111:01 am
EYW
- TYS
Nonstop2h 15m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$78
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/243:46 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
pt. 5/296:00 am
MIA
- TYS
1 stop13h 33m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$263
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pt. 5/2912:55 pm
TYS
- MIA
1 stop9h 17m
Multiple Airlines
pt. 6/59:15 am
MIA
- TYS
1 stop13h 25m
Multiple Airlines
Deal found 4/1![Multiple Airlines logo]()
$207
One-way flights from Knoxville to Florida KeysSearch for one-way flight options from Knoxville to Florida Keys. Find affordable one-way fares based on user searches. Data last updated Kwiecień 2, 2026.
Search for one-way flight options from Knoxville to Florida Keys. Find affordable one-way fares based on user searches. Data last updated Kwiecień 2, 2026.
This Kiwi.com deal was found by Cheapflights users on 4/2. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 5/118:00 am
TYS
- EYW
Nonstop2h 11m
Allegiant Air
Deal found 4/2![Allegiant Air logo]()
$32
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 6/18:32 pm
TYS
- MIA
1 stop9h 01m
Frontier
Deal found 3/30![Frontier logo]()
$90
This Kiwi.com deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/243:46 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Deal found 3/28![Multiple Airlines logo]()
$99
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 5/283:46 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$105
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 5/313:46 pm
TYS
- MIA
1 stop28h 42m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$107
This Kiwi.com deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
ndz. 4/2611:27 am
TYS
- MIA
2 stops37h 22m
Multiple Airlines
Deal found 3/30![Multiple Airlines logo]()
$113
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 4/271:15 pm
TYS
- MIA
2 stops22h 48m
Multiple Airlines
Deal found 3/31![Multiple Airlines logo]()
$114
This Frontier deal was found by Cheapflights users on 3/30. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
pon. 6/298:32 pm
TYS
- MIA
1 stop9h 22m
Frontier
Deal found 3/30![Frontier logo]()
$115
This Frontier deal was found by Cheapflights users on 3/28. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Frontier is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
czw. 4/304:28 pm
TYS
- MIA
1 stop12h 37m
Frontier
Deal found 3/28![Frontier logo]()
$117
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
wt. 4/74:54 pm
TYS
- EYW
1 stop18h 55m
Allegiant Air
Deal found 3/31![Allegiant Air logo]()
$123
This Kiwi.com deal was found by Cheapflights users on 4/1. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 4/2911:26 am
TYS
- EYW
1 stop26h 53m
Allegiant Air
Deal found 4/1![Allegiant Air logo]()
$144
This Kiwi.com deal was found by Cheapflights users on 3/31. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
śr. 5/202:20 pm
TYS
- EYW
1 stop23h 04m
Allegiant Air
Deal found 3/31![Allegiant Air logo]()
$154
Find flight deals from Knoxville to Florida Keys
Keep the following information in mind while searching for Knoxville to Florida Keys flight deals. Data was last updated Kwiecień 2, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $65 (Kiwi.com) |
One-way from | $32 (Kiwi.com) |
Popular in | March |
Cheapest in | February |
Average price | $359 |
Cheapflights Fare Finder
Customize your flight search to find flights from Knoxville to Florida Keys that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Kwiecień 2, 2026.
Use the filters below to find and compare flights from Knoxville to Florida Keys that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
ndz. 4/12
4:31 pm-2:43 pm
1 stop22h 12m
Key West
czw. 4/16
3:08 pm-10:33 pm
1 stop7h 25m
$210
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
pt. 4/24
5:39 pm-11:04 am
1 stop17h 25m
Key West
pon. 4/27
3:33 pm-9:48 pm
1 stop6h 15m
$249
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
pon. 5/25
7:30 am-9:41 am
Nonstop2h 11m
Key West
sob. 5/30
2:48 pm-8:29 pm
3 stops29h 41m
$271
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
czw. 4/30
8:05 am-2:30 pm
1 stop6h 25m
Miami
ndz. 5/3
7:00 am-2:05 pm
1 stop7h 05m
$334
Quickest round-trip
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
śr. 6/24
3:54 pm-7:53 pm
1 stop3h 59m
Key West
pon. 6/29
1:18 pm-5:15 pm
1 stop3h 57m
$334
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
śr. 4/22
7:05 am-12:40 pm
1 stop5h 35m
Miami
pt. 4/24
12:05 pm-8:20 pm
2 stops8h 15m
$371
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
pt. 5/8
3:58 pm-10:36 pm
1 stop6h 38m
Key West
pon. 5/11
3:58 pm-11:55 pm
2 stops7h 57m
$386
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
śr. 4/15
4:25 pm-11:31 am
1 stop19h 06m
Key West
ndz. 4/19
9:58 am-12:53 pm
2 stops26h 55m
$387
KnoxvilleMiami
TYS - MIA
TYSMIA
Knoxville McGhee Tyson
ndz. 5/31
6:40 am-4:05 pm
2 stops9h 25m
Miami
pon. 6/8
5:40 am-9:10 pm
2 stops15h 30m
$390
KnoxvilleKey West
TYS - EYW
TYSEYW
Knoxville McGhee Tyson
śr. 4/15
5:40 am-10:46 am
1 stop5h 06m
Key West
pon. 4/20
7:33 am-2:20 pm
1 stop6h 47m
$393
Showing 1-10 of 37 resultsSorted by cheapest first
Best time to book a flight from Knoxville to Florida Keys
Have a flexible travel schedule? Discover the best time to fly to Florida Keys from Knoxville with our price prediction graph.
TYS-EYW
TYS-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Knoxville to Florida Keys
TYS-zzEOA
TYS-EYW
TYS-MIA
What is the cheapest month to book a flight from Knoxville to Florida Keys?
Currently, February is the cheapest month in which you can book a flight from Knoxville to Florida Keys (average of $84). Flying from Knoxville to Florida Keys in April is currently the most expensive (average of $93). There are several factors that can impact the price of a flight, so comparing airlines, departure airports and flight times can provide users with more options.
What is the cheapest time of day to fly from TYS to EOA?
Find hourly flight availability from Knoxville to Florida Keys. Discover flight options and departure times throughout the day, allowing you to choose a departure time that suits your schedule. Data last updated Kwiecień 2, 2026.
Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Knoxville to Florida Keys as you normally would.
Reviews of airlines servicing Florida Keys
Get insights into the airlines that provide service to Florida Keys. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Florida Keys. Reviews last updated Kwiecień 2, 2026.
Get a feel of what it's like to fly with Southwest,Delta, andAllegiant Air from Knoxville to Florida Keys by reading reviews from past customers. You can also see how each airline stacks up in terms of entertainment options, comfort, food, crew/service, and boarding process.
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Entertainment
7.5
Comfort
8.0
Crew
8.6
Food
7.0
Boarding
8.1
Overall
8.0
Reviews
1 / 20
2.0
MediocreDominic,Mar 2026
MCO - SMF
Related info for your journey
Find useful and relevant information for your journey from Knoxville to Florida Keys. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
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Complete your trip
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Find flights from Knoxville to Florida Keys, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Knoxville and Florida Keys flights
Browse other Knoxville and Florida Keys flight options. Last updated on Kwiecień 2, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Top 3 airlines flying from Knoxville to Florida Keys
Discover the top 3 airlines that operate flights from Knoxville to Florida Keys. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated Kwiecień 2, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$84 | Average$154 | FlexibilityNo cancel fee | On-time88% | |
| Cheapest$248 | Average$388 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$268 | Average$395 | FlexibilityNo cancel fee | On-timeN/A |