$273+ Cheap flights from Columbia, MO (COU) to Key Largo, FL
This is the cheapest one-way flight price found by a Cheapflights user in the last 72 hours by searching for a flight departing on 10/7. Fares are subject to change and may not be available on all flights or dates of travel.
COU — MIA
Jun 23 — Jun 301
Round-trip
1 adult, Economy
We work with more than 300 partners to bring you better travel deals
Find cheap flights from Columbia to Key Largo with Cheapflights
1. Tell us where you want to go
Enter your travel information like dates, passengers, trip type (one-way or round trip), and preferred cabin class then click “Find deals”2. Select your favorite providers
We find the providers serving your travel needs. Choose up to four travel providers to compare side-by-side for flights, hotels, or car rentals.3. Compare prices and book
Review each provider’s pricing and select the best option for you! Book through your favorite provider’s website for a seamless experience.Cheap flight deals from Columbia to Key Largo
Cheapest
Best
Last-minute
One-way
Cheapest flights from Columbia to Key LargoExplore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
Explore the most affordable flight options available from Columbia to Key Largo. Find the lowest fares from popular airlines and budget airlines, with prices last updated on May 24, 2026.
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/47:20 am
COU
- MIA
1 stop7h 18m
American Airlines
Wed 7/812:22 pm
MIA
- COU
1 stop6h 39m
American Airlines
Deal found 5/22![American Airlines logo]()
$308
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/255:19 pm
COU
- MIA
1 stop5h 37m
American Airlines
Sat 8/15:23 pm
MIA
- COU
1 stop5h 29m
American Airlines
Deal found 5/19![American Airlines logo]()
$333
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:19 pm
COU
- MIA
1 stop5h 40m
American Airlines
Sat 6/65:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/20![American Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 7/2911:45 am
COU
- MIA
1 stop7h 50m
American Airlines
Mon 8/34:39 pm
MIA
- COU
1 stop6h 41m
American Airlines
Deal found 5/22![American Airlines logo]()
$374
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 11/75:00 am
COU
- MIA
1 stop5h 53m
United Airlines
Sat 11/148:00 am
MIA
- COU
2 stops14h 20m
United Airlines
Deal found 5/19![United Airlines logo]()
$379
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:00 am
COU
- MIA
1 stop6h 00m
United Airlines
Mon 7/64:10 pm
MIA
- COU
1 stop8h 23m
United Airlines
Deal found 5/23![United Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:44 am
COU
- MIA
1 stop5h 42m
American Airlines
Thu 6/45:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/21![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:36 am
COU
- MIA
2 stops8h 27m
American Airlines
Sat 7/47:57 am
MIA
- COU
1 stop7h 58m
American Airlines
Deal found 5/23![American Airlines logo]()
$404
This American Airlines deal was found by Cheapflights users on 5/24. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/612:43 pm
COU
- MIA
1 stop6h 45m
American Airlines
Sun 8/165:20 am
MIA
- COU
1 stop6h 56m
American Airlines
Deal found 5/24![American Airlines logo]()
$419
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/512:00 pm
COU
- MIA
1 stop6h 55m
American Airlines
Tue 10/135:25 am
MIA
- COU
1 stop6h 52m
American Airlines
Deal found 5/21![American Airlines logo]()
$423
Best flights from Columbia to Key LargoDiscover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
Discover carefully curated flight deals from Columbia to Key Largo that have cost, travel time, and layovers in mind to ensure you get the best travel experience. Data last updated May 24, 2026.
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:00 am
COU
- MIA
1 stop6h 00m
United Airlines
Mon 7/64:10 pm
MIA
- COU
1 stop8h 23m
United Airlines
Deal found 5/23![United Airlines logo]()
$398
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:15 am
COU
- MIA
3 stops11h 42m
United Airlines
Wed 10/141:20 pm
MIA
- COU
2 stops10h 35m
United Airlines
Deal found 5/21![United Airlines logo]()
$480
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 9/18:00 am
COU
- MIA
1 stop5h 54m
United Airlines
Sat 9/53:57 pm
MIA
- COU
1 stop7h 38m
United Airlines
Deal found 5/19![United Airlines logo]()
$483
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/253:25 pm
COU
- MIA
1 stop6h 02m
United Airlines
Sat 8/16:30 am
MIA
- COU
2 stops18h 03m
United Airlines
Deal found 5/19![United Airlines logo]()
$586
This United Airlines deal was found by Cheapflights users on 5/22. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 7/48:00 am
COU
- MIA
1 stop5h 58m
United Airlines
Wed 7/85:22 pm
MIA
- COU
2 stops17h 51m
United Airlines
Deal found 5/22![United Airlines logo]()
$612
This United Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/33:25 pm
COU
- MIA
1 stop6h 02m
United Airlines
Sat 6/67:07 am
MIA
- COU
2 stops17h 26m
United Airlines
Deal found 5/20![United Airlines logo]()
$632
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 8/138:00 am
COU
- MIA
1 stop5h 54m
United Airlines
Mon 8/175:01 pm
MIA
- COU
2 stops22h 29m
United Airlines
Deal found 5/23![United Airlines logo]()
$674
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 8/28:00 am
COU
- MIA
1 stop6h 00m
United Airlines
Fri 8/78:40 pm
MIA
- COU
2 stops14h 33m
United Airlines
Deal found 5/21![United Airlines logo]()
$675
Last-minute flights from Columbia to Key LargoDiscover last-minute flight deals from Columbia to Key Largo. Data last updated May 24, 2026 and is based on user searches.
Discover last-minute flight deals from Columbia to Key Largo. Data last updated May 24, 2026 and is based on user searches.
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 5/2811:44 am
COU
- MIA
1 stop5h 42m
American Airlines
Thu 6/45:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/21![American Airlines logo]()
$403
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/295:19 pm
COU
- MIA
1 stop5h 40m
American Airlines
Mon 6/85:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/23![American Airlines logo]()
$503
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Fri 5/2910:30 am
COU
- MIA
2 stops11h 25m
American Airlines
Sat 6/61:42 pm
MIA
- COU
2 stops8h 42m
American Airlines
Deal found 5/23![American Airlines logo]()
$514
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/306:00 am
COU
- MIA
1 stop5h 39m
American Airlines
Mon 6/85:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/23![American Airlines logo]()
$493
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sat 5/305:19 pm
COU
- MIA
1 stop5h 40m
American Airlines
Sat 6/68:03 am
MIA
- COU
2 stops11h 06m
American Airlines
Deal found 5/23![American Airlines logo]()
$499
This American Airlines deal was found by Cheapflights users on 5/20. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 6/35:19 pm
COU
- MIA
1 stop5h 40m
American Airlines
Sat 6/65:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/20![American Airlines logo]()
$358
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/236:00 am
COU
- MIA
1 stop5h 43m
American Airlines
Mon 6/295:24 am
MIA
- COU
1 stop6h 50m
American Airlines
Deal found 5/19![American Airlines logo]()
$464
This United Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/308:00 am
COU
- MIA
1 stop6h 00m
United Airlines
Mon 7/64:10 pm
MIA
- COU
1 stop8h 23m
United Airlines
Deal found 5/23![United Airlines logo]()
$398
This American Airlines deal was found by Cheapflights users on 5/23. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 6/3010:36 am
COU
- MIA
2 stops8h 27m
American Airlines
Sat 7/47:57 am
MIA
- COU
1 stop7h 58m
American Airlines
Deal found 5/23![American Airlines logo]()
$404
One-way flights from Columbia to Key LargoSearch for one-way flight options from Columbia to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
Search for one-way flight options from Columbia to Key Largo. Find affordable one-way fares based on user searches. Data last updated May 24, 2026.
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Wed 10/76:01 am
COU
- MIA
1 stop13h 16m
American Airlines
Deal found 5/21![American Airlines logo]()
$273
This American Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/157:39 pm
COU
- MIA
1 stop12h 27m
American Airlines
Deal found 5/19![American Airlines logo]()
$284
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/265:00 am
COU
- MIA
2 stops11h 35m
United Airlines
Deal found 5/19![United Airlines logo]()
$304
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 10/45:17 pm
COU
- MIA
1 stop5h 50m
American Airlines
Deal found 5/21![American Airlines logo]()
$343
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Tue 10/66:15 am
COU
- MIA
2 stops11h 42m
United Airlines
Deal found 5/21![United Airlines logo]()
$349
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Mon 10/53:16 pm
COU
- MIA
2 stops22h 31m
United Airlines
Deal found 5/21![United Airlines logo]()
$358
This United Airlines deal was found by Cheapflights users on 5/19. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Sun 11/158:00 am
COU
- MIA
2 stops30h 11m
United Airlines
Deal found 5/19![United Airlines logo]()
$369
This United Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure United Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:15 am
COU
- MIA
1 stop7h 44m
United Airlines
Deal found 5/21![United Airlines logo]()
$414
This American Airlines deal was found by Cheapflights users on 5/21. Clicking the “Pick Dates” button in this card will allow you to select your dates and further customize your flight criteria. From there, click “Find deals”, make sure American Airlines is selected, and click “Compare selected” under the list of providers to see comparable flight deals.
Thu 10/86:01 am
COU
- MIA
2 stops9h 48m
American Airlines
Deal found 5/21![American Airlines logo]()
$420
Find flight deals from Columbia to Key Largo
Keep the following information in mind while searching for Columbia to Key Largo flight deals. Data was last updated May 24, 2026.
Most accurate provider | FlightHub 3 stars |
|---|---|
Most trusted provider | FlightHub 3 stars |
Round-trip from | $308 (American Airlines) |
One-way from | $273 (American Airlines) |
Popular in | December |
Cheapest in | February |
Average price | $531 |
Cheapflights Fare Finder
Customize your flight search to find flights from Columbia to Key Largo that fit within your specific budget. Explore options based on user searches and filter the results based on your desired price range. Find flights that match your budget for a cost-effective journey. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
Use the filters below to find and compare flights from Columbia to Key Largo that are best for you.
Fly from
Fly to
Route
Depart
Return
Cheapest round-trip
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Tue 6/30
8:00 am-3:00 pm
1 stop6h 00m
Miami
Mon 7/6
4:10 pm-11:33 pm
1 stop8h 23m
$398
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Tue 10/6
6:15 am-6:57 pm
3 stops11h 42m
Miami
Wed 10/14
1:20 pm-10:55 pm
2 stops10h 35m
$480
Quickest round-trip
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Tue 9/1
8:00 am-2:54 pm
1 stop5h 54m
Miami
Sat 9/5
3:57 pm-10:35 pm
1 stop7h 38m
$483
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Sat 7/25
3:25 pm-10:27 pm
1 stop6h 02m
Miami
Sat 8/1
6:30 am-11:33 pm
2 stops18h 03m
$586
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Sat 7/4
8:00 am-2:58 pm
1 stop5h 58m
Miami
Wed 7/8
5:22 pm-10:13 am
2 stops17h 51m
$612
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Wed 6/3
3:25 pm-10:27 pm
1 stop6h 02m
Miami
Sat 6/6
7:07 am-11:33 pm
2 stops17h 26m
$632
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Thu 8/13
8:00 am-2:54 pm
1 stop5h 54m
Miami
Mon 8/17
5:01 pm-2:30 pm
2 stops22h 29m
$674
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Sun 8/2
8:00 am-3:00 pm
1 stop6h 00m
Miami
Fri 8/7
8:40 pm-10:13 am
2 stops14h 33m
$675
Cheapest one-way
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Mon 10/26
5:00 am-5:35 pm
2 stops11h 35m
$304
Quickest one-way
ColumbiaMiami
COU - MIA
COUMIA
Columbia Regional
Sun 10/4
5:17 pm-12:07 am
1 stop5h 50m
$343
Showing 1-10 of 16 resultsSorted by cheapest first
Best time to book a flight from Columbia to Key Largo
Have a flexible travel schedule? Discover the best time to fly to Key Largo from Columbia with our price prediction graph.
COU-MIA
Estimated round-trip price
Rates are based on past data. Find the cheapest month and day to book your flight based on your travel requirements, then search for cheap deals.
Cheapflights Insights
Everything you need to know about your flight from Columbia to Key Largo
COU-KE9
COU-MIA
How much does it cost to fly round-trip from Columbia, Missouri to Key Largo?
Reviews of airlines servicing Key Largo
Get insights into the airlines that provide service to Key Largo. Read reviews, discover amenities, and learn about the overall travel experience offered by airlines. Use this information to make informed decisions when choosing an airline for your flight to Key Largo. Reviews last updated May 24, 2026.
See what other customers who have flown with United Airlines and American Airlines from Columbia to Key Largo have to say. You can also see how each airline compares in terms of entertainment options, comfort, food, crew/service, and boarding process.
Boarding
7.7
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Boarding
7.7
Overall
7.4
Comfort
7.3
Entertainment
7.1
Food
6.6
Crew
8.1
Reviews
1 / 20
4.0
OkayDynasty,May 2026
LAX - EWR
Related info for your journey
Find useful and relevant information for your journey from Columbia to Key Largo. Access travel guides, tips, and recommendations to enhance your travel experience. Get information about local attractions, weather, transportation options, and more.
Browse thousands of different options on Cheapflights for your next trip
Toggle through the tabs below to find thousands of options on Cheapflights for your next trip.
Alternative routes
Complete your trip
Flights by cabin class
Other flight options
Other flights from Columbia
Popular flights
Top destinations
Alternative routes for Columbia to Key Largo
See prices for flight routes from nearby airports that may be better suited for you.
Complete your trip
Complete your trip to Key Largo by adding a car rental and/or hotel reservation to your travel itinerary.
Search flights from Columbia to Key Largo by cabin class
Find flights from Columbia to Key Largo, based on your preferred cabin class, be it economy, premium economy, business, or first class.
Columbia and Key Largo flights
Browse other Columbia and Key Largo flight options. Last updated on May 24, 2026.
Other flights from Columbia
Browse through other flights departing from Columbia. Flights are based on user searches made on Cheapflights and were last updated on May 24, 2026.
Popular flight searches
Check out other popular destinations found by fellow travelers in 2026
Columbia to Key Largo flights
Consider these flights traveling from Columbia to Key Largo.
Top 2 airlines flying from Columbia to Key Largo
Discover the top 2 airlines that operate flights from Columbia to Key Largo. Compare their services, reliability, and customer satisfaction ratings to choose the airline that best suits your travel preferences and needs. Over the last 7 days, Cheapflights users made 2,558,603 searches. Data last updated May 24, 2026.
| Airline | Cheapest | Average | Flexibility | On-time |
|---|---|---|---|---|
| Cheapest$268 | Average$426 | FlexibilityNo cancel fee | On-time69% | |
| Cheapest$373 | Average$564 | FlexibilityNo cancel fee | On-time71% |