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Key Largo

$279+ Cheap flights from Columbia, MO (COU) to Key Largo, FL

This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 7/22. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
Aug 7 — Aug 141
Fri 8/7
Fri 8/14
1 adult, Economy
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Cheap flight deals from Columbia to Key Largo

Cheapest flights from Columbia to Key Largo
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on July 8, 2026.

This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/236:15 am
COU
-
MIA
1 stop7h 39m
United Airlines
Sat 8/293:57 pm
MIA
-
COU
1 stop7h 58m
United Airlines
Deal found 7/3$308
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 7/233:25 pm
COU
-
MIA
1 stop6h 02m
United Airlines
Fri 8/75:32 pm
MIA
-
COU
1 stop7h 01m
United Airlines
Deal found 7/7$333
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/166:15 am
COU
-
MIA
1 stop7h 39m
United Airlines
Sat 8/223:57 pm
MIA
-
COU
1 stop7h 58m
United Airlines
Deal found 7/7$358
This United Airlines deal was found by Cheapflights users on 7/7. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/13:25 pm
COU
-
MIA
1 stop6h 02m
United Airlines
Tue 8/44:10 pm
MIA
-
COU
1 stop8h 23m
United Airlines
Deal found 7/7$360
This United Airlines deal was found by Cheapflights users on 7/5. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 7/288:00 am
COU
-
MIA
1 stop5h 57m
United Airlines
Sat 8/15:32 pm
MIA
-
COU
1 stop7h 01m
United Airlines
Deal found 7/5$364
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 10/3011:15 am
COU
-
MIA
1 stop6h 30m
United Airlines
Sat 11/79:00 am
MIA
-
COU
1 stop6h 29m
United Airlines
Deal found 7/4$374
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 8/2210:55 am
COU
-
MIA
2 stops11h 49m
United Airlines
Sat 8/293:57 pm
MIA
-
COU
1 stop7h 58m
United Airlines
Deal found 7/4$375
This United Airlines deal was found by Cheapflights users on 7/3. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 7/313:25 pm
COU
-
MIA
1 stop6h 02m
United Airlines
Fri 8/75:32 pm
MIA
-
COU
1 stop7h 01m
United Airlines
Deal found 7/3$381
This United Airlines deal was found by Cheapflights users on 7/4. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 12/165:00 am
COU
-
MIA
1 stop5h 53m
United Airlines
Mon 12/211:00 pm
MIA
-
COU
2 stops10h 58m
United Airlines
Deal found 7/4$386

Find flight deals from Columbia to Key Largo

Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated July 8, 2026.

Most accurate provider

FlightHub
3 stars

Most trusted provider

FlightHub
3 stars

Round-trip from

$308
(United Airlines)

One-way from

$279
(Kiwi.com)

Popular in

December

Cheapest in

January

Average price

$398
Provider with most accurate pricing for Columbia Regional-Miami flight deals.
Search Deals
Provider most trusted by Cheapflights users for Columbia Regional-Miami flights.
Search Deals
From Columbia Regional to Key Largo
Search Deals
One-way flight from Columbia Regional to Key Largo
Search Deals
Highest demand for flights based on searches. 4% potential increase in price ($25 potential increase over avg. RT price).
Search Deals
Cheapest flight prices on average. 3% potential price decrease ($19 potential savings vs. average RT price).
Search Deals
Average for round-trip flights in July 2026
Search Deals

Cheapflights Fare Finder

 
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.

Fly from

Fly to

Route

Depart

Return

Price

Cheapest round-trip

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 8/22

6:15 am-2:54 pm

1 stop7h 39m

Miami

Sat 8/29

3:57 pm-10:55 pm

1 stop7h 58m

$308

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sun 8/23

6:15 am-2:54 pm

1 stop7h 39m

Miami

Sat 8/29

11:30 am-8:59 pm

2 stops10h 29m

$336

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sun 8/16

6:15 am-2:54 pm

1 stop7h 39m

Miami

Sat 8/22

3:57 pm-10:55 pm

1 stop7h 58m

$358

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 8/22

6:15 am-2:54 pm

1 stop7h 39m

Miami

Wed 8/26

3:57 pm-10:55 pm

1 stop7h 58m

$398

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 8/29

6:15 am-2:54 pm

1 stop7h 39m

Miami

Wed 9/2

3:57 pm-10:55 pm

1 stop7h 58m

$398
Quickest round-trip

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Wed 7/29

3:25 pm-10:27 pm

1 stop6h 02m

Miami

Mon 8/3

5:32 pm-11:33 pm

1 stop7h 01m

$448

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Fri 8/7

6:00 am-8:28 pm

1 stop13h 28m

Miami

Mon 8/17

5:00 am-6:03 pm

1 stop14h 03m

$465
Cheapest one-way

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Sat 7/18

3:25 pm-10:27 pm

1 stop6h 02m

$373

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Mon 7/20

3:25 pm-10:27 pm

1 stop6h 02m

$373
Quickest one-way

ColumbiaMiami

COU - MIA

COUMIA

Columbia Regional

Thu 7/23

8:00 am-2:57 pm

1 stop5h 57m

$373

Flights are sorted by cheapest round-trip flights first.

Deals found on 7/3

Showing 1-10 of 17 resultsSorted by cheapest first
1
2

Best time to book a flight from Columbia to Key Largo

Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.

Cheapflights Insights

Everything you need to know about your flight from Columbia to Key Largo
No data available for this route at this time. Please check back soon.

Reviews of airlines servicing Key Largo

Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated July 8, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
United Airlines
7.4
Good
9,948 reviews

Crew

8.1

Overall

7.4

Food

6.7

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
United Airlines
7.4
Good
9,948 reviews
United Airlines
7.4
Good
9,948 reviews

Crew

8.1

Overall

7.4

Food

6.7

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000
American Airlines
7.1
Good
11,783 reviews
United Airlines
7.4
Good
9,948 reviews

Crew

8.1

Overall

7.4

Food

6.7

Boarding

7.7

Entertainment

7.1

Comfort

7.3

Reviews

1 / 20
2.0
Mediocre

Sebrena,Oct 2025

IAH - RSW

The worst that I have ever experienced in my life so bad if it was free I'm not ever going to use your Airline again I dont believe ..... very disappointed 😞 😔0000000000000

Related info for your journey

Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.

  • What airport do you fly from for flights from Columbia to Key Largo?

    Columbia Regional (COU), located 11.1 mi from the city center, is the airport you fly out of when you book flights from Columbia to Key Largo. 2 airlines have flights from Columbia Regional to Key Largo on a regular basis. Booking flights from Columbia Regional to Key Largo should not be difficult; the airport handles an average of 0 outbound flights to Key Largo per day.

  • How long is the flight from Columbia, Missouri to Key Largo?

    There are many flights that can get you from Columbia, Missouri to Key Largo in 7h 39m. Fly via United Airlines to get the fastest option. There are 1135 mi between Columbia, Missouri and Key Largo.

  • Can I find deals for flights from Columbia to Key Largo that include hotel bookings?

    Yes. In addition to deals on Columbia to Key Largo flights, Cheapflights offers vacation packages that include both flights and hotel.

  • How can I find direct flights from Columbia to Key Largo?

    After entering your origin and destination, apply the non-stop filter on the search result page to find direct flights from Columbia to Key Largo.

  • Can I find deals for business class flights from Columbia to Key Largo?

    Yes. Cheapflights offers flight deals from Columbia to Key Largo by cabin class. In addition to browsing deals, you can also filter by cabin class on the search results page after making a search.

See more FAQs

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Top 2 airlines flying from Columbia to Key Largo

Discover the top 2 airlines that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated July 8, 2026.
AirlineCheapestAverageFlexibilityOn-time
United AirlinesCheapest$268Average$415FlexibilityNo cancel feeOn-time69%
American AirlinesCheapest$308Average$540FlexibilityNo cancel feeOn-time71%

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