HomeSearch by dateVacation packagesHotelsFlight dealsCar rentalTravel tips & news
Kissimmee

$427+ Cheap flights from Florence, SC (FLO) to Kissimmee, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 9/7. Fares are subject to change and may not be available on all flights or dates of travel.
FLO — MCO
Aug 24 — Aug 311
Mon 8/24
Mon 8/31
1 adult, Economy
We work with more than 300 partners to bring you better travel deals

Find cheap flights from Florence to Kissimmee with Cheapflights

1. Tell us where you want to go

Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”

2. Select your favorite providers

We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.

3. Compare prices and book

Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.

Cheap flight deals from Florence to Kissimmee

Cheapest flights from Florence to Kissimmee
Explore the most affordable flight options available from Florence to Kissimmee. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 25, 2026.

This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/52:37 pm
FLO
-
MCO
1 stop5h 26m
American Airlines
Mon 9/75:36 pm
MCO
-
FLO
1 stop5h 23m
American Airlines
Deal found 7/22$491
This American Airlines deal was found by Cheapflights users on 7/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/43:22 pm
FLO
-
MCO
1 stop4h 45m
American Airlines
Mon 9/74:21 pm
MCO
-
FLO
1 stop6h 38m
American Airlines
Deal found 7/22$525
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/213:22 pm
FLO
-
MCO
1 stop4h 45m
American Airlines
Tue 8/2510:57 am
MCO
-
FLO
1 stop3h 59m
American Airlines
Deal found 7/24$532
This American Airlines deal was found by Cheapflights users on 7/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 8/76:22 am
FLO
-
MCO
1 stop6h 09m
American Airlines
Tue 8/115:36 pm
MCO
-
FLO
1 stop5h 23m
American Airlines
Deal found 7/23$562
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/292:35 pm
FLO
-
MCO
1 stop4h 09m
American Airlines
Tue 8/49:01 am
MCO
-
FLO
1 stop5h 09m
American Airlines
Deal found 7/25$587
This American Airlines deal was found by Cheapflights users on 7/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:22 am
FLO
-
MCO
2 stops13h 06m
American Airlines
Mon 9/149:32 am
MCO
-
FLO
1 stop3h 46m
American Airlines
Deal found 7/24$595
This American Airlines deal was found by Cheapflights users on 7/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/63:22 pm
FLO
-
MCO
1 stop4h 45m
American Airlines
Mon 8/109:10 am
MCO
-
FLO
1 stop5h 46m
American Airlines
Deal found 7/21$597
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/305:17 am
FLO
-
MCO
1 stop3h 56m
American Airlines
Sat 8/19:01 am
MCO
-
FLO
1 stop5h 09m
American Airlines
Deal found 7/25$616
This American Airlines deal was found by Cheapflights users on 7/25. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/302:35 pm
FLO
-
MCO
1 stop4h 09m
American Airlines
Mon 8/310:03 am
MCO
-
FLO
1 stop4h 07m
American Airlines
Deal found 7/25$645

Find flight deals from Florence to Kissimmee

Keep the following information in mind while searching for Florence to Kissimmee flight deals. Data was last updated July 25, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$491
(American Airlines)

One-way from

$427
(American Airlines)
Provider with most accurate pricing for Florence-Orlando (ORL) flight deals.
Search Deals
Provider most trusted by Cheapflights users for Florence-Orlando (ORL) flights.
Search Deals
From Florence to Kissimmee
Search Deals
One-way flight from Florence to Kissimmee
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Florence to Kissimmee that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 25, 2026.
Use the filters below to find and compare flights from Florence to Kissimmee that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip
Quickest round-trip

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Fri 8/21

3:22 pm-8:07 pm

1 stop4h 45m

Orlando

Tue 8/25

10:57 am-2:56 pm

1 stop3h 59m

$532

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Fri 8/7

6:22 am-12:31 pm

1 stop6h 09m

Orlando

Tue 8/11

5:36 pm-10:59 pm

1 stop5h 23m

$562

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Mon 9/7

6:22 am-7:28 pm

2 stops13h 06m

Orlando

Mon 9/14

9:32 am-1:18 pm

1 stop3h 46m

$595

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Fri 9/4

6:22 am-6:17 pm

2 stops11h 55m

Orlando

Mon 9/7

11:31 am-10:59 pm

2 stops11h 28m

$711

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Thu 8/6

3:22 pm-11:41 pm

2 stops8h 19m

Orlando

Mon 8/10

9:10 am-2:56 pm

1 stop5h 46m

$750

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Sun 8/9

2:37 pm-6:40 pm

1 stop4h 03m

Orlando

Thu 8/13

5:36 pm-10:59 pm

1 stop5h 23m

$863
Cheapest one-way
Quickest one-way

FlorenceOrlando

FLO - MCO

FLOMCO

Florence

Mon 9/7

6:22 am-12:31 pm

1 stop6h 09m

$427

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/20

Sorted by cheapest first

Best time to book a flight from Florence to Kissimmee

Have a flexible travel schedule? Discover the best time to fly to Kissimmee from Florence with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Florence to Kissimmee

No data available for this route at this time. Please check back soon.

Related info for your journey

Find useful and relevant information for your journey from Florence to Kissimmee. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Florence to Kissimmee?

    If you book a flight to Kissimmee from Florence, you will be flying from Florence, which is the city’s only airport. Florence (FLO) is located 2.3 mi from the center of Florence. There are 0 flights from Florence to Kissimmee per day from 0 different airlines.

  • How long is the flight from Florence, South Carolina to Kissimmee?

    Airlines like American Airlines fly from Florence, South Carolina to Kissimmee in about 4h 45m. The time it takes to get you to your destination can typically vary by up to . There are 408 mi between Florence, South Carolina and Kissimmee.

  • Can I find deals for flights from Florence to Kissimmee that include hotel bookings?

    Yes. In addition to deals on Florence to Kissimmee flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Florence to Kissimmee?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Florence to Kissimmee.

  • Can I find deals for business class flights from Florence to Kissimmee?

    Yes. Cheapflights offers flight deals from Florence to Kissimmee by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.

Alternative routes for Florence to Kissimmee

See prices for flight routes from nearby airports that may be better suited for you.
Charlotte to Fort Lauderdale flights
Charlotte to Miami flights
Charlotte to Orlando flights
Charlotte to Tampa flights
Charleston to Miami flights
Charlotte to West Palm Beach flights
Charleston to Fort Lauderdale flights
Columbia to Orlando flights
Greenville to Miami flights
Charlotte to Fort Myers flights
Myrtle Beach to Fort Lauderdale flights
Charlotte to Key West flights
Columbia to Miami flights
Charleston to Orlando flights
Charlotte to Jacksonville flights
Charlotte to Sarasota flights
Myrtle Beach to Miami flights
Greenville to Tampa flights
Greenville to Fort Lauderdale flights
Charleston to Tampa flights
Myrtle Beach to Orlando flights
Charlotte to Pensacola flights
Savannah to Miami flights
Charlotte to Panama City flights
Greenville to Orlando flights
Charlotte to Daytona Beach flights
Columbia to Tampa flights
Greenville to Jacksonville flights
Columbia to Key West flights
Myrtle Beach to Tampa flights
Charlotte to Tallahassee flights
Myrtle Beach to Key West flights
Greenville to Key West flights
Greenville to Sarasota flights
Savannah to Orlando flights
Columbia to Fort Lauderdale flights
Greenville to Panama City flights
Columbia to Pensacola flights
Charleston to Key West flights
Charleston to West Palm Beach flights
Greenville to St Petersburg flights
Greenville to West Palm Beach flights
Myrtle Beach to Sarasota flights
Savannah to Key West flights
Savannah to Fort Lauderdale flights
Columbia to Fort Myers flights
Greenville to Pensacola flights
Myrtle Beach to Fort Myers flights

100% Free

Cheapflights is completely free to use, so you can start saving the moment you arrive.

Book with Flexibility

Our users can plan ahead with confidence and find flights with no change fees

Travel Smart

Millions of people come to us for their flight needs every year. We help make travel planning easy by providing useful insights and data-driven graphs that can inform your decisions.
Site
©2026 Cheapflights