$222+ Cheap flights from Mississippi to Key West (EYW)
This is the cheapest round-trip flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/30. Fares are subject to change and may not be available on all flights or dates of travel.
JAN — EYW
Sep 13 — Sep 201
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Mississippi to Key West with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Mississippi to Key West
Cheapest
Best
Last-minute
One-way
Cheapest flights from Mississippi to Key WestExplore the most affordable flight options available from Mississippi to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
Explore the most affordable flight options available from Mississippi to Key West. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:58 pm -
1 stop12h 04m
Sun 11/19:12 am -
1 stop6h 08m
Deal found 8/12![Multiple Airlines logo]()
$222
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:58 pm -
1 stop12h 26m
Thu 11/58:54 pm -
1 stop11h 11m
Deal found 8/12![Multiple Airlines logo]()
$227
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:05 pm -
1 stop21h 08m
Sun 11/19:12 am -
1 stop6h 08m
Deal found 8/12![Allegiant Air logo]()
$229
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:05 pm -
1 stop21h 08m
Thu 11/58:54 pm -
1 stop11h 11m
Deal found 8/12![Allegiant Air logo]()
$235
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:46 pm -
1 stop13h 38m
Sun 11/110:59 am -
1 stop9h 06m
Deal found 8/10![Breeze Airways logo]()
$242
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/117:45 pm -
1 stop17h 19m
Sun 10/1810:59 am -
1 stop9h 06m
Deal found 8/12![Multiple Airlines logo]()
$251
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/307:58 pm -
1 stop12h 04m
Wed 11/410:04 am -
1 stop27h 15m
Deal found 8/12![Multiple Airlines logo]()
$252
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/13:10 pm -
1 stop21h 44m
Thu 11/58:54 pm -
1 stop11h 11m
Deal found 8/12![Allegiant Air logo]()
$257
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/293:05 pm -
1 stop21h 08m
Wed 11/410:04 am -
1 stop27h 15m
Deal found 8/12![Multiple Airlines logo]()
$260
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:46 pm -
1 stop13h 38m
Sun 10/410:59 am -
1 stop9h 06m
Deal found 8/12![Breeze Airways logo]()
$264
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/267:58 pm -
1 stop15h 38m
Fri 10/3012:59 pm -
1 stop7h 19m
Deal found 8/12![Breeze Airways logo]()
$270
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/18:27 pm -
2 stops16h 27m
Thu 11/58:54 pm -
1 stop11h 11m
Deal found 8/12![Multiple Airlines logo]()
$279
Best flights from Mississippi to Key WestDiscover carefully curated flight deals from Mississippi to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
Discover carefully curated flight deals from Mississippi to Key West that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 14, 2026.
This Breeze Airways deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/306:46 pm -
1 stop13h 38m
Sun 11/110:59 am -
1 stop9h 06m
Deal found 8/10![Breeze Airways logo]()
$242
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 46m
Sat 9/197:40 am -
1 stop4h 07m
Deal found 8/13![Delta logo]()
$309
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 1/263:42 pm -
1 stop5h 05m
Sat 1/306:43 pm -
1 stop5h 47m
Deal found 8/13![American Airlines logo]()
$319
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/272:50 pm -
1 stop19h 37m
Sun 8/307:53 pm -
1 stop23h 30m
Deal found 8/13![Multiple Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
1 stop7h 29m
Sat 10/312:50 pm -
1 stop9h 49m
Deal found 8/12![United Airlines logo]()
$506
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/26:46 pm -
1 stop13h 38m
Sun 10/410:59 am -
1 stop9h 06m
Deal found 8/12![Breeze Airways logo]()
$264
This Breeze Airways deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Breeze Airways is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/297:45 pm -
1 stop13h 34m
Sun 11/110:59 am -
1 stop9h 06m
Deal found 8/11![Breeze Airways logo]()
$283
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:26 am -
1 stop5h 54m
Sat 8/297:40 am -
1 stop6h 07m
Deal found 8/10![Delta logo]()
$349
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:00 am -
1 stop5h 52m
Wed 9/211:48 am -
1 stop5h 28m
Deal found 8/14![Delta logo]()
$365
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/258:10 am -
1 stop7h 08m
Sat 8/2911:40 am -
2 stops9h 26m
Deal found 8/10![American Airlines logo]()
$433
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:30 am -
1 stop6h 53m
Tue 9/227:40 am -
1 stop5h 52m
Deal found 8/10![Delta logo]()
$383
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/3012:50 pm -
1 stop7h 57m
Wed 2/34:24 pm -
2 stops8h 06m
Deal found 8/9![American Airlines logo]()
$442
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/111:32 pm -
1 stop5h 28m
Sat 9/1911:42 am -
1 stop4h 19m
Deal found 8/12![Delta logo]()
$388
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/128:14 am -
2 stops10h 03m
Sat 9/196:27 pm -
1 stop5h 23m
Deal found 8/13![American Airlines logo]()
$445
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:32 pm -
1 stop5h 28m
Sat 9/1911:42 am -
1 stop4h 19m
Deal found 8/11![Delta logo]()
$388
This American Airlines deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/296:35 am -
2 stops11h 05m
Wed 9/24:50 pm -
1 stop6h 49m
Deal found 8/14![American Airlines logo]()
$457
This United Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/266:14 pm -
2 stops18h 38m
Sat 10/312:50 pm -
1 stop9h 49m
Deal found 8/12![United Airlines logo]()
$628
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/101:32 pm -
1 stop5h 28m
Sat 9/1911:42 am -
1 stop4h 19m
Deal found 8/11![Delta logo]()
$403
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:11 am -
2 stops9h 47m
Mon 11/26:26 pm -
1 stop5h 15m
Deal found 8/13![American Airlines logo]()
$488
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/276:00 am -
1 stop3h 47m
Tue 11/37:40 am -
1 stop4h 18m
Deal found 8/12![Delta logo]()
$423
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/67:05 am -
1 stop8h 06m
Sat 9/126:31 pm -
1 stop5h 01m
Deal found 8/9![American Airlines logo]()
$496
This United Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 1/96:55 pm -
2 stops19h 11m
Wed 1/134:05 pm -
2 stops26h 33m
Deal found 8/11![United Airlines logo]()
$777
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/212:06 pm -
1 stop6h 51m
Wed 9/97:40 am -
1 stop4h 42m
Deal found 8/9![Delta logo]()
$457
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/257:40 am -
1 stop7h 38m
Sat 8/2911:40 am -
2 stops11h 50m
Deal found 8/10![American Airlines logo]()
$503
This Delta deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/121:32 pm -
1 stop5h 28m
Sun 9/207:40 am -
1 stop6h 12m
Deal found 8/11![Delta logo]()
$459
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/166:44 am -
1 stop5h 27m
Sun 9/207:22 pm -
1 stop5h 29m
Deal found 8/10![American Airlines logo]()
$565
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/301:04 pm -
1 stop5h 57m
Sun 11/17:40 am -
1 stop5h 09m
Deal found 8/10![Delta logo]()
$478
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/276:35 am -
2 stops12h 04m
Mon 8/314:50 pm -
1 stop6h 49m
Deal found 8/12![American Airlines logo]()
$567
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 9/76:00 am -
1 stop6h 00m
Fri 9/112:00 pm -
1 stop19h 30m
Deal found 8/9![Delta logo]()
$513
This American Airlines deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 10/38:16 am -
2 stops10h 01m
Thu 10/84:45 pm -
1 stop8h 11m
Deal found 8/9![American Airlines logo]()
$579
Last-minute flights from Mississippi to Key WestDiscover last-minute flight deals from Mississippi to Key West. Data last updated August 14, 2026 and is based on user searches.
Discover last-minute flight deals from Mississippi to Key West. Data last updated August 14, 2026 and is based on user searches.
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/221:27 pm -
1 stop5h 30m
Wed 8/267:40 am -
1 stop6h 07m
Deal found 8/12![Delta logo]()
$379
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 8/2510:26 am -
1 stop5h 54m
Sat 8/297:40 am -
1 stop6h 07m
Deal found 8/10![Delta logo]()
$349
This Kiwi.com deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:50 am -
2 stops7h 23m
Mon 8/311:11 pm -
1 stop6h 12m
Deal found 8/12![Breeze Airways logo]()
$316
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/2710:50 am -
2 stops7h 23m
Sun 8/307:53 pm -
1 stop23h 30m
Deal found 8/13![Breeze Airways logo]()
$359
This Delta deal was found by Cheapflights users on 8/14. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/298:00 am -
1 stop5h 52m
Wed 9/211:48 am -
1 stop5h 28m
Deal found 8/14![Delta logo]()
$365
This Delta deal was found by Cheapflights users on 8/9. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/16:00 am -
1 stop6h 00m
Sat 9/57:40 am -
1 stop4h 40m
Deal found 8/9![Delta logo]()
$319
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/126:00 am -
1 stop3h 46m
Sat 9/197:40 am -
1 stop4h 07m
Deal found 8/13![Delta logo]()
$309
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/151:03 pm -
1 stop5h 57m
Sat 9/197:40 am -
1 stop5h 06m
Deal found 8/10![Delta logo]()
$337
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/174:35 pm -
2 stops16h 44m
Thu 9/2410:59 am -
1 stop9h 26m
Deal found 8/10![Multiple Airlines logo]()
$336
This Delta deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 9/189:30 am -
1 stop6h 53m
Tue 9/227:40 am -
1 stop5h 52m
Deal found 8/10![Delta logo]()
$383
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 9/1912:10 pm -
1 stop6h 50m
Tue 9/226:19 pm -
1 stop6h 01m
Deal found 8/12![Delta logo]()
$334
This Kiwi.com deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 9/203:59 pm -
2 stops19h 20m
Thu 9/245:09 pm -
1 stop27h 09m
Deal found 8/13![Multiple Airlines logo]()
$377
One-way flights from Mississippi to Key WestSearch for one-way flight options from Mississippi to Key West. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
Search for one-way flight options from Mississippi to Key West. Find affordable one-way fares based on user searches. Data last updated August 14, 2026.
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/178:50 pm -
1 stop17h 17m
Deal found 8/10![Allegiant Air logo]()
$224
This American Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/2512:43 pm -
1 stop5h 04m
Deal found 8/10![American Airlines logo]()
$274
This Delta deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/281:46 pm -
1 stop5h 15m
Deal found 8/13![Delta logo]()
$274
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/1710:30 am -
1 stop5h 53m
Deal found 8/12![Delta logo]()
$333
This American Airlines deal was found by Cheapflights users on 8/11. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 9/178:14 am -
2 stops10h 03m
Deal found 8/11![American Airlines logo]()
$338
This Delta deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Delta is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/211:46 am -
1 stop4h 34m
Deal found 8/12![Delta logo]()
$363
This American Airlines deal was found by Cheapflights users on 8/12. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 9/28:15 am -
2 stops10h 24m
Deal found 8/12![American Airlines logo]()
$368
This American Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/286:11 am -
2 stops9h 47m
Deal found 8/13![American Airlines logo]()
$374
This Kiwi.com deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure Kiwi.com is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 12/172:22 pm -
2 stops25h 35m
Deal found 8/10![Multiple Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 8/10. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 11/256:55 am -
3 stops31h 34m
Deal found 8/10![United Airlines logo]()
$525
This United Airlines deal was found by Cheapflights users on 8/13. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/287:00 am -
3 stops31h 29m
Deal found 8/13![United Airlines logo]()
$695
Find flight deals from Mississippi to Key West
Keep the following information in mind while searching for Mississippi to Key West flight deals. Data was last updated August 14, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $222 (Kiwi.com) |
Cheapflights Fare Finder
Customize your flight search to find flights from Mississippi to Key West that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
Use the filters below to find and compare flights from Mississippi to Key West that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
GulfportKey West
GPT Gulfport Biloxi Regional - EYW Key West
GPTEYW
Gulfport Biloxi Regional
Fri 10/30
6:46 pm-9:24 am
1 stop13h 38m
Key West
Sun 11/1
10:59 am-7:05 pm
1 stop9h 06m
$242
GulfportKey West
GPT Gulfport Biloxi Regional - EYW Key West
GPTEYW
Gulfport Biloxi Regional
Fri 10/2
6:46 pm-9:24 am
1 stop13h 38m
Key West
Sun 10/4
10:59 am-7:05 pm
1 stop9h 06m
$264
GulfportKey West
GPT Gulfport Biloxi Regional - EYW Key West
GPTEYW
Gulfport Biloxi Regional
Thu 10/29
7:45 pm-10:19 am
1 stop13h 34m
Key West
Sun 11/1
10:59 am-7:05 pm
1 stop9h 06m
$283
Quickest round-trip
MemphisKey West
MEM Memphis - EYW Key West
MEMEYW
Memphis
Sat 9/12
6:00 am-10:46 am
1 stop3h 46m
Key West
Sat 9/19
7:40 am-10:47 am
1 stop4h 07m
$309
JacksonKey West
JAN Jackson-Evers Intl - EYW Key West
JANEYW
Jackson-Evers Intl
Tue 1/26
3:42 pm-9:47 pm
1 stop5h 05m
Key West
Sat 1/30
6:43 pm-11:30 pm
1 stop5h 47m
$319
Baton RougeKey West
BTR Baton Rouge Ryan - EYW Key West
BTREYW
Baton Rouge Ryan
Tue 8/25
10:26 am-5:20 pm
1 stop5h 54m
Key West
Sat 8/29
7:40 am-12:47 pm
1 stop6h 07m
$349
JacksonKey West
JAN Jackson-Evers Intl - EYW Key West
JANEYW
Jackson-Evers Intl
Sat 8/29
8:00 am-2:52 pm
1 stop5h 52m
Key West
Wed 9/2
11:48 am-4:16 pm
1 stop5h 28m
$365
MemphisKey West
MEM Memphis - EYW Key West
MEMEYW
Memphis
Fri 9/18
9:30 am-5:23 pm
1 stop6h 53m
Key West
Tue 9/22
7:40 am-12:32 pm
1 stop5h 52m
$383
Baton RougeKey West
BTR Baton Rouge Ryan - EYW Key West
BTREYW
Baton Rouge Ryan
Fri 9/11
1:32 pm-8:00 pm
1 stop5h 28m
Key West
Sat 9/19
11:42 am-3:01 pm
1 stop4h 19m
$388
Baton RougeKey West
BTR Baton Rouge Ryan - EYW Key West
BTREYW
Baton Rouge Ryan
Sat 9/12
1:32 pm-8:00 pm
1 stop5h 28m
Key West
Sat 9/19
11:42 am-3:01 pm
1 stop4h 19m
$388
Showing 1-10 of 38 resultsSorted by cheapest first
Best time to book a flight from Mississippi to Key West
Have a flexible travel schedule? Discover the best time to fly to Key West from Mississippi with our price prediction graph.
MEM-EYW
MOB-EYW
JAN-EYW
BTR-EYW
GPT-EYW
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Mississippi to Key West
USMS-EYW
MEM-EYW
MOB-EYW
JAN-EYW
BTR-EYW
No data available for this route at this time. Please check back soon.
Related info for your journey
Find useful and relevant information for your journey from Mississippi to Key West. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Key West flight routes
Other flight options
Popular flights
Top destinations
Alternative routes for Mississippi to Key West
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key West by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Mississippi to Key West by cabin class
Find flights from Mississippi to Key West, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Other flights to Key West
Explore flights to Key West departing from other origins. Flights are based on user searches made on Cheapflights and were last updated on August 14, 2026.
Mississippi and Key West flights
Browse other Mississippi and Key West flight options. Last updated on August 14, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Mississippi to Key West flights
Consider these flights traveling from Mississippi to Key West.
Top 2 airlines flying from Mississippi to Key West
Discover the top 2 airlines that operate flights from Mississippi to Key West. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated August 14, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$298 | Average$501 | FlexibilityNo cancel fee | On-time71% | |
| Cheapest$308 | Average$546 | FlexibilityNo cancel fee | On-timeN/A |