How long is the flight from Columbia, Missouri to Key Largo?

There are many flights that can get you from Columbia, Missouri to Key Largo in 11h 37m. Fly via United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo.

In terms of precipitation, rainfall in Key Largo ranges from 1.6 - 9.9 inches per month. September is typically the wettest month, when rainfall can reach 9.9 in. January is typically the driest time to visit Key Largo when rainfall is around 1.6 in.

If weather is an important factor for your trip to Key Largo, use this chart to help with planning. For those seeking warmer temperatures, July is the ideal time of year to visit, when temperatures reach an average of 84.2 F. Travelers looking to avoid the cold should look outside of January, when temperatures are typically at their lowest (around 68.0 F).

What is the cheapest time of day to fly from COU to KE9?

Regardless of the time of day you decide to fly, the ticket price will remain around the same. Book flights from Columbia, Missouri to Key Largo as you normally would.

What airport do you fly from for flights from Columbia to Key Largo?

Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 2 airlines have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

How can I find direct flights from Columbia to Key Largo?

After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

Can I find deals for business class flights from Columbia to Key Largo?

Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

$303+ Cheap Flights from Columbia, MO to Key Largo

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Cheap flight deals from Columbia to Key Largo

Cheapest

Best

Last-minute

One-way

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.

Wed 9/96:15 am -

2 stops11h 37m

Wed 9/233:57 pm -

1 stop7h 58m

Deal found 8/26

$349

Sat 10/176:15 am -

1 stop7h 44m

Sat 10/2411:25 am -

2 stops12h 30m

Deal found 8/24

$350

Tue 9/86:15 am -

1 stop7h 36m

Sat 9/1211:30 am -

2 stops10h 09m

Deal found 8/25

$374

Tue 9/226:15 am -

1 stop7h 36m

Fri 10/24:01 pm -

1 stop7h 54m

Deal found 8/26

$398

Sat 12/1211:25 am -

2 stops9h 51m

Sat 12/199:00 am -

1 stop6h 28m

Deal found 8/24

$404

Sat 10/36:15 am -

1 stop7h 44m

Tue 10/64:01 pm -

1 stop7h 54m

Deal found 8/24

$408

Sat 10/1710:40 am -

1 stop11h 28m

Sat 10/248:37 am -

1 stop13h 18m

Deal found 8/24

$423

Sat 9/126:15 am -

1 stop7h 36m

Tue 9/153:57 pm -

1 stop7h 58m

Deal found 8/24

$433

Best flights from Columbia to Key Largo
Discover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.

Wed 9/96:15 am -

2 stops11h 37m

Wed 9/233:57 pm -

1 stop7h 58m

Deal found 8/26

$349

Tue 9/86:15 am -

1 stop7h 36m

Sat 9/1211:30 am -

2 stops10h 09m

Deal found 8/24

$374

Sat 10/36:15 am -

1 stop7h 44m

Tue 10/64:01 pm -

1 stop7h 54m

Deal found 8/26

$408

Sat 12/1211:25 am -

2 stops9h 51m

Sat 12/191:56 pm -

2 stops8h 56m

Deal found 8/26

$409

Wed 10/146:15 am -

2 stops11h 37m

Sat 10/248:54 am -

2 stops12h 39m

Deal found 8/25

$419

Last-minute flights from Columbia to Key Largo
Discover last-minute flight deals from Columbia to Key Largo. Data last updated August 27, 2026 and is based on user searches.

Thu 8/276:15 am -

1 stop7h 39m

Sat 8/293:57 pm -

1 stop7h 58m

Deal found 8/23

$478

Tue 9/86:15 am -

1 stop7h 36m

Sat 9/1211:30 am -

2 stops10h 09m

Deal found 8/25

$374

Wed 9/96:15 am -

2 stops11h 37m

Wed 9/233:57 pm -

1 stop7h 58m

Deal found 8/26

$349

Sat 9/126:15 am -

1 stop7h 36m

Mon 9/143:57 pm -

1 stop7h 58m

Deal found 8/24

$433

Sat 9/126:15 am -

1 stop7h 36m

Tue 9/1511:26 am -

2 stops12h 29m

Deal found 8/24

$439

Thu 9/176:15 am -

1 stop7h 36m

Sun 9/203:57 pm -

1 stop7h 58m

Deal found 8/26

$419

Tue 9/226:15 am -

1 stop7h 36m

Fri 10/24:01 pm -

1 stop7h 54m

Deal found 8/26

$398

Fri 9/2510:38 am -

1 stop11h 37m

Fri 10/210:10 pm -

1 stop12h 46m

Deal found 8/26

$463

Find flight deals from Columbia to Key Largo

Most accurate provider	FlightHub 3 stars
Most trusted provider	FlightHub 3 stars
Round-trip from	$349 (United Airlines)
One-way from	$303 (United Airlines)
Popular in	May
Cheapest in	July
Average price	$398

Provider with most accurate pricing for Columbia Regional-Miami flight deals.

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Provider most trusted by Cheapflights users for Columbia Regional-Miami flights.

Search Deals

From Columbia Regional to Key Largo

Search Deals

One-way flight from Columbia Regional to Key Largo

Search Deals

Highest demand for flights based on searches. 12% potential increase in price ($72 potential increase over avg. RT price).

Search Deals

Cheapest flight prices on average. 2% potential price decrease ($15 potential savings vs. average RT price).

Search Deals

Average for round-trip flights in August 2026

Search Deals

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Wed 9/9

6:15 am-6:52 pm

2 stops11h 37m

Miami

Wed 9/23

3:57 pm-10:55 pm

1 stop7h 58m

$349

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Tue 9/8

6:15 am-2:51 pm

1 stop7h 36m

Miami

Sat 9/12

11:30 am-8:39 pm

2 stops10h 09m

$374

Quickest round-trip

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Sat 10/3

6:15 am-2:59 pm

1 stop7h 44m

Miami

Tue 10/6

4:01 pm-10:55 pm

1 stop7h 54m

$408

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Sat 12/12

11:25 am-10:16 pm

2 stops9h 51m

Miami

Sat 12/19

1:56 pm-9:52 pm

2 stops8h 56m

$409

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Wed 10/14

6:15 am-6:52 pm

2 stops11h 37m

Miami

Sat 10/24

8:54 am-8:33 pm

2 stops12h 39m

$419

Cheapest one-way

Quickest one-way

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Sun 11/1

8:00 am-3:03 pm

1 stop6h 03m

$303

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Wed 11/4

10:24 am-10:21 pm

1 stop10h 57m

$329

ColumbiaMiami

COU Columbia Regional - MIA Miami

COUMIA

Columbia Regional

Wed 11/4

8:00 am-10:15 pm

2 stops13h 15m

$354

Flights are sorted by cheapest round-trip flights first.

Deals found on 8/25

Sorted by cheapest first

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.

COU-MIA

Estimated round-trip price

Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo

COU-KE9

COU-MIA

No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Key Largo

See what other customers who have flown with United Airlines and American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

United Airlines

7.4

Good

10,121 reviews

Reviews

1 / 20

2.0

Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

United Airlines

7.4

Good

10,121 reviews

United Airlines

7.4

Good

10,121 reviews

Reviews

1 / 20

2.0

Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

American Airlines

7.1

Good

11,995 reviews

United Airlines

7.4

Good

10,121 reviews

Reviews

1 / 20

2.0

Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

What airport do you fly from for flights from Columbia to Key Largo?
Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 2 airlines have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.
How long is the flight from Columbia, Missouri to Key Largo?
There are many flights that can get you from Columbia, Missouri to Key Largo in 11h 37m. Fly via United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo.
Can I find deals for flights from Columbia to Key Largo that include hotel bookings?
Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.
How can I find direct flights from Columbia to Key Largo?
After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.
Can I find deals for business class flights from Columbia to Key Largo?
Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

Browse thousands of different options on Cheapflights for your next trip

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Top 2 airlines flying from Columbia to Key Largo

Airline	Cheapest	Average	Flexibility	On-time
United Airlines	Cheapest$268	Average$423	FlexibilityNo cancel fee	On-time69%
American Airlines	Cheapest$333	Average$553	FlexibilityNo cancel fee	On-time71%

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$303+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 11/1. Fares are subject to change and may not be available on all flights or dates of travel.

Find cheap flights from Columbia to Key Largo with Cheapflights

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Cheap flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key LargoExplore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.

Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.

Best flights from Columbia to Key LargoDiscover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.

Discover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.

Last-minute flights from Columbia to Key LargoDiscover last-minute flight deals from Columbia to Key Largo. Data last updated August 27, 2026 and is based on user searches.

Discover last-minute flight deals from Columbia to Key Largo. Data last updated August 27, 2026 and is based on user searches.

One-way flights from Columbia to Key LargoSearch for one-way flight options from Columbia to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.

Search for one-way flight options from Columbia to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.

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Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.

Cheapflights Insights

Reviews of airlines servicing Key Largo

See what other customers who have flown with United Airlines and American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.

Related info for your journey

What airport do you fly from for flights from Columbia to Key Largo?

How long is the flight from Columbia, Missouri to Key Largo?

Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

How can I find direct flights from Columbia to Key Largo?

Can I find deals for business class flights from Columbia to Key Largo?

Browse thousands of different options on Cheapflights for your next trip

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Alternative routes for Columbia to Key Largo

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Complete your trip

Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.

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Find flights from Columbia to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.

Columbia and Key Largo flights

Browse other Columbia and Key Largo flight options. Last updated on August 27, 2026.

Other flights from Columbia

Browse through other flights departing from Columbia. Flights are based on user searches made on Cheapflights and were last updated on August 27, 2026.

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Check out other popular destinations found by fellow travelers in 2026

Columbia to Key Largo flights

Consider these flights traveling from Columbia to Key Largo.

Top 2 airlines flying from Columbia to Key Largo

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Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on August 27, 2026.

Best flights from Columbia to Key Largo
Discover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated August 27, 2026.

Last-minute flights from Columbia to Key Largo
Discover last-minute flight deals from Columbia to Key Largo. Data last updated August 27, 2026 and is based on user searches.

One-way flights from Columbia to Key Largo
Search for one-way flight options from Columbia to Key Largo. Find affordable one-way fares based on user searches. Data last updated August 27, 2026.